Dataset Open Access

# The "social brain" is highly sensitive to the mere presence of social information: An automated meta-analysis and an independent study

Ivy F. Tso1,2*, Saige E. Rutherford1, Yu Fang1, Mike Angstadt1, & Stephan F. Taylor1,2

### Citation Style Language JSON Export

{
"publisher": "Zenodo",
"DOI": "10.5281/zenodo.1210217",
"container_title": "PLoS One",
"language": "eng",
"title": "The \"social brain\" is highly sensitive to the mere presence of social information:   An automated meta-analysis and an independent study",
"issued": {
"date-parts": [
[
2018,
3,
30
]
]
},
"abstract": "<p><strong>Abstract</strong></p>\n\n<p>How the human brain process social information is an increasingly researched topic in psychology and neuroscience, advancing our understanding of basic human cognition and psychopathologies.&nbsp; Neuroimaging studies typically seek to isolate one specific aspect of social cognition when trying to map its neural substrates.&nbsp; It is unclear if brain activation elicited by different social cognitive processes and task instructions are also spontaneously elicited by &nbsp;general social information.&nbsp; In this study, we investigated whether these brain regions are evoked by the mere presence of social information using an automated meta-analysis and confirmatory data from an independent study of simple appraisal of social vs. non-social images.&nbsp; Results of 1,000 published fMRI studies containing the keyword of &ldquo;social&rdquo; were subject to an automated meta-analysis (neurosynth.org). &nbsp;To confirm that significant brain regions in the meta-analysis were driven by a social effect, these brain regions were used as regions of interest (ROIs) to extract and compare BOLD fMRI signals of social vs. non-social conditions in the independent study.&nbsp; The NeuroSynth results indicated that the dorsal and ventral medial prefrontal cortex, posterior cingulate cortex, bilateral amygdala, bilateral occipito-temporal junction, right fusiform gyrus, bilateral temporal pole, and right inferior frontal gyrus are commonly engaged in studies with a prominent social element.&nbsp; The social &ndash; non-social contrast in the independent study showed a strong resemblance of the NeuroSynth map.&nbsp; ROI analyses revealed that a social effect was credible in 8 out of the 11 NeuroSynth regions in the independent dataset.&nbsp; The findings support that the &ldquo;social brain&rdquo; is highly sensitive to the mere presence of social information.&nbsp;</p>",
"author": [
{
"family": "Ivy F. Tso1,2*, Saige E. Rutherford1, Yu Fang1, Mike Angstadt1, & Stephan F. Taylor1,2"
}
],
"type": "dataset",
"id": "1210217"
}
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