Journal article Open Access

Therapy Insight: AIDS-related malignancies—the influence of antiviral therapy on pathogenesis and management

Yarchoan, Robert; Tosato, Giovanna; Little, Richard F.


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{
  "DOI": "10.1038/ncponc0253", 
  "author": [
    {
      "family": "Yarchoan, Robert"
    }, 
    {
      "family": "Tosato, Giovanna"
    }, 
    {
      "family": "Little, Richard F."
    }
  ], 
  "issued": {
    "date-parts": [
      [
        2005, 
        8, 
        1
      ]
    ]
  }, 
  "abstract": "Patients with HIV infection are at an increased risk of malignancies, especially Kaposi's sarcoma and certain B-cell lymphomas. Highly active antiretroviral therapy has helped to reduce the incidence of many HIV-associated tumors, but as the number of people living with AIDS is increasing, AIDS-associated malignancies will probably rise, posing a significant treatment challenge. Yarchoan et al. discuss the pathogenesis of AIDS-related malignancies, and describe the successful treatments for Kaposi's sarcoma and lymphomas using treatments based on viral, vascular or other pathogenesis-based targets.", 
  "title": "Therapy Insight: AIDS-related malignancies\u2014the influence of antiviral therapy on pathogenesis and management", 
  "type": "article-journal", 
  "id": "1233371"
}
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