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Protocol : Assessment of the relationship between sodium intake and pre-specified health outcomes, including dose–response relationships, and integration of different lines of evidence for setting DRVs for sodium

EFSA Panel on Dietetic Products, Nutrition and Allergies; Turck, Dominique; Bresson, Jean-Louis; Burlingame, Barbara; Dean, Tara; Fairweather-Tair, Susan; Heinonen, Marina; Hirsch-Ernst, Karen Ildico; Mangelsdorf, Inge; McArdle, Harry; Neuhäuser-Berthold, Monika; Nowicka, Grazyna; Pentieva, Kristina; Sanz, Yolanda; Siani, Alfonso; Sjödin, Anders; Stern, Martin; Tomé, Daniel; Van Loveren, Henk; Vinceti, Marco; Willatts, Peter; Aggett, Peter; Martin, Ambroise; Przyrembel, Hildegard; Aiassa, Elisa; Ciccolallo, Laura; de Sesmaisons Lecarré, Agnès; Munoz Guajardo, Irene; Valtuena Martinez, Silvia; Naska, Androniki


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  <identifier identifierType="DOI">10.5281/zenodo.1116290</identifier>
  <creators>
    <creator>
      <creatorName>EFSA Panel on Dietetic Products, Nutrition and Allergies</creatorName>
    </creator>
    <creator>
      <creatorName>Turck, Dominique</creatorName>
      <affiliation>University of Lille, France</affiliation>
    </creator>
    <creator>
      <creatorName>Bresson, Jean-Louis</creatorName>
      <affiliation>Clinique des Enfants Malades, Paris, France</affiliation>
    </creator>
    <creator>
      <creatorName>Burlingame, Barbara</creatorName>
      <affiliation>Massey University, New Zealand</affiliation>
    </creator>
    <creator>
      <creatorName>Dean, Tara</creatorName>
      <affiliation>Brighton University, UK</affiliation>
    </creator>
    <creator>
      <creatorName>Fairweather-Tair, Susan</creatorName>
      <affiliation>University of East Anglia, UK</affiliation>
    </creator>
    <creator>
      <creatorName>Heinonen, Marina</creatorName>
      <affiliation>University of Helsinki, Finland</affiliation>
    </creator>
    <creator>
      <creatorName>Hirsch-Ernst, Karen Ildico</creatorName>
      <affiliation>Federal Institute for Risk Assessment (BfR), Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Mangelsdorf, Inge</creatorName>
    </creator>
    <creator>
      <creatorName>McArdle, Harry</creatorName>
      <affiliation>Rowett Research Institute, UK</affiliation>
    </creator>
    <creator>
      <creatorName>Neuhäuser-Berthold, Monika</creatorName>
      <affiliation>Justus Liebig University Giessen, Germany</affiliation>
    </creator>
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      <creatorName>Nowicka, Grazyna</creatorName>
      <affiliation>National Food and Nutrition Institute, Poland</affiliation>
    </creator>
    <creator>
      <creatorName>Pentieva, Kristina</creatorName>
      <affiliation>University of Ulster, UK</affiliation>
    </creator>
    <creator>
      <creatorName>Sanz, Yolanda</creatorName>
      <affiliation>Instituto de Agroquímica y Tecnología de Alimentos, Spain</affiliation>
    </creator>
    <creator>
      <creatorName>Siani, Alfonso</creatorName>
      <affiliation>National Research Council, Italy</affiliation>
    </creator>
    <creator>
      <creatorName>Sjödin, Anders</creatorName>
      <affiliation>University of Copenhagen, Denmark</affiliation>
    </creator>
    <creator>
      <creatorName>Stern, Martin</creatorName>
      <affiliation>University Children's Hospital Tuebingen, Germany</affiliation>
    </creator>
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      <creatorName>Tomé, Daniel</creatorName>
      <affiliation>AgroParisTech, France</affiliation>
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      <creatorName>Van Loveren, Henk</creatorName>
      <affiliation>Maastricht University, the Netherlands</affiliation>
    </creator>
    <creator>
      <creatorName>Vinceti, Marco</creatorName>
      <affiliation>University of Modena e Reggio Emilia, Italy</affiliation>
    </creator>
    <creator>
      <creatorName>Willatts, Peter</creatorName>
      <affiliation>School of Psychology, University of Dundee, UK</affiliation>
    </creator>
    <creator>
      <creatorName>Aggett, Peter</creatorName>
      <affiliation>University of Lancashire, UK</affiliation>
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    <creator>
      <creatorName>Martin, Ambroise</creatorName>
      <affiliation>Faculté de Médecine Lyon, France</affiliation>
    </creator>
    <creator>
      <creatorName>Przyrembel, Hildegard</creatorName>
      <affiliation>Federal Institute for Risk Assessment  (Bfr), Germany</affiliation>
    </creator>
    <creator>
      <creatorName>Aiassa, Elisa</creatorName>
      <affiliation>EFSA</affiliation>
    </creator>
    <creator>
      <creatorName>Ciccolallo, Laura</creatorName>
      <affiliation>EFSA</affiliation>
    </creator>
    <creator>
      <creatorName>de Sesmaisons Lecarré, Agnès</creatorName>
      <affiliation>EFSA</affiliation>
    </creator>
    <creator>
      <creatorName>Munoz Guajardo, Irene</creatorName>
      <affiliation>EFSA</affiliation>
    </creator>
    <creator>
      <creatorName>Valtuena Martinez, Silvia</creatorName>
      <affiliation>EFSA</affiliation>
    </creator>
    <creator>
      <creatorName>Naska, Androniki</creatorName>
      <affiliation>University of Athens, Greece</affiliation>
    </creator>
  </creators>
  <titles>
    <title>Protocol : Assessment Of The Relationship Between Sodium Intake And Pre-Specified Health Outcomes, Including Dose–Response Relationships, And Integration Of Different Lines Of Evidence For Setting Drvs For Sodium</title>
  </titles>
  <publisher>Zenodo</publisher>
  <publicationYear>2017</publicationYear>
  <subjects>
    <subject>dietary reference value</subject>
    <subject>nutrition</subject>
    <subject>sodium</subject>
    <subject>bone</subject>
    <subject>cardiovascular</subject>
    <subject>systematic review</subject>
    <subject>protocol</subject>
    <subject>blood pressure</subject>
    <subject subjectScheme="url">http://id.agrisemantics.org/gacs/C1698</subject>
    <subject subjectScheme="url">http://id.agrisemantics.org/gacs/C99</subject>
    <subject subjectScheme="url">http://id.agrisemantics.org/gacs/C10616</subject>
    <subject subjectScheme="url">http://id.agrisemantics.org/gacs/C900</subject>
    <subject subjectScheme="url">http://id.agrisemantics.org/gacs/C2924</subject>
    <subject subjectScheme="url">http://id.agrisemantics.org/gacs/C2861</subject>
  </subjects>
  <dates>
    <date dateType="Issued">2017-12-14</date>
  </dates>
  <language>en</language>
  <resourceType resourceTypeGeneral="Text">Other</resourceType>
  <alternateIdentifiers>
    <alternateIdentifier alternateIdentifierType="url">https://zenodo.org/record/1116290</alternateIdentifier>
  </alternateIdentifiers>
  <relatedIdentifiers>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsCitedBy">10.2903/sp.efsa.2017.EN-1356</relatedIdentifier>
    <relatedIdentifier relatedIdentifierType="DOI" relationType="IsPartOf">10.5281/zenodo.1116289</relatedIdentifier>
  </relatedIdentifiers>
  <rightsList>
    <rights rightsURI="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution 4.0</rights>
    <rights rightsURI="info:eu-repo/semantics/openAccess">Open Access</rights>
  </rightsList>
  <descriptions>
    <description descriptionType="Abstract">&lt;p&gt;As part of a series of scientific opinions on dietary references values (DRVs) for micronutrients for the European population, the EFSA&amp;nbsp;Panel on Dietetics Products, Nutrition and Allergies (NDA)&amp;nbsp;&amp;nbsp;is reviewing the scientific evidence to set DRVs for sodium.&lt;/p&gt;

&lt;p&gt;The protocol presented in this document describes the methodology that will be&amp;nbsp;applied for: i) the assessment of possible relationships between sodium intake and health outcomes, including dose-response relationship(s), where applicable, and ii) the integration of different lines of evidence for setting DRVs. In particular,&amp;nbsp;systematic reviews on the relationship between sodium intake and blood pressure, cardiovascular disease, bone mineral density, bone mineral content, and osteoporotic fractures will be conducted.&amp;nbsp;&lt;/p&gt;

&lt;p&gt;The protocol will be implemented in 2018. The outcome will be used&amp;nbsp;by the NDA Panel to complete&amp;nbsp;its scientific opinion on DRVs for sodium.&amp;nbsp;A public consultation will be organised once the scientific opinion is complete (Spring 2019; https://www.efsa.europa.eu/en/calls/consultations). This protocol will be published as an Annex to the scientific opinion (Annex A).&lt;/p&gt;

&lt;p&gt;Further information EFSA&amp;#39;s work on DRVs: https://www.efsa.europa.eu/en/topics/topic/dietary-reference-values-and-dietary-guidelines&lt;/p&gt;</description>
    <description descriptionType="Other">Contact: agnes.desesmaisons-lecarre@efsa.europa.eu; nda@efsa.europa.eu</description>
  </descriptions>
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