Journal article Open Access
Placinta, Gheorghe; Stirbu, Tatiana; Tovba, Lidia
Background: Toxocariasis is a parasitic infection with a major risk to children, especially because of their incompletely developed immune system, high risk of infection or frequent re-infection, all correlated with living standards and personal hygiene. Toxocariasis occurs most frequently occult. However, evident clinical manifestations may be found, due to the migration of larvae in the second stage of development, the degree of toxocara invasion and the immune system of the child.
Material and methods: The study presents the evolution peculiarities in a group of 94 children with toxocara monoinvasion compared to a group of 73 children with the presence of two or more parasitoses. Clinical particularities, representative laboratory indices, treatment and its influence on clinical and paraclinical indices were examined.
Results: The presented article compared the most common clinical signs and paraclinic changes in both studied groups. Was examined the specific treatment for each group of patients and its action on the laboratory indices and especially the influence of treatment on the antibody titer to T. canis.
Conclusions: The most common clinical signs were asthenia, weight loss. An increase in eosinophil level is recorded only in the 13.5% in the cases of Toxocara monoinvasion and in 15.1% of the cases with Toxocariasis associated with other parasites. Anti-toxocara specific therapy proved to be much superior to other medications with a significant reduction in the percentage of eosinophils and total IgE.