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Mini ReviewHuman Interferons Alpha, Beta and Omega

Bekisz, Joseph; Schmeisser, Hana; Hernandez, Jessica; Goldman, Neil D.; Zoon, Kathryn C.


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{
  "description": "Type I interferons (IFNs), IFN-\u03b1, IFN-\u03b2, IFN-\u03c9, IFN-\u03b4 and IFN-\u03c4 are a family of structurally related, species-specific proteins found only in vertebrates. They exhibit a variety of biological functions, including antiviral, antiproliferative, immunomodulatory and developmental activities. Human Type I IFNs interact with the human IFN alpha receptor (IFNAR), which is composed of two identified subunits (IFNAR-1 and IFNAR-2). The interaction of IFN-\u03b1/\u03b2 with its receptor components results in the activation of a number of signaling pathways. The regulation of specific genes and proteins contributes to the numerous biological functions of Type I IFNs.", 
  "license": "http://creativecommons.org/publicdomain/zero/1.0/legalcode", 
  "creator": [
    {
      "@type": "Person", 
      "name": "Bekisz, Joseph"
    }, 
    {
      "@type": "Person", 
      "name": "Schmeisser, Hana"
    }, 
    {
      "@type": "Person", 
      "name": "Hernandez, Jessica"
    }, 
    {
      "@type": "Person", 
      "name": "Goldman, Neil D."
    }, 
    {
      "@type": "Person", 
      "name": "Zoon, Kathryn C."
    }
  ], 
  "headline": "Mini ReviewHuman Interferons Alpha, Beta and Omega", 
  "image": "https://zenodo.org/static/img/logos/zenodo-gradient-round.svg", 
  "datePublished": "2004-12-01", 
  "url": "https://zenodo.org/record/1234455", 
  "@context": "https://schema.org/", 
  "identifier": "https://doi.org/10.1080/08977190400000833", 
  "@id": "https://doi.org/10.1080/08977190400000833", 
  "@type": "ScholarlyArticle", 
  "name": "Mini ReviewHuman Interferons Alpha, Beta and Omega"
}
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