Published April 13, 2018 | Version v1
Journal article Open

SUBCLINICAL AND CLINICAL KETOSIS IN SHEEP – RELATIONSHIPS BETWEEN BODY CONDITION SCORES AND BLOOD β- HYDROXYBUTYRATE AND NON-ESTERIFIED FATTY ACIDS CONCENTRATIONS

Creators

  • 1. Faculty of Veterinary Medicine, Trakia University

Description

The study included a total of 136 sheep from two breeds (Lacaune and Mouton Charollais) to establish changes in the values of body condition score (BCS), β-hydroxybutyrate (ВНВА) and non-esterified fatty acids (NEFA) in their blood and their relationship in the development of subclinical (SCK) and clinical (CK) ketosis. The ewes were divided in three groups (pregnant, recently lambed and lactating). Blood concentrations of ВНВА and NEFA were assayed in all ewes. The body condition was scored. Blood ВНВА concentrations were increased in Lacaune sheep from the three groups affected by SCK vs control levels, as well as in animals with CK from all groups vs both controls and SCK. None of Mouton Charollais ewes had blood BHBA concentrations >0.8 mmol/l. The evaluation of BCS of ewes with SCK and CK showed a trend of decrease compared to the control groups. The quantities of NEFA in sheep of the three groups with SCK were statistically significantly elevated vs control groups, while in sheep with CK - decreased, vs both controls and SCK. In meat-type Mouton Charollais ewes, values of NEFA ranged around the reference. 

Files

30-36.pdf

Files (207.1 kB)

Name Size Download all
md5:de7e19aacc68839e7e9a241d1a6fb778
207.1 kB Preview Download

Additional details

Related works

Is compiled by
http://scij-tmvm.com/vol./vol.3/30-36.pdf (URL)

References

  • Al-Mujalli, A. M. (2008). Incidence and clinical study ovine pregnancy toxemia in All-Hassa region, Saudi Arabia. J. Anim. Vet. Adv., 7, 210–212
  • Andrews, A. H., Holland-Howes, V. E. and J. I. D. Wilkinson. (1997). Naturally occurring pregnancy toxaemia in the ewe and treatment with recombinant bovine somatotropin. Small Rumin. Res., 23, 191–197.
  • Anoushepour, A., Mottaghian, P. and M. Sakha. (2014). The comparison of some biochemical parameters in hyperketonemic and normal ewes. Eur. J. Exp. Biology, 4, 83–87.
  • Balikci, E., Yildiz, A. and F. Gurdogan. (2009). Investigation on some biochemical and clinical parameters for pregnancy toxemia in Akkaraman ewes. J. Anim.Vet. Adv., 8, 1268–1273
  • Doepel, L., Lapierre, H. and J. J. Kenneky. (2002). Peripartum performance and metabolism of dairy cows in response to prepartum energy and protein intake. J. Dairy Sci., 85, 2315–2334.
  • Feijó, J. O., Schneider, A., Schmitt, E., Brauner, C. C., Martins, C. F., Barbosa-Ferreira, M., Del Pino, F. A. B., Faria Junior, S. P., Rabassa, V. R. and M. N. Corrêa. (2015). Prepartum administration of recombinant bovine somatotropin (rBST) on adaptation to subclinical ketosis of the ewes and performance of the lambs. Arq. Bras. Med. Vet. Zootec, 67, 103–108.
  • Ferguson, J. D., Galligan, D. T. and N. Thomsen. (1994). Principal descriptors of body condition score in Holstein cows. J. Dairy Sci, 77, 2695–2703.
  • Ferris F. T., Herdson, B. P., Dunnill, S. M. and M. R. Lee. (1969). Toxemia of pregnancy in sheep: a clinical, physiological and pathological study. J. Clin. Invest, 48, 1643–1655
  • Fthenakis, G. C., Arsenos, G., Brozos, C., Fragkou, I. A., Giadinis, N. D., Giannenas, I., Mavrogianni, V. S., Papadopoulos, E. and I. Valasi. (2012). Health management of ewes during pregnancy. Anim. Reprod. Sci., 130, 198–212.
  • Garverick, H. A., Harris, M. N., Vogel-Bluel, R., Sampson, J. D., Bader, J., Lamberson, W. R., Spain, J. N., Lucy, M. C. and R. S. Youngquist. (2013). Concentrations of nonesterified fatty acids and glucose in blood of periparturient dairy cows are indicative of pregnancy success at first insemination. J. Dairy Sci., 96, 181–188.
  • Gupta, V. K., Sharma, S. D., Vihan, V. S. and A. Kumar. (2008). Prevalence and changes in haemogram in subclinical ketosis in sheep reared under organized farming system. Ind. J. Anim. Sci., 78, 453–456.
  • Holtenius, P. and K. Holtenius. (1996). New aspects of ketone bodies in energy metabolism of dairy cows: a review. J Med. A 1996, 43, 579–587.
  • Ingvartsen, K. L. (2006). Feeding and management related diseases in the transition cow. Physiological adaptations around calving and strategies to reduce feeding-related diseases. Anim. Feed Sci. Techn., 126, 175–213.
  • Jefferies, B. C. (1961). Body condition scoring and its use in management. Tasm. J. Agric., 32,19–21.
  • Joshi, N. P., Herdt, T. H. and L. Neuder. (2006). Association of rump fat thickness and plasma NEFA concentration with postpartum metabolic diseases in Holstein cows. Prod Diseases Farm Anim, 9789
  • Karagiannisa, I., Panousisa, N., Kiossisa, E., Tsakmakidisa, I., Lafib, S., Arsenosc, G., Boscosa, C. and Ch. Brozos. (2014). Associations of prelambing body condition score and serum β-hydroxybutyric acid and non-esterified fatty acids concentrations with periparturient health of Chios dairy ewes. Small Rum. Res., 1, 164–173
  • Koyuncu, M. and Ş. Ö. Altınçekiç. (2012). Importance of body condition score in dairy goats. Mac. J. Anim. Sci., 3, 167–173.
  • Lacetera, N., Franci, O., Scalia, D., Bernabucci, U., Ronchi, B. and A. Nardone. (2002). Effects of nonesterified fatty acids and BHB on functions of mononuclear cells obtained from ewes. Am. J. Vet. Res., 63, 414–418
  • López-Gatius, F., Santolaria, P., Yaniz, J., Rutllant, J. and M. López-Béjar. (2002). Factors affecting pregnancy loss from gestation day 38 to 90 in lactating dairy cows from a single herd. Theriogenology, 57, 1251–1261.
  • Marutsova, V. (2016). Comparative studies on the ketosis in ruminants. Dissertation, PhD. Department of Internal medicine, Faculty of Veterinary medicine, Trakia University, Bulgaria
  • Moallem, U., Rozov, A., Gootwine, E. and H. Hoing. (2015). Plasma concentrations of key metabolites and insulin in late-pregnant ewes carrying 1 to 5 fetuses. J. Anim. Sci., 1, 318–324.
  • Panousis, N., Brozos, C., Karagiannis, I., Giadinis, N. D., Lafi, S. and M. Kritsepi-Konstantinou. (2012). Evaluation of Precision Xceed meter for on-site monitoring of blood β-hydroxybutyric acid and glucose concentrations in dairy sheep. Res. Vet. Sci., 93, 435–439
  • Perry, K. W., Janes, A. N., Weekes, T. E. C., Parker, D. S. and D. G. Armstrong. (1994). Glucose and L-lactate metabolism in pregnant and in lactating ewes fed barley - or ground maize-based diets. Exp. Physiol., 79, 35–46
  • Roche, J. R., Bell, A. W., Overton, T. R. and J. J. Loor. (2013). Invited review: Nutritional management of the transition cow in the 21st century – a paradigm shift in thinking. Anim. Product. Sci., 9, 1000–1023
  • Roche, J. R., Meier, S., Heiser, A., Mitchell, M. D., Walker, C. G., Crookenden, M. A., Vailati Riboni, M., Loor, J. J. and J. K. Kay. (2015). Effects of precalving body condition score and prepartum feeding level on production, reproduction, and health parameters in pasture-based transition dairy cows. J. Dairy Sci., 10, 7164–7182.
  • Russel, A. (1984). Condition Scoring of Sheep. In practice, 3, 91.
  • Schlumbohm, C. and J. Harmeyer. (2008). Twin-pregnancy increases susceptibility of ewes to hypoglycaemic stress and pregnancy toxaemia. Res.Vet. Sci., 84, 286–299
  • Sordillo, L. M. and W. Raphael. (2013). Significance of metabolic stress, lipid mobilization and inflammation on transition cow disorders. Vet. Clin. Food Anim, 29: 267–278.
  • Thompson, J. and H. Meyer. (1994). Body Condition Scoring of Sheep. O.S.U. E. Service, Oregon, 4.
  • Van Saun, R. J. (2000). Pregnancy toxaemia in a flock of sheep. J Amer. Vet. Med. Assoc., 217, 1536–1539