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Journal article Open Access

The use of platelet-rich plasma in anti-aging therapy

Chorążewska Małgorzata; Piech Piotr; Pietrak Justyna; Kozioł Maciej; Obierzyński Paweł; Maślanko Monika; Wilczyńska Karolina; Tulwin Tytus; Łuczyk Rober

Chorążewska Małgorzata, Piech Piotr, Pietrak Justyna, Kozioł Maciej, Obierzyński Paweł, Maślanko Monika, Wilczyńska Karolina, Tulwin Tytus, Łuczyk Robert. The use of platelet-rich plasma in anti-aging therapy..Journal of Education, Health and Sport. 2017;7(11):162-175. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1045532

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https://pbn.nauka.gov.pl/sedno-webapp/works/837145

 

 

 

 

 

The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26.01.2017).

1223 Journal of Education, Health and Sport eISSN 2391-8306 7

© The Authors 2017;

This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland

Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium,

provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License

(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.

This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial

use, distribution and reproduction in any medium, provided the work is properly cited.

The authors declare that there is no conflict of interests regarding the publication of this paper.

Received: 20.10.2017. Revised: 21.10.2017. Accepted: 12.11.2017.

 

 

 

THE USE OF PLATELET-RICH PLASMA IN ANTI-AGING THERAPY

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Małgorzata Chorążewska [1], Piotr Piech [2,3], Justyna Pietrak [4,5], Maciej Kozioł [3], Paweł Obierzyński [3,6], Monika Maślanko [4,5], Karolina Wilczyńska [4], Tytus Tulwin [8], Robert Łuczyk [7].

 

 

[1] Uniwersytet Medyczny w Szczecinie - absolwent, praktyka prywatna w Szczecinie.

[2] Klinika Ortopedii i Traumatologii SPSK4 w Lublinie

[3] Zakład Anatomii Prawidłowej, Uniwersytet Medyczny w Lublinie

[4] Zakład Protetyki Stomatologicznej, Uniwersytet Medyczny w Lublinie

[5] Katedra i Zakład Stomatologii Wieku Rozwojowego, Uniwersytet Medyczny w Lublinie

[6] Studeckie Koło Naukowe przy Katedrze i Zakładzie Anatomii Prawidłowej Człowieka, Uniwersytet Medyczny w Lublinie

[7] Katedra Interny z Zakładem Pielęgniarstwa Internistycznego, Wydział Nauk o Zdrowiu, Uniwersytet Medyczny w Lublinie

[8] Katedra Termodynamiki, Mechaniki Płynów i Napędów Lotniczych, Politechnika Lubelska

 

ABSTRACT

Introduction

Aging stands for the changes in the human body, which are recognized as natural processes that concern every person and are related to the passage of time. Despite 'normalness' of the process, a tendency is emerging to treat aging as a pathology requiring proper diagnostics. Consequently, an 'anti-aging' medicine has been established - defined as study of preventing and slowing down the process of aging.

Aim of the study

The aim of this study is to summarize and present the current knowledge, based on the overview of writing on the properties and effectiveness of the use of PRP in anti-aging therapy. 

 

Description of knowledge

 

Autologous platelet-rich plasma is a concentrate of human blood platelets suspended in a small amount of plasma, wherein concentration of thrombocytes is higher than initial concentration. For autologous plasma to have high healing properties, platelet levels should be at least 1 million in 5 ml of plasma.

The basic condition for initiating repair and regenerative processes in vivo is the formation of a blood clot. Also, by degranulating, platelets release many growth factors, such as PDGF, TGF-β, EGF, FGF, VEGF and others, which are involved not only in blood coagulation, but also in immune response and tissue healing.

The large variety of PRP-obtaining methods and the range of concentration levels of growth factors in PRP may lead to ambiguity in the literature, as to the extent to which formulation was actually used in a variety of preclinical and clinical studies. Some of those studies are presented in this article.

 

Summary

 

Platelet-rich treatments are part of the growing popularity of regenerative medicine, which is beginning to be recognized as the medicine of the future. However, without proper control methods or optimization of numerous variables (e.g. concentration or ratio of growth factors) during PRP preparation, it is not known which ingredients are needed and preferred, and which are harmful for tissue regeneration.

However, numerous studies show PRP injection as a promising method of rejuvenating the skin, therefore platelet-rich treatments are an important part of the growing popularity of regenerative medicine.

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