Published October 5, 2013 | Version 17287
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A Computational Fluid Dynamic Model of Human Sniffing

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The objective of this paper is to develop a computational model of human nasal cavity from computed tomography (CT) scans using MIMICS software. Computational fluid dynamic techniques were employed to understand nasal airflow. Gambit and Fluent software was used to perform CFD simulation. Velocity profiles, iteration plots, pressure distribution, streamline and pathline patterns for steady, laminar airflow inside the human nasal cavity of healthy and also infected persons are presented in detail. The implications for olfaction are visualized. Results are validated with the available numerical and experimental data. The graphs reveal that airflow varies with different anatomical nasal structures and only fraction of the inspired air reaches the olfactory region. The Deviations in the results suggest that the treatment of infected volunteers will improve the olfactory function.

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References

  • <p>
  • Gary S. Settles, "Sniffers: Fluid-Dynamic Sampling for Olfactory Trace Detection in Nature and Homeland Security"- The 2004 Freeman Scholar Lecture.
  • Elad D, Liebental R, Wening B L, Einav S. Analysis of air flow patterns in the human nose. Med and Biol Eng and Comput 1993; 31:585- 592.
  • Keyhani K., Scherer P.W. and Mozell M.M., Numerical Simulation of Airflow in the Human Nasal Cavity, J. Biomech Eng., 117, 1995, 429-441.
  • Subramaniam R.P., Richardson R.B., Morgan K.T., Kimbell J.S. and Guilmette R.A., Computational Fluid Dynamics Simulations of Inspiratory Airflow in the Human Nose and Nasopharynx, Inhal. Toxicol., 10,1998,91–120.
  • Wang K., Jr.T.S.D., Morrison E.E., Vodyanoy V.J., Numerical Simulation of Air Flow in the Human Nasal Cavity, Proceeding of the 2005 IEEE, 2005,5607-5610.
  • J.Wen 1, K.Inthavong1, Z.F.Tian1, J.Y.Tu1, C.L.Xue2 and C.G.Li2 Airflow Patterns in Both Sides of a Realistic Human Nasal Cavity for Laminar and Turbulent Conditions, "16th Australian Fluid Mechanics Conference, Crown Plaza, Gold Coast, Australia, 2-7 December 2007, pp. 68-74.
  • Zhao K, Scherer PW, Hajiloo SA, Dalton P. Effect of anatomy on human nasal airflow and odorant transport patterns. Chem Senses 2004; 29(5): 365-379.
  • John F. Wendt Editor, Computational Fluid Dynamics An Introduction, with contributions by John D. Anderson Jr., Joris Degroote, Gerard Degrez, Erik Dick, Roger Grundmann and Jan Vierendeels, Third Edition. ISBN: 978-3-540-85055-7.
  • Joel Guerrero, Numerical Simulation of the unsteady Aerodynamics of flapping flight, Thesis chapter 3, pp, 34-51. [10] Kelly J.T., Prasad A.k., and Wexler A.S., Detailed Flow Patterns in the Nasal Cavity, J Appl. Physiol., 89, 2000,323-337.</p>