May 28, 2018 Dataset Open Access

Harding, Rachel; Seitova, Alma; Hutchinson, Ashley; Arrowsmith, Cheryl; Edwards, Aled

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        "affiliation": "Structural Genomics Consortium, University of Toronto", 
        "name": "Harding, Rachel", 
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        "affiliation": "Structural Genomics Consortium, University of Toronto", 
        "name": "Seitova, Alma"
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        "affiliation": "Structural Genomics Consortium, University of Toronto", 
        "name": "Hutchinson, Ashley"
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      {
        "affiliation": "Structural Genomics Consortium, University of Toronto", 
        "name": "Arrowsmith, Cheryl"
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        "affiliation": "Structural Genomics Consortium, University of Toronto", 
        "name": "Edwards, Aled"
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    "description": "<p><strong>Project</strong>&nbsp;- Huntingtin structure-function open lab notebook.&nbsp;</p>\n\n<p><strong>Experiment and rationale</strong>&nbsp;-&nbsp;Purified huntingtin samples with stabilising binding partners (e.g. HAP40) are required for use in structural and functional studies, in particular SAXS experiments.&nbsp;</p>", 
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      "HTT", 
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    "notes": "Dr. Harding is the recipient of the Huntington's Disease Society of America Berman Topper Career Development Fellowship which funds and supports this research. The SGC is a registered charity (number 1097737) that receives funds from AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada through Ontario Genomics Institute [OGI-055], Innovative Medicines Initiative (EU/EFPIA) [ULTRA-DD grant no. 115766], Janssen, Merck KGaA, Darmstadt, Germany, MSD, Novartis Pharma AG, Ontario Ministry of Research, Innovation and Science (MRIS), Pfizer, S\u00e3o Paulo Research Foundation-FAPESP, Takeda, and Wellcome.", 
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    "title": "Large scale expression and purification of full-length huntingtin Q23 with HAP40 from baculoviral expression system production in sf9 insect cells \u2013 2018/05/28"
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