Supplementary data - raw unprocessed images, segmentation ground truth and image reconstructions. ************************************************** abbreviations ************************************************** DIC, differential image contrast HMC, Hoffman modulation contrast PC, phase contrast QPI, quantitative phase imaging rDIC-Koos, DIC/HMC image reconstruction according to Koos et al, Sci Rep. 2016;6:30420 rDIC-Yin, DIC/HMC image reconstruction according to Yin et al, Inf Process Med Imaging. 2011;22:384-97. rPC-Yin, PC image reconstruction according to Yin et al, Med Im Anal. 2012; 16(5):1047 rPC-Top-Hat, Top-Hat filter according to Dewan et al, IEEE Transactions on Biomedical Circuits and Systems.2014;8(5):716-728 rWeka, probability map using Trainable Weka segmentation according to Arganda-Carreras et al. Bioinformatics. 2017 ************************************************** folder structure and file and filename description ************************************************** folder "source data+groundtruth" ************************************************** - includes raw microscopic data (uncompressed 16-bit for DIC, HMC and PC, 32-bit for QPI) - includes manualy annotated groundtruth (zip file - imageJ ROI file, 1bit png mask) e.g. DIC_01_raw.tif DIC_01_groundtruth_imagejROI.zip DIC_01_groundtruth_mask.png folder "reconstructions" ************************************************** includes reconstructed images using reconstructions with highest dice coefficient achieved. for DIC and HMC: rDIC-Koos, rDIC-Yin, and rWeka for PC: rPC-Top-Hat, rDIC-Yin, and rWeka for QPI: rWeka note that for rWeka images numbered 01 for DIC, HMC and PC and 01-03 for QPI were used for learning.