11521
doi
10.1155/2014/574159
oai:zenodo.org:11521
user-inmind
user-eu
Jacobs, Volker Rudolf
Department of Obstetrics and Gynecology, Salzburger Landeskrankenhaus (SALK), Paracelsus Medical University, M¨ullner Hauptstrasse 48/Strubergasse 21, 5020 Salzburg, Austria
Fischer, Thorsten
Department of Obstetrics and Gynecology, Salzburger Landeskrankenhaus (SALK), Paracelsus Medical University, M¨ullner Hauptstrasse 48/Strubergasse 21, 5020 Salzburg, Austria
Aigner, Ludwig
Institute of Molecular Regenerative Medicine, Spinal Cord Injury and Tissue Regeneration Center Salzburg, Paracelsus Medical University, Strubergasse 21, 5020 Salzburg, Austria
The maternal brain: an organ with peripartal plasticity.
Hillerer, Katharina Maria
Department of Obstetrics and Gynecology, Salzburger Landeskrankenhaus (SALK), Paracelsus Medical University, M¨ullner Hauptstrasse 48/Strubergasse 21, 5020 Salzburg, Austria
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
<p>The time of pregnancy, birth, and lactation, is characterized by numerous specific alterations in several systems of the maternal body. Peripartum-associated changes in physiology and behavior, as well as their underlying molecular mechanisms, have been the focus of research since decades, but are still far from being entirely understood. Also, there is growing evidence that pregnancy and lactation are associated with a variety of alterations in neural plasticity, including adult neurogenesis, functional and structural synaptic plasticity, and dendritic remodeling in different brain regions. All of the mentioned changes are not only believed to be a prerequisite for the proper fetal and neonatal development, but moreover to be crucial for the physiological and mental health of the mother. The underlying mechanisms apparently need to be under tight control, since in cases of dysregulation, a certain percentage of women develop disorders like preeclampsia or postpartum mood and anxiety disorders during the course of pregnancy and lactation. This review describes common peripartum adaptations in physiology and behavior. Moreover, it concentrates on different forms of peripartum-associated plasticity including changes in neurogenesis and their possible underlying molecular mechanisms. Finally, consequences of malfunction in those systems are discussed.</p>
Zenodo
2014-05-04
info:eu-repo/semantics/article
605823
user-inmind
user-eu
award_title=Imaging of Neuroinflammation in Neurodegenerative Diseases; award_number=278850; award_identifiers_scheme=url; award_identifiers_identifier=https://cordis.europa.eu/projects/278850; funder_id=00k4n6c32; funder_name=European Commission;
1579533161.913852
2199175
md5:ad34a581da6dda84748cc3f91d2afaef
https://zenodo.org/records/11521/files/Hillerer_NeuralPlast_2014-P03.pdf
public
Neural Plast.
2014
574159
2014-05-04