Project deliverable Open Access
The number of protein assemblies for which detailed structural information is available represents only a small fraction of the protein assemblies in the cell that can be detected. Computational procedures capable of reliably generating structural models of multiprotein assemblies starting from the atomic coordinates of the individual components, the so-called ‘‘docking’’ methods, therefore play an important role in helping to bridge the gap. The Critical Assessment of Predicted Interactions (CAPRI) has been at the fore-front in this endeavor. If a user has experimental structure of macromolecular complex (target structure) available, and has modelled the constituent components to predict the structure of macromolecular complex using computation methods, the “CAPRI Analyse” server can provide evaluation of the quality of the predicted models. This is the first time users have direct access to the assessment program via a web server.