Dataset Open Access

The process of HDAC11 Assay Development: Effect of Detergent

Abbey, Megha; Vedadi, Masoud


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  <identifier identifierType="DOI">10.5281/zenodo.1304424</identifier>
  <creators>
    <creator>
      <creatorName>Abbey, Megha</creatorName>
      <givenName>Megha</givenName>
      <familyName>Abbey</familyName>
      <affiliation>Structural Genomics Consortium/University of Toronto</affiliation>
    </creator>
    <creator>
      <creatorName>Vedadi, Masoud</creatorName>
      <givenName>Masoud</givenName>
      <familyName>Vedadi</familyName>
      <affiliation>Structural Genomics Consortium/University of Toronto</affiliation>
    </creator>
  </creators>
  <titles>
    <title>The process of HDAC11 Assay Development: Effect of Detergent</title>
  </titles>
  <publisher>Zenodo</publisher>
  <publicationYear>2018</publicationYear>
  <subjects>
    <subject>HDAC11</subject>
    <subject>histone deacetylase</subject>
    <subject>histone deacetylase 11</subject>
    <subject>assay optimization</subject>
    <subject>HDAC11 assay</subject>
  </subjects>
  <dates>
    <date dateType="Issued">2018-07-03</date>
  </dates>
  <resourceType resourceTypeGeneral="Dataset"/>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://zenodo.org/record/1304424</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsVersionOf">10.5281/zenodo.1304423</relatedIdentifier>
    <relatedIdentifier relatedIdentifierType="URL" relationType="IsPartOf">https://zenodo.org/communities/openlabnotebooks</relatedIdentifier>
    <relatedIdentifier relatedIdentifierType="URL" relationType="IsPartOf">https://zenodo.org/communities/sgc-opennotebook</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="https://creativecommons.org/licenses/by/4.0/legalcode">Creative Commons Attribution 4.0 International</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">&lt;p&gt;The presence of detergent can prevent the sticking of the fluorophore to the sides of the wells of the plate and thus improve the signals. Hence, the effect of detergent was observed on the overall signals and the activity of HDAC11.&lt;/p&gt;</description>
    <description descriptionType="Other">The SGC is a registered charity (number 1097737) that receives funds from AbbVie, Bayer Pharma AG, Boehringer Ingelheim, Canada Foundation for Innovation, Eshelman Institute for Innovation, Genome Canada through Ontario Genomics Institute [OGI-055], Innovative Medicines Initiative (EU/EFPIA) [ULTRA-DD grant no. 115766], Janssen, Merck KGaA, Darmstadt, Germany, MSD, Novartis Pharma AG, Ontario Ministry of Research, Innovation and Science (MRIS), Pfizer, São Paulo Research Foundation-FAPESP, Takeda, and Wellcome.</description>
  </descriptions>
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