1229412
doi
10.1006/bbrc.1993.1320
oai:zenodo.org:1229412
Shin, H. S.
Rhee, S. G.
In Vitro Tyrosine Phosphorylation of PLC-γ1 and PLC-γ2 by SRC-Family Protein Tyrosine Kinases
Liao, F.
info:eu-repo/semantics/openAccess
Creative Commons Zero v1.0 Universal
https://creativecommons.org/publicdomain/zero/1.0/legalcode
The phosphorylation of purified phospholipase C-γ1 (PLC-γ1) and PLC-γ2 by src-family-protein tyrosine kinases (PTKs) p56lck p53/56lyn, p59hck, p59fyn, and p60src was studied in vitro. All five PTKs phosphorylated PLC-γ1 and PLC-γ2, suggesting that both PLC-γ isozymes can be phosphorylated in cells by any of the src-fami1y PTKs in response to the activation of cell surface receptors. Comparison of the in vitro phosphorylation rates revealed no distinct specificity between PLC-γ1 and PLC-γ2, or between the five PTKs.
Zenodo
1993-03-01
info:eu-repo/semantics/article
1229411
1579539481.815952
330850
md5:59f22493a0444e3028a047402c5516b9
https://zenodo.org/records/1229412/files/article.pdf
public