Bézier, Annie
Annaheim, Marc
Herbinière, Juline
Wetterwald, Christoph
Gyapay, Gabor
Bernard-Samain, Sylvie
Wincker, Patrick
Roditi, Isabel
Heller, Manfred
Belghazi, Maya
Pfister-Wilhelm, R.
Periquet, Georges
Dupuy, Catherine
Huguet, Elisabeth
Volkoff, Anne-Nathalie
Lanzrein, Beatrice
Drezen, Jean-Michel
2009-01-01
Many species of parasitoid wasps inject polydnavirus particles in order to manipulate host defenses and development. Because the DNA packaged in these particles encodes almost no viral structural proteins, their relation to viruses has been debated. Characterization of complementary DNAs derived from braconid wasp ovaries identified genes encoding subunits of a viral RNA polymerase and structural components of polydnavirus particles related most closely to those of nudiviruses—a sister group of baculoviruses. The conservation of this viral machinery in different braconid wasp lineages sharing polydnaviruses suggests that parasitoid wasps incorporated a nudivirus-related genome into their own genetic material. We found that the nudiviral genes themselves are no longer packaged but are actively transcribed and produce particles used to deliver genes essential for successful parasitism in lepidopteran hosts.
https://doi.org/10.1126/science.1166788
oai:zenodo.org:1134807
Zenodo
info:eu-repo/semantics/openAccess
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Polydnaviruses of braconid wasps derive from an ancestral nudivirus
info:eu-repo/semantics/article