Journal article Open Access
Koza Jarosław; Orłowski Krzysztof; Jurgoński Adam; Meder Agnieszka; Pujanek Małgorzata; Ameryk Monika; Kwiatkowska Renata; Świątkowski Maciej
Koza Jarosław, Orłowski Krzysztof, Jurgoński Adam, Meder Agnieszka, Pujanek Małgorzata, Ameryk Monika, Kwiatkowska Renata, Świątkowski Maciej. Screening for hepatocellular carcinoma..Journal of Education, Health and Sport. 2017;7(11):152-161. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.1045341
The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26.01.2017).
1223 Journal of Education, Health and Sport eISSN 2391-8306 7
© The Authors 2017;
This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland
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provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License
(http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.
This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted, non commercial
use, distribution and reproduction in any medium, provided the work is properly cited.
The authors declare that there is no conflict of interests regarding the publication of this paper.
Received: 20.10.2017. Revised: 21.10.2017. Accepted: 11.11.2017.
Screening for hepatocellular carcinoma
Jarosław Koza1, Krzysztof Orłowski1, Adam Jurgoński2, Agnieszka Meder1, Małgorzata Pujanek1, Monika Ameryk1, Renata Kwiatkowska1, Maciej Świątkowski1
1 Department of Gastroenterology and Nutrition Disorders, Nicolaus Copernicus University in Toruń, Faculty of Health Sciences, Collegium Medicum in Bydgoszcz, Poland
2 Division of Food Science, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, Olsztyn, Poland
Jarosław Koza, Department of Gastroenterology and Nutrition Disorders,
University Hospital no. 2, Ujejskiego 75 Str, 85-168 Bydgoszcz, Poland;
Introduction and purpose of the work. Hepatocellular carcinoma (HCC) is one of the most common malignant tumours all over the world. It is considered to be the sixth malignant tumour in terms of incidence. It is also characterized by high mortality rate, which, depending on the geographic region, gives the second or third place on the list of cancer related death. There are many known risk factors for the development of hepatocellular carcinoma, the most important of which is liver cirrhosis. Thus the cirrhotic patients are generally accepted for screening. Actually it is recommended to perform abdominal ultrasound every 6 months in this group. Other forms of screening are also tested.
Description of the current knowledge and conclusions.
Literature review provides indisputable evidences for the need of screening for liver cancer. Doubts remain only about the appropriateness of widening the screening group and possibly extending the scope of diagnostic tools.
The authors, by analyzing the available knowledge for hepatocellular carcinoma screening, consider the qualification of actually recommended screening tests to be insufficient in countries with high incidence. Relatively high incidence of HCC, even greater mortality in the context of all cancers, safety, low cost and universal access to ultrasound, should, in the opinion of the authors, be enough for the consideration to widen the screening guidelines in countries with high incidence of HCC. In countries with low incidence, e.g. in Poland, the screening in healthy population do not belong to the priority.
Key words: hepatocellular carcinoma, screening, liver cirrhosis, HCC