Journal article Open Access

DNA mismatch repair

Kunkel, Thomas A.; Erie, Dorothy A.


JSON Export

{
  "files": [
    {
      "links": {
        "self": "https://zenodo.org/api/files/b14e1228-5ceb-43e6-a935-6b71e1a3e61d/article.pdf"
      }, 
      "checksum": "md5:9e46edeb1399a348697009b97026f936", 
      "bucket": "b14e1228-5ceb-43e6-a935-6b71e1a3e61d", 
      "key": "article.pdf", 
      "type": "pdf", 
      "size": 444514
    }
  ], 
  "owners": [
    13380
  ], 
  "doi": "10.1146/annurev.biochem.74.082803.133243", 
  "stats": {
    "version_unique_downloads": 120.0, 
    "unique_views": 99.0, 
    "views": 101.0, 
    "version_views": 100.0, 
    "unique_downloads": 120.0, 
    "version_unique_views": 98.0, 
    "volume": 54230708.0, 
    "version_downloads": 122.0, 
    "downloads": 122.0, 
    "version_volume": 54230708.0
  }, 
  "links": {
    "doi": "https://doi.org/10.1146/annurev.biochem.74.082803.133243", 
    "latest_html": "https://zenodo.org/record/1234939", 
    "bucket": "https://zenodo.org/api/files/b14e1228-5ceb-43e6-a935-6b71e1a3e61d", 
    "badge": "https://zenodo.org/badge/doi/10.1146/annurev.biochem.74.082803.133243.svg", 
    "html": "https://zenodo.org/record/1234939", 
    "latest": "https://zenodo.org/api/records/1234939"
  }, 
  "created": "2018-04-28T11:08:28.311495+00:00", 
  "updated": "2020-01-20T17:39:11.696954+00:00", 
  "conceptrecid": "1234938", 
  "revision": 5, 
  "id": 1234939, 
  "metadata": {
    "access_right_category": "success", 
    "doi": "10.1146/annurev.biochem.74.082803.133243", 
    "description": "DNA mismatch repair (MMR) is an evolutionarily conserved process that corrects mismatches generated during DNA replication and escape proofreading. MMR proteins also participate in many other DNA transactions, such that inactivation of MMR can have wide-ranging biological consequences, which can be either beneficial or detrimental. We begin this review by briefly considering the multiple functions of MMR proteins and the consequences of impaired function. We then focus on the biochemical mechanism of MMR replication errors. Emphasis is on structure-function studies of MMR proteins, on how mismatches are recognized, on the process by which the newly replicated strand is identified, and on excision of the replication error.", 
    "license": {
      "id": "CC0-1.0"
    }, 
    "title": "DNA mismatch repair", 
    "relations": {
      "version": [
        {
          "count": 1, 
          "index": 0, 
          "parent": {
            "pid_type": "recid", 
            "pid_value": "1234938"
          }, 
          "is_last": true, 
          "last_child": {
            "pid_type": "recid", 
            "pid_value": "1234939"
          }
        }
      ]
    }, 
    "publication_date": "2005-02-01", 
    "creators": [
      {
        "name": "Kunkel, Thomas A."
      }, 
      {
        "name": "Erie, Dorothy A."
      }
    ], 
    "access_right": "open", 
    "resource_type": {
      "subtype": "article", 
      "type": "publication", 
      "title": "Journal article"
    }
  }
}
101
122
views
downloads
Views 101
Downloads 122
Data volume 54.2 MB
Unique views 99
Unique downloads 120

Share

Cite as