10.5281/zenodo.1088006
https://zenodo.org/records/1088006
oai:zenodo.org:1088006
Sadegh Masoudi
Sadegh Masoudi
Ali Asghar Yousefi
Ali Asghar Yousefi
Somayeh Nourollahi
Somayeh Nourollahi
Fatemeh Noughani
Fatemeh Noughani
Absorbed Dose Measurement in Gonads Menduring Abdominal and Pelvicradiotherapy
Zenodo
2013
Absorbed Dose
Abdominal and pelvic
gonads men
Radiotherapy.
2013-10-01
eng
10.5281/zenodo.1088005
https://zenodo.org/communities/waset
16877
Creative Commons Attribution 4.0 International
Two different testicular tissues have to be distinguished in regard to radiation damage: first the seminiferous tubules, corresponding to the sites of spermatogenesis, which are extremely radiosensitive. Second the testosterone secreting Leydig cells, which are considered to be less radiosensitive. This study aims to estimate testicular dose and the associated risks for infertility and hereditary effects from Abdominal and pelvic irradiation. Radiotherapy was simulated on a humanoid phantom using a 15 MV photon beam. Testicular dose was measured for various field sizes and tissue thicknesses along beam axis using an ionization chamber and TLD. For transmission Factor Also common method of measuring the absorbed dose distribution and electron contamination in the build-up region of high-energy beams for radiation therapy is by means of parallel-plate Ionisation chambers. Gonadal dose was reduced by placing lead cups around the testes supplemented by a field edge block. For a tumor dose of 100 cGy, testicular dose was 2.96-8.12 cGy depending upon the field size and the distance from the inferior field edge. The treatment at parameters, the presence of gonad shield and the somatometric characteristics determine whether testicular dose can exceed 1 Gy which allows a complete recovery of spermatogenesis.