СТАН МЕМБРАН ЕРИТРОЦИТІВ У ХВОРИХ НА ЛІКАРСЬКУ ХВОРОБУ

The research data of erythrocyte membrane condition in 92 patients both with acute and latent drug disease (DD) are represented. The control group consisted of 30 practically healthy donors. The erythrocyte link is a sensitive system directly involved in mechanisms for the development of sensitization to drugs, as evidenced by a change in their erythrocytometric indices and membranes structures. The patients with DD revealed to have the increase in erythrocyte macroforms, malfunction of electrical characteristics of erythrocyte membranes as well as high resistance to acid hemolysis. Erythrocyte membrane condition malfunctions have been mostly observed in patients with DD associated with allergic dermatoses. The research of structural and functional erythrocyte membrane condition will allow to get additional information about pathological process gravity as well as to estimate efficacy of therapy and to create individual prognosis of pathological process course.