Journal article Open Access
Bernaz, Emilian P.; Ciobani, Gheorghe Ch.; Tentiuc, Elizaveta V.; Borovic, Eduard I.; Vovc, Liviu A.
Background: Antibiotics have had a profound impact on humanity’s health, by improving our ability to prevent, cure and reduce the transmission of many infectious diseases. It is widely known, that the unnecessary or inappropriate use of antibiotics, occurs up to 50% of prescriptions only in the United States and Canada. Fortunately all negative impact on the human health can be roughly imagined.
Material and methods: For this study we used the data of a six-year (2009-2014) period in the Emergency Medicine Institute and their main subdivisionswhich show the consumption dynamics of antibacterials use in natural indexes.
Results: The total annual medium consumption of antimicrobials was registered as the following: ICD 1796.98 DDD/1000, SSOTD 566.12 DDD/1000and EMI 584.05DDD/1000, with the parenteral to enteral forms share of respectively 94.67% to 5.33%, 85.62% to 14.38% and 83.52% to 16.48%. Five fromnine main groups: beta-lactam antibacterials, penicilins, other beta-lactam, aminoglycoside, other antibacterials and quinolone antibacterials registeredaround 90% of all antibiotics consumption. Comparatively to Australian hospitals and hospitals other worldwide countries in EMI consumption perDDD/1000 was lower: by 3.39 and 2.22 times for tetracyclines, by 5.1 and 4.63 for beta-lactam and penicilins, as well as by 2.55 and 1.63 for macrolidesand lincosamides.
Conclusions: The obtained data about the dynamics of antibacterials consumption in EMI and their main departments, in comparison with hospitalsfrom other worldwide countries, represents important arguments and reserves for improving quality treatment, planning, rational prescription andutilization of antibiotics in hospitals.