Journal article Open Access

Neonatal Tolerance Revisited: Turning on Newborn T Cells with Dendritic Cells

Ridge, J. P.; Fuchs, E. J.; Matzinger, P.


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  <identifier identifierType="URL">https://zenodo.org/record/1231066</identifier>
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    <creator>
      <creatorName>Ridge, J. P.</creatorName>
      <givenName>J. P.</givenName>
      <familyName>Ridge</familyName>
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    <creator>
      <creatorName>Fuchs, E. J.</creatorName>
      <givenName>E. J.</givenName>
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    <creator>
      <creatorName>Matzinger, P.</creatorName>
      <givenName>P.</givenName>
      <familyName>Matzinger</familyName>
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  <titles>
    <title>Neonatal Tolerance Revisited: Turning on Newborn T Cells with Dendritic Cells</title>
  </titles>
  <publisher>Zenodo</publisher>
  <publicationYear>1996</publicationYear>
  <dates>
    <date dateType="Issued">1996-03-22</date>
  </dates>
  <resourceType resourceTypeGeneral="Text">Journal article</resourceType>
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    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsIdenticalTo">10.1126/science.271.5256.1723</relatedIdentifier>
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    <rights rightsURI="https://creativecommons.org/publicdomain/zero/1.0/legalcode">Creative Commons Zero v1.0 Universal</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
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  <descriptions>
    <description descriptionType="Abstract">For some time it has been thought that antigenic challenge in neonatal life is a tolerogenic rather than immunogenic event. Reexamination of the classic neonatal tolerance experiments of Billingham, Brent, and Medawar showed that tolerance is not an intrinsic property of the newborn immune system, but that the nature of the antigen-presenting cell determines whether the outcome is neonatal tolerance or immunization.</description>
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