Journal article Open Access

Therapy Insight: AIDS-related malignancies—the influence of antiviral therapy on pathogenesis and management

Yarchoan, Robert; Tosato, Giovanna; Little, Richard F.


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  <identifier identifierType="URL">https://zenodo.org/record/1233371</identifier>
  <creators>
    <creator>
      <creatorName>Yarchoan, Robert</creatorName>
      <givenName>Robert</givenName>
      <familyName>Yarchoan</familyName>
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    <creator>
      <creatorName>Tosato, Giovanna</creatorName>
      <givenName>Giovanna</givenName>
      <familyName>Tosato</familyName>
    </creator>
    <creator>
      <creatorName>Little, Richard F.</creatorName>
      <givenName>Richard F.</givenName>
      <familyName>Little</familyName>
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  <titles>
    <title>Therapy Insight: AIDS-related malignancies—the influence of antiviral therapy on pathogenesis and management</title>
  </titles>
  <publisher>Zenodo</publisher>
  <publicationYear>2005</publicationYear>
  <dates>
    <date dateType="Issued">2005-08-01</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://zenodo.org/record/1233371</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1038/ncponc0253</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="https://creativecommons.org/publicdomain/zero/1.0/legalcode">Creative Commons Zero v1.0 Universal</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">Patients with HIV infection are at an increased risk of malignancies, especially Kaposi's sarcoma and certain B-cell lymphomas. Highly active antiretroviral therapy has helped to reduce the incidence of many HIV-associated tumors, but as the number of people living with AIDS is increasing, AIDS-associated malignancies will probably rise, posing a significant treatment challenge. Yarchoan et al. discuss the pathogenesis of AIDS-related malignancies, and describe the successful treatments for Kaposi's sarcoma and lymphomas using treatments based on viral, vascular or other pathogenesis-based targets.</description>
  </descriptions>
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