August 21, 2018 Thesis Open Access

Nygren, Johan

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{
  "publisher": "Zenodo", 
  "DOI": "10.5281/zenodo.1403722", 
  "author": [
    {
      "family": "Nygren, Johan"
    }
  ], 
  "issued": {
    "date-parts": [
      [
        2018, 
        8, 
        21
      ]
    ]
  }, 
  "abstract": "<p>ABSTRACT: The Gorilla Genome Project (Scally, 2012) showed that 30% of the gorilla genome introgressed into the ancestor of humans and chimpanzees, and that the two species diverged through lineage sorting with 15% ending up in <em>Pan</em> and another 15% in <em>Homo</em>. That introgression is the <em>Pan</em>-<em>Homo</em> split, hybridization, which led to speciation as the new hybrid lineages became reproductively isolated from one another.<br>\n<br>\nThe NUMT on chromosome 5 (&ldquo;ps5&rdquo;) (Popadin, 2017) fits perfectly with the introgression speciation model, it was formed from mtDNA that had diverged from the common ancestor of <em>Pan</em>-<em>Homo</em> for 1.8 Myr at the time of insertion into the nuclear genome, and originated in the <em>Gorilla</em> lineage. The ps5 pseudogene was transferred to <em>Pan</em> and <em>Homo</em> during the introgression event that led to the <em>Pan</em>-<em>Homo</em> split, 6 million years ago.</p>", 
  "title": "Introgression from Gorilla caused the Human-Chimpanzee split", 
  "type": "thesis", 
  "id": "1403722"
}