path A+ A+.ind A- A-.ind B B.ind E+ E+.ind E- E-.ind E E.ind N N.ind O O.ind K K.ind Z Z.ind bleeding|nmod|start_entity bleeding|nmod|users users|nmod|inhibitors inhibitors|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 7.000000 0 8.000000 0 16.000000 0 1.000000 0 5.000000 0 0.000000 0 treatment|nmod|start_entity caused|nsubj|treatment caused|nmod|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthesis|nmod|start_entity analogues|nsubj|synthesis analogues|nmod|modulators modulators|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 phosphorylation|amod|start_entity phosphorylation|nmod|correlates correlates|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity response|nmod|levels correlated|nsubjpass|response correlated|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 glucose-6-phosphate|nmod|start_entity utilization|amod|glucose-6-phosphate dephosphorylation|nmod|utilization catalyzes|dobj|dephosphorylation catalyzes|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 sensitivity|amod|start_entity activity|appos|sensitivity led|nsubj|activity led|nmod|analysis analysis|acl|demonstrating demonstrating|ccomp|metabolized metabolized|nmod|serum serum|nmod|patients patients|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 kinases|compound|start_entity participate|nsubj|kinases participate|nmod|end_entity 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 therapy|compound|start_entity kinetics|nmod|therapy kinetics|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 repair|amod|start_entity component|nmod|repair excision_repair_cross-complementation_group_1|acl:relcl|component excision_repair_cross-complementation_group_1|appos|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 plays|nsubj|start_entity plays|advcl|attenuate attenuate|dobj|hypertrophy hypertrophy|nmod|receptors receptors|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 agonists|amod|start_entity reported|nsubjpass|agonists marketed|ccomp|reported pursued|advcl|marketed pursued|nsubjpass|modulators modulators|compound|end_entity 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 minimal|nsubj|start_entity altered|advcl|minimal altered|nsubjpass|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 site|amod|start_entity neurons|nmod|site interacts|nmod|neurons interacts|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 inhibitor|amod|start_entity reduced|nsubj|inhibitor reduced|dobj|activity activity|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 effective|nsubj|start_entity effective|advcl|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 10.000000 0 0.000000 0 0.000000 0 0.000000 0 assess|advcl|start_entity assess|dobj|role role|nmod|mutations mutations|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 11.000000 0 0.000000 0 1.000000 0 0.000000 0 vanilloid|nmod|start_entity vanilloid|dobj|channel channel|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 benzo|amod|start_entity pyrene_3|nsubj|benzo showed|parataxis|pyrene_3 showed|nsubj|isoforms isoforms|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 channel|compound|start_entity along|nmod|channel 1.3|advmod|along k|dep|1.3 k|dep|channels channels|appos|task1 task1|dep|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 absorption|compound|start_entity inhibits|dobj|absorption hormone|acl:relcl|inhibits hormone|nsubj|peptide peptide|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 11.000000 0 0.000000 0 4.000000 0 12.000000 0 1.000000 0 benzoic_acid|appos|start_entity 4|dep|benzoic_acid inhibitor|dep|4 used|dep|inhibitor used|advcl|support support|ccomp|acting acting|xcomp|reduce reduce|nmod|action action|nmod|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 deaminase|compound|start_entity unassigned|dep|deaminase unassigned|appos|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 2.000000 0 depletion|compound|start_entity loaded|nmod|depletion iron|acl|loaded values|nmod|iron observed|nmod|values observed|nsubjpass|staining staining|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 7.000000 0 2.000000 0 0.000000 0 targets|nmod|start_entity targets|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitor|amod|start_entity inhibitor|appos|blocker blocker|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 action|nmod|start_entity action|nmod|release release|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 treatment|nmod|start_entity increased|nsubj|treatment increased|dobj|concentrations concentrations|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 2.000000 0 1.000000 0 12.000000 0 0.000000 0 5.000000 0 12.000000 0 1.000000 0 analogues|nmod|start_entity analogues|dep|studies studies|nmod|subtypes subtypes|amod|adenosine adenosine|dep|a1 a1|nummod|end_entity 0.000000 0 0.000000 0 15.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 diuretics|dep|start_entity diuretics|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 kinases|compound|start_entity subgroup|nmod|kinases kinases|acl:relcl|subgroup family|nmod|kinases member|nmod|family member|nsubj|tyrosine_kinase tyrosine_kinase|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 measures|compound|start_entity based|nmod|measures overload|dep|based had|dobj|overload had|nsubj|c282y c282y|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 stimulated|nmod|start_entity seen|xcomp|stimulated begun|advcl|seen begun|xcomp|investigating investigating|dobj|sequence sequence|nmod|region region|nmod|gene gene|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 counteraction|nmod|start_entity counteraction|nmod|release release|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 circulates|nsubj|start_entity circulates|nmod|blood blood|amod|bound bound|nmod|sex_hormone-binding_globulin sex_hormone-binding_globulin|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 assays|nummod|start_entity revealed|nsubj|assays revealed|ccomp|had had|nsubj|medium medium|acl|containing containing|dobj|region region|nmod|end_entity 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 space|nmod|start_entity clears|dobj|space plays|advcl|clears plays|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 metabolism|compound|start_entity related|nmod|metabolism related|nsubjpass|genotype genotype|nmod|aldehyde_dehydrogenase_2 aldehyde_dehydrogenase_2|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 function|nsubj|start_entity function|nmod|mechanism mechanism|nmod|regulation regulation|nmod|release release|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|dep|transport transport|nsubj|+ +|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 biosynthesis|amod|start_entity enzyme|nmod|biosynthesis glycerol-3-phosphate_dehydrogenase|nsubj|enzyme glycerol-3-phosphate_dehydrogenase|appos|product product|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 levels|nmod|start_entity investigated|dobj|levels investigated|nmod|corticotrophin-releasing_hormone corticotrophin-releasing_hormone|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 absorption|compound|start_entity limit|dobj|absorption lumen|acl|limit back|nmod|lumen work|advmod|back requires|advcl|work requires|dobj|proteins proteins|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 coinfusion|nmod|start_entity affected|nmod|coinfusion affected|nsubjpass|response response|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 homolog|amod|start_entity homolog|acl|deleted deleted|nmod|chromosome chromosome|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 associated|nsubjpass|start_entity associated|nmod|rbf rbf|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 species|compound|start_entity increase|iobj|species undergo|ccomp|increase undergo|parataxis|up-regulated up-regulated|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 suggesting|nmod|start_entity suggesting|dobj|role role|nmod|activation activation|compound|end_entity 3.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 3.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 homeostasis|amod|start_entity exploited|nmod|homeostasis exploited|nmod|design design|nmod|effectors effectors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibition|nmod|start_entity promoted|nsubj|inhibition promoted|nmod|downregulation downregulation|nmod|activity activity|compound|end_entity 0.000000 0 2.000000 0 0.000000 0 1.000000 0 2.000000 0 2.000000 0 13.000000 0 0.000000 0 1.000000 0 0.000000 0 kinase|nsubj|start_entity kinase|ccomp|promotes promotes|nsubj|end_entity 0.000000 0 0.000000 0 14.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 concentration|compound|start_entity concentration|nsubj|concentration concentration|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 %|nmod|start_entity testosterone|amod|% given|dobj|testosterone animals|acl|given increased|nmod|animals increased|nsubjpass|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 resistance|compound|start_entity model|nmod|resistance developed|dobj|model developed|advcl|examine examine|dobj|effects effects|nmod|inhibition inhibition|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 processes|nsubj|start_entity processes|dobj|downregulation downregulation|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 bb|appos|start_entity modulates|nsubj|bb modulates|nmod|line line|nmod|view view|appos|administration administration|nmod|gastrin-releasing_peptide gastrin-releasing_peptide|appos|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 necessary|nmod|start_entity necessary|nmod|induction induction|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|compound|start_entity associated|nmod|uptake associated|nsubjpass|mutation mutation|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 delivery|compound|start_entity essential|nmod|delivery erythropoiesis|acl:relcl|essential involved|nmod|erythropoiesis genes|acl:relcl|involved regulate|dobj|genes regulate|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentrations|amod|start_entity increased|nmod|concentrations increased|nsubj|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 accumulation|nmod|start_entity generated|nsubj|accumulation generated|nmod|il-1r il-1r|acl|regulated regulated|dobj|expression expression|acl:relcl|induced induced|nmod|activation activation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 have|advcl|start_entity have|nsubj|subjects subjects|ref|who respond|nsubj|who respond|nmod|inhibitors inhibitors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 oxidases|amod|start_entity active|nmod|oxidases showed|dep|active showed|dobj|activity activity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 dose|nmod|start_entity oxidase|nmod|dose oxidase|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 biosynthesis|compound|start_entity activator|nmod|biosynthesis srebp-2|appos|activator sites|nmod|srebp-2 observe|nmod|sites observe|dobj|co-localization co-localization|nmod|sites sites|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 utilization|compound|start_entity altered|nsubjpass|utilization altered|nmod|concentrations concentrations|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 doses|nmod|start_entity started|nmod|doses started|advcl|have have|dobj|impaired_renal_function impaired_renal_function|acl:relcl|prolong prolong|dobj|half-life half-life|nmod|inhibitors inhibitors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 8.000000 0 0.000000 0 2.000000 0 0.000000 0 group|compound|start_entity increased|nmod|group increased|nsubjpass|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 8.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|dep|lack lack|nmod|association association|nmod|polymorphisms polymorphisms|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 n-oxygenation|nmod|start_entity suppression|nmod|n-oxygenation compared|nsubjpass|suppression compared|xcomp|using using|dobj|proteins proteins|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 homeostasis|compound|start_entity regulating|dobj|homeostasis elements|acl|regulating one|nmod|elements one|nsubj|calcium-sensing_receptor calcium-sensing_receptor|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 phosphorylated|amod|start_entity active|dep|phosphorylated epor|acl:relcl|active associated|nmod|epor end_entity|acl|associated 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 compared|advcl|start_entity compared|dobj|antagonists antagonists|compound|end_entity 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 produce|nsubj|start_entity produce|nmod|modulation modulation|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 residue|compound|start_entity srsf2|nmod|residue acetylates|dobj|srsf2 acetylates|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 allow|nmod|start_entity allow|nsubj|component component|compound|end_entity 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|nmod|start_entity macrophages|nmod|treatment gene|nmod|macrophages gene|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 evaluation|nmod|start_entity comparing|nsubj|evaluation comparing|xcomp|blocking blocking|nsubj|inhibitor inhibitor|compound|end_entity 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 mimics|nsubj|start_entity mimics|dobj|actions actions|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 metabolism|compound|start_entity regulated|nmod|metabolism regulated|nsubjpass|splicing splicing|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 residues|amod|start_entity sections|nmod|residues structures|nmod|sections combining|dobj|structures generating|advcl|combining generating|dobj|model model|nmod|rod rod|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 channel|compound|start_entity characterization|nmod|channel shows|nsubj|characterization shows|ccomp|related related|nmod|channel channel|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 efflux|nmod|start_entity efflux|nmod|mutants mutants|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 production|amod|start_entity stimulation|nmod|production induction|dep|stimulation roles|nmod|induction has|dobj|roles has|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 evoked|nsubj|start_entity evoked|advcl|mimicking mimicking|dobj|effects effects|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 stimulates|nsubj|start_entity stimulates|dobj|metabolism metabolism|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 phosphorylated|advmod|start_entity phosphorylated|parataxis|phosphorylated phosphorylated|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 ability|nmod|start_entity increases|nmod|ability increases|dobj|activity activity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 models|nmod|start_entity used|nmod|models used|advcl|guided guided|nmod|results results|acl|revealing revealing|dobj|induction induction|nmod|mrna mrna|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 immunotherapy|nmod|start_entity immunotherapy|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 analgesia|amod|start_entity inhibit|dobj|analgesia inhibit|nsubj|analogs analogs|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 regulators|compound|start_entity regulators|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 2.000000 0 2.000000 0 24.000000 0 0.000000 0 9.000000 0 26.000000 0 2.000000 0 start_entity|acl|seen seen|nmod|administration administration|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 inhibit|nsubj|start_entity suggesting|ccomp|inhibit induced|advcl|suggesting shown|dep|induced shown|ccomp|blocked blocked|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effectiveness|nmod|start_entity comparison|nmod|effectiveness comparison|nmod|patients patients|nmod|mutations mutations|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 1.000000 0 7.000000 0 3.000000 0 13.000000 0 0.000000 0 1.000000 0 0.000000 0 formation|compound|start_entity affecting|dobj|formation caused|advcl|affecting caused|dobj|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 neurotransmitters|compound|start_entity breakdown|nmod|neurotransmitters catalyzes|dobj|breakdown variation|acl:relcl|catalyzes variation|nmod|gene gene|acl|encoding encoding|dobj|catechol-o-methyltransferase catechol-o-methyltransferase|appos|end_entity 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 species|compound|start_entity increased|dobj|species increased|nmod|regulation regulation|nmod|anti-apoptotic anti-apoptotic|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 produce|dobj|start_entity activating|advcl|produce activating|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 oxidoreductase|amod|start_entity included|nsubjpass|oxidoreductase included|parataxis|designated designated|xcomp|using using|xcomp|nomenclature nomenclature|nsubj|allele allele|appos|* *|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 binding|nmod|start_entity mediated|dobj|binding mediated|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 2.000000 0 5.000000 0 0.000000 0 1.000000 0 0.000000 0 infusions|nmod|start_entity measured|nmod|infusions measured|nsubjpass|pressure pressure|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 explaining|dobj|start_entity found|xcomp|explaining found|nsubjpass|variants variants|nmod|genes genes|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 increased|nmod|start_entity increased|nsubj|concentrations concentrations|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 11.000000 0 0.000000 0 treatment|amod|start_entity reduces|nsubj|treatment reduces|ccomp|induced induced|dobj|importance importance|nmod|activity activity|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 phosphatase|compound|start_entity end_entity|nsubj|phosphatase 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 30.000000 0 0.000000 0 tolerance|compound|start_entity regardless|nmod|tolerance increased|advmod|regardless increased|nsubj|responses responses|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 17.000000 0 0.000000 0 donors|amod|start_entity effects|nmod|donors due|nsubj|effects due|nmod|modification modification|nmod|groups groups|amod|present present|nmod|molecule molecule|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 dependent|nmod|start_entity dependent|nsubj|the the|nmod|effect effect|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 activators|nmod|start_entity able|nsubj|activators able|nmod|alterations alterations|acl|detected detected|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 binding|compound|start_entity transpire|nmod|binding events|acl:relcl|transpire sequence|nmod|events details|nmod|sequence obtain|dobj|details used|advcl|obtain used|dobj|analysis analysis|nmod|mutants mutants|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 similar|acl|start_entity similar|acl|induced induced|xcomp|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 killing|compound|start_entity diminish|dobj|killing diminish|nsubj|knockdown knockdown|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 cells|amod|start_entity accumulation|nmod|cells increased|dobj|accumulation increased|xcomp|overexpressing overexpressing|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 complex|nmod|start_entity resolution|nmod|complex down|nmod|resolution report|advmod|down report|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 blocked|nmod|start_entity blocked|nsubjpass|mutants mutants|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 utilization|compound|start_entity maintain|dobj|utilization gradients|xcomp|maintain caused|ccomp|gradients caused|nsubj|infusion infusion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 inhibitor|amod|start_entity orthovanadate|appos|inhibitor blocked|nmod|orthovanadate blocked|nmod|receptor receptor|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 content|amod|start_entity content|appos|activity activity|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 treatment|nmod|start_entity decreased|nsubj|treatment decreased|dobj|responses responses|acl:relcl|suggests suggests|ccomp|modulates modulates|nsubj|end_entity 2.000000 0 1.000000 0 1.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 oxidation|amod|start_entity enzymes|nmod|oxidation expression|nmod|enzymes control|nsubj|expression control|nmod|peroxisome_proliferator-activated_receptor_alpha peroxisome_proliferator-activated_receptor_alpha|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 proteins|compound|start_entity 25|dep|proteins represents|dobj|25 represents|nsubj|family family|nmod|proteins proteins|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 efficient|nmod|start_entity efficient|advcl|correcting correcting|dobj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 excess|compound|start_entity regulated|nsubjpass|excess regulated|nmod|pathway pathway|acl|involving involving|dobj|hemojuvelin hemojuvelin|acl:relcl|stimulates stimulates|dobj|expression expression|nmod|gene gene|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 efflux|amod|start_entity increased|nsubj|efflux increased|xcomp|attaining attaining|nmod|season season|nmod|day day|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 activity|amod|start_entity suppress|dobj|activity represent|advcl|suppress represent|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 oxidation|amod|start_entity mapk|dobj|oxidation mapk|nsubj|inhibitors inhibitors|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 increase|dobj|start_entity supposed|advcl|increase supposed|ccomp|decreased decreased|dobj|secretion secretion|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthesis|amod|start_entity upregulation|nmod|synthesis upregulation|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 levels|compound|start_entity had|dobj|levels had|parataxis|found found|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 binds|dobj|start_entity polypeptide|acl:relcl|binds contained|dobj|polypeptide contained|nsubj|extracts extracts|acl|enriched enriched|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 neurodegenerative_diseases|compound|start_entity reason|nmod|neurodegenerative_diseases indicated|ccomp|reason cause|parataxis|indicated cause|nsubj|elevation elevation|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 stimulation|compound|start_entity caused|nsubj|stimulation caused|dobj|exocytosis exocytosis|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 17.000000 0 0.000000 0 effect|nmod|start_entity attributed|nsubjpass|effect attributed|nmod|blockade blockade|nmod|receptors receptors|acl:relcl|activated activated|nmod|inhibitors inhibitors|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 analog|compound|start_entity stimulated|nmod|analog expression|acl|stimulated expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nsubj|children children|dep|lacked lacked|dobj|terminal_deoxynucleotidyl_transferase terminal_deoxynucleotidyl_transferase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentration|compound|start_entity decreasing|dobj|concentration stimulated|advcl|decreasing stimulated|nsubjpass|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 activity|compound|start_entity increase|nmod|activity absence|nmod|increase stores|nmod|absence depletion|nmod|stores sufficient|nsubj|depletion indicating|ccomp|sufficient procedure|acl|indicating procedure|acl|caused caused|dobj|increase increase|nmod|levels levels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 infused|dobj|start_entity infused|nmod|attempt attempt|acl|produce produce|iobj|blockade blockade|nmod|angiotensin_ii angiotensin_ii|appos|end_entity 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 amount|nmod|start_entity increased|nsubjpass|amount end_entity|dep|increased 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 increased|nsubj|start_entity increased|advcl|analyzing analyzing|dobj|change change|nmod|productions productions|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 vehicle|dep|start_entity accelerated|advcl|vehicle accelerated|nsubjpass|transit transit|nmod|administration administration|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 pretreatment|nmod|start_entity pretreatment|advcl|decreased decreased|dobj|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 transporters|compound|start_entity elucidate|nmod|transporters introduced|advcl|elucidate introduced|nmod|cdna cdna|compound|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 23.000000 0 2.000000 0 1.000000 0 concentrations|compound|start_entity reduces|dobj|concentrations reduces|advcl|decreasing decreasing|dobj|secretion secretion|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 30.000000 0 0.000000 0 markedly|amod|start_entity increased|nsubj|markedly increased|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 accumulation|compound|start_entity caused|dobj|accumulation caused|nsubj|knockdown knockdown|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 0.000000 0 metabolism|nmod|start_entity assess|nmod|metabolism assess|dobj|impact impact|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|acl:relcl|protected protected|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|compound|start_entity associated|nmod|metabolism find|ccomp|associated find|advcl|using using|dobj|genotype genotype|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 3.000000 0 0.000000 0 2.000000 0 3.000000 0 1.000000 0 doses|nmod|start_entity doubled|nmod|doses doubled|nsubjpass|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 10.000000 0 0.000000 0 0.000000 0 0.000000 0 blocked|dobj|start_entity blocked|nsubj|antagonists antagonists|nmod|receptors receptors|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 proteins|compound|start_entity sensitizes|nmod|proteins sensitizes|nsubj|accumulation accumulation|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 composition|amod|start_entity associated|nmod|composition associated|nsubjpass|genotype genotype|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 dose|nmod|start_entity diminished|nmod|dose diminished|nsubjpass|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptors|amod|start_entity ligands|nmod|receptors end_entity|nsubj|ligands 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity inhibition|nmod|effects correlated|nmod|inhibition correlated|nsubj|curve curve|nmod|protection protection|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 activity|compound|start_entity modulator|nmod|activity end_entity|appos|modulator 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 +|amod|start_entity complex|nmod|+ calmodulin|amod|complex end_entity|nmod|calmodulin 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 provoke|nsubj|start_entity provoke|nmod|inhibitors inhibitors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 using|dobj|start_entity using|nsubj|binding binding|nmod|factors factors|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|dep|induced induced|dobj|decrease decrease|nmod|level level|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 conditions|compound|start_entity cells|nmod|conditions end_entity|nmod|cells 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 effects|nmod|start_entity mitigate|dobj|effects mitigate|nmod|suppression suppression|nmod|expression expression|amod|end_entity 4.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|appos|class class|acl:relcl|ligands ligands|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|advcl|unable unable|xcomp|inhibit inhibit|dobj|growth growth|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 12.000000 0 2.000000 0 0.000000 0 6.000000 0 0.000000 0 ion|compound|start_entity ion|acl|coordinated coordinated|nmod|molecules molecules|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 efficient|nmod|start_entity end_entity|parataxis|efficient 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|amod|start_entity elevated|dobj|levels elevated|nsubj|months months|nmod|treatment treatment|nmod|doses doses|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 analysis|amod|start_entity provided|nsubj|analysis provided|parataxis|permitted permitted|nsubj|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 availability|compound|start_entity availability|dep|noted noted|nmod|decrease decrease|nmod|levels levels|amod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 transduction|compound|start_entity affect|dobj|transduction indicates|ccomp|affect vague|advcl|indicates vague|nsubj|mechanisms mechanisms|nmod|action action|acl|underlying underlying|dobj|effects effects|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 <|dobj|start_entity <|nsubj|phosphorylation phosphorylation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 channels|compound|start_entity channels|amod|intestinal intestinal|dep|secretion secretion|nmod|activation activation|nmod|regulator regulator|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 15.000000 0 3.000000 0 1.000000 0 atp7b|compound|start_entity end_entity|appos|atp7b 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 1.000000 0 0.000000 0 upregulated|nsubjpass|start_entity upregulated|advcl|unaffected unaffected|nsubj|gabar gabar|nummod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transported|nsubjpass|start_entity transported|nmod|transporter transporter|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 withdrawal|amod|start_entity observed|nmod|withdrawal observed|nsubjpass|changes changes|nmod|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 induction|nmod|start_entity apoptosis|acl|induction associated|nsubjpass|apoptosis associated|nmod|cells cells|acl:relcl|detected detected|nmod|transfectants transfectants|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 converted|dep|start_entity end_entity|xcomp|converted 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 diet|compound|start_entity elevated|nmod|diet elevated|nsubjpass|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 metabolism|compound|start_entity disorders|nmod|metabolism disorders|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 induced|nmod|start_entity moreover|dep|induced moreover|parataxis|contribute contribute|nmod|stability stability|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|compound|start_entity role|dep|uptake role|nmod|_ _|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 4.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 substrate|nsubj|start_entity substrate|nmod|inhibitor inhibitor|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptors|amod|start_entity mediate|nmod|receptors mediate|nsubj|two two|acl|cooperating cooperating|dobj|elements elements|nmod|gene gene|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 contribution|nmod|start_entity inhibition|nsubj|contribution inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 action|nmod:poss|start_entity mimicked|dobj|action mimicked|nsubj|b-naphthoflavon b-naphthoflavon|appos|aryl_hydrocarbon_receptor aryl_hydrocarbon_receptor|appos|end_entity 4.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 suppression|compound|start_entity occurred|nmod|suppression occurred|nsubj|changes changes|nmod|sensitivity sensitivity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 inactivation|nmod|start_entity involved|nmod|inactivation involved|nmod|regions regions|acl:relcl|expressed expressed|nsubj|dopamine_transporter dopamine_transporter|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 2.000000 0 agent|nsubj|start_entity agent|nmod|transplantation transplantation|acl:relcl|works works|nmod|inhibition inhibition|nmod|mammalian_target_of_rapamycin mammalian_target_of_rapamycin|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 11.000000 0 0.000000 0 2.000000 0 0.000000 0 enzymes|amod|start_entity each|nmod|enzymes increases|nmod|each increases|nsubj|potently potently|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 roles|nmod|start_entity opposing|dobj|roles hypotheses|acl|opposing test|dobj|hypotheses determined|advcl|test determined|dobj|concentrations concentrations|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 15.000000 0 0.000000 0 0.000000 0 14.000000 0 0.000000 0 signaling|compound|start_entity operate|nmod|signaling operate|nsubj|neurons neurons|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 agonists|amod|start_entity effects|nmod|agonists secretion|nmod|effects secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 patients|nmod|start_entity genotype|nmod|patients genotype|nsubj|impact impact|nmod|end_entity 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 present|nmod|start_entity vasoactive_intestinal_peptide|acl:relcl|present vasoactive_intestinal_peptide|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 found|nsubjpass|start_entity found|ccomp|inhibit inhibit|dobj|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 10.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 addition|nmod|start_entity reduced|nmod|addition reduced|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 receptor|compound|start_entity receptor|nmod|receptor receptor|nsubj|alpha alpha|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 monitoring|compound|start_entity postprandial|nmod|monitoring mellitus|nsubj|postprandial mellitus|xcomp|requiring requiring|dobj|therapy therapy|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 activators|amod|start_entity benefits|nmod|activators extend|nsubj|benefits extend|nmod|parathyroid_hormone parathyroid_hormone|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 resistance|amod|start_entity origin|nmod|resistance origin|nsubj|substitution substitution|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibition|nmod|start_entity remained|nsubj|inhibition remained|advcl|diminishing diminishing|xcomp|observed observed|nsubj|responsiveness responsiveness|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 8.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 containing|dobj|start_entity tumour|acl|containing patient|nmod|tumour peptide|amod|patient peptide|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 protects|nsubj|start_entity protects|nmod|activation activation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 substrate|appos|start_entity uptake|nmod|substrate block|dobj|uptake ability|acl|block inhibit|nmod|ability inhibit|dobj|unit unit|nmod|xc xc|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 altered|nsubjpass|start_entity stimulated|advcl|altered stimulated|dobj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 suppression|amod|start_entity prevents|dobj|suppression prevents|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 harboring|nmod|start_entity harboring|dobj|rearrangement rearrangement|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 produced|advcl|start_entity produced|nmod|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 tension|compound|start_entity exposure|nmod|tension hypoxia|amod|exposure increased|nsubj|hypoxia increased|dobj|expressions expressions|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|nmod|start_entity determined|nmod|levels determined|dobj|effects effects|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 contributed|nmod|start_entity having|ccomp|contributed glycosylated|xcomp|having glycosylated|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 production|amod|start_entity sensitive|nsubj|production sensitive|ccomp|production production|acl|illustrating illustrating|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 +|compound|start_entity increased|nsubj|+ increased|dobj|kd kd|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 plasma|nmod|start_entity incubation|nmod|plasma incubation|appos|inhibitor inhibitor|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 markers|compound|start_entity indices|appos|markers indices|nmod|saturation saturation|amod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 doses|compound|start_entity require|dobj|doses require|nsubj|genotype genotype|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 increased|nsubj|start_entity increased|dobj|cells cells|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolized|nsubjpass|start_entity metabolized|nmod|combination combination|nmod|alcohol_dehydrogenase alcohol_dehydrogenase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 start_entity|ccomp|revealed revealed|dobj|structure structure|amod|identical identical|nmod|polypeptide polypeptide|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 cpt-11|appos|start_entity 5-fluorouracil|nmod|cpt-11 chemotherapy|advcl|5-fluorouracil resistant|xcomp|chemotherapy treated|xcomp|resistant treated|nmod|aim aim|acl|reducing reducing|dobj|toxicities toxicities|nmod|irinotecan irinotecan|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pathway|amod|start_entity enzyme|nmod|pathway b|dep|enzyme as|nmod:npmod|b a|advmod|as end_entity|dep|a 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 3.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 stores|compound|start_entity emptying|dobj|stores emptying|nmod|thapsigargin thapsigargin|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 lipoprotein|amod|start_entity attenuated|nmod|lipoprotein attenuated|nmod|expression expression|nmod|receptors receptors|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 trafficking|nmod|start_entity regulates|dobj|trafficking regulates|nsubj|domain domain|nmod|protein protein|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 start_entity|dep|bk bk|dep|known known|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 disposal|compound|start_entity %|nmod|disposal %|advmod|relative relative|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 intermediate|amod|start_entity form|dobj|intermediate metabolizes|xcomp|form metabolizes|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 dehydrogenase|amod|start_entity composed|nsubjpass|dehydrogenase composed|nmod|subunits subunits|acl|encoded encoded|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 inhibition|nmod|start_entity pump|nsubj|inhibition pump|nmod|+ +|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 acted|nsubj|start_entity acted|advcl|inducing inducing|dobj|activation activation|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 reduced|nmod|start_entity reduced|nsubjpass|density density|nmod|channels channels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 oxidation|nmod|start_entity produce|nmod|oxidation produce|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 induced|nmod|start_entity level|acl|induced suppressed|nmod|level suppressed|advcl|affect affect|dobj|production production|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 level-dependent|compound|start_entity signal|nsubj|level-dependent known|ccomp|signal addition|dep|known addition|advcl|neuronal neuronal|dobj|fluctuations fluctuations|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 synthase|compound|start_entity up-regulation|nmod|synthase production|amod|up-regulation pathways|nmod|production examined|nsubjpass|pathways kinase|ccomp|examined kinase|nsubj|role role|nmod|protein protein|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 release|nmod|start_entity inhibits|dobj|release inhibits|advcl|interfering interfering|nmod|platelets platelets|acl|stimulated stimulated|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 activity|nmod:poss|start_entity inhibited|nsubjpass|activity inhibited|nmod|gonadotropin_releasing_hormone gonadotropin_releasing_hormone|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 rats|appos|start_entity rats|compound|end_entity 0.000000 0 0.000000 0 19.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 metabolism|compound|start_entity regulating|dobj|metabolism involved|advcl|regulating agonists|ccomp|involved agonists|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 intakes|amod|start_entity stores|nmod|intakes limits|nmod|stores polymorphism|advcl|limits polymorphism|nsubj|polymorphism polymorphism|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptors|compound|start_entity activated|nmod|receptors activated|nmod|influx influx|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 extracellular_signal-regulated_protein_kinase|nmod|start_entity extracellular_signal-regulated_protein_kinase|appos|end_entity 0.000000 0 1.000000 0 0.000000 0 2.000000 0 2.000000 0 5.000000 0 10.000000 0 0.000000 0 0.000000 0 0.000000 0 relevance|nmod|start_entity variants|nmod|relevance variants|acl|coding coding|nmod|transporters transporters|dep|cyp cyp|dep|_ _|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 nuclei|amod|start_entity action|nmod|nuclei releasing|dobj|action end_entity|xcomp|releasing 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity increased|nmod|treatment increased|nsubjpass|levels levels|nmod|mrna mrna|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 treatment|amod|start_entity comparable|nmod|treatment comparable|nmod|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 ratio|nmod|start_entity correlated|nmod|ratio correlated|xcomp|serum serum|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 start_entity|amod|,5 ,5|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|appos|start_entity effects|appos|inhibitor inhibitor|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|amod|start_entity +|dep|uptake increase|nmod|+ increase|dep|cells cells|acl|accompanied accompanied|nmod|increase increase|nmod|expression expression|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 12.000000 0 0.000000 0 0.000000 0 treatment|nmod|start_entity decreased|nsubj|treatment decreased|dobj|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 determination|nmod|start_entity taken|nmod|determination taken|nsubjpass|levels levels|appos|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|acl|induced induced|nmod|suppression suppression|nmod|sp1_transcription_factor sp1_transcription_factor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity similar|nmod|treatment activity|amod|similar resulting|nmod|activity levels|acl|resulting reduced|dobj|levels reduced|nsubj|overexpression overexpression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 region|compound|start_entity contains|dobj|region encodes|parataxis|contains encodes|dobj|homology homology|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 dmag|nmod|start_entity administration|acl|dmag resulted|nsubj|administration resulted|xcomp|leading leading|nmod|interactions interactions|acl:relcl|exacerbated exacerbated|nmod|mutation mutation|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 start_entity|nmod|action action|nmod|alcohol_dehydrogenase alcohol_dehydrogenase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 species|compound|start_entity reactive|dobj|species due|xcomp|reactive undergoing|xcomp|due participating|advcl|undergoing end_entity|acl|participating 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitor|appos|start_entity using|dobj|inhibitor method|acl|using assesed|nmod|method assesed|nsubjpass|activity activity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 consumption|compound|start_entity alter|dobj|consumption alter|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 use|compound|start_entity examine|dobj|use examine|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 _|appos|start_entity _|nsubj|_ _|ccomp|catalyzes catalyzes|nsubj|reductase reductase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 start_entity|advcl|undergoing undergoing|dobj|therapy therapy|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 subarachnoid_hemorrhage|appos|start_entity using|nsubj|subarachnoid_hemorrhage causes|advcl|using causes|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 hypothalamic-pituitary-adrenal_axis|dep|start_entity thyrotropin|dep|hypothalamic-pituitary-adrenal_axis hypothalamic-pituitary-thyroid_axis|nmod|thyrotropin end_entity|dep|hypothalamic-pituitary-thyroid_axis 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 pharmacokinetics|nmod|start_entity evaluate|nmod|pharmacokinetics evaluate|dobj|impact impact|nmod|polymorphisms polymorphisms|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 decreased|nsubj|start_entity conceivable|advcl|decreased conceivable|ccomp|involves involves|dobj|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 cultured|nmod|start_entity increase|advcl|cultured signaling|advcl|increase erk1/2-dependent|acl|signaling protein|nmod|erk1/2-dependent protein|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 deliver|dobj|start_entity deliver|nsubj|function function|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 activation|compound|start_entity function|nmod|activation function|nsubj|rate rate|nmod|synthesis synthesis|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 group|compound|start_entity glucose|nmod|group decreased|nmod|glucose decreased|nsubjpass|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 route|compound|start_entity side|nmod|route found|nmod|side found|nsubjpass|neurons neurons|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentrations|nmod|start_entity induce|nsubj|concentrations herein|ccomp|induce herein|dep|2 2|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 absence|nmod|start_entity regulating|nmod|absence regulating|dep|highlighting highlighting|advcl|sustain sustain|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 combining|nmod|start_entity effective|csubj|combining effective|nmod|regulation regulation|nmod|proteins proteins|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 toll-like_receptor_3|amod|start_entity toll-like_receptor_3|appos|end_entity 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 structure|amod|start_entity structure|nmod|carcinoembryonic_antigen carcinoembryonic_antigen|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 combined|nsubjpass|start_entity resulted|advcl|combined resulted|nmod|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 release|compound|start_entity stimulation|nmod|release acting|nmod|stimulation antagonist|acl|acting pirenzepine|appos|antagonist abolishes|nsubj|pirenzepine abolishes|dobj|growth_hormone_releasing_hormone growth_hormone_releasing_hormone|acl:relcl|stimulated stimulated|dobj|rise rise|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 1.000000 0 0.000000 0 9.000000 0 0.000000 0 added|nsubjpass|start_entity increase|acl:relcl|added increased|nmod|increase increased|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 phosphorylations|amod|start_entity initiate|nsubj|phosphorylations initiate|dobj|cascades cascades|nmod|docking docking|nmod|kinase kinase|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 receiving|xcomp|start_entity patients|acl|receiving determined|nmod|patients determined|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 intake|amod|start_entity increases|nsubj|intake increases|nmod|pathway pathway|nmod|cotransporter cotransporter|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 stress|compound|start_entity stimulus|appos|stress varies|advcl|stimulus varies|nsubj|mechanism mechanism|acl:relcl|evokes evokes|dobj|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 injection|nmod|start_entity purified|nmod|injection vitellogenins|acl|purified showed|nsubj|vitellogenins showed|advcl|indicating indicating|ccomp|occurs occurs|nsubj|synthesis synthesis|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 synthesis|compound|start_entity respond|nmod|synthesis respond|advcl|suggesting suggesting|ccomp|exerts exerts|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 analyses|amod|start_entity demonstrated|nsubj|analyses demonstrated|ccomp|displayed displayed|nsubj|cells cells|dep|co-expressing co-expressing|dobj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 entry|compound|start_entity voltage|dobj|entry voltage|nsubj|modulates modulates|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 levels|nmod|start_entity correlated|nsubjpass|levels correlated|nmod|levels levels|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 blocker|nsubj|start_entity blocker|acl:relcl|shown shown|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 analogue|ccomp|start_entity analogue|nsubj|cholecystokinin cholecystokinin|appos|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|amod|bound bound|dep|retinoic_acid_receptor retinoic_acid_receptor|appos|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 start_entity|appos|agent agent|acl|known known|xcomp|deplete deplete|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 3.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 catalyse|dobj|start_entity catalyse|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 excretion|nmod|start_entity route|nsubj|excretion route|nmod|inhibitors inhibitors|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 blocked|nmod|start_entity blocked|nmod|element element|nmod|promoter promoter|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 aggravated|nsubj|start_entity aggravated|dobj|decrease decrease|nmod|level level|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 10.000000 0 0.000000 0 0.000000 0 0.000000 0 profile|nmod|start_entity result|nsubj|profile result|acl|inhibitor inhibitor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 0.000000 0 duodenum|nmod|start_entity acidification|nmod|duodenum observed|nmod|acidification observed|nsubjpass|rise rise|nmod|concentration concentration|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 circulating|dobj|start_entity dependent|advcl|circulating manner|acl:relcl|dependent released|nmod|manner released|nsubjpass|gonadotropin-releasing_hormone gonadotropin-releasing_hormone|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|amod|start_entity exogenous|nmod|metabolism reversed|nmod|exogenous reversed|nsubjpass|inhibition inhibition|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 sensor|nmod|start_entity serves|nmod|sensor serves|nsubj|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 23.000000 0 2.000000 0 1.000000 0 source|nmod|start_entity placenta|nmod|source regulates|nsubj|placenta regulates|nmod|receptor receptor|appos|end_entity 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 3.000000 0 0.000000 0 6.000000 0 synthesis|amod|start_entity varies|nsubj|synthesis end_entity|advcl|varies 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transmission|compound|start_entity affected|nsubjpass|transmission ipscs|dep|affected controlling|dobj|ipscs restricted|xcomp|controlling restricted|nsubjpass|effect effect|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 using|dobj|start_entity blocking|advcl|using end_entity|acl|blocking 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 11.000000 0 0.000000 0 0.000000 0 0.000000 0 transferrin|compound|start_entity that|nmod|transferrin undertaken|nmod|that undertaken|xcomp|assess assess|dobj|role role|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 signalling|compound|start_entity regulator|nmod|signalling expression|appos|regulator down-regulated|nsubj|expression oxidases|advcl|down-regulated up-regulated|ccomp|oxidases up-regulated|nsubj|overexpression overexpression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptors|compound|start_entity relationship|nmod|receptors has|dobj|relationship has|nsubj|neuronal_nos neuronal_nos|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 blockers|compound|start_entity recommended|nmod|blockers recommended|parataxis|blocking blocking|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibit|nsubj|start_entity inhibited|advcl|inhibit inhibited|dobj|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 hormone|advmod|start_entity hormone|nsubj|glucagon-like_peptide-1 glucagon-like_peptide-1|appos|end_entity 1.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 monocyte_chemoattractant_protein-1|amod|start_entity driven|nmod|monocyte_chemoattractant_protein-1 infiltration|acl|driven infiltration|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2,3,7,8-tetrachlorodibenzo-p-dioxin|dep|start_entity treatment|amod|2,3,7,8-tetrachlorodibenzo-p-dioxin had|nsubj|treatment had|dobj|effects effects|nmod|target target|nmod|signaling signaling|compound|end_entity 4.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 oxidase|compound|start_entity amount|nmod|oxidase amount|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 infusion|compound|start_entity had|nsubj|infusion had|nmod|concentration concentration|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|nmod|type type|amod|end_entity 0.000000 0 3.000000 0 0.000000 0 0.000000 0 2.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 transporter|compound|start_entity expression|nmod|transporter ameliorated_insulin_sensitivity_of_skeletal_muscle|nmod|expression ameliorated_insulin_sensitivity_of_skeletal_muscle|nsubj|deficiency deficiency|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 0.000000 0 2.000000 0 2.000000 0 0.000000 0 glucuronidation|compound|start_entity inhibitor|nmod|glucuronidation inhibitor|nsubj|substrate substrate|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 2.000000 0 1.000000 0 activity|amod|start_entity elevation|nmod|activity accompanied|nsubj|elevation accompanied|advcl|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 serotonin|appos|start_entity remove|dobj|serotonin remove|nsubj|role role|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 works|nsubj|start_entity works|advcl|binding binding|dep|preventing preventing|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|acl|associated associated|nmod|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 30.000000 0 0.000000 0 demethylase|compound|start_entity activity|nmod|demethylase resulted|nmod|activity resulted|nsubj|pretreatment pretreatment|nmod|rats rats|appos|inducer inducer|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|amod|start_entity requirement|nmod|metabolism requirement|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|amod|start_entity reduction|nmod|levels reduction|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 self-administration|compound|start_entity -rsb-|compound|self-administration days|nmod|-rsb- average|nmod|days peaked|nmod|average peaked|nsubj|increases increases|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|appos|inhibitor inhibitor|nmod|protein_tyrosine_phosphatases protein_tyrosine_phosphatases|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 bind|dobj|start_entity isomerases|acl:relcl|bind isomerases|nsubj|proteins proteins|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 homeostasis|compound|start_entity translation|nmod|homeostasis translation|nsubj|role role|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 analysed|nmod|start_entity analysed|nsubjpass|dosage dosage|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 pharmacokinetics|nmod|start_entity zixoryn|nmod|pharmacokinetics zixoryn|appos|inductor inductor|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 affect|nsubj|start_entity affect|nmod|pvn pvn|nmod|binding binding|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 mimetic|compound|start_entity mimetic|acl:relcl|targets targets|dobj|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 consumption|compound|start_entity induced|nmod|consumption cardiac_remodeling|dep|induced involved|advcl|cardiac_remodeling involved|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 presence|nmod|start_entity induced|nmod|presence decreased|advcl|induced decreased|ccomp|decreased decreased|nsubjpass|activity activity|acl:relcl|increased increased|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|compound|start_entity view|nmod|metabolism changed|dobj|view changed|nsubj|discovery discovery|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 11.000000 0 0.000000 0 4.000000 0 12.000000 0 1.000000 0 compounds|nmod|start_entity metabolism|nmod|compounds role|nmod|metabolism plays|dobj|role plays|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 sensitizes|xcomp|start_entity sensitizes|nsubj|silencing silencing|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|compound|start_entity influence|dobj|metabolism influence|nsubj|analogs analogs|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 reduction|compound|start_entity responsible|nmod|reduction responsible|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitors|amod|start_entity inhibitors|acl:relcl|rescue rescue|dobj|failures failures|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 substituted|nsubjpass|start_entity synthesis|acl:relcl|substituted synthesis|nmod|insulin insulin|dep|gly2 gly2|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 capsaicin|compound|start_entity associated|nmod|capsaicin drugs|acl|associated injection|nmod|drugs examined|nmod|injection examined|dobj|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 independent|compound|start_entity independent|nmod|concentration concentration|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 induction|nmod|start_entity apoptosis|acl|induction investigated|nmod|apoptosis investigated|dobj|activation activation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 decreases|nsubj|start_entity decreases|dobj|currents currents|nmod|neurons neurons|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 elevated|nsubj|start_entity elevated|parataxis|abolished abolished|xcomp|suggesting suggesting|dobj|control control|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitors|compound|start_entity cohorts|nmod|inhibitors cohorts|nmod|those those|acl|harboring harboring|dobj|mutations mutations|nmod|end_entity 0.000000 0 0.000000 0 7.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 cells|compound|start_entity control|appos|cells that|nmod|control lower|nmod|that treated|ccomp|lower treated|nsubj|level level|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 added|advcl|start_entity added|nsubj|discovery discovery|appos|end_entity 2.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 8.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 gavaged|nmod|start_entity gavaged|nsubjpass|group group|compound|end_entity 0.000000 0 4.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 receptor|compound|start_entity complex|nsubj|receptor complex|nmod|subunit subunit|compound|end_entity 0.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 mediating|nmod|start_entity step|acl|mediating step|nsubj|interaction interaction|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 responses|compound|start_entity mediate|dobj|responses reported|xcomp|mediate receptor|acl|reported receptor|nsubj|g_protein-coupled_estrogen_receptor g_protein-coupled_estrogen_receptor|appos|end_entity 1.000000 0 0.000000 0 6.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 addition|nmod|start_entity treated|nsubj|addition treated|ccomp|sufficient sufficient|xcomp|activate activate|xcomp|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 rose|nmod|start_entity rose|nsubj|levels levels|compound|end_entity 0.000000 0 1.000000 0 2.000000 0 1.000000 0 0.000000 0 39.000000 0 1.000000 0 3.000000 0 61.000000 0 0.000000 0 mediated|nmod|start_entity mediated|nsubjpass|effects effects|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 affects|nsubj|start_entity affects|nmod|activation activation|nmod|peroxisome_proliferator-activated_receptor_alpha peroxisome_proliferator-activated_receptor_alpha|appos|end_entity 4.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 mobilize|dobj|start_entity mobilize|nmod|liver liver|acl|suppressing suppressing|dobj|mrna mrna|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 substrate|nsubj|start_entity oxidise|advcl|substrate oxidise|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 mg/day|amod|start_entity stabilization|nmod|mg/day 118|nmod|stabilization 128|parataxis|118 128|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|appos|inhibitor inhibitor|amod|epidermal_growth_factor_receptor epidermal_growth_factor_receptor|dep|end_entity 0.000000 0 2.000000 0 0.000000 0 1.000000 0 12.000000 0 8.000000 0 25.000000 0 1.000000 0 1.000000 0 0.000000 0 mg|dobj|start_entity mg|nsubj|characteristics characteristics|nmod|patients patients|nmod|refractory refractory|nmod|inhibitors inhibitors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 attenuated|nmod|start_entity attenuated|xcomp|indicating indicating|dobj|function function|nmod|channels channels|amod|end_entity 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 isoform|nmod|start_entity end_entity|appos|isoform 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 improved|dep|start_entity improved|nsubj|decarboxylase decarboxylase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 secretion|amod|start_entity inhibition|nmod|secretion require|nsubj|inhibition require|advcl|shown shown|ccomp|cosmetic cosmetic|nsubj|reduction reduction|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 treatment|compound|start_entity vivo|nmod|treatment obtained|dobj|vivo data|acl|obtained data|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 interaction|nmod|start_entity leads|nsubj|interaction leads|nmod|change change|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 release|nmod|start_entity resulted|nmod|release resulted|nmod|gradient gradient|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 levels|compound|start_entity lower|dobj|levels lower|nsubj|incretins incretins|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|amod|inducible inducible|dep|end_entity 0.000000 0 2.000000 0 0.000000 0 0.000000 0 3.000000 0 4.000000 0 15.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|acl:relcl|overexpressed overexpressed|nsubjpass|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 effective|nsubj|start_entity effective|ccomp|established established|ccomp|inhibitors inhibitors|nsubj|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 7.000000 0 8.000000 0 16.000000 0 1.000000 0 5.000000 0 0.000000 0 used|nsubjpass|start_entity used|advcl|determine determine|ccomp|contribute contribute|nsubj|induction induction|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 7.000000 0 8.000000 0 16.000000 0 1.000000 0 5.000000 0 0.000000 0 up-regulate|nsubj|start_entity up-regulate|nmod|inhibition inhibition|nmod|hdac1/2 hdac1/2|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptors|amod|start_entity efficacy|nmod|receptors possession|nmod|efficacy requirement|nsubj|possession requirement|nmod|induction induction|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 feeding|nummod|start_entity implicated|nmod|feeding receptors|acl|implicated receptors|nummod|end_entity 2.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 abolished|nmod|start_entity abolished|nsubjpass|stimulation stimulation|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 patients|nmod|start_entity associated|nmod|patients associated|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 administration|nmod|start_entity enhance|nsubj|administration enhance|advcl|modifying modifying|dobj|level level|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 3.000000 0 0.000000 0 1.000000 0 0.000000 0 indicate|ccomp|start_entity expressed|ccomp|indicate expressed|nsubjpass|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 hydrolysis|compound|start_entity catalyzes|dobj|hydrolysis catalyzes|advcl|drive drive|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 content|amod|start_entity content|acl|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 mediates|nummod|start_entity that|dep|mediates demonstrated|dep|that demonstrated|nmod|experiments experiments|acl|showing showing|ccomp|increased increased|advcl|reducing reducing|dobj|protein protein|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 treatment|compound|start_entity promoter|nmod|treatment decreased|nmod|promoter decreased|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 prevents|nsubj|start_entity prevents|ccomp|mediating mediating|nsubj|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 agonist|appos|start_entity suggesting|nsubj|agonist noxious|advcl|suggesting noxious|nsubj|activity activity|nmod|end_entity 3.000000 0 0.000000 0 10.000000 0 1.000000 0 0.000000 0 4.000000 0 1.000000 0 3.000000 0 1.000000 0 0.000000 0 n-0164|compound|start_entity blocks|nsubj|n-0164 blocks|dobj|actions actions|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 excursion|compound|start_entity lowered|dobj|excursion lowered|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 represents|nsubj|start_entity represents|advcl|due due|nmod|combination combination|nmod|activity activity|amod|binding binding|nmod|end_entity 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 phorbol_12-myristate_13-acetate|appos|start_entity expression|nmod|phorbol_12-myristate_13-acetate expression|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 z-lehd-fluoromethyl_ketone|dep|start_entity z-lehd-fluoromethyl_ketone|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 ltp|compound|start_entity ltp|nmod|area area|compound|end_entity 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 release|nmod|start_entity results|nmod|release activation|acl:relcl|results activation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 uptake|amod|start_entity regulation|nmod|uptake implications|nmod|regulation modifications|dep|implications modifications|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 stimulates|nsubj|start_entity stimulates|nmod|islets islets|nmod|amplification amplification|nmod|mass mass|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 component|compound|start_entity component|appos|end_entity 0.000000 0 0.000000 0 17.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 1.000000 0 myocardial_damage|compound|start_entity examined|nmod|myocardial_damage examined|nmod|overexpression overexpression|nmod|aldehyde_dehydrogenase-2 aldehyde_dehydrogenase-2|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 increased|nsubj|start_entity increased|dobj|cmax cmax|nmod|concentration concentration|nmod|manner manner|amod|repaglinide repaglinide|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pump|compound|start_entity characterization|nmod|pump characterization|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 2.000000 0 sufficiency|amod|start_entity achieving|dobj|sufficiency achieving|nmod|day day|acl|having having|dobj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 resulted|nmod|start_entity resulted|nsubj|inhibition inhibition|nmod|end_entity 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 related|nmod|start_entity related|nmod|resistance resistance|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 symptoms|compound|start_entity measures|nmod|symptoms using|nsubj|measures report|advcl|using report|dobj|association association|nmod|variants variants|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 supply|compound|start_entity result|nmod|supply increased|nmod|result increased|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 release|amod|start_entity stimulation|nmod|release seen|nsubjpass|stimulation concentration|acl:relcl|seen concentration|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 pathways|amod|start_entity deregulation|nmod|pathways provide|nmod|deregulation provide|csubj|targeting targeting|xcomp|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 limit|nsubj|start_entity lower|advcl|limit lower|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 intolerant|nmod|start_entity used|nmod|intolerant used|nsubjpass|agonists agonists|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 involved|nmod|start_entity residues|acl|involved elucidate|dobj|residues determined|advcl|elucidate determined|nsubjpass|structures structures|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 stimulation|amod|start_entity leads|nsubj|stimulation leads|nmod|phosphorylation phosphorylation|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 levels|amod|start_entity increase|nmod|levels induced|dobj|increase infusion|acl|induced infusion|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 levels|nmod|start_entity levels|dep|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 that|nmod|start_entity that|nsubj|number number|nmod|granules granules|acl|associated associated|nmod|receptor receptor|compound|end_entity 0.000000 0 0.000000 0 19.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 confirmed|nmod|start_entity confirmed|nsubj|analysis analysis|nmod|fibroblasts fibroblasts|acl|lacking lacking|dobj|p53 p53|nmod|homozygous homozygous|appos|+ +|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthesis|amod|start_entity enzyme|nmod|synthesis activity|nmod|enzyme activity|dep|ornithine_decarboxylase ornithine_decarboxylase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 concentrations|compound|start_entity studies|nmod|concentrations mg/l|nsubj|studies mg/l|advcl|identify identify|dobj|alleles alleles|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 mg|compound|start_entity -rsb-|nmod|mg addition|dep|-rsb- addition|nmod|micrograms micrograms|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 oxidase|compound|start_entity inhibition|nmod|oxidase inhibition|amod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 tumorigenicity|nmod|start_entity contribute|nmod|tumorigenicity contribute|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|compound|start_entity reduction|nmod|uptake associated|nsubjpass|reduction associated|nmod|phosphorylation phosphorylation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 3.000000 0 5.000000 0 0.000000 0 levels|nmod|start_entity maintained|nmod|levels maintained|nsubjpass|transcription transcription|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 site|compound|start_entity close|nsubj|site suggesting|ccomp|close 2-fold|xcomp|suggesting 2-fold|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 cells|nmod|start_entity resulted|nsubj|cells resulted|nmod|activation activation|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 access|nmod:poss|start_entity interfere|nmod|access interfere|xcomp|implicating implicating|dobj|presence presence|nmod|compounds compounds|nmod|site site|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 depicted|nmod|start_entity conditions|acl|depicted oxidative|dobj|conditions oxidative|nmod|induction induction|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 carboxylase|acl|start_entity increased|nmod|carboxylase increased|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 receptor|compound|start_entity cdnas|compound|receptor cloned|nsubjpass|cdnas cloned|nmod|clone clone|acl|encoding encoding|dobj|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 channel|compound|start_entity role|nmod|channel study|dobj|role vanilloid|dep|study vanilloid|dobj|type type|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 2.000000 0 0.000000 0 analogue|compound|start_entity beraprost|appos|analogue inhibited|nsubj|beraprost inhibited|dobj|angiotensin_ii angiotensin_ii|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|nmod|action action|nmod|luteinizing_hormone-releasing_hormone luteinizing_hormone-releasing_hormone|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 reabsorption|amod|start_entity action|nmod|reabsorption mechanism|nmod|action have|dobj|mechanism have|nsubj|inhibitors inhibitors|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 8.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 gamma-amino_butyric_acid|appos|start_entity gamma-amino_butyric_acid|acl:relcl|produces produces|advcl|inhibiting inhibiting|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity responded|nmod|treatment all|acl:relcl|responded greater|nmod|all greater|nsubj|concentrations concentrations|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 retinyl_ester|compound|start_entity unesterified|dobj|retinyl_ester unesterified|nsubjpass|much much|nmod|milk milk|amod|retinoid retinoid|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 fixation|compound|start_entity participating|nmod|fixation grow|parataxis|participating grow|parataxis|convert convert|dobj|amounts amounts|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 absence|nmod|start_entity binding|nmod|absence concentration|amod|binding concentration|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 phosphorylation|compound|start_entity rate|nmod|phosphorylation decreasing|dobj|rate interact|advcl|decreasing suggests|ccomp|interact suggests|nsubj|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 given|xcomp|start_entity given|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 added|xcomp|start_entity efficacy|ccomp|added efficacy|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 esterification|compound|start_entity stimulate|dobj|esterification stimulate|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 responses|nmod|start_entity account|nmod|responses account|nsubj|differences differences|appos|estrogen_receptor estrogen_receptor|appos|end_entity 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 removal|nmod|start_entity function|nmod|removal function|ccomp|suggest suggest|ccomp|antagonistic antagonistic|advcl|does does|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 inhibitor|appos|start_entity did|nsubj|inhibitor did|ccomp|also also|nsubj|increase increase|nmod|phosphorylation phosphorylation|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 1.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 increases|nsubj|start_entity increases|dep|not not|dep|known known|ccomp|involved involved|nsubjpass|g_protein-coupled_estrogen_receptor g_protein-coupled_estrogen_receptor|appos|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 depletion|amod|start_entity express|nmod|depletion number|acl:relcl|express number|nmod|neurons neurons|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 concentration|compound|start_entity controls|dobj|concentration controls|nsubj|+ +|dep|sensing_receptor sensing_receptor|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 reducing|dobj|start_entity capable|advcl|reducing capable|nsubj|ribozyme ribozyme|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 oxidase|compound|start_entity susceptibility|nmod|oxidase indicated|nmod|susceptibility has|advcl|indicated has|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 correlated|nsubjpass|start_entity exhibited|advcl|correlated exhibited|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 stimulation|nmod|start_entity led|nsubj|stimulation led|nmod|expression expression|acl:relcl|sensitive sensitive|nmod|sb203580 sb203580|amod|end_entity 3.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|acl|suggesting suggesting|ccomp|require require|nsubj|movement movement|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 pulse|compound|start_entity peak|appos|pulse peak|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 dehydroepiandrosterone|appos|start_entity known|nsubjpass|dehydroepiandrosterone known|nmod|inhibitor inhibitor|nmod|glucose-6-phosphate_dehydrogenase glucose-6-phosphate_dehydrogenase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 response|nmod|start_entity economics|nmod|response caused|nmod|economics caused|csubj|rising rising|dobj|concentration concentration|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 receptor|amod|start_entity receptor|nsubj|macrophage_colony-stimulating_factor-1_receptor macrophage_colony-stimulating_factor-1_receptor|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 release|compound|start_entity role|nmod|release plays|dobj|role plays|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 inhibited|nsubj|start_entity inhibitor|ccomp|inhibited inhibitor|nsubj|mitogen-activated_protein_kinase_kinase mitogen-activated_protein_kinase_kinase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 2.000000 0 24.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|compound|start_entity regulator|nmod|metabolism act|nmod|regulator adipocytes|acl:relcl|act secreted|nmod|adipocytes peptide|acl|secreted peptide|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 13.000000 0 0.000000 0 24s-hydroxylase|compound|start_entity 24s-hydroxylase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 5.000000 0 0.000000 0 metabolizing|xcomp|start_entity removes|advcl|metabolizing removes|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 formation|compound|start_entity activity|nmod|formation activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibition|nmod|start_entity hydrolysis|nsubj|inhibition hydrolysis|nmod|attenuates_pain attenuates_pain|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 homeostasis|compound|start_entity blockade|nmod|homeostasis blockade|nmod|blockade blockade|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 rgcs|compound|start_entity associated|nmod|rgcs associated|nmod|level level|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effectiveness|nmod|start_entity level|nmod|effectiveness result|nmod|level result|advcl|altering altering|dobj|levels levels|compound|end_entity 0.000000 0 4.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity mediated|nsubjpass|effect mediated|nmod|enhancement enhancement|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 shock|amod|start_entity role|nmod|shock have|dobj|role have|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transporters|compound|start_entity encoding|dobj|transporters encoding|advcl|inhibiting inhibiting|dobj|function function|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nsubj|relation relation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 induced|advcl|start_entity induced|acl|induced induced|nmod|production production|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 abolished|nsubj|start_entity function|dep|abolished function|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 8.000000 0 18.000000 0 2.000000 0 2.000000 0 1.000000 0 prostaglandins|nmod|start_entity production|nmod|prostaglandins catalyse|dobj|production catalyse|nsubj|enzymes enzymes|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 channel|compound|start_entity indicated|nsubj|channel indicated|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 15.000000 0 3.000000 0 1.000000 0 start_entity|compound|cholesterol levels|nmod|cholesterol methods|dep|levels methods|nmod|cells cells|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 accumulation|compound|start_entity reduced|nmod|accumulation reduced|nsubj|pre-treatment pre-treatment|nmod|microglia microglia|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 blocked|nmod|start_entity blocked|xcomp|indicating indicating|ccomp|mediated mediated|nmod|autoreceptor autoreceptor|nummod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 injection|nmod|start_entity produced|nsubj|injection intravenous|advcl|produced intravenous|nmod|concentration concentration|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 9cra|amod|start_entity retinoid|dep|9cra activator|amod|retinoid activator|appos|end_entity 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitors|compound|start_entity predicting|nmod|inhibitors important|advcl|predicting important|nsubj|analysis analysis|nmod|mutations mutations|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 exposure|nmod|start_entity influence|nsubj|exposure influence|dobj|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 gained|nsubj|start_entity gained|xcomp|following following|dobj|review review|appos|+ +|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 dismutase|amod|start_entity showed|nsubj|dismutase showed|advcl|increased increased|nsubjpass|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 influenced|nmod|start_entity influenced|xcomp|genes genes|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 exhibit|compound|start_entity cholesteryl_ester_transfer_protein|dep|exhibit cholesteryl_ester_transfer_protein|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 production|nmod|start_entity catalyzes|dobj|production end_entity|acl:relcl|catalyzes 0.000000 0 0.000000 0 2.000000 0 0.000000 0 6.000000 0 13.000000 0 2.000000 0 5.000000 0 6.000000 0 12.000000 0 <|amod|start_entity 80|dep|< 80|dep|> >|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nmod|concentrations concentrations|acl:relcl|inhibit inhibit|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 11.000000 0 0.000000 0 0.000000 0 0.000000 0 channels|compound|start_entity role|nmod|channels investigate|dobj|role investigate|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 cassette|compound|start_entity inhibition|nmod|cassette showing|dobj|inhibition identified|xcomp|showing identified|nsubjpass|class class|nmod|inhibitors inhibitors|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 metformin|appos|start_entity dependence|dep|metformin dependence|nmod|agonists agonists|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 switched|nmod|start_entity imatinib|acl:relcl|switched frontline|dobj|imatinib performed|advcl|frontline performed|dobj|analysis analysis|nmod|transcripts transcripts|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 cardiomyopathy|compound|start_entity detrimental|nmod|cardiomyopathy detrimental|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 efflux|compound|start_entity mediates|dobj|efflux end_entity|acl:relcl|mediates 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 20.000000 0 6.000000 0 0.000000 0 administered|nsubjpass|start_entity administered|ccomp|controlled controlled|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 leading|nmod|start_entity muscle|dep|leading program|nmod|muscle triggers|dobj|program triggers|nsubj|subtype subtype|appos|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 depletion|compound|start_entity er|dobj|depletion er|nsubj|oligomerization oligomerization|nmod|couples couples|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 present|nsubj|start_entity present|nmod|somnifera somnifera|acl:relcl|shown shown|nmod|protein protein|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 deprivation|compound|start_entity associated|nsubjpass|deprivation associated|advcl|associated associated|nsubjpass|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pathway|amod|start_entity enzyme|nmod|pathway agent|appos|enzyme agent|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 test|compound|start_entity assessed|nmod|test assessed|dobj|level level|appos|level level|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 start_entity|appos|dehydroepiandrosterone-sulphate dehydroepiandrosterone-sulphate|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentrations|compound|start_entity increase|dobj|concentrations sufficient|xcomp|increase dose|amod|sufficient precursor|nmod|dose administration|nmod|precursor had|nsubj|administration had|dobj|effect effect|nmod|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 effects|nmod|start_entity explanation|nmod|effects kinase|acl:relcl|explanation kinase|amod|end_entity 0.000000 0 2.000000 0 0.000000 0 1.000000 0 4.000000 0 4.000000 0 10.000000 0 0.000000 0 0.000000 0 0.000000 0 calmodulin-dependent_kinase_iv|compound|start_entity calmodulin-dependent_kinase_iv|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 start_entity|nsubj|study study|nmod|blocker blocker|amod|end_entity 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 species|compound|start_entity caused|nmod|species protein|acl|caused modification|nmod|protein determined|nmod|modification determined|nsubjpass|increase increase|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 preconstricted|nmod|start_entity preconstricted|nsubj|doses doses|nmod|vasodilations vasodilations|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 caused|nmod|start_entity breaks|acl|caused reversed|dobj|breaks reversed|nsubj|overexpression overexpression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 oxidation|amod|start_entity responsible|nmod|oxidation isozymes|amod|responsible isozymes|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 metabolism|compound|start_entity regulators|nmod|metabolism one|nmod|regulators end_entity|appos|one 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 11.000000 0 0.000000 0 4.000000 0 12.000000 0 1.000000 0 ability|nmod|start_entity indicating|dobj|ability group|acl|indicating decreased|nmod|group decreased|nsubjpass|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptor|nmod|start_entity forms|nsubj|receptor forms|dobj|complex complex|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibits|nsubj|start_entity suggesting|ccomp|inhibits suppressed|xcomp|suggesting suppressed|nmod|plcs plcs|nmod|mice mice|amod|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 2.000000 0 receptor|compound|start_entity analysis|acl:relcl|receptor analysis|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 start_entity|acl|resulted resulted|nmod|phosphorylation phosphorylation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 therapy|amod|start_entity addition|nmod|therapy achieve|nsubj|addition achieve|nmod|acceleration acceleration|nmod|system system|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 pyrrolidine_dithiocarbamate|appos|start_entity stimulated|nmod|pyrrolidine_dithiocarbamate stimulated|advcl|investigate investigate|dobj|effect effect|nmod|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 administration|nmod|start_entity administration|appos|inhibitor inhibitor|nmod|i i|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 iv|nsubj|start_entity iv|dep|induced induced|dobj|increase increase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 increase|dobj|start_entity increase|nmod|phospholipase_a2 phospholipase_a2|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 levels|compound|start_entity increase|nmod|levels resulting|nmod|increase provide|xcomp|resulting provide|ccomp|cyclase cyclase|nsubj|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 fibroblasts|nmod|start_entity preincubation|nmod|fibroblasts preincubation|appos|inhibitor inhibitor|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 7.000000 0 8.000000 0 16.000000 0 1.000000 0 5.000000 0 0.000000 0 secretion|compound|start_entity changes|nmod|secretion led|nmod|changes led|nmod|induction induction|nmod|excretion excretion|dep|3.4-fold 3.4-fold|nmod|mice mice|amod|wild-types wild-types|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 exposure|compound|start_entity days|dep|exposure reversed|nmod|days prevented|advcl|reversed prevented|advcl|replenished replenished|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 gradient|compound|start_entity gradient|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 10.000000 0 0.000000 0 1.000000 0 18.000000 0 0.000000 0 hyperglycemia|amod|start_entity due|nsubj|hyperglycemia due|nmod|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 membrane|nmod|start_entity disruption|nmod|membrane dissociates|nsubj|disruption dissociates|advcl|suggesting suggesting|dobj|interact interact|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|dep|solutions solutions|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibited|xcomp|start_entity inhibited|advcl|inhibited inhibited|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 ctcf|compound|start_entity sites|nmod|ctcf presence|nmod|sites presence|acl|raising raising|ccomp|sufficient sufficient|nsubj|binding binding|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 presence|nmod|start_entity particularly|nmod|presence glucuronosyltransferase|advmod|particularly glucuronosyltransferase|dobj|1a1 1a1|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 level|nummod|start_entity determining|dobj|level pivotal|advcl|determining autoreceptor-mediated|ccomp|pivotal autoreceptor-mediated|nsubj|5-ht 5-ht|nmod|end_entity 1.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effects|amod|start_entity identify|dobj|effects identify|nsubj|mutation mutation|acl:relcl|preserves preserves|dobj|% %|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 3.000000 0 effects|nmod|start_entity investigate|dobj|effects was|xcomp|investigate was|advcl|represent represent|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibition|appos|start_entity induced|nsubj|inhibition induced|nmod|stimulation stimulation|nmod|autoreceptors autoreceptors|nummod|end_entity 1.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 impair|dobj|start_entity impair|nsubj|defects defects|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentration|nmod|start_entity varied|nmod|concentration varied|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 channel|compound|start_entity voltage-gated|dobj|channel end_entity|acl:relcl|voltage-gated 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 catabolism|nmod|start_entity became|nmod|catabolism became|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 production|nmod|start_entity induced|nsubj|production induced|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 7.000000 0 0.000000 0 0.000000 0 5.000000 0 1.000000 0 channel|compound|start_entity channel|nmod|reticulum reticulum|appos|ryanodine_receptor ryanodine_receptor|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 kinases|compound|start_entity family|nmod|kinases comprise|nsubj|family comprise|parataxis|end_entity 0.000000 0 0.000000 0 7.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 presence|nmod|start_entity became|nmod|presence became|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 exposure|compound|start_entity increased|nsubj|exposure increased|ccomp|enzyme enzyme|nmod|increase increase|nmod|protein protein|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|advcl|up-regulating up-regulating|dobj|expressions expressions|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 membrane|nmod|start_entity translocation|nmod|membrane measured|nsubj|translocation measured|parataxis|observed observed|nmod|phosphorylation phosphorylation|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 monolayers|nmod|start_entity treatment|nmod|monolayers caused|nsubj|treatment caused|nmod|accumulation accumulation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 administration|nmod|start_entity evaluated|nsubjpass|administration serum|advcl|evaluated serum|dobj|levels levels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 treatment|compound|start_entity reduced|nsubj|treatment reduced|xcomp|circulating circulating|dobj|concentrations concentrations|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|amod|start_entity alter|dobj|metabolism alter|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 10.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 effect|nmod|start_entity led|nsubj|effect led|nmod|surge surge|nmod|search search|nmod|antagonists antagonists|compound|end_entity 3.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 formation|amod|start_entity stimulation|nmod|formation activation|appos|stimulation activation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 play|nmod|start_entity play|nsubj|et-3 et-3|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 d,l-fenfluramine|nummod|start_entity dose|nmod|d,l-fenfluramine response|nmod|dose response|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 control|compound|start_entity levels|nmod|control management|nmod|levels compared|nmod|management myocardial_infarction|dep|compared patients|nmod|myocardial_infarction improves|nmod|patients improves|nsubj|treatment treatment|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 catalase|amod|start_entity catalase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 bind|amod|start_entity bind|nmod|region region|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 pretreatment|nmod|start_entity inhibited|nsubj|pretreatment inhibited|dobj|activation activation|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitor|compound|start_entity inhibitor|acl:relcl|demonstrated demonstrated|nmod|bc bc|dep|bc bc|dep|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 levels|amod|start_entity related|nsubjpass|levels normal|advcl|related normal|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 suppresses|nsubj|start_entity suppresses|nmod|downregulation downregulation|nmod|skp2 skp2|nmod|accumulation accumulation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 hydroxylated|dobj|start_entity hydroxylated|advcl|hydroxylated hydroxylated|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 enzyme|nmod|start_entity known|xcomp|enzyme identified|parataxis|known identified|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 influx|compound|start_entity mediated|nmod|influx mediated|nsubjpass|appearance appearance|nmod|increase increase|nmod|levels levels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity achieved|nsubjpass|effect achieved|advcl|decreasing decreasing|dobj|secretion secretion|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 4.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 transporter|compound|start_entity and/or|dobj|transporter and/or|nsubj|release release|nmod|cells cells|amod|modified modified|xcomp|express express|dobj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity levels|appos|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 concentration|nmod|start_entity stress|dep|concentration evaluation|nmod|stress measured|nsubjpass|evaluation measured|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 inhibitor|amod|start_entity azd8931|appos|inhibitor azd8931|appos|end_entity 0.000000 0 0.000000 0 7.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 uptake|compound|start_entity increases|dobj|uptake ph.|ccomp|increases media|acl:relcl|ph. changes|nmod|media regulated|nmod|changes regulated|nsubjpass|abundance abundance|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 levels|nmod|start_entity had|dobj|levels had|nmod|men men|dep|cholesterol cholesterol|dep|g/l g/l|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 levels|compound|start_entity decreased|nsubjpass|levels higher|advcl|decreased higher|nsubj|expression expression|compound|end_entity 0.000000 0 0.000000 0 19.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 blocked|nsubj|start_entity blocked|advcl|indicating indicating|dobj|transactivation transactivation|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 5.000000 0 12.000000 0 1.000000 0 0.000000 0 0.000000 0 presence|nmod|start_entity inhibited|nmod|presence inhibited|dobj|uptake uptake|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 toxicity|compound|start_entity endpoints|nmod|toxicity endpoints|nsubj|mediates mediates|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 hydrolysis|compound|start_entity stabilized|nmod|hydrolysis associated|advcl|stabilized favor|ccomp|associated favor|nmod|case case|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 ethidium_bromide|dep|start_entity ethidium_bromide|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 homeostasis|compound|start_entity facets|nmod|homeostasis regulating|dobj|facets discuss|advcl|regulating discuss|dobj|evidence evidence|nmod|system system|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 17.000000 0 0.000000 0 gsh-px|dep|start_entity peroxidase|dep|gsh-px coisolated|nsubjpass|peroxidase coisolated|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 affects|nmod|start_entity affects|advcl|evaluating evaluating|dobj|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 received|xcomp|start_entity received|nmod|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 increased|nsubj|start_entity increased|advcl|caused caused|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 10.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 gfap|acl|start_entity response|nmod|gfap suggests|nsubj|response suggests|ccomp|have have|dobj|effects effects|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 synthesis|amod|start_entity inhibition|nmod|synthesis background|dep|inhibition background|dep|products products|nmod|klothob klothob|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitor|dep|start_entity inhibitor|nsubj|administration administration|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 11.000000 0 0.000000 0 2.000000 0 0.000000 0 effects|amod|start_entity block|dobj|effects block|nmod|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 removed|nsubjpass|start_entity removed|nmod|substrates substrates|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 region|compound|start_entity region|nmod|end_entity 1.000000 0 0.000000 0 42.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 18.000000 0 2.000000 0 0.000000 0 efflux|compound|start_entity promote|dobj|efflux end_entity|acl|promote 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 start_entity|nsubj|study study|nmod|messenger messenger|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 chemotherapy|appos|start_entity safety|nmod|chemotherapy evaluated|dobj|safety evaluated|advcl|has has|nsubj|blockade blockade|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentration|compound|start_entity control|nmod|concentration contribute|xcomp|control proteins|acl:relcl|contribute regulation|nmod|proteins plays|nmod|regulation plays|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 suppressed|nsubj|start_entity increased|advcl|suppressed increased|nsubj|activation activation|nmod|overexpression overexpression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 5a-dihydrotestosterone|appos|start_entity that|nmod|5a-dihydrotestosterone have|nmod|that have|dobj|affinity affinity|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 detectable|nmod|start_entity detectable|nsubj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibit|dobj|start_entity inhibit|nsubj|acts acts|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 overload|compound|start_entity contribute|nsubj|overload contribute|dep|patients patients|nmod|mutations mutations|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 kinase|compound|start_entity kinase|nsubj|kit kit|appos|cd117 cd117|dep|end_entity 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 generation|nmod|start_entity end_entity|nsubj|generation 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 increased|nsubj|start_entity increased|dobj|expression expression|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentrations|nmod|start_entity activity|nmod|concentrations activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthesis|amod|start_entity stimulator|nmod|synthesis protein|acl:relcl|stimulator receptor|nmod|protein receptor|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 produced|ccomp|start_entity indicated|ccomp|produced indicated|nsubj|results results|nmod|experiments experiments|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 metabolism|amod|start_entity regulator|nmod|metabolism regulator|acl:relcl|inhibits inhibits|dobj|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 exacerbate|nsubj|start_entity exacerbate|dobj|actions actions|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 blocked|ccomp|start_entity blocked|nmod|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 2.000000 0 3.000000 0 0.000000 0 kinase|compound|start_entity acts|dobj|kinase acts|nsubj|pituitary_adenylate_cyclase-activating_protein pituitary_adenylate_cyclase-activating_protein|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effects|nmod|start_entity caused|nsubjpass|effects caused|nmod|inhibition inhibition|nmod|factors factors|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 tolerance|compound|start_entity variations|nmod|tolerance correlated|nsubjpass|variations correlated|nmod|sense sense|nmod|release release|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 total|dobj|start_entity plasma|dep|total using|nmod|plasma end_entity|xcomp|using 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 effect|nmod|start_entity reinforced|dobj|effect reinforced|nmod|hepatectomy hepatectomy|dep|mitigation mitigation|nmod|upregulation upregulation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptor|compound|start_entity form|nmod|receptor represent|dobj|form represent|nsubj|receptor receptor|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transporter-1|advmod|start_entity level|amod|transporter-1 level|compound|ceruloplasmin ceruloplasmin|amod|transporter-2 transporter-2|dep|eaat-2 eaat-2|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 concentration|compound|start_entity changes|nmod|concentration end_entity|nsubj|changes 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 properties|nmod|start_entity affected|nsubj|properties affected|advcl|present present|nmod|fact fact|dep|that that|dep|binding binding|nmod|results results|nmod|activation activation|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 control|compound|start_entity maintain|dobj|control maintain|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 ameliorate|nsubj|start_entity increases|ccomp|ameliorate increases|dobj|levels levels|nmod|apolipoprotein_e apolipoprotein_e|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 activity|nmod|start_entity neutralizes|dobj|activity antibody|acl:relcl|neutralizes performed|nmod|antibody technique|acl|performed purified|nmod|technique molecule|acl:relcl|purified interferon-gamma|dep|molecule interferon-gamma|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 defects|nmod|start_entity defects|dep|channels channels|acl|composed composed|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 transport|compound|start_entity inhibitor|nmod|transport nbti|dep|inhibitor thioinosine|appos|nbti thioinosine|dep|adenine adenine|appos|ehna ehna|dep|inhibitor inhibitor|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 transporter|amod|start_entity significance|nmod|transporter remains|nsubj|significance remains|advcl|demonstrated demonstrated|ccomp|associated associated|nsubjpass|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 enhanced|nmod|start_entity enhanced|nmod|presence presence|nmod|physostigmine physostigmine|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nsubj|a-syn a-syn|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 hs-crp|compound|start_entity hs-crp|dep|end_entity 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 29.000000 0 0.000000 0 3.000000 0 59.000000 0 0.000000 0 production|amod|start_entity correlated|nmod|production correlated|nsubj|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 combined|nmod|start_entity alpha-interferon|acl|combined alpha-interferon|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 adsorption|nummod|start_entity adsorption|acl:relcl|similar similar|nmod|those those|acl|observed observed|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 _|compound|start_entity inhibitor|appos|_ inhibitor|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|nmod|start_entity decrease|nmod|levels inhibition|nsubj|decrease inhibition|nmod|effect effect|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 tension|compound|start_entity expressed|nmod|tension expressed|nmod|conditions conditions|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 receptor|amod|start_entity channel|dep|receptor coupling|nmod|channel coupling|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 import|nmod|start_entity regulates|dobj|import regulates|advcl|regulates regulates|nsubj|form form|nmod|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 23.000000 0 2.000000 0 1.000000 0 metabolism|compound|start_entity correlated|nmod|metabolism correlated|nsubjpass|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|acl|generated generated|nmod|reaction reaction|nmod|no_synthase no_synthase|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 8.000000 0 ability|nmod|start_entity inhibit|dobj|ability determine|ccomp|inhibit incubated|advcl|determine incubated|nmod|camp camp|nmod|presence presence|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 >|acl|start_entity losartan|nsubj|> >|acl:relcl|losartan binding|dep|> binding|dep|candesartan candesartan|nmod|receptors receptors|compound|end_entity 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 repair|nmod|start_entity role|nmod|repair has|dobj|role has|nsubj|1 1|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 factor|compound|start_entity encodes|dobj|factor known|advcl|encodes known|nmod|function function|nmod|isoform isoform|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 concentration|compound|start_entity dosage|nmod|concentration dosage|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 ratios|nmod|start_entity alter|dobj|ratios increased|advcl|alter increased|dobj|activity activity|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 exposure|compound|start_entity increased|nsubj|exposure increased|nmod|field field|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transport|compound|start_entity regulating|dobj|transport decreasing|advcl|regulating plays|advcl|decreasing plays|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 challenge|compound|start_entity determined|nmod|challenge ratios|acl|determined ratios|compound|glucose glucose|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 start_entity|appos|progesterone progesterone|appos|end_entity 0.000000 0 0.000000 0 3.000000 0 1.000000 0 0.000000 0 11.000000 0 0.000000 0 1.000000 0 5.000000 0 1.000000 0 attenuate|compound|start_entity attenuate|acl|circulating circulating|nmod|patients patients|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|appos|inhibitor inhibitor|nmod|efficacy efficacy|amod|polymerase polymerase|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 clear|dobj|start_entity serves|xcomp|clear translocation|acl:relcl|serves translocation|nmod|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 17.000000 0 5.000000 0 0.000000 0 methods|dep|start_entity methods|appos|inhibitor inhibitor|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 provocation|nmod|start_entity responses|nmod|provocation responses|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 12.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 stress|amod|start_entity produces|dobj|stress enzyme|acl:relcl|produces end_entity|appos|enzyme 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 conversion|amod|start_entity conversion|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 effects|nmod|start_entity indicate|nsubj|effects indicate|ccomp|contribute contribute|nsubj|action action|nummod|end_entity 1.000000 0 2.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod:poss|start_entity mediate|dobj|effects mediate|nsubj|subunit subunit|compound|end_entity 2.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity selected|nsubj|treatment selected|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 2.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 fetmpyp|dep|start_entity fetmpyp|appos|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 dependency|compound|start_entity show|dobj|dependency show|advcl|suggesting suggesting|dobj|regulation regulation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 12-o-tetradecanoyl-phorbol-13-acetate|appos|start_entity induced|nmod|12-o-tetradecanoyl-phorbol-13-acetate effects|acl|induced effects|nmod|triptolide triptolide|nmod|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 residues|compound|start_entity participate|nsubj|residues indicating|ccomp|participate disassembly|xcomp|indicating disassembly|nmod|dephosphorylation dephosphorylation|nmod|end_entity 0.000000 0 0.000000 0 7.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 gamma|compound|start_entity gamma|amod|phosphatase phosphatase|dep|2 2|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 start_entity|nmod|markers markers|dep|glucocorticoid_receptor glucocorticoid_receptor|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 circulating|dobj|start_entity fluctuating|advcl|circulating diurnally|acl|fluctuating actions|nmod|diurnally antagonizing|dobj|actions regulates|advcl|antagonizing regulates|nmod|acetylation acetylation|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 functions|dep|start_entity functions|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 equivalent|compound|start_entity price|nmod|equivalent price|appos|e e|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 using|dobj|start_entity confirmed|xcomp|using confirmed|nsubjpass|end_entity 4.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pool|compound|start_entity degrade|dobj|pool degrade|nsubj|sequentially sequentially|amod|ectonucleotidases ectonucleotidases|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 capacity|nmod|start_entity capacity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 11.000000 0 16.000000 0 0.000000 0 4.000000 0 0.000000 0 grown|nmod|start_entity cells|acl|grown expressed|nmod|cells expressed|nsubjpass|proteins proteins|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 pathway|amod|start_entity important|nsubj|pathway important|nmod|resensitization resensitization|nmod|end_entity 0.000000 0 0.000000 0 10.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 3.000000 0 b-oxidation|nsubj|start_entity stimulate|xcomp|b-oxidation found|ccomp|stimulate found|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 resistant|nmod|start_entity lines|acl:relcl|resistant derivatives|nmod|lines using|dobj|derivatives test|xcomp|using vitro|xcomp|test interacting|advcl|vitro interacting|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 stimuli|appos|start_entity one|nmod|stimuli play|nsubj|one play|dobj|role role|nmod|activation activation|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 reductase|amod|start_entity subunit|nmod|reductase thymidine_kinase_1|appos|subunit expressions|nmod|thymidine_kinase_1 expressions|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 epitopes|compound|start_entity produced|iobj|epitopes produced|nsubj|cotransfection cotransfection|nmod|cdna cdna|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 administration|amod|start_entity days|nmod|administration decreased|nmod|days decreased|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 cause|nsubj|start_entity cause|dobj|increase increase|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity attenuates|dobj|effect niacin/laropiprant|ccomp|attenuates resistance|amod|niacin/laropiprant associated|nmod|resistance associated|nsubj|increase increase|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 reversed|nmod|start_entity effect|acl:relcl|reversed serum|appos|effect presence|nmod|serum delayed|nmod|presence delayed|nmod|agreement agreement|nmod|effect effect|nmod|inhibitors inhibitors|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 11.000000 0 0.000000 0 0.000000 0 0.000000 0 reduced|nmod|start_entity enhanced|parataxis|reduced enhanced|csubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 transport|compound|start_entity required|nmod|transport required|nmod|strains strains|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 uptake|compound|start_entity hamper|dobj|uptake proteins|acl:relcl|hamper signaling|dobj|proteins end_entity|acl|signaling 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 transporter|compound|start_entity transporter|dep|region region|nmod|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 23.000000 0 2.000000 0 1.000000 0 profiles|nmod|start_entity correlated|nsubjpass|profiles correlated|nmod|genotype genotype|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 3.000000 0 0.000000 0 generation|compound|start_entity generation|nmod|treatment treatment|dep|activity activity|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 9.000000 0 effects|nmod|start_entity increases|nmod|effects increases|nsubj|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 generation|amod|start_entity smc|nsubj|generation smc|parataxis|causes causes|dobj|relaxation relaxation|nmod|part part|nmod|activation activation|nmod|cyclase cyclase|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 antagonist|appos|start_entity abolished|nmod|antagonist induce|ccomp|abolished induce|nsubj|end_entity 0.000000 0 4.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 intake|compound|start_entity intake|nmod|gastric_cancer gastric_cancer|nmod|regard regard|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 deficits|compound|start_entity fell|nmod|deficits fell|nsubj|release release|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 stimulation|compound|start_entity using|dobj|stimulation evaluated|advcl|using evaluated|nsubjpass|secretion secretion|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 start_entity|ccomp|demonstrated demonstrated|ccomp|coupled coupled|nmod|receptors receptors|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 had|nsubj|start_entity had|advcl|indicating indicating|advcl|deficient deficient|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 ruled|nmod|start_entity _|ccomp|ruled _|nsubj|_ _|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 balance|compound|start_entity role|nmod|balance plays|dobj|role plays|nsubj|repulsive_guidance_molecule_c repulsive_guidance_molecule_c|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 administration|nmod|start_entity effects|nmod|administration compared|nsubjpass|effects compared|nmod|that that|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 addition|nmod|start_entity blocked|nsubj|addition blocked|dobj|activation activation|nmod|kinases kinases|appos|end_entity 0.000000 0 2.000000 0 0.000000 0 1.000000 0 2.000000 0 2.000000 0 13.000000 0 0.000000 0 1.000000 0 0.000000 0 recruitment|compound|start_entity recruitment|nmod|end_entity 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 examine|nmod|start_entity examine|parataxis|labeled labeled|nsubjpass|cholesterol_acyltransferase cholesterol_acyltransferase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity rats|nmod|treatment modulation|nmod|rats modulation|nmod|neurotrophins neurotrophins|nmod|family family|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 utilization|compound|start_entity utilization|nmod|vivo vivo|nmod|activation activation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 incubated|nmod|start_entity incubated|nmod|wells wells|nmod|atmosphere atmosphere|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 donor|compound|start_entity donor|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 4.000000 0 4.000000 0 0.000000 0 measurement|nmod|start_entity using|nmod|measurement evaluated|advcl|using evaluated|nsubjpass|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 prevents|nmod|start_entity prevents|dobj|increase increase|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 channels|compound|start_entity effects|nmod|channels compared|nsubjpass|effects compared|nmod|cells cells|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 homeostasis|compound|start_entity regulator|nmod|homeostasis acts|nmod|regulator peptide|acl:relcl|acts peptide|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 11.000000 0 0.000000 0 4.000000 0 12.000000 0 1.000000 0 pd123319|compound|start_entity pd123319|dep|angiotensin_ii angiotensin_ii|appos|losartan losartan|appos|pd123319 pd123319|compound|end_entity 0.000000 0 4.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|appos|molecule molecule|acl|generated generated|nmod|ho-1 ho-1|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 trafficking|compound|start_entity reduce|dobj|trafficking reduce|nsubj|mutations mutations|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 treatment|amod|start_entity affected|nmod|treatment affected|nsubjpass|expression expression|amod|end_entity 0.000000 0 2.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 showed|nmod|start_entity showed|nsubj|women women|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 dismutase|amod|start_entity albumin|dep|dismutase albumin|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 accumulation|compound|start_entity due|nsubj|accumulation due|nmod|inhibition inhibition|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 circulating|dobj|start_entity effects|acl|circulating mediated|nsubjpass|effects mediated|nmod|system system|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 mixed|nsubjpass|start_entity mixed|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 kinase|amod|start_entity sensitivity|nmod|kinase inhibitors|amod|sensitivity predict|dobj|inhibitors predict|nsubj|mutations mutations|nmod|domain domain|amod|end_entity 0.000000 0 0.000000 0 14.000000 0 2.000000 0 0.000000 0 10.000000 0 0.000000 0 4.000000 0 2.000000 0 2.000000 0 breakdown|compound|start_entity responsible|nmod|breakdown enzyme|amod|responsible polymorphisms|appos|enzyme polymorphisms|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 3.000000 0 0.000000 0 2.000000 0 3.000000 0 1.000000 0 sparing|nmod|start_entity depend|nmod|sparing depend|nsubj|actions actions|nmod|inhibitors inhibitors|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 requirement|compound|start_entity correspond|nsubj|requirement correspond|nmod|those those|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|compound|start_entity measurement|nmod|uptake examined|nmod|measurement examined|nsubjpass|levels levels|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 derivatives|amod|start_entity activity|nmod|derivatives effect|nmod|activity had|dobj|effect had|nsubj|alpha-difluoromethylornithine alpha-difluoromethylornithine|appos|inhibitor inhibitor|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 domain|compound|start_entity placed|nsubjpass|domain placed|nmod|context context|acl:relcl|allows allows|advcl|vary vary|advcl|neutralized neutralized|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 min|nmod|start_entity decreased|nsubj|min decreased|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 cotransporter|amod|start_entity clone|nmod|cotransporter using|dobj|clone obtained|xcomp|using obtained|nsubjpass|clones clones|nmod|carrier carrier|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 waves|compound|start_entity production|nmod|waves explain|nmod|production explain|nmod|conditions conditions|acl:relcl|altered altered|nsubjpass|gating gating|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 activity|compound|start_entity present|nsubj|activity +|dep|present end_entity|nsubj|+ 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 incorporation|nmod|start_entity step|appos|incorporation catalyzed|nsubjpass|step catalyzed|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 users|compound|start_entity %|nmod|users switched|nsubjpass|% switched|nmod|use use|nmod|statin statin|acl|achieve achieve|dobj|goal goal|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 sensitivity|compound|start_entity associated|nmod|sensitivity associated|nsubj|haplotype haplotype|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 gradients|amod|start_entity subjected|nmod|gradients showed|advcl|subjected showed|nsubj|receptors receptors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 administration|nmod|start_entity evidence|nmod|administration excluded|nmod|evidence excluded|nmod|inhibition inhibition|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 penetration|nsubj|start_entity penetration|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 expressed|advcl|start_entity expressed|dobj|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 uptake|nmod|start_entity inhibits|dobj|uptake inhibits|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 secretion|amod|start_entity peptide|nmod|secretion peptide|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 stimulation|compound|start_entity produces|nsubj|stimulation produces|dobj|transcripts transcripts|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 injection|compound|start_entity found|nmod|injection found|nmod|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 synthesis|compound|start_entity rhythm|nmod|synthesis drives|dobj|rhythm enzyme|acl:relcl|drives arylalkylamine_n-acetyltransferase|appos|enzyme encodes|dobj|arylalkylamine_n-acetyltransferase aanat|acl:relcl|encodes contains|nsubj|aanat contains|dobj|element element|nmod|promoter promoter|acl:relcl|heterodimers heterodimers|amod|capable capable|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 infusion|nmod|start_entity showed|nsubj|infusion showed|ccomp|responsible responsible|advmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 htra2|amod|start_entity role|nmod|htra2 identified|nsubjpass|role identified|nmod|mice mice|acl|lacking lacking|dobj|expression expression|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 acini|amod|start_entity labeling|nmod|acini reduce|dep|labeling reduce|nsubj|octapeptide octapeptide|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|nsubj|gsk-3b gsk-3b|amod|similarly similarly|nmod|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 0.000000 0 decarboxylase|amod|start_entity encoding|dobj|decarboxylase observed|parataxis|encoding observed|nsubjpass|induction induction|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 type|compound|start_entity ii|dep|type sub-grouped|dep|ii sub-grouped|nmod|angiotensin-converting_enzyme angiotensin-converting_enzyme|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 transporters|compound|start_entity expression|nmod|transporters expression|dep|evidence evidence|nmod|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 13.000000 0 0.000000 0 0.000000 0 reversed|nmod|start_entity reversed|nsubj|effect effect|nmod|forskolin forskolin|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4|amod|start_entity hydroxylation|nmod:poss|4 showed|nmod|hydroxylation showed|nmod|preference preference|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 effects|nmod:poss|start_entity gene-methylation|nmod|effects gene-methylation|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 test|compound|start_entity model|nmod|test measured|nmod|model quartiles|dep|measured separating|nmod|quartiles defining|advcl|separating defining|dobj|profile profile|nmod|resistance resistance|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 presence|nmod|start_entity peptide|nmod|presence allows|nmod|peptide allows|dobj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 employed|xcomp|start_entity employed|nmod|advent advent|nmod|inhibitor inhibitor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 4.000000 0 15.000000 0 0.000000 0 2.000000 0 1.000000 0 zap-70|compound|start_entity recruited|nsubjpass|zap-70 recruited|nmod|stimulation stimulation|nmod|kinetics kinetics|amod|similar similar|nmod|that that|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 inhibitors|dep|start_entity prevented|nsubj|inhibitors demonstrate|ccomp|prevented demonstrate|parataxis|activation activation|nmod|end_entity 0.000000 0 2.000000 0 0.000000 0 1.000000 0 4.000000 0 4.000000 0 10.000000 0 0.000000 0 0.000000 0 0.000000 0 ratio|compound|start_entity detectable|nsubj|ratio meant|parataxis|detectable meant|ccomp|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|acl|synergized synergized|nmod|induction induction|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity investigated|dobj|effects investigated|nmod|intake intake|acl|induced induced|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 converts|xcomp|start_entity stimulation|acl:relcl|converts stimulation|nsubj|mechanism mechanism|acl:relcl|inhibits inhibits|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 treatment|nmod|start_entity produced|nmod|treatment levels|acl|produced relate|nmod|levels relate|nsubj|potencies potencies|nmod|variants variants|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 phosphorylation|amod|start_entity levels|nmod|phosphorylation examining|dobj|levels compared|advcl|examining compared|nsubjpass|activities activities|nmod|variants variants|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 using|dobj|start_entity have|xcomp|using have|nsubj|addition addition|nmod|inhibition inhibition|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 3.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|nmod|start_entity sensitive|nmod|treatment sensitive|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 kinases|compound|start_entity association|nmod|kinases activity|nmod|association has|dobj|activity has|nsubj|antigen antigen|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 enhancement|amod|start_entity enhancement|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 etoposide|appos|start_entity etoposide|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 decreased|dobj|start_entity decreased|advcl|increased increased|dobj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 reabsorption|amod|start_entity mechanism|nmod|reabsorption mechanism|nsubj|apical_sodium-dependent_bile_acid_transporter apical_sodium-dependent_bile_acid_transporter|appos|asbt asbt|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 factor|dep|start_entity factor|acl:relcl|mediates mediates|nsubj|receptor receptor|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 goals|compound|start_entity goals|nmod|tc tc|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 effector|nmod|start_entity end_entity|appos|effector 6.000000 0 0.000000 0 2.000000 0 6.000000 0 0.000000 0 14.000000 0 0.000000 0 3.000000 0 2.000000 0 2.000000 0 production|nmod|start_entity presence|nmod|production incubated|nmod|presence derived|advcl|incubated cell|acl|derived observed|nsubj|cell treg|ccomp|observed evident|advcl|treg evident|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|dep|concentration concentration|dep|considering considering|dobj|genotype genotype|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 essential|nsubj|start_entity essential|nmod|glycosylation glycosylation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 element|nsubj|start_entity element|nmod|loop loop|nmod|receptor receptor|amod|end_entity 0.000000 0 0.000000 0 18.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 pretreated|nmod|start_entity suppressed|advcl|pretreated suppressed|nsubjpass|upregulation upregulation|nmod|protein protein|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity elevation|nmod|levels explained|nsubjpass|elevation explained|nmod|inhibition inhibition|nmod|catabolism catabolism|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 treatment|compound|start_entity stability|nmod|treatment explain|nsubj|stability explain|dobj|decrease decrease|nmod|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 transport|compound|start_entity stimulate|dobj|transport stimulate|nsubj|elevation elevation|nmod|concentration concentration|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 produce|nsubj|start_entity produce|ccomp|unable unable|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity levels|acl|intensified intensified|dobj|activity activity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 relaxation|nmod|start_entity investigated|nsubjpass|relaxation investigated|nmod|devices devices|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 kinase|amod|start_entity inhibitor|amod|kinase proliferation|nsubj|inhibitor had|advcl|proliferation had|dobj|effect effect|nmod|mmp-9 mmp-9|acl|induced induced|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pretreatment|nmod|start_entity important|nmod|pretreatment important|nsubj|effect effect|nmod|dose dose|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 sequences|amod|start_entity suggests|nmod|sequences suggests|ccomp|encode encode|dobj|form form|amod|functional functional|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 influenced|nsubjpass|start_entity influenced|parataxis|loaded loaded|nmod|substrate substrate|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|acl|caused caused|nmod|decrease decrease|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 genes|amod|start_entity genes|dep|tyms tyms|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 4.000000 0 -lsb-|nummod|start_entity 8-hydroxy-2|nmod:npmod|-lsb- concentration-dependently|amod|8-hydroxy-2 concentration-dependently|amod|end_entity 2.000000 0 1.000000 0 1.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptor|appos|start_entity focused|nmod|receptor focused|advcl|causing causing|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 that|nmod|start_entity slower|nmod|that slower|nsubj|recovery recovery|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 transferrin_receptor|dep|start_entity transferrin_receptor|dep|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 7.000000 0 12.000000 0 0.000000 0 study|nmod|start_entity study|nmod|epidermal_growth_factor_receptor epidermal_growth_factor_receptor|appos|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 control|compound|start_entity compare|dobj|control compare|nmod|administration administration|nmod|aspart aspart|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 action|amod|start_entity end_entity|dep|action 1.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transporters|compound|start_entity caused|nmod|transporters caused|nsubj|oocytes oocytes|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 anaemia|compound|start_entity corrects|dobj|anaemia corrects|nsubj|reduction reduction|nmod|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 levels|nmod|start_entity levels|acl|implicated implicated|nmod|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 phosphorylation|amod|start_entity undergo|dobj|phosphorylation achieved|advcl|undergo achieved|nmod|time time|appos|identification identification|nmod|sites sites|nmod|protein protein|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 signal|amod|start_entity mediator|nmod|signal provide|nmod|mediator provide|dobj|support support|nmod|receptor_activator_of_nf-kb_ligand receptor_activator_of_nf-kb_ligand|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 accumulation|compound|start_entity decrease|dobj|accumulation decrease|advcl|downregulating downregulating|dobj|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 synthesis|appos|start_entity synthesis|acl|induced induced|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 homeostasis|compound|start_entity homeostasis|appos|24dhcr 24dhcr|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 levels|nmod|start_entity face|nmod|levels vital|nmod|face vital|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 treated|nmod|start_entity mice|acl|treated decreased|nmod|mice decreased|nsubjpass|levels levels|nmod|receptors receptors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 hydroylase|amod|start_entity hydroylase|appos|h h|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 family|amod|start_entity member|nmod|family member|appos|retinoid_x_receptor_alpha retinoid_x_receptor_alpha|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranoside|appos|start_entity ampk|nmod|5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranoside stimulation|nmod|ampk induced|nsubj|stimulation restored|advcl|induced restored|nsubj|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 waves|compound|start_entity evoked|nsubj|waves evoked|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 response|compound|start_entity increased|dobj|response increased|advcl|indicating indicating|xcomp|distinct distinct|nmod|modulator modulator|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 structure|nmod|start_entity using|dobj|structure replacement|acl|using determined|nmod|replacement determined|nsubjpass|structure structure|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 excursions|compound|start_entity lower|nsubj|excursions lower|nmod|lispro lispro|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 channels|compound|start_entity channels|amod|alpha-subunit alpha-subunit|nmod|heart heart|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 pretreatment|compound|start_entity associated|nsubjpass|pretreatment associated|nmod|frequency frequency|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity moderated|nsubjpass|effects moderated|nmod|polymorphisms polymorphisms|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 levels|acl|start_entity levels|appos|products products|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 pyrophosphatase|amod|start_entity end_entity|appos|pyrophosphatase 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 oxidation|amod|start_entity enhances|dobj|oxidation enhances|advcl|essential essential|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 interact|nsubj|start_entity interact|nmod|subtypes subtypes|appos|end_entity 1.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 lead|nmod|start_entity lead|nsubj|mutations mutations|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 2.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 disposal|compound|start_entity decrease|dobj|disposal decrease|nsubj|concentrations concentrations|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 17.000000 0 0.000000 0 involved|nmod|start_entity involved|nsubjpass|er-alpha36 er-alpha36|amod|end_entity 2.000000 0 0.000000 0 13.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 metalloprotease|compound|start_entity metalloprotease|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 serotonin|appos|start_entity taking|dobj|serotonin function|acl|taking serves|dobj|function serves|nsubj|serotonin_transporter serotonin_transporter|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 diet|compound|start_entity change|nsubj|diet change|dobj|levels levels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 produced|nmod|start_entity inhibited|ccomp|produced inhibited|dobj|induction induction|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 intolerance|compound|start_entity contraindications|nmod|intolerance administered|nmod|contraindications agents|acl:relcl|administered agents|nsubj|inhibitors inhibitors|appos|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|dobj|associates associates|amod|insulin_receptor_substrate_1 insulin_receptor_substrate_1|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 19-9|amod|start_entity expression|nmod|19-9 end_entity|appos|expression 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 phosphorylation|amod|start_entity phosphorylation|nmod|hgf_receptor hgf_receptor|appos|end_entity 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 doses|nmod|start_entity caused|nsubj|doses caused|dobj|elevations elevations|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 stimulation|amod|start_entity due|nmod|stimulation increases|advcl|due determined|advcl|increases determined|ccomp|accompanied accompanied|nmod|expression expression|nmod|genes genes|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 phosphorylation|amod|start_entity induced|nsubj|phosphorylation induced|advcl|pretreated pretreated|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 activities|amod|start_entity reduced|nsubjpass|activities reduced|nmod|/ /|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 stress|amod|start_entity induction|nmod|stress end_entity|acl|induction 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 uptake|nmod|start_entity chlorate-resistant|nmod|uptake chlorate-resistant|nsubj|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 trp_ankyrin_1|appos|start_entity trp_ankyrin_1|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 signals|amod|start_entity intracellular|dobj|signals intracellular|nsubj|transduces transduces|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 displaced|nmod|start_entity sites|acl|displaced localized|nsubj|sites localized|xcomp|supporting supporting|ccomp|exist exist|nsubj|receptors receptors|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 lead|xcomp|start_entity plays|advcl|lead plays|nsubj|gene gene|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 enantiomer|amod|start_entity enantiomer|nmod|groups groups|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 3.000000 0 0.000000 0 start_entity|dep|cbd cbd|dep|antagonist antagonist|nummod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity evaluated|nsubjpass|effect evaluated|nmod|receptor-negative receptor-negative|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 reduce|dobj|start_entity directed|dep|reduce directed|nsubj|probes probes|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 sites|compound|start_entity depletion|nmod|sites associated|nsubj|depletion associated|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 increment|nmod|start_entity induced|dobj|increment end_entity|acl|induced 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 suppressed|nmod|start_entity suppressed|nmod|antagonism antagonism|nmod|end_entity 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentration|amod|start_entity reduces|dobj|concentration +|advcl|reduces modulates|dep|+ modulates|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 blocked|nmod|start_entity blocked|xcomp|suggesting suggesting|ccomp|involved involved|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 5.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 wasting|compound|start_entity associated|nmod|wasting associated|nsubjpass|states states|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 pvi|nmod|start_entity day|nmod|pvi fbal|nmod|day auc0-10h|nmod|fbal /|nsubj|auc0-10h /|advcl|hr/ml hr/ml|nmod|day day|nmod|treatment treatment|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 lipidate|nmod|start_entity lipidate|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 2.000000 0 0.000000 0 use|dobj|start_entity ability|acl|use requires|nsubj|ability requires|dobj|regulator regulator|acl:relcl|turns turns|nmod|expression expression|nmod|genes genes|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 salts|compound|start_entity improved|advcl|salts improved|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 start_entity|nmod|cytotoxicity cytotoxicity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 signaling|compound|start_entity stimulated|nmod|signaling genes|acl:relcl|stimulated persists|nmod|genes persists|nsubj|activity activity|compound|end_entity 1.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 effects|nmod|start_entity counteract|dobj|effects counteract|nsubj|inhibitors inhibitors|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 preference|nmod|start_entity irrespective|nmod|preference suppressed|advmod|irrespective suppressed|dobj|production production|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 induction|compound|start_entity associated|nsubjpass|induction associated|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 biosynthesis|amod|start_entity step|nmod|biosynthesis limiting|dobj|step rate|acl|limiting catalyzes|dobj|rate monoxygenase|acl:relcl|catalyzes encodes|dobj|monoxygenase encodes|nsubj|gene gene|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 inhibitors|appos|start_entity rings|nmod|inhibitors denuded|dobj|rings endothelium|acl|denuded present|nmod|endothelium seems|advcl|present seems|xcomp|associated associated|nmod|receptors receptors|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|acl|triggering triggering|dobj|enhancement enhancement|nmod|nanoclusters nanoclusters|nmod|assays assays|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 depletion|compound|start_entity increases|nmod|depletion increases|parataxis|related related|nsubjpass|number number|nmod|receptors receptors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 target|nmod|start_entity target|nsubj|motif motif|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 implicated|nmod|start_entity implicated|nmod|destabilization destabilization|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 start_entity|nmod|day day|acl|followed followed|nmod|vaccinations vaccinations|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 production|amod|start_entity accompanied|nsubjpass|production accompanied|nmod|mrna mrna|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 6.000000 0 3.000000 0 family|amod|start_entity members|nmod|family members|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 modulation|nmod|start_entity homeostasis|nsubj|modulation homeostasis|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 reduced|nmod|start_entity lps|acl:relcl|reduced obtained|nmod|lps lungs|acl|obtained caused|nmod|lungs caused|nmod|expression expression|nmod|protein protein|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 activity|compound|start_entity upregulates|dobj|activity upregulates|nmod|increase increase|nmod|expression expression|nummod|end_entity 0.000000 0 0.000000 0 10.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 46.000000 0 4.000000 0 2.000000 0 usage|compound|start_entity effects|nmod|usage had|dobj|effects had|nsubj|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 15.000000 0 0.000000 0 1.000000 0 levels|compound|start_entity elevated|nsubj|levels increased|dep|elevated increased|nmod|hearts hearts|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 channel|compound|start_entity acts|nmod|channel acts|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 21.000000 0 3.000000 0 1.000000 0 play|nmod|start_entity play|dobj|role role|nmod|regulation regulation|nmod|induction induction|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 challenge|compound|start_entity resulted|nsubj|challenge resulted|nmod|development development|acl|multidrug multidrug|nmod|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 2.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 displaced|nmod|start_entity sr141716a|acl:relcl|displaced sites|nmod|sr141716a transcripts|appos|sites transcripts|nmod|end_entity 1.000000 0 0.000000 0 4.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 binding|compound|start_entity reduced|nsubjpass|binding reduced|nmod|edta edta|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 19-9|amod|start_entity using|dobj|19-9 advantage|acl|using advantage|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 lectin|dep|start_entity end_entity|appos|lectin 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 increased|dobj|start_entity increased|advcl|inducing inducing|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 saturation|compound|start_entity binding|nsubj|saturation increasing|xcomp|binding effect|acl|increasing chromatography|dep|effect chromatography|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 kinases|amod|start_entity kinases|dep|sorafenib sorafenib|dep|targets targets|dobj|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 start_entity|nmod|responses responses|nmod|challenge challenge|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 homeostasis|compound|start_entity regulated|nsubjpass|homeostasis regulated|nmod|stabilization stabilization|nmod|mrna mrna|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effective|nsubj|start_entity effective|advcl|blocking blocking|nmod|range range|nmod|rates rates|compound|end_entity 0.000000 0 4.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 presence|nmod|start_entity detected|nmod|presence correlated|advcl|detected correlated|nmod|activation activation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|appos|glucose glucose|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 11.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 hormones|amod|start_entity circulate|nsubj|hormones circulate|nmod|blood blood|acl|bound bound|nmod|proteins proteins|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 activity|amod|start_entity inhibition|nmod|activity showed|dobj|inhibition showed|nmod|levels levels|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 derivatives|amod|start_entity bind|nsubj|derivatives bind|nmod|ligands ligands|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 accumulation|compound|start_entity inhibition|nmod|accumulation explained|nsubjpass|inhibition explained|nmod|reduction reduction|nmod|binding binding|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 2|appos|start_entity 2|dep|not not|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 signalling|amod|start_entity signalling|nmod|activation activation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 transport|compound|start_entity effects|nmod|transport unknown|nsubj|effects used|parataxis|unknown used|xcomp|study study|dobj|role role|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 4.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 presence|nmod|start_entity h|nmod|presence preincubated|nmod|h bodies|acl:relcl|preincubated incubations|nmod|bodies measured|nmod|incubations measured|nsubjpass|incorporation incorporation|nmod|-rsb- -rsb-|amod|leucine leucine|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 encephalitis|compound|start_entity associated|nmod|encephalitis associated|nsubjpass|polymorphisms polymorphisms|nmod|gene gene|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 transport|compound|start_entity mediated|nsubjpass|transport mediated|nmod|uniporter uniporter|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 synthesis|amod|start_entity escape|nsubj|synthesis termed|ccomp|escape control|parataxis|termed control|advcl|inhibitors inhibitors|nsubj|angiotensin-converting_enzyme angiotensin-converting_enzyme|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 levels|amod|start_entity decrease|nmod|levels evidenced|nmod|decrease evidenced|nmod|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 entry|nmod|start_entity enhance|dobj|entry enhance|nsubj|sr sr|dep|associates associates|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 inhibited|dobj|start_entity inhibited|advcl|reduced reduced|dobj|uptake uptake|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 interaction|nmod|start_entity formed|nmod|interaction radical|dep|formed species|nsubj|radical indicates|ccomp|species indicates|nsubj|breakage breakage|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 reduced|nsubj|start_entity reduced|nmod|absence absence|nmod|end_entity 3.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 5.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|amod|binding binding|nmod|sex_hormone-binding_globulin sex_hormone-binding_globulin|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 had|nsubj|start_entity had|nmod|increases increases|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 sensitivity|amod|start_entity predict|dobj|sensitivity end_entity|acl:relcl|predict 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 4.000000 0 22.000000 0 0.000000 0 2.000000 0 0.000000 0 start_entity|nsubj|infusions infusions|nmod|inhibitor inhibitor|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity observed|nmod|treatment observed|nmod|tumors tumors|nmod|protein protein|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 efflux|compound|start_entity unaffected|nsubj|efflux unaffected|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 1.000000 0 0.000000 0 secretion|amod|start_entity end_entity|nsubj|secretion 0.000000 0 0.000000 0 0.000000 0 3.000000 0 2.000000 0 19.000000 0 0.000000 0 0.000000 0 20.000000 0 1.000000 0 abrogated|nmod|start_entity abrogated|nsubj|silencing silencing|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 reversed|nmod|start_entity rats|acl:relcl|reversed enhanced|nmod|rats enhanced|nmod|parallel parallel|nmod|increases increases|nmod|phosphorylation phosphorylation|nmod|end_entity 0.000000 0 2.000000 0 0.000000 0 1.000000 0 2.000000 0 2.000000 0 13.000000 0 0.000000 0 1.000000 0 0.000000 0 vanilloid|xcomp|start_entity vanilloid|nsubj|properties properties|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 application|compound|start_entity modifies|nmod|application modifies|nsubj|inhibition inhibition|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pretreatment|nmod|start_entity attenuates|nsubj|pretreatment attenuates|advcl|circulating circulating|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 f18|nummod|start_entity tomography|nmod|f18 background|dep|tomography has|nsubj|background has|dobj|imaging imaging|nmod|assessment assessment|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptors|amod|start_entity family|nmod|receptors signal|nmod|family signal|parataxis|represents represents|nsubj|inhibition inhibition|compound|end_entity 0.000000 0 0.000000 0 11.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 component|compound|start_entity component|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 p72|amod|start_entity p72|appos|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 kinases|compound|start_entity regulation|nmod|kinases analyse|dobj|regulation purified|advcl|analyse purified|dobj|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 homeostasis|compound|start_entity involved|nmod|homeostasis tissues|acl|involved found|nmod|tissues found|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transport|compound|start_entity involved|nmod|transport protein|acl|involved immunoreactivity|appos|protein immunoreactivity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 tested|advmod|start_entity tested|nsubjpass|antagonist antagonist|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 administration|acl|start_entity supported|nmod|administration treatment|acl|supported advancement|nmod|treatment represents|dobj|advancement represents|nsubj|inhibition inhibition|nmod|epidermal_growth_factor_receptor epidermal_growth_factor_receptor|appos|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 5.000000 0 12.000000 0 1.000000 0 0.000000 0 0.000000 0 increase|nsubj|start_entity increase|advcl|decrease decrease|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 reach|nsubj|start_entity reach|dobj|centers centers|nmod:poss|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 oxidase|amod|start_entity activity|amod|oxidase activity|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 isoform|compound|start_entity facilitative|dobj|isoform facilitative|nsubj|sequence sequence|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 13.000000 0 0.000000 0 0.000000 0 treatment|nmod|start_entity treatment|appos|analog analog|acl:relcl|hinders hinders|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 synthase|amod|start_entity isoform|nsubj|synthase used|advcl|isoform used|nsubjpass|mice mice|nmod|disruption disruption|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 lysophosphatidic_acid|appos|start_entity level|nmod|lysophosphatidic_acid controls|dobj|level controls|nmod|activity activity|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.0|nmod|start_entity -4.5|nmod|2.0 potential|dep|-4.5 potential|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 cells|amod|start_entity contributes|nmod|cells suggest|ccomp|contributes suggest|advcl|observations observations|dep|promotes promotes|dobj|degradation degradation|compound|end_entity 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 role|appos|start_entity role|dep|channels channels|nmod|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 had|nsubj|start_entity revert|advcl|had revert|dobj|decrease decrease|nmod|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 kinase|nsubj|start_entity clear|advcl|kinase clear|ccomp|regulates regulates|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 treatment|nmod|start_entity weeks|nmod|treatment unchanged|nmod|weeks unchanged|nsubj|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 9.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nmod|concentration concentration|appos|i i|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 treatment|amod|start_entity caused|nsubj|treatment caused|advcl|six-fold six-fold|advcl|increase increase|dep|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 affects|nsubj|start_entity affects|dobj|expression expression|compound|end_entity 8.000000 0 1.000000 0 3.000000 0 5.000000 0 6.000000 0 107.000000 1 18.000000 0 9.000000 0 22.000000 0 2.000000 0 screen|compound|start_entity using|dobj|screen using|nmod|receptors receptors|dep|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treated|nmod|start_entity rats|acl|treated consisted|nmod|rats group|acl|consisted group|acl:relcl|antagonist antagonist|amod|end_entity 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 effect|nmod|start_entity measure|dobj|effect measure|nsubj|antibodies antibodies|acl|recognizing recognizing|dobj|regions regions|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 intake|compound|start_entity produce|dobj|intake deprived|advcl|produce water|acl|deprived brain|nmod|water sensitizes|dobj|brain sensitizes|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 cni|dep|start_entity cni|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibited|nsubj|start_entity inhibited|iobj|mtor mtor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 2.000000 0 7.000000 0 1.000000 0 1.000000 0 1.000000 0 receptor|amod|start_entity cdnas|nmod|receptor cotransfected|nmod|cdnas cells|acl:relcl|cotransfected cells|amod|end_entity 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 endocytosis|nmod|start_entity stimulation|nmod|endocytosis reduced|nsubj|stimulation reduced|dobj|amount amount|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 labeling|nmod|start_entity labeling|appos|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 0.000000 0 antagonist|compound|start_entity elevated|nmod|antagonist pancreas|acl:relcl|elevated stimulated|nmod|pancreas stimulated|nsubj|results results|dep|glucose glucose|acl|enhanced enhanced|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treated|nmod|start_entity treated|nsubjpass|deficiency deficiency|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity induces|nsubj|treatment induces|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 kinase|compound|start_entity related|nsubjpass|kinase related|nmod|receptors receptors|amod|end_entity 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 induced|nsubj|start_entity induced|dobj|a a|dep|activation activation|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 14.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 formation|amod|start_entity days|nmod|formation m20|nmod|days gene|nmod|m20 gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 stimulated|nmod|start_entity populations|acl|stimulated inhibited|nmod|populations inhibited|nsubj|production production|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 activities|amod|start_entity harboring|dobj|activities protein|acl|harboring coding|nmod|protein gene|acl|coding gene|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 levels|nmod|start_entity buildup|nmod|levels allow|dobj|buildup allow|nsubj|inhibitors inhibitors|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthesis|appos|start_entity result|nsubj|synthesis result|nmod|action action|nmod|isoforms isoforms|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 apoptosis|nmod|start_entity delay|nmod|apoptosis profound|nsubj|delay profound|ccomp|produced produced|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|amod|start_entity involved|nmod|metabolism involved|nsubj|reductase reductase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 4.000000 0 retention|nmod|start_entity retention|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 1.000000 0 0.000000 0 concentration|compound|start_entity increased|dobj|concentration increased|nsubj|treatment treatment|nmod|cells cells|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 p|nsubj|start_entity showed|parataxis|p showed|nmod|levels levels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 biosynthesis|compound|start_entity biosynthesis|nummod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 sensitivity|compound|start_entity enhanced|dobj|sensitivity enhanced|nmod|lines lines|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptors|appos|start_entity containing|dobj|receptors subunit|acl|containing subunit|appos|end_entity 0.000000 0 0.000000 0 19.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 maintenance|amod|start_entity determinant|nmod|maintenance implicated|nmod|determinant implicated|nsubjpass|enzyme enzyme|appos|n1-acetyltransferase n1-acetyltransferase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 presence|nmod|start_entity elicited|nmod|presence elicited|nmod|effect effect|acl|obtained obtained|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 -lsb-|amod|start_entity activators|appos|-lsb- pretreated|nmod|activators pretreated|advcl|test test|ccomp|represents represents|nsubj|up-regulation up-regulation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 replacement|amod|start_entity results|nmod|replacement substitution|acl:relcl|results substitution|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 accelerated|nmod|start_entity hnf-4a|acl:relcl|accelerated hnf-4a|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitors|nmod|start_entity block|nsubj|inhibitors block|dobj|readouts readouts|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity followed|nmod|treatment cells|acl|followed sequence|nmod|cells containing|dobj|sequence increased|xcomp|containing increased|nsubjpass|activity activity|nmod|constructs constructs|acl|containing containing|dobj|promoter promoter|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 exposed|nmod|start_entity lines|acl|exposed expression|nmod|lines analysis|nmod|expression showed|nsubj|analysis showed|nmod|mrna mrna|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 1.000000 0 7.000000 0 3.000000 0 13.000000 0 0.000000 0 1.000000 0 0.000000 0 cells|appos|start_entity cells|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 14.000000 0 0.000000 0 1.000000 0 0.000000 0 sequence|amod|start_entity similar|nsubj|sequence similar|nmod|ucps ucps|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 regimens|compound|start_entity efficacy|nmod|regimens similar|nsubj|efficacy similar|nmod|patients patients|nmod|nsclc nsclc|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|compound|start_entity uptake|nmod|translocation translocation|nmod|membrane membrane|nmod|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 23.000000 0 2.000000 0 1.000000 0 start_entity|appos|isoform isoform|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|amod|start_entity enzymes|nmod|metabolism relevant|nsubj|enzymes relevant|nmod|therapy therapy|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 signaling|compound|start_entity plays|nsubj|signaling plays|nmod|actions actions|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 responses|amod|start_entity modulates|dobj|responses modulates|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 levels|compound|start_entity related|nmod|levels appear|advcl|related appear|nsubj|effect effect|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 dose|nmod|start_entity obtained|nmod|dose that|acl|obtained led|nmod|that led|xcomp|suggesting suggesting|dobj|role role|nmod|induction induction|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 generation|nmod|start_entity catalyzes|dobj|generation enzyme|acl:relcl|catalyzes enzyme|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 feeding|compound|start_entity altered|nmod|feeding altered|nsubjpass|content content|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 prostaglandin_e2|appos|start_entity regulate|nsubj|prostaglandin_e2 regulate|dobj|production production|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 2.000000 0 1.000000 0 5.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|dobj|phosphatase phosphatase|appos|mu mu|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 caspases|nmod|start_entity inhibitors|nmod|caspases inhibited|nsubj|inhibitors inhibited|dobj|processing processing|nmod|p32 p32|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|compound|start_entity regulation|nmod|metabolism regulation|dep|effects effects|nmod|apoproteins apoproteins|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 levels|compound|start_entity circulating|dobj|levels help|advcl|circulating help|nsubj|actions actions|nmod|conjunction conjunction|nmod|function function|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 consumption|nmod|start_entity assessed|nmod|consumption end_entity|ccomp|assessed 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 erk_1|appos|start_entity treatment|nmod|erk_1 abolished|nsubj|treatment abolished|dobj|phosphorylation phosphorylation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 2.000000 0 10.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity correlated|nmod|levels correlated|nsubjpass|locus locus|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 exposure|amod|start_entity due|nmod|exposure due|nmod|downregulation downregulation|nmod|sites sites|nummod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 accumulation|nmod|start_entity stimulated|dobj|accumulation stimulated|nsubj|gonadotropin-releasing_hormone gonadotropin-releasing_hormone|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 regulation|compound|start_entity study|dep|regulation resistance|dep|study resistance|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 investigated|nmod|start_entity investigated|nmod|response response|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentrations|compound|start_entity examines|nmod|concentrations examines|dobj|administration administration|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 neutralization|nmod|start_entity response|nmod|neutralization facilitate|nmod|response defenses|acl:relcl|facilitate defenses|nmod|levels levels|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 atorvastatin|nmod|start_entity switching|nmod|atorvastatin option|nsubj|switching option|acl|reduce reduce|dobj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 levels|compound|start_entity solution|nmod|levels filaments|nmod|solution binding|nmod|filaments -rsb-|amod|binding course|nmod|-rsb- measured|dobj|course measured|dep|ratios ratios|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 role|nmod|start_entity repair|dep|role promote|dobj|repair promote|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptors|compound|start_entity expressions|nmod|receptors end_entity|nmod|expressions 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 reductions|nmod|start_entity associated|nmod|reductions associated|nsubjpass|reductions reductions|nmod|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 increased|nsubj|start_entity increased|advcl|resulting resulting|nmod|reduction reduction|nmod|resistance resistance|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 proteins|compound|start_entity sub-family|nmod|proteins sub-family|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 0.000000 0 increased|parataxis|start_entity increased|ccomp|implicated implicated|nsubjpass|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 3.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 saturation|nmod|start_entity stabilized|nsubj|saturation stabilized|dobj|protein protein|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 using|nmod|start_entity using|nmod|cells cells|dep|end_entity 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 8.000000 0 0.000000 0 1.000000 0 0.000000 0 administration|nmod|start_entity produced|nsubj|administration produced|dobj|decrease decrease|nmod|sites sites|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 rate|nmod|start_entity rate|dep|ml ml|nmod|therapy therapy|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 therapy|compound|start_entity variants|nmod|therapy variants|nsubj|roles roles|nmod|end_entity 1.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 production|compound|start_entity oil|nmod|production effects|nmod|oil characterize|dobj|effects characterize|nmod|infusion infusion|nmod|saline saline|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|amod|start_entity more|nsubj|uptake more|advcl|obtained obtained|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|acl|start_entity resulted|nmod|levels biosynthesis|acl:relcl|resulted shifted|nmod|biosynthesis shifted|nsubjpass|balance balance|nmod|activities activities|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 dismutase|amod|start_entity presence|nmod|dismutase +|nmod|presence +|nmod|reduction reduction|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 lipids|compound|start_entity metabolism|nmod|lipids metabolic_defects|nmod|metabolism leads|nmod|metabolic_defects presence|acl:relcl|leads identify|dobj|presence identify|nsubj|levels levels|nmod|phosphorylation phosphorylation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 dose|nmod|start_entity induced|nmod|dose release|acl|induced release|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 exposed|xcomp|start_entity neurons|acl|exposed modulate|nmod|neurons modulate|dobj|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 decreased|nsubj|start_entity decreased|dobj|elaboration elaboration|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 trajectories|nmod|start_entity modify|dobj|trajectories modify|nsubj|variations variations|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 acting|nmod|start_entity potent|xcomp|acting potent|nsubj|ranitidine ranitidine|amod|end_entity 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8-bromo-camp|compound|start_entity increased|nsubj|8-bromo-camp increased|advcl|suggesting suggesting|ccomp|plays plays|dobj|role role|nmod|induction induction|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 cavity|amod|start_entity faced|nmod|cavity faced|advcl|occupied occupied|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 treatment|nmod|start_entity improved|nmod|treatment improved|nsubj|inhibitor inhibitor|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 2.000000 0 9.000000 0 0.000000 0 0.000000 0 0.000000 0 tolerance|compound|start_entity remains|nsubj|tolerance remains|advmod|long long|dep|adequate adequate|xcomp|overcome overcome|dobj|resistance resistance|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 used|xcomp|start_entity used|xcomp|assess assess|dobj|potential potential|nmod|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibited|nmod|start_entity inhibited|dobj|transients transients|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 act|dep|start_entity act|advcl|blocking blocking|dobj|action action|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 3.000000 0 4.000000 0 0.000000 0 1.000000 0 0.000000 0 nonselective|amod|start_entity inhibited|nsubj|nonselective inhibited|xcomp|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 nutrient|amod|start_entity nutrient|appos|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 8.000000 0 18.000000 0 2.000000 0 2.000000 0 1.000000 0 utilization|compound|start_entity regulated|nsubjpass|utilization regulated|nmod|translocation translocation|nmod|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 17.000000 0 5.000000 0 0.000000 0 sucrose|compound|start_entity sucrose|acl:relcl|used used|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 generation|nmod|start_entity proximal|nmod|generation events|amod|proximal localized|nmod|events localized|nsubj|development development|nmod|antagonism antagonism|nmod|actions actions|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 effect|nmod|start_entity study|dobj|effect study|advcl|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 increase|nsubj|start_entity increase|dobj|level level|nmod|end_entity 0.000000 0 2.000000 0 0.000000 0 1.000000 0 2.000000 0 8.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 independence|amod|start_entity associated|nsubjpass|independence associated|nmod|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 oxidation|compound|start_entity effects|nmod|oxidation effects|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 destroys|nsubj|start_entity destroys|advcl|interfering interfering|nmod|action action|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 species|compound|start_entity effects|nmod|species limiting|dobj|effects detoxifies|advcl|limiting enzyme|acl:relcl|detoxifies enzyme|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 review|nmod|start_entity review|dep|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 12.000000 0 0.000000 0 0.000000 0 0.000000 0 hydrolysis|nsubj|start_entity increased|dep|hydrolysis shown|ccomp|increased shown|nmod|experiments experiments|acl|carried carried|nmod|atpase atpase|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 mrnas|compound|start_entity found|nmod|mrnas found|nsubjpass|decrease decrease|nmod|end_entity 0.000000 0 0.000000 0 14.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 species|compound|start_entity species|dep|comparison comparison|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity patients|nmod|levels had|nsubj|patients had|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 production|amod|start_entity factors|nmod|production factors|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 formation|amod|start_entity formation|nmod|activation activation|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 intolerant|xcomp|start_entity patients|acl:relcl|intolerant evaluate|nmod|patients evaluate|dobj|effect effect|nmod|granulocyte-macrophage_colony-stimulating_factor granulocyte-macrophage_colony-stimulating_factor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 repair|amod|start_entity involves|dobj|repair machinery|acl:relcl|involves associated|nmod|machinery associated|nsubjpass|suppressor suppressor|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 prevention|compound|start_entity dependent|nsubj|prevention dependent|nmod|receptor receptor|compound|end_entity 0.000000 0 0.000000 0 19.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 structures|compound|start_entity -|dep|structures end_entity|dep|- 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 theophylline|compound|start_entity derivatives|nmod|theophylline containing|dobj|derivatives solutions|acl|containing incubation|nmod|solutions modify|nsubj|incubation modify|dobj|effects effects|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 ratio|compound|start_entity cpr|nmod|ratio showed|nsubj|cpr showed|nmod|values values|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 muramyl_dipeptide|appos|start_entity sensing|dobj|muramyl_dipeptide triggers|advcl|sensing triggers|nsubj|end_entity 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 a23187|compound|start_entity addition|nmod|a23187 alter|nmod|addition alter|nmod|conditions conditions|acl:relcl|abrogated abrogated|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 actions|nmod|start_entity considered|nmod|actions considered|nsubjpass|inactivation inactivation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 activity|nmod|start_entity responsible|nmod|activity believed|xcomp|responsible epoxide_glycidamide|acl:relcl|believed oxidized|nmod|epoxide_glycidamide oxidized|nmod|cytochrome_p4502e1 cytochrome_p4502e1|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 removes|xcomp|start_entity treatment|acl:relcl|removes treatment|nmod|cells cells|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 received|nmod|start_entity patients|acl:relcl|received associated|nmod|patients associated|nsubjpass|expression expression|nmod|excision_repair_cross-complementation_group-1 excision_repair_cross-complementation_group-1|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitor|appos|start_entity effects|nmod|inhibitor tested|dobj|effects tested|advcl|investigate investigate|dobj|role role|nmod|angiotensin-converting_enzyme angiotensin-converting_enzyme|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 4.000000 0 15.000000 0 0.000000 0 2.000000 0 1.000000 0 accumulations|nmod|start_entity peptide|dep|accumulations peptide|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 damage|compound|start_entity protection|nmod|damage provides|dobj|protection rationale|dep|provides investigate|advcl|rationale investigate|dobj|recovery recovery|compound|correlation correlation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 channel|compound|start_entity regulated|nmod|channel regulated|nsubjpass|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 supplementation|compound|start_entity resulted|nsubj|supplementation associated|advcl|resulted associated|nsubjpass|supplementation supplementation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 have|nsubj|start_entity have|dobj|effects effects|nmod|release release|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 production|compound|start_entity lack|nmod|production due|nmod|lack due|nsubj|attenuation attenuation|nmod|effect effect|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 glutathione|dep|start_entity antioxidants|appos|glutathione antioxidants|acl|associated associated|advcl|suspending suspending|dobj|activity activity|nmod|enzymes enzymes|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 epidermal_growth_factor_receptor|amod|start_entity exert|nsubj|epidermal_growth_factor_receptor exert|dobj|activity activity|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 1.000000 0 7.000000 0 3.000000 0 13.000000 0 0.000000 0 1.000000 0 0.000000 0 fraction|nmod|start_entity transport|nmod|fraction mediates|dobj|transport mediates|nsubj|monocarboxylate_transporter_1 monocarboxylate_transporter_1|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 uptake|nmod|start_entity action|nmod|uptake determined|nsubjpass|action determined|advcl|elucidate elucidate|dobj|effect effect|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 9.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 inhibitor|nsubj|start_entity inhibitor|nmod|kinase kinase|appos|breakpoint_cluster_region-abelson breakpoint_cluster_region-abelson|appos|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 2.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 compare|nmod|start_entity reported|advcl|compare reported|nsubj|nsaid nsaid|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 2.000000 0 14.000000 0 0.000000 0 0.000000 0 0.000000 0 output|compound|start_entity inhibit|dobj|output inhibit|nmod|activation activation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 aglycone|compound|start_entity treatment|nmod|aglycone led|nsubj|treatment led|nmod|activation activation|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 genes|compound|start_entity homologous|nmod|genes homologous|nsubj|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 affinity|amod|start_entity increases|dobj|affinity increases|dep|increases increases|nsubj|flurazepam flurazepam|nmod|addition addition|acl|facilitating facilitating|dobj|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 addition|nmod|start_entity affected|nmod|addition diminished|advcl|affected diminished|nsubjpass|activities activities|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 amiotransferases|appos|start_entity amiotransferases|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 phosphorylation/activation|compound|start_entity phosphorylation/activation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 challenged|nmod|start_entity challenged|dobj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 17.000000 0 0.000000 0 monitoring|compound|start_entity smoking|appos|monitoring perceived|nsubj|smoking perceived|nmod|addition addition|nmod|values values|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 levels|compound|start_entity associated|nmod|levels associated|nsubjpass|indices indices|compound|resistance resistance|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 exhibits|amod|start_entity m|nsubj|exhibits m|amod|affinity affinity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 level|nmod|start_entity exposed|nmod|level mice|acl|exposed /|dep|mice end_entity|dep|/ 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 treatment|compound|start_entity h|nsubj|treatment h|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 13.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 levels|amod|start_entity activity|nmod|levels inhibition|nmod|activity resulted|nmod|inhibition resulted|nsubj|inhibitor inhibitor|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 frequency|compound|start_entity same|nsubj|frequency same|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 sensors|compound|start_entity structure|nmod|sensors structure|dep|protein protein|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 functions|amod|start_entity role|nmod|functions role|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity controlled|dobj|levels investigation|dep|controlled investigation|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 17.000000 0 0.000000 0 rises|nmod|start_entity occur|nsubj|rises occur|nmod|hypoglycaemia hypoglycaemia|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 induce|nsubj|start_entity induce|dobj|hepatocyte_growth_factor hepatocyte_growth_factor|dep|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 accumulation|compound|start_entity assays|nmod|accumulation revealed|nsubj|assays revealed|nmod|transfectants transfectants|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 mg/kg|nmod|start_entity differ|nmod|mg/kg differ|nmod|groups groups|nmod|blockade blockade|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 induces|nsubj|start_entity identified|xcomp|induces target|acl|identified target|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 stimuli|nmod|start_entity generalize|nmod|stimuli generalize|nsubj|effects effects|nmod|inhibition inhibition|nmod|induction induction|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 test|compound|start_entity using|nmod|test presented|advcl|using presented|nsubjpass|procedure procedure|nmod|estimation estimation|nmod|release release|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 receptors|compound|start_entity clustering|nmod|receptors cause|dobj|clustering cause|nsubj|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 elicits|nsubj|start_entity elicits|nmod|conservation conservation|nmod|end_entity 4.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|acl|signaling signaling|advcl|regulating regulating|dobj|activity activity|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 normal|dep|start_entity normal|nmod|presence presence|nmod|levels levels|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 leucovorin|nummod|start_entity those|nmod|leucovorin achieves|nmod|those achieves|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pool|amod|start_entity enlarge|nsubj|pool enlarge|advcl|change change|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 4.000000 0 0.000000 0 2.000000 0 asct2|amod|start_entity receptor|nsubj|asct2 receptor|nmod|group group|acl:relcl|display display|dobj|events events|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 formation|compound|start_entity inhibition|nmod|formation attenuates|nmod|inhibition attenuates|nsubj|dyskinesia dyskinesia|appos|study study|acl|aimed aimed|advcl|investigating investigating|advcl|change change|dobj|expression expression|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 formation|nmod|start_entity effect|nmod|formation effect|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 8.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 dehydrogenase|amod|start_entity serum|dep|dehydrogenase factors|appos|serum factors|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 enhancement|nmod|start_entity biosynthesis|nsubj|enhancement biosynthesis|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 analysis|nmod|start_entity protease|nsubj|analysis protease|dobj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 chain|compound|start_entity released|nsubjpass|chain released|nmod|alpha-ketobutyrate alpha-ketobutyrate|acl:relcl|metabolized metabolized|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 epigallocatechin-3-gallate|appos|start_entity mechanism|nmod|epigallocatechin-3-gallate study|dobj|mechanism study|nmod|transition transition|acl|induced induced|nmod|protein protein|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 treated|nmod|start_entity hepatocytes|acl|treated observed|nmod|hepatocytes sites|amod|observed sites|nsubj|effect effect|nmod|induction induction|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 importance|nmod|start_entity importance|acl|determining determining|nmod|receptors receptors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 protons|dep|start_entity sensor|nmod|protons functions|nmod|sensor pathway|acl:relcl|functions neurons|nmod|pathway expressed|nmod|neurons expressed|nsubjpass|trpv1 trpv1|appos|end_entity 5.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 binding|nsubj|start_entity binding|nmod|receptors receptors|nummod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 associations|nmod|start_entity assessment|nmod|associations use|nsubj|assessment use|nmod|concentration concentration|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 targeting|dobj|start_entity strategies|acl|targeting effective|nsubj|strategies effective|advcl|measured measured|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 induced|nsubj|start_entity induced|dobj|degradation degradation|nmod|proteins proteins|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 leucine|nmod|start_entity augments|nsubj|leucine augments|dobj|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 10.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 amyloid-b|nmod|start_entity suppression|acl|amyloid-b suppression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 cotreatment|nmod|start_entity cotreatment|appos|inhibitor inhibitor|nmod|induction induction|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|amod|controlled controlled|nmod|glargine glargine|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 therapy|amod|start_entity independent|nsubj|therapy independent|xcomp|indicating indicating|ccomp|benefit benefit|nmod|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 0.000000 0 forms|nmod|start_entity presence|nmod|forms presence|dep|+ +|appos|no2 no2|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 free|nsubj|start_entity free|nmod|alterations alterations|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|dobj|synthesis synthesis|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 10.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 excursions|compound|start_entity reduction|nmod|excursions accompanied|nmod|reduction accompanied|nsubjpass|levels levels|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 effect|nmod|start_entity investigated|nsubjpass|effect investigated|advcl|investigate investigate|ccomp|inhibit inhibit|nsubj|inhibitor inhibitor|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 thyrotropin-releasing_hormone|appos|start_entity caused|nsubj|thyrotropin-releasing_hormone caused|nmod|concentration concentration|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitor|appos|start_entity prevented|nsubj|inhibitor prevented|advcl|suggesting suggesting|ccomp|requires requires|dobj|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 10.000000 0 0.000000 0 0.000000 0 0.000000 0 reduced|nsubj|start_entity reduced|advcl|indicating indicating|ccomp|alters alters|dobj|stability stability|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity maintained|nsubjpass|levels maintained|nmod|hormones hormones|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 contact|compound|start_entity interaction|nmod|contact interaction|nmod|control control|nmod|rna rna|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 showed|nsubj|start_entity showed|dobj|inhibition inhibition|nmod|phosphorylation phosphorylation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthesis|compound|start_entity force|nmod|synthesis generate|dobj|force generate|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 kinase|amod|start_entity activity|nmod|kinase evaluation|appos|activity carcass|nsubj|evaluation carcass|ccomp|conducted conducted|xcomp|investigate investigate|dobj|effects effects|nmod|immunization immunization|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 quinones|nmod|start_entity involved|dobj|quinones involved|nsubjpass|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 dose|nmod|start_entity exceeded|nmod|dose signal|acl:relcl|exceeded signal|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 7.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 start_entity|acl|observed observed|nmod|islets islets|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 blockade|compound|start_entity provided|nmod|blockade important|advcl|provided important|xcomp|establish establish|ccomp|provide provide|nsubj|interventions interventions|acl|targeting targeting|advcl|linking linking|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentration|nmod|start_entity decrease|dep|concentration supplemented|dep|decrease supplemented|nsubj|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 induced|nsubj|start_entity increased|advcl|induced increased|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 addicts|compound|start_entity normal|nmod|addicts normal|nsubj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|nmod|start_entity inhibits|nsubj|treatment inhibits|dep|enhances enhances|dobj|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 /|appos|start_entity superoxide_dismutase|appos|/ superoxide_dismutase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 binding|compound|start_entity influence|nmod|binding based|nmod|influence based|nsubjpass|mechanism mechanism|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 correlate|compound|start_entity mediated|nmod|correlate mediated|nsubj|unassigned unassigned|dep|fibroblast_growth_factor_21 fibroblast_growth_factor_21|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 3-kinase|amod|start_entity activated|nsubjpass|3-kinase activated|nmod|breast_cancers breast_cancers|amod|due due|nmod|mutations mutations|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transporter|compound|start_entity increase|dobj|transporter increase|nsubj|activation activation|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 4.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 potent|nmod|start_entity form|parataxis|potent form|nsubj|receptors receptors|compound|end_entity 2.000000 0 0.000000 0 4.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 regulation|nmod|start_entity affect|dobj|regulation affect|advcl|altering altering|nmod|parathyroid_hormone parathyroid_hormone|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 8.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 suggest|xcomp|start_entity suggest|advcl|paralleled paralleled|nmod|performance performance|nmod|mice mice|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 enantiomers|amod|start_entity effects|nmod|enantiomers quantify|dobj|effects quantify|nsubj|pharmacokinetics pharmacokinetics|nmod|metoprolol metoprolol|nmod|metabolizers metabolizers|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 induced|nmod|start_entity vivo|acl|induced end_entity|nmod|vivo 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 injection|compound|start_entity change|nmod|injection change|nsubj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 tolerance|compound|start_entity subjects|nmod|tolerance obtained|nmod|subjects those|acl|obtained returned|nmod|those determine|ccomp|returned quantified|advcl|determine quantified|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 dysfunction|amod|start_entity came|nsubj|dysfunction proved|ccomp|came proved|xcomp|antagonists antagonists|nmod|dopamine_d2_receptor dopamine_d2_receptor|appos|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 delivery|nmod|start_entity leading|nmod|delivery leading|dep|mice mice|amod|higher higher|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 receptors|amod|start_entity stimulation|nmod|receptors evoked|nmod|stimulation responses|acl|evoked contribute|nmod|responses contribute|nsubj|receptors receptors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 fasting|dobj|start_entity activity|acl|fasting activity|amod|endothelin-1 endothelin-1|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 species|nmod|start_entity conversion|nmod|species catalyzes|dobj|conversion catalyzes|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 inhibitor|amod|start_entity inhibitor|dep|ester ester|acl:relcl|altered altered|nsubjpass|decreases decreases|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 inhibitors|amod|start_entity inhibitors|nmod|therapy therapy|nmod|non-small_cell_lung_cancer non-small_cell_lung_cancer|amod|end_entity 0.000000 0 0.000000 0 7.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 activation|nmod|start_entity confer|dobj|activation confer|nsubj|elements elements|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 enhanced|nsubj|start_entity enhanced|dobj|uptake uptake|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|xcomp|examine examine|dobj|relation relation|nmod|end_entity 0.000000 0 2.000000 0 0.000000 0 1.000000 0 2.000000 0 2.000000 0 13.000000 0 0.000000 0 1.000000 0 0.000000 0 drinking|dobj|start_entity drinking|nmod|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 vanilloids|nmod|start_entity potent|nsubj|vanilloids potent|dobj|agonists agonists|amod|end_entity 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|compound|start_entity rate|nmod|uptake correlate|nsubj|rate correlate|nmod|number number|nmod|receptors receptors|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 investigated|nsubjpass|start_entity investigated|xcomp|using using|advcl|lacking lacking|dobj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthesis|compound|start_entity step|nmod|synthesis catalyzes|dobj|step enzyme|acl:relcl|catalyzes cyclooxygenase|appos|enzyme isoform|nmod|cyclooxygenase isoform|nsubj|cyclooxygenase-2 cyclooxygenase-2|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 preference|nmod|start_entity transporter|nmod|preference transporter|nsubj|dmt1 dmt1|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 nifedipine|amod|start_entity insensitive|nmod|nifedipine pathway|acl:relcl|insensitive promoted|nmod|pathway promoted|dobj|entry entry|nmod|+ +|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 conductance|compound|start_entity investigating|nmod|conductance cause|advcl|investigating implications|acl:relcl|cause implications|nmod|mutations mutations|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 start_entity|nsubj|complications complications|nmod|antagonists antagonists|compound|end_entity 0.000000 0 3.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 8.000000 0 0.000000 0 2.000000 0 0.000000 0 preincubation|nmod|start_entity inhibit|nsubj|preincubation inhibit|dobj|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 charged|xcomp|start_entity negatively|acl|charged end_entity|nmod|negatively 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitors|amod|start_entity displayed|nsubj|inhibitors interest|ccomp|displayed interest|nmod|view view|nmod|similarity similarity|nmod|protein protein|amod|activating activating|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 induced|nmod|start_entity response|acl|induced %|nmod|response producing|dobj|% doses|acl|producing comparison|nmod|doses revealed|nsubj|comparison revealed|dobj|activation activation|nmod|mescaline mescaline|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|dobj|concentrations concentrations|nmod|inhibition inhibition|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 6.000000 0 0.000000 0 1.000000 0 0.000000 0 effect|nmod|start_entity establish|dobj|effect sequenced|advcl|establish sequenced|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 buffered|nsubjpass|start_entity is|advcl|buffered is|nsubj|production production|amod|carbon_dioxide carbon_dioxide|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|acl|activating activating|dobj|pka pka|ref|which phosphorylation|nsubj|which phosphorylation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 output|compound|start_entity rise|nmod|output correlation|nmod|rise was|nsubj|correlation was|advcl|measured measured|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 action|compound|start_entity importance|nmod|action indicated|dobj|importance indicated|nsubj|descriptions descriptions|acl|leading leading|xcomp|complete complete|nmod|mice mice|acl|lacking lacking|dobj|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 exhibited|nsubj|start_entity exhibited|nmod|p-glycoprotein p-glycoprotein|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 naproxen|dep|start_entity some|appos|naproxen nonselective|nsubj|some selective|dep|nonselective selective|ccomp|selective selective|advmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 generate|dobj|start_entity generate|advmod|together together|nmod|ecto-5 ecto-5|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 deliveries|nmod|start_entity predicted|nsubjpass|deliveries predicted|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 consumption|compound|start_entity measured|nmod|consumption measured|nmod|relation relation|acl|serum serum|dobj|parathyroid_hormone parathyroid_hormone|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 18.000000 0 0.000000 0 adjuvant|nmod|start_entity respond|xcomp|adjuvant predict|ccomp|respond predict|nsubj|status status|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 affects|nsubj|start_entity suggesting|ccomp|affects mcf7|acl|suggesting mcf7|amod|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 treatment|amod|start_entity induces|nsubj|treatment induces|advcl|indicating indicating|ccomp|explain explain|dobj|differences differences|acl|observed observed|nmod|expression expression|nmod|induction induction|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 release|amod|start_entity change|nmod|release change|nsubj|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 blockade|nmod|start_entity attenuated|nsubj|blockade attenuated|advcl|did did|dobj|transfection transfection|nmod|construct construct|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 results|amod|start_entity administration|nmod|results observed|nsubj|administration observed|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 phosphatase|nsubj|start_entity phosphatase|dobj|pp2a pp2a|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|compound|start_entity regulators|nmod|metabolism known|xcomp|regulators factors|acl:relcl|known factors|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 response|compound|start_entity activation|nsubj|response activation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 indices|nmod|start_entity showed|nsubj|indices showed|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 4.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 l-lv|advcl|start_entity treatment|dep|l-lv treatment|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibited|nmod|start_entity had|parataxis|inhibited had|parataxis|accompanied accompanied|nmod|increase increase|nmod|contents contents|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 form|compound|start_entity form|nmod|end_entity 1.000000 0 0.000000 0 9.000000 0 1.000000 0 0.000000 0 16.000000 0 0.000000 0 9.000000 0 6.000000 0 0.000000 0 plays|nsubj|start_entity investigate|ccomp|plays investigate|dobj|association association|nmod|polymorphisms polymorphisms|amod|endometriosis endometriosis|nmod|estrogen_receptor_alpha estrogen_receptor_alpha|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 regimen|nmod|start_entity comparably|nmod|regimen performed|xcomp|comparably performed|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 protein|amod|start_entity rs10918594|nmod|protein association|nmod|rs10918594 association|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 3.000000 0 inhibited|nmod|start_entity inhibited|nsubjpass|activities activities|nmod|cyp2c9 cyp2c9|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 agent|dep|start_entity ai|nmod|agent combination|nmod|ai shown|nsubj|combination shown|nmod|+ +|appos|mbc mbc|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 2.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 generation|amod|start_entity effect|dep|generation effect|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 degradation|nmod|start_entity iron|nmod|degradation release|nmod|iron played|nsubj|release suggesting|ccomp|played occurred|xcomp|suggesting occurred|nsubj|upregulation upregulation|nmod|message message|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 administration|nmod|start_entity resulted|nsubj|administration resulted|nmod|inhibition inhibition|nmod|activity activity|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 assayed|nmod|start_entity nadh|advcl|assayed nadh|nsubj|e3s sensitive|nsubj|e3s sensitive|advcl|sensitive sensitive|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 decreased|nsubj|start_entity decreased|xcomp|lipopolysaccharide lipopolysaccharide|dep|up-regulation up-regulation|nmod:npmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|amod|start_entity inhibited|dobj|effect depended|advcl|inhibited depended|nsubj|release release|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 mtorc1|nmod|start_entity mtor|nmod|mtorc1 knockdown|nmod|mtor increases|nsubj|knockdown increases|advcl|suggesting suggesting|dobj|cross-talk cross-talk|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 8.000000 0 18.000000 0 2.000000 0 2.000000 0 1.000000 0 agents|nmod|start_entity shown|nmod|agents shown|nmod|inhibitors inhibitors|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 disposal|compound|start_entity disposal|acl|using using|dobj|infusions infusions|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 inhibited|nmod|start_entity electricus|ccomp|inhibited electricus|nsubj|effect effect|nmod|suckling suckling|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptor|compound|start_entity regulate|nsubj|receptor regulate|dobj|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 30.000000 0 0.000000 0 intakes|compound|start_entity effects|nmod|intakes regulated|dobj|effects regulated|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 induced|nmod|start_entity diabetes|acl|induced stabilized|nsubjpass|diabetes stabilized|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 synthesis|amod|start_entity step|dep|synthesis mediate|xcomp|step enzymes|acl:relcl|mediate enzymes|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 status|amod|start_entity wt|nmod|status lower|advcl|wt lower|nsubj|number number|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolites|compound|start_entity mediators|nmod|metabolites airways|nmod|mediators airways|nsubj|guinea_pig guinea_pig|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|nmod|period period|dep|associated associated|nmod|increase increase|nmod|staining staining|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitor|appos|start_entity nf-kb|dobj|inhibitor nf-kb|dobj|upregulation upregulation|nmod|activation activation|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity reduces|dobj|levels reduces|advcl|upregulating upregulating|dobj|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 phosphatase|nsubj|start_entity phosphatase|ccomp|generated generated|dobj|mutations mutations|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity inhibit|nsubj|treatment inhibit|dobj|activation activation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 transport|amod|start_entity play|nmod|transport distribution|acl:relcl|play protein|nmod|distribution protein|nsubj|fatty_acid-binding_protein_3 fatty_acid-binding_protein_3|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 vesicle|amod|start_entity end_entity|appos|vesicle 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 gene|amod|start_entity gene|appos|ct ct|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 line|appos|start_entity line|acl:relcl|heterozygous heterozygous|nmod|adenine_phosphoribosyltransferase adenine_phosphoribosyltransferase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 drugs|amod|start_entity starting|dobj|drugs suggests|advcl|starting suggests|dobj|testing testing|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 changed|nsubjpass|start_entity changed|nmod|infusion infusion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 gene|amod|start_entity polymorphism|nmod|gene located|nsubjpass|polymorphism located|nmod|centers centers|nmod|enzyme enzyme|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 8.000000 0 deprivation|compound|start_entity leads|nsubj|deprivation examined|advcl|leads examined|dobj|impact impact|nmod|knockdown knockdown|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 start_entity|nmod|face face|nmod|protein protein|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 regulated|nmod|start_entity regulated|nsubjpass|release release|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 encodes|nmod|start_entity gene|acl:relcl|encodes gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 monophosphate|appos|start_entity ,5|dep|monophosphate increasing|dobj|,5 sildenafil|acl|increasing sildenafil|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 catabolism|amod|start_entity regulate|dobj|catabolism serve|advcl|regulate supports|ccomp|serve supports|nsubj|addition addition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 generation|compound|start_entity focused|dobj|generation focused|nmod|glucose-6-phosphate_dehydrogenase glucose-6-phosphate_dehydrogenase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 sulfoxide|appos|start_entity metabolite|nsubj|sulfoxide metabolite|nmod|aldehyde_dehydrogenase aldehyde_dehydrogenase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 triglyceride|compound|start_entity correlate|nmod|triglyceride correlate|advmod|moderately moderately|advcl|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 derivatives|compound|start_entity agents|nsubj|derivatives agents|nmod|gamma gamma|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 l-glutamine|appos|start_entity transporter|nmod|l-glutamine acts|nmod|transporter acts|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 effectiveness|nmod|start_entity correlated|nsubj|effectiveness correlated|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 enzyme|nmod|start_entity synthesis|amod|enzyme expression|appos|synthesis expression|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 incorporation|nmod|start_entity intensity|nmod|incorporation studied|nmod|intensity studied|nsubjpass|sensitivity sensitivity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 10.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 level|nmod|start_entity increased|nsubjpass|level increased|nmod|/ /|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 element|amod|start_entity element|acl:relcl|located located|nmod|promoter promoter|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 osimertinib|appos|start_entity osimertinib|appos|tki tki|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 system|amod|start_entity state|nmod|system effect|nmod|state brought|nsubjpass|effect brought|parataxis|decreases decreases|nmod|drop drop|nmod|activity activity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 concentration|compound|start_entity change|nmod|concentration applied|nmod|change adjustments|acl|applied increased|nmod|adjustments increased|nsubj|concentration concentration|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 drugs|appos|start_entity forms|nmod|drugs interaction|nmod|forms cytochromes|nsubj|interaction cytochromes|ccomp|examined examined|nsubjpass|p450 p450|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 accept|xcomp|start_entity determines|advcl|accept determines|nsubj|part part|nmod|protein protein|dep|ala94-met418 ala94-met418|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 proportion|nmod|start_entity metabolized|nsubjpass|proportion metabolized|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 consumption|compound|start_entity stimulates|nsubj|consumption stimulates|dobj|production production|nmod|fibroblast_growth_factor_23 fibroblast_growth_factor_23|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 loading|compound|start_entity measured|nmod|loading measured|dobj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 doses|nmod|start_entity utilized|nsubjpass|doses avoided|advcl|utilized avoided|nsubjpass|saturation saturation|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 stores|compound|start_entity causing|dobj|stores hereditary_hemochromatosis|acl|causing found|nmod|hereditary_hemochromatosis found|nsubjpass|mutations mutations|nmod|class class|dep|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 export|nmod|start_entity inhibition|nmod|export results|nsubj|inhibition results|xcomp|suggesting suggesting|dobj|distribution distribution|nmod|results results|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 influx|compound|start_entity inhibited|dobj|influx inhibited|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 8.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 compounds|compound|start_entity kinetics|nmod|compounds kinetics|dep|pig pig|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effluxes|dobj|start_entity effluxes|nmod|cells cells|nmod|atp-binding_cassette_transporter_1 atp-binding_cassette_transporter_1|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 10.000000 0 3.000000 0 0.000000 0 activity|acl|start_entity methods|dep|activity determined|nsubjpass|methods determined|xcomp|using using|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 production|compound|start_entity period|nmod|production representative|nmod|period representative|nsubj|post-natally post-natally|appos|immuno-expression immuno-expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effects|nmod|start_entity dependent|nsubj|effects presented|ccomp|dependent presented|nsubj|treatment treatment|nmod|vsmcs vsmcs|nmod|blocker blocker|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 involves|dobj|start_entity involves|nsubj|differentiation differentiation|nmod|cells cells|acl|induced induced|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|dep|start_entity triggered|nmod|treatment activity|acl|triggered activity|dep|immortalized immortalized|ccomp|measured measured|xcomp|inhibit inhibit|xcomp|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity consistent|nmod|effects enhances|nsubj|consistent enhances|dobj|immunoreactivity immunoreactivity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity contribute|nmod|effect contribute|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 3.000000 0 3.000000 0 0.000000 0 1.000000 0 0.000000 0 o2|compound|start_entity o2|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 antagonists|compound|start_entity use|nmod|antagonists showed|nsubj|use showed|advcl|increased increased|nsubj|use use|nmod|inhibitors inhibitors|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 secretion|compound|start_entity mediate|dobj|secretion cells|acl:relcl|mediate expressed|nmod|cells expressed|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 1.000000 0 0.000000 0 46|amod|start_entity phosphorylated|nmod|46 phosphorylated|dobj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 treatment|compound|start_entity inhibited|nsubj|treatment dependent|advcl|inhibited dependent|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 2.000000 0 4.000000 0 1.000000 0 0.000000 0 0.000000 0 specificity|amod|start_entity agreement|nsubj|specificity agreement|nmod|support support|nmod|involvement involvement|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 addition|nmod|start_entity seen|nmod|addition dependent|advcl|seen dependent|advcl|induced induced|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 acts|nsubj|start_entity acts|nmod|agonist agonist|nmod|receptor receptor|appos|g_protein-coupled_receptor_55 g_protein-coupled_receptor_55|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receive|dobj|start_entity randomized|xcomp|receive randomized|advcl|test test|ccomp|predict predict|nsubj|response response|acl|angiotensin_converting_enzyme angiotensin_converting_enzyme|dobj|inhibition inhibition|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity mediated|nsubjpass|effect indicating|ccomp|mediated prevent|advcl|indicating prevent|nsubj|blockade blockade|nmod|end_entity 1.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 release|amod|start_entity secretagogue|nmod|release induced|advcl|secretagogue induced|nmod|protein protein|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 metabolism|nmod|start_entity involved|nmod|metabolism effects|acl|involved effects|nmod|enzymes enzymes|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 expansion|amod|start_entity altered|nmod|expansion protein|acl|altered end_entity|appos|protein 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 start_entity|dobj|phosphorylation phosphorylation|nmod|emt emt|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transport|compound|start_entity examined|nmod|transport examined|dobj|effects effects|nmod|affinity affinity|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 disease|amod|start_entity spinocerebellar_ataxia_type_3|appos|disease responsible|nmod|spinocerebellar_ataxia_type_3 protein|amod|responsible represents|nsubj|protein represents|advmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 index|compound|start_entity calculation|appos|index calculation|nmod|ratio ratio|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 production|amod|start_entity neutrophils|nmod|production primes|dobj|neutrophils primes|nsubj|tumor_necrosis_factor_alpha tumor_necrosis_factor_alpha|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 formation|nmod|start_entity showed|nmod|formation showed|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 nicotinamide_adenine_dinucleotide_phosphate|appos|start_entity controls|dep|nicotinamide_adenine_dinucleotide_phosphate reductase|acl:relcl|controls reductase|nsubj|thioredoxin thioredoxin|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 attenuated|nsubj|start_entity attenuated|nmod|expression expression|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 1.000000 0 1.000000 0 1.000000 0 0.000000 0 levels|amod|start_entity values|nmod|levels values|dep|increases increases|nmod|levels levels|nmod|levels levels|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 lipid|amod|start_entity role|nmod|lipid investigated|dobj|role investigated|nmod|regulation regulation|nmod|gene gene|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transforms|nmod|start_entity transforms|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 4.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 receptors|compound|start_entity sensitivity|nmod|receptors determinant|nmod|sensitivity determinant|nsubj|subunit subunit|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pathway|amod|start_entity acting|nmod|pathway enzyme|acl|acting activity|appos|enzyme activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 release|compound|start_entity reducing|nmod|release toxin|acl|reducing toxin|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 utilization|compound|start_entity inhibit|dobj|utilization blunted|parataxis|inhibit blunted|dobj|hyperglycemia hyperglycemia|acl|caused caused|nmod|injection injection|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 accumulation|nmod|start_entity leading|nmod|accumulation cause|advcl|leading cause|dobj|decrease decrease|nmod|activity activity|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 2.000000 0 1.000000 0 observed|nmod|start_entity observed|nsubj|reversibility reversibility|nmod|reaction reaction|acl|catalyzed catalyzed|nmod|purified purified|amod|dependent dependent|ccomp|studied studied|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 absorption|compound|start_entity regulate|dobj|absorption appears|xcomp|regulate peptide|acl:relcl|appears end_entity|appos|peptide 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 11.000000 0 0.000000 0 4.000000 0 12.000000 0 1.000000 0 synthase|amod|start_entity inos|appos|synthase -lsb-|dep|inos -lsb-|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 agents|nmod|start_entity confers|nmod|agents confers|nsubj|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 methionine80|nmod|start_entity end_entity|nmod|methionine80 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 stimulation|amod|start_entity combination|nmod|stimulation mediated|nmod|combination mediated|nsubjpass|control control|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 flux|amod|start_entity regulation|nmod|flux regulation|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 activity|nmod|start_entity described|dobj|activity described|parataxis|inhibitor inhibitor|nsubj|epidermal_growth_factor_receptor epidermal_growth_factor_receptor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 receptors|compound|start_entity analyzed|nsubjpass|receptors c-erbb-2|ccomp|analyzed c-erbb-2|nsubj|mechanisms mechanisms|nmod|carcinogenesis carcinogenesis|appos|expression expression|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 nitro-l-arginine_methyl_ester|amod|start_entity nitro-l-arginine_methyl_ester|appos|inhibitor inhibitor|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 10.000000 0 0.000000 0 2.000000 0 0.000000 0 derivatives|amod|start_entity tetradecylthioacetic_acid|acl:relcl|derivatives activators|nsubj|tetradecylthioacetic_acid activators|nmod|glucocorticoid_receptor glucocorticoid_receptor|dep|chimaera chimaera|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effects|nmod|start_entity support|nsubj|effects support|advcl|modify modify|nsubj|selectivity selectivity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nmod|secretion secretion|acl|induced induced|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 efflux|nmod|start_entity promote|dobj|efflux apolipoproteins|xcomp|promote called|dep|apolipoproteins called|nsubj|atp_binding_cassette_transporter_a-1 atp_binding_cassette_transporter_a-1|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 10.000000 0 3.000000 0 0.000000 0 start_entity|amod|binding binding|dep|protein protein|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 start_entity|parataxis|present present|nsubj|and_amphetamine-regulated_transcript and_amphetamine-regulated_transcript|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 responses|amod|start_entity mediate|dobj|responses mediate|nsubj|channels channels|acl|comprised comprised|nmod|subunits subunits|amod|end_entity 0.000000 0 0.000000 0 10.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 containing|dep|start_entity end_entity|acl|containing 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 i.p.|amod|start_entity tetralin|appos|i.p. tetralin|amod|end_entity 2.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 conveys|advcl|start_entity conveys|nsubj|heterodimer heterodimer|nmod|ahr ahr|appos|end_entity 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptor|compound|start_entity cellular|nmod|receptor cellular|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transporter|amod|start_entity expression|nmod|transporter occurs|nsubj|expression occurs|nmod|core core|nmod|rats rats|acl|withdrawn withdrawn|advcl|upregulates upregulates|nsubj|treatment treatment|appos|antibiotic antibiotic|acl|shown shown|xcomp|increase increase|dobj|expression expression|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 13.000000 0 0.000000 0 1.000000 0 nac|compound|start_entity using|dobj|nac examined|advcl|using examined|nsubjpass|role role|nmod|species species|nmod|mediators mediators|nmod|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 proteins|compound|start_entity proteins|dep|associated associated|nmod|tissue tissue|acl:relcl|abundant abundant|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 production|compound|start_entity deficiency|nmod|production impact|nmod|deficiency determined|dobj|impact determined|advcl|depriving depriving|dobj|patients patients|nmod|treatment treatment|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 cells|nmod|start_entity treatment|nmod|cells sensitized|nsubj|treatment sensitized|advcl|promoting promoting|dobj|accumulation accumulation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 9.000000 0 0.000000 0 2.000000 0 0.000000 0 25-hydroxyvitamin_d|amod|start_entity 25-hydroxyvitamin_d|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effect|nmod|start_entity examined|dobj|effect examined|nmod|induction induction|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 driven|nmod|start_entity support|acl:relcl|driven support|dep|given given|dep|antagonism antagonism|nmod|subunit subunit|compound|end_entity 0.000000 0 0.000000 0 15.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 1.000000 0 0.000000 0 domain|amod|start_entity mutations|nmod|domain activating|dobj|mutations epidermal_growth_factor_receptor|acl|activating epidermal_growth_factor_receptor|appos|end_entity 0.000000 0 0.000000 0 7.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 sensitive|nmod|start_entity sensitive|advcl|resistant resistant|nsubj|line line|compound|end_entity 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 abolished|nmod|start_entity abolished|xcomp|indicating indicating|dobj|involvement involvement|nmod|receptors receptors|nummod|end_entity 1.000000 0 3.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 g|dep|start_entity g|dobj|equ equ|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 e.g.|dep|start_entity drugs|appos|e.g. compete|nsubj|drugs compete|dep|pump pump|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 line|nmod|start_entity line|xcomp|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 reverses|nsubj|start_entity reverses|dobj|deficits deficits|nmod|downregulation downregulation|nmod|expression expression|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 7.000000 0 8.000000 0 16.000000 0 1.000000 0 5.000000 0 0.000000 0 administered|nmod|start_entity administered|nmod|mice mice|dep|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 17.000000 0 0.000000 0 administration|compound|start_entity greater|nmod|administration greater|nsubj|increase increase|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 variation|nmod|start_entity coefficient|nmod|variation ranged|nsubj|coefficient ranged|nmod|group group|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 residues|amod|start_entity play|nsubj|residues inhibiting|advcl|play inhibiting|xcomp|binding binding|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 load|compound|start_entity collected|nmod|load samples|acl|collected determined|nmod|samples determined|nsubjpass|levels levels|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 substrates|amod|start_entity displays|nmod|substrates displays|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 adjustments|amod|start_entity range|nmod|adjustments value|nmod|range bring|dobj|value bring|xcomp|using using|xcomp|testing testing|nsubj|vn-p2y12 vn-p2y12|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 species|compound|start_entity scavenging|dobj|species maintain|advcl|scavenging superfamilies|dep|maintain superfamilies|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 oxidation|compound|start_entity reduction|nmod|oxidation mechanism|nsubj|reduction mechanism|nmod|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 attenuation|nmod|start_entity end_entity|dep|attenuation 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 measurement|nmod|start_entity tested|nmod|measurement tested|nmod|addition addition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 action|compound|start_entity mediator|nmod|action gper|nmod|mediator reveals|dobj|gper reveals|nsubj|lack lack|nmod|effects effects|nmod|tissues tissues|nmod|mice mice|compound|end_entity 1.000000 0 0.000000 0 6.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 receptors|amod|start_entity receptors|nmod|types types|appos|end_entity 0.000000 0 0.000000 0 12.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 fingers|compound|start_entity contains|dobj|fingers protein|acl:relcl|contains predicts|dobj|protein reported|dep|predicts reported|nsubj|proteins proteins|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 start_entity|nsubj|inhibition inhibition|nmod|blocks blocks|amod|end_entity 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 mass|nmod|start_entity increased|nsubj|mass increased|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 dehydrogenase|dep|start_entity dehydrogenase|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 treated|nmod|start_entity hrecs|acl|treated thymidine|advcl|hrecs thymidine|dobj|levels levels|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 0.000000 0 2.000000 0 3.000000 0 0.000000 0 expression|nmod|start_entity inducibility|nmod|expression eliminated|nsubjpass|inducibility eliminated|nmod|motifs motifs|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 doses|nmod|start_entity alter|nsubj|doses alter|dobj|sensitivity sensitivity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity antagonized|nsubjpass|effect antagonized|nmod|nan-190 nan-190|compound|receptor receptor|nummod|end_entity 2.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 trafficking|compound|start_entity regulates|dobj|trafficking regulates|nsubj|activity activity|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 agent|nsubj|start_entity agent|acl:relcl|targets targets|nmod|family family|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 reported|nmod|start_entity treatment|acl:relcl|reported produced|nsubj|treatment produced|nmod|animals animals|acl|associated associated|nmod|down-regulation down-regulation|nummod|end_entity 3.000000 0 0.000000 0 10.000000 0 1.000000 0 0.000000 0 4.000000 0 1.000000 0 3.000000 0 1.000000 0 0.000000 0 ability|nmod|start_entity due|nmod|ability interest|amod|due attracted|dobj|interest attracted|nsubj|g-protein-coupled_estrogen_receptor_1 g-protein-coupled_estrogen_receptor_1|dep|formerly formerly|compound|end_entity 1.000000 0 0.000000 0 6.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 influx|compound|start_entity engage|nmod|influx based|xcomp|engage pathways|acl|based neuronal|nmod|pathways highlight|advcl|neuronal highlight|dobj|contribution contribution|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 antibodies|nmod|start_entity using|dobj|antibodies immunocytochemistry|acl|using combined|nmod|immunocytochemistry combined|advcl|determine determine|ccomp|produce produce|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 variations|compound|start_entity stabilize|dobj|variations tend|xcomp|stabilize tend|advcl|buffering buffering|dobj|swings swings|nmod|concentrations concentrations|nmod|injections injections|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 release|compound|start_entity have|nsubj|release have|dobj|correlation correlation|nmod|increases increases|nmod|activity activity|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 treatment|compound|start_entity receiving|dobj|treatment patients|acl|receiving correlate|nmod|patients associated|advcl|correlate associated|nsubjpass|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|compound|start_entity mediate|nmod|uptake mediate|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 reduction|amod|start_entity rate|nmod|reduction measuring|dobj|rate observed|advcl|measuring observed|nsubj|increase increase|nmod|activity activity|nmod|presence presence|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthesis|amod|start_entity augmented|nsubjpass|synthesis augmented|nmod|cleavage cleavage|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 orally|compound|start_entity administration|nmod|orally examine|nmod|administration examine|dobj|changes changes|nmod|concentrations concentrations|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 17.000000 0 0.000000 0 fxr|amod|start_entity downregulation|nmod|fxr leads|nmod|downregulation leads|dobj|effect effect|nmod|gw4064 gw4064|compound|end_entity 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 channel|compound|start_entity bears|nsubj|channel bears|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 11.000000 0 0.000000 0 0.000000 0 metabolism|compound|start_entity regulator|nmod|metabolism confirmed|nmod|regulator confirmed|ccomp|involved involved|advcl|regulating regulating|dobj|degradation degradation|nmod|divalent_metal_transporter_1 divalent_metal_transporter_1|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 7.000000 0 2.000000 0 0.000000 0 produces|dobj|start_entity enzyme|acl:relcl|produces enzyme|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 forms|nmod|start_entity regulation|dep|forms regulation|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 18.000000 0 0.000000 0 lapatinib|amod|start_entity lapatinib|nummod|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 release|compound|start_entity inhibitory|nmod|release due|xcomp|inhibitory suggests|ccomp|due suggests|nsubj|absence absence|nmod|effect effect|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 inhibit|nsubj|start_entity inhibit|dobj|production production|nmod|interferon-gamma interferon-gamma|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|compound|start_entity divalent_metal_transporter_1|dep|uptake divalent_metal_transporter_1|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 7.000000 0 2.000000 0 0.000000 0 intake|compound|start_entity decrease|nmod|intake caused|nsubj|decrease caused|dobj|elevation elevation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 18.000000 0 0.000000 0 biosynthesis|compound|start_entity enzyme|nmod|biosynthesis aromatase|appos|enzyme target|nsubj|aromatase target|nmod|therapy therapy|nmod|estrogen_receptor estrogen_receptor|appos|end_entity 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transporter|compound|start_entity size|compound|transporter size|amod|dopamine dopamine|nmod:npmod|increases increases|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 3.000000 0 channels|compound|start_entity activation|nmod|channels induces|nsubj|activation induces|dobj|release release|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 bound|nsubj|start_entity bound|nmod|subunit subunit|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 biosynthesis|amod|start_entity enzyme|nmod|biosynthesis ornithine_decarboxylase|nsubj|enzyme ornithine_decarboxylase|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 phosphatase|nsubj|start_entity phosphatase|xcomp|dephosphorylating dephosphorylating|dobj|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 start_entity|dep|mg/kg mg/kg|dep|-rsb- -rsb-|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 7.000000 0 8.000000 0 16.000000 0 1.000000 0 5.000000 0 0.000000 0 kinase|amod|start_entity kinase|acl|signaling signaling|dobj|pathways pathways|nmod|those those|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 ptk|nmod|start_entity blocking|dobj|ptk abolished|csubj|blocking abolished|nmod|oocytes oocytes|acl|injected injected|nmod|cd63 cd63|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolite|nmod|start_entity binds|nsubj|metabolite binds|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 amp|appos|start_entity 1/cyclic|dep|amp stimulated|dobj|1/cyclic stimulated|nmod|parathyroid_hormone parathyroid_hormone|nmod|receptor receptor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 release|compound|start_entity did|nmod|release did|advcl|suggesting suggesting|ccomp|inhibits inhibits|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 interfere|nsubj|start_entity interfere|advcl|acting acting|nmod|inhibitors inhibitors|nmod|enzymes enzymes|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 leads|nmod|start_entity leads|nsubj|decrease decrease|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 identifying|dobj|start_entity identifying|nmod|activator activator|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 _|amod|start_entity release|nmod|_ increase|dobj|release increase|nsubj|analog analog|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 content|compound|start_entity resulting|nmod|content sphingosine_kinase_1|acl|resulting sphingosine_kinase_1|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 administering|dobj|start_entity shown|advcl|administering shown|xcomp|result result|nmod|reduction reduction|nmod|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentration|compound|start_entity increased|nsubj|concentration increased|ccomp|fell fell|dep|+ +|parataxis|0.87 0.87|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 superfamily|amod|start_entity family|nmod|superfamily member|nmod|family end_entity|appos|member 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 exchange|nmod|start_entity exchange|nmod|presence presence|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|nmod|start_entity caused|nmod|levels hepatotoxicity|acl|caused preventing|dobj|hepatotoxicity play|advcl|preventing play|nsubj|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 output|amod|start_entity stimulation|nmod|output stimulation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 agonists|ccomp|start_entity agonists|nsubj|injections injections|nmod|end_entity 2.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 monophosphate|dep|start_entity np_receptor_a|amod|monophosphate np_receptor_a|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 assay|compound|start_entity detectable|nmod|assay detectable|nsubj|2b 2b|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 mg|compound|start_entity receive|dobj|mg receive|nsubj|hypercholesterolemia hypercholesterolemia|dep|> >|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effect|nmod|start_entity understand|dobj|effect understand|nsubj|detection detection|nmod|estrogen_receptor estrogen_receptor|appos|end_entity 1.000000 0 0.000000 0 5.000000 0 2.000000 0 0.000000 0 7.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 start_entity|acl:relcl|interfered interfered|nmod|inhibition inhibition|nmod|phosphorylation phosphorylation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 kinase|compound|start_entity expression|nmod|kinase expression|appos|end_entity 0.000000 0 0.000000 0 16.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 inhibits|nsubj|start_entity inhibits|dobj|hydroxylation hydroxylation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|compound|start_entity showed|nmod|uptake showed|nsubj|cells cells|acl|transduced transduced|nmod|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 23.000000 0 2.000000 0 1.000000 0 reduction|nmod|start_entity activates|nsubj|reduction activates|dobj|factors factors|acl:relcl|regulate regulate|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 start_entity|nsubj|findings findings|acl:relcl|elevated elevated|dobj|levels levels|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 function|nmod|start_entity gsk-3|nmod|function impact|nmod|gsk-3 remains|nsubj|impact remains|advcl|identified identified|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transmission|amod|start_entity reduce|dobj|transmission blocking|advcl|reduce blocking|dobj|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 administered|ccomp|start_entity patients|acl|administered was|nmod|patients was|advcl|fasting fasting|dobj|concentrations concentrations|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 oxidation|compound|start_entity estimates|nmod|oxidation provided|dobj|estimates provided|nmod|infusion infusion|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 enhanced|nsubj|start_entity enhanced|dobj|tumor tumor|acl|promoting promoting|nmod|secretion secretion|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 2.000000 0 1.000000 0 5.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 production|compound|start_entity stimulate|dobj|production inability|acl|stimulate due|nmod|inability due|nsubj|internalization internalization|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 dependence|compound|start_entity history|nmod|dependence suppress|dep|history suppress|nsubj|increases increases|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 remained|nsubj|start_entity remained|nmod|concentrations concentrations|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 activity|amod|start_entity regulates|dobj|activity regulates|advcl|suggesting suggesting|ccomp|event event|nsubj|alterations alterations|nmod|metabolism metabolism|nmod|deprivation deprivation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 deliver|dobj|start_entity show|ccomp|deliver show|advcl|known known|nsubjpass|delivery delivery|nmod|iron iron|nmod|cells cells|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 treatment|amod|start_entity accompanied|nsubjpass|treatment accompanied|nmod|up-regulation up-regulation|nmod|end_entity 6.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 advances|amod|start_entity inhibition|nmod|advances inhibition|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 administration|compound|start_entity suppressed|nmod|administration suppressed|nsubjpass|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 gnrha|compound|start_entity administration|nmod|gnrha administration|dep|des-gly des-gly|acl:relcl|increased increased|dobj|mrna mrna|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 demonstrated|nmod|start_entity demonstrated|nsubj|raltitrexed raltitrexed|appos|inhibitor inhibitor|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 3.000000 0 3.000000 0 0.000000 0 1.000000 0 0.000000 0 -rsb-|compound|start_entity -rsb-|dep|-rsb- -rsb-|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 18.000000 0 0.000000 0 iii|compound|start_entity recommends|nsubj|iii recommends|ccomp|consider consider|dobj|cholesterol cholesterol|nmod|marker marker|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 channel|compound|start_entity occurring|nsubj|channel occurring|nmod|gene gene|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 15.000000 0 3.000000 0 1.000000 0 therapy|compound|start_entity serum|nmod|therapy serum|dobj|insulin insulin|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 mutant|amod|start_entity using|dobj|mutant confirmed|advcl|using confirmed|ccomp|independent independent|nsubj|signalling signalling|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 toxicity|nmod|start_entity mediates|dobj|toxicity factor|acl:relcl|mediates factor|nsubj|aryl_hydrocarbon_receptor aryl_hydrocarbon_receptor|appos|end_entity 3.000000 0 0.000000 0 3.000000 0 2.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 +|compound|start_entity mediates|dobj|+ mediates|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 gonadotropins|amod|start_entity end_entity|appos|gonadotropins 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 existed|nmod|start_entity existed|nmod|induction induction|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 supply|compound|start_entity restoration|nmod|supply potentiates|nsubj|restoration potentiates|nmod|effect effect|acl:relcl|sensitive sensitive|nmod|inhibition inhibition|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 different|nsubj|start_entity different|nmod|antagonists antagonists|amod|end_entity 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 peptide|amod|start_entity crh|appos|peptide includes|dobj|crh includes|nsubj|family family|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 potency|amod|start_entity reduce|dobj|potency reduce|nsubj|most most|dep|studied studied|xcomp|morphine morphine|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 phosphorylation|amod|start_entity abolished|dobj|phosphorylation abolished|nmod|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 have|nsubj|start_entity have|nmod|activation activation|nmod|end_entity 6.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 inhibits|nsubj|start_entity inhibits|nmod|inhibition inhibition|nmod|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 accumulation|appos|start_entity level|appos|accumulation studied|dobj|level studied|nmod|receptor receptor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 start_entity|acl|dosing dosing|advcl|genotype genotype|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 transport|amod|start_entity explore|nmod|transport aimed|xcomp|explore aimed|advcl|inhibited inhibited|nsubjpass|transport transport|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 action|nmod|start_entity mediated|nsubjpass|action mediated|nmod|receptor receptor|appos|progesterone_receptor progesterone_receptor|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 anion|amod|start_entity secretion|nmod|anion increased|dobj|secretion modify|advcl|increased modify|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 consequence|nmod|start_entity atherosclerosis|nmod|consequence synthesis|amod|atherosclerosis progression|nmod|synthesis described|nsubjpass|progression investigated|advcl|described investigated|dobj|correlation correlation|nmod|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 5.000000 0 2.000000 0 10.000000 0 gene|amod|start_entity overexpression|compound|gene overexpression|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 antagonists|amod|start_entity ability|nmod|antagonists ability|acl|stimulate stimulate|dobj|release release|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 15.000000 0 0.000000 0 0.000000 0 14.000000 0 0.000000 0 levels|compound|start_entity correlated|nmod|levels correlated|nsubjpass|levels levels|compound|end_entity 0.000000 0 0.000000 0 5.000000 0 8.000000 0 1.000000 0 124.000000 0 0.000000 0 14.000000 0 220.000000 0 1.000000 0 amino_acids|appos|start_entity regulate|nsubj|amino_acids regulate|nmod|end_entity 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 abolished|nsubj|start_entity abolished|advcl|introduced introduced|xcomp|block block|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transport|nmod|start_entity mediates|dobj|transport mediates|nsubj|end_entity 0.000000 0 0.000000 0 8.000000 0 1.000000 0 2.000000 0 24.000000 0 1.000000 0 109.000000 0 35.000000 0 1.000000 0 species|compound|start_entity production|nsubj|species reducing|xcomp|production protect|advcl|reducing protect|nsubj|overexpression overexpression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 subunit|nmod|start_entity encoding|dobj|subunit gene|acl|encoding rfa1|appos|gene displayed|nsubj|rfa1 displayed|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 ornithine_decarboxylase|amod|start_entity levels|nmod|ornithine_decarboxylase reduction|nmod|levels due|dep|reduction due|nmod|consequences consequences|nmod|inhibition inhibition|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 absence|nmod|start_entity coincides|advcl|absence coincides|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 biosynthesis|compound|start_entity enzyme|nmod|biosynthesis odc|appos|enzyme induced|nsubjpass|odc kinase|ccomp|induced kinase|nsubj|mechanisms mechanisms|acl|involved involved|nmod|induction induction|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 resistance|amod|start_entity risk|nmod|resistance methylation|nmod|risk methylation|nsubj|association association|nmod|dna dna|compound|end_entity 0.000000 0 3.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 8.000000 0 0.000000 0 2.000000 0 0.000000 0 effects|acl|start_entity blocked|nsubjpass|effects blocked|advcl|suggesting suggesting|ccomp|requires requires|dobj|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 activity|compound|start_entity oscillations|nmod|activity reflecting|dobj|oscillations potential|acl|reflecting oscillations|nmod|potential respond|nmod|oscillations respond|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 transport|compound|start_entity impaired|nsubj|transport conditions|acl:relcl|impaired occurs|nmod|conditions signal|acl|occurs signal|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 eluting|amod|start_entity introduced|nsubjpass|eluting introduced|nmod|reactor reactor|acl|containing containing|dobj|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 2.000000 0 2.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|acl|activated activated|advcl|leading leading|xcomp|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 markedly|compound|start_entity increases|nsubj|markedly increases|dobj|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity revert|dobj|effect revert|nmod|end_entity 4.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 metabolite|appos|start_entity responsible|nmod|metabolite responsible|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 activity|nmod|start_entity compare|dobj|activity compare|nmod|untreated_breast_cancer untreated_breast_cancer|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 supplementation|nmod|start_entity shown|nmod|supplementation dependent|advcl|shown dependent|nsubj|activity activity|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 cultivated|amod|start_entity addition|nmod|cultivated showed|nsubj|addition showed|ccomp|reduced reduced|nsubjpass|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 formed|nsubj|start_entity formed|nmod|clusters clusters|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 embolism|compound|start_entity complication|nsubj|embolism complication|advcl|minimized minimized|nmod|awareness awareness|nmod|problem problem|appos|monitoring monitoring|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 oxidized|nmod|start_entity revealed|advcl|oxidized revealed|nsubj|analysis analysis|nmod|keap1 keap1|appos|repressor repressor|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 due|nmod|start_entity regeneration|amod|due levels|nmod|regeneration maintain|dobj|levels failure|acl|maintain results|nsubj|failure results|nmod|glucose-6-phosphate_dehydrogenase glucose-6-phosphate_dehydrogenase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity downregulates|nsubj|treatment downregulates|dobj|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 7.000000 0 2.000000 0 0.000000 0 activities|nmod|start_entity end_entity|compound|activities 0.000000 0 0.000000 0 4.000000 0 0.000000 0 2.000000 0 2.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 levels|amod|start_entity related|nmod|levels related|nsubjpass|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 reabsorption|compound|start_entity mediated|nmod|reabsorption mediated|nsubj|administration administration|nmod|mice mice|acl|resulted resulted|nmod|decrease decrease|nmod|levels levels|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 8.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 receptor|compound|start_entity known|nmod|receptor end_entity|dep|known 3.000000 0 0.000000 0 15.000000 0 1.000000 0 0.000000 0 4.000000 0 1.000000 0 3.000000 0 1.000000 0 0.000000 0 release|nmod|start_entity mechanism|nmod|release participating|nmod|mechanism participating|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 pressure|compound|start_entity found|nmod|pressure found|parataxis|found found|nmod|values values|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 reduced|nsubj|start_entity reduced|advcl|showed showed|nsubj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 13.000000 0 0.000000 0 transduction|compound|start_entity transduction|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 5.000000 0 2.000000 0 10.000000 0 effect|compound|start_entity mimicked|nsubjpass|effect mimicked|nmod|forskolin forskolin|nmod|dpcpx dpcpx|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 peroxidase|amod|start_entity levels|amod|peroxidase levels|amod|reduced_glutathione reduced_glutathione|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 oxidation|amod|start_entity involved|nmod|oxidation expressed|advcl|involved expressed|advcl|scarce scarce|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 did|nsubj|start_entity attenuated|advcl|did attenuated|dobj|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 basal|nmod|start_entity /|dep|basal rate|dep|/ rate|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 injury|compound|start_entity unlikely|nsubj|injury suggest|ccomp|unlikely suggest|nsubj|results results|dep|end_entity 0.000000 0 0.000000 0 14.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 production|amod|start_entity suppressing|dobj|production result|advcl|suppressing result|nsubj|use use|nmod|inhibitors inhibitors|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 assess|advcl|start_entity assess|nmod|response response|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 replace|dobj|start_entity replace|nsubj|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 generation|nmod|start_entity leads|nmod|generation catabolism|acl:relcl|leads enzyme|nmod|catabolism enzyme|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity studied|dobj|effect studied|nmod|mediator mediator|appos|factor factor|acl:relcl|degraded degraded|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2,3-dioxygenases|amod|start_entity 2,3-dioxygenases|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 effect|nmod|start_entity responsible|nmod|effect responsible|nsubj|affinity affinity|acl|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 utilization|nmod|start_entity synthesis|nmod|utilization examined|nsubjpass|synthesis examined|nmod|preparations preparations|acl|supplemented supplemented|nmod|nadp nadp|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 area|nmod|start_entity applied|nmod|area applied|nsubj|effects effects|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 pretreatment|nmod|start_entity blunted|nsubj|pretreatment blunted|dobj|enhancement enhancement|nmod|release release|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 clearance|compound|start_entity confer|nmod|clearance confer|nsubj|efficiency efficiency|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 associated|nmod|start_entity outcomes|acl|associated predictor|nmod|outcomes unclear|advcl|predictor unclear|nsubj|role role|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 output|compound|start_entity x|appos|output greater|nsubj|x greater|advcl|added added|nmod|infusion infusion|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 accumulated|xcomp|start_entity accumulated|nsubj|null-mutant null-mutant|nmod|arabidopsis arabidopsis|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 presence|nmod|start_entity possesses|nmod|presence protein|acl:relcl|possesses protein|dep|definition definition|nmod|neuropathy_target_esterase neuropathy_target_esterase|appos|esterase esterase|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 administration|nmod|start_entity increased|nsubj|administration phosphorylated|ccomp|increased phosphorylated|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptors|amod|start_entity have|nmod|receptors have|nsubj|receptors receptors|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibition|acl:relcl|start_entity prevents|nsubj|inhibition prevents|nmod|accumulation accumulation|nmod|peptide peptide|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity pronounced|nsubj|effect pronounced|nmod|period period|nmod|release release|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 lymphocytes|appos|start_entity conjugated|nsubj|lymphocytes conjugated|xcomp|containing containing|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 biosynthesis|amod|start_entity lipoprotein|nmod|biosynthesis effect|nmod|lipoprotein amplified|dobj|effect amplified|nsubj|insulin-like_growth_factor_i insulin-like_growth_factor_i|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 competition|nmod|start_entity determined|dobj|competition determined|ccomp|reduced reduced|nsubj|complexes complexes|acl|formed formed|nmod|antiandrogens antiandrogens|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity causing|dobj|levels analysis|acl|causing analysis|nmod|mutations mutations|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 concentration|nmod|start_entity increased|nmod|concentration increased|nsubjpass|secretion secretion|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 improves|nsubj|start_entity improves|parataxis|suggest suggest|ccomp|is is|iobj|antagonism antagonism|appos|end_entity 0.000000 0 1.000000 0 0.000000 0 1.000000 0 7.000000 0 3.000000 0 13.000000 0 0.000000 0 1.000000 0 0.000000 0 deactivates|nsubj|start_entity deactivates|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 oxidation|amod|start_entity increase|nmod|oxidation dependent|nsubj|increase dependent|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 reduced|nmod|start_entity reduced|advcl|undetectable undetectable|nsubj|levels levels|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 17.000000 0 0.000000 0 synthesis|compound|start_entity rate-limiting|nmod|synthesis support|ccomp|rate-limiting support|dep|uncoupling uncoupling|nmod|inhibition inhibition|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 element|compound|start_entity control|nmod|element transfected|nmod|control transfected|nsubjpass|end_entity 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 14.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 di-isopropyl_fluorophosphate|appos|start_entity injection|nmod|di-isopropyl_fluorophosphate induced|nmod|injection induced|nsubj|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|compound|start_entity regulate|dobj|metabolism regulate|nsubj|hormones hormones|nmod|analogue analogue|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|compound|start_entity adipokine|appos|uptake end_entity|appos|adipokine 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 13.000000 0 0.000000 0 production|compound|start_entity levels|nmod|production inhibition|nmod|levels enhanced|nmod|inhibition enhanced|dobj|production production|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 2.000000 0 1.000000 0 6.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 plays|nsubj|start_entity plays|dep|suppresses suppresses|nmod|brain brain|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 start_entity|nmod|subtype subtype|nummod|end_entity 0.000000 0 7.000000 0 2.000000 0 0.000000 0 1.000000 0 8.000000 0 4.000000 0 0.000000 0 4.000000 0 0.000000 0 kinases|nsubj|start_entity elicited|parataxis|kinases elicited|nmod|kinases kinases|nmod|family family|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 testing|nmod|start_entity provocative|acl|testing provocative|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 mechanisms|nmod|start_entity clarify|dobj|mechanisms examined|advcl|clarify examined|xcomp|using using|dobj|mice mice|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 alanine_aminotransferase|nsubj|start_entity alanine_aminotransferase|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|nmod|start_entity uptake|nsubj|aspect aspect|nmod|iron iron|amod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 induction|nmod|start_entity blocked|nsubjpass|induction blocked|advcl|insensitive insensitive|nsubj|activation activation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 addition|nmod|start_entity permitted|nsubj|addition permitted|dobj|adjustment adjustment|nmod|time time|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 markedly|appos|start_entity enhanced|nsubj|markedly enhanced|dobj|increase increase|nmod|activity activity|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 treatment|compound|start_entity influence|nmod|treatment influence|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 cytokines|amod|start_entity cytokines|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 modulated|nmod|start_entity modulated|nsubjpass|effect effect|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 15.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 reduction|nmod|start_entity relationship|nmod|reduction relationship|dep|reductase reductase|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 facilitator|compound|start_entity facilitator|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 e.g.|nmod|start_entity activation|acl|e.g. activation|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 levels|nmod|start_entity regulate|dobj|levels regulate|nmod|stimuli stimuli|nmod|basic_fibroblast_growth_factor basic_fibroblast_growth_factor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 able|nsubj|start_entity able|advcl|leads leads|nmod|induction induction|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 14alpha-demethylase|amod|start_entity 14alpha-demethylase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|advmod|there there|nmod|response response|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 proteins|compound|start_entity that|nmod|proteins resembles|xcomp|that resembles|nsubj|pattern pattern|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 pathway|dep|start_entity pathway|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 6.000000 0 0.000000 0 2.000000 0 0.000000 0 channel|compound|start_entity functioning|nmod|channel proteins|acl|functioning regulates|dobj|proteins regulates|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 15.000000 0 3.000000 0 1.000000 0 depended|nmod|start_entity depended|nsubj|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 _|appos|start_entity component|nmod|_ component|acl:relcl|exerts exerts|nmod|activation activation|nmod|type-1 type-1|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 affect|nsubj|start_entity affect|advcl|does does|nsubj|starvation starvation|dep|impairs impairs|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 2.000000 0 7.000000 0 1.000000 0 1.000000 0 1.000000 0 residues|amod|start_entity residues|nmod|domain domain|nmod|receptor receptor|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 trafficking|amod|start_entity regulate|dobj|trafficking regulate|nsubj|sumoylation sumoylation|nmod|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 activates|nsubj|start_entity suggesting|ccomp|activates transient|xcomp|suggesting transient|nmod|absence absence|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 content|compound|start_entity showed|nsubj|content showed|ccomp|caused caused|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 sensed|nsubjpass|start_entity suggesting|ccomp|sensed resulted|xcomp|suggesting resulted|nmod|expression expression|nmod|system system|acl|composed composed|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 kinase|amod|start_entity genistein|amod|kinase analogue|appos|genistein analogue|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 presence|appos|start_entity presence|nmod|nucleotide-binding_oligomerization_domain_2 nucleotide-binding_oligomerization_domain_2|appos|end_entity 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 biosynthesis|compound|start_entity intermediates|nsubj|biosynthesis intermediates|xcomp|induce induce|xcomp|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 role|nmod|start_entity assessment|nmod|role induced|nsubj|assessment induced|xcomp|using using|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 release|dobj|start_entity release|nsubj|cleaves cleaves|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 administration|compound|start_entity administration|nmod|phenotype phenotype|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity determine|dobj|levels examined|advcl|determine examined|dobj|data data|acl|taken taken|nmod|randomised randomised|acl|controlled controlled|nmod|therapy therapy|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 gene|compound|start_entity polymorphism|nmod|gene background|dep|polymorphism background|appos|end_entity 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 5.000000 0 catalyses|nmod|start_entity catalyses|nsubj|acid_sphingomyelinase acid_sphingomyelinase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 infusion|compound|start_entity relative|nmod|infusion caused|ccomp|relative caused|advcl|increase increase|nmod|output output|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 tetralin|amod|start_entity 8-hydroxy-2|dep|tetralin agonists|amod|8-hydroxy-2 effects|nmod|agonists examined|dobj|effects examined|nmod|receptor receptor|nummod|end_entity 2.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 synthesis|amod|start_entity regulation|nmod|synthesis controlled|nsubjpass|regulation controlled|nmod|level level|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 5.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 motifs|compound|start_entity deleted|nsubjpass|motifs mrnas|acl:relcl|deleted identified|dobj|mrnas identified|nmod|addition addition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 facilitate|nsubj|start_entity facilitate|dobj|interaction interaction|ccomp|induces induces|dobj|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 therapy|compound|start_entity beneficial|nsubj|therapy beneficial|nmod|treatment treatment|nmod|forms forms|nmod|resistance resistance|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 regulated|nmod|start_entity receptor|acl|regulated receptor|nsubj|peroxisome_proliferator-activated_receptor_gamma peroxisome_proliferator-activated_receptor_gamma|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 decrease|amod|start_entity accompanied|nsubjpass|decrease accompanied|nmod|decrease decrease|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 sensitivity|amod|start_entity predicting|dobj|sensitivity expression|acl|predicting expression|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 5.000000 0 12.000000 0 1.000000 0 0.000000 0 0.000000 0 tablet|amod|start_entity agent|nsubj|tablet agent|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 combination|nmod|start_entity associated|nmod|combination end_entity|acl|associated 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|appos|receptors receptors|nummod|end_entity 4.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 modulates|nsubj|start_entity modulates|advcl|expressing expressing|dobj|receptors receptors|nummod|end_entity 0.000000 0 0.000000 0 13.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 delivery|compound|start_entity activate|dobj|delivery activate|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 clearance|nmod|start_entity showed|dobj|clearance showed|nmod|plasma plasma|appos|levels levels|nmod|mrna mrna|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 neurons|amod|start_entity endocytosis|nmod|neurons promote|nmod|endocytosis promote|dobj|internalization internalization|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 3.000000 0 depletion|compound|start_entity relatable|nmod|depletion seems|xcomp|relatable seems|advcl|seems seems|nsubj|rhythm rhythm|nmod|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 had|nsubj|start_entity shown|advcl|had shown|xcomp|inhibit inhibit|dobj|activation activation|nmod|ability ability|acl|substitute substitute|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 transport|compound|start_entity inhibition|nmod|transport explains|dobj|inhibition mm|acl:relcl|explains inhibited|advcl|mm inhibited|dobj|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 17.000000 0 5.000000 0 0.000000 0 biosynthesis|amod|start_entity blockade|nmod|biosynthesis decreased|nsubj|blockade decreased|dobj|induction induction|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 modify|nsubj|start_entity modify|dobj|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 16.000000 0 0.000000 0 0.000000 0 10.000000 0 0.000000 0 affect|compound|start_entity affect|dep|ability ability|nmod|end_entity 1.000000 0 0.000000 0 5.000000 0 1.000000 0 0.000000 0 9.000000 0 0.000000 0 5.000000 0 3.000000 0 0.000000 0 treatment|nmod|start_entity decreased|nsubj|treatment decreased|advcl|affecting affecting|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 level|compound|start_entity days|nmod|level /|dep|days h.|acl:relcl|/ given|nmod|h. given|nsubjpass|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 test|compound|start_entity response|nmod|test abnormal|nsubj|response abnormal|nmod|discontinuation discontinuation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 17.000000 0 0.000000 0 pharmacokinetics|nmod|start_entity evaluated|nmod|pharmacokinetics evaluated|dobj|effect effect|nmod|genotype genotype|compound|end_entity 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 administration|compound|start_entity caused|nmod|administration caused|nmod|compression compression|nmod|presence presence|nmod|induction induction|amod|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 2.000000 0 2.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 synthesis|amod|start_entity involved|nmod|synthesis enzymes|acl|involved encoding|dobj|enzymes genes|acl|encoding deleted|nmod|genes strains|acl|deleted strains|appos|gsh2 gsh2|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 homeostasis|compound|start_entity pathology|nmod|homeostasis pathology|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 analysis|amod|start_entity similar|nsubj|analysis similar|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 antagonist|compound|start_entity inhibitor|nmod|antagonist inhibitor|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transporter|amod|start_entity activation|nmod|transporter activation|nsubj|control control|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 produced|nsubj|start_entity produced|ccomp|responsible responsible|nmod|stabilization stabilization|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 y-27632|dep|start_entity inhibitors|appos|y-27632 studies|nmod|inhibitors require|advcl|studies require|nsubj|activation activation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 4.000000 0 9.000000 0 0.000000 0 0.000000 0 0.000000 0 storage|nmod|start_entity express|nmod|storage express|dobj|histidine_decarboxylase histidine_decarboxylase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nsubj|properties properties|nmod|agonist agonist|appos|end_entity 4.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentration|nmod|start_entity inhibited|nmod|concentration inhibited|nsubjpass|phosphorylation phosphorylation|nmod|c-jun c-jun|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 3.000000 0 12.000000 0 0.000000 0 0.000000 0 0.000000 0 secretagogues|compound|start_entity secrete|nmod|secretagogues secrete|dobj|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 concentrations|nmod|start_entity effects|nmod|concentrations determine|dobj|effects aimed|xcomp|determine study|acl|aimed unassigned|dep|study unassigned|dep|expression expression|nmod|protein protein|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 circulating|dobj|start_entity related|advcl|circulating related|nmod|increase increase|nmod|estrogen_receptor estrogen_receptor|appos|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pyroglutamyl-seryl-glycinamide|appos|start_entity activity|nmod|pyroglutamyl-seryl-glycinamide releasing|dobj|activity growth_hormone|acl|releasing growth_hormone|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 responded|nmod|start_entity responded|nsubj|lines lines|nmod|background background|advmod|but but|nmod|levels levels|nmod|protein protein|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity discontinuation|nmod|treatment inhibit|nsubj|discontinuation inhibit|dobj|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|appos|molecule molecule|acl:relcl|interrupts interrupts|dobj|autophosphorylation autophosphorylation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 addition|nmod|start_entity demonstrated|nmod|addition demonstrated|nmod|inhibition inhibition|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 greater|amod|start_entity greater|nmod|administration administration|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 levels|nmod|start_entity balance|nmod|levels kinases|nsubj|balance kinases|dobj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 oxidation|amod|start_entity alcohol_dehydrogenase|dep|oxidation alcohol_dehydrogenase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 as|nmod|start_entity measure|advmod|as measure|dobj|inhibition inhibition|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 had|advmod|start_entity had|nsubj|end_entity 5.000000 0 0.000000 0 25.000000 0 0.000000 0 5.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 one|nsubj|start_entity one|nmod|treatments treatments|nmod|lung_cancer lung_cancer|acl|harboring harboring|dobj|mutation mutation|appos|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 5.000000 0 12.000000 0 1.000000 0 0.000000 0 0.000000 0 phosphodiesterase|compound|start_entity receptor|nmod|phosphodiesterase receptor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 channels|compound|start_entity channels|appos|dhpr dhpr|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 provided|nsubj|start_entity compounds|ccomp|provided compounds|nsubj|intervention intervention|nmod|rescue rescue|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthesis|compound|start_entity change|nmod|synthesis proportional|nmod|change proportional|nsubjpass|increase increase|nmod|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 increase|dobj|start_entity increase|nsubj|concentrations concentrations|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 responsiveness|compound|start_entity confer|dobj|responsiveness confer|nsubj|sequence sequence|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 formation|compound|start_entity contribute|nsubj|formation implied|ccomp|contribute contents|acl:relcl|implied contents|dep|activation activation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 identification|nmod|start_entity identification|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 drug|appos|start_entity resistant|nmod|drug resistant|nsubj|signaling signaling|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 therapy|amod|start_entity led|nsubj|therapy led|nmod|increase increase|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptors|amod|start_entity affected|nsubjpass|receptors assessed|advcl|affected assessed|dobj|expression expression|nmod|subunits subunits|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptor|amod|start_entity needed|nmod|receptor needed|nsubjpass|molecule molecule|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity levels|amod|active active|dep|immunoreactivity immunoreactivity|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 efflux|compound|start_entity caused|dobj|efflux caused|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 18.000000 0 0.000000 0 piperidinedicarboxylic_acid|amod|start_entity and/or|dobj|piperidinedicarboxylic_acid and/or|nsubj|tetrodotoxin tetrodotoxin|appos|receptor receptor|appos|end_entity 0.000000 0 0.000000 0 4.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 dissolved|dobj|start_entity similar|xcomp|dissolved weathering|ccomp|similar consumed|xcomp|weathering end_entity|acl|consumed 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 induces|nsubj|start_entity induces|dobj|resistance resistance|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 15.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 currents|compound|start_entity revealed|dobj|currents revealed|nsubj|recordings recordings|nmod|neurons neurons|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 enzymes|amod|start_entity levels|nmod|enzymes increase|nmod|levels steroid|nsubj|increase steroid|dobj|1 1|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 ability|nmod|start_entity indicates|nsubj|ability indicates|ccomp|involves involves|dobj|mechanism mechanism|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 species|compound|start_entity release|nmod|species sphingomyelinase|appos|release activation|nmod|sphingomyelinase followed|nmod|activation followed|nmod|stimulation stimulation|nmod|trafficking trafficking|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity unchanged|nsubj|levels showed|advcl|unchanged showed|nsubj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 retention|amod|start_entity consequences|nmod|retention counteracting|dobj|consequences arise|xcomp|counteracting felt|ccomp|arise felt|ccomp|gained gained|advcl|axis axis|nsubj|discovery discovery|nmod|klotho klotho|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 enzyme|compound|start_entity isoform|nmod|enzyme encoding|nmod|isoform expression|nmod|encoding expression|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 decarboxylase|amod|start_entity express|dobj|decarboxylase vectors|advcl|express vectors|dobj|gene gene|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 microspheres|compound|start_entity release|nmod|microspheres release|dobj|behavior behavior|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 healing|nmod|start_entity healing|dep|requirement requirement|nmod|mtor/akt2 mtor/akt2|nmod|activation activation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 stimulated|nmod|start_entity pbmc|acl|stimulated _|nmod|pbmc _|dobj|-2 -2|nmod|+ +|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 relationship|acl|start_entity relationship|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 suppress|nsubj|start_entity suppress|advcl|inhibiting inhibiting|advcl|express express|dobj|end_entity 3.000000 0 0.000000 0 10.000000 0 1.000000 0 0.000000 0 4.000000 0 1.000000 0 3.000000 0 1.000000 0 0.000000 0 inhibitors|amod|start_entity effective|nsubj|inhibitors effective|nmod|patients patients|nmod|resistance resistance|acl|resulting resulting|nmod|mutations mutations|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 dehydrogenase|compound|start_entity dehydrogenase|dep|1 1|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 resistant|advmod|start_entity facilitate|advcl|resistant facilitate|dobj|cells cells|amod|end_entity 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 cells|nmod|start_entity inhibitory|nmod|cells inhibitory|nmod|inhibitors inhibitors|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 glcnac|compound|start_entity transfers|dobj|glcnac o-glcnac_transferase|acl:relcl|transfers catalyzed|nmod|o-glcnac_transferase catalyzed|nsubjpass|modification modification|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 inhibitor|amod|start_entity inhibitor|acl:relcl|targets targets|dobj|receptor receptor|amod|end_entity 0.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 circulating|dobj|start_entity measured|advcl|circulating measured|nsubjpass|concentrations concentrations|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 2.000000 0 0.000000 0 62.000000 0 0.000000 0 6.000000 0 133.000000 0 0.000000 0 dfmo|amod|start_entity dfmo|appos|inhibitor inhibitor|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 levels|amod|start_entity effects|nmod|levels studied|nsubjpass|effects studied|advcl|verify verify|ccomp|affect affect|nsubj|level level|amod|angiotensin_converting_enzyme angiotensin_converting_enzyme|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 receptor-associated_protein|dep|start_entity receptor-associated_protein|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 status|compound|start_entity measures|nmod|status measures|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 kinase|nsubj|start_entity kinase|dobj|phosphorylates phosphorylates|nummod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 caused|nmod|start_entity caused|nmod|mutations mutations|acl:relcl|encodes encodes|dobj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 receptors|compound|start_entity activation|nmod|receptors activation|appos|receptors receptors|amod|end_entity 0.000000 0 0.000000 0 18.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 content|compound|start_entity regulated|nmod|content regulated|nsubjpass|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 inhibits|nsubj|start_entity inhibits|advcl|producing producing|nmod|efficacy efficacy|acl|paralleling paralleling|dobj|ability ability|acl|inhibit inhibit|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 oxidase|compound|start_entity assembly|nmod|oxidase limiting|dobj|assembly reduced|xcomp|limiting reduced|advcl|normal normal|nsubj|levels levels|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthase|amod|start_entity activation|amod|synthase activation|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 14.000000 0 4.000000 0 30.000000 0 prodrug|nsubj|start_entity prodrug|nmod|cp-734432 cp-734432|acl:relcl|stimulated stimulated|dobj|formation formation|nmod|cells cells|acl|expressing expressing|dobj|receptor receptor|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 stabilizing|dobj|start_entity counterion|acl|stabilizing contribute|nmod|counterion contribute|advcl|has has|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 diffusion|compound|start_entity limited|nmod|diffusion limited|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 therapy|amod|start_entity marker|nmod|therapy marker|nsubj|abundance abundance|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptors|compound|start_entity receptors|amod|homomeric homomeric|dep|end_entity 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity studied|dobj|effect studied|nmod|cycle cycle|acl|using using|dobj|mutant mutant|acl:relcl|has has|dobj|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 hs|appos|start_entity observed|nmod|hs changes|acl|observed adjusted|nmod|changes mrna|amod|adjusted up-regulated|nsubj|mrna up-regulated|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 mixtures|nmod|start_entity effects|dep|mixtures effects|nmod|mixtures mixtures|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 alpha|amod|start_entity repress|nsubj|alpha repress|advcl|inhibiting inhibiting|nmod|promoters promoters|acl|bearing bearing|dobj|receptor receptor|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 lipolysis|amod|start_entity lipolysis|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 antagonist|appos|start_entity studied|nmod|antagonist studied|dobj|role role|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 required|nsubjpass|start_entity required|nmod|production production|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 derivatives|compound|start_entity efficiency|nmod|derivatives tested|nsubjpass|efficiency tested|nmod|acetylcholinesterase acetylcholinesterase|appos|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 indicated|dobj|start_entity infants|dep|indicated found|nmod|infants found|xcomp|bear bear|nmod|degree degree|nmod|saturation saturation|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 start_entity|nsubj|assays assays|amod|specific specific|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 10.000000 0 0.000000 0 1.000000 0 0.000000 0 dose|compound|start_entity inhibited|nsubj|dose inhibited|dobj|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 thrombin|nmod|start_entity modification|acl|thrombin modification|nmod|mrna mrna|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 decreased|nmod|start_entity body|acl:relcl|decreased uninfluenced|nsubj|body uninfluenced|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 1.000000 0 0.000000 0 9.000000 0 0.000000 0 effect|nmod|start_entity mechanisms|nmod|effect searched|nmod|mechanisms searched|nmod|analyses analyses|acl:relcl|implicated implicated|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nmod|thyroxine thyroxine|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 levels|compound|start_entity increased|dobj|levels increased|nsubj|infusion infusion|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 synthesis|amod|start_entity triggered|dobj|synthesis triggered|advcl|ineffective ineffective|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 start_entity|appos|antidepressant antidepressant|acl:relcl|blocks blocks|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 associated|nmod|start_entity pial_dilation|acl:relcl|associated elicited|dobj|pial_dilation elicited|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 inhibits|amod|start_entity release|amod|inhibits release|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 spain|compound|start_entity cetrotide|dep|spain antagonist|dep|cetrotide antagonist|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity %|nmod|levels %|nmod|variance variance|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 17.000000 0 0.000000 0 removal|nmod|start_entity basal|nmod|removal returned|xcomp|basal level|acl:relcl|returned followed|nmod|level calcium|acl|followed resulted|nmod|calcium demonstrated|ccomp|resulted demonstrated|nsubj|microfluorimetry microfluorimetry|nmod|cells cells|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 homeostasis|compound|start_entity expression|nmod|homeostasis expression|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 11.000000 0 0.000000 0 4.000000 0 12.000000 0 1.000000 0 dissociates|nmod|start_entity dissociates|nsubj|end_entity 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 heme|xcomp|start_entity degrades|xcomp|heme degrades|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 turnover|compound|start_entity measured|dobj|turnover measured|nmod|patients patients|nmod|resistance resistance|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 achieved|advcl|start_entity achieved|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 imbalance|amod|start_entity associated|nmod|imbalance requirement|acl|associated contribute|nmod|requirement contribute|nsubj|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 related|nsubjpass|start_entity related|nmod|variation variation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 presence|nmod|start_entity arginine|nmod|presence response|nmod|arginine response|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 effects|nmod|start_entity resulted|nmod|effects resulted|nsubj|induction induction|nmod|expression expression|amod|end_entity 0.000000 0 0.000000 0 5.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 role|nmod|start_entity man|nmod|role evidence|nmod|man provides|dobj|evidence provides|nsubj|presence presence|nmod|secretion secretion|nmod|administration administration|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 p21|nmod|start_entity induction|nmod|p21 independent|nsubj|induction independent|advcl|lacking lacking|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 increases|compound|start_entity addition|nmod|increases end_entity|nmod|addition 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 1.000000 0 0.000000 0 alpha|compound|start_entity activated|nmod|alpha pathways|acl|activated pathways|appos|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 released|nsubjpass|start_entity released|nmod|response response|nmod|concentration concentration|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 receptor|compound|start_entity receptor|acl|using using|advcl|targeting targeting|dobj|subunit subunit|compound|end_entity 0.000000 0 0.000000 0 12.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 responded|xcomp|start_entity responded|xcomp|suggesting suggesting|ccomp|determinant determinant|nmod|responsiveness responsiveness|nmod|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 10.000000 0 0.000000 0 0.000000 0 0.000000 0 correlated|nmod|start_entity potent|parataxis|correlated potent|advcl|reducing reducing|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 pitavastatin|appos|start_entity efficacy|nmod|pitavastatin efficacy|appos|inhibitor inhibitor|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 ligands|nmod|start_entity binding|nmod|ligands possesses|nmod|binding possesses|nsubj|end_entity 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 norepinephrine|appos|start_entity uptake|nmod|norepinephrine examined|nmod|uptake examined|ccomp|contribute contribute|nmod|induction induction|nmod|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 investigated|nsubjpass|start_entity investigated|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 reduced|nsubj|start_entity reduced|advcl|increased increased|nmod|exposure exposure|appos|treatment treatment|nmod|inhibitor inhibitor|amod|end_entity 0.000000 0 2.000000 0 0.000000 0 1.000000 0 4.000000 0 4.000000 0 10.000000 0 0.000000 0 0.000000 0 0.000000 0 content|amod|start_entity investigated|nmod|content investigated|dobj|effect effect|nmod|imipramine imipramine|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 hydroxylase|amod|start_entity proto-oncogene|dep|hydroxylase proto-oncogene|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 potencies|nmod|start_entity determined|nsubjpass|potencies determined|nmod|desensitization desensitization|nmod|end_entity 0.000000 0 0.000000 0 10.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|amod|start_entity caused|nsubj|treatment caused|dobj|suppression suppression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 homeostasis|compound|start_entity extends|nmod|homeostasis implying|ccomp|extends alcohol|acl|implying properties|nmod|alcohol attenuates|dobj|properties attenuates|nsubj|signaling signaling|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 17.000000 0 0.000000 0 oxidase|dep|start_entity oxidase|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptor|amod|start_entity receptor|acl:relcl|derived derived|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 properties|nmod|start_entity investigated|nsubjpass|properties investigated|parataxis|inhibitors inhibitors|nsubj|angiotensin-converting_enzyme angiotensin-converting_enzyme|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 4.000000 0 15.000000 0 0.000000 0 2.000000 0 1.000000 0 hormones|amod|start_entity number|nmod|hormones regulated|nmod|number regulated|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 kinases|compound|start_entity family|nmod|kinases define|dobj|family define|nsubj|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 influence|nmod|start_entity influence|nmod|response response|acl|elicited elicited|nmod|endothelin-1 endothelin-1|appos|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 efflux|compound|start_entity role|nmod|efflux mediated|nsubjpass|role mediated|nmod|atp-binding_cassette_transporter_a1 atp-binding_cassette_transporter_a1|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 10.000000 0 3.000000 0 0.000000 0 start_entity|nmod|response response|nmod|d3 d3|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 18.000000 0 0.000000 0 repair|amod|start_entity role|nmod|repair plays|dobj|role complementing|acl:relcl|plays complementing|appos|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 modification|nmod|start_entity unmask|nsubj|modification unmask|dobj|antigens antigens|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 antagonist|appos|start_entity abolished|nmod|antagonist mediated|advcl|abolished mediated|nsubj|effects effects|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 accumulation|compound|start_entity greater|nsubj|accumulation greater|nmod|patients patients|nmod|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 2.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 odds|appos|start_entity nonalcoholic_steatohepatitis|dep|odds risk|nmod|nonalcoholic_steatohepatitis associated|nmod|risk associated|nsubjpass|a/a a/a|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 ethanediamine_dihydrochloride|appos|start_entity n|dep|ethanediamine_dihydrochloride n|amod|end_entity 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 stimulated|advmod|start_entity stimulated|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 levels|amod|start_entity affects|dobj|levels affects|nmod|predominates predominates|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 metabolism|compound|start_entity related|nmod|metabolism genes|acl|related polymorphisms|nmod|genes correlate|nsubj|polymorphisms correlate|nmod|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 induces|nsubj|start_entity show|advcl|induces show|ccomp|increase increase|dobj|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 cilexetil|compound|start_entity antagonist|nsubj|cilexetil antagonist|amod|end_entity 0.000000 0 3.000000 0 0.000000 0 0.000000 0 2.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 residues|amod|start_entity numbers|nmod|residues changes|nmod|numbers involved|nsubjpass|changes involved|advcl|increasing increasing|dobj|variability variability|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibits|nsubj|start_entity inhibits|dobj|synthesis synthesis|amod|17a-hydroxylase/17 17a-hydroxylase/17|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|compound|start_entity relationship|nmod|uptake examine|dobj|relationship evaluated|ccomp|examine evaluated|nmod|delivery delivery|nmod|levels levels|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 modulate|nsubj|start_entity modulate|dobj|expression expression|nmod|activation activation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 signal|dobj|start_entity binds|xcomp|signal binds|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 giving|nmod|start_entity exceeded|xcomp|giving become|xcomp|exceeded become|nsubj|capacity capacity|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 effect|compound|start_entity increase|nsubj|effect increase|xcomp|indicating indicating|dobj|inhibition inhibition|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 3.000000 0 0.000000 0 1.000000 0 0.000000 0 therapy|amod|start_entity cycles|nmod|therapy remained|nmod|cycles remained|xcomp|positive positive|nmod|transgene transgene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 synapses|amod|start_entity assess|nmod|synapses use|advcl|assess use|dobj|line line|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 nilutamide|dep|start_entity safety|appos|nilutamide safety|acl:relcl|performed performed|nmod|antagonists antagonists|compound|end_entity 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 showed|ccomp|start_entity showed|nsubj|activity activity|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity increases|nmod|levels evidenced|nmod|increases resulted|advcl|evidenced resulted|nmod|activation activation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 side-chain|advmod|start_entity activity|amod|side-chain activity|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 level|nmod|start_entity patients|nmod|level distinct|nmod|patients decreased|parataxis|distinct decreased|nsubjpass|activity activity|nmod|plasma plasma|appos|transferase transferase|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 delta_opioid_receptor|appos|start_entity delta_opioid_receptor|acl|signaling signaling|dep|induced induced|nmod|agonist agonist|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 dehydrogenase|amod|start_entity isozymes|nmod|dehydrogenase isozymes|appos|malate_dehydrogenase malate_dehydrogenase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 pha|compound|start_entity effect|nmod|pha studying|dobj|effect studying|nmod|expression expression|nmod|cytokines cytokines|dep|il-1_alpha il-1_alpha|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 derivative|nmod|start_entity unassigned|dep|derivative synthesized|nsubjpass|unassigned synthesized|advcl|targeting targeting|dobj|gastrin_releasing_peptide_receptor gastrin_releasing_peptide_receptor|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 weeks|nmod|start_entity ec|nmod|weeks cycles|nmod|ec treatment|dep|cycles treatment|nmod|trial trial|acl|having having|dobj|status status|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity correlation|nmod|effects was|nsubj|correlation was|nmod|induction induction|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 6.000000 0 0.000000 0 2.000000 0 2.000000 0 0.000000 0 nonanol|appos|start_entity nonanol|appos|inhibitor inhibitor|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 deposition|compound|start_entity displayed|dobj|deposition end_entity|acl:relcl|displayed 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 bioavailability|nmod|start_entity increased|dobj|bioavailability increased|nmod|content content|dep|increase increase|dep|increase increase|nmod|release release|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 11.000000 0 0.000000 0 4.000000 0 12.000000 0 1.000000 0 secretion|nmod|start_entity modulates|dobj|secretion agent|acl:relcl|modulates one|nmod|agent emerged|nmod|one emerged|nsubj|y y|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentrations|compound|start_entity determinant|nmod|concentrations identified|nmod|determinant identified|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 response|nmod|start_entity attenuated|nsubj|response attenuated|advcl|preserved preserved|nsubjpass|release release|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 cluster|amod|start_entity cluster|amod|uptake uptake|nmod|ph. ph.|nmod|loss loss|nmod|mutations mutations|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 2.000000 0 treated|nmod|start_entity cultures|acl|treated increases|nmod|cultures increases|nsubj|exposure exposure|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 antagonist|compound|start_entity reduced|nsubj|antagonist reduced|dobj|effect effect|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 stimulation|nmod|start_entity stimulation|nmod|phosphorylation phosphorylation|amod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 -rsb-|compound|start_entity diabetes_mellitus|nmod|-rsb- diminution|nmod|diabetes_mellitus diminution|nmod|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 suppressed|nsubj|start_entity suppressed|nmod|immunization immunization|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 derived|dobj|start_entity performed|parataxis|derived performed|xcomp|evaluate evaluate|dobj|role role|nmod|synthase synthase|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 5.000000 0 1.000000 0 7.000000 0 experiments|compound|start_entity isoforms|nmod|experiments isoforms|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 release|compound|start_entity activates|dobj|release activates|nsubj|dihydropyridine_receptor dihydropyridine_receptor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 form|amod|start_entity expressing|dobj|form mice|acl|expressing showed|nsubj|mice showed|advcl|controls controls|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nsubj|implications implications|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 group|compound|start_entity lower|nmod|group lower|nsubj|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity decrease|nmod|levels inhibited|dobj|decrease inhibited|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 chemotherapy|nmod|start_entity treated|nmod|chemotherapy monitored|advcl|treated monitored|dobj|transcripts transcripts|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 2.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 responses|nmod|start_entity blocked|nsubjpass|responses blocked|nmod|capsazepine capsazepine|compound|end_entity 4.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 supplement|compound|start_entity restored|nmod|supplement restored|xcomp|suggesting suggesting|ccomp|inhibit inhibit|nmod|inhibition inhibition|nmod|production production|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 information|amod|start_entity information|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 start_entity|ref|which undergo|nsubj|which undergo|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|compound|start_entity sensitivity|nmod|metabolism state|nmod|sensitivity reflects|dobj|state reflects|nsubj|over-all over-all|acl|indicating indicating|dobj|sensitivity sensitivity|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 appears|nsubj|start_entity appears|xcomp|unable unable|dep|normalize normalize|dobj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 12.000000 0 2.000000 0 0.000000 0 6.000000 0 0.000000 0 depends|nmod|start_entity depends|nsubj|release release|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 clustering|nmod|start_entity expression|appos|clustering imply|nsubj|expression clustering|acl:relcl|imply clustering|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 management|nmod|start_entity leaves|nsubj|management leaves|advcl|effective effective|advcl|reducing reducing|dobj|cholesterol cholesterol|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 production|compound|start_entity preceded|nsubj|production preceded|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 flux|compound|start_entity regulated|nmod|flux regulated|nsubjpass|expression expression|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 implicated|nmod|start_entity implicated|nmod|control control|nmod|function function|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 organic_anion_transporting_polypeptide|appos|start_entity organic_anion_transporting_polypeptide|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity release|dep|effect release|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 gut|compound|start_entity found|nmod|gut found|xcomp|suggesting suggesting|ccomp|secreted secreted|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 correction|nmod|start_entity correction|nmod|resistance resistance|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 irinotecan|amod|start_entity increases|nsubj|irinotecan increases|acl:relcl|found found|nsubj|cm/s cm/s|nmod|cm/s cm/s|acl:relcl|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 competition|amod|start_entity endogenous|dobj|competition endogenous|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 switching|nmod|start_entity associated|nsubjpass|switching associated|nmod|increases increases|nmod|levels levels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 phosphorylation|compound|start_entity increased|nsubjpass|phosphorylation increased|nmod|adipose adipose|nmod|rats rats|acl|infused infused|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 prevented|nsubj|start_entity prevented|dobj|expression expression|amod|cytokine-induced cytokine-induced|dep|production production|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 milieu|compound|start_entity varies|nmod|milieu varies|nsubj|effect effect|nmod:poss|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 tone|compound|start_entity required|nsubjpass|tone required|nmod|maintenance maintenance|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 8.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 self-association|nmod|start_entity prevention|nmod|self-association prevention|dep|effect effect|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 stimulation|compound|start_entity insulin|nmod|stimulation presence|nmod|insulin lower|nmod|presence lower|nmod|treatment treatment|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 synthase|amod|start_entity synthase|appos|cyclooxygenase_2 cyclooxygenase_2|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 production|nmod|start_entity tested|nmod|production tested|advcl|identify identify|dobj|mechanism mechanism|nmod|action action|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 doses|nmod|start_entity occupancy|appos|doses occupancy|compound|end_entity 2.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 utilisation|amod|start_entity response|appos|utilisation mediates|dobj|response mediates|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 supplementation|amod|start_entity supplementation|nmod|release release|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitor|amod|start_entity inhibited|nmod|inhibitor inhibited|nsubjpass|activation activation|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 containing|dobj|start_entity segment|acl|containing resulting|nmod|segment seen|advcl|resulting seen|nmod|segments segments|nmod:poss|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|advcl|decreased decreased|nsubj|activity activity|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 effect|nmod|start_entity due|nmod|effect due|nsubj|decrease decrease|nmod|gc gc|nmod|follicles follicles|acl:relcl|express express|dobj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 acts|nsubj|start_entity acts|advcl|stimulus stimulus|acl|used used|xcomp|suppress suppress|dobj|induction induction|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 juice|amod|start_entity inhibitors|nmod|juice inhibitors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 interaction|nmod|start_entity found|nsubjpass|interaction found|ccomp|found found|nmod|subjects subjects|nmod|levels levels|nmod|exposure exposure|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 -rsb-|nummod|start_entity -rsb-|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 13.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 depletion|compound|start_entity effects|nmod|depletion investigate|dobj|effects investigate|nmod|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 background|dep|start_entity background|acl|produced produced|nmod|action action|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 mmol|nmod|start_entity natriuresis|nmod|mmol caused|dobj|natriuresis caused|nmod|increase increase|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 mk-954|compound|start_entity losartan|appos|mk-954 inhibitors|nmod|losartan inhibitors|compound|end_entity 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 isomerase|amod|start_entity allozymes|amod|isomerase allozymes|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 using|dobj|start_entity using|nmod|activators activators|compound|end_entity 4.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptors|compound|start_entity expressed|nsubjpass|receptors expressed|nmod|end_entity 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 3.000000 0 1.000000 0 1.000000 0 intact|amod|start_entity end_entity|amod|intact 0.000000 0 0.000000 0 1.000000 0 0.000000 0 6.000000 0 62.000000 0 0.000000 0 0.000000 0 67.000000 0 0.000000 0 administration|amod|start_entity resulted|nsubj|administration resulted|nmod|decreases decreases|nmod|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 absorption|compound|start_entity mediated|nsubjpass|absorption mediated|advcl|provides provides|nsubj|glucose_transporter_2 glucose_transporter_2|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 15.000000 0 0.000000 0 1.000000 0 diet|compound|start_entity decreased|nmod|diet decreased|nsubjpass|expression expression|nmod|mrna mrna|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 response|compound|start_entity potentiated|dobj|response potentiated|nmod|neurons neurons|compound|end_entity 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 conversion|nmod|start_entity enzyme|nmod|conversion cyclooxygenase-2|appos|enzyme cyclooxygenase-2|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 acts|nsubj|start_entity acts|nmod|cyclooxygenase-1 cyclooxygenase-1|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 3.000000 0 4.000000 0 0.000000 0 1.000000 0 0.000000 0 receptor|compound|start_entity acts|nmod|receptor acts|xcomp|regulate regulate|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 concentrations|compound|start_entity suppressible|nmod|concentrations suppressible|nsubj|release release|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 18.000000 0 0.000000 0 start_entity|dobj|repair repair|nmod|ii ii|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|nmod|start_entity effects|nmod|treatment quantification|dep|effects quantification|nmod|protein protein|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 +|compound|start_entity +|appos|+ low|nsubj|+ low|dobj|concentrations concentrations|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 -rsb-|appos|start_entity -rsb-|nummod|-lsb- -lsb-|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 nefa|dep|start_entity nefa|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 release|nmod|start_entity enhance|dobj|release enhance|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 5.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 liver|nmod|start_entity galactosylated|nsubj|liver galactosylated|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 combination|amod|start_entity trastuzumab|nmod|combination demonstrated|nsubj|trastuzumab demonstrated|nmod|breast_cancer breast_cancer|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 status|compound|start_entity critical|nsubj|status test|ccomp|critical performed|advcl|test performed|dobj|study study|acl:relcl|characterized characterized|nmod|concentrations concentrations|nmod|vitamin_a vitamin_a|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 secretion|nmod|start_entity induced|dobj|secretion induced|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 effects|nmod|start_entity effects|dep|indolinyl-n indolinyl-n|appos|n-dimethyl_carbamate n-dimethyl_carbamate|nmod|isoenzymes isoenzymes|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 kinase|amod|start_entity fgf_receptor-1|amod|kinase fgf_receptor-1|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity associated|nmod|effect associated|nmod|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 release|nmod|start_entity feasible|nsubj|release feasible|ccomp|conveyor conveyor|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 dismutase|amod|start_entity manganese|amod|dismutase manganese|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 development|nmod|start_entity provide|nmod|development provide|dobj|overview overview|nmod|+ +|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 type|appos|start_entity prostaglandin|nmod|type administration|nmod|prostaglandin effect|nmod|administration investigated|dobj|effect investigated|nmod|distribution distribution|nmod|gene gene|dep|mrna mrna|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 residues|amod|start_entity residues|dep|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 production|amod|start_entity reflecting|dobj|production tumor_necrosis_factor-alpha|dep|reflecting tumor_necrosis_factor-alpha|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 molecule|nmod|start_entity contained|nsubjpass|molecule contained|nmod|structure structure|nmod|form form|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 3.000000 0 0.000000 0 analogues|nmod|start_entity series|nmod|analogues prepared|nsubjpass|series prepared|nmod|effects effects|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 ability|nmod|start_entity explain|dobj|ability differences|acl:relcl|explain similar|nmod|differences assembly|acl:relcl|similar forms|dobj|assembly forms|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|amod|start_entity influences|dobj|metabolism c.|parataxis|influences c.|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 phosphorylation|amod|start_entity stimulated|dobj|phosphorylation administration|acl|stimulated 14|appos|administration receptor-binding|nsubj|14 receptor-binding|dobj|protein protein|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 species|compound|start_entity generation|nmod|species generation|acl:relcl|promote promote|dobj|activation activation|amod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 level|compound|start_entity characterized|nsubjpass|level characterized|nmod|resistance resistance|nmod|level level|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 levels|compound|start_entity control|nmod|levels mortality|nmod|control effect|nmod|mortality concerning|dobj|effect concerning|nmod|infusion infusion|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 therapy|amod|start_entity course|nmod|therapy low|nmod|course low|nsubj|levels levels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 phytochemicals|amod|start_entity potential|nmod|phytochemicals comparing|dobj|potential describe|advcl|comparing describe|dobj|properties properties|nmod|activators activators|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 c-type_natriuretic_peptide|nmod|start_entity micrograms|amod|c-type_natriuretic_peptide micrograms|acl|stimulated stimulated|advcl|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 produced|nmod|start_entity those|acl|produced comparable|nmod|those elicit|xcomp|comparable showing|ccomp|elicit showing|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity range|nmod|levels less|nmod|range less|nsubj|concentration concentration|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 regulation|amod|start_entity affect|dobj|regulation stem|xcomp|affect stem|nsubj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 production|compound|start_entity purification|nmod|production purification|nmod|peroxidase peroxidase|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 reduce|nsubj|start_entity reduce|dobj|production production|nmod|tumor_necrosis_factor-alpha tumor_necrosis_factor-alpha|appos|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 8.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 blocking|nmod|start_entity blocking|dobj|cxcr4 cxcr4|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 0.000000 0 comparison|amod|start_entity investigated|nmod|comparison investigated|nsubjpass|influence influence|nmod|p-glycoprotein p-glycoprotein|appos|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 9.000000 0 0.000000 0 0.000000 0 0.000000 0 m.|amod|start_entity stimulated|nsubj|m. stimulated|dobj|release release|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 levels|compound|start_entity assess|nmod|levels assess|dobj|effects effects|nmod|hyperglycemia hyperglycemia|nmod|absence absence|nmod|changes changes|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 level|nmod|start_entity increases|nmod|level increases|nsubj|resistance resistance|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 dose|nmod|start_entity ingestion|nmod|dose intervals|nmod|ingestion measured|nmod|intervals measured|nsubjpass|response response|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 abrogated|nmod|start_entity effects|acl:relcl|abrogated growth|appos|effects caused|nmod|growth caused|nmod|estrogen_receptor estrogen_receptor|appos|end_entity 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 reported|nmod|start_entity features|acl|reported overlap|nmod|features mutations|amod|overlap system|nmod|mutations system|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 start_entity|acl:relcl|modifies modifies|dobj|activity activity|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 3.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 responses|compound|start_entity comparable|nsubj|responses comparable|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 influx|compound|start_entity thought|nsubjpass|influx studied|advcl|thought studied|nmod|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 species|compound|start_entity involving|dobj|species mechanism|acl|involving regulated|nmod|mechanism regulated|nsubjpass|induction induction|nmod|mrna mrna|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 sensitivity|compound|start_entity determinant|nmod|sensitivity determinant|nmod|phosphorylation phosphorylation|nmod|end_entity 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 i|nummod|start_entity increased|dobj|i showed|parataxis|increased showed|dobj|minimal minimal|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 caused|nmod|start_entity modulate|ccomp|caused end_entity|acl:relcl|modulate 1.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 determined|nmod|start_entity formed|advcl|determined formed|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 cyclic_amp|appos|start_entity excretion|nmod|cyclic_amp infusing|nmod|excretion infusing|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 channel|compound|start_entity designated|nmod|channel designated|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 no|appos|start_entity regulates|dobj|no suggest|ccomp|regulates known|parataxis|suggest known|nmod|signalling signalling|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 levels|amod|start_entity correlated|nmod|levels correlated|nsubjpass|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 release|compound|start_entity inhibition|nmod|release acts|nmod|inhibition administration|acl:relcl|acts administration|nmod|gh-releasing_hormone gh-releasing_hormone|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 level|compound|start_entity elevated|dobj|level elevated|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 geranylgeranylacetone|appos|start_entity effects|nmod|geranylgeranylacetone study|dobj|effects study|nmod|expression expression|nmod|heat_shock_protein70 heat_shock_protein70|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 vary|nmod|start_entity vary|nmod|end_entity 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 agonists|amod|start_entity treatment|nmod|agonists improvement|nmod|treatment failure|nmod|improvement reduced|nsubj|failure reduced|parataxis|circulating circulating|dobj|levels levels|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 antiandrogenicity|nmod|start_entity related|nsubjpass|antiandrogenicity related|nmod|antagonists antagonists|amod|end_entity 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 determine|xcomp|start_entity determine|nmod|addition addition|nmod|inhibitor inhibitor|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 7.000000 0 8.000000 0 16.000000 0 1.000000 0 5.000000 0 0.000000 0 metabolite|compound|start_entity measurements|nmod|metabolite inferred|nmod|measurements inferred|nsubjpass|inhibition inhibition|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 vitamin_d|nsubj|start_entity vitamin_d|nmod|interacts interacts|nmod|polymorphisms polymorphisms|nmod|region region|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 has|nsubj|start_entity has|dobj|disadvantage disadvantage|nmod|stimulation stimulation|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 mol/l|dobj|start_entity mol/l|csubj|responded responded|advcl|current current|acl|activated activated|nmod|atp atp|nmod|receptors receptors|nummod|end_entity 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 inhibited|nsubj|start_entity inhibited|nmod|concentration concentration|nmod|m m|acl:relcl|value value|acl|obtained obtained|nmod|inactivators inactivators|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nmod|positions positions|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 action|nmod|start_entity mediated|nsubjpass|action mediated|nmod|mu-opioid_receptor mu-opioid_receptor|appos|end_entity 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 methods|appos|start_entity methods|appos|sex_hormone_binding_protein sex_hormone_binding_protein|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|acl|stimulated stimulated|advcl|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitors|amod|start_entity inhibitors|amod|hepatotoxicity hepatotoxicity|nmod|use use|nmod|catechol-o-methly_transferase catechol-o-methly_transferase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 0.000000 0 enzyme|nmod|start_entity metabolism|amod|enzyme metabolism|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 3.000000 0 3.000000 0 0.000000 0 1.000000 0 0.000000 0 withdrawal|amod|start_entity using|nmod|withdrawal expression|acl|using expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 sensitivity|nmod|start_entity increased|dobj|sensitivity increased|nsubj|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 il-1_alpha-induced|dep|start_entity secretion|amod|il-1_alpha-induced inhibited|dobj|secretion inhibited|advcl|increased increased|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 dehydrogenase|amod|start_entity cholinesterase|appos|dehydrogenase cholinesterase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 action|nmod|start_entity mechanism|nmod|action regardless|nmod|mechanism consequence|advmod|regardless consequence|nmod|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 307|compound|start_entity phosphorylation|dep|307 proceeded|nmod|phosphorylation proceeded|nsubjpass|decrease decrease|nmod|protein protein|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 flare|compound|start_entity avoiding|dobj|flare terms|acl|avoiding possesses|nmod|terms possesses|dobj|advantages advantages|nmod|analogues analogues|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 12-o-tetradecanoylphorbol-13-acetate|appos|start_entity cells|nmod|12-o-tetradecanoylphorbol-13-acetate treatment|nmod|cells stimulates|nsubj|treatment stimulates|dobj|accumulation accumulation|nmod|rna rna|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 requires|dobj|start_entity requires|nsubj|end_entity 1.000000 0 0.000000 0 3.000000 0 2.000000 0 3.000000 0 18.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 everolimus|appos|start_entity compound|nsubj|everolimus compound|acl:relcl|inhibits inhibits|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 6.000000 0 0.000000 0 1.000000 0 0.000000 0 methoxyflavone|appos|start_entity effect|dep|methoxyflavone effect|nmod|inhibitor inhibitor|nmod|end_entity 0.000000 0 2.000000 0 0.000000 0 1.000000 0 2.000000 0 2.000000 0 13.000000 0 0.000000 0 1.000000 0 0.000000 0 acquisition|compound|start_entity involved|nmod|acquisition proteins|acl|involved coding|nmod|proteins mrnas|acl|coding located|nmod|mrnas proteins|acl|located proteins|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 channels|compound|start_entity inhibit|dobj|channels inhibit|nsubj|anandamide anandamide|appos|endocannabinoids endocannabinoids|acl:relcl|activate activate|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 start_entity|appos|inhibitor inhibitor|acl|targeting targeting|dobj|domain domain|nmod|vascular_endothelial_growth_factor_receptor_2 vascular_endothelial_growth_factor_receptor_2|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 deposits|compound|start_entity have|nsubj|deposits evident|advcl|have evident|nmod|carriers carriers|nmod|mutations mutations|nmod:poss|gene gene|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 signal.hif-1a|compound|start_entity signal.hif-1a|acl:relcl|adjusts adjusts|dobj|transcription transcription|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 leukotriene_b4|appos|start_entity effects|nmod|leukotriene_b4 majority|nmod|effects mediates|dobj|majority mediates|nsubj|leukotriene_b4_receptor_1 leukotriene_b4_receptor_1|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 analogs|compound|start_entity studies|nmod|analogs carrying|dobj|studies developed|advcl|carrying developed|dobj|blockers blockers|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|compound|start_entity dependent|nsubj|uptake dependent|nmod|release release|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 receptor|compound|start_entity receptor|appos|epidermal_growth_factor_receptor epidermal_growth_factor_receptor|acl:relcl|epidermal_growth_factor_receptor epidermal_growth_factor_receptor|nsubj|2 2|appos|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 aldosterone-induced|nmod|start_entity demonstrated|ccomp|aldosterone-induced demonstrated|nsubj|quantification quantification|nmod|distribution distribution|compound|end_entity 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibited|nsubj|start_entity had|advcl|inhibited had|dobj|effect effect|nmod|levels levels|nmod|mrna mrna|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 4.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 restriction|nmod|start_entity required|nmod|restriction required|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 adenosine_diphosphate|appos|start_entity addition|nmod|adenosine_diphosphate employ|nmod|addition employ|xcomp|improve improve|advcl|mitigating mitigating|dobj|contribution contribution|nmod|pathway pathway|compound|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 metabolism|compound|start_entity alterations|nmod|metabolism alterations|nmod|fluoxetine fluoxetine|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nmod|brain brain|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 transporters|nsubj|start_entity transporters|ccomp|found found|nsubjpass|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 2.000000 0 inhibited|nmod|start_entity k|dep|inhibited k|nsubj|cotransporter_type_1 cotransporter_type_1|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 _|amod|start_entity end_entity|amod|_ 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 shunting|dobj|start_entity plays|advcl|shunting plays|nsubj|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 17.000000 0 5.000000 0 0.000000 0 contrast|nmod|start_entity less|nmod|contrast less|nsubj|content content|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 3.000000 0 0.000000 0 1.000000 0 0.000000 0 insensitivity|compound|start_entity signs|nmod|insensitivity associated|nmod|signs cause|ccomp|associated cause|nsubj|mutations mutations|nmod|gene gene|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 14.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 receptors|compound|start_entity pharmacology|nmod|receptors hippocampal|nsubj|pharmacology hippocampal|dobj|pyramidal_neurones pyramidal_neurones|nummod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 has|nsubj|start_entity has|dobj|effects effects|nmod|vivo vivo|appos|e.g. e.g.|acl:relcl|depletes depletes|dobj|neurons neurons|nmod|tachykinins tachykinins|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 3.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibited|nmod|start_entity inhibited|dobj|effects effects|nmod|bolus bolus|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 levels|nmod|start_entity decreased|dobj|levels decreased|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 efficacious|nsubj|start_entity efficacious|nmod|itcs itcs|nmod|induction induction|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 agent|nsubj|start_entity agent|acl:relcl|blocks blocks|nmod|basic_fibroblast_growth_factor basic_fibroblast_growth_factor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 translocase|amod|start_entity interacts|nmod|translocase described|advcl|interacts described|nsubjpass|1 1|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 action|nmod|start_entity inhibited|advcl|action inhibited|dobj|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 8.000000 0 18.000000 0 2.000000 0 2.000000 0 1.000000 0 preincubation|amod|start_entity prevented|nsubj|preincubation prevented|advcl|causing causing|dobj|number number|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 addition|nmod|start_entity induces|nsubj|addition induces|dobj|alpha-helix alpha-helix|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 curve|nmod|start_entity area|nmod|curve increased|nsubj|area increased|nmod|saline saline|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 doses|nmod|start_entity dose|acl:relcl|doses ranged|nmod|dose ranged|nsubj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|nmod|start_entity effective|nsubj|levels effective|advcl|regulating regulating|nmod|areas areas|acl:relcl|activated activated|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 responses|compound|start_entity enhance|dobj|responses enhance|nsubj|end_entity 0.000000 0 0.000000 0 10.000000 0 2.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 penetration|nmod|start_entity associated|nmod|penetration associated|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 2.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nmod|nad nad|acl:relcl|crucial crucial|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibited|nsubj|start_entity inhibited|dobj|kinase kinase|amod|end_entity 0.000000 0 3.000000 0 0.000000 0 2.000000 0 11.000000 0 9.000000 0 20.000000 0 0.000000 0 1.000000 0 0.000000 0 molecule|nmod|start_entity predicts|dobj|molecule predicts|advcl|striking striking|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 messenger|dep|start_entity responsible|nsubj|messenger responsible|nmod|downregulation downregulation|nmod|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 little|xcomp|start_entity suggests|ccomp|little warranted|advcl|suggests warranted|nsubjpass|genotyping genotyping|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 values|compound|start_entity end_entity|nsubj|values 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 suppressed|nmod|start_entity levels|parataxis|suppressed levels|nmod|mrna mrna|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 status|compound|start_entity worsened|nmod|status worsened|parataxis|remained remained|nsubj|function function|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 fractions|nmod|start_entity sex_hormone-binding_globulin|appos|fractions sex_hormone-binding_globulin|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 targets|compound|start_entity described|dobj|targets described|nmod|family family|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity effects|nmod|generation generation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 extrusion|compound|start_entity altering|dobj|extrusion altering|advcl|using using|dobj|dioa dioa|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 3.000000 0 0.000000 0 protein|compound|start_entity protein|acl:relcl|inhibits inhibits|dobj|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity found|dobj|effects found|nmod|activation activation|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthesis|nmod|start_entity step|nmod|synthesis ligase|appos|step ligase|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitors|compound|start_entity explain|nmod|inhibitors mutations|acl|explain mutations|nmod|domain domain|nmod|end_entity 0.000000 0 0.000000 0 7.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 n-oxidation|amod|start_entity evaluated|nsubjpass|n-oxidation evaluated|advcl|impact impact|nmod|polymorphisms polymorphisms|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 kinases|amod|start_entity e.g.|appos|kinases receptors|dep|e.g. stimulation|nmod|receptors cancer-types|nmod|stimulation activated|nmod|cancer-types becomes|xcomp|activated kinase|acl:relcl|becomes kinase|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 indomethacin|nmod|start_entity indomethacin|appos|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity led|nsubj|treatment led|dobj|reductions reductions|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 efflux|amod|start_entity restricting|dobj|efflux restricting|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 produces|nsubj|start_entity produces|advcl|acting acting|nmod|agonist agonist|nmod|end_entity 4.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 -rsb-|compound|start_entity decreasing|dobj|-rsb- reduced|csubj|decreasing reduced|dobj|transient transient|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 spontaneous|compound|start_entity spontaneous|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 efficacy|nmod|start_entity depends|nsubj|efficacy depends|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 regulation|compound|start_entity dependence|nmod|regulation depended|nmod|dependence depended|nmod|expression expression|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 oncogenes|amod|start_entity oncogenes|dep|yes yes|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 dismutase|amod|start_entity activity|nmod|dismutase increase|nmod|activity was|nsubj|increase was|nmod|changes changes|nmod|activity activity|nmod|peroxidase peroxidase|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 effective|nmod|start_entity effective|nsubj|etoricoxib etoricoxib|appos|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 concentrations|amod|start_entity reduced|nsubjpass|concentrations elevated|advcl|reduced remained|ccomp|elevated remained|nsubj|concentrations concentrations|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 variability|nmod|start_entity took|nmod|variability took|advcl|exploiting exploiting|dobj|polymorphism polymorphism|dep|3 3|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 2.000000 0 methoxsalen|dep|start_entity inhibitor|nsubj|methoxsalen inhibitor|nmod|cytochrome_p450_2a6 cytochrome_p450_2a6|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 receptor|amod|start_entity linking|dobj|receptor linking|nmod|synthase synthase|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 stimulation|nmod|start_entity induced|nmod|stimulation activity|acl|induced activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 induced|nmod|start_entity antagonized|dep|induced antagonized|parataxis|sensitive sensitive|nsubj|receptor receptor|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 taking|dobj|start_entity evaluated|advcl|taking evaluated|nsubjpass|polymorphisms polymorphisms|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 excitation|nmod|start_entity mediated|nsubjpass|excitation mediated|nmod|receptors receptors|nummod|end_entity 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 imaging|compound|start_entity using|dobj|imaging observed|xcomp|using observed|nsubjpass|variations variations|acl|affected affected|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 mobilization|compound|start_entity resulted|nmod|mobilization resulted|ccomp|supporting supporting|dobj|role role|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 11.000000 0 0.000000 0 4.000000 0 12.000000 0 1.000000 0 elevated|nsubj|start_entity elevated|ccomp|documenting documenting|dobj|spectrum spectrum|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 levels|nmod|start_entity genotype|nmod|levels genotype|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treated|nmod|start_entity guinea-pigs|acl|treated activity|nmod|guinea-pigs activity|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 mediating|nmod|start_entity indicates|advcl|mediating indicates|dobj|role role|nmod|end_entity 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 sites|compound|start_entity identified|nsubj|sites identified|ccomp|conserved conserved|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibited|nmod|start_entity inhibited|nsubjpass|cells cells|acl|lacking lacking|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 start_entity|compound|_ _|nummod|end_entity 0.000000 0 2.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|compound|start_entity genes|nmod|metabolism one|nmod|genes end_entity|appos|one 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 method|nmod|start_entity end_entity|nsubj|method 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 analogue|compound|start_entity applied|nmod|analogue approach|acl|applied approach|dep|increasing increasing|dobj|absorption absorption|nmod|inhibitors inhibitors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 2.000000 0 5.000000 0 0.000000 0 1.000000 0 0.000000 0 current|compound|start_entity component|nmod|current element|nmod|component element|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 studies|nmod|start_entity aims|advcl|studies aims|xcomp|determine determine|ccomp|has has|nsubj|rivastigmine rivastigmine|appos|inhibitor inhibitor|nmod|acetylcholinesterase acetylcholinesterase|appos|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 promotes|nsubj|start_entity promotes|dobj|survival survival|nmod|osteoclasts osteoclasts|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 output|compound|start_entity decreased|nsubj|output revealed|ccomp|decreased revealed|ccomp|suppressed suppressed|nsubjpass|level level|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 18.000000 0 0.000000 0 levels|compound|start_entity raised|dobj|levels raised|advcl|receiving receiving|dobj|mixture mixture|nmod|glucose glucose|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 inhibitors|amod|start_entity use|nmod|inhibitors use|nmod|epidermal_growth_factor_receptor epidermal_growth_factor_receptor|appos|end_entity 0.000000 0 0.000000 0 7.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 therapy|amod|start_entity efficacy|nmod|therapy predictor|nmod|efficacy end_entity|acl:relcl|predictor 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 occurs|nmod|start_entity occurs|nsubj|level level|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 18.000000 0 0.000000 0 contrary|appos|start_entity suppress|nmod|contrary suppress|nsubj|antagonist antagonist|amod|end_entity 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 form|nsubj|start_entity mice|acl:relcl|form active|nmod|mice active|nsubj|enzyme enzyme|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 function|nmod|start_entity function|nsubj|rate rate|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 activity|nmod|start_entity potentiated|dobj|activity potentiated|nmod|assay assay|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 prevented|nmod|start_entity effect|acl|prevented weeks|appos|effect increased|nmod|weeks increased|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 presence|nmod|start_entity dependent|nmod|presence dependent|nsubj|activity activity|acl|observed observed|nmod|absence absence|nmod|end_entity 1.000000 0 0.000000 0 5.000000 0 1.000000 0 0.000000 0 9.000000 0 0.000000 0 5.000000 0 3.000000 0 0.000000 0 rhoa|compound|start_entity serves|nsubj|rhoa suggesting|ccomp|serves influence|advcl|suggesting influence|nsubj|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 level|compound|start_entity opposite|nsubj|level lower|advcl|opposite lower|nsubj|level level|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 concentration|amod|start_entity association|nmod|concentration replicated|dobj|association replicated|nmod|ratio ratio|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 resistance|amod|start_entity exhibited|dobj|resistance exhibited|nsubj|patients patients|nmod|mutations mutations|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 2.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 absorption|compound|start_entity absorption|acl|driven driven|nmod|suppression suppression|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 11.000000 0 0.000000 0 4.000000 0 12.000000 0 1.000000 0 interferon-alpha|compound|start_entity end_entity|compound|interferon-alpha 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 production|compound|start_entity production|nmod|bone bone|acl:relcl|indicates indicates|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 n-methyl_d-aspartate|appos|start_entity induced|nmod|n-methyl_d-aspartate seizures|acl|induced quercetin|nmod|seizures heat_shock_proteins_70_kda|acl|quercetin heat_shock_proteins_70_kda|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 species|compound|start_entity production|nmod|species play|nsubj|production play|dobj|role role|nmod|sensitivity sensitivity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 antagonist|compound|start_entity clearance|nmod|antagonist returned|nmod|clearance surges|dep|returned surges|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 study|nmod|start_entity study|nmod|aa3 aa3|amod|cytochrome cytochrome|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 repair|nmod|start_entity role|nmod|repair plays|dobj|role plays|nsubj|1 1|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 kinase|compound|start_entity growth_arrest-specific_protein|nsubj|kinase growth_arrest-specific_protein|dep|induces induces|dobj|activation activation|nmod|end_entity 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 receptor|compound|start_entity gpr17|nmod|receptor experiments|nmod|gpr17 reports|appos|experiments consistent|nmod|reports suggested|nsubj|consistent suggested|ccomp|acts acts|nsubj|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 biosynthesis|amod|start_entity step|nmod|biosynthesis carries|dobj|step membrane|acl:relcl|carries delivers|nmod|membrane delivers|nsubj|steroidogenic_acute_regulatory_protein steroidogenic_acute_regulatory_protein|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 transport|compound|start_entity promotes|dobj|transport apolipoprotein|acl:relcl|promotes apolipoprotein|nsubj|factor factor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 relationships|nmod|start_entity remained|nsubj|relationships remained|xcomp|significant significant|nmod|tissue tissue|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 13.000000 0 0.000000 0 level|compound|start_entity drop|nmod|level provoked|dobj|drop provoked|nsubj|exposure exposure|nmod|cells cells|amod|monocytic monocytic|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 synthesis|compound|start_entity expression|appos|synthesis expression|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 modulation|amod|start_entity implicate|nmod|modulation implicate|dobj|ras ras|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 hypomethylated|dep|start_entity hypomethylated|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 8.000000 0 adiponectin|appos|start_entity adiponectin|appos|acids acids|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 38.000000 0 0.000000 0 3.000000 0 63.000000 0 0.000000 0 release|amod|start_entity measure|nmod|release measure|nmod|doses doses|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 targets|nsubj|start_entity targets|dobj|isoform isoform|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 10.000000 0 0.000000 0 1.000000 0 0.000000 0 compare|nmod|start_entity compare|nmod|blockade blockade|nmod|angiotensin_ii angiotensin_ii|appos|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentrations|compound|start_entity related|nmod|concentrations related|xcomp|implying implying|ccomp|account account|nsubj|exposure exposure|acl|associated associated|nmod|polymorphisms polymorphisms|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 tertiles|nmod|start_entity dividing|nmod|tertiles confined|advcl|dividing confined|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 reduction|nmod|start_entity donor|nmod|reduction utilize|nmod|donor utilize|advmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|acl|indicating indicating|ccomp|mediates mediates|nsubj|activation activation|nmod|receptors receptors|nummod|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 uptake|amod|start_entity inhibition|amod|uptake inhibition|amod|potency potency|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 k|nmod|start_entity exhibiting|nmod|k expressing|advcl|exhibiting expressing|dobj|protein protein|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 absence|nmod|start_entity induce|nmod|absence induce|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|appos|amino_acids amino_acids|acl|known known|nmod|inhibitors inhibitors|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity elevated|nsubj|treatment elevated|nmod|hdpcs hdpcs|acl:relcl|reversed reversed|nmod|silencing silencing|compound|end_entity 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitors|acl|start_entity inhibited|nmod|inhibitors inhibited|nmod|transfection transfection|nmod|sirna sirna|nmod|phox phox|amod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 production|amod|start_entity assessed|nsubjpass|production assessed|nmod|gonadotrophin gonadotrophin|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 elements|amod|start_entity interacts|nmod|elements core|acl:relcl|interacts containing|dobj|core bipartite|xcomp|containing bipartite|nsubj|domain domain|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 transporters|amod|start_entity colocalizes|nmod|transporters opioid|ccomp|colocalizes established|ccomp|opioid established|nsubj|microscopy microscopy|acl|using using|dobj|gold-silver gold-silver|acl|labeling labeling|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 levels|compound|start_entity modulated|nmod|levels modulated|nsubjpass|release release|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 presence|nmod|start_entity treated|nmod|presence treated|advcl|assess assess|advcl|moderating moderating|dobj|effects effects|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 sequence|amod|start_entity carrying|dobj|sequence carrying|nmod|qkraa qkraa|dep|positions positions|nmod|chain chain|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptors|compound|start_entity role|nmod|receptors assess|dobj|role kainate|xcomp|assess kainate|nsubj|agonist agonist|nmod|receptors receptors|acl:relcl|include include|nmod|conjunction conjunction|nmod|mice mice|acl|deficient deficient|nmod|end_entity 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transport|nmod|start_entity diminished|dobj|transport diminished|nsubj|presence presence|nmod|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 used|nsubjpass|start_entity used|parataxis|behaves behaves|nmod|blocker blocker|nmod|acetylcholinesterase acetylcholinesterase|appos|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 supplied|nmod|start_entity supplied|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 serotonin|appos|start_entity implicated|nsubjpass|serotonin implicated|nmod|processes processes|nmod|satiation satiation|dep|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolites|compound|start_entity contrast|nmod|metabolites me-dtc|nmod|contrast inhibitor|nsubj|me-dtc inhibitor|nmod|aldehyde_dehydrogenase aldehyde_dehydrogenase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 5.000000 0 0.000000 0 1.000000 0 0.000000 0 recognizes|nsubj|start_entity receptor|acl:relcl|recognizes receptor|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 exposure|amod|start_entity associated|nmod|exposure sequela|acl|associated one|nmod|sequela express|ccomp|one express|dobj|amount amount|nmod|end_entity 4.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|ccomp|treated treated|nmod|end_entity 0.000000 0 7.000000 0 2.000000 0 0.000000 0 1.000000 0 8.000000 0 4.000000 0 0.000000 0 4.000000 0 0.000000 0 pyk2|amod|start_entity acts|nsubj|pyk2 acts|nmod|tyr9 tyr9|acl:relcl|permits permits|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 concentrations|nmod|start_entity profiles|nmod|concentrations ph-dependent|nmod|profiles ph-dependent|nsubj|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pathway|amod|start_entity involved|nmod|pathway involved|nsubjpass|end_entity 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 subunit|amod|start_entity encode|dobj|subunit mutations|acl:relcl|encode mutations|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 relation|nmod|start_entity remained|nsubj|relation correlated|parataxis|remained correlated|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 4.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 activation|compound|start_entity promotes|nmod|activation promotes|dobj|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 had|nsubj|start_entity convert|ccomp|had convert|nmod|cni cni|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 subunit|compound|start_entity configuration|nmod|subunit coding|nmod|configuration coding|dobj|1 1|acl:relcl|sequenced sequenced|dobj|region region|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 concentrations|compound|start_entity suppressed|nmod|concentrations suppressed|nsubjpass|synthesis synthesis|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 18.000000 0 0.000000 0 pancreocyte|nmod|start_entity response|nmod|pancreocyte leading|nmod|response discharges|acl|leading discharges|appos|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 transport|amod|start_entity effect|nmod|transport has|dobj|effect has|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 hydrolysis|compound|start_entity inhibits|dobj|hydrolysis inhibits|advcl|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effects|nmod|start_entity investigated|dobj|effects investigated|advcl|follow follow|dobj|parathyroid_hormone parathyroid_hormone|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 addition|compound|start_entity recapitulated|nmod|addition observation|acl|recapitulated formation|appos|observation reduced|dobj|formation reduced|nsubj|exposure exposure|nmod|amd3100 amd3100|compound|end_entity 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 8.000000 0 0.000000 0 1.000000 0 0.000000 0 enzymes-alcohol_dehydrogenase|compound|start_entity enzymes-alcohol_dehydrogenase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 2.000000 0 islets|acl|start_entity release|nmod|islets release|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 response|compound|start_entity reductions|nmod|response lowered|nmod|reductions lowered|dobj|responses responses|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 inhibitors|dep|start_entity inhibitors|amod|/ /|dep|months months|nmod|treatment treatment|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 pharmacokinetics|nmod|start_entity genotypes|nmod|pharmacokinetics genotypes|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 ch2cl2|appos|start_entity ch2cl2|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 fraction|nmod|start_entity removing|dobj|fraction responsible|advcl|removing sufficient|advcl|responsible sufficient|nsubj|difference difference|nmod|levels levels|amod|functional functional|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 availability|nmod|start_entity availability|nmod|treatment treatment|nmod|patients patients|nmod|non-small_cell_lung_cancer non-small_cell_lung_cancer|acl|selected selected|nmod|presence presence|nmod|rearrangement rearrangement|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 9.000000 0 0.000000 0 2.000000 0 0.000000 0 inhibit|advmod|start_entity inhibit|dobj|action action|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 meals|nmod|start_entity response|nmod|meals response|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 down-regulated|nmod|start_entity demonstrate|parataxis|down-regulated demonstrate|ccomp|down-modulate down-modulate|dobj|shedding shedding|nmod|receptors receptors|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 induced|nsubj|start_entity induced|advcl|measured measured|nmod|assay assay|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 technique|compound|start_entity measured|nmod|technique measured|nsubjpass|sensitivity sensitivity|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 3.000000 0 0.000000 0 84.000000 0 0.000000 0 9.000000 0 174.000000 0 0.000000 0 treated|advcl|start_entity difference|acl|treated difference|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 administration|nmod|start_entity protect|nsubj|administration observe|advcl|protect infused|advcl|observe infused|nsubjpass|pepstatin pepstatin|appos|inhibitor inhibitor|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 structure|amod|start_entity containing|dobj|structure regulator|acl|containing encodes|dobj|regulator encodes|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 dehydrogenase|amod|start_entity residue|nmod|dehydrogenase substitution|nmod|residue changes|nsubj|substitution changes|nmod|that that|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 transport|compound|start_entity vesicles|nsubj|transport vesicles|xcomp|containing containing|dobj|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 17.000000 0 5.000000 0 0.000000 0 resistance|compound|start_entity correlated|nmod|resistance cells|acl|correlated expression|nmod|cells expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treated|nmod|start_entity diagnosis|acl:relcl|treated prior|nmod|diagnosis describe|advmod|prior describe|dobj|occurrence occurrence|nmod|increase increase|nmod|level level|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 6.000000 0 0.000000 0 1.000000 0 0.000000 0 7-n-demethylation|nmod|start_entity 8-hydroxylation|nmod|7-n-demethylation amitriptyline|nmod|8-hydroxylation influence|nmod|amitriptyline weaker|nsubj|influence weaker|xcomp|suggesting suggesting|dobj|spectrum spectrum|acl|involving involving|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 homeostasis|compound|start_entity disorders|nmod|homeostasis role|nmod|disorders demonstrated|nsubjpass|role demonstrated|nmod|discovery discovery|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 injection|compound|start_entity observed|nmod|injection observed|advcl|increased increased|nsubjpass|expression expression|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 applied|dobj|start_entity applied|nsubj|receptors receptors|acl|containing containing|ccomp|mediate mediate|nsubj|subunits subunits|amod|end_entity 0.000000 0 0.000000 0 13.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentration|nmod|start_entity suppress|nsubj|concentration suppress|dobj|biosynthesis biosynthesis|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|acl|induced induced|dobj|transcription transcription|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 consumption|compound|start_entity levels|nmod|consumption investigating|nmod|levels investigating|dobj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 retrieval|amod|start_entity role|nmod|retrieval has|dobj|role has|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 inhibits|nsubj|start_entity inhibits|dobj|trans-signal trans-signal|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 reduced|parataxis|start_entity reduced|advcl|added added|nsubjpass|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 trigger|nsubj|start_entity trigger|nmod|normalisation normalisation|nmod|effects effects|acl|fasting fasting|advcl|restoring restoring|dobj|capacity capacity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 transport|compound|start_entity site|nsubj|transport site|nmod|resistance resistance|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 superfamily|amod|start_entity belongs|nmod|superfamily receptors|acl:relcl|belongs member|nmod|receptors member|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 controls|compound|start_entity controls|nmod|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 take|dobj|start_entity suppressing|advcl|take improve|advcl|suppressing improve|nsubj|restoration restoration|nmod|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 concentrations|compound|start_entity serum|dobj|concentrations increased|xcomp|serum increased|nmod|restoration restoration|nmod|relationship relationship|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 18.000000 0 0.000000 0 statuses|compound|start_entity secretions|nmod|statuses secretions|nsubj|correlation correlation|nmod|effect effect|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 production|amod|start_entity reduction|nmod|production due|nsubj|reduction due|nmod|protein protein|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 had|nmod|start_entity had|nsubj|inhibitor inhibitor|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 fasting|dobj|start_entity assessed|advcl|fasting assessed|nsubjpass|levels levels|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 inhibits|nsubj|start_entity kinase|ccomp|inhibits kinase|nsubj|tyrosine tyrosine|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 release|compound|start_entity alter|dobj|release alter|nsubj|mutations mutations|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 administration|amod|start_entity caused|nsubj|administration caused|nmod|immunoreactivity immunoreactivity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 metabolism|amod|start_entity affect|dobj|metabolism affect|nsubj|inhibition inhibition|nmod|monoamine_oxidase_b monoamine_oxidase_b|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 absence|nmod|start_entity gtp-gamma-s|nmod|absence exposure|nmod|gtp-gamma-s reduced|nmod|exposure reduced|nsubjpass|content content|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 conversion|nmod|start_entity requiring|dobj|conversion pathway|acl|requiring end_entity|nmod|pathway 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 remethylation|nmod|start_entity catalyzes|dobj|remethylation catalyzes|advcl|contribute contribute|nsubj|stimulation stimulation|nmod|remethylation remethylation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 region|nmod|start_entity implicated|dobj|region implicated|nsubj|presence presence|nmod|similarities similarities|nmod|region region|nmod|portions portions|nmod|proteins proteins|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 due|nmod|start_entity due|nmod|lack lack|nmod|expression expression|nmod|contract contract|amod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 consumers|compound|start_entity those|nmod|consumers higher|nmod|those higher|nsubj|values values|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 toxicity|appos|start_entity toxicity|nmod|mainly mainly|nmod|gene gene|appos|end_entity 4.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 insulin|nmod|start_entity clearance|nmod|insulin 0.66|nsubj|clearance 0.66|acl|+ +|dobj|min min|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 17.000000 0 0.000000 0 start_entity|nsubj|activities activities|nmod|epidermal_growth-factor_receptor epidermal_growth-factor_receptor|appos|end_entity 0.000000 0 0.000000 0 7.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 activity|amod|start_entity targeting|dobj|activity pharmacotherapy|xcomp|targeting pharmacotherapy|nsubj|up-regulation up-regulation|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 terms|nmod|start_entity capacity|nmod|terms functional|dep|capacity mobilization|amod|functional associated|nmod|mobilization associated|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 receptor|amod|start_entity changes|nmod|receptor genetically|nmod|changes loci|amod|genetically loci|appos|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 3.000000 0 caffeine|nmod|start_entity induces|dep|caffeine induces|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 metabolites|nmod|start_entity n-hydroxylation|nsubj|metabolites n-hydroxylation|dep|formed formed|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 hydroxylase|amod|start_entity levels|nmod|hydroxylase exhibit|nmod|levels exhibit|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1st|appos|start_entity potency|nmod|1st compared|nsubjpass|potency compared|nmod|cells cells|acl:relcl|express express|dobj|end_entity 0.000000 0 1.000000 0 0.000000 0 1.000000 0 7.000000 0 3.000000 0 13.000000 0 0.000000 0 1.000000 0 0.000000 0 infused|nmod|start_entity rats|acl:relcl|infused end_entity|nmod|rats 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 flux|compound|start_entity mediates|dobj|flux mediates|nsubj|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 26.000000 0 2.000000 0 1.000000 0 transport|compound|start_entity increase|nmod|transport accompanied|nsubjpass|increase accompanied|nmod|increase increase|nmod|content content|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 16.000000 0 2.000000 0 0.000000 0 inhibitor|amod|start_entity epidermal_growth_factor_receptor|dep|inhibitor benefit|nmod|epidermal_growth_factor_receptor acquire|nmod|benefit acquire|nsubj|lung_adenocarcinoma lung_adenocarcinoma|amod|end_entity 0.000000 0 0.000000 0 7.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 using|nsubj|start_entity resulted|parataxis|using resulted|nsubj|inhibitor inhibitor|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 1.000000 0 3.000000 0 1.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 activating|parataxis|start_entity activating|dobj|mutations mutations|nmod|pathway pathway|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 production|compound|start_entity deficient|nmod|production elevated|parataxis|deficient elevated|nmod|hearts hearts|nmod|mice mice|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 availability|nmod|start_entity role|nmod|availability plays|dobj|role plays|nsubj|steroidogenic_acute_regulatory_protein steroidogenic_acute_regulatory_protein|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 adenosine_monophosphate|appos|start_entity adenosine_monophosphate|nmod|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 deprivation|compound|start_entity reduced|nsubj|deprivation reduced|advcl|suggesting suggesting|ccomp|contain contain|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 release|amod|start_entity modulation|nmod|release involved|nmod|modulation involved|nmod|activation activation|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 memory_deficits|amod|start_entity inhibition|nmod|memory_deficits inhibition|nsubj|catechol-o-methyltransferase catechol-o-methyltransferase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 0.000000 0 protein|nmod|start_entity decrease|nmod|protein correlated|nsubj|decrease correlated|nmod|suppression suppression|nmod|synthesis synthesis|nmod|protein protein|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 deprivation|compound|start_entity treated|nmod|deprivation patients|acl|treated develop|nsubj|patients develop|advcl|increasing increasing|dobj|levels levels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 measure|nmod|start_entity measure|dobj|affinity affinity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 mhc|compound|start_entity mhc|acl|induction induction|nmod|end_entity 1.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 10.000000 0 0.000000 0 1.000000 0 0.000000 0 reducing|dobj|start_entity signaling|advcl|reducing dampens|xcomp|signaling dampens|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 10.000000 0 3.000000 0 0.000000 0 receptor|amod|start_entity interrelated|nsubj|receptor led|ccomp|interrelated led|nsubj|ability ability|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 receptor|compound|start_entity release|nmod|receptor release|nsubj|ca ca|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 affected|nmod|start_entity affected|xcomp|signaling signaling|dobj|acts acts|nmod|receptor receptor|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 indicated|nmod|start_entity indicated|advcl|substrates substrates|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 investigate|nsubj|start_entity investigate|dobj|influence influence|acl|mediated mediated|nmod|release release|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 study|nmod|start_entity conducted|dobj|study conducted|nmod|nsclc nsclc|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 1.000000 0 7.000000 0 3.000000 0 13.000000 0 0.000000 0 1.000000 0 0.000000 0 facilitate|nsubj|start_entity facilitate|dep|signaling signaling|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|dobj|inhibitor inhibitor|acl|induced induced|advcl|ecog ecog|nmod|therapy therapy|nmod|patients patients|amod|end_entity 0.000000 0 0.000000 0 7.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 levels|amod|start_entity examined|nsubjpass|levels examined|nmod|injection injection|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptor|amod|start_entity harboring|dobj|receptor harboring|dep|mutation mutation|acl|known known|advcl|develops develops|nsubj|pv pv|dep|mouse mouse|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 triglycerides|appos|start_entity fasting|nsubj|triglycerides log|ccomp|fasting higher|advcl|log higher|nsubj|values values|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 achieves|nsubj|start_entity achieves|nmod|inhibition inhibition|compound|end_entity 0.000000 0 2.000000 0 0.000000 0 0.000000 0 14.000000 0 16.000000 0 35.000000 0 2.000000 0 10.000000 0 0.000000 0 enhanced|nsubj|start_entity enhanced|nmod|promoter promoter|appos|promoter promoter|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 n-methyl-d-aspartate|appos|start_entity independent|nmod|n-methyl-d-aspartate hippocampus|acl:relcl|independent end_entity|nmod|hippocampus 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 regulation|compound|start_entity role|nmod|regulation role|nmod|enhancer enhancer|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 repair|amod|start_entity involved|nmod|repair involved|nsubj|characterization characterization|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 blocked|nsubj|start_entity blocked|nmod|activity activity|nmod|mapk mapk|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|acl|altered altered|dobj|effects effects|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 potentiates|nsubj|start_entity potentiates|dobj|regulation regulation|amod|functional functional|advmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentrations|nmod|start_entity regulates|dobj|concentrations regulates|nsubj|protein protein|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 activity|amod|start_entity inhibition|nmod|activity molecules|nmod|inhibition available|nsubj|molecules available|advcl|target target|nsubj|end_entity 0.000000 0 0.000000 0 7.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 receptor|amod|start_entity c-met|appos|receptor acting|nmod|c-met functions|acl|acting regulates|dobj|functions regulates|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 lowering|dobj|start_entity had|advcl|lowering had|nsubj|1,9-dideoxyforskolin 1,9-dideoxyforskolin|acl:relcl|binds binds|dobj|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 23.000000 0 2.000000 0 1.000000 0 capacity|compound|start_entity calculated|nsubjpass|capacity calculated|dep|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 effects|nmod|start_entity compared|dobj|effects compared|advcl|elucidate elucidate|nmod|action action|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 18.000000 0 0.000000 0 blockade|compound|start_entity treatment|nmod|blockade reviewed|nsubjpass|treatment based|advcl|reviewed based|nsubj|design design|dep|pertinent pertinent|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 excess|amod|start_entity cells|nmod|excess protect|dobj|cells protect|nsubj|substrates substrates|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 suppressed|compound|start_entity endogenous|nsubj|suppressed endogenous|ccomp|signaling signaling|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 added|nsubjpass|start_entity added|nmod|list list|nmod|stimuli stimuli|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 phosphorylation|compound|start_entity lead|nmod|phosphorylation lead|nsubj|treatment treatment|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|acl|inhibition inhibition|advcl|interfering interfering|nmod|synthesis synthesis|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity amplified|nsubj|treatment amplified|parataxis|decreased decreased|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 abts|nmod|start_entity necessary|nmod|abts necessary|nsubj|regulation regulation|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 abolished|nmod|start_entity abolished|nsubjpass|increase increase|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 called|dobj|start_entity called|nsubj|inhibitor inhibitor|nmod|activity activity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 4.000000 0 0.000000 0 1.000000 0 0.000000 0 synthesis|amod|start_entity rate-limiting|nmod|synthesis study|advcl|rate-limiting study|dobj|regulation regulation|nmod|induction induction|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nsubj|alterations alterations|nmod|end_entity 0.000000 0 1.000000 0 5.000000 0 0.000000 0 0.000000 0 6.000000 0 4.000000 0 23.000000 0 3.000000 0 2.000000 0 centrilobular|nmod|start_entity detection|nmod|centrilobular useful|nmod|detection useful|nsubj|measurement measurement|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effectiveness|nmod|start_entity re-evaluated|dobj|effectiveness used|parataxis|re-evaluated used|dobj|inhibitor inhibitor|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 7.000000 0 8.000000 0 16.000000 0 1.000000 0 5.000000 0 0.000000 0 induced|nmod|start_entity induced|nsubj|involvement involvement|nmod|histidine_isoleucine histidine_isoleucine|nmod|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 start_entity|acl:relcl|depletes depletes|advcl|blocking blocking|dobj|uptake uptake|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 removal|nmod|start_entity increased|nmod|removal increased|nsubj|ratio ratio|nmod|cells cells|acl|containing containing|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentrations|compound|start_entity had|nmod|concentrations had|dobj|levels levels|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 18.000000 0 0.000000 0 concentration|compound|start_entity reduce|nsubj|concentration reduce|dobj|concentrations concentrations|nmod|mice mice|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 aa|nsubj|start_entity aa|advcl|controlling controlling|advcl|modulating modulating|dobj|level level|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 galr2|amod|start_entity galr2|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 appearance|compound|start_entity measured|nmod|appearance meal|acl|measured meal|acl:relcl|administered administered|nsubjpass|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 metabolism|amod|start_entity determinants|nmod|metabolism determinants|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 using|dobj|start_entity evaluation|acl|using evaluation|nmod|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 conversion|nmod|start_entity catalyzes|dobj|conversion catalyzes|nsubj|dopamine_beta-hydroxylase dopamine_beta-hydroxylase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 14.000000 0 synthase|compound|start_entity proteins|appos|synthase induces|dobj|proteins induces|advcl|induces induces|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibits|nsubj|start_entity inhibits|dobj|endocytosis endocytosis|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 homeostasis|compound|start_entity homeostasis|nmod|mice mice|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 1.000000 0 13.000000 0 0.000000 0 inhibits|amod|start_entity restenosis|nsubj|inhibits restenosis|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 relative|amod|start_entity amounts|nmod|relative contain|dobj|amounts contain|nsubj|glands glands|acl|incubated incubated|nmod|presence presence|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 acts|amod|start_entity acts|nmod|isoforms isoforms|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 order|nmod|start_entity cefroxadine|nmod|order uptake|nmod|cefroxadine inhibited|dobj|uptake inhibited|nsubj|inhibitors inhibitors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 8.000000 0 0.000000 0 2.000000 0 0.000000 0 content|compound|start_entity influenced|nmod|content influenced|nsubjpass|binding binding|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 start_entity|dobj|locus locus|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 receptors|compound|start_entity subunit|nmod|receptors encoding|dobj|subunit balance|acl|encoding balance|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 areg|nmod|start_entity display|advcl|areg display|nsubj|cells cells|amod|deficient deficient|nmod|end_entity 4.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receiving|dobj|start_entity prescribed|xcomp|receiving study|acl:relcl|prescribed shown|nmod|study unknown|advcl|shown unknown|nsubj|interaction interaction|acl:relcl|inhibitors inhibitors|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 homeostasis|compound|start_entity regulates|dobj|homeostasis kinase|acl:relcl|regulates end_entity|appos|kinase 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 action|nmod|start_entity mode|nmod|action evaluate|dobj|mode used|advcl|evaluate used|dobj|rapamycin rapamycin|appos|inhibitor inhibitor|nmod|complex-1 complex-1|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 domains|compound|start_entity domains|nmod|subunit subunit|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|acl|located located|dobj|levels levels|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 receptor|compound|start_entity subunits|nsubj|receptor subunits|ccomp|resulting resulting|nsubj|end_entity 0.000000 0 0.000000 0 14.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 dehydrogenase|amod|start_entity adaptation|nmod|dehydrogenase end_entity|nsubj|adaptation 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 rise|nmod|start_entity increased|nsubjpass|rise increased|nmod|patients patients|nmod|hereditary_haemochromatosis hereditary_haemochromatosis|appos|+ +|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 ppi|nmod|start_entity generates|dobj|ppi ectonucleotidase|acl:relcl|generates enpp1|appos|ectonucleotidase expressing|dobj|enpp1 crossed|xcomp|expressing crossed|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 mechanism|dep|start_entity mechanism|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 hydrogen_peroxide|appos|start_entity link|nmod|hydrogen_peroxide suggested|nsubjpass|link suggested|xcomp|leading leading|ccomp|factor factor|acl|regulating regulating|dobj|expression expression|nmod|cells cells|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 reduced|nsubj|start_entity reduced|dobj|concentrations concentrations|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 7.000000 0 2.000000 0 0.000000 0 3.000000 0 0.000000 0 levels|nmod|start_entity end_entity|dep|levels 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 5.000000 0 2.000000 0 10.000000 0 caused|nsubj|start_entity raised|dep|caused raised|nsubj|octreotide octreotide|appos|analog analog|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity pharmacokinetics|nsubj|effect pharmacokinetics|nmod|mutations mutations|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 domain|dep|start_entity domain|nmod|cells cells|acl|showing showing|ccomp|restricted restricted|nsubjpass|inhibition inhibition|nmod|activities activities|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 accumulation|nmod|start_entity added|nsubj|accumulation added|ccomp|sensitive sensitive|nsubj|impact impact|nmod|extracts extracts|nmod|status status|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptor|compound|start_entity function|nsubj|receptor function|advcl|tweaks tweaks|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 measurement|nmod|start_entity fluo-3|dep|measurement loaded|advcl|fluo-3 loaded|advcl|study study|dobj|transients transients|acl|elicited elicited|advcl|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 phosphorylation|nmod|start_entity burst|nmod|phosphorylation observed|nsubjpass|burst observed|advcl|added added|nsubjpass|+ +|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 actions|nmod|start_entity number|nmod|actions mediated|nsubjpass|number demonstrated|ccomp|mediated directed|ccomp|demonstrated directed|nsubj|kinase kinase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pneumonitis|amod|start_entity patients|nmod|pneumonitis had|nsubj|patients had|dobj|increase increase|nmod|cells cells|nummod|+ +|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 entry|nmod|start_entity pathway|nmod|entry end_entity|nsubj|pathway 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 reabsorption|nmod|start_entity inhibit|dobj|reabsorption impairing|ccomp|inhibit believed|xcomp|impairing believed|xcomp|caused caused|nmod|levels levels|ref|which glycosylate|nsubj|which glycosylate|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 strips|compound|start_entity claim|nmod|strips users|nmod|claim accounted|nmod|users accounted|nmod|one-fourth one-fourth|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 enantiomers|amod|start_entity pharmacokinetics|nmod|enantiomers determine|nmod|pharmacokinetics determine|dobj|role role|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 injection|nmod|start_entity induced|nmod|injection appeared|advcl|induced appeared|nmod|pattern pattern|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 progressed|nmod|start_entity patients|acl:relcl|progressed patients|nmod|colorectal_cancer colorectal_cancer|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 addition|nmod|start_entity treated|nmod|addition treated|nmod|presence presence|nmod|naproxen naproxen|appos|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 agonist|amod|start_entity 2-br-alpha-ergocryptine|amod|agonist treatment|nmod|2-br-alpha-ergocryptine decreased|nsubj|treatment decreased|dobj|content content|nmod|mrna mrna|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 actions|compound|start_entity occur|nsubj|actions occur|nmod|increase increase|nmod|expression expression|nmod|isoform isoform|compound|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 metabolism|amod|start_entity assays|nmod|metabolism assays|nmod|probe probe|nmod|isoforms isoforms|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 production|compound|start_entity resulted|nmod|production resulted|nsubj|lowering lowering|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 exposure|compound|start_entity increase|nsubj|exposure increase|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 results|compound|start_entity consumption|nmod|results consumption|nmod|level level|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 inhibition|compound|start_entity inhibition|nummod|end_entity 0.000000 0 0.000000 0 11.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity lowers|dobj|levels lowers|nmod|secretion secretion|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 17.000000 0 0.000000 0 start_entity|appos|factor factor|acl|activated activated|nmod|cyclic_amp cyclic_amp|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 il-2-r|nmod|start_entity inhibited|nsubj|il-2-r inhibited|dobj|synthesis synthesis|nmod|mrna mrna|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 glucuronosyl|amod|start_entity transferase|nsubj|glucuronosyl transferase|dobj|1a1 1a1|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 start_entity|nsubj|knockdown knockdown|acl|resulted resulted|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pre-surgery|compound|start_entity /|dep|pre-surgery 0.6|nmod|/ /|dep|0.6 hyperglycaemia|dep|/ hyperglycaemia|nmod|concentrations concentrations|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 molecules|acl:relcl|start_entity receptor|nmod|molecules receptor|nsubj|aryl_hydrocarbon_receptor aryl_hydrocarbon_receptor|appos|end_entity 2.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 stimulates|nummod|start_entity crf|nsubj|stimulates crf|dobj|release release|acl:relcl|has has|dobj|interactions interactions|nmod|end_entity 1.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|acl:relcl|induce induce|dobj|enzyme enzyme|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 8.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 concentrations|amod|start_entity correlated|nsubj|concentrations correlated|nmod|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 enhance|nsubj|start_entity added|ccomp|enhance reduces|advcl|added reduces|nsubj|alpha-difluoromethylornithine alpha-difluoromethylornithine|appos|inhibitor inhibitor|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 release|compound|start_entity role|nmod|release recognized|nmod|role recognized|nsubjpass|channels channels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 hydrolysis|nmod|start_entity catalyzing|dobj|hydrolysis capable|advcl|catalyzing capable|nsubj|enzymes enzymes|appos|i i|appos|ec ec|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 caused|nsubj|start_entity caused|advcl|abrogated abrogated|nsubj|inhibitors inhibitors|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 8.000000 0 18.000000 0 2.000000 0 2.000000 0 1.000000 0 load|compound|start_entity given|advcl|load injections|acl|given injections|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 inhibitor|compound|start_entity inhibitor|acl|designed designed|xcomp|target target|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 therapy|compound|start_entity myocardial_infarction|nmod|therapy risk|nmod|myocardial_infarction reduction|nmod|risk magnitude|nmod|reduction related|nsubjpass|magnitude related|nmod|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 protects|nsubj|start_entity protects|dobj|microvessels microvessels|dep|role role|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 accumulation|nmod|start_entity increase|dobj|accumulation increase|advcl|inhibiting inhibiting|dobj|function function|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 associated|nmod|start_entity pathways|acl|associated assess|dobj|pathways assess|nsubj|analysis analysis|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 1.000000 0 7.000000 0 3.000000 0 13.000000 0 0.000000 0 1.000000 0 0.000000 0 inhibitors|nmod|start_entity treatments|nsubj|inhibitors tyrosine|ccomp|treatments tyrosine|nsubj|anaplastic_lymphoma_kinase anaplastic_lymphoma_kinase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 9.000000 0 0.000000 0 2.000000 0 0.000000 0 receptors|amod|start_entity that|nmod|receptors similar|nmod|that similar|nsubj|domains domains|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 starvation|compound|start_entity induced|nsubj|starvation induced|dobj|activation activation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 encodes|dobj|start_entity gene|acl:relcl|encodes gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 33.000000 0 5.000000 0 0.000000 0 skin|nmod|start_entity treatment|nmod|skin events|nmod|treatment one|nmod|events induction|nsubj|one induction|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibited|nmod|start_entity reduced|ccomp|inhibited reduced|dobj|association association|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 accumulation|compound|start_entity effects|nmod|accumulation investigated|dobj|effects investigated|nmod|treatment treatment|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 uptake|compound|start_entity not|nmod|uptake intact|dep|not intact|dobj|stimulation stimulation|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 receptor|compound|start_entity realized|nsubjpass|receptor realized|parataxis|considered considered|nmod|+ +|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 effect|nmod|start_entity effect|acl|bearing bearing|dobj|rats rats|appos|acnu-mg acnu-mg|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 gene|amod|start_entity gene|acl|combined combined|nmod|assessment assessment|nmod|activity activity|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 model|appos|start_entity propose|dobj|model propose|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity due|nsubj|effect due|nmod|stabilization stabilization|nmod|mrna mrna|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 production|amod|start_entity leading|nmod|production synthase|acl|leading synthase|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 5.000000 0 2.000000 0 10.000000 0 active|nmod|start_entity three-fold|xcomp|active compound|acl:relcl|three-fold inhibitors|dep|compound inhibitors|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 9.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolizes|dobj|start_entity phosphodiesterase_3|acl:relcl|metabolizes phosphodiesterase_3|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 include|xcomp|start_entity activation|acl:relcl|include activation|nmod|peroxisome_proliferator-activated_receptor-a peroxisome_proliferator-activated_receptor-a|appos|end_entity 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 degradation|nmod|start_entity most|nmod|degradation plays|advcl|most plays|nsubj|enzyme enzyme|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|compound|start_entity remained|nsubj|effects remained|advcl|carried carried|nmod|antagonist antagonist|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nmod|pathway pathway|nmod|estrogen_receptor estrogen_receptor|appos|end_entity 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 subunit|nmod|start_entity snp|nmod|subunit snp|dep|kinase kinase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 disrupts|amod|start_entity fear|nsubj|disrupts fear|xcomp|learning learning|nmod|effect effect|nmod|activation activation|compound|end_entity 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 stress|nmod|start_entity evaluated|advcl|stress evaluated|dobj|kinetics kinetics|nmod|phosphorylation phosphorylation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|amod|start_entity increased|nsubjpass|uptake increased|nmod|increases increases|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 injection|nmod|start_entity removed|nmod|injection removed|nsubjpass|% %|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 polymorphisms|amod|start_entity screened|dobj|polymorphisms screened|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 intoxicants|compound|start_entity concentrations|nmod|intoxicants concentrations|acl:relcl|present present|nmod|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 evoked|nmod|start_entity output|acl|evoked output|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 series|nmod|start_entity confers|nmod|series confers|nsubj|protein protein|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 arginine-8-vasopressin|appos|start_entity end_entity|appos|arginine-8-vasopressin 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effect|nmod|start_entity stimulating|nsubj|effect stimulating|dobj|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 currents|compound|start_entity reduction|nmod|currents mirrored|nsubj|reduction mirrored|dobj|effects effects|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 production|nmod|start_entity affects|dobj|production affects|nsubj|insulin-like_growth_factor_i insulin-like_growth_factor_i|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 upregulate|xcomp|start_entity upregulate|nsubj|inhibitors inhibitors|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 activity|nmod|start_entity activity|nmod|lymphoid_malignancies lymphoid_malignancies|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 20alpha-dihydroprogesterone|amod|start_entity conversion|nmod|20alpha-dihydroprogesterone catalyzes|dobj|conversion catalyzes|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 abolished|nsubj|start_entity abolished|dobj|induction induction|nmod|reductions reductions|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 provide|nsubj|start_entity inhibitors|ccomp|provide inhibitors|nsubj|receptor receptor|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 concentration|compound|start_entity /|nsubj|concentration /|dep|+ +|amod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 metabolism|amod|start_entity disturbance|nmod|metabolism indicate|dobj|disturbance indicate|advcl|catalyzes catalyzes|advcl|ensuring ensuring|dobj|availability availability|nmod|substrate substrate|nmod|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 cascade|amod|start_entity cascade|nmod|end_entity 1.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 potent|nmod|start_entity potent|advcl|inhibiting inhibiting|dobj|edema edema|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 conversion|nmod|start_entity enzymes|nmod|conversion enzymes|nsubj|cyclooxygenases cyclooxygenases|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 administration|amod|start_entity subjected|nsubjpass|administration obtained|advcl|subjected obtained|advcl|elucidate elucidate|advcl|exists exists|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 levels|compound|start_entity increases|dobj|levels increases|nmod|angiotensin_ii angiotensin_ii|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 start_entity|advcl|increase increase|dobj|levels levels|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 cells|amod|start_entity use|nmod|cells permitting|dobj|use contains|advcl|permitting contains|dobj|gene gene|acl|encoding encoding|dobj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 2.000000 0 3.000000 0 0.000000 0 2.000000 0 0.000000 0 response|compound|start_entity magnitude|nmod|response decrease|nmod|magnitude dependent|nsubj|decrease dependent|nmod|concentration concentration|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 alpha|amod|start_entity change|nmod|alpha was|nsubj|change end_entity|dep|was 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 loading|compound|start_entity develop|dobj|loading develop|nmod|saturation saturation|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 suggests|nmod|start_entity suggests|nsubj|elevation elevation|nmod|fl fl|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 regulated|nmod|start_entity diabetic_liver|acl:relcl|regulated end_entity|nmod|diabetic_liver 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 predicting|nmod|start_entity indicator|acl|predicting indicator|nsubj|level level|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 antagonised|dobj|start_entity antagonised|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|nmod|protein protein|amod|heme_oxygenase-1 heme_oxygenase-1|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 inaccurate|nsubj|start_entity inaccurate|advcl|high high|nsubj|concentrations concentrations|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 production|nmod|start_entity inhibition|nmod|production associated|nsubjpass|inhibition associated|nmod|down-regulation down-regulation|nmod|isoenzyme isoenzyme|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 induce|nsubj|start_entity induce|nmod|apolipoprotein_e-knockout apolipoprotein_e-knockout|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 increased|nsubj|start_entity decreased|advcl|increased decreased|nsubj|sensitivity sensitivity|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 induced|nmod|start_entity damage|acl|induced diminished|nmod|damage diminished|nsubjpass|phosphorylation phosphorylation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 activation|nmod|start_entity end_entity|nmod|activation 2.000000 0 0.000000 0 4.000000 0 2.000000 0 5.000000 0 10.000000 0 9.000000 0 2.000000 0 2.000000 0 0.000000 0 system|nmod|start_entity inhibition|nmod|system examine|nsubj|inhibition examine|dobj|interaction interaction|nmod|end_entity 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 1.000000 0 0.000000 0 il-6|compound|start_entity levels|nmod|il-6 tumor_necrosis_factor_a|compound|levels tumor_necrosis_factor_a|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 presence|nmod|start_entity culturing|nmod|presence investigated|advcl|culturing investigated|nsubjpass|dynamics dynamics|nmod|synthesis synthesis|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 channel|compound|start_entity terminus|nmod|channel binds|nmod|terminus binds|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 toxicity|amod|start_entity effects|nmod|toxicity effects|nmod|-rsb- -rsb-|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 enzymes|amod|start_entity enzymes|appos|tyrosine_hydroxylase tyrosine_hydroxylase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 reduced|nmod|start_entity reduced|advcl|did did|nsubj|replacements replacements|nmod|domains domains|nmod|end_entity 0.000000 0 2.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 restriction|compound|start_entity reduce|nsubj|restriction reduce|dobj|sensitivity sensitivity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 phosphorylated|nmod|start_entity identified|xcomp|phosphorylated protein|acl|identified end_entity|appos|protein 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 administration|compound|start_entity transgenic_mice|nsubj|administration accompanied|xcomp|transgenic_mice accompanied|xcomp|mimicking mimicking|dobj|decrease decrease|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 attracted|dep|start_entity attracted|nsubj|enzymes enzymes|nmod|thymidylate_synthase thymidylate_synthase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|amod|start_entity treatment|acl|suggesting suggesting|ccomp|mediated mediated|nmod|end_entity 4.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 -rsb-|amod|start_entity decreases|nmod|-rsb- accompanies|dobj|decreases fall|acl:relcl|accompanies compensate|nmod|fall mechanism|acl:relcl|compensate provides|dobj|mechanism provides|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 degrading|dobj|start_entity process|acl|degrading limiting|nmod|process rate|acl|limiting end_entity|appos|rate 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 benefit|nmod|start_entity symptom|dep|benefit symptom|appos|blocker blocker|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 improve|nsubj|start_entity improve|nmod|virtue virtue|nmod|suppression suppression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|compound|start_entity due|nsubj|effects due|nmod|blockade blockade|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 background|dep|start_entity increases|nsubj|background increases|dobj|expression expression|nmod|bone_morphogenetic_protein_2 bone_morphogenetic_protein_2|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 reduced|nsubj|start_entity reduced|dobj|production production|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 2.000000 0 4.000000 0 16.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 homoeostasis|compound|start_entity determining|nmod|homoeostasis determining|dobj|function function|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 increased|nsubj|start_entity increased|nmod|fibroblasts fibroblasts|acl:relcl|prevented prevented|nmod|br-4628 br-4628|appos|antagonist antagonist|compound|end_entity 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 attenuation|appos|start_entity attenuation|nmod|voluntary_ethanol_consumption voluntary_ethanol_consumption|nmod|inhibition inhibition|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 export|compound|start_entity likely|nsubj|export mediated|dep|likely mediated|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 2.000000 0 0.000000 0 conditions|compound|start_entity cells|nmod|conditions il-1beta|nmod|cells il-1beta|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 differences|nmod|start_entity determined|nmod|differences determined|nsubjpass|differences differences|nmod|secretion secretion|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 1.000000 0 0.000000 0 9.000000 0 0.000000 0 abrogated|nsubj|start_entity induced|advcl|abrogated induced|dobj|activation activation|nmod|extracellular_signal-regulated_kinase extracellular_signal-regulated_kinase|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 11.000000 0 0.000000 0 0.000000 0 0.000000 0 pyridine_hydrochloride|appos|start_entity rs|dep|pyridine_hydrochloride rs|dep|chloro-5-hydroxyphenylglycine chloro-5-hydroxyphenylglycine|appos|agonist agonist|amod|end_entity 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 relative|nmod|start_entity relative|nmod:npmod|affinity affinity|nummod|end_entity 0.000000 0 0.000000 0 12.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 receptor|compound|start_entity receptor|nmod|molecule molecule|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 guidelines|compound|start_entity offer|nsubj|guidelines offer|xcomp|goal goal|nsubj|cholesterol cholesterol|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 effect|nmod|start_entity examined|dobj|effect examined|nmod|neurotransmission neurotransmission|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 oxidase|compound|start_entity isoform|nmod|oxidase isoform|nsubj|end_entity 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 start_entity|advcl|upregulating upregulating|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 3.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 receptor|compound|start_entity subset|nsubj|receptor subset|advmod|tumors tumors|nmod:npmod|end_entity 0.000000 0 0.000000 0 7.000000 0 3.000000 0 0.000000 0 6.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 secretion|amod|start_entity reduce|dobj|secretion reduce|nsubj|% %|dep|ng/min ng/min|nmod|suppression suppression|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 levels|compound|start_entity activity|nmod|levels lie|nsubj|activity lie|nmod|pathway pathway|nmod|allele allele|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effect|nmod|start_entity study|dobj|effect study|nmod|regulation regulation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 compounds|amod|start_entity treated|nmod|compounds rats|acl|treated examined|nmod|rats examined|nsubjpass|morphology morphology|appos|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 agents|nummod|start_entity agents|dep|penbutolol penbutolol|appos|end_entity 1.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 regulation|compound|start_entity +|nsubj|regulation candidate|ccomp|+ suggest|ccomp|candidate suggest|advcl|intracellular intracellular|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 reduced|nmod|start_entity reduced|nsubj|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 effectiveness|nmod|start_entity surveyed|dobj|effectiveness surveyed|nmod|mutations mutations|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 varied|nmod|start_entity data|acl|varied data|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity decreased|nmod|treatment decreased|xcomp|suggesting suggesting|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 using|dobj|start_entity composed|advcl|using end_entity|acl|composed 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 production|compound|start_entity roflumilast|nmod|production effects|nmod|roflumilast mediated|nsubjpass|effects mediated|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 provide|nsubj|start_entity provide|nmod|nsclc nsclc|acl|having having|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 paralogues|amod|start_entity paralogues|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 efficacy|nmod|start_entity study|nmod|efficacy iii/iv|nsubj|study iii/iv|nmod|mutations mutations|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 5.000000 0 12.000000 0 1.000000 0 0.000000 0 0.000000 0 hydrolysis|compound|start_entity available|nmod|hydrolysis energy|amod|available required|nsubjpass|energy essential|advcl|required essential|nsubj|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 production|compound|start_entity effect|nmod|production due|nmod|effect prevent|xcomp|due prevent|nsubj|1400w 1400w|appos|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 change|amod|start_entity change|nmod|site site|appos|775 775|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 degradation|nmod|start_entity catalyzes|nmod|degradation catalyzes|nsubj|enzyme enzyme|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 formation|amod|start_entity catalyzes|dobj|formation catalyzes|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 imatinib_mesylate|nsubj|start_entity imatinib_mesylate|xcomp|inhibiting inhibiting|dobj|kinase kinase|compound|end_entity 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 3.000000 0 fall|nmod|start_entity accompanied|nmod|fall decrease|acl:relcl|accompanied decrease|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 phosphorylation|amod|start_entity phosphorylation|appos|tub tub|acl|associated associated|nmod|domains domains|nmod|lck lck|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity mice|nmod|treatment elevated|nmod|mice elevated|nsubj|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effects|compound|start_entity attributed|nsubjpass|effects attributed|nmod|depletion depletion|acl:relcl|interrupted interrupted|dobj|activation activation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 treatment|amod|start_entity inhibited|nsubj|treatment inhibited|dobj|increase increase|nmod|mrna mrna|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 alters|nmod|start_entity factor|acl:relcl|alters factor|nsubj|aryl_hydrocarbon_receptor aryl_hydrocarbon_receptor|appos|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 studies|amod|start_entity used|nmod|studies cells|acl|used treatment|nmod|cells resulted|nsubj|treatment resulted|nmod|independent independent|nmod|expression expression|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 2.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 regulators|nmod|start_entity act|nmod|regulators act|nsubj|parathyroid_hormone parathyroid_hormone|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 18.000000 0 0.000000 0 peroxisome_proliferator_activated_receptor|amod|start_entity peroxisome_proliferator_activated_receptor|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treated|nmod|start_entity rats|acl|treated autoreceptors|nmod|rats autoreceptors|nsubj|desensitization desensitization|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 n-methyl_d-aspartate|appos|start_entity expression|nmod|n-methyl_d-aspartate evaluated|nmod|expression level|acl:relcl|evaluated level|appos|nr1 nr1|dep|end_entity 0.000000 0 0.000000 0 12.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 fingers|compound|start_entity clusters|nmod|fingers contain|dobj|clusters contain|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pretreatment|nmod|start_entity caused|nsubj|pretreatment caused|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 4.000000 0 1.000000 0 1.000000 0 1.000000 0 0.000000 0 represent|nmod|start_entity leukemias|acl:relcl|represent leukemias|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity growth_hormone-releasing_hormone|nmod|treatment depletion|nmod|growth_hormone-releasing_hormone reveals|nsubj|depletion reveals|nmod|secretion secretion|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 effects|nmod|start_entity resulting|nmod|effects elicited|advcl|resulting elicited|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 homeostasis|compound|start_entity regulation|nmod|homeostasis role|nmod|regulation factor|nmod|role factor|nsubj|hypoxia-inducible_factor-1alpha hypoxia-inducible_factor-1alpha|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity causing|dobj|levels serious_disorder|acl|causing serious_disorder|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 inhibitor|appos|start_entity receptor|dep|inhibitor receptor|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 12-o-tetradecanoyl-phorbol_13-acetate|appos|start_entity cultured|advcl|12-o-tetradecanoyl-phorbol_13-acetate cultured|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|amod|docetaxel increased|nsubj|docetaxel increased|advcl|influencing influencing|dobj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 isoflurane|compound|start_entity administration|nmod|isoflurane altered|nmod|administration altered|nsubjpass|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 protein|amod|start_entity genes|nmod|protein existence|nmod|genes expected|nsubjpass|existence searched|advcl|expected searched|nmod|homologues homologues|nmod|protein protein|acl|encoded encoded|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 storage|compound|start_entity protein|nmod|storage protein|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 stimulation|amod|start_entity weaker|nmod|stimulation strongest|amod|weaker suggest|parataxis|strongest suggest|ccomp|hormone-dependent hormone-dependent|nsubj|expression expression|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 conversion|nummod|start_entity found|nmod|conversion found|dobj|downregulation downregulation|nmod|pathway pathway|amod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|nmod|start_entity levels|nmod|activation activation|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 stimulation|compound|start_entity seen|nmod|stimulation seen|nsubjpass|increase increase|nmod|mrna mrna|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 modulate|dobj|start_entity catechol-o-methyltransferase|acl:relcl|modulate catechol-o-methyltransferase|appos|end_entity 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 day|amod|start_entity associated|nsubjpass|day associated|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 taking|dobj|start_entity women|acl|taking had|nsubj|women had|dobj|levels levels|acl|taking taking|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 utilizes|dobj|start_entity utilizes|csubj|bound bound|xcomp|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 induce|nsubj|start_entity induce|dobj|down-regulation down-regulation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 defect|amod|start_entity correction|nmod|defect give|iobj|correction give|nsubj|clones clones|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 kinase|amod|start_entity inactivation|nmod|kinase constant|nmod|inactivation rate|amod|constant estimated|nsubjpass|rate estimated|advcl|subtracting subtracting|nmod|samples samples|acl|replenished replenished|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 test|compound|start_entity showed|nsubj|test showed|dobj|increase increase|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 17.000000 0 0.000000 0 shown|nmod|start_entity shown|dobj|inhibitor inhibitor|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 1.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic_acid|appos|start_entity increase|nmod|alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic_acid triggers|dobj|increase triggers|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 phosphorylated|amod|start_entity kinase|amod|phosphorylated dephosphorylation|nmod|kinase coincided|nmod|dephosphorylation recruitment|acl:relcl|coincided elicited|dobj|recruitment elicited|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 toxicity|amod|start_entity mediates|nmod|toxicity mediates|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 neuromedin_b|nmod|start_entity role|nmod|neuromedin_b end_entity|nsubj|role 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 molecule|compound|start_entity energy|nmod|molecule kcal/mol|nsubj|energy kcal/mol|parataxis|indicates indicates|ccomp|exhibits exhibits|dobj|affinity affinity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 start_entity|nmod|intestine intestine|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 15.000000 0 0.000000 0 1.000000 0 induced|nmod|start_entity expression|acl|induced inhibited|dobj|expression inhibited|nsubj|oligonucleotides oligonucleotides|compound|end_entity 1.000000 0 0.000000 0 3.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 coapplication|nmod|start_entity coapplication|appos|inhibitors inhibitors|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 0.000000 0 residues|compound|start_entity phosphorylation|nmod|residues monitored|nsubjpass|phosphorylation monitored|xcomp|suggesting suggesting|dobj|order order|nmod|phosphorylation phosphorylation|nmod|tyrosines tyrosines|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 active|amod|start_entity gene|amod|active gene|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 4.000000 0 presence|nmod|start_entity accumulates|nmod|presence accumulates|nsubj|protein protein|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 administration|amod|start_entity findings|nmod|administration consistent|nmod|findings activity|amod|consistent activity|nummod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 syk|compound|start_entity syk|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 effect|amod|start_entity agonist|dep|effect agonist|amod|end_entity 6.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 homeostasis|amod|start_entity rely|nsubj|homeostasis rely|nmod|proteins proteins|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 agonists|nmod|start_entity 7-azaindoles|nmod|agonists receptor|amod|7-azaindoles receptor|appos|end_entity 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 3.000000 0 coordination|nmod|start_entity due|nmod|coordination due|nmod|cluster cluster|nmod|residues residues|nmod|ectodomain ectodomain|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 limits|dobj|start_entity end_entity|acl:relcl|limits 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 abrogated|nmod|start_entity inhibitors|ccomp|abrogated inhibitors|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 sequence|amod|start_entity sequence|nmod|sh1 sh1|nmod|chain chain|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 17-allylamino-17-demethoxygeldanamycin|dep|start_entity derivatives|amod|17-allylamino-17-demethoxygeldanamycin promising|nsubj|derivatives promising|dobj|drugs drugs|acl:relcl|inhibit inhibit|ccomp|function function|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity reverse|dobj|effect reverse|nsubj|hydroxyflutamide hydroxyflutamide|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 crizotinib|appos|start_entity inhibitor|nsubj|crizotinib inhibitor|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 suppressing|nmod|start_entity studied|advcl|suppressing studied|dep|help help|nmod|infusion infusion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 8.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 replete|nmod:npmod|start_entity patients|amod|replete anaemia|nmod|patients correct|dobj|anaemia correct|nsubj|therapy therapy|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 6.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 kinase|compound|start_entity functioning|nmod|kinase acts|advcl|functioning acts|xcomp|target target|dobj|signal_transducer_and_activator_of_transcription_3 signal_transducer_and_activator_of_transcription_3|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 replacement|compound|start_entity heart|nmod|replacement increased|nmod|heart increased|nsubjpass|levels levels|compound|end_entity 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 peptides|dep|start_entity family|nmod|peptides agonists|nmod|family cgrp|nsubj|agonists cgrp|nmod|ability ability|acl|activate activate|dobj|receptors receptors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 levels|amod|start_entity decreased|nsubj|levels decreased|nmod|decrease decrease|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 inhibition|compound|start_entity inhibition|nmod|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 site|compound|start_entity site|acl|located located|nmod|/ /|nmod|promoter promoter|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 administration|nmod|start_entity h|nmod|administration vivo|appos|h antagonism|nmod|vivo demonstrated|dobj|antagonism demonstrated|nsubj|measurement measurement|nmod|internalization internalization|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 changes|compound|start_entity observed|nsubjpass|changes observed|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metallopeptidase|compound|start_entity neutral_endopeptidase|appos|metallopeptidase neutral_endopeptidase|acl:relcl|shares shares|dobj|structure structure|nmod|angiotensin_converting_enzyme angiotensin_converting_enzyme|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 dismutase|amod|start_entity protein|amod|dismutase protein|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 function|amod|start_entity modulating|dobj|function augment|advcl|modulating suggests|ccomp|augment suggests|nsubj|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 factor|amod|start_entity functions|nmod|factor domain|nmod|functions domain|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 transporter|compound|start_entity expressed|dobj|transporter ubiquitously|acl|expressed has|advcl|ubiquitously has|nsubj|transporter transporter|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 production|amod|start_entity stimulated|dobj|production crf|acl|stimulated inhibited|dobj|crf antagonist|ccomp|inhibited antagonist|nsubj|receptor receptor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 prevented|advcl|start_entity prevented|dobj|reduction reduction|nmod|affinity affinity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 induced|nsubj|start_entity induced|nsubj|injection injection|nmod|antagonist antagonist|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 induced|nmod|start_entity phosphorylation|acl|induced inhibited|dobj|phosphorylation inhibitors|acl:relcl|inhibited had|nsubj|inhibitors had|nmod|effect effect|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pathway|nmod|start_entity inhibition|nmod|pathway blocked|nsubj|inhibition blocked|dobj|activation activation|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 1.000000 0 2.000000 0 4.000000 0 10.000000 0 0.000000 0 0.000000 0 0.000000 0 dose|compound|start_entity variants|nmod|dose variants|nsubj|association association|nmod|reductase reductase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 selective|nsubj|start_entity selective|nmod|inhibitor inhibitor|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 induced|nmod|start_entity accumulation|acl|induced accumulation|compound|end_entity 2.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 10.000000 0 0.000000 0 3.000000 0 1.000000 0 0.000000 0 systems|nmod|start_entity express|dobj|systems express|parataxis|identified identified|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 16.000000 0 1.000000 0 1.000000 0 agonists|compound|start_entity stimulation|nmod|agonists prior|nmod|stimulation wsc|advmod|prior treatment|nmod|wsc blocked|nsubj|treatment blocked|dobj|secretion secretion|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 effects|nmod|start_entity investigate|dobj|effects chromatography|xcomp|investigate using|xcomp|chromatography separated|xcomp|using separated|advcl|hb hb|nsubj|fractions fractions|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 level|amod|start_entity increased|nsubj|level was|advcl|increased was|nsubj|decline decline|nmod|level level|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 12.000000 0 2.000000 0 0.000000 0 6.000000 0 0.000000 0 treatment|compound|start_entity detected|nmod|treatment detected|nsubjpass|increase increase|nmod|immunoreactivity immunoreactivity|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 intersect|nmod|start_entity intersect|nmod|signaling signaling|appos|expression expression|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 11.000000 0 0.000000 0 4.000000 0 12.000000 0 1.000000 0 sensitivity|nmod|start_entity differ|nmod|sensitivity channels|acl:relcl|differ populations|nmod|channels equipped|nmod|populations proposed|ccomp|equipped proposed|advcl|reflects reflects|dobj|stimulation stimulation|nmod|entry entry|amod|end_entity 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 analog|compound|start_entity using|dobj|analog investigated|xcomp|using investigated|nsubjpass|site site|nmod|cocaine cocaine|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 exposure|nmod|start_entity mrna|nmod|exposure mrna|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|dep|start_entity 6|nmod|treatment elevated|nmod|6 elevated|nsubj|levels levels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 antagonist|amod|start_entity theophylline|appos|antagonist counteract|nsubj|theophylline counteract|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 face|amod|start_entity face|dep|assessment assessment|nmod|resistance resistance|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 results|compound|start_entity pulses|nmod|results exposure|nmod|pulses challenge|nsubj|exposure challenge|nmod|result result|nmod|desensitization desensitization|compound|end_entity 2.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 production|compound|start_entity control|nmod|production control|nsubj|glucose-6-phosphate_dehydrogenase glucose-6-phosphate_dehydrogenase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 translocates|amod|start_entity translocates|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 beta-oxidation|amod|start_entity enzymes|nmod|beta-oxidation encoding|dobj|enzymes genes|acl|encoding degree|nmod|genes reduced|dobj|degree feeding|acl:relcl|reduced caused|nsubj|feeding caused|nmod|ligand ligand|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 activates|nsubj|start_entity activates|dobj|phosphorylation phosphorylation|nmod|proteins proteins|nmod|kinase kinase|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.47|nmod|start_entity 0.47|nsubj|potency potency|nmod|action action|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 transport|compound|start_entity changes|nmod|transport accompanied|nsubjpass|changes determine|ccomp|accompanied determine|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 production|compound|start_entity shown|nmod|production responsiveness|acl|shown responsiveness|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 results|compound|start_entity nursing|nmod|results adjustable|advcl|nursing scale|acl:relcl|adjustable administered|nmod|scale administered|nsubjpass|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 release|amod|start_entity increase|nmod|release was|nsubj|increase was|advcl|injected injected|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibits|nsubj|start_entity inhibits|dobj|proliferation proliferation|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 3.000000 0 3.000000 0 0.000000 0 1.000000 0 0.000000 0 hesperidin|appos|start_entity liver|nmod|hesperidin mechanism|nmod|liver mechanism|nmod|activities activities|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 bioavailability|amod|start_entity role|nmod|bioavailability plays|dobj|role considered|advcl|plays considered|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 uptake|compound|start_entity uptake|nmod|activation activation|nmod|pathway pathway|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 both|amod|start_entity activate|nsubj|both activate|dobj|mineralocorticoid_receptor mineralocorticoid_receptor|appos|end_entity 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 antagonists|amod|start_entity effects|nmod|antagonists effects|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|appos|concentration concentration|acl:relcl|halted halted|nsubjpass|activation activation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 inhibition|nmod|start_entity promotes|nsubj|inhibition promotes|dobj|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthesis|amod|start_entity required|nmod|synthesis enzyme|acl|required end_entity|appos|enzyme 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 accumulation|compound|start_entity determined|nmod|accumulation determined|dobj|dependency dependency|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 intraperitoneally|amod|start_entity had|nsubj|intraperitoneally observed|parataxis|had observed|nsubjpass|patterns patterns|nmod|response response|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 infusion|compound|start_entity showed|nsubj|infusion restored|advcl|showed restored|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 18.000000 0 0.000000 0 capecitabine|compound|start_entity capecitabine|appos|regimens regimens|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 promotes|nsubj|start_entity promotes|dobj|growth growth|nmod|cancers cancers|nmod|m3_muscarinic_receptor m3_muscarinic_receptor|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 factor|amod|start_entity camp|dep|factor activated|nmod|camp proteins|acl|activated end_entity|dep|proteins 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 forms|nmod|start_entity forms|ccomp|protects protects|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity reduced|dobj|levels inhibition|acl:relcl|reduced inhibition|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 releaser|nsubj|start_entity releaser|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transporter|amod|start_entity encoding|dobj|transporter pho84|acl|encoding promoter|nmod|pho84 analysis|nmod|promoter revealed|nsubj|analysis revealed|ccomp|caused caused|nsubjpass|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 1.000000 0 0.000000 0 gnrh-a|dep|start_entity end_entity|dep|gnrh-a 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthesis|amod|start_entity stimulated|dobj|synthesis stimulated|advcl|stimulated stimulated|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 elevations|nmod|start_entity patients|nmod|elevations had|nsubj|patients had|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 1.000000 0 0.000000 0 cadmium|nmod|start_entity substitution|nmod|cadmium due|nmod|substitution suggesting|ccomp|due removed|xcomp|suggesting removed|nsubjpass|inhibition inhibition|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 prednisolone|amod|start_entity efficacy|nmod|prednisolone demonstrated|nsubjpass|efficacy demonstrated|nmod|decline decline|nmod|levels levels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 negative|amod|start_entity tested|nmod|negative tested|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 6.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 encoding|dobj|start_entity elucidating|advcl|encoding elucidating|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 action|compound|start_entity inhibition|nmod|action mediated|dobj|inhibition mediated|nsubj|notion notion|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 oxidation|compound|start_entity remained|nsubj|oxidation remained|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 treatment|nmod|start_entity type_2_diabetes_mellitus|nmod|treatment patients|nmod|type_2_diabetes_mellitus efficacy|nmod|patients efficacy|nmod|gemigliptin gemigliptin|appos|inhibitor inhibitor|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 addition|nmod|start_entity increased|nsubj|addition increased|dobj|levels levels|nmod|protein protein|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 release|compound|start_entity involved|nsubjpass|release involved|nmod|upregulation upregulation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 movements|compound|start_entity inducing|nmod|movements inducing|dobj|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 exposure|compound|start_entity inhibited|nmod|exposure inhibited|advcl|resulted resulted|nmod|phosphorylation phosphorylation|dep|change change|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 5.000000 0 12.000000 0 1.000000 0 0.000000 0 0.000000 0 homeostasis|compound|start_entity basal|dobj|homeostasis basal|nsubj|fraction fraction|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 recognition|compound|start_entity process|nmod|recognition role|nmod|process plays|dobj|role plays|nsubj|glucose glucose|acl|phosphorylating phosphorylating|dobj|end_entity 2.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 6.000000 0 1.000000 0 1.000000 0 4.000000 0 0.000000 0 preincubation|nmod|start_entity preincubation|appos|inhibitor inhibitor|nmod|signalling signalling|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 concentration|compound|start_entity decrease|nmod|concentration activates|nsubj|decrease activates|dobj|excretion excretion|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 30.000000 0 0.000000 0 t3|compound|start_entity adrenocorticotropic_hormone|appos|t3 end_entity|nsubj|adrenocorticotropic_hormone 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 promote|dobj|start_entity promote|nsubj|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 generated|parataxis|start_entity generated|dep|resulted resulted|nmod|promotion promotion|acl:relcl|prevented prevented|nmod|addition addition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 start_entity|acl|resulting resulting|nmod|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 showed|nsubj|start_entity showed|advcl|indicating indicating|ccomp|agonist agonist|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 accumulation|amod|start_entity prevent|dobj|accumulation prevent|nmod|medium medium|dep|consequence consequence|nmod|granules granules|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 15.000000 0 0.000000 0 0.000000 0 14.000000 0 0.000000 0 synthesis|compound|start_entity regulation|nmod|synthesis role|nmod|regulation plays|dobj|role plays|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 signaling|amod|start_entity magnitude|nmod|signaling defined|nsubjpass|magnitude defined|nmod|amount amount|acl:relcl|determined determined|nmod|da_transporter da_transporter|appos|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 3.000000 0 homeostasis|compound|start_entity maintenance|nmod|homeostasis underscore|nmod|maintenance underscore|dobj|role role|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 13.000000 0 0.000000 0 disease|amod|start_entity component|nmod|disease component|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 played|nsubj|start_entity indicating|ccomp|played eliminated|advcl|indicating eliminated|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 release|nmod|start_entity inhibited|nsubjpass|release inhibited|nmod|antagonist antagonist|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 link|nmod|start_entity has|dobj|link has|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity study|dobj|effects study|nmod|lipopolysaccharides lipopolysaccharides|dep|expression expression|nmod|production production|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 resistant|nmod|start_entity hydrolysis|amod|resistant rate|nmod|hydrolysis calculated|nmod|rate calculated|nsubjpass|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 level|nmod|start_entity decreased|nsubjpass|level decreased|advcl|perfused perfused|nsubjpass|region region|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 cyclic_monophosphate|appos|start_entity acts|dep|cyclic_monophosphate acts|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 modulate|nsubj|start_entity modulate|dobj|actions actions|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 synthesis|nmod|start_entity impact|nmod|synthesis impact|nmod|abundance abundance|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 response|nmod|start_entity pancreases|nmod|response end_entity|nmod|pancreases 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 dosage|compound|start_entity haplotype|nmod|dosage haplotype|nsubj|* *|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 12-hourly|compound|start_entity treated|nmod|12-hourly treated|nsubjpass|subjects subjects|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 gradient|compound|start_entity increase|nmod|gradient increase|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 resulted|nmod|start_entity resulted|nmod|concentration concentration|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 levels|compound|start_entity led|nsubj|levels led|xcomp|indicating indicating|ccomp|dissociates dissociates|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 correlations|appos|start_entity correlations|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 increased|nsubj|start_entity increased|advcl|inhibited inhibited|nmod|cells cells|acl|expressing expressing|dobj|isoforms isoforms|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 species|compound|start_entity induced|dobj|species monocytes|acl|induced found|nmod|monocytes found|advcl|investigating investigating|dobj|pathways pathways|acl|regulated regulated|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|acl|identified identified|nmod|inhibitor inhibitor|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 indicating|ccomp|start_entity goats|acl|indicating end_entity|nmod|goats 1.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 synthase|amod|start_entity expression|nmod|synthase d-glucose|nmod|expression effects|nmod|d-glucose effects|appos|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 8.000000 0 that|nmod|start_entity activity|nmod|that low|nsubj|activity low|advcl|that that|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 status|compound|start_entity influenced|nmod|status influenced|nsubjpass|components components|nmod|metabolism metabolism|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 sites|dep|start_entity sites|acl:relcl|used used|nsubj|substrates substrates|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 9.000000 0 0.000000 0 0.000000 0 0.000000 0 presence|nmod|start_entity hydroxylated|nmod|presence hydroxylated|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity seem|nsubj|levels increased|ccomp|seem increased|nsubjpass|levels levels|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 reabsorption|compound|start_entity abundance|nmod|reabsorption regulated|nsubjpass|abundance regulated|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 decreased|nsubj|start_entity decreased|xcomp|suggesting suggesting|ccomp|accomplished accomplished|nsubjpass|blockade blockade|nmod|formation formation|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 11.000000 0 0.000000 0 0.000000 0 9.000000 0 1.000000 0 activation|amod|start_entity activation|compound|end_entity 12.000000 0 2.000000 0 98.000000 0 15.000000 0 52.000000 0 68.000000 0 110.000000 0 44.000000 0 21.000000 0 30.000000 0 response|acl|start_entity determined|nmod|response determined|nsubjpass|mutations mutations|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 hydroxylation|nmod|start_entity catalyzes|dobj|hydroxylation catalyzes|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|amod|start_entity higher|nmod|treatment higher|nsubj|increase increase|nmod|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|amod|start_entity inhibitors|nmod|metabolism reduced|nmod|inhibitors reduced|nsubjpass|action action|nmod|rise rise|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 co-therapy|nmod|start_entity reduces|nsubj|co-therapy reduces|dobj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 depletion|compound|start_entity produced|nmod|depletion produced|parataxis|caused caused|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 levels|compound|start_entity observed|nmod|levels diets|advcl|observed diets|nsubj|pattern pattern|acl|emerged emerged|nmod|levels levels|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 production|compound|start_entity regulate|nmod|production regulate|nsubj|cytokines cytokines|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 exposed|nmod|start_entity attenuated|advcl|exposed attenuated|nsubj|binding binding|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 mg/week|appos|start_entity months|dep|mg/week supplemented|nmod|months supplemented|nsubjpass|patients patients|acl:relcl|treated treated|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 biosynthesis|nmod|start_entity activating|nmod|biosynthesis activating|nsubj|receptors receptors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 resistant|nmod|start_entity resistant|advcl|inhibited inhibited|nsubj|production production|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 mg|nmod|start_entity given|dobj|mg given|nmod|measurement measurement|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibits|nsubj|start_entity inhibits|dobj|tumor_necrosis_factor-a tumor_necrosis_factor-a|acl|induced induced|dobj|secretion secretion|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 prevented|nmod|start_entity effect|acl:relcl|prevented rats|appos|effect positive|nmod|rats positive|nmod|mrna mrna|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 substrate|nsubj|start_entity methylated|advcl|substrate methylated|nsubj|inhibitors inhibitors|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|amod|start_entity associated|nmod|treatment toxicity|acl|associated mitigating|dobj|toxicity demonstrate|advcl|mitigating demonstrate|dobj|importance importance|nmod|screening screening|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 start_entity|nmod|mutation mutation|nmod|gene gene|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 release|compound|start_entity investigate|nmod|release investigate|dobj|action action|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 acquisition|nmod|start_entity involve|nsubj|acquisition involve|dobj|receptor receptor|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 element|compound|start_entity element|dep|phosphorylation phosphorylation|amod|binding binding|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 resistance|compound|start_entity marker|nmod|resistance shown|xcomp|marker end_entity|acl:relcl|shown 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 homeostasis|compound|start_entity maintaining|dobj|homeostasis plays|advcl|maintaining plays|nsubj|binding binding|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 concentration|amod|start_entity influence|nmod|concentration influence|nmod|patterns patterns|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 10.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 compared|xcomp|start_entity theatment|acl|compared level|nmod|theatment level|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 production|compound|start_entity rate|nmod|production contribute|nmod|rate contribute|nsubj|overexpression overexpression|nmod|subunit subunit|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transport|amod|start_entity blocked|dobj|transport blocked|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 10.000000 0 0.000000 0 1.000000 0 synthesized|nmod|start_entity synthesized|advcl|using using|nsubj|inhibitors inhibitors|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 induction|nmod|start_entity is|nsubj|induction dependent|advcl|is dependent|nsubj|induction induction|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 status|amod|start_entity value|nmod|status improved|nsubjpass|value improved|nmod|evaluation evaluation|nmod|bcl2 bcl2|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 led|nsubj|start_entity led|nmod|lines lines|nmod|levels levels|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 phosphorylation|amod|start_entity blocking|dobj|phosphorylation signaling|advcl|blocking end_entity|acl|signaling 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 nebicapone|appos|start_entity nebicapone|appos|inhibitor inhibitor|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 absence|nmod|start_entity controls|dep|absence free|advcl|controls free|nsubj|induction induction|nmod|synthesis synthesis|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 was|nmod|start_entity was|nsubj|increase increase|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 phosphorylation|amod|start_entity phosphorylation|nmod|tbetar-ii tbetar-ii|appos|reaction reaction|acl|mediated mediated|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 inhibition|nmod|start_entity attenuated|nsubj|inhibition attenuated|dobj|activation activation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 unaffected|nmod|start_entity induced|xcomp|unaffected induced|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 readministration|nmod|start_entity sustained|nmod|readministration sustained|advcl|changes changes|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 profiles|nmod|start_entity analysed|nsubjpass|profiles analysed|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 levels|compound|start_entity decreased|nsubj|levels decreased|advcl|stimulated stimulated|nsubjpass|fibroblasts fibroblasts|acl|expressing expressing|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 concentrations|nmod|start_entity had|dobj|concentrations had|nsubj|patients patients|acl:relcl|received received|nmod|donor donor|acl|expressing expressing|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 free|xcomp|start_entity delineated|parataxis|free delineated|dobj|mechanisms mechanisms|acl:relcl|controlled controlled|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 glutathione|appos|start_entity malondialdehyde|appos|glutathione malondialdehyde|appos|dismutase dismutase|appos|glutathione_s-transferase glutathione_s-transferase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 receptor|amod|start_entity decrease|nmod|receptor memory_deficits|nmod|decrease memory_deficits|dobj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|nmod|start_entity suggesting|nmod|uptake localized|xcomp|suggesting localized|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 1.000000 0 inhibition|advcl|start_entity susceptible|xcomp|inhibition susceptible|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 characteristic|compound|start_entity end_entity|appos|characteristic 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 homeostasis|compound|start_entity homeostasis|nmod|end_entity 2.000000 0 0.000000 0 10.000000 0 7.000000 0 4.000000 0 154.000000 0 0.000000 0 62.000000 0 324.000000 1 2.000000 0 intact|amod|start_entity hormone|amod|intact serum|dobj|hormone investigated|advcl|serum investigated|dobj|polymorphisms polymorphisms|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|amod|start_entity perturbation|nmod|metabolism accompanied|nmod|perturbation accompanied|nsubjpass|loss loss|nmod|agents agents|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 residues|amod|start_entity phosphorylated|nmod|residues phosphorylated|nsubjpass|plc-y plc-y|appos|pp125fak pp125fak|appos|p59fyn p59fyn|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 deliver|dobj|start_entity glycoprotein|ccomp|deliver glycoprotein|nsubj|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 dose|nmod|start_entity evaluate|nmod|dose evaluate|dobj|efficacy efficacy|nmod|priming priming|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 emulsion|compound|start_entity vitro|nmod|emulsion determined|advcl|vitro determined|nsubjpass|parameters parameters|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 handling|compound|start_entity concentration|nmod|handling investigated|nsubjpass|concentration investigated|nmod|dogs dogs|nmod|control control|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 8.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 patients|compound|start_entity genotype|nmod|patients genotype|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 effects|nmod|start_entity effects|acl:relcl|used used|nmod|kinetics kinetics|nmod|solutions solutions|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthesis|amod|start_entity step|nmod|synthesis catalyzes|dobj|step enzyme|acl:relcl|catalyzes enzyme|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 re-uptake|nmod|start_entity mediates|dobj|re-uptake mediates|nsubj|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 sensitivity|compound|start_entity sensitivity|nmod|bone bone|acl|inhibiting inhibiting|xcomp|alpha alpha|nsubj|end_entity 2.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 8.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 blocks|nsubj|start_entity blocks|dobj|assembly assembly|acl:relcl|bound bound|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 prostaglandin_e|appos|start_entity celecoxib|nmod|prostaglandin_e celecoxib|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 flibanserin|nmod|start_entity flibanserin|amod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 channel|compound|start_entity encoding|dobj|channel revealed|xcomp|encoding revealed|dobj|presence presence|nmod|gene gene|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 regulated|nmod|start_entity regulated|nsubjpass|differentiation differentiation|nmod|cd8 cd8|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 mutations|amod|start_entity bearing|dobj|mutations subclones|advcl|bearing subclones|xcomp|containing containing|ccomp|emerge emerge|nsubj|mutation mutation|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 5.000000 0 12.000000 0 1.000000 0 0.000000 0 0.000000 0 <|nsubj|start_entity benefit|acl:relcl|< conferred|dobj|benefit conferred|nsubj|inhibition inhibition|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 included|dobj|start_entity included|nmod|agonist agonist|compound|end_entity 3.000000 0 0.000000 0 10.000000 0 1.000000 0 0.000000 0 4.000000 0 1.000000 0 3.000000 0 1.000000 0 0.000000 0 phosphorylation|compound|start_entity enhanced|nsubjpass|phosphorylation enhanced|parataxis|activates activates|nmod|absence absence|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 sti-571|appos|start_entity induces|nsubj|sti-571 induces|nmod|inhibition inhibition|nmod|protein protein|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 0.000000 0 ly294002|amod|start_entity inhibited|nmod|ly294002 inhibited|nsubjpass|phosphorylation phosphorylation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 decrease|nmod|start_entity decrease|nmod|immunoreactivity immunoreactivity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 administration|amod|start_entity h|nmod|administration h|nsubj|levels levels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2,3,5,6|amod|start_entity using|dobj|2,3,5,6 synthesized|xcomp|using synthesized|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 toxicity|amod|start_entity prevents|dobj|toxicity prevents|nsubj|brain-derived_neurotrophic_factor brain-derived_neurotrophic_factor|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 antibiotic|nsubj|start_entity antibiotic|acl:relcl|inhibits inhibits|dobj|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 11.000000 0 0.000000 0 2.000000 0 0.000000 0 linked|nsubjpass|start_entity linked|nmod|transferrin transferrin|acl|synthesized synthesized|nmod|cells cells|acl|followed followed|nmod|neurons neurons|acl|expressing expressing|dobj|receptors receptors|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 start_entity|advcl|competing competing|nmod|membranes membranes|acl|prepared prepared|advcl|expressing expressing|dobj|receptor receptor|compound|end_entity 1.000000 0 0.000000 0 4.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 system|compound|start_entity activates|dobj|system activates|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 effects|nmod|start_entity determine|dobj|effects determine|nmod|patients patients|nmod|dcis dcis|nummod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 2.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|dep|ic ic|nsubj|enzyme enzyme|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 stimulation|compound|start_entity expression|nsubj|stimulation expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity nullified|nsubjpass|effects nullified|nmod|antibody antibody|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthesizing|nmod|start_entity promotes|advcl|synthesizing promotes|nsubj|cyclooxygenase-2 cyclooxygenase-2|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 explaining|nmod|start_entity this|acl|explaining raised|dobj|this raised|nsubjpass|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 greater|nmod|start_entity greater|nsubj|magnitude magnitude|nmod|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 doses|nmod|start_entity induced|nmod|doses induced|nsubj|signaling signaling|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 transport|compound|start_entity exhibit|dobj|transport tissues|acl:relcl|exhibit isoform|nmod|tissues isoform|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 16.000000 0 2.000000 0 0.000000 0 blocked|nmod|start_entity blocked|nsubjpass|pathway pathway|compound|end_entity 0.000000 0 1.000000 0 1.000000 0 1.000000 0 9.000000 0 13.000000 0 40.000000 0 2.000000 0 2.000000 0 1.000000 0 addition|nmod|start_entity stimulated|nmod|addition stimulated|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 analysis|amod|start_entity transformants|nsubj|analysis transformants|xcomp|expressing expressing|ccomp|showed showed|nsubj|gene gene|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 concentrations|compound|start_entity hxt7|nmod|concentrations end_entity|nmod|hxt7 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 production|amod|start_entity inducing|dobj|production exert|advcl|inducing exert|nsubj|interleukin-1_beta interleukin-1_beta|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 20-hydroxyvitamin_d3|amod|start_entity metabolizes|xcomp|20-hydroxyvitamin_d3 metabolizes|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|advcl|activity activity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 dolichols|compound|start_entity formation|nmod|dolichols precursor|nmod|formation serves|nmod|precursor importance|advcl|serves importance|nsubj|regulation regulation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pathway|amod|start_entity affect|dobj|pathway enzyme|acl:relcl|affect enzyme|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transmission|amod|start_entity control|nmod|transmission explore|nmod|control studied|advcl|explore studied|dobj|expression expression|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 tests|nummod|start_entity reported|nmod|tests favor|advcl|reported favor|parataxis|decreases decreases|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 status|amod|start_entity marker|nmod|status end_entity|nmod|marker 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 deficiency|amod|start_entity up-regulated|nmod|deficiency up-regulated|nmod|resistance resistance|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 flux|nmod|start_entity regulate|dobj|flux regulate|nsubj|two two|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 30.000000 0 0.000000 0 response|compound|start_entity lower|nsubj|response lower|advcl|enhanced enhanced|nsubjpass|response response|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 8.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 performed|nmod|start_entity performed|advcl|test test|dobj|role role|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 use|nmod|start_entity use|acl:relcl|inhibits inhibits|dobj|properties properties|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 chaperone|compound|start_entity chaperone|acl|delivering delivering|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 1.000000 0 0.000000 0 bradykinin|dep|start_entity bradykinin|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 levels|nmod|start_entity levels|acl|associated associated|nmod|mass mass|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 mitigate|nmod|start_entity mitigate|nsubj|pretreatment pretreatment|nmod|dose dose|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 7.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 dehydrogenase|amod|start_entity kinase|appos|dehydrogenase aspartate_aminotransferase|nsubj|kinase aspartate_aminotransferase|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 relationship|nmod|start_entity relationship|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 5.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 resistance|compound|start_entity mechanism|nmod|resistance explore|dobj|mechanism explore|nsubj|inhibitors inhibitors|compound|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 production|compound|start_entity decreased|dobj|production levels|dep|decreased reduced|nmod|levels reduced|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 analog|compound|start_entity means|nmod|analog modification|nmod|means modification|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 addicts|compound|start_entity system|nmod|addicts system|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 cortisol|nmod|start_entity suppression|nmod|cortisol patient|nmod|suppression demonstrated|nsubj|patient demonstrated|dobj|lack lack|nmod|suppression suppression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 start_entity|nsubj|study study|nmod|protein protein|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 et-1|appos|start_entity induced|nmod|et-1 phosphorylation|acl|induced phosphorylation|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptor|amod|start_entity activation|nmod|receptor mice|nmod|activation /|dep|mice rescue|dep|/ rescue|nmod|healing healing|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 decreases|nsubj|start_entity decreases|xcomp|beta-amyloid beta-amyloid|advcl|regulating regulating|dobj|transcription transcription|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity known|nmod|effect known|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 current|compound|start_entity %|nmod|current accounted|nmod|% patches|acl|accounted isolated|nmod|patches isolated|nsubj|currents currents|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 dehydrogenase-2|compound|start_entity dehydrogenase-2|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 18.000000 0 2.000000 0 59.000000 0 induces|nsubj|start_entity induces|dobj|expression expression|nmod|manner manner|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 permeability|compound|start_entity mimicked|nmod|permeability mimicked|dobj|effect effect|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 ligand|dobj|start_entity ligand|nsubj|effects effects|nmod|end_entity 12.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 peak|nmod|start_entity used|dobj|peak appeared|advcl|used appeared|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 control|nmod|start_entity investigate|dobj|control investigate|advcl|induced induced|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 3.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 responses|amod|start_entity greater|nsubj|responses greater|nmod|pmol/kg/min pmol/kg/min|amod|dopamine dopamine|nmod|doses doses|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 radioimmunoassayed|nsubjpass|start_entity measured|parataxis|radioimmunoassayed measured|nsubjpass|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 12.000000 0 2.000000 0 0.000000 0 6.000000 0 0.000000 0 storage|compound|start_entity due|nmod|storage due|nmod|rate rate|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 synthases|amod|start_entity inhibitor|nmod|synthases ng-nitro-l-arginine|dep|inhibitor presence|nmod|ng-nitro-l-arginine shifted|nmod|presence shifted|nsubjpass|curves curves|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 antagonizes|nsubj|start_entity enhances|advcl|antagonizes end_entity|acl:relcl|enhances 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 therapy|compound|start_entity added|nmod|therapy added|nsubj|efficacy efficacy|nmod|sitagliptin sitagliptin|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|xcomp|alveolarization alveolarization|nsubj|levels levels|nmod|vascular_endothelial_growth_factor vascular_endothelial_growth_factor|appos|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 -lsb-|nsubj|start_entity -lsb-|dobj|inhibitor inhibitor|acl|enhancing enhancing|dobj|factor factor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 concentration|compound|start_entity surface|dobj|concentration surface|nsubj|activity activity|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 13.000000 0 2.000000 0 0.000000 0 structures|amod|start_entity receptor|nmod|structures acting|nmod|receptor eliciting|advcl|acting participates|xcomp|eliciting participates|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 blockers|compound|start_entity blockers|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|compound|start_entity regulates|dobj|metabolism playing|advcl|regulates protein|acl|playing protein|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 1.000000 0 0.000000 0 tension|compound|start_entity restricted|nmod|tension restricted|nsubjpass|function function|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 test|compound|start_entity clinical|appos|test clinical|appos|calculation calculation|nmod|indexes indexes|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 triterpenoid|appos|start_entity has|nsubj|triterpenoid has|dobj|ability ability|acl|upregulate upregulate|dobj|proteins proteins|nmod|induction induction|nmod|pathway pathway|appos|end_entity 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptors|compound|start_entity receptors|dep|glur1 glur1|appos|end_entity 0.000000 0 0.000000 0 14.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 hormones|nmod|start_entity regulate|nsubj|hormones regulate|dobj|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 response|nmod|start_entity showed|nmod|response showed|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 sphingomyelin|acl|start_entity conversion|nmod|sphingomyelin activates|nsubj|conversion activates|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 composition|amod|start_entity shown|nsubjpass|composition shown|parataxis|similar similar|advcl|found found|nmod|peptide peptide|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|amod|start_entity weeks|nmod|treatment downregulated|nmod|weeks downregulated|nsubjpass|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 ions|nsubj|start_entity transport|xcomp|ions transport|nsubj|function function|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 i|amod|start_entity transporter|nsubj|i transporter|dobj|proteins proteins|nummod|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 23.000000 0 2.000000 0 1.000000 0 currents|compound|start_entity cuo|nmod|currents particles|nmod|cuo effects|nmod|particles studied|nsubjpass|effects studied|nmod|neurons neurons|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 rise|nmod|start_entity cause|dobj|rise cause|advcl|seen seen|nmod|use use|nmod|agonists agonists|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inability|nmod|start_entity inability|acl|stimulate stimulate|dobj|release release|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 efflux|compound|start_entity promote|dobj|efflux account|advcl|promote account|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 5-fluorouracil|appos|start_entity used|nmod|5-fluorouracil used|nsubjpass|irinotecan irinotecan|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity microvascular|nsubj|effect produced|advcl|microvascular produced|nsubj|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 concentrations|nmod|start_entity combination|nmod|concentrations cells|nmod|combination treatment|nmod|cells enhanced|nsubj|treatment enhanced|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity investigated|dobj|effect investigated|advcl|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity menstrual|nmod|treatment menstrual|dobj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 12.000000 0 2.000000 0 0.000000 0 6.000000 0 0.000000 0 therapy|compound|start_entity testosterone|nmod|therapy levels|nmod|testosterone face|nmod|levels vital|nmod|face vital|nsubj|androgen_receptor androgen_receptor|appos|end_entity 1.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 inhibition|amod|start_entity emphasis|nmod|inhibition focuses|nmod|emphasis focuses|nmod|inhibition inhibition|amod|particular particular|nmod|data data|nmod|end_entity 0.000000 0 0.000000 0 7.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 outflow|amod|start_entity investigated|nmod|outflow investigated|nmod|receptors receptors|nummod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibition|amod|start_entity inhibition|nmod|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 chelates|compound|start_entity stimulate|nsubj|chelates stimulate|dobj|release release|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transporter|nsubj|start_entity transporter|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 concentrations|amod|start_entity correlates|nmod|concentrations correlates|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 stimulates|nsubj|start_entity stimulates|dobj|trafficking trafficking|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 10.000000 0 2.000000 0 0.000000 0 changes|amod|start_entity changes|appos|independent independent|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 8.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 levels|compound|start_entity measured|nsubjpass|levels measured|nmod|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effect|nmod|start_entity examined|dobj|effect examined|advcl|assess assess|dobj|interaction interaction|nmod|end_entity 3.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 species|compound|start_entity essential|nsubj|species show|ccomp|essential show|advcl|using using|advcl|lacking lacking|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 responses|nummod|start_entity antagonists|nmod|responses end_entity|dep|antagonists 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 treatment|amod|start_entity effects|nmod|treatment examined|dobj|effects examined|nmod|release release|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 start_entity|dobj|receptor-alpha receptor-alpha|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 regulated|nmod|start_entity regulated|nsubjpass|binding binding|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 utilization|compound|start_entity selective|nmod|utilization appears|xcomp|selective appears|nsubj|resistance resistance|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 changes|nmod|start_entity involved|nsubjpass|changes involved|nmod|mechanism mechanism|nmod|action action|nmod|inhibition inhibition|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 storage|compound|start_entity organ|nmod|storage organ|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 11.000000 0 0.000000 0 4.000000 0 12.000000 0 1.000000 0 markers|nmod|start_entity end_entity|nmod|markers 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 11.000000 0 0.000000 0 1.000000 0 0.000000 0 index|appos|start_entity index|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 sdf-1|amod|start_entity chemotaxis|nmod|sdf-1 controls|dobj|chemotaxis controls|advcl|regulating regulating|dobj|expression expression|nmod|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 l-alpha-amino-3-hydroxy-5-methyl-4-isoxazelopropionate|appos|start_entity l-alpha-amino-3-hydroxy-5-methyl-4-isoxazelopropionate|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|compound|start_entity reduces|dobj|uptake reduces|nsubj|treatment treatment|nmod|sb203580 sb203580|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthesis|compound|start_entity abolished|dobj|synthesis abolished|advcl|suggesting suggesting|ccomp|associated associated|nmod|activation activation|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 index|compound|start_entity reduction|nmod|index concentration|dep|reduction concentration|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 activity|amod|start_entity stimulation|nmod|activity function|nsubj|stimulation function|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nmod|vivo vivo|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 monomers|amod|start_entity induced|nmod|monomers end_entity|acl|induced 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 affect|nsubj|start_entity affect|dobj|targets targets|nmod|nampt nampt|dep|end_entity 6.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 levels|compound|start_entity control|dobj|levels report|advcl|control report|dobj|inability inability|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 action|nmod|start_entity subsets|nmod|action exert|dobj|subsets induced|advcl|exert coactivators|acl:relcl|induced examined|nmod|coactivators examined|dobj|interaction interaction|nmod|end_entity 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 3.000000 0 0.000000 0 6.000000 0 treatment|compound|start_entity induced|nmod|treatment induced|nsubjpass|enrichment enrichment|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 response|nmod|start_entity receptors|nmod|response contributions|nmod|receptors examined|nsubjpass|contributions examined|nmod|antagonists antagonists|compound|end_entity 0.000000 0 0.000000 0 16.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 start_entity|appos|breast_cancer breast_cancer|amod|her2-negative her2-negative|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|acl:relcl|utilized utilized|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 absence|nmod|start_entity grown|nmod|absence grown|advcl|differed differed|nsubj|rate rate|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 concentration|compound|start_entity increasing|dobj|concentration alter|csubj|increasing alter|dobj|effect effect|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 18.000000 0 0.000000 0 regulated|nmod|start_entity regulated|nsubjpass|abundance abundance|appos|flavoprotein flavoprotein|acl|needed needed|nmod|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 currents|compound|start_entity depresses|dobj|currents depresses|nmod|neurons neurons|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 infusion|amod|start_entity e.g.|nmod|infusion used|nsubjpass|e.g. used|advcl|changed changed|nsubjpass|binding binding|nmod|cortisone cortisone|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 similarity|amod|start_entity similarity|nmod|receptor receptor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 production|compound|start_entity decreasing|dobj|production inhibited|advcl|decreasing inhibited|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 agonist|appos|start_entity advantage|nmod|agonist taken|dobj|advantage taken|advcl|evaluate evaluate|dobj|role role|nmod|receptors receptors|nummod|end_entity 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 superior|nsubj|start_entity superior|nmod|activation activation|nmod|n-nitrosopyrrolidine n-nitrosopyrrolidine|appos|substrate substrate|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|nmod|start_entity cured|nmod|treatment cured|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 single|nmod|start_entity single|nsubj|gln11leu gln11leu|compound|end_entity 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity determine|dobj|effect determine|nmod|excretion excretion|nmod|toxins toxins|acl|mediated mediated|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 detecting|nmod|start_entity promising|advcl|detecting promising|nsubj|measurement measurement|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 12-o-tetradecanoylphorbol-13-acetate|compound|start_entity incubated|nmod|12-o-tetradecanoylphorbol-13-acetate incubated|xcomp|regulate regulate|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nsubj|levels levels|nmod|gene gene|nummod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitors|nmod|start_entity represent|nsubj|inhibitors represent|dobj|options options|acl|recommended recommended|nmod|tumors tumors|acl|produced produced|advcl|activating activating|nmod|coding coding|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 8.000000 0 0.000000 0 0.000000 0 0.000000 0 activation|amod|start_entity blockade|nmod|activation relate|nmod|blockade relate|nsubj|effects effects|nmod|antagonism antagonism|compound|end_entity 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 type|nmod|start_entity relation|nmod|type relation|nmod|resistance resistance|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 production|amod|start_entity associated|nmod|production associated|nsubjpass|regulation regulation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 conversion|acl|start_entity vitamin_b|dep|conversion catalyzes|dobj|vitamin_b catalyzes|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 production|amod|start_entity demonstration|nmod|production analogous|dep|demonstration analogous|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 synthesis|appos|start_entity increase|nmod|synthesis accompanied|nmod|increase accompanied|nsubjpass|induction induction|nmod|expression expression|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 combining|dobj|start_entity death|acl|combining induction|nmod|death adenovirus|nsubj|induction adenovirus|xcomp|carrying carrying|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 -lsb-|compound|start_entity increase|nmod|-lsb- interfere|nmod|increase concentrations|acl:relcl|interfere inhibited|nmod|concentrations inhibited|dobj|production production|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 measured|nsubjpass|start_entity measured|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 n2|compound|start_entity n2|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 production|amod|start_entity assess|nmod|production assess|dobj|effects effects|nmod|inhibitors inhibitors|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pocket|compound|start_entity binding|nmod|pocket inhibit|nmod|binding inhibit|dobj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentration|compound|start_entity increases|nmod|concentration occur|nmod|increases occur|nsubj|increases increases|nmod|activity activity|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 production|amod|start_entity enhancing|dobj|production role|acl|enhancing mediated|nmod|role role|acl|mediated plays|dobj|role plays|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 salts|nmod|start_entity addition|nmod|salts reduced|nsubj|addition reduced|dobj|loss loss|acl:relcl|treated treated|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentration|nmod|start_entity suppress|nsubj|concentration suppress|dobj|release release|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 18.000000 0 0.000000 0 phosphorylation|nmod|start_entity increase|nmod|phosphorylation preceded|nsubj|increase preceded|dobj|growth growth|acl|induced induced|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transport|compound|start_entity ischemia|nmod|transport due|nmod|ischemia cotransporter|amod|due effects|nmod|cotransporter effects|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 solutions|compound|start_entity sedimentation|nmod|solutions sedimentation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 accumulation|compound|start_entity accumulation|acl:relcl|associated associated|nmod|expression expression|nmod|transporter transporter|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 mlk|nmod|start_entity activation|nmod|mlk reveals|nsubj|activation reveals|xcomp|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 stimulates|compound|start_entity endogenous|nsubj|stimulates endogenous|dobj|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 derivatives|amod|start_entity inhibited|nsubj|derivatives inhibited|dobj|signals signals|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 triggers|nsubj|start_entity stimulates|advcl|triggers stimulates|nsubj|cholecystokinin cholecystokinin|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptors|compound|start_entity named|nsubj|receptors named|ccomp|identified identified|nsubjpass|er-alpha er-alpha|appos|end_entity 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 attenuated|nmod|start_entity promoted|parataxis|attenuated promoted|ccomp|knockdown knockdown|nsubj|proliferation proliferation|nmod|cells cells|appos|phosphorylation phosphorylation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 2.000000 0 10.000000 0 0.000000 0 0.000000 0 0.000000 0 reuptake|amod|start_entity responsible|nmod|reuptake dopamine_transporter|amod|responsible dopamine_transporter|appos|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 3.000000 0 sensitive|nmod|start_entity sensitive|parataxis|raises raises|dobj|activity activity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 dose|nmod|start_entity reduced|nsubjpass|dose showed|advcl|reduced showed|nmod|concentrations concentrations|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 kinase|amod|start_entity receptor|appos|kinase binding|nmod|receptor c-kit|amod|binding exerts|nmod|c-kit exerts|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 therapy|amod|start_entity relevance|nmod|therapy relevance|nmod|polymorphism polymorphism|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 accumulation|compound|start_entity affected|nmod|accumulation pkc|dep|affected cyclase|nmod|pkc regulated|nmod|cyclase regulated|nsubjpass|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 absence|nmod|start_entity decreased|nmod|absence decreased|nsubjpass|production production|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|appos|cialis cialis|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|acl|induced induced|dobj|expression expression|nmod|gene gene|compound|end_entity 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptor|amod|start_entity derived|nmod|receptor end_entity|acl|derived 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 blasts|compound|start_entity showed|nsubj|blasts showed|dobj|accumulation accumulation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 exposure|compound|start_entity pts|nmod|exposure number|nmod|pts respond|nsubj|number respond|nmod|indicative indicative|nmod|inhibition inhibition|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptors|compound|start_entity role|nmod|receptors role|dep|cp cp|appos|antagonist antagonist|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 withdrawal|nmod|start_entity highlighted|nsubj|withdrawal highlighted|dobj|concerns concerns|nmod|safety safety|nmod|inhibitors inhibitors|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 decreased|nmod|start_entity action|acl|decreased action|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 lys-296|amod|start_entity gly|dep|lys-296 mutations|dep|gly affect|nsubj|mutations affect|dobj|interaction interaction|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity compare|dobj|effects compare|nmod|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 tension|compound|start_entity attenuated|nmod|tension attenuated|xcomp|indicating indicating|dobj|modulation modulation|nmod|production production|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nmod|sarcoma sarcoma|nmod:poss|ewing ewing|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 secretion|amod|start_entity effect|nmod|secretion effect|dep|effect effect|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 changes|nmod|start_entity explained|nmod|changes explained|nsubjpass|activation activation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 cyp2b|nmod|start_entity inhibited|advcl|cyp2b inhibited|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 shown|advmod|start_entity shown|nsubjpass|administration administration|nmod|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 group|amod|start_entity oxidizing|dobj|group detoxifies|advcl|oxidizing detoxifies|nsubj|2 2|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 8.000000 0 targets|compound|start_entity achieve|dobj|targets achieve|nmod|-rsb- -rsb-|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 evoked|nsubj|start_entity evoked|dobj|current current|acl:relcl|similar similar|nmod|that that|nmod|presence presence|nmod|+ +|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 s-transferase|amod|start_entity demonstrated|nsubj|s-transferase demonstrated|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 daily|amod|start_entity inhibitor|dep|daily inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 0.000000 0 diminished|nsubj|start_entity diminished|advcl|restored restored|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 influenced|advcl|start_entity influenced|dobj|response response|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 ability|nmod|start_entity trait|nsubj|ability trait|acl|mediated mediated|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 trna|nsubj|start_entity trna|ccomp|serves serves|nmod|site site|nmod|biosynthesis biosynthesis|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 kinase|compound|start_entity kinase|nsubj|importance importance|nmod|field field|dep|lck lck|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 inhibited|nsubj|start_entity inhibited|parataxis|eliminating eliminating|dobj|trafficking trafficking|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 addition|nmod|start_entity obtained|nmod|addition blockade|acl|obtained blockade|amod|end_entity 0.000000 0 2.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 efficacy|amod|start_entity determinant|nmod|efficacy determinant|nsubj|192q/q 192q/q|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nmod|sp600125 sp600125|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 glucagon|nmod|start_entity end_entity|appos|glucagon 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 receiving|xcomp|start_entity polymorphisms|acl|receiving polymorphisms|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 essential|nmod|start_entity essential|nsubj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 affected|nsubj|start_entity affected|parataxis|ameliorated ameliorated|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 tracts|compound|start_entity blocked|nmod|tracts blocked|nmod|presence presence|nmod|fragment fragment|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 administration|nmod|start_entity prior|nmod|administration d|advmod|prior dl-a-difluoromethylornithine|nmod|d treated|nmod|dl-a-difluoromethylornithine reduced|advcl|treated reduced|advcl|inactivated inactivated|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 focused|nmod|start_entity focused|nsubj|receptors receptors|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 production|compound|start_entity affects|dobj|production affects|nsubj|tumor_necrosis_factor tumor_necrosis_factor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 amk|nmod|start_entity metabolite|nsubj|amk metabolite|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transfer|compound|start_entity initiate|dobj|transfer complexes|acl:relcl|initiate targeting|nmod|complexes sequence|acl|targeting includes|dobj|sequence includes|nsubj|domain domain|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 conductance|compound|start_entity rectifying|dobj|conductance rectifying|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 start_entity|nmod|glycoproteins glycoproteins|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 correlated|nsubj|start_entity correlated|advcl|plasma plasma|dobj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 death|amod|start_entity protected|nmod|death showed|ccomp|protected showed|parataxis|connected connected|nmod|influence influence|nmod|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthesis|compound|start_entity inhibit|dobj|synthesis inhibit|nmod|level level|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 inhibitor|appos|start_entity followed|nmod|inhibitor egfr|acl|followed phosphorylation/activation|nmod|egfr suggested|nsubj|phosphorylation/activation suggested|ccomp|element element|nsubj|activation activation|nmod|end_entity 0.000000 0 2.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 13.000000 0 0.000000 0 0.000000 0 0.000000 0 role|nmod|start_entity investigated|dobj|role investigated|parataxis|induced induced|dobj|formation formation|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 species|nmod|start_entity cholesteryl_ester_transfer_protein|nmod|species cholesteryl_ester_transfer_protein|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 supplementation|amod|start_entity effects|nmod|supplementation explore|dobj|effects explore|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 agonists|amod|start_entity agonists|nmod|secretion secretion|acl|stimulated stimulated|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 transport|compound|start_entity enhancing|dobj|transport compensates|advcl|enhancing deprivation|acl:relcl|compensates protect|nmod|deprivation protect|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 peramivir|appos|start_entity removed|appos|peramivir removed|dep|properties properties|nmod|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 blocked|nmod|start_entity blocked|ccomp|surface surface|dobj|binding binding|appos|end_entity 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 8.000000 0 0.000000 0 1.000000 0 0.000000 0 agents|amod|start_entity suboptimal|nmod|agents suboptimal|advcl|undergoing undergoing|dobj|percutaneous percutaneous|dep|intervention intervention|dep|antagonism antagonism|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 receptors|compound|start_entity containing|dobj|receptors end_entity|acl|containing 0.000000 0 0.000000 0 202.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 20.000000 0 5.000000 0 0.000000 0 synthase|amod|start_entity expression|amod|synthase pathway|nmod|expression pathway|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 mutants|amod|start_entity mutants|amod|dependent dependent|nmod:npmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 nh2|amod|start_entity doses|nmod|nh2 increased|nmod|doses increased|nsubj|area area|nmod|curve curve|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 response|nmod|start_entity assessment|nmod|response tool|nsubj|assessment tool|advcl|shown shown|xcomp|affect affect|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 activity|nmod|start_entity investigate|dobj|activity investigate|nmod|methylation methylation|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nsubj|ratio ratio|nmod|availability availability|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 4.000000 0 kinase|compound|start_entity encodes|dobj|kinase encodes|nsubj|oncogene oncogene|amod|end_entity 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 load|compound|start_entity disposal|nmod|load promoting|dobj|disposal measured|advcl|promoting measured|dobj|efficacy efficacy|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 index|nmod|start_entity baclofen|appos|index magnitude|nmod|baclofen magnitude|nmod|response response|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 synthase|amod|start_entity expression|nmod|synthase prohibiting|dobj|expression protect|advcl|prohibiting protect|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 dose|nmod|start_entity showed|advcl|dose showed|dobj|reduction reduction|nmod|mmp-9 mmp-9|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 compared|xcomp|start_entity iron_sucrose|acl|compared examine|advcl|iron_sucrose examine|dobj|effectiveness effectiveness|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 oxiation|compound|start_entity found|nmod|oxiation found|nmod|production production|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 allyl-isothiocyanate|appos|start_entity allyl-isothiocyanate|compound|end_entity 6.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 role|nmod|start_entity indicating|dobj|role found|xcomp|indicating found|nmod|variants variants|nmod|end_entity 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 3.000000 0 start_entity|appos|androgen androgen|acl:relcl|activates activates|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 reversed|nsubj|start_entity reversed|ccomp|release release|nsubj|suppression suppression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 reduced|iobj|start_entity reduced|dobj|macrophages macrophages|acl|stimulated stimulated|advcl|observed observed|nsubj|influence influence|nmod|activity activity|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 5.000000 0 2.000000 0 10.000000 0 antagonist|nsubj|start_entity suggesting|ccomp|antagonist suggesting|nsubj|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 agonist|amod|start_entity investigated|nmod|agonist investigated|nmod|response response|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 level|compound|start_entity equal|nmod|level concentration|amod|equal solution|nmod|concentration pancreatico-duodenal_artery|nmod|solution infusion|nmod|pancreatico-duodenal_artery evoke|nsubj|infusion evoke|dobj|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 mutations|nmod|start_entity kinase|nsubj|mutations kinase|parataxis|reported reported|nsubjpass|mutation mutation|compound|end_entity 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 approved|nsubjpass|start_entity approved|nmod|non-small-cell_lung_cancer non-small-cell_lung_cancer|acl:relcl|detected detected|dobj|tumours tumours|nmod|exon exon|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitors|amod|start_entity inhibitors|nmod|activation activation|compound|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 dependent|dep|start_entity dependent|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 5.000000 0 1.000000 0 7.000000 0 phosphorylation|compound|start_entity required|nmod|phosphorylation mediated|advcl|required mediated|nsubj|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 involve|nmod|start_entity involve|dobj|availability availability|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 losses|compound|start_entity increased|dobj|losses increased|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 18.000000 0 0.000000 0 factor|compound|start_entity mediated|nmod|factor ras|acl|mediated ras|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 alters|nsubj|start_entity alters|dobj|activities activities|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 0.000000 0 e.g.|dep|start_entity camp|dep|e.g. blocked|nsubj|camp blocked|dobj|induction induction|nmod|synthesis synthesis|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 inhibits|nsubj|start_entity investigate|advcl|inhibits examined|advcl|investigate examined|dobj|activation activation|nmod|kinases kinases|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 that|nmod|start_entity compared|nmod|that compared|dobj|effects effects|nmod|sirna sirna|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|amod|start_entity interfering|nmod|treatment using|advcl|interfering mcl-1|acl|using knockdown|nmod|mcl-1 sensitized|nsubj|knockdown sensitized|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 impair|dobj|start_entity domain|acl:relcl|impair domain|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 2.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibit|nsubj|start_entity inhibit|dobj|h_quinone_oxidoreductase_1 h_quinone_oxidoreductase_1|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 level|nmod|start_entity independent|nmod|level atherosclerosis|amod|independent inhibit|dobj|atherosclerosis apolipoprotein_a-i|advcl|inhibit apolipoprotein_a-i|dobj|functions functions|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 cl/f|compound|start_entity higher|nsubj|cl/f higher|nmod|carriers carriers|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 proteins|amod|start_entity relationship|nmod|proteins investigating|dobj|relationship model|acl|investigating model|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 group|compound|start_entity greater|nmod|group greater|nsubj|reduction reduction|nmod|level level|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 daunorubicin|appos|start_entity cells|dep|daunorubicin rejected|nmod|cells drugs|acl|rejected favor|nsubj|drugs atp|advcl|favor insensitive|xcomp|atp state|acl:relcl|insensitive end_entity|nmod|state 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 response|acl|start_entity production|dep|response production|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 enhanced|dobj|start_entity enhanced|advcl|indicating indicating|dobj|specificity specificity|nmod|responsiveness responsiveness|acl|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 phosphorylation|compound|start_entity reduced|nsubjpass|phosphorylation reduced|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 hormone|nsubj|start_entity hormone|acl:relcl|inhibits inhibits|dobj|release release|nmod|growth_hormone growth_hormone|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 3.000000 0 0.000000 0 1.000000 0 0.000000 0 chelators|compound|start_entity initiated|dobj|chelators chelators|ccomp|initiated chelators|dobj|expression expression|nmod|receptor receptor|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 transport|compound|start_entity activation|nmod|transport activation|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 start_entity|nsubj|levels levels|nmod|end_entity 1.000000 0 0.000000 0 13.000000 0 1.000000 0 5.000000 0 46.000000 0 0.000000 0 17.000000 0 19.000000 0 5.000000 0 pathways|compound|start_entity intervention|nmod|pathways intervention|dep|proteins proteins|acl|targeted targeted|nmod|end_entity 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 antagonist|compound|start_entity irbesartan|appos|antagonist adding|dobj|irbesartan benefit|acl|adding blockade|appos|benefit occurring|nmod|blockade angiotensin_ii|acl|occurring levels|nmod|angiotensin_ii owing|nmod|levels examined|dep|owing examined|advcl|optimal optimal|nsubj|therapy therapy|nmod|inhibitors inhibitors|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 antagonist|compound|start_entity antagonist|acl:relcl|promotes promotes|dobj|interaction interaction|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 action|nmod|start_entity stimulated|nmod|action stimulated|nsubjpass|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 pyrrolidine_dithiocarbamate|dep|start_entity inhibitors|amod|pyrrolidine_dithiocarbamate attenuated|nsubj|inhibitors attenuated|advcl|indicating indicating|ccomp|regulator regulator|nmod|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 release|amod|start_entity induced|dobj|release induced|nmod|pmns pmns|acl|primed primed|nmod|agents agents|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 secretion|compound|start_entity pathway|nmod|secretion pathway|nsubj|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity regulator|nmod|levels regulator|nsubj|proprotein_convertase_subtilisin_kexin_type_9 proprotein_convertase_subtilisin_kexin_type_9|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 elevated|nmod|start_entity elevated|nsubj|concentrations concentrations|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 levels|amod|start_entity remained|nsubj|levels 3|acl:relcl|remained decreased|dobj|3 decreased|nsubjpass|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effects|nmod|start_entity modulator|nmod|effects has|nmod|modulator has|nsubj|observation observation|nmod|action action|nmod|eralpha eralpha|nmod|activation activation|nmod|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 removal|nmod|start_entity catalyzes|dobj|removal glutamine_synthetase|acl:relcl|catalyzes activity|nmod|glutamine_synthetase enhance|dobj|activity enhance|advcl|poised poised|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 production|appos|start_entity zingiberaceae|nmod|production zingiberaceae|acl|exhibited exhibited|dobj|inhibition inhibition|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 co-treated|dep|start_entity inhibition|amod|co-treated inhibition|nmod|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 extraction|nmod|start_entity osteocalcin|dep|extraction =|dep|osteocalcin analyzed|parataxis|= analyzed|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 induced|nsubj|start_entity induced|nmod|production production|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 12.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 start_entity|amod|binding binding|nmod|surface surface|nmod|domain domain|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentration|compound|start_entity osmolality|dep|concentration results|dep|osmolality results|dep|hrs hrs|nmod|commencement commencement|nmod|infusion infusion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 start_entity|nsubj|retinoid_x_receptor retinoid_x_receptor|appos|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 adrenaline|amod|start_entity secretion|nmod|adrenaline suppressed|nsubjpass|secretion mice|acl:relcl|suppressed mice|amod|corticotropin-releasing_hormone corticotropin-releasing_hormone|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 delivery|amod|start_entity delivery|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 resistant|dep|start_entity resistant|dep|overexpressed overexpressed|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 remove|dobj|start_entity function|ccomp|remove function|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 1.000000 0 0.000000 0 doses|nmod|start_entity corrected|nmod|doses corrected|advcl|discontinued discontinued|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 formyltransferase|compound|start_entity genes|compound|formyltransferase genes|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 exposure|nmod|start_entity occurred|nmod|exposure occurred|nmod|fibroblasts fibroblasts|acl|transfected transfected|nmod|cdnas cdnas|acl|encoding encoding|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 administered|nsubjpass|start_entity increased|advcl|administered pregnancy|acl:relcl|increased day|nmod|pregnancy induced|nmod|day induced|dobj|increase increase|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 12.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 peroxidase|amod|start_entity d-amphetamine_sulphate|appos|peroxidase d-amphetamine_sulphate|appos|glutathione-s-transferase glutathione-s-transferase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 inhibitors|amod|start_entity inhibitors|dep|overexpress overexpress|dobj|end_entity 0.000000 0 0.000000 0 7.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 using|advcl|start_entity using|nmod|cd62 cd62|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 receptor|amod|start_entity receptor|compound|anaplastic_lymphoma_kinase anaplastic_lymphoma_kinase|appos|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 metabolism|amod|start_entity step|nmod|metabolism mediates|dobj|step mediates|nsubj|cyclooxygenase-2 cyclooxygenase-2|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 transported|nsubjpass|start_entity called|dep|transported called|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 2.000000 0 0.000000 0 cells|amod|start_entity involvement|nmod|cells suggest|dobj|involvement suggest|advcl|reducing reducing|dobj|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|nummod|start_entity determining|nmod|treatment valuable|advcl|determining valuable|nsubj|measurement measurement|nmod|expression expression|amod|dihydropyrimidine_dehydrogenase dihydropyrimidine_dehydrogenase|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 using|dobj|start_entity blocked|advcl|using blocked|nsubj|inhibition inhibition|nmod|end_entity 0.000000 0 2.000000 0 1.000000 0 1.000000 0 5.000000 0 5.000000 0 21.000000 0 0.000000 0 0.000000 0 0.000000 0 pretreatment|nmod|start_entity modified|nsubj|pretreatment modified|dobj|response response|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 synthesis|nmod|start_entity stimulate|dobj|synthesis inhibits|advcl|stimulate inhibits|dobj|synthesis synthesis|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 activated|nmod|start_entity produced|advcl|activated produced|nsubj|treatment treatment|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 bond|nmod|start_entity important|nsubj|bond important|nmod|folding folding|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 signalling|compound|start_entity amplify|dobj|signalling shown|ccomp|amplify co-expression|acl|shown restore|nsubj|co-expression restore|dobj|responsiveness responsiveness|nmod|promoter promoter|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 acting|advmod|start_entity acting|nmod|inhibitors inhibitors|nmod|acetylcholinesterase acetylcholinesterase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 synthesis|amod|start_entity modulates|dobj|synthesis cyclic_gmp|acl:relcl|modulates site|nmod|cyclic_gmp demonstrated|dobj|site demonstrated|nsubj|domain domain|nmod|cyclic_gmp cyclic_gmp|amod|bound bound|advmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 bound|nsubjpass|start_entity bound|nmod|site site|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 analogue|compound|start_entity secretin|dep|analogue secretion|appos|secretin secretion|acl:relcl|stimulated stimulated|nmod|pathways pathways|appos|carbachol carbachol|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 antagonist|compound|start_entity mk-801|appos|antagonist treated|nmod|mk-801 newborns|acl|treated brains|nmod|newborns decreased|nmod|brains decreased|nsubjpass|immunoreactivity immunoreactivity|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 altered|nsubj|start_entity altered|dobj|half-life half-life|nmod|mrna mrna|amod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 using|dobj|start_entity sampling|advcl|using end_entity|acl|sampling 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 rats|nmod|start_entity behavior|nmod|rats modulation|nmod|behavior effects|nsubj|modulation effects|nmod|8-oh-dpat 8-oh-dpat|dep|dpat dpat|appos|agonist agonist|nummod|end_entity 2.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 amplifies|amod|start_entity amplifies|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 start_entity|amod|phosphatase phosphatase|dep|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 3.000000 0 1.000000 0 6.000000 0 2.000000 0 0.000000 0 0.000000 0 derived|nmod|start_entity response|dep|derived response|nmod|cells cells|compound|end_entity 1.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 10.000000 0 0.000000 0 1.000000 0 0.000000 0 content|amod|start_entity measured|nmod|content measured|nsubjpass|peroxidase peroxidase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 e.g.|dep|start_entity messengers|appos|e.g. messengers|acl:relcl|modulate modulate|dobj|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 anti-her-2|compound|start_entity combining|dobj|anti-her-2 breast_tumor|dep|combining breast_tumor|parataxis|oligodeoxynucleotides oligodeoxynucleotides|xcomp|treat treat|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 oocytes|nmod|start_entity treatment|nmod|oocytes decreased|nsubj|treatment decreased|dobj|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 8.000000 0 18.000000 0 2.000000 0 2.000000 0 1.000000 0 statins|appos|start_entity effects|nmod|statins determine|dobj|effects determine|nmod|regard regard|nmod|secretion secretion|nmod|interleukin-6 interleukin-6|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 estradiol|amod|start_entity steroids|dep|estradiol steroids|appos|tumor_necrosis_factor-alpha tumor_necrosis_factor-alpha|dep|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 symporter|compound|start_entity characterization|nmod|symporter reported|nsubjpass|characterization reported|parataxis|remained remained|nsubj|patterns patterns|nmod|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 2.000000 0 treatment|nmod|start_entity reduces|nsubj|treatment reduces|dobj|ligand ligand|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 glut1|compound|start_entity induction|nmod|glut1 studying|dobj|induction obtained|advcl|studying obtained|nmod|role role|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 inhibitor|amod|start_entity block|nsubj|inhibitor block|dobj|activation activation|nmod|end_entity 0.000000 0 0.000000 0 7.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 start_entity|appos|antagonist antagonist|nmod|transient_receptor_potential_cation_channel_subfamily_v_member_1 transient_receptor_potential_cation_channel_subfamily_v_member_1|appos|end_entity 0.000000 0 3.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nsubj|efficacy efficacy|nmod|antagonist antagonist|compound|end_entity 0.000000 0 2.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|dep|didecanoate didecanoate|appos|activator activator|dep|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 domperidone|appos|start_entity response|dep|domperidone response|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 assessed|nmod|start_entity function|dep|assessed function|amod|end_entity 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 aminotransferase|compound|start_entity aminotransferase|nmod|triglycerides triglycerides|nmod|levels levels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 insult|compound|start_entity reduced|nmod|insult reduced|nsubjpass|levels levels|nmod|com com|compound|end_entity 0.000000 0 0.000000 0 12.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 absorption|compound|start_entity involved|nmod|absorption involved|nsubjpass|calcium_sensing_receptor calcium_sensing_receptor|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nsubj|actions actions|nmod|benazepril_hydrochloride benazepril_hydrochloride|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 10.000000 0 0.000000 0 2.000000 0 0.000000 0 normalize|nmod|start_entity normalize|nsubj|administration administration|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 17.000000 0 0.000000 0 uptake|nmod|start_entity mediated|nsubjpass|uptake mediated|nmod|glucose_transporter-1 glucose_transporter-1|appos|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 23.000000 0 2.000000 0 1.000000 0 rad3|compound|start_entity has|nmod|rad3 has|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 inhibit|nsubj|start_entity inhibit|dep|signaling signaling|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 domain|amod|start_entity active|nsubj|domain indicating|ccomp|active autophosphorylated|xcomp|indicating autophosphorylated|nmod|stimulation stimulation|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 induced|nmod|start_entity induced|xcomp|lacking lacking|dobj|protein protein|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity causes|nsubj|treatment causes|nmod|affinity affinity|nmod|upar upar|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 washout|nmod|start_entity disappeared|dobj|washout disappeared|advcl|caused caused|dobj|accumulation accumulation|nmod|complex complex|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 12.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|nmod|start_entity studied|nmod|treatment studied|nsubjpass|patients patients|nmod|cardiac_and_oncologic_disease cardiac_and_oncologic_disease|acl:relcl|receiving receiving|ccomp|adjuvant adjuvant|xcomp|trastuzumab trastuzumab|dep|- -|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibits|advmod|start_entity inhibits|dobj|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 converts|nmod|start_entity converts|nsubj|enzyme enzyme|amod|11beta-hydroxysteroid_dehydrogenase_type_1 11beta-hydroxysteroid_dehydrogenase_type_1|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 vs|amod|start_entity =|dep|vs nights|dep|= continued|nmod|nights observed|advcl|continued elicit|advcl|observed elicit|dobj|increase increase|nmod|concentrations concentrations|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 valspodar|appos|start_entity using|dobj|valspodar inhibition|acl|using inhibition|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nmod|topotecin topotecin|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 availability|nummod|start_entity decreased|nsubj|availability attenuated|advcl|decreased was|parataxis|attenuated was|ccomp|release release|advcl|autoreceptors autoreceptors|nsubj|consequence consequence|nmod|end_entity 1.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 receptors|compound|start_entity build|dobj|receptors attempted|xcomp|build attempted|advcl|using using|dobj|structure structure|nmod|channel channel|compound|end_entity 0.000000 0 0.000000 0 14.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 liver|nmod|start_entity inhibition|nmod|liver inhibition|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 blocks|appos|start_entity end_entity|nsubj|blocks 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 dephosphorylation|amod|start_entity dephosphorylation|dep|part part|nmod|signaling signaling|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 mechanism|nmod|start_entity involved|nmod|mechanism involved|nsubjpass|end_entity 6.000000 0 0.000000 0 1.000000 0 2.000000 0 1.000000 0 11.000000 0 1.000000 0 1.000000 0 1.000000 0 0.000000 0 accumulation|compound|start_entity stimulates|dobj|accumulation stimulates|nsubj|- -|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 deficiency|amod|start_entity vitamin_d|appos|deficiency absence|nmod|vitamin_d found|nmod|absence found|nsubjpass|receptor receptor|appos|end_entity 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 3.000000 0 0.000000 0 6.000000 0 proteins|compound|start_entity known|nsubjpass|proteins known|nmod|ethylene ethylene|appos|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity reserved|nsubjpass|effects reserved|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 repair|amod|start_entity indispensable|nmod|repair encodes|dobj|indispensable encodes|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 set|nmod|start_entity chosen|nsubjpass|set chosen|nmod|basis basis|nmod|potential potential|acl|solvents solvents|nmod|processes processes|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 availability|compound|start_entity relevance|nmod|availability relevance|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 intake|compound|start_entity inhibit|dobj|intake inhibit|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 influx|nmod|start_entity receptor|nmod|influx mediated|nmod|receptor mediated|nsubjpass|synthesis synthesis|acl|elicited elicited|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 catabolism|amod|start_entity elevate|dobj|catabolism elevate|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 concentration|nmod|start_entity congruent|nsubjpass|concentration finding|dep|congruent together|nmod|finding encouraged|advmod|together encouraged|xcomp|conclude conclude|ccomp|inhibit inhibit|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 addition|nmod|start_entity diminished|nsubj|addition diminished|dobj|activity activity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 2.000000 0 7.000000 0 1.000000 0 1.000000 0 1.000000 0 depleted|nmod|start_entity depleted|nmod|absence absence|nmod|+ +|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 reported|nsubj|start_entity reported|advcl|elucidate elucidate|dobj|mechanism mechanism|acl:relcl|fsh fsh|nsubj|amplifies amplifies|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 concentration|compound|start_entity concentration|dep|association association|nmod|polymorphism polymorphism|nmod|gene gene|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 removes|dobj|start_entity glycosylase|acl:relcl|removes protein|appos|glycosylase protein|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 increases|amod|start_entity increases|nmod|level level|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 residues|amod|start_entity codes|nmod|residues codes|det|which sequence|ref|which reduced|nmod|sequence reduced|nsubjpass|interaction interaction|nmod|mab mab|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 tolerance|compound|start_entity improved|nsubj|tolerance studies|acl:relcl|improved stimulate|nmod|studies stimulate|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 17.000000 0 0.000000 0 subcutaneous|amod|start_entity pretreatment|nmod|subcutaneous pretreatment|appos|antagonists antagonists|compound|end_entity 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 concentration|compound|start_entity culture|nmod|concentration stimulates|nsubj|culture stimulates|dobj|production production|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|nsubj|characteristics characteristics|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 peptides|compound|start_entity together|nmod|peptides required|advmod|together required|ccomp|extended extended|nmod|discovery discovery|nmod|gene gene|acl:relcl|encodes encodes|dobj|tachykinins tachykinins|amod|end_entity 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|ref|which induce|nsubj|which induce|dobj|surge surge|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 phenotypes|amod|start_entity observed|nsubj|phenotypes observed|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nmod|presence presence|nmod|methionine_sulfoximine methionine_sulfoximine|appos|inhibitor inhibitor|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 produces|nsubj|start_entity produces|nmod|phosphatase phosphatase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 mobilization|compound|start_entity mobilization|acl|signaling signaling|dobj|pathways pathways|acl:relcl|importance importance|nmod|activation activation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 stable|nsubj|start_entity stable|nmod|aspart aspart|nmod|lispro lispro|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 maintenance|nmod|start_entity essential|nmod|maintenance essential|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 17-aag|appos|start_entity 17-aag|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 production|amod|start_entity suppressing|dobj|production histrelin|acl|suppressing histrelin|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 antagonist|appos|start_entity function|nmod|antagonist function|xcomp|indicating indicating|ccomp|is is|nsubj|function function|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 given|dobj|start_entity animals|acl|given slight|nmod|animals slight|nsubjpass|response response|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 portion|nmod|start_entity amino_acid|nmod|portion amino_acid|nsubj|receptor receptor|appos|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 that|nmod|start_entity had|nmod|that had|parataxis|ligand ligand|nsubj|end_entity 2.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 combination|nmod|start_entity leads|nsubj|combination leads|nmod|increase increase|nmod|levels levels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 expression|amod|start_entity explain|nmod|expression explain|parataxis|suggested suggested|xcomp|important important|nmod|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 responded|nmod|start_entity efficacy|acl:relcl|responded has|dobj|efficacy has|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 elicits|nsubj|start_entity elicits|dobj|phosphorylation phosphorylation|nmod|camp_response_element-binding_protein camp_response_element-binding_protein|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 deficiency|amod|start_entity causes|nsubj|deficiency causes|nmod|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 metabolism|compound|start_entity pathways|nmod|metabolism hgp|nmod|pathways regulator|nmod|hgp regulator|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 activity|amod|start_entity decrease|nmod|activity acquired|nmod|decrease acquired|dobj|ability ability|acl|deaminate deaminate|dobj|substances substances|acl:relcl|substrates substrates|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 resistance|compound|start_entity acquisition|nmod|resistance plays|nmod|acquisition plays|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 terminating|nmod|start_entity glycoconjugates|xcomp|terminating member|ccomp|glycoconjugates member|nmod|family family|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 resistance|compound|start_entity levels|nmod|resistance comparable|nsubj|levels confer|xcomp|comparable confer|nsubj|substitution substitution|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 concentration|amod|start_entity concentration|acl|displayed displayed|dobj|action action|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 9.000000 0 0.000000 0 0.000000 0 0.000000 0 cromakalim|advmod|start_entity received|nmod|cromakalim received|nmod|veins veins|nmod|coinfused coinfused|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 experiments|nmod|start_entity suggested|nsubj|experiments suggested|ccomp|require require|nsubj|induction induction|nmod|mrnas mrnas|nmod|heavy heavy|nmod|antigen antigen|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 n-glycosylase|amod|start_entity n-glycosylase|dep|variant variant|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 found|dobj|start_entity found|advcl|suggesting suggesting|dobj|involvement involvement|nmod|pathways pathways|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 11.000000 0 0.000000 0 0.000000 0 0.000000 0 hydroxylation|amod|start_entity involved|nmod|hydroxylation involved|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 start_entity|nmod|selectivity selectivity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 content|compound|start_entity reflection|nmod|content reflection|nsubj|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 producing|dobj|start_entity mediate|advcl|producing mediate|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 -4,5|amod|start_entity resulting|nsubj|-4,5 phosphorylate|dep|resulting phosphorylate|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 start_entity|appos|members members|nmod|family family|nmod|activators activators|compound|end_entity 3.000000 0 0.000000 0 2.000000 0 2.000000 0 0.000000 0 4.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 downregulated|nsubj|start_entity downregulated|dobj|expression expression|acl:relcl|suggests suggests|ccomp|main main|acl|signaling signaling|xcomp|responsible responsible|nmod|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nmod|estrogen_receptor-a estrogen_receptor-a|appos|end_entity 2.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 production|amod|start_entity neutrophil|parataxis|production neutrophil|dep|priming priming|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 effect|nmod|start_entity concerning|dobj|effect concerning|nmod|mechanism mechanism|acl:relcl|involves involves|dobj|activation activation|nmod|receptors receptors|nummod|end_entity 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 evoked|nsubj|start_entity evoked|dobj|release release|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 4.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 cells|nmod|start_entity exposure|nmod|cells modifies|nsubj|exposure modifies|dobj|expression expression|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 combination|nmod|start_entity suppresses|nsubj|combination suppresses|dobj|activation activation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 etc.|amod|start_entity etc.|amod|due due|nmod|use use|nmod|inhibitors inhibitors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 0.000000 0 consumption|compound|start_entity associations|nmod|consumption confer|dobj|associations confer|nsubj|promoter promoter|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 exhibited|nmod|start_entity exhibited|dobj|correlation correlation|nmod|expression expression|nmod|transporter transporter|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 tdi|dep|start_entity tdi|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 associates|compound|start_entity suggesting|dobj|associates revealed|xcomp|suggesting revealed|ccomp|correlated correlated|nmod|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|ref|which mediated|nsubjpass|which mediated|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|advcl|inducing inducing|dobj|accumulation accumulation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 release|amod|start_entity release|nmod|endothelin-1 endothelin-1|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 shares|nmod|start_entity shares|parataxis|binds binds|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 converted|nmod|start_entity converted|nmod|action action|nmod|decarboxylase decarboxylase|acl:relcl|exist exist|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 injection|compound|start_entity observed|nmod|injection observed|parataxis|modified modified|nsubjpass|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 peptidase|compound|start_entity end_entity|appos|peptidase 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 518|amod|start_entity phosphorylation|nmod|518 facilitating|dobj|phosphorylation facilitating|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 similar|xcomp|start_entity decreases|advcl|similar decreases|dobj|stability stability|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity compared|nsubjpass|effect compared|nmod|genotypes genotypes|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 2.000000 0 0.000000 0 3.000000 0 0.000000 0 change|nmod|start_entity change|dep|excretion excretion|acl:relcl|increased increased|nsubjpass|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 recovery|nmod|start_entity end_entity|dep|recovery 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 administration|amod|start_entity levels|nmod|administration similar|nmod|levels similar|nsubj|effect effect|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 species|compound|start_entity induced|xcomp|species transcription|dep|induced transcription|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 augmented|nmod|start_entity augmented|nsubjpass|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 m|amod|start_entity had|nsubj|m had|dobj|effect effect|acl|containing containing|advmod|directly directly|nmod|activity activity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 phosphorylated|nsubj|start_entity became|ccomp|phosphorylated became|nsubj|kinase kinase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 superior|compound|start_entity superior|nmod|nsclc nsclc|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 regenerate|dobj|start_entity absence|acl|regenerate glucocorticoids|nmod|absence glucocorticoids|nsubj|acts acts|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 block|nsubj|start_entity block|advcl|resulted resulted|nsubj|administration administration|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 therapy|amod|start_entity receptor|nmod|therapy receptor|nsubj|impact impact|nmod|smoking smoking|nmod|end_entity 0.000000 0 3.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 8.000000 0 0.000000 0 2.000000 0 0.000000 0 absorb|dobj|start_entity absorb|nsubj|subjects subjects|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 treatment|compound|start_entity cells|nmod|treatment decreased|advcl|cells decreased|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 homeostasis|compound|start_entity modulating|dobj|homeostasis plays|advcl|modulating plays|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 immobilize|dobj|start_entity using|advcl|immobilize characterized|xcomp|using characterized|nsubjpass|mechanism mechanism|nmod|inhibition inhibition|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 12-o-tetradecanoylphorbol-13-acetate|appos|start_entity critical|nmod|12-o-tetradecanoylphorbol-13-acetate critical|nsubj|elements elements|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity associated|nsubjpass|effects associated|nmod|activation activation|nmod|gene gene|appos|end_entity 6.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 gene|amod|start_entity coded|nmod|gene enzymes|acl|coded dna|nmod|enzymes dna|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 protein|dep|start_entity protein|appos|albumin albumin|appos|factor-i factor-i|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 atp|dep|start_entity effect|appos|atp effect|nmod|release release|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effect|nmod|start_entity influence|nmod|effect influence|nmod|polymorphism polymorphism|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 3.000000 0 0.000000 0 studied|nmod|start_entity studied|nmod|inactivation inactivation|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transporter|amod|start_entity expression|nmod|transporter alterations|nmod|expression end_entity|dep|alterations 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 channel|compound|start_entity defects|nmod|channel secondary|nmod|defects end_entity|amod|secondary 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 signaling|compound|start_entity insulin/igf|nmod|signaling insulin/igf|dep|force force|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 1.000000 0 0.000000 0 esterification|compound|start_entity rate|nmod|esterification rate|acl|assessed assessed|nmod|activity activity|appos|2.3.1.43 2.3.1.43|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 excretion|nmod|start_entity increased|dep|excretion increased|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 30.000000 0 0.000000 0 forming|amod|start_entity cyclizing|appos|forming mutase|dep|cyclizing -2,3|dep|mutase synthase|dobj|-2,3 synthase|ccomp|report report|dobj|cloning cloning|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 elaboration|nmod|start_entity lead|nmod|elaboration pathways|acl:relcl|lead opposing|dobj|pathways utilized|advcl|opposing produced|dep|utilized produced|nsubj|synthase synthase|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 5.000000 0 2.000000 0 10.000000 0 increases|nsubj|start_entity increases|xcomp|binding binding|nmod|element element|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 hydrolysis|compound|start_entity induced|nmod|hydrolysis change|acl|induced play|nmod|change propose|ccomp|play propose|advcl|examining examining|dobj|energetics energetics|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nmod|activate activate|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 mg/kg|nmod|start_entity treatment|nmod|mg/kg caused|nsubj|treatment caused|nmod|mice mice|acl|implanted implanted|nmod|mg mg|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 causes|amod|start_entity causes|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|amod|start_entity led|nsubj|treatment led|nmod|clones clones|acl|expressing expressing|dobj|rna rna|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 accumulation|compound|start_entity stages|nmod|accumulation transcriptome|nmod|stages associated|nmod|transcriptome associated|nmod|knockout knockout|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 1.000000 0 0.000000 0 actions|nmod|start_entity tested|nsubjpass|actions framework|acl:relcl|tested provide|dobj|framework provide|advcl|possible possible|xcomp|determine determine|nmod|neurons neurons|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 receptors|amod|start_entity mediated|nmod|receptors mediated|advcl|inhibited inhibited|nmod|pyrilamine pyrilamine|appos|antagonist antagonist|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transport|compound|start_entity transport|nmod|translocation translocation|nmod|end_entity 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 34.000000 0 10.000000 0 0.000000 0 known|nmod|start_entity known|nsubjpass|synthase synthase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 level|nmod|start_entity result|nmod|level dopamine_transporter|acl:relcl|result reduction|nmod|dopamine_transporter associated|nmod|reduction associated|nsubjpass|allele allele|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 exhibit|nmod|start_entity exhibit|nsubj|concentrations concentrations|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 9.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 moieties|amod|start_entity moieties|acl:relcl|bind bind|nmod|asialoglycoprotein_receptor asialoglycoprotein_receptor|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 reaction|amod|start_entity assess|dobj|reaction assess|advcl|evaluate evaluate|dobj|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 messenger|nsubj|start_entity messenger|acl:relcl|protein_kinase_a protein_kinase_a|appos|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|compound|start_entity showed|nmod|uptake showed|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 metabolism|compound|start_entity reporting|nmod|metabolism used|advcl|reporting used|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 17.000000 0 0.000000 0 sequence|amod|start_entity analysis|nmod|sequence reveals|nsubj|analysis reveals|dobj|iterations iterations|ref|that conserved|nsubj|that conserved|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 oxidase|compound|start_entity expressed|nmod|oxidase cells|acl|expressed using|dobj|cells investigated|xcomp|using investigated|nsubjpass|selectivity selectivity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 described|nmod|start_entity had|advcl|described had|dobj|activity activity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 7.000000 0 0.000000 0 1.000000 0 0.000000 0 hydrolysis|compound|start_entity stimulated|dobj|hydrolysis stimulated|nmod|complex complex|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 start_entity|appos|peptides peptides|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 antagonist|appos|start_entity antagonist|compound|effects effects|appos|end_entity 0.000000 0 3.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 infusion|amod|start_entity insulin|nmod|infusion hg|nmod|insulin mm|acl|hg +|dep|mm averaged|dobj|+ pressure|acl:relcl|averaged increase|dobj|pressure increase|nsubj|infusion infusion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 age|appos|start_entity end_entity|nsubj|age 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 target|compound|start_entity expressed|nmod|target end_entity|acl:relcl|expressed 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 14.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 effect|nmod|start_entity mimicked|dobj|effect mimicked|nsubj|dihydroxyphenylglycine dihydroxyphenylglycine|appos|agonist agonist|amod|end_entity 0.000000 0 0.000000 0 10.000000 0 2.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 infusion|compound|start_entity period|nmod|infusion infusion|nmod|period caused|nsubj|infusion caused|xcomp|similar similar|nsubj|release release|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 movement|acl|start_entity part|nmod|movement mediates|nmod|part mediates|nsubj|isoform isoform|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 15.000000 0 0.000000 0 1.000000 0 dismutase|amod|start_entity exception|nmod|dismutase higher|nmod|exception higher|nsubj|activities activities|nmod|peroxidase peroxidase|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 release|appos|start_entity release|acl|induced induced|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 t3|dep|start_entity rise|nmod|t3 prevented|nsubjpass|rise fetuses|acl:relcl|prevented abolished|nmod|fetuses abolished|nsubjpass|decline decline|nmod|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 production|amod|start_entity production|dep|competition competition|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 5.000000 0 1.000000 0 7.000000 0 antagonist|appos|start_entity used|nsubjpass|antagonist study|acl:relcl|used performed|dobj|study performed|advcl|ascertain ascertain|ccomp|mediated mediated|nmod|reduction reduction|nmod|formation formation|appos|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity occur|nsubj|effects suggesting|ccomp|occur estimated|xcomp|suggesting estimated|dobj|half-life half-life|nmod|mrna mrna|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 monotherapy|compound|start_entity approach|nsubj|monotherapy approach|advcl|lower lower|xcomp|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 treatment|nmod|start_entity resulted|nsubj|treatment resulted|nmod|sam-dc sam-dc|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 relationship|acl|start_entity stimulation|dep|relationship stimulation|amod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 attenuated|dep|start_entity activation|amod|attenuated inhibitors|dobj|activation inhibitors|nsubj|treatment treatment|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 transfer|nmod|start_entity maintain|nmod|transfer maintain|nmod|reaction reaction|amod|end_entity 1.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effects|nmod|start_entity due|nsubj|effects due|nmod|change change|nmod|level level|nmod|ob-ra ob-ra|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 complex|compound|start_entity assembly|nmod|complex blocking|dobj|assembly inhibiting|dep|blocking inhibiting|dobj|phosphorylation phosphorylation|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 species|compound|start_entity event|nsubj|species event|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 insulin|nmod|start_entity effect|nmod|insulin effect|acl|handling handling|nmod|resistance resistance|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 insensitivity|compound|start_entity presence|nmod|insensitivity investigate|dobj|presence measured|advcl|investigate measured|nsubjpass|androgen_receptor androgen_receptor|appos|end_entity 1.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 glucose-carbon|nmod|start_entity intermediates|amod|glucose-carbon flux|nmod|intermediates reduced|nsubjpass|flux reduced|nmod|incubations incubations|nmod|cells cells|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 ligands|nmod|start_entity variety|nmod|ligands activated|nmod|variety activated|nsubjpass|receptors receptors|appos|end_entity 1.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|compound|start_entity role|nmod|metabolism focused|nmod|role focused|advcl|established established|nsubjpass|importance importance|nmod|apolipoprotein_e apolipoprotein_e|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 response|nmod|start_entity release|nmod|response have|dobj|release have|nsubj|islets islets|acl|exposed exposed|nmod|il-1_beta il-1_beta|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 concentration|compound|start_entity concentration|nmod|medium medium|dep|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 18.000000 0 0.000000 0 inhibited|nsubj|start_entity tlr8|acl:relcl|inhibited expressing|dobj|tlr8 examined|advcl|expressing examined|nsubjpass|signalling signalling|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 inhibitors|amod|start_entity affinities|nmod|inhibitors investigate|dobj|affinities investigate|nmod|end_entity 0.000000 0 0.000000 0 7.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 protein|compound|start_entity redistribution|nmod|protein executed|nmod|redistribution executed|nmod|form form|acl:relcl|involves involves|dobj|modulation modulation|acl:relcl|govern govern|dobj|trafficking trafficking|nmod|proteins proteins|nmod|transduction transduction|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 start_entity|appos|potentiator potentiator|nmod|probability probability|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 doses|compound|start_entity enhanced|nmod|doses appear|xcomp|enhanced ablated|advcl|appear ablated|xcomp|showing showing|ccomp|sensitive sensitive|advmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 attempted|nmod|start_entity patients|acl:relcl|attempted obtained|nmod|patients end_entity|dep|obtained 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 activity|nummod|start_entity regulated|nsubjpass|activity regulated|nmod|autoreceptors autoreceptors|nummod|end_entity 1.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|appos|inhibitor inhibitor|nmod|cytosolic_phospholipase_a2 cytosolic_phospholipase_a2|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 hydroxylation|nmod|start_entity measuring|dobj|hydroxylation assayed|advcl|measuring assayed|nsubjpass|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 limiting|nsubj|start_entity environment|acl:relcl|limiting adapting|nmod|environment assist|advcl|adapting expression|acl:relcl|assist induces|dobj|expression induces|nsubj|activation activation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 breakdown|nmod|start_entity prevent|dobj|breakdown attempt|xcomp|prevent inhibitors|acl:relcl|attempt classified|nsubjpass|inhibitors classified|dobj|acting acting|acl|acting acting|advcl|time time|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 block|nsubj|start_entity block|dobj|inhibition inhibition|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 blunted|nmod|start_entity blunted|nsubjpass|response response|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 0.000000 0 14.000000 0 0.000000 0 observed|nmod|start_entity observed|ccomp|smaller smaller|xcomp|suggesting suggesting|nmod|absence absence|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 administration|compound|start_entity reinstituted|nsubjpass|administration synthesize|advcl|reinstituted synthesize|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 resulted|nmod|start_entity resulted|nsubj|stimulation stimulation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 catabolism|compound|start_entity pathway|nmod|catabolism dioxygenase|amod|pathway dioxygenase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 evaluation|nmod|start_entity supporting|dobj|evaluation osteolysis|acl|supporting osteolysis|amod|functional functional|dep|sequelae sequelae|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 release|compound|start_entity enhancement|nmod|release mediated|nmod|enhancement mediated|nsubjpass|action action|nmod|glucocorticoids glucocorticoids|nmod|response response|acl|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 levels|amod|start_entity free|dobj|levels free|nsubj|patterns patterns|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 cells|compound|start_entity measured|advcl|cells measured|nmod|cells cells|appos|-1 -1|amod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 investigate|nmod|start_entity investigate|dobj|mechanism mechanism|nmod|activation activation|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 abrogated|nmod|start_entity abrogated|xcomp|suggesting suggesting|ccomp|essential essential|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 epidermal_growth_factor_receptor|amod|start_entity epidermal_growth_factor_receptor|appos|end_entity 0.000000 0 16.000000 0 63.000000 0 23.000000 0 106.000000 0 101.000000 0 208.000000 0 21.000000 0 22.000000 0 9.000000 0 matrix|compound|start_entity matrix|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 6.000000 0 0.000000 0 down-modulation|nmod|start_entity down-modulation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transporter|compound|start_entity viewed|nmod|transporter viewed|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 exposure|compound|start_entity diminishes|nmod|exposure diminishes|dobj|transcription transcription|amod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 provocation|amod|start_entity reduced|nmod|provocation reduced|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 clearance|amod|start_entity ratio|nmod|clearance ratio|nmod|probe probe|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 estradiol|amod|start_entity stimulated|dobj|estradiol increase|dep|stimulated increase|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 species|compound|start_entity release|nmod|species associated|nmod|release injury|acl:relcl|associated role|nmod|injury plays|dobj|role plays|nsubj|tumor_necrosis_factor-alpha tumor_necrosis_factor-alpha|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 start_entity|appos|sugar sugar|acl:relcl|inhibits inhibits|xcomp|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 increase|nmod|start_entity increase|nsubj|levels levels|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 30.000000 0 0.000000 0 4.000000 0 24.000000 0 1.000000 0 discharge|compound|start_entity allow|dobj|discharge allow|nmod|cells cells|nmod|accord accord|nmod|modification modification|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 structure|compound|start_entity have|dobj|structure postulated|advcl|have postulated|ccomp|preceded preceded|nmod|complex complex|compound|end_entity 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 that|nmod|start_entity different|nmod|that mechanism|amod|different facilitates|nmod|mechanism facilitates|nsubj|mkc-242 mkc-242|appos|agonist agonist|nummod|end_entity 2.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 exerted|nsubj|start_entity mechanism|acl:relcl|exerted differed|nsubj|mechanism differed|nmod|that that|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 manipulation|amod|start_entity effect|nmod|manipulation investigated|dobj|effect investigated|nmod|difference difference|nmod|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pretreatment|amod|start_entity increased|nsubj|pretreatment increased|iobj|activation activation|amod|content content|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 outcome|amod|start_entity predicts|dobj|outcome predicts|nsubj|polymorphism polymorphism|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 11.000000 0 0.000000 0 1.000000 0 0.000000 0 responsive|nmod|start_entity responsive|nsubj|end_entity 3.000000 0 1.000000 0 11.000000 0 7.000000 0 0.000000 0 17.000000 0 2.000000 0 5.000000 0 3.000000 0 0.000000 0 transport|compound|start_entity depends|nsubj|transport depends|nmod|vitamin_d3 vitamin_d3|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 using|dobj|start_entity selected|xcomp|using selected|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 differentiation|nmod|start_entity differentiation|dep|synthesis synthesis|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 molecule-1|amod|start_entity molecule-1|amod|synthase synthase|dep|end_entity 0.000000 0 0.000000 0 1.000000 0 3.000000 0 1.000000 0 8.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 inhibit|nsubj|start_entity inhibit|dobj|activation activation|nmod|tumor_necrosis_factor-alpha tumor_necrosis_factor-alpha|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 species|compound|start_entity detoxicate|dobj|species activities|acl:relcl|detoxicate activities|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 treatment|compound|start_entity reduced|nsubj|treatment reduced|ccomp|reflected reflected|nsubjpass|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 decreased|nsubj|start_entity decreased|dobj|increase increase|nmod|mrna mrna|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibits|nsubj|start_entity 8|acl:relcl|inhibits sustained|nmod|8 min|acl:relcl|sustained caused|nmod|min caused|dobj|accumulation accumulation|nmod|mrna mrna|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 diet|compound|start_entity fed|nmod|diet rabbits|acl|fed concentration|nmod|rabbits concentration|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 uptake|compound|start_entity influenced|nsubjpass|uptake influenced|nmod|intestine intestine|nmod|affinity affinity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 13.000000 0 2.000000 0 0.000000 0 formation|compound|start_entity observed|nsubj|formation observed|advcl|expressing expressing|dobj|g g|amod|acquired acquired|dep|mutant mutant|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 inhibitors|appos|start_entity have|nsubj|inhibitors reduced|advcl|have reduced|nsubj|sb202190 sb202190|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|appos|drug drug|acl:relcl|blocks blocks|xcomp|forcing forcing|xcomp|release release|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 treatment|nmod|start_entity resulted|nsubj|treatment resulted|nmod|phosphorylation phosphorylation|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 lower|dobj|start_entity lower|nmod|increase increase|nmod|utilization utilization|nmod|elevation elevation|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 administration|amod|start_entity resulted|nsubj|administration resulted|nmod|immunocoprecipitation immunocoprecipitation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 l|dep|start_entity spectrophotometrically|nsubj|l inhibited|advcl|spectrophotometrically inhibited|dobj|activities activities|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transports|dobj|start_entity protein|acl:relcl|transports encoding|dobj|protein gene|acl|encoding gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 2.000000 0 0.000000 0 response|compound|start_entity contributes|nmod|response contributes|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 conversion|nmod|start_entity catalyzes|nmod|conversion enzyme|acl:relcl|catalyzes end_entity|appos|enzyme 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptor|compound|start_entity suppression|nmod|receptor resulted|nsubj|suppression resulted|nmod|upregulation upregulation|nmod|expression expression|amod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transport|compound|start_entity mutations|nmod|transport mutations|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 3.000000 0 5.000000 0 0.000000 0 2-amino-4-phosphonobutyrate|appos|start_entity is|nsubj|2-amino-4-phosphonobutyrate is|dep|agonist agonist|acl:relcl|acts acts|nmod|receptors receptors|appos|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 repair|compound|start_entity involved|nmod|repair protein|acl|involved identified|nmod|protein identified|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 sequestration|compound|start_entity promoting|dobj|sequestration detrimental|advcl|promoting detrimental|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 11.000000 0 0.000000 0 4.000000 0 12.000000 0 1.000000 0 approach|nsubj|start_entity approach|nmod|deficiency deficiency|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 ix|compound|start_entity ix|appos|inhibitor inhibitor|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 6.000000 0 0.000000 0 1.000000 0 0.000000 0 capacity|compound|start_entity increase|nmod|capacity induces|nmod|increase induces|dobj|increase increase|nmod|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 17.000000 0 5.000000 0 0.000000 0 constriction|compound|start_entity influence|dobj|constriction influence|nsubj|denervation denervation|acl:relcl|contain contain|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 acting|advcl|start_entity acting|nmod|inhibitors inhibitors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 <|compound|start_entity <|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 19.000000 0 0.000000 0 measured|nsubjpass|start_entity exogenous|acl:relcl|measured containing|dobj|exogenous added|xcomp|containing treated|advcl|added treated|nmod|experiments experiments|acl|designed designed|xcomp|measure measure|dobj|activity activity|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 start_entity|nmod|mechanism mechanism|acl:relcl|involved involved|nmod|transcription transcription|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 levels|nmod|start_entity changes|nmod|levels predictor|nsubj|changes predictor|nmod|inhibition inhibition|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 phorbol_myristate_acetate|appos|start_entity cells|nmod|phorbol_myristate_acetate pretreatment|nmod|cells blocked|nsubj|pretreatment blocked|dobj|stimulation stimulation|nmod|release release|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 using|dobj|start_entity signaling|advcl|using therapy|acl|signaling therapy|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 4.000000 0 0.000000 0 1.000000 0 0.000000 0 odt|compound|start_entity odt|appos|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 ache|amod|start_entity universal|nmod|ache considered|dobj|universal considered|nsubjpass|none none|nmod|reactivators reactivators|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 indicators|compound|start_entity offer|nsubj|indicators offer|advcl|permeable permeable|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity allows|nsubj|treatment allows|advcl|inhibiting inhibiting|dobj|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitor|nsubj|start_entity anticipated|ccomp|inhibitor exhibits|csubj|anticipated exhibits|dobj|selectivity selectivity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity blocked|nsubjpass|effect blocked|nmod|nan_190 nan_190|amod|end_entity 2.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity cells|nmod|treatment end_entity|nmod|cells 3.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 3.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 secretion|compound|start_entity kinase|nmod|secretion kinase|nmod|effect effect|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 dose|nmod|start_entity given|dobj|dose group|acl|given had|nsubj|group had|dobj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 concentrations|compound|start_entity differ|nsubj|concentrations differ|dobj|statistically statistically|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 cadpr|amod|start_entity concentrations|nmod|cadpr ruthenium_red|appos|concentrations ruthenium_red|compound|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 3.000000 0 0.000000 0 1.000000 0 effect|nmod|start_entity effect|acl:relcl|enhanced enhanced|nmod|presence presence|nmod|antagonists antagonists|amod|mineralocorticoid_receptor mineralocorticoid_receptor|dep|end_entity 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 phosphatase|appos|start_entity measured|nsubjpass|phosphatase measured|nmod|levels levels|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 accelerate|advmod|start_entity accelerate|nsubj|mu_opioid_receptor mu_opioid_receptor|appos|end_entity 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 src|amod|start_entity expression|nmod|src induced|dobj|expression beta-escin|acl|induced phosphatase|nsubj|beta-escin phosphatase|dobj|1 1|acl:relcl|correlated correlated|nmod|down-regulation down-regulation|nmod|activation activation|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 prevented|nmod|start_entity frequency|acl:relcl|prevented decreased|dobj|frequency decreased|advcl|indicating indicating|ccomp|inhibits inhibits|nsubj|activation activation|nmod|end_entity 3.000000 0 2.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 homeostasis|compound|start_entity link|nmod|homeostasis end_entity|dep|link 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 3.000000 0 5.000000 0 0.000000 0 secretion|appos|start_entity regulator|nmod|secretion regulator|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 functions|nmod|start_entity sectosteroid|dep|functions receptor|amod|sectosteroid receptor|appos|end_entity 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 3.000000 0 0.000000 0 6.000000 0 inhibitors|nmod|start_entity end_entity|nmod|inhibitors 0.000000 0 4.000000 0 1.000000 0 1.000000 0 23.000000 0 26.000000 0 56.000000 0 2.000000 0 13.000000 0 1.000000 0 changing|nsubj|start_entity appear|advcl|changing appear|nsubj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 18.000000 0 0.000000 0 secretion|amod|start_entity that|nmod|secretion less|nmod|that less|nsubj|sensitivity sensitivity|nmod|release release|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 maintained|nsubjpass|start_entity normalized|advcl|maintained normalized|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 18.000000 0 0.000000 0 androgen_5alpha-dihydrotestosterone|appos|start_entity rate|nmod|androgen_5alpha-dihydrotestosterone translocating|nmod|rate translocating|dobj|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 glucocorticoid|appos|start_entity sequences|nmod|glucocorticoid indicated|dobj|sequences indicated|nsubj|region region|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthases|amod|start_entity activity|nmod|synthases activity|nmod|expression expression|nmod|isoform isoform|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 5.000000 0 1.000000 0 7.000000 0 relationship|nmod|start_entity investigate|dobj|relationship glucoronosyltransferase|csubj|investigate glucoronosyltransferase|dobj|1a1 1a1|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 receptors|compound|start_entity receptors|dep|er er|dep|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 metabolism|compound|start_entity modulation|nmod|metabolism functions|nmod|modulation has|dobj|functions has|nsubj|erythropoietin erythropoietin|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 relaxations|appos|start_entity relaxations|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 reduced|dep|start_entity reduced|dobj|mrna mrna|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 rates|compound|start_entity increase|dobj|rates increase|nsubj|product product|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 higher|advcl|start_entity higher|nsubj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 presence|nmod|start_entity examined|nmod|presence examined|nsubjpass|changes changes|nmod|protein protein|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 combination|amod|start_entity analyses|nmod|combination analyses|dobj|relationship relationship|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 generation|compound|start_entity increased|dobj|generation increased|nsubj|dose-dependently dose-dependently|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 assess|nmod|start_entity assess|dobj|effect effect|nmod|antagonist antagonist|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 enantiomer|nmod|start_entity r-citalopram|appos|enantiomer modulator|nsubj|r-citalopram modulator|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 axis|amod|start_entity end_entity|dep|axis 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 composed|nmod|start_entity predicted|xcomp|composed predicted|advcl|281 281|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 agonist|compound|start_entity agonist|appos|blocker blocker|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 vitamin_d3_receptor|amod|start_entity form|nmod|vitamin_d3_receptor role|nmod|form summarizes|nmod|role summarizes|advmod|as as|advcl|describes describes|dobj|influence influence|nmod|polymorphisms polymorphisms|nmod|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 release|amod|start_entity increase|nmod|release activation|nmod|increase activation|amod|end_entity 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 radicals|compound|start_entity presence|nmod|radicals resulted|nsubj|presence resulted|nmod|release release|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity attenuates|dobj|effects attenuates|nsubj|administration administration|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 response|nmod|start_entity suggesting|ccomp|response affected|advcl|suggesting affected|dobj|mrna mrna|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 3.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|xcomp|stimulate stimulate|dobj|activity activity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 pretreatment|compound|start_entity due|nmod|pretreatment phosphorylation|amod|due phosphorylation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibits|nmod|start_entity becomes|parataxis|inhibits becomes|csubj|contain contain|dobj|receptors receptors|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 load|compound|start_entity diet|nmod|load investigated|nmod|diet investigated|nsubjpass|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 subunits|advcl|start_entity oxidase|amod|subunits oxidase|amod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 contribute|nmod|start_entity raising|ccomp|contribute reduced|xcomp|raising reduced|nsubjpass|levels levels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 proteins|amod|start_entity based|nmod|proteins extent|acl|based extent|advcl|is is|nsubj|structure structure|nmod|end_entity 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 3.000000 0 effect|nmod|start_entity involved|nmod|effect involved|nsubjpass|end_entity 3.000000 0 0.000000 0 7.000000 0 3.000000 0 2.000000 0 19.000000 0 1.000000 0 0.000000 0 6.000000 0 0.000000 0 effects|nmod|start_entity expressed|nsubj|effects expressed|ccomp|analyzed analyzed|nsubjpass|channels channels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 changes|nmod|start_entity associated|nsubjpass|changes associated|nmod|change change|nmod|sensitivity sensitivity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 absence|nmod|start_entity bind|nmod|absence bind|nmod|dna dna|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 14.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 load|compound|start_entity suppressed|nmod|load concentrations|acl:relcl|suppressed concentrations|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 transfer|nmod|start_entity based|nmod|transfer based|nmod|modeling modeling|nmod|interaction interaction|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 start_entity|dep|antagonist antagonist|nmod|end_entity 3.000000 0 41.000000 0 3.000000 0 0.000000 0 9.000000 0 9.000000 0 50.000000 0 0.000000 0 2.000000 0 0.000000 0 up-regulated|nmod|start_entity up-regulated|nsubj|gene gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 kinases|compound|start_entity tyrosine|nmod|kinases phosphorylation|nmod|tyrosine responsible|nmod|phosphorylation responsible|nsubj|kinase kinase|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 influx|compound|start_entity mediate|nsubj|influx mediate|dobj|formation formation|nmod|complex complex|acl|involving involving|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 serine|compound|start_entity phosphorylation|nmod|serine promotes|dobj|phosphorylation promotes|nsubj|end_entity 0.000000 0 0.000000 0 3.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 reconstitution|compound|start_entity order|nsubj|reconstitution order|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthase|amod|start_entity cyclooxygenase-2|appos|synthase cyclooxygenase-2|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 9.000000 0 0.000000 0 5.000000 0 2.000000 0 13.000000 0 sensitive|nmod|start_entity found|parataxis|sensitive found|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 concentration|compound|start_entity elevated|nsubj|concentration increase|acl:relcl|elevated accompanied|nsubjpass|increase accompanied|nmod|activation activation|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 treated|nmod|start_entity nha|acl|treated showed|nsubj|nha showed|advcl|upregulating upregulating|advmod|as as|nmod:npmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 period|amod|start_entity /|nmod|period /|nsubj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 start_entity|ccomp|shown shown|ccomp|act act|nmod|receptor receptor|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 activation|nmod|start_entity groups|dep|activation groups|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 -rsb-|nsubj|start_entity -rsb-|dobj|levels levels|acl|led led|nmod|repressor repressor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 sequence|amod|start_entity shows|nsubj|sequence shows|advcl|sequence sequence|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 catabolites|compound|start_entity engage|nsubj|catabolites engage|dobj|reactivity reactivity|compound|end_entity 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 tolerances|compound|start_entity tolerances|advcl|borderline borderline|nsubj|and/or and/or|dep|values values|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 effects|nmod|start_entity control|dobj|effects control|nmod|levels levels|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 concentration|compound|start_entity increased|nsubj|concentration increased|nmod|capsaicin capsaicin|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 start_entity|appos|blocker blocker|acl:relcl|inhibits inhibits|xcomp|signaling signaling|nmod|homodimers homodimers|acl|formed formed|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 obtain|dobj|start_entity obtain|nmod|compounds compounds|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 metabolism|nmod|start_entity step|nmod|metabolism catalyses|dobj|step catalyses|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 balance|amod|start_entity shifted|nsubj|balance shifted|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 metabolism|amod|start_entity resistance|dep|metabolism resistance|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 compounds|nmod|start_entity effects|nmod|compounds effects|dep|androgen_receptor androgen_receptor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity increased|dobj|levels increased|parataxis|dependent dependent|nsubj|blockade blockade|nmod|activation activation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|dobj|transport transport|nmod|presence presence|nmod|parathyroid_hormone parathyroid_hormone|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 8.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 synthase|nsubj|start_entity increased|ccomp|synthase increased|nsubj|inhibitors inhibitors|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 proteins|compound|start_entity family|nmod|proteins involved|nsubjpass|family fact|dep|involved basis|nmod|fact undertaken|nmod|basis undertaken|nmod|focus focus|nmod|localization localization|nmod|structures structures|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 test|compound|start_entity used|nsubjpass|test provide|advcl|used provide|dobj|measure measure|nmod|responsiveness responsiveness|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 study|compound|start_entity trials|appos|study shown|nsubj|trials shown|ccomp|reduce reduce|nmod|patients patients|nmod|heart_failure heart_failure|nmod|top top|nmod|inhibition inhibition|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 agents|compound|start_entity impact|nmod|agents resistance|dep|impact resistance|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 uptake|nmod|start_entity responsible|nmod|uptake transporter|acl:relcl|responsible transporter|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 uptake|compound|start_entity effects|nmod|uptake effects|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 2.000000 0 0.000000 0 67.000000 0 0.000000 0 6.000000 0 150.000000 0 0.000000 0 receptor-coactivators|amod|start_entity receptor-coactivators|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 epitope|compound|start_entity identified|nmod|epitope identified|nmod|antibodies antibodies|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 uptake|nsubj|start_entity uptake|nmod|cell cell|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 reduction|nmod|start_entity inhibited|nsubjpass|reduction inhibited|nmod|receptor receptor|acl:relcl|bind bind|advmod|other other|nmod|site site|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 affecting|dobj|start_entity control|advcl|affecting end_entity|xcomp|control 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 co-infusion|nmod|start_entity prevents|nsubj|co-infusion mediated|advcl|prevents mediated|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 clearance|compound|start_entity transport|dep|clearance transport|dep|lipoprotein lipoprotein|dep|endosomes endosomes|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 transport|amod|start_entity nature|nmod|transport explain|dobj|nature explain|nmod|kinetics kinetics|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 potently|amod|start_entity promotes|nsubj|potently involve|advcl|promotes involve|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 199|acl|start_entity protein|nmod|199 protein|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 toxic|nsubj|start_entity lies|advcl|toxic lies|nsubj|importance importance|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 dysfunction|amod|start_entity inhibits|nsubj|dysfunction inhibits|dobj|activity activity|amod|end_entity 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 triggers|nsubj|start_entity triggers|advcl|leading leading|nmod|up-regulation up-regulation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 cilostazol|compound|start_entity therapy|appos|cilostazol comparison|nmod|therapy comparison|acl|using using|dobj|assay assay|nummod|end_entity 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 demonstrate|nmod|start_entity document|advcl|demonstrate document|dobj|interactions interactions|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|amod|glutathione_s-transferase glutathione_s-transferase|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 cysteine|appos|start_entity investigated|nmod|cysteine investigated|dobj|forms forms|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 stain|dobj|start_entity ferrocyanide|xcomp|stain used|xcomp|ferrocyanide used|advcl|evaluate evaluate|dobj|distribution distribution|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 residues|amod|start_entity deleting|dobj|residues created|advcl|deleting created|nsubjpass|mutant mutant|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 caused|xcomp|start_entity caused|nmod|deficiency deficiency|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 interaction|nmod|start_entity unrelated|nsubj|interaction unrelated|nmod|antagonism antagonism|amod|end_entity 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 consumption|compound|start_entity patients|nmod|consumption levels|nmod|patients levels|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 aggravates|dobj|start_entity aggravates|nsubj|end_entity 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 withdrawal|compound|start_entity exposure|nmod|withdrawal formation|nmod|exposure formation|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 tert-butylhydroquinone|appos|start_entity display|dobj|tert-butylhydroquinone activity|dep|display exhibit|dobj|activity exhibit|parataxis|activity activity|amod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 upregulation|compound|start_entity exposure|nmod|upregulation exposure|acl|leading leading|xcomp|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 start_entity|compound|kinase kinase|appos|end_entity 0.000000 0 3.000000 0 0.000000 0 1.000000 0 6.000000 0 3.000000 0 41.000000 0 0.000000 0 1.000000 0 0.000000 0 presence|nmod|start_entity produced|nmod|presence phosphatidylbutanol|acl:relcl|produced analyzed|dobj|phosphatidylbutanol analyzed|advcl|produced produced|nmod|enzymes enzymes|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 status|compound|start_entity measure|nmod|status percentage|appos|measure percentage|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 induce|nsubj|start_entity elicited|parataxis|induce elicited|dobj|response response|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 able|nsubj|start_entity appears|advcl|able appears|xcomp|potentiate potentiate|dobj|induction induction|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 7.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 inhibited|nsubj|start_entity inhibited|nmod|order order|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 concentration|amod|start_entity effect|nmod|concentration had|dobj|effect stimulate|advcl|had stimulate|dobj|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 15.000000 0 0.000000 0 0.000000 0 14.000000 0 0.000000 0 availability|compound|start_entity changes|nmod|availability changes|nmod|differentiation differentiation|nmod|expression expression|amod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 site|nmod|start_entity analogues|nsubj|site analogues|nmod|end_entity 3.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 buffer|amod|start_entity resolved|nmod|buffer bands|acl|resolved bands|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 control|nmod|start_entity containing|nmod|control plasmid|acl|containing dehydrogenase|nsubj|plasmid dehydrogenase|ccomp|conferred conferred|nsubj|i i|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 taking|dobj|start_entity performed|advcl|taking performed|dobj|study study|acl|determine determine|ccomp|is is|nsubj|reduction reduction|nmod|effects effects|nmod|inhibitors inhibitors|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 ly294002|amod|start_entity cells|nmod|ly294002 domain|nmod|cells introducing|nmod|domain inhibits|csubj|introducing inhibits|advmod|prior prior|nmod|stimulation stimulation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 promotes|nsubj|start_entity promotes|nmod|pathways pathways|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 examined|nmod|start_entity examined|dobj|kinetics kinetics|nmod|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 formulation|compound|start_entity formulation|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 radicals|amod|start_entity converts|dobj|radicals dismutase|acl:relcl|converts dismutase|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 kinases|amod|start_entity kinases|dep|associated associated|nmod|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 scaffold|amod|start_entity developed|nmod|scaffold molecules|acl|developed attenuate|nsubj|molecules attenuate|dobj|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effect|nmod|start_entity effect|dep|inhibitors inhibitors|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 4.000000 0 15.000000 0 0.000000 0 2.000000 0 1.000000 0 conclusions|dep|start_entity constitutes|nsubj|conclusions constitutes|dobj|signal signal|acl:relcl|engages engages|dobj|receptor/pannexin receptor/pannexin|acl|leading leading|xcomp|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 drives|nsubj|start_entity drives|advcl|cell-produced cell-produced|ccomp|provokes provokes|nsubj|hormone hormone|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 angiotensin-ii|compound|start_entity angiotensin-ii|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 8.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 metabolism|compound|start_entity regulating|dobj|metabolism bdnf|acl|regulating efficacy|nmod|bdnf reproduced|nsubjpass|efficacy reproduced|xcomp|suggesting suggesting|ccomp|acted acted|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 3-kinase/pkb|amod|start_entity pathways|nsubj|3-kinase/pkb pathways|advcl|enhancing enhancing|advcl|enhance enhance|nsubj|pathways pathways|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 pathway|compound|start_entity provides|dobj|pathway provides|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 production|compound|start_entity inhibitor|nmod|production effects|nmod|inhibitor estimated|nsubjpass|effects incubated|parataxis|estimated incubated|nmod|ng/ml ng/ml|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 >|advmod|start_entity >|dobj|microm microm|dep|reduced reduced|dobj|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 family|amod|start_entity d|nmod|family member|nmod|d codes|nmod|member codes|nummod|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 4.000000 0 relation|nmod|start_entity relation|acl|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 13.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 determination|compound|start_entity include|dobj|determination include|dobj|gene gene|compound|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 increased|nmod|start_entity increased|dep|% %|nmod|progesterone progesterone|nmod|hormone hormone|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 7.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 release|compound|start_entity kinetics|nmod|release background|nsubj|kinetics background|parataxis|glycoprotein glycoprotein|nsubj|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 species|compound|start_entity species|acl:relcl|mediated mediated|dobj|manner manner|amod|cytotoxicity cytotoxicity|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 actions|nmod|start_entity involve|nsubj|actions involve|dobj|systems systems|nmod|channels channels|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 related|nmod|start_entity formation|acl|related formation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 crossbridges|acl|start_entity develop|dobj|crossbridges develop|nsubj|filament filament|acl|composed composed|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 had|nsubj|start_entity had|dobj|effect effect|nmod|peptide peptide|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 11.000000 0 0.000000 0 1.000000 0 0.000000 0 suppress|nsubj|start_entity suppress|advcl|target target|dobj|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 reported|nsubjpass|start_entity reported|nmod|activation activation|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 excretion|amod|start_entity elevation|nmod|excretion blood|appos|elevation activity|nmod|blood inhibition|dep|activity inhibition|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 action|nmod|start_entity mimicked|nsubjpass|action mimicked|nmod|antagonists antagonists|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 system|compound|start_entity underlie|nsubj|system underlie|dobj|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 start_entity|compound|inhibitor inhibitor|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 12.000000 0 0.000000 0 0.000000 0 0.000000 0 export|compound|start_entity results|nmod|export turn|dobj|results expression|acl:relcl|turn leads|dobj|expression leads|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 remain|xcomp|start_entity ecosystems|acl:relcl|remain draining|dobj|ecosystems observed|xcomp|draining observed|nsubj|nitrate nitrate|appos|- -|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 receptor|compound|start_entity domain|nmod|receptor end_entity|nmod|domain 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 administration|amod|start_entity altered|nmod|administration altered|nsubjpass|volume volume|nmod|mice mice|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 effects|nmod|start_entity investigates|dobj|effects dipeptide|ccomp|investigates dipeptide|dobj|antagonist antagonist|amod|end_entity 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 production|amod|start_entity absence|nmod|production absence|nmod|effect effect|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 397|amod|start_entity phosphorylation|nmod|397 prevented|dobj|phosphorylation prevented|nmod|focal_adhesion_kinase focal_adhesion_kinase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity treatment|nmod|cells cells|acl|expressing expressing|dobj|receptors receptors|nummod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 addition|nmod|start_entity blocked|nsubj|addition blocked|dobj|acceleration acceleration|nmod|decay decay|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 inducing|nmod|start_entity activating|advcl|inducing activating|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 capacity|appos|start_entity capacity|appos|malondialdehyde malondialdehyde|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 response|amod|start_entity associated|nmod|response associated|nsubjpass|variants variants|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 level|compound|start_entity regulates|dobj|level end_entity|acl:relcl|regulates 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 safingol|appos|start_entity inhibitors|dep|safingol use|dep|inhibitors use|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 release|nmod|start_entity role|nmod|release plays|dobj|role plays|nsubj|pannexin-1 pannexin-1|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 influence|compound|start_entity serum|nsubj|influence serum|dobj|levels levels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 dehydrogenase|amod|start_entity aspartate_amino_transferase|appos|dehydrogenase aspartate_amino_transferase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 synthesis|compound|start_entity catalyze|dobj|synthesis isoform|acl:relcl|catalyze end_entity|appos|isoform 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 concentration|compound|start_entity rise|nmod|concentration coupling|dobj|rise pathway|dep|coupling affect|dobj|pathway affect|nsubj|concentrations concentrations|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 17.000000 0 0.000000 0 dehydrogenase|amod|start_entity protein|amod|dehydrogenase protein|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 receptors|amod|start_entity subunit|nmod|receptors end_entity|dep|subunit 0.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 blocked|nmod|start_entity blocked|nmod|inhibition inhibition|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 resistance|amod|start_entity associated|nmod|resistance associated|advmod|end_entity 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 turnover|compound|start_entity role|nmod|turnover plays|dobj|role 24-hydrolase|acl:relcl|plays encodes|dobj|24-hydrolase encodes|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 metabolism|amod|start_entity regulation|nmod|metabolism central|nmod|regulation gene|acl:relcl|central peroxisome_proliferator_activated_receptor_alpha|appos|gene peroxisome_proliferator_activated_receptor_alpha|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 tested|nmod|start_entity tested|nmod|doses doses|nmod|antagonists antagonists|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 counteracted|dobj|start_entity acth|acl|counteracted induced|nsubj|acth end_entity|acl:relcl|induced 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 cells|nmod|start_entity treatment|nmod|cells treatment|appos|specific specific|nmod|kinase kinase|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 collagen|amod|start_entity stimulated|nmod|collagen platelets|acl|stimulated observed|nmod|platelets observed|nsubj|phosphorylation phosphorylation|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 ach|appos|start_entity decreased|nmod|ach decreased|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 killed|nsubj|start_entity killed|dobj|cells cells|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 enzyme|nmod|start_entity inhibition|appos|enzyme reduced|nsubj|inhibition reduced|nmod|mechanism mechanism|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 motif|compound|start_entity domain|nsubj|motif domain|nmod|radiation radiation|acl:relcl|decrease decrease|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 output|compound|start_entity output|nmod|response response|nmod|injections injections|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 accumulation|nmod|start_entity leads|nmod|accumulation leads|nsubj|objective objective|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 neoadjuvant|amod|start_entity trial|amod|neoadjuvant collected|nmod|trial specimens|acl|collected specimens|nummod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 2.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitor|amod|start_entity blocked|nmod|inhibitor blocked|nsubjpass|secretion secretion|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 substitutions|amod|start_entity each|nmod|substitutions tested|dobj|each tested|advcl|define define|nmod|sites sites|nmod|efficiency efficiency|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 application|compound|start_entity adaptation|nmod|application modification|nmod|adaptation modification|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 roles|nmod|start_entity -lsb-|dobj|roles -lsb-|nmod|release release|nmod|calcitonin_gene-related_peptide calcitonin_gene-related_peptide|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 kinases|amod|start_entity locations|nmod|kinases distinct|nmod|locations locus|acl:relcl|distinct q32|appos|locus maps|dobj|q32 maps|nsubj|gene gene|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 decrease|nsubj|start_entity like|ccomp|decrease like|nsubj|inhibitors inhibitors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 10.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity rose|nsubj|levels rose|nmod|/ /|dep|ml ml|nmod|h h|amod|alanine alanine|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 17.000000 0 0.000000 0 phorbol_12-myristate_13-acetate|appos|start_entity phorbol_12-myristate_13-acetate|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 increases|nmod|start_entity cause|nsubj|increases cause|ccomp|kinase kinase|dobj|phosphorylation phosphorylation|nmod|variants variants|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 presence|nmod|start_entity reduced|nmod|presence reduced|xcomp|suggesting suggesting|ccomp|contribute contribute|nsubj|channels channels|amod|end_entity 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 supply|compound|start_entity independent|nmod|supply independent|nsubj|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 administrations|nmod|start_entity studied|nmod|administrations studied|nsubjpass|changes changes|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pyrene|appos|start_entity examined|nmod|pyrene elicit|ccomp|examined elicit|dobj|patterns patterns|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 oxidation|nmod|start_entity precursors|nsubj|oxidation precursors|nmod|hepatic hepatic|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 ability|nmod|start_entity reduce|nsubj|ability reduce|nmod|end_entity 1.000000 0 0.000000 0 5.000000 0 1.000000 0 0.000000 0 9.000000 0 0.000000 0 5.000000 0 3.000000 0 0.000000 0 production|amod|start_entity increase|nmod|production was|nmod|increase was|nsubj|increase increase|nmod|activity activity|nmod|myeloperoxidase myeloperoxidase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibits|nsubj|start_entity inhibits|xcomp|complex complex|nsubj|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 3.000000 0 10.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|ref|which reduce|nsubj|which reduce|dobj|resistance resistance|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|nmod|start_entity damaged|nmod|levels damaged|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 groups|amod|start_entity reduction|nmod|groups produces|dobj|reduction enzyme|acl:relcl|produces activity|appos|enzyme activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 receiving|dobj|start_entity patients|acl:relcl|receiving evaluated|nmod|patients evaluated|dobj|changes changes|nmod|concentrations concentrations|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|advcl|identify identify|dobj|factors factors|acl:relcl|contribute contribute|xcomp|antagonize antagonize|dobj|phosphorylation phosphorylation|amod|end_entity 0.000000 0 0.000000 0 7.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 exposure|compound|start_entity achieved|nmod|exposure mimicked|ccomp|achieved mimicked|nsubj|exposure exposure|dep|agonist agonist|compound|end_entity 1.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 site|nmod|start_entity site|nsubj|activator_protein_1 activator_protein_1|compound|activation activation|nmod|gene gene|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5-ht1a|appos|start_entity 5-ht1a|appos|5-ht2a 5-ht2a|appos|tetralin tetralin|amod|receptors receptors|dep|8-hydroxy-2 8-hydroxy-2|nummod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 release|amod|start_entity acetylcholine|dobj|release bioactive|advcl|acetylcholine bioactive|dobj|release release|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 -rsb-|compound|start_entity -lsb-|nmod|-rsb- inhibitors|acl|-lsb- inhibitors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 1.000000 0 0.000000 0 kinase|compound|start_entity kinase|acl|signaling signaling|nmod|stimulation stimulation|amod|ligand ligand|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 excretion|compound|start_entity excretion|acl|resulting resulting|dobj|loss loss|nmod|regulation regulation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 clearance|compound|start_entity involved|nmod|clearance modulating|advcl|involved end_entity|acl|modulating 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 2.000000 0 secretion|amod|start_entity potentiating|dobj|secretion synergize|advcl|potentiating synergize|advmod|albeit albeit|nmod|extent extent|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentration|nmod|start_entity increase|nmod|concentration observed|nsubjpass|increase observed|nmod|stimulation stimulation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 providing|iobj|start_entity end_entity|acl|providing 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 sar1|compound|start_entity sar1|appos|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|nmod|start_entity depend|nmod|metabolism depend|nsubj|ability ability|nmod|peroxide peroxide|amod|metabolise metabolise|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 concentration|nmod|start_entity increase|dobj|concentration conditions|acl:relcl|increase decreased|nsubj|conditions decreased|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 _|amod|start_entity abrogates|nsubj|_ abrogates|dobj|activation activation|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 7.000000 0 8.000000 0 16.000000 0 1.000000 0 5.000000 0 0.000000 0 receptor|amod|start_entity isoform|compound|receptor isoform|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 using|dobj|start_entity mimicked|xcomp|using mimicked|nmod|antagonism antagonism|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|advcl|fed fed|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 treatment|compound|start_entity receiving|dobj|treatment blocking|advcl|receiving blocking|nmod|level level|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 antiandrogens|dep|start_entity antiandrogens|acl:relcl|compete compete|nmod|end_entity 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 gained|nsubj|start_entity gained|advcl|established established|nsubjpass|vascular_endothelial_growth_factor vascular_endothelial_growth_factor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibit|nsubj|start_entity inhibit|dobj|production production|nmod|end_entity 0.000000 0 3.000000 0 0.000000 0 0.000000 0 17.000000 0 30.000000 0 9.000000 0 0.000000 0 10.000000 0 2.000000 0 reward|compound|start_entity expression|nmod|reward creb|nmod|expression effects|nmod|creb attributed|nsubjpass|effects suggest|ccomp|attributed suggest|nmod|expression expression|nmod|gene gene|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentration|compound|start_entity increased|nsubj|concentration increased|nmod|accumulation accumulation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 activate|nsubj|start_entity activate|dobj|extracellular_signal-regulated_kinase extracellular_signal-regulated_kinase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 synthesis|amod|start_entity critical|nmod|synthesis critical|nsubj|isozyme isozyme|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 downstream|compound|start_entity downstream|nmod|caspase-8 caspase-8|nmod|hemichannels hemichannels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 corrected|nmod|start_entity f508del-cftr|acl|corrected exhibited|nsubj|f508del-cftr exhibited|dobj|characteristics characteristics|amod|similar similar|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 glycoprotein|nmod|start_entity glycoprotein|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 depletion|amod|start_entity depletion|acl|induced induced|nmod|tetrabenazine tetrabenazine|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 rates|nmod|start_entity gaschromatography|appos|rates determined|nmod|gaschromatography determined|nsubjpass|rates rates|nmod|oxygen oxygen|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 biosensors|nmod|start_entity constructed|nsubjpass|biosensors constructed|advcl|monitoring monitoring|dobj|activity activity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 induced|nmod|start_entity induced|nsubj|role role|nmod|histamine histamine|nmod|rostral_hypothalamus rostral_hypothalamus|nmod|release release|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 13.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 androgens|appos|start_entity androgens|acl|acting acting|nmod|androgen_receptor androgen_receptor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 phenotype|compound|start_entity exhibited|dobj|phenotype recapitulated|advcl|exhibited recapitulated|nsubj|loss loss|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 exposure|nmod|start_entity influences|nsubj|exposure influences|dobj|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 channel|compound|start_entity channel|acl|blocking blocking|nmod|transmission transmission|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 utp|compound|start_entity order|appos|utp suggested|nsubj|order suggested|ccomp|play play|nsubj|end_entity 0.000000 0 1.000000 0 2.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 attenuates|nsubj|start_entity attenuates|advcl|inhibiting inhibiting|dobj|production production|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 8.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 cholesterol|compound|start_entity fasting|dobj|cholesterol correlated|advcl|fasting correlated|nsubj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 discrimination|compound|start_entity expression|nmod|discrimination control|nsubj|expression control|nmod|subtypes subtypes|compound|end_entity 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 production|compound|start_entity production|nmod|up-regulation up-regulation|nmod|phospholipase_a2 phospholipase_a2|appos|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 bp|compound|start_entity bp|nmod|rats rats|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 xenobiotics|nmod|start_entity xenobiotics|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 production|compound|start_entity alter|dobj|production alter|nsubj|changes changes|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 8.000000 0 0.000000 0 2.000000 0 10.000000 0 0.000000 0 markedly|compound|start_entity decreased|nsubj|markedly decreased|dobj|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 12.000000 0 2.000000 0 0.000000 0 6.000000 0 0.000000 0 start_entity|appos|endogenous endogenous|acl|ligand ligand|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 ine|appos|start_entity fasting|dobj|ine genotypes|advcl|fasting genotypes|nsubj|c677t c677t|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 4.000000 0 act|nsubj|start_entity receptors|acl:relcl|act unknown|nsubj|receptors unknown|nmod|identification identification|dep|gpr43 gpr43|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effects|nmod|start_entity control|dobj|effects end_entity|acl:relcl|control 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 administration|nmod|start_entity agonists|nsubj|administration agonists|ccomp|increased increased|nsubj|receptors receptors|amod|specific specific|dep|end_entity 1.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 concentration|compound|start_entity maintained|nsubjpass|concentration infusion|acl:relcl|maintained infusion|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 8-pcpt-cgmp|compound|start_entity activation|nmod|8-pcpt-cgmp stimulated|nsubj|activation stimulated|dobj|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 events|compound|start_entity mediated|nsubj|events mediated|advcl|reduces reduces|nsubj|activation activation|nmod|receptors receptors|nummod|end_entity 0.000000 0 0.000000 0 15.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 1.000000 0 0.000000 0 hyperglycemia|nmod|start_entity vasodilation|nmod|hyperglycemia enhancement|nmod|vasodilation suggests|nsubj|enhancement suggests|dobj|activation activation|nmod|system system|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 protein|amod|start_entity blockade|nmod|protein occurs|nmod|blockade occurs|nmod|down-regulation down-regulation|nmod|response response|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|appos|stimulator stimulator|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 11.000000 0 0.000000 0 1.000000 0 6.000000 0 0.000000 0 decreased|nmod|start_entity decreased|nsubj|injection injection|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 transport|compound|start_entity enhances|dobj|transport enhances|nsubj|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 compounds|compound|start_entity inhibit|nsubj|compounds inhibit|dobj|activation activation|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 influx|compound|start_entity induced|dobj|influx induced|nmod|sector sector|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 selected|nsubjpass|start_entity selected|nmod|substrate substrate|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 doses|nmod|start_entity consumed|dobj|doses consumed|nsubj|mice mice|compound|knockout knockout|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 endothelial_nitric_oxide_synthase|amod|start_entity mediator|nsubj|endothelial_nitric_oxide_synthase mediator|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 start_entity|nmod|those those|nmod|duplication duplication|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 availability|compound|start_entity regulated|nmod|availability regulated|nsubjpass|synthesis synthesis|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 0.000000 0 differentially|amod|start_entity contributes|nsubj|differentially explain|ccomp|contributes explain|nsubj|differences differences|compound|end_entity 0.000000 0 0.000000 0 10.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 3.000000 0 addition|nmod|start_entity affect|nmod|addition affect|dobj|secretion secretion|nmod|parathyroid_hormone parathyroid_hormone|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 result|nmod|start_entity considered|nmod|result mediated|ccomp|considered mediated|nsubj|glucocorticoid_receptor glucocorticoid_receptor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2,3,7,8-tetrachlorodibenzo-p-dioxin|appos|start_entity administered|dobj|2,3,7,8-tetrachlorodibenzo-p-dioxin administered|advcl|characterize characterize|nmod|agonists agonists|compound|end_entity 4.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity effect|acl|stimulated stimulated|dobj|concentrations concentrations|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 observed|nmod|start_entity mediated|advcl|observed mediated|nmod|end_entity 5.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 4.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 analyze|dobj|start_entity taken|xcomp|analyze total|ccomp|taken total|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 eggs|compound|start_entity staining|nmod|eggs induced|nmod|staining induced|nsubj|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 antagonists|compound|start_entity profile|nmod|antagonists man|nmod|profile conditions|nmod|man treatment|nmod|conditions utility|nmod|treatment have|dobj|utility have|nsubj|antagonists antagonists|compound|end_entity 0.000000 0 0.000000 0 15.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 1.000000 0 0.000000 0 clearance|compound|start_entity mechanism|nmod|clearance patients|nmod|mechanism depriving|dobj|patients occur|parataxis|depriving fail|xcomp|occur fail|advcl|enrichment enrichment|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 that|nmod|start_entity equal|nmod|that potency|amod|equal reduced|nmod|potency altered|advcl|reduced altered|nsubj|agonist agonist|amod|end_entity 1.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 levels|compound|start_entity explained|nmod|levels explained|nsubj|locus locus|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 p|nmod|start_entity p|nsubj|8 8|acl|p p|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 kd|dep|start_entity kd|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|ccomp|induced induced|dobj|activation activation|appos|independent independent|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 e.g.|dep|start_entity antiandrogens|appos|e.g. antiandrogens|acl:relcl|directed directed|nmod|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nmod|therapy therapy|nmod|patients patients|nmod|rearrangements rearrangements|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 disposal|compound|start_entity action|nmod|disposal measures|nmod|action affected|dobj|measures affected|nsubj|rate rate|nmod|infusion infusion|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 electrolytes|amod|start_entity electrolytes|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 deprivation|compound|start_entity cells|nmod|deprivation uptake|nmod|cells activation|nmod|uptake shifted|nsubj|activation shifted|nmod|change change|nmod|concentration concentration|compound|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 23.000000 0 2.000000 0 1.000000 0 effects|nmod|start_entity transport|nsubj|effects transport|dobj|gene gene|appos|end_entity 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 23.000000 0 2.000000 0 1.000000 0 synthase|compound|start_entity responsible|nsubj|synthase discovered|ccomp|responsible became|advcl|discovered became|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 8.000000 0 responsive|nmod|start_entity metabolites|amod|responsive channel|dobj|metabolites form|ccomp|channel form|nsubj|subunits subunits|appos|end_entity 3.000000 0 0.000000 0 10.000000 0 1.000000 0 0.000000 0 4.000000 0 1.000000 0 3.000000 0 1.000000 0 0.000000 0 generation|compound|start_entity inhibited|parataxis|generation inhibited|dobj|peptide peptide|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 inhibition|nmod|start_entity explore|nmod|inhibition lines|dep|explore lines|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 2.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 biosynthesis|nmod|start_entity suggesting|dobj|biosynthesis increased|xcomp|suggesting increased|nsubj|mrna mrna|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 dose|nmod|start_entity levels|nmod|dose blacks|nmod|levels carrier|nsubj|blacks carrier|nmod|allele allele|acl|associated associated|nmod|capacity capacity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pretreatment|compound|start_entity enhanced|nsubj|pretreatment enhanced|nmod|increases increases|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 application|nmod|start_entity induced|nmod|application flow|acl|induced increase|nmod|flow measuring|dobj|increase involves|xcomp|measuring involves|advcl|developed developed|nsubjpass|novel novel|amod|pharmacodynamic pharmacodynamic|xcomp|measure measure|dobj|non-invasively non-invasively|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibit|nsubj|start_entity inhibit|advcl|targeting targeting|dep|suggesting suggesting|ccomp|worthy worthy|nsubj|mechanism mechanism|nmod|regulation regulation|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 %|nummod|start_entity energy|compound|% had|nsubj|energy had|advcl|had had|nsubj|weight weight|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 agonists|amod|start_entity produced|nmod|agonists those|acl|produced produce|nmod|those produce|nmod|end_entity 0.000000 0 0.000000 0 13.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 suppressed|nmod|start_entity upregulated|advcl|suppressed upregulated|nsubjpass|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 decreased|dobj|start_entity decreased|nsubj|addition addition|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 dose|compound|start_entity variation|nmod|dose contributors|nmod|variation contributors|nsubj|variations variations|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 upregulated|nmod|start_entity upregulated|nsubjpass|production production|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 addition|acl|start_entity increased|nsubj|addition increased|dobj|contents contents|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transport|compound|start_entity enzyme|nmod|transport variant|appos|enzyme variant|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 metabolite|nmod|start_entity beta-estradiol_17beta-d-glucuronide|appos|metabolite identified|nsubjpass|beta-estradiol_17beta-d-glucuronide identified|nmod|substrate substrate|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 level|compound|start_entity raising|dobj|level found|advcl|raising found|nmod|cells cells|nmod|receptors receptors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 migration|amod|start_entity migration|nmod|cells cells|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 release|compound|start_entity release|nmod|stimulation stimulation|nummod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 caerulein|amod|start_entity injections|nmod|caerulein induced|nmod|injections intake|acl|induced reduction|nmod|intake antagonised|nsubjpass|reduction antagonised|nmod|dose dose|nmod|antagonist antagonist|compound|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 resulting|nmod|start_entity that|acl|resulting similar|nmod|that similar|nsubj|suppression suppression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 metabolism|compound|start_entity improvement|nmod|metabolism associated|nmod|improvement known|xcomp|associated end_entity|acl|known 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 ligands|nmod|start_entity transports|dobj|ligands transports|nsubj|signaling signaling|compound|end_entity 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 induced|nmod|start_entity hypercholesterolemia|acl|induced regulator|nmod|hypercholesterolemia studied|nsubjpass|regulator shown|advcl|studied cholesterol_acyltransferase_2|acl|shown cholesterol_acyltransferase_2|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 treatment|amod|start_entity caused|nsubj|treatment caused|nmod|dexamethasone dexamethasone|nmod|mrna mrna|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 application|nmod|start_entity appeared|nmod|application e.p.s.p.|acl:relcl|appeared inhibition|nmod|e.p.s.p. blocked|dobj|inhibition blocked|nsubj|spiperone spiperone|appos|antagonist antagonist|amod|end_entity 1.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 half-sites|amod|start_entity interaction|nmod|half-sites interaction|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 13.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 aldehydes|appos|start_entity detoxifies|dobj|aldehydes detoxifies|nsubj|aldehyde_dehydrogenase_2 aldehyde_dehydrogenase_2|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 metabolism|amod|start_entity involved|nmod|metabolism genes|dep|involved genes|appos|c677t c677t|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 4.000000 0 start_entity|acl|oxidation oxidation|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 effects|compound|start_entity attenuating|dobj|effects attenuating|nmod|caspase-3 caspase-3|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 mediators|nmod|start_entity mediators|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 species|compound|start_entity contained|dobj|species cells|acl:relcl|contained cells|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 treated|nmod|start_entity rats|acl|treated neurons|nmod|rats showed|nsubj|neurons showed|dobj|synthesis synthesis|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 enzymes|compound|start_entity enzymes|nummod|end_entity 1.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|parataxis|occurs occurs|xcomp|due due|nmod|mutation mutation|nmod|end_entity 0.000000 0 0.000000 0 7.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 derivative|nmod|start_entity derivative|acl:relcl|exhibit exhibit|dobj|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 tolerance|compound|start_entity assessed|nmod|tolerance test|amod|assessed diet|dep|test diet|nmod|response response|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 handling|amod|start_entity handling|appos|consequence consequence|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 scavenger|amod|start_entity manganese_superoxide_dismutase|acl:relcl|scavenger manganese_superoxide_dismutase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 receptors|compound|start_entity regulation|nmod|receptors cytoskeletal|dobj|regulation cytoskeletal|nmod|neurons neurons|nummod|end_entity 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 function|nmod|start_entity line|nmod|function produced|nmod|line produced|nsubj|manipulations manipulations|nmod|val val|compound|end_entity 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 exogenous|acl|start_entity stimulate|nmod|exogenous stimulate|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 anesthesia|amod|start_entity determine|nmod|anesthesia performing|xcomp|determine evaluated|advcl|performing evaluated|dobj|properties properties|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 deposition|compound|start_entity deposition|nmod|mrna mrna|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nsubj|cells cells|nmod|levels levels|nmod|release release|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 injection|compound|start_entity increases|nmod|injection increases|nsubj|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 association|nmod|start_entity polymorphism|amod|association polymorphism|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 effects|nmod|start_entity most|nmod|effects mediated|nsubjpass|most mediated|nmod|expression expression|amod|binding binding|nmod|aryl_hydrocarbon_receptor aryl_hydrocarbon_receptor|appos|end_entity 4.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 overproduction|compound|start_entity luteinizing|nsubj|overproduction examine|ccomp|luteinizing performed|dep|examine performed|advcl|suppress suppress|advcl|use use|nmod|cetrorelix cetrorelix|appos|antagonist antagonist|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 relating|xcomp|start_entity allele|parataxis|relating allele|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|ccomp|correlate correlate|nmod|dose dose|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 antagonist|compound|start_entity effects|nmod|antagonist compare|dobj|effects compare|nmod|inhibitor inhibitor|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 p-dioxin|appos|start_entity 2,3,7,8-tetracholordibenzo|dep|p-dioxin response|amod|2,3,7,8-tetracholordibenzo aryl_hydrocarbon_receptor|nmod|response activation|nmod|aryl_hydrocarbon_receptor induces|nsubj|activation induces|dobj|population population|nmod|cd25 cd25|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 role|nmod|start_entity due|nmod|role phenotype|amod|due result|nmod|phenotype result|nsubj|loss loss|nmod|function function|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 3.000000 0 transporter|compound|start_entity transporter|appos|resistance resistance|dep|gene gene|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 deficiency|amod|start_entity role|nmod|deficiency argue|nmod|role argue|nsubj|concentrations concentrations|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 metabolism|nmod|start_entity responsible|nmod|metabolism isoform|amod|responsible isoform|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 reduced|nsubj|start_entity ligand|ccomp|reduced ligand|nsubj|administration administration|nmod|end_entity 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|dobj|392 392|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 resistance|compound|start_entity selected|nmod|resistance selected|nsubjpass|isolate isolate|nmod|fac8 fac8|acl:relcl|carries carries|dobj|amplification amplification|nmod|gene gene|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 sites|nmod|start_entity has|dobj|sites has|nsubj|end_entity 1.000000 0 0.000000 0 1.000000 0 2.000000 0 2.000000 0 6.000000 0 9.000000 0 7.000000 0 2.000000 0 1.000000 0 receptor|amod|start_entity variations|nmod|receptor variations|amod|5-ht_transporter 5-ht_transporter|dep|slc6a4 slc6a4|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 competing|nmod|start_entity functions|dep|competing corepressors|nsubj|functions antagonist|ccomp|corepressors antagonist|compound|end_entity 1.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 mg|nmod|start_entity dst|dep|mg investigated|nmod|dst investigated|dobj|responses responses|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|ccomp|used used|xcomp|measure measure|nmod|indicators indicators|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 sessions|compound|start_entity appear|nmod|sessions appear|advcl|indicated indicated|nmod|injection injection|nmod|antagonist antagonist|compound|end_entity 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|acl|suggesting suggesting|ccomp|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 receptors|compound|start_entity stimulation|nmod|receptors produced|nmod|stimulation activation|acl|produced antagonization|nmod|activation caused|nsubj|antagonization caused|nmod|injections injections|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 treated|nmod|start_entity cells|acl|treated develop|nsubj|cells develop|dobj|response response|acl|compensating compensating|dobj|activity activity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibited|nmod|start_entity receptor|acl:relcl|inhibited receptor|nummod|end_entity 0.000000 0 1.000000 0 3.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 presence|nmod|start_entity incubated|nmod|presence seen|advcl|incubated indicated|ccomp|seen indicated|nsubjpass|effects effects|nmod|dfmo dfmo|nmod|macrophages macrophages|acl|resulted resulted|nmod|reduction reduction|nmod|levels levels|acl|caused caused|nmod|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 providing|dobj|start_entity role|acl|providing plays|dobj|role plays|nsubj|glucose-6-phosphatase glucose-6-phosphatase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 excretion|compound|start_entity assessed|nmod|excretion response|acl|assessed response|nmod|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 group|compound|start_entity suppression|nmod|group higher|nmod|suppression higher|nsubj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 consumption|compound|start_entity contributed|nsubjpass|consumption contributed|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inducible|nsubj|start_entity inducible|dobj|protein protein|appos|mrna mrna|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 homeostasis|nmod|start_entity measures|nmod|homeostasis familial|advcl|measures familial|csubj|circulating circulating|dobj|levels levels|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 -rsb-|amod|start_entity induced|nmod|-rsb- preneoplastic_lesions|acl|induced protein|nmod|preneoplastic_lesions expression|dep|protein expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 stimulation|compound|start_entity induced|nmod|stimulation synthesis|acl|induced synthesis|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 reduces|nsubj|start_entity reduces|advcl|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 4.000000 0 0.000000 0 1.000000 0 0.000000 0 elimination|compound|start_entity occurs|nsubj|elimination occurs|dep|catalyzed catalyzed|nmod|alcohol_dehydrogenase alcohol_dehydrogenase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 associations|nmod|start_entity addition|nmod|associations higher|nmod|addition higher|nmod|women women|nmod|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 sensing|nmod|start_entity defect|nmod|sensing defect|acl|caused caused|nmod|mutation mutation|nmod|gene gene|amod|end_entity 2.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 6.000000 0 1.000000 0 1.000000 0 4.000000 0 0.000000 0 norbinaltorphimine|appos|start_entity norbinaltorphimine|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 domain|compound|start_entity mediates|nsubj|domain mediates|ccomp|/ /|nsubj|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity number|nmod|effects mediated|nsubjpass|number mediated|nmod|activation activation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 yields|compound|start_entity data|nmod|yields data|dep|time time|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 reduced|nmod|start_entity concluded|advcl|reduced concluded|ccomp|measures measures|nsubj|reduction reduction|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 production|amod|start_entity inhibited|dobj|production inhibited|nsubj|inhibitor inhibitor|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 5.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 kinase|compound|start_entity kinase|nmod|receptor receptor|amod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|dep|start_entity effect|nmod|response response|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod:poss|start_entity some|nmod|effects mediated|nsubjpass|some raising|ccomp|mediated increases|advcl|raising increases|dobj|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthesis|amod|start_entity used|nmod|synthesis used|nsubjpass|independent independent|nmod|receptors receptors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 hepatotoxicity|compound|start_entity clarify|nmod|hepatotoxicity clarify|dobj|role role|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptors|compound|start_entity composition|nmod|receptors switch|nmod|composition parallel|nmod|switch occurs|nmod|parallel occurs|nmod|end_entity 0.000000 0 0.000000 0 12.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 neurotransmitters|compound|start_entity responsible|nmod|neurotransmitters responsible|nsubj|vesicular_monoamine_transporter vesicular_monoamine_transporter|appos|type_2 type_2|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 3.000000 0 equivalents|compound|start_entity equivalents|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 phosphorylation|amod|start_entity inhibited|nsubjpass|phosphorylation inhibited|nmod|sb-203580 sb-203580|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 thyrotoxicosis|appos|start_entity action|nmod|thyrotoxicosis evaluate|nmod|action evaluate|nsubj|technique technique|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 isoform|amod|start_entity activity|dep|isoform activity|nmod|levels levels|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 decreased|nmod|start_entity decreased|nsubjpass|contents contents|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibits|nsubj|start_entity inhibits|nmod|accumulation accumulation|nmod|endogenous endogenous|acl|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 methylenethf|amod|start_entity reduction|nmod|methylenethf catalyzed|nsubjpass|reduction catalyzed|nmod|reductase reductase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 concentrations|compound|start_entity concentrations|nmod|cells cells|acl|activated activated|nmod|lipopolysaccharide lipopolysaccharide|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 level|compound|start_entity regulating|dobj|level drug|acl|regulating agonist|appos|drug agonist|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 mg/kg|nmod|start_entity administration|nmod|mg/kg micrograms/kg|nmod|administration micrograms/kg|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 resistance|compound|start_entity overcomes|dobj|resistance overcomes|nmod|cells cells|acl:relcl|overexpress overexpress|xcomp|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 had|nsubj|start_entity had|nmod|inhalation inhalation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 p|nmod|start_entity haplotypes|dep|p haplotypes|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 receptor|amod|start_entity proto-oncogene|appos|receptor product|nmod|proto-oncogene product|nsubj|receptor receptor|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transporter|compound|start_entity transporter|acl:relcl|colocalizes colocalizes|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 myristate_acetate|appos|start_entity added|nsubj|myristate_acetate added|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 important|nsubj|start_entity important|nmod|action action|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 receptor|amod|start_entity link|nmod|receptor function|nmod|link function|nsubj|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 tolerance|amod|start_entity up-regulated|nmod|tolerance up-regulated|nsubj|expressions expressions|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 labeling|nsubj|start_entity labeling|dobj|immunolabeling immunolabeling|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 interactions|nmod|start_entity interactions|nmod|receptor receptor|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|nmod|start_entity regulates|nsubj|uptake regulates|dobj|status status|nmod|factor factor|acl:relcl|regulates regulates|dobj|translation translation|nmod|mrna mrna|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 dehydrogenase|amod|start_entity dehydrogenase|acl|encoded encoded|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 infusion|nmod|start_entity approximate|nmod|infusion approximate|nsubj|c c|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 depletion|amod|start_entity indicator|nmod|depletion indicator|advcl|level level|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 pinometostat|appos|start_entity pinometostat|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 correlated|nmod|start_entity correlated|nsubjpass|changes changes|nmod|activity activity|nmod|isoform isoform|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 forms|nmod|start_entity accumulation|nmod|forms causes|dobj|accumulation light|acl:relcl|causes stimulated|nsubj|light stimulated|dobj|activities activities|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 studied|nmod|start_entity studied|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 attenuates|nummod|start_entity acute|nmod:npmod|attenuates rejection|amod|acute inhibitor|dobj|rejection inhibitor|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 availability|compound|start_entity responses|nmod|availability controls|dobj|responses complex|acl:relcl|controls complex|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 actions|nmod|start_entity suppressed|dobj|actions precipitated|advcl|suppressed precipitated|nsubj|balance balance|amod|upregulated upregulated|dep|expression expression|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 domain|compound|start_entity encompasses|dobj|domain complex|acl:relcl|encompasses complex|nmod|peptide peptide|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 protein|dep|start_entity adipocytokines|appos|protein adipocytokines|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 13.000000 0 0.000000 0 start_entity|nsubj|none none|nmod|patients patients|acl|tested tested|nmod|genotypes genotypes|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 dependence|compound|start_entity risk|nmod|dependence modify|dobj|risk modify|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 coloaded|nmod|start_entity coloaded|xcomp|modulate modulate|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 administration|nmod|start_entity attenuates|nsubj|administration attenuates|dobj|hearing_loss hearing_loss|nmod|induction induction|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nsubj|development development|nmod|resistance resistance|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pathway|compound|start_entity polymorphisms|nmod|pathway influence|nmod|polymorphisms influence|appos|hpgd/slco2a1/abcc4 hpgd/slco2a1/abcc4|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 synthase|amod|start_entity constitutive|dep|synthase constitutive|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 analogs|amod|start_entity group|nmod|analogs interacts|nmod|group interacts|nmod|structures structures|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 exposed|nmod|start_entity cells|acl|exposed observed|nmod|cells observed|nsubjpass|inductions inductions|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 therapy|compound|start_entity therapy|nmod|characteristics characteristics|nmod|subfraction subfraction|nmod|patients patients|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 ability|nmod|start_entity contribute|nmod|ability contribute|xcomp|inhibit inhibit|dobj|production production|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 sensitize|nmod|start_entity indicate|advcl|sensitize indicate|ccomp|collaborate collaborate|xcomp|enhance enhance|dobj|formation formation|acl|facilitated facilitated|nmod|depletion depletion|acl|mediated mediated|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|amod|start_entity observed|nmod|treatment promoter|acl:relcl|observed promoter|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 given|advmod|start_entity given|nsubjpass|inhibitor inhibitor|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|compound|start_entity lead|nmod|metabolism lead|nsubj|alleles alleles|nmod|cyp2c9 end_entity|appos|cyp2c9 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibited|nsubj|start_entity inhibited|nmod|that that|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|acl:relcl|kinases kinases|dobj|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 tract|amod|start_entity encodes|dobj|tract repeat|acl:relcl|encodes repeat|dep|protein protein|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 used|nsubjpass|start_entity used|nmod|inhibitor inhibitor|nmod|cytochrome_p450 cytochrome_p450|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity prevented|dobj|effects mediated|advcl|prevented mediated|nmod|receptors receptors|nummod|end_entity 2.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 production|nmod|start_entity reflecting|dobj|production accompanied|xcomp|reflecting accompanied|nmod|mrna mrna|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 5.000000 0 2.000000 0 10.000000 0 absorption|amod|start_entity inhibits|dobj|absorption inhibits|nmod|cells cells|acl|modulating modulating|dobj|interaction interaction|nmod|promoter promoter|amod|c-myb c-myb|nmod|cotransporter cotransporter|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 exhibited|nsubj|start_entity exhibited|dobj|inhibition inhibition|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 release|dobj|start_entity release|advcl|mimic mimic|dobj|secretion secretion|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 receptor|compound|start_entity level|nmod|receptor level|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 hundred|nmod|start_entity stained|nsubjpass|hundred stained|nmod|antibodies antibodies|nmod|ae1/ae3 ae1/ae3|appos|prostate-specific_antigen prostate-specific_antigen|appos|androgen_receptor androgen_receptor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|ccomp|used used|nmod|suppression suppression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 showed|advcl|start_entity showed|dobj|absence absence|nmod|activity activity|nummod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 0.000000 0 6.000000 0 synthase|compound|start_entity expression|nmod|synthase chronic_gastritis|nmod|expression associated|nsubjpass|chronic_gastritis associated|nmod|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 spare|dobj|start_entity found|ccomp|spare found|xcomp|indicating indicating|ccomp|excluded excluded|nsubjpass|synergism synergism|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 infusion|nmod|start_entity affect|nsubj|infusion affect|advcl|added added|nsubjpass|inhibitor inhibitor|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 neurons|compound|start_entity inhibit|nsubj|neurons inhibit|dobj|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 15.000000 0 0.000000 0 0.000000 0 14.000000 0 0.000000 0 inhibitor|compound|start_entity effect|nmod|inhibitor investigated|dobj|effect -1|dep|investigated -1|nsubj|-3 -3|dep|piperidine_carboxylic_acid piperidine_carboxylic_acid|nmod|model model|nmod|death death|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 effects|nmod:poss|start_entity characteristics|nmod|effects examined|dobj|characteristics examined|advcl|luteinizing luteinizing|nmod|pulses pulses|nmod|gonadotropin-releasing_hormone gonadotropin-releasing_hormone|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 induced|nmod|start_entity induced|nsubjpass|level level|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 transport|compound|start_entity reduced|dobj|transport reduced|nmod|cells cells|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 channel|compound|start_entity functioning|nmod|channel addition|acl|functioning plays|nmod|addition plays|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 11.000000 0 0.000000 0 0.000000 0 therapy|nsubj|start_entity therapy|nmod|treatment treatment|nmod|patients patients|nmod|genes genes|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 summary|nmod|start_entity summary|nmod|patients patients|nmod|alteration-positive alteration-positive|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibit|nsubj|start_entity inhibit|dobj|phosphatidylinositol-3-kinase phosphatidylinositol-3-kinase|appos|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 14.000000 0 0.000000 0 1.000000 0 0.000000 0 acyltransferase|amod|start_entity that|dep|acyltransferase end_entity|dobj|that 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|amod|start_entity role|nmod|metabolism plays|dobj|role plays|nsubj|steroid_sulfatase steroid_sulfatase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 complex|compound|start_entity assembly|nmod|complex involved|nmod|assembly involved|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 concentrations|nmod|start_entity low|nsubj|concentrations elevated|advcl|low elevated|nsubj|levels levels|nmod|hpr hpr|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 delivery|nmod|start_entity mediated|nsubjpass|delivery mediated|nmod|protein protein|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 2.000000 0 0.000000 0 treatment|dep|start_entity treatment|nmod|mice mice|nmod|inhibitors inhibitors|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 apolipoprotein_e|compound|start_entity apolipoprotein_e|appos|apoe apoe|dep|protein protein|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 control|compound|start_entity men|nmod|control end_entity|nmod|men 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 level|nmod|start_entity increase|nmod|level paralleled|nmod|increase paralleled|nsubjpass|migration migration|amod|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 targeted|nsubjpass|start_entity targeted|dobj|inhibitors inhibitors|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 resistant|nsubj|start_entity resistant|nsubj|selective selective|compound|end_entity 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 influence|appos|start_entity influence|dep|subunit subunit|compound|end_entity 0.000000 0 0.000000 0 15.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 1.000000 0 0.000000 0 amount|nmod|start_entity greater|nsubj|amount greater|nmod|that that|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 developed|nmod|start_entity developed|nsubjpass|agonists agonists|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 exhibited|nmod|start_entity mediated|parataxis|exhibited mediated|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 9.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity humans|nmod|treatment conducted|nmod|humans conducted|nsubjpass|studies studies|nmod|effects effects|nmod|estrogen estrogen|nmod|regulation regulation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 channels|compound|start_entity regulates|dobj|channels interpretation|dep|regulates requires|nsubj|interpretation requires|ccomp|have have|dobj|cryptic cryptic|appos|channels channels|acl:relcl|stimulated stimulated|nmod|camp camp|nmod|presence presence|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 15.000000 0 3.000000 0 1.000000 0 start_entity|acl|associated associated|advmod|irrespective irrespective|nmod|presence presence|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 birthweight|appos|start_entity birthweight|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 9.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 transportation|compound|start_entity protein|nmod|transportation protein|nsubj|niemann-pick_c1-like_1 niemann-pick_c1-like_1|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 1.000000 0 0.000000 0 residues|amod|start_entity different|nsubj|residues known|parataxis|different known|nsubjpass|molecules molecules|acl|comprising comprising|dobj|family family|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 disease|amod|start_entity inhibitor|nmod|disease inhibitor|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 %|nmod|start_entity corresponded|nmod|% -1|acl:relcl|corresponded lipid_p|dep|-1 ms.|nsubj|lipid_p ms.|dep|375 375|nsubj|activation activation|amod|latency latency|nmod|onset onset|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 secretion|amod|start_entity required|nsubj|secretion required|advcl|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 kinase|amod|start_entity control|nsubj|kinase control|dobj|sets sets|nmod|events events|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 blocked|nsubj|start_entity blocked|advcl|suggesting suggesting|ccomp|induces induces|advcl|activating activating|nmod|pathway pathway|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 0.000000 0 uric_acid|nmod|start_entity serum|acl|uric_acid reliable|nmod|serum reliable|nsubj|method method|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 ins|nsubj|start_entity ins|dep|mediated mediated|nmod|alteration alteration|nmod|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 effect|nmod|start_entity secretion|dep|effect secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|compound|start_entity improved|nsubj|metabolism improved|advcl|reduced reduced|nsubjpass|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 kinase|amod|start_entity kinase|nmod|receptor receptor|amod|end_entity 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nmod|subunit subunit|nmod|dimer dimer|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibited|dep|start_entity inhibited|nsubj|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 8.000000 0 10.000000 0 28.000000 0 2.000000 0 2.000000 0 1.000000 0 receptor|amod|start_entity member|nmod|receptor complex|nmod|member family|amod|complex forming|dobj|family act|advcl|forming act|nsubj|smad3 smad3|appos|one one|nmod|proteins proteins|nmod|pathway pathway|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 levels|compound|start_entity membrane|dobj|levels membrane|nsubj|function function|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 investigate|nmod|start_entity investigate|dobj|expression expression|nmod|end_entity 6.000000 0 0.000000 0 1.000000 0 5.000000 0 1.000000 0 24.000000 0 1.000000 0 0.000000 0 6.000000 0 0.000000 0 receptors|compound|start_entity end_entity|acl:relcl|receptors 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 tolerance|compound|start_entity unaffected|nsubj|tolerance unaffected|nmod|changes changes|nmod|dependent dependent|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 homologs|amod|start_entity gene|nmod|homologs induction|nmod|gene activities|nmod|induction parallel|nsubj|activities parallel|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 11.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 camptothecin|appos|start_entity methods|dep|camptothecin investigate|nsubj|methods investigate|dobj|regulation regulation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 kinase|amod|start_entity lck|appos|kinase hyperphosphorylated|nsubjpass|lck hyperphosphorylated|nmod|absence absence|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 start_entity|acl:relcl|consistent consistent|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 tunnel|amod|start_entity reach|nmod|tunnel suggest|ccomp|reach suggest|nsubj|experiments experiments|nmod|inhibitors inhibitors|nmod|site site|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 cav-1|compound|start_entity cav-1|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptors|amod|start_entity expressions|nmod|receptors show|nsubj|expressions operates|advcl|show operates|dobj|concentrations concentrations|amod|independent independent|nmod|estradiol_receptor estradiol_receptor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibits|nsubj|start_entity inhibits|ccomp|reversible reversible|nsubj|form form|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 availability|compound|start_entity plays|nmod|availability plays|nsubj|factor factor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 cells|amod|start_entity reached|nsubj|cells reached|advcl|detected detected|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 modulated|nmod|start_entity function|ccomp|modulated function|nsubj|androgen_receptor androgen_receptor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 the|nmod|start_entity accommodate|dobj|the undergoes|advcl|accommodate undergoes|parataxis|observed observed|nmod|chain chain|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 expression|nmod|start_entity promotion|nmod|expression surface|nsubj|promotion surface|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthase-1|compound|start_entity form|nsubj|synthase-1 form|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 patients|amod|start_entity testing|nmod|patients testing|nummod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 mediators|nmod|start_entity interacts|dobj|mediators interacts|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 presence|nmod|start_entity increased|nsubj|presence increased|advcl|possibly possibly|nmod|inhibition inhibition|nmod|isozyme isozyme|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 catabolizes|nmod|start_entity enzyme|acl:relcl|catabolizes heme_oxygenase-1|dep|enzyme heme_oxygenase-1|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 administration|nmod|start_entity analysed|nmod|administration paraxanthine/caffeine|acl:relcl|analysed estimated|nmod|paraxanthine/caffeine estimated|nsubjpass|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 elevation|nmod|start_entity leading|nmod|elevation receptor|amod|leading receptor|ref|which promote|nsubj|which promote|dobj|suppression suppression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 outcomes|amod|start_entity influence|dobj|outcomes influence|nsubj|polymorphisms polymorphisms|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 transport|compound|start_entity results|nmod|transport results|nsubj|absence absence|nmod|cf_transmembrane_conductance_regulator cf_transmembrane_conductance_regulator|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 15.000000 0 3.000000 0 1.000000 0 metabolism|amod|start_entity metabolism|acl|lacking lacking|dobj|alcohol_dehydrogenase alcohol_dehydrogenase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 restriction|compound|start_entity infused|nmod|restriction unaltered|advcl|infused response|dep|unaltered response|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 dismutases|amod|start_entity role|nmod|dismutases indicates|nsubj|role indicates|ccomp|independent independent|nsubj|effect effect|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 cells|nmod|start_entity pretreatment|nmod|cells pretreatment|appos|inhibitor inhibitor|nmod|signaling signaling|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 antagonist|amod|start_entity ici_182|appos|antagonist attenuated|nsubj|ici_182 attenuated|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentrations|nmod|start_entity exposed|nmod|concentrations induced|advcl|exposed induced|nsubjpass|mrnas mrnas|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 drinkers|compound|start_entity hypertension|nmod|drinkers pressure|nmod|hypertension influences|dobj|pressure influences|nsubj|genotype genotype|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 conversion|nmod|start_entity catalyzing|dobj|conversion involved|xcomp|catalyzing involved|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 index|nmod|start_entity end_entity|nmod|index 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 efficacy|compound|start_entity polymorphisms|nmod|efficacy polymorphisms|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 effect|nmod|start_entity mechanism|nmod|effect demonstrate|dobj|mechanism demonstrate|advcl|modulating modulating|dobj|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitor|nsubj|start_entity inhibitor|nmod|attachment attachment|nmod|receptor receptor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 haart|amod|start_entity count|nmod|haart count|nsubj|t-lymphocyte t-lymphocyte|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 34|amod|start_entity terminates|nmod|34 species|acl:relcl|terminates species|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 ac220|appos|start_entity treated|nmod|ac220 treated|nsubjpass|cells cells|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 kinases|amod|start_entity stimulates|dobj|kinases show|ccomp|stimulates exciting|dep|show exciting|nsubj|_ _|appos|focal_adhesion_kinase focal_adhesion_kinase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhalation|amod|start_entity effects|nmod|inhalation effects|nmod|mice mice|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 generation|nsubj|start_entity generation|dep|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 5.000000 0 2.000000 0 10.000000 0 stores|compound|start_entity decrease|nmod|stores indicated|dobj|decrease micrograms/l|acl:relcl|indicated saturation|dep|micrograms/l saturation|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 oxidase|compound|start_entity component|nmod|oxidase expression|appos|component expression|nmod|end_entity 0.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 cytosine|nmod|start_entity deamination|nmod|cytosine one|nsubj|deamination enzyme|advcl|one enzyme|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 responsiveness|amod|start_entity impaired|dobj|responsiveness impaired|nsubj|patients patients|acl|possessing possessing|dobj|allele allele|compound|end_entity 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 inhibitors|dep|start_entity _|dep|inhibitors effects|nmod|_ compared|dobj|effects compared|nmod|naproxen naproxen|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptor|amod|start_entity subunit|dobj|receptor subunit|nsubj|molecule molecule|appos|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 kinases|amod|start_entity proteins|nmod|kinases phosphorylation|nmod|proteins one|nsubj|phosphorylation evidence|dep|one account|nmod|evidence account|nsubj|activity activity|nummod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 variant|nmod|start_entity dehydrogenase|nsubj|variant dehydrogenase|dobj|methylation methylation|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 species|compound|start_entity increase|nmod|species increase|acl:relcl|lead lead|nmod|induction induction|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 blockers|nmod|start_entity found|nmod|blockers chemotype|acl|found distinct|nmod|chemotype cystic_fibrosis|acl:relcl|distinct treatment|nmod|cystic_fibrosis represent|nmod|treatment represent|dobj|class class|nmod|blockers blockers|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 pro-adrenomedullin|dep|start_entity pro-adrenomedullin|dep|end_entity 0.000000 0 0.000000 0 1.000000 0 2.000000 0 1.000000 0 26.000000 0 0.000000 0 0.000000 0 20.000000 0 2.000000 0 wk|nmod|start_entity showing|nmod|wk achieved|advcl|showing achieved|dobj|sensitivity sensitivity|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity due|nmod|treatment occupancy|amod|due occupancy|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 kinases|amod|start_entity approach|appos|kinases approach|parataxis|assessed assessed|nsubjpass|alpha alpha|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 containing|dobj|start_entity containing|advcl|supporting supporting|ccomp|maintains maintains|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 16.000000 0 1.000000 0 1.000000 0 metabolized|nsubjpass|start_entity metabolized|nmod|eicosanoids eicosanoids|nmod|enzymes enzymes|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 s-1|nmod|start_entity had|nsubj|s-1 had|ccomp|exhibited exhibited|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 depletion|nmod|start_entity expressed|nsubj|depletion expressed|dobj|channels channels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 intake|compound|start_entity regulation|nmod|intake regulation|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 receiving|xcomp|start_entity patients|acl|receiving performed|nmod|patients *|acl:relcl|performed *|compound|end_entity 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 believed|nsubjpass|start_entity believed|nmod|extent extent|nmod|mechanism mechanism|acl:relcl|independent independent|nmod|ability ability|acl|inhibit inhibit|dobj|monoamine_oxidase-b monoamine_oxidase-b|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 0.000000 0 genotype|compound|start_entity interaction|nmod|genotype effect|dep|interaction effect|nmod|supplementation supplementation|nmod|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 14a-demethylases|amod|start_entity comprise|nsubj|14a-demethylases comprise|dobj|family family|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity reduce|nsubj|treatment demonstrated|ccomp|reduce demonstrated|xcomp|suggesting suggesting|dobj|role role|nmod|mammalian_target_of_rapamycin mammalian_target_of_rapamycin|appos|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 8.000000 0 18.000000 0 2.000000 0 2.000000 0 1.000000 0 homeostasis|compound|start_entity control|nmod|homeostasis interfering|nmod|control inhibits|advcl|interfering inhibits|nsubj|protein_tyrosine_phosphatase_1b protein_tyrosine_phosphatase_1b|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 estrogen|nmod|start_entity synthesizes|dobj|estrogen -rsb-|acl:relcl|synthesizes -rsb-|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 cancelled|nsubj|start_entity cancelled|nmod|upregulation upregulation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 dependence|compound|start_entity confers|nsubj|dependence confers|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 17.000000 0 0.000000 0 start_entity|appos|kinase kinase|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 6.000000 0 8.000000 0 18.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|compound|start_entity uptake|acl|mediated mediated|nmod|transporter transporter|compound|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 17.000000 0 5.000000 0 0.000000 0 start_entity|nsubj|identification identification|nmod|ki23819 ki23819|appos|inhibitor inhibitor|nmod|activity activity|nmod|receptor receptor|compound|end_entity 0.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 start_entity|nmod|levels levels|nmod|cd40_ligand cd40_ligand|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 insufficiency|compound|start_entity marker|nmod|insufficiency marker|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 response|nmod|start_entity migration|nmod|response migration|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity affects|dobj|levels affects|parataxis|understood understood|nsubjpass|properties properties|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 homeostasis|compound|start_entity mechanisms|nmod|homeostasis role|nmod|mechanisms plays|dobj|role plays|nsubj|regulation regulation|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 administration|compound|start_entity occurred|nmod|administration occurred|nsubj|increase increase|nmod|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 inhibits|nsubj|start_entity assessed|ccomp|inhibits assessed|advcl|regulated regulated|nmod|secretion secretion|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 lps|compound|start_entity lps|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 depleted|nmod|start_entity converts|advcl|depleted converts|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 depletion|compound|start_entity elevated|nmod|depletion elevated|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 11.000000 0 0.000000 0 4.000000 0 12.000000 0 1.000000 0 diminished|nsubj|start_entity diminished|dobj|rate rate|acl|caffeine caffeine|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8-hydroxydeoxyguanosine|dep|start_entity microalbumin|appos|8-hydroxydeoxyguanosine microalbumin|appos|myeloperoxidase myeloperoxidase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 regulate|dobj|start_entity regulate|nsubj|proteins proteins|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity treatment|nmod|expression expression|amod|binding binding|nmod|receptors receptors|amod|cannabinoid cannabinoid|dep|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 prevented|nsubj|start_entity prevented|dobj|expression expression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|acl:relcl|involved involved|nmod|release release|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 lipids|compound|start_entity end_entity|nmod|lipids 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 13.000000 0 0.000000 0 breakdown|nmod|start_entity breakdown|dep|interaction interaction|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 induction|amod|start_entity inhibited|nsubj|induction inhibited|advcl|blocked blocked|nsubjpass|induction induction|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 dehydrogenase|nsubj|start_entity dehydrogenase|dobj|isozyme isozyme|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 20|amod|start_entity kinases|nmod|20 kinases|nmod|phosphorylation phosphorylation|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 resulted|nsubj|start_entity resulted|nmod|% %|nmod|men men|acl|achieving achieving|dobj|level level|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 consumption|compound|start_entity increased|nmod|consumption increased|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 ligands|amod|start_entity ligands|amod|15-20-fold 15-20-fold|nmod|coexpression coexpression|nmod|glucocorticoid_receptor glucocorticoid_receptor|appos|end_entity 4.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 optimize|dobj|start_entity dosing|advcl|optimize development|acl|dosing allowed|dobj|development allowed|nsubj|advances advances|nmod|pharmacogenetics pharmacogenetics|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 control|nsubj|start_entity control|dep|have have|dobj|levels levels|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 abolished|nsubj|start_entity blockers|acl:relcl|abolished maintained|nsubj|blockers maintained|dobj|contraction contraction|amod|end_entity 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 insensitivity|amod|start_entity promoted|nsubjpass|insensitivity promoted|nmod|overexpression overexpression|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 analysis|amod|start_entity analysis|nmod|peptide peptide|acl|isolated isolated|nmod|digest digest|nmod|one one|nmod|fragments fragments|acl|derived derived|nmod|nagoya nagoya|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 ionophores|nsubj|start_entity ionophores|dobj|a23187 a23187|acl|stimulated stimulated|nmod|cells cells|acl:relcl|effective effective|nmod|concentration concentration|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 derivative|compound|start_entity derivative|acl|based based|nmod|group group|acl:relcl|use use|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity investigate|dobj|effects was|xcomp|investigate was|parataxis|stimulated stimulated|nmod|presence presence|nmod|antagonist antagonist|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 induction|compound|start_entity induction|acl:relcl|plateau plateau|nsubj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 deposited|dobj|start_entity deposited|advcl|rinse rinse|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 formation|nmod|start_entity abrogated|nsubj|formation derived|ccomp|abrogated derived|nsubj|blocking blocking|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|compound|start_entity controls|dobj|metabolism controls|nmod|receptors receptors|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 formation|amod|start_entity correlated|nmod|formation correlated|nsubj|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 circulating|dobj|start_entity produced|advcl|circulating produced|dep|followed followed|nmod|reduction reduction|nmod|mrna mrna|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 transport|compound|start_entity complement|nmod|transport ability|acl|complement basis|nmod|ability identified|nmod|basis identified|nsubjpass|gene gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 hypoglycemia|amod|start_entity unable|nsubj|hypoglycemia unable|advcl|responsive responsive|xcomp|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 induced|nmod|start_entity activation|acl|induced inhibits|dobj|activation hypothesise|advcl|inhibits hypothesise|ccomp|due due|nmod|inhibition inhibition|nmod|activation activation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 factor|compound|start_entity factor|nsubj|1b 1b|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 release|amod|start_entity promoting|dobj|release promoting|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 microm|nmod|start_entity inhibited|nmod|microm inhibited|dobj|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 adenosine_triphosphate|appos|start_entity one|nmod|adenosine_triphosphate one|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 domains|amod|start_entity identification|nmod|domains identification|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 neurotransmission|amod|start_entity influenced|nsubjpass|neurotransmission influenced|nmod|genes genes|amod|polymorphisms polymorphisms|nmod|dopamine_transporter dopamine_transporter|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 2.000000 0 treatment|compound|start_entity development|nmod|treatment mutant|nmod|development mutant|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 exposure|compound|start_entity riparius|nmod|exposure riparius|dobj|genes genes|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 load|compound|start_entity h|nmod|load cho|dep|h lower|nsubj|cho lower|advcl|downregulated downregulated|nsubj|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 analogue|appos|start_entity effect|nmod|analogue explanation|nmod|effect suggested|nmod|explanation suggested|nsubjpass|presence presence|nmod|action action|nmod|end_entity 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 relation|amod|start_entity caused|nmod|relation caused|advcl|had had|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 chaperone/drug|dobj|start_entity chemical|acl|chaperone/drug rescued|nmod|chemical rescued|nsubjpass|mutants mutants|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 0.000000 0 regulation|amod|start_entity has|nmod|regulation has|nsubj|pathway pathway|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 selectivity|nmod|start_entity account|nmod|selectivity account|nsubj|residues residues|dep|val782 val782|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 suppresses|nsubj|start_entity suppresses|xcomp|fused_toes_homolog fused_toes_homolog|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pd98059|compound|start_entity pd98059|dep|end_entity 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity investigated|dobj|effects investigated|nmod|presence presence|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 expressions|nmod|start_entity synthase|nsubj|expressions synthase|ccomp|detected detected|nsubjpass|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 5.000000 0 2.000000 0 10.000000 0 stimulates|nsubj|start_entity stimulates|dobj|endocytosis endocytosis|nmod|protein protein|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 1.000000 0 0.000000 0 correspond|nmod|start_entity correspond|xcomp|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 coordinate|nmod|start_entity coordinate|dobj|regulation regulation|nmod|mrna mrna|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nmod|constants constants|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 peroxidase|amod|start_entity dismutase|amod|peroxidase levels|dep|dismutase levels|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 glycosyltransferase|nmod:npmod|start_entity genes|amod|glycosyltransferase genes|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 combination|nmod|start_entity treatment|nsubj|combination treatment|nmod|dyslipidaemia dyslipidaemia|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 kidney|nmod|start_entity end_entity|nmod|kidney 0.000000 0 0.000000 0 0.000000 0 4.000000 0 1.000000 0 8.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 action|amod|start_entity aspects|nmod|action addresses|dobj|aspects addresses|nmod|phosphorylation phosphorylation|nmod|neurons neurons|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 excised|nsubjpass|start_entity excised|nmod|glycosylases glycosylases|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 insulin|amod|start_entity showed|nsubj|insulin showed|advcl|lower lower|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 release|compound|start_entity involved|nmod|release involved|nsubjpass|pituitary_adenylate_cyclase-activating_polypeptide pituitary_adenylate_cyclase-activating_polypeptide|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 doses|nmod|start_entity pretreated|nmod|doses cells|acl|pretreated monitoring|nmod|cells monitoring|dobj|magnitude magnitude|nmod|depolarization depolarization|acl|observed observed|nmod|addition addition|nmod|+ +|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 suppressed|nmod|start_entity suppressed|nsubjpass|levels levels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 0.000000 0 26.000000 0 0.000000 0 uptake|nmod|start_entity involved|nmod|uptake protein|acl:relcl|involved protein|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 differentially|compound|start_entity affects|nsubj|differentially affects|dobj|function function|nmod|subtypes subtypes|compound|end_entity 2.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 injection|nmod|start_entity rats|nmod|injection loop|nmod|rats administered|nmod|loop administered|nmod|attempt attempt|acl|simulate simulate|dobj|condition condition|acl:relcl|given given|nsubjpass|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 production|nmod|start_entity resulting|nmod|production induced|xcomp|resulting induced|nsubjpass|end_entity 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 correlated|nsubjpass|start_entity correlated|nmod|levels levels|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 12.000000 0 0.000000 0 1.000000 0 31.000000 0 0.000000 0 tested|nsubj|start_entity tested|ccomp|capable capable|advcl|stimulating stimulating|dobj|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effect|nmod|start_entity inhibited|dobj|effect inhibited|nsubj|capsazepine capsazepine|appos|blocker blocker|compound|end_entity 3.000000 0 0.000000 0 10.000000 0 1.000000 0 0.000000 0 4.000000 0 1.000000 0 3.000000 0 1.000000 0 0.000000 0 action|compound|start_entity transition|nmod|action possibility|nmod|transition supports|dobj|possibility study|acl:relcl|supports conclusion|dep|study conclusion|dep|differentiation differentiation|acl|substrate substrate|nmod|synthesis synthesis|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 biosynthesis|compound|start_entity stimulated|dobj|biosynthesis augmented|advcl|stimulated augmented|nsubj|addition addition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 uptake|compound|start_entity regulators|nmod|uptake shown|xcomp|regulators cytoskeleton|acl:relcl|shown link|nmod|cytoskeleton link|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 markedly|compound|start_entity increased|nsubj|markedly increased|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|compound|start_entity isoforms|nmod|metabolism isoforms|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 antagonists|compound|start_entity used|nsubjpass|antagonists used|advcl|drugs drugs|nmod|patients patients|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 drug|nsubj|start_entity drug|acl:relcl|inhibits inhibits|dobj|receptor receptor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 uptake|nmod|start_entity reducing|dobj|uptake show|xcomp|reducing show|ccomp|reduces reduces|nsubj|binding binding|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 prodrug|amod|start_entity efficacy|nmod|prodrug leucovorin|nmod|efficacy effect|nmod|leucovorin xenografts|nsubj|effect xenografts|nmod|levels levels|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 development|nsubj|start_entity development|advcl|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 status|compound|start_entity indicator|nmod|status validated|nmod|indicator validated|advcl|circulating circulating|dobj|receptor receptor|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 alter|nsubj|start_entity alter|nmod|effects effects|nmod|c c|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 pathway|nmod|start_entity inhibition|nmod|pathway have|nsubj|inhibition have|dobj|effect effect|acl|suggesting suggesting|ccomp|regulates regulates|dobj|upstream upstream|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 8.000000 0 18.000000 0 2.000000 0 2.000000 0 1.000000 0 content|compound|start_entity correlate|nmod|content correlate|nsubj|levels levels|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 13.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 angiotensin_ii|appos|start_entity infusion|nmod|angiotensin_ii effect|nmod|infusion assessed|nsubjpass|effect assessed|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 combination|nmod|start_entity optimizing|dobj|combination factor|acl|optimizing factor|nsubj|modulation modulation|nmod|rhythm rhythm|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 addition|nmod|start_entity blocked|nmod|addition observed|advcl|blocked observed|nsubjpass|level level|nmod|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 studies|nmod|start_entity demonstrated|nsubj|studies represents|advcl|demonstrated end_entity|parataxis|represents 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|nmod|start_entity decreased|nsubj|treatment decreased|nmod|each each|nmod|points points|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 exposure|nmod|start_entity increased|dep|exposure increased|dobj|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 -rsb-|amod|start_entity inhibitors|appos|-rsb- inhibitors|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 2.000000 0 8.000000 0 0.000000 0 0.000000 0 0.000000 0 analogs|amod|start_entity emboss|nmod|analogs emboss|dobj|requirements requirements|nmod|affinity affinity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthase|compound|start_entity induction|nmod|synthase trigger|dobj|induction trigger|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 composition|amod|start_entity regulated|nmod|composition regulated|nsubj|release release|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effect|nmod|start_entity studied|nsubjpass|effect studied|advcl|incubating incubating|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 effects|nmod|start_entity examined|dobj|effects examined|advcl|analyse analyse|dobj|effects effects|nmod|glucocorticoids glucocorticoids|nmod|production production|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 polymorphism|compound|start_entity association|dep|polymorphism association|nmod|gene gene|nmod|sensitivity sensitivity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 mediated|nmod|start_entity indicating|ccomp|mediated infused|xcomp|indicating caused|ccomp|infused caused|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 dimethoxyquinazoline|appos|start_entity blocked|nsubj|dimethoxyquinazoline 4|dep|blocked 4|acl|implicating implicating|dobj|transactivation transactivation|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 induces|nsubj|start_entity induces|dobj|expression expression|nmod|genes genes|acl|involved involved|nmod|growth growth|acl:relcl|lack lack|dobj|pres pres|nmod|mechanism mechanism|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 overload|compound|start_entity available|nsubj|overload influencing|ccomp|available influencing|nsubj|testing testing|nmod|variants variants|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 presence|nmod|start_entity oligomerization|nmod|presence required|nsubjpass|oligomerization required|nmod|activation activation|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 activities|amod|start_entity activities|nmod|mice mice|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptors|compound|start_entity mediated|nmod|receptors mediated|nsubjpass|recruitment recruitment|nmod|mrna mrna|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptor|compound|start_entity isoforms|nmod|receptor isoforms|nmod|subunits subunits|appos|end_entity 0.000000 0 0.000000 0 12.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 inhibits|compound|start_entity inhibits|parataxis|axis axis|nsubj|factor-i factor-i|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 domains|amod|start_entity similarity|nmod|domains related|nmod|similarity related|nmod|chains chains|amod|light light|dep|end_entity 1.000000 0 0.000000 0 5.000000 0 1.000000 0 0.000000 0 9.000000 0 0.000000 0 5.000000 0 3.000000 0 0.000000 0 system|amod|start_entity components|nmod|system two|nmod|components activities|appos|two reduced|nsubjpass|activities reduced|parataxis|greater greater|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 availability|nmod|start_entity enhances|dobj|availability enhances|nsubj|bia_3-202 bia_3-202|appos|inhibitor inhibitor|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibits|nsubj|start_entity inhibits|xcomp|receptor receptor|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 hydroxylase|amod|start_entity reduction|nmod|hydroxylase reduction|nsubj|change change|acl|induced induced|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 kinases|compound|start_entity kinases|dep|e.g. e.g.|appos|end_entity 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 2.000000 0 0.000000 0 brain|nmod|start_entity nachrs|nmod|brain maintained|nmod|nachrs maintained|dobj|end_entity 2.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 kinase|compound|start_entity kinase|acl|containing containing|dobj|sequence sequence|acl|encoded encoded|nmod|gene gene|acl|linked linked|nmod|domain domain|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 related|nmod|start_entity seems|advcl|related seems|nsubj|index index|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 activity|compound|start_entity braf|dobj|activity used|parataxis|braf used|dobj|variants variants|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity depletion|nmod|levels depletion|acl|achieved achieved|nmod|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 absorption|amod|start_entity involved|nmod|absorption expression|acl|involved expression|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 activity|nmod|start_entity role|nmod|activity role|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 element|appos|start_entity identified|nmod|element identified|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 tolerance|compound|start_entity fed|nsubj|tolerance speculate|ccomp|fed speculate|nmod|part part|acl|ascribed ascribed|nmod|level level|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 13.000000 0 0.000000 0 levels|nmod|start_entity necessary|nsubj|levels necessary|nmod|production production|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 formation|amod|start_entity caused|nmod|formation caused|nsubj|incubation incubation|nmod|sections sections|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 decreases|compound|start_entity xanthine|nsubj|decreases xanthine|dobj|adherence adherence|dep|role role|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 assay|nmod|start_entity measure|nsubj|assay measure|dobj|cyclosporin_a cyclosporin_a|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|amod|start_entity blocked|nsubjpass|uptake blocked|nmod|antibody antibody|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 kinase|amod|start_entity dependent|dep|kinase phosphorylation|acl:relcl|dependent phosphorylation|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 combing|nmod|start_entity rearrangement|acl|combing rearrangement|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 9.000000 0 0.000000 0 2.000000 0 0.000000 0 activity|compound|start_entity decrease|nmod|activity related|nmod|decrease related|nsubjpass|decline decline|nmod|response response|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 sensitivity|compound|start_entity predict|dobj|sensitivity predict|nsubj|gene gene|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 prevented|nsubj|start_entity prevented|dobj|end_entity 0.000000 0 6.000000 0 0.000000 0 0.000000 0 7.000000 0 9.000000 0 15.000000 0 0.000000 0 7.000000 0 0.000000 0 concentration|compound|start_entity modulated|nsubjpass|concentration modulated|advcl|limiting limiting|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptor|amod|start_entity encodes|dobj|receptor suggesting|ccomp|encodes conserved|xcomp|suggesting conserved|nsubj|analysis analysis|nmod|sequence sequence|acl|verified verified|ccomp|required required|nmod|niacin niacin|nmod|end_entity 2.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 substances|nmod|start_entity inducible|nmod|substances inducible|nsubj|turnover turnover|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity post-transcriptional|nsubj|effect post-transcriptional|advcl|affected affected|nsubjpass|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 glut5|compound|start_entity that|nmod|glut5 different|nmod|that different|nsubj|pattern pattern|nmod|distribution distribution|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 13.000000 0 2.000000 0 0.000000 0 resulted|nsubj|start_entity resulted|nmod|induction induction|nmod|transcription transcription|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 inhibited|nsubj|start_entity inhibited|nmod|expression expression|acl|caused caused|nmod|end_entity 0.000000 0 7.000000 0 2.000000 0 0.000000 0 1.000000 0 8.000000 0 4.000000 0 0.000000 0 4.000000 0 0.000000 0 start_entity|nmod|expressions expressions|nmod|end_entity 2.000000 0 0.000000 0 2.000000 0 7.000000 0 3.000000 0 29.000000 0 0.000000 0 2.000000 0 5.000000 0 0.000000 0 accumulation|compound|start_entity stimulation|nmod|accumulation participate|nmod|stimulation participate|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 uptake|amod|start_entity mediator|nmod|uptake mediator|nsubj|cotransporter cotransporter|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 using|dobj|start_entity gland|acl|using purified|nmod|gland fraction|acl|purified detected|nmod|fraction detected|nsubjpass|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 presence|nmod|start_entity degraded|nmod|presence degraded|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 ability|nmod|start_entity ability|xcomp|induce induce|nmod|content content|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 capable|nsubj|start_entity capable|advcl|relaxing relaxing|nmod|range range|acl:relcl|bind bind|xcomp|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibited|nsubj|start_entity inhibited|dobj|il-1beta il-1beta|dep|induction induction|nmod|protein protein|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 decreased|nsubj|start_entity decreased|advcl|leading leading|xcomp|hypothesize hypothesize|ccomp|regulating regulating|nsubj|content content|amod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2,3,7,8-tetrachlorodibenzo-p-dioxin|appos|start_entity activation|nmod|2,3,7,8-tetrachlorodibenzo-p-dioxin activation|nmod|receptor receptor|appos|end_entity 4.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 kinase|compound|start_entity kinase|acl|encoded encoded|nmod|end_entity 0.000000 0 0.000000 0 25.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 4.000000 0 toxicity|compound|start_entity cultured|nmod|toxicity cultured|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|dobj|receptors receptors|acl:relcl|targets targets|nsubj|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 action|amod|start_entity mediation|nmod|action subfamily|nmod|mediation roles|nmod|subfamily suggests|dobj|roles barrier|acl:relcl|suggests contributing|nmod|barrier cells|acl|contributing predominantly|nmod|cells predominantly|nsubj|presence presence|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 connected|nmod|start_entity connected|nmod|expression expression|nmod|epidermal_growth_factor_receptor epidermal_growth_factor_receptor|appos|end_entity 0.000000 0 0.000000 0 7.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 inhibitors|dep|start_entity presence|nmod|inhibitors enhanced|nmod|presence enhanced|nsubjpass|accumulation accumulation|acl|-lsb- -lsb-|dobj|vinblastine vinblastine|appos|substrate substrate|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 9.000000 0 0.000000 0 0.000000 0 0.000000 0 blocker|amod|start_entity picrotoxin|appos|blocker had|nsubj|picrotoxin blocked|advcl|had blocked|nmod|expression expression|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 prodrug|amod|start_entity tegafur|appos|prodrug containing|dobj|tegafur using|advcl|containing using|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 results|compound|start_entity addition|nmod|results addition|acl:relcl|appears appears|xcomp|increase increase|advcl|demonstrated demonstrated|csubj|demonstrated demonstrated|nmod|generation generation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 transport|compound|start_entity function|nmod|transport suggests|dobj|function suggests|nsubj|distribution distribution|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 inhibition|compound|start_entity effect|nmod|inhibition lies|nsubj|effect lies|advcl|delaying delaying|dobj|formation formation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|amod|start_entity irrespective|nmod|treatment larger|advmod|irrespective larger|nmod|mice mice|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 -rsb-|compound|start_entity mutation|nmod|-rsb- mutation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 concentration|compound|start_entity increase|nmod|concentration required|nsubjpass|increase determine|ccomp|required determine|nsubj|clones clones|appos|panel panel|nmod|antagonists antagonists|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 start_entity|acl:relcl|expressed expressed|nsubjpass|transporter transporter|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 synthesis|amod|start_entity defect|nmod|synthesis ameliorates|dobj|defect ameliorates|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1173|amod|start_entity phosphorylated|nmod|1173 end_entity|dep|phosphorylated 0.000000 0 0.000000 0 7.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 catabolism|compound|start_entity inhibited|nsubjpass|catabolism shows|advcl|inhibited shows|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 b|compound|start_entity potentiated|nmod|b potentiated|nsubjpass|effect effect|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 metabolism|compound|start_entity responsible|nmod|metabolism genes|amod|responsible expression|nmod|genes induced|dobj|expression induced|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 1.000000 0 0.000000 0 exerts|nsubj|start_entity using|ccomp|exerts inhibition|xcomp|using inhibition|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 alter|nsubj|start_entity alter|dobj|concentrations concentrations|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 affected|nmod|start_entity affected|nsubjpass|levels levels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 13.000000 0 0.000000 0 0.000000 0 32.000000 0 0.000000 0 autoreceptor|amod|start_entity autoreceptor|nsubj|support support|nmod|receptor receptor|nummod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 catabolism|nmod|start_entity catabolism|dep|role role|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 resistance|amod|start_entity associated|nmod|resistance phenotypes|acl|associated expression|nsubj|phenotypes expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 growth_hormone|nmod|start_entity end_entity|advcl|growth_hormone 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 1.000000 0 0.000000 0 9.000000 0 0.000000 0 exposure|nmod|start_entity causes|nsubj|exposure causes|dobj|array array|nmod|toxicities toxicities|nmod|vertebrates vertebrates|ref|which mediated|nsubjpass|which mediated|nmod|activation activation|nmod|aryl_hydrocarbon_receptor aryl_hydrocarbon_receptor|appos|end_entity 2.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 inhibitor|compound|start_entity inhibitor|acl:relcl|acts acts|nmod|receptors receptors|nmod|factor factor|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 incubated|nmod|start_entity cells|acl|incubated reduced|nmod|cells reduced|nsubjpass|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 start_entity|nmod|nr2a nr2a|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 prevented|nmod|start_entity prevented|xcomp|giving giving|nmod|existence existence|nmod|action action|nmod|inhibitors inhibitors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 0.000000 0 absorption|compound|start_entity absorption|acl:relcl|result result|nmod|upregulation upregulation|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 11.000000 0 0.000000 0 4.000000 0 12.000000 0 1.000000 0 diethyldithiocarbamate|appos|start_entity upregulates|nsubj|diethyldithiocarbamate upregulates|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 supplementation|compound|start_entity affects|nsubj|supplementation affects|dobj|production production|nmod|cytokines cytokines|nmod|mice mice|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 analogue|nsubj|start_entity analogue|nmod|capsaicin capsaicin|appos|ingredient ingredient|acl:relcl|activates activates|dobj|channel channel|amod|transient_receptor_potential_vanilloid_type-1 transient_receptor_potential_vanilloid_type-1|dep|end_entity 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 depletion|compound|start_entity aldosterone|nmod|depletion aldosterone|nsubj|enhancement enhancement|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 toxicity|compound|start_entity mediates|dobj|toxicity mediates|advcl|reinforcing reinforcing|dobj|importance importance|nmod|element element|nmod|regulation regulation|nmod|transcription transcription|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 quartiles|nmod|start_entity increases|nmod|quartiles increases|xcomp|implicating implicating|dobj|end_entity 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 downregulates|nsubj|start_entity downregulates|nmod|activation activation|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 content|dep|start_entity content|dep|activity activity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 expressing|dobj|start_entity expressing|advcl|buffering buffering|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 enhanced|nmod|start_entity enhanced|nsubjpass|transcription transcription|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 status|compound|start_entity markers|nmod|status studied|nmod|markers studied|dobj|correlations correlations|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 lymphocytes|dep|start_entity lymphocytes|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 ion|compound|start_entity functions|nmod|ion channel|nsubj|functions superfamily|dep|channel member|dep|superfamily member|nsubj|cystic_fibrosis_transmembrane_conductance_regulator cystic_fibrosis_transmembrane_conductance_regulator|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 15.000000 0 3.000000 0 1.000000 0 effects|compound|start_entity understanding|dobj|effects important|advcl|understanding important|nsubj|variants variants|amod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 deliver|dobj|start_entity deliver|nmod|tissues tissues|nmod|receptor receptor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 activation|compound|start_entity mediated|nmod|activation suggesting|ccomp|mediated levels|acl|suggesting levels|nmod|p53 p53|nmod|noxa noxa|appos|gene gene|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 domain|amod|start_entity domain|acl|contained contained|nmod|protein protein|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 inhibits|nsubj|start_entity inhibits|ccomp|mediated mediated|nsubj|migration migration|nmod|suppression suppression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 preference|nmod|start_entity preference|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 2.000000 0 14.000000 0 0.000000 0 0.000000 0 0.000000 0 influences|nsubj|start_entity influences|dobj|secretion secretion|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 modulator|amod|start_entity modulator|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|dep|inhibitor inhibitor|nmod|phosphatidylinositol phosphatidylinositol|nummod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 14.000000 0 0.000000 0 1.000000 0 0.000000 0 abrogated|nsubj|start_entity abrogated|dobj|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 2.000000 0 4.000000 0 1.000000 0 0.000000 0 0.000000 0 intake|compound|start_entity end_entity|nmod|intake 0.000000 0 0.000000 0 1.000000 0 1.000000 0 2.000000 0 35.000000 0 1.000000 0 0.000000 0 73.000000 0 0.000000 0 administration|amod|start_entity result|nmod|administration result|nmod|levels levels|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 treated|nmod|start_entity treated|nsubjpass|cells cells|appos|null null|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 activity|amod|start_entity due|nsubj|activity due|nmod|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 therapy|compound|start_entity feasible|nsubj|therapy males|acl:relcl|feasible target|nmod|males target|nsubj|end_entity 1.000000 0 0.000000 0 6.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 mg/kg|nmod|start_entity treated|nmod|mg/kg mice|acl|treated ca3|nmod|mice cells|nmod|ca3 cells|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 4.000000 0 1.000000 0 4.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 therapy|compound|start_entity combining|nmod|therapy reaching|advcl|combining induced|advcl|reaching induced|dobj|reductions reductions|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transfer|nmod|start_entity steroidogenesis|appos|transfer step|nmod|steroidogenesis mediates|dobj|step mediates|nmod|outer outer|nmod|membrane membrane|acl:relcl|initiates initiates|nsubj|enzyme enzyme|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 start_entity|nmod|cycles cycles|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 transport|compound|start_entity stimulating|dobj|transport influence|dep|stimulating influence|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 start_entity|appos|agent agent|dep|inhibitor inhibitor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 formation|compound|start_entity stimulation|nmod|formation kinase|nsubj|stimulation kinase|ccomp|leads leads|nmod|inactivation inactivation|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|amod|start_entity sensitivity|nmod|treatment influenced|nmod|sensitivity influenced|nmod|infusion infusion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 interact|nmod|start_entity determine|ccomp|interact determine|nsubj|spectra spectra|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 induce|nsubj|start_entity induce|dobj|expression expression|nmod|cyp2b6 cyp2b6|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 reuptake|compound|start_entity inhibition|nmod|reuptake exhibited|nmod|inhibition exhibited|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 chemotherapy|nmod|start_entity obtained|xcomp|chemotherapy material|acl|obtained using|dobj|material isolated|xcomp|using mrna|acl|isolated examined|nmod|mrna examined|dobj|expression expression|amod|thymidylate_synthase thymidylate_synthase|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 presence|nmod|start_entity flow|nmod|presence was|nmod|flow was|nsubj|effect effect|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 genes|compound|start_entity chose|dobj|genes chose|dobj|kcnn3 kcnn3|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 superfamily|compound|start_entity part|nmod|superfamily part|nsubj|family family|amod|end_entity 0.000000 0 0.000000 0 10.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 vanilloid|dep|start_entity vanilloid|advmod|end_entity 4.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 start_entity|acl|stimulate stimulate|advcl|block block|dobj|release release|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 exclusion|amod|start_entity vitro|nmod|exclusion vitro|nmod|technique technique|nmod|binding binding|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 sensitivity|acl|start_entity inhibited|nsubjpass|sensitivity inhibited|nmod|modulation modulation|nmod|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 element|compound|start_entity element|dep|mice mice|appos|- -|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 phosphatidylcholine|nmod|start_entity composed|nmod|phosphatidylcholine liposomes|acl|composed entrapped|nmod|liposomes end_entity|acl|entrapped 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 concentration|compound|start_entity h|nsubj|concentration h|nmod|administration administration|nmod|formulas formulas|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 restored|nsubj|start_entity restored|dobj|levels levels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 composition|amod|start_entity types|nmod|composition chains|nmod|types subunit|nmod|chains subunit|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|nmod|start_entity contributor|nmod|metabolism contributor|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 1.000000 0 3.000000 0 0.000000 0 2.000000 0 3.000000 0 1.000000 0 metabolism|compound|start_entity demonstrated|dobj|metabolism demonstrated|nmod|knockout knockout|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 promotes|nsubj|start_entity examined|ccomp|promotes examined|advcl|suggested suggested|xcomp|elicit elicit|dobj|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 regulation|compound|start_entity study|dobj|regulation study|nmod|model model|acl:relcl|express express|dobj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 exposure|nmod|start_entity produces|nsubj|exposure produces|nmod|systems systems|acl|acts acts|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 concentrations|compound|start_entity extracellular|dobj|concentrations viewed|xcomp|extracellular viewed|nmod|event event|nmod|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 clearance|nummod|start_entity increases|dobj|clearance increases|nsubj|expression expression|nmod|variant variant|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 administration|amod|start_entity increased|nsubj|administration increased|parataxis|less less|nsubj|concentration concentration|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 convert|nmod|start_entity convert|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 species|compound|start_entity species|amod|due due|xcomp|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 induced|nsubj|start_entity induced|dobj|degradation degradation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 protease|amod|start_entity protease|nmod|family family|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 gene|nmod|start_entity expression|nmod|gene studied|nmod|expression transfected|dep|studied transfected|nmod|constructs constructs|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity treatment|nmod|therapy therapy|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 system|amod|start_entity requires|dobj|system requires|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 production|amod|start_entity unaffected|nsubj|production unaffected|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 exendin|dep|start_entity antagonist|appos|exendin antagonist|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 accompanied|nsubjpass|start_entity accompanied|nmod|down-regulation down-regulation|nmod|atp-binding_cassette_family_transporter-type_a1 atp-binding_cassette_family_transporter-type_a1|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 10.000000 0 3.000000 0 0.000000 0 had|nsubj|start_entity inhibited|advcl|had inhibited|nsubj|addition addition|nmod|4-bromophenacyl_bromide 4-bromophenacyl_bromide|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 3.000000 0 0.000000 0 1.000000 0 0.000000 0 antiport|amod|start_entity antiport|amod|electroneutral electroneutral|nmod:npmod|mediates mediates|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 release|amod|start_entity inhibited|dobj|release inhibited|nsubj|antagonist antagonist|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 levels|compound|start_entity rosiglitazone|nmod|levels rosiglitazone|nmod|relation relation|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 13.000000 0 0.000000 0 outputs|amod|start_entity stimulated|dobj|outputs stimulated|nsubj|administration administration|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 production|compound|start_entity perfused|nsubjpass|production perfused|advcl|increased increased|nsubjpass|concentrations concentrations|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 ingestion|nmod|start_entity was|advcl|ingestion was|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 appears|nsubj|start_entity was|advcl|appears was|xcomp|examine examine|dobj|role role|nmod|receptor receptor|nmod|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 site|amod|start_entity p59fyn|nmod|site mutation|nmod|p59fyn enhanced|nsubj|mutation enhanced|dobj|stimulation stimulation|amod|binding binding|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitor|amod|start_entity monomethyl-l-arginine|appos|inhibitor infection|dep|monomethyl-l-arginine decreased|dobj|infection ineffective|advcl|decreased ineffective|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 tissue|nmod|start_entity treatment|nmod|tissue staining|nmod|treatment co-localization|acl|staining co-localization|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 peroxidase|amod|start_entity superoxide_dismutase|amod|peroxidase superoxide_dismutase|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 5.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 metabolism|compound|start_entity increases|nmod|metabolism increases|nsubj|pathway pathway|acl:relcl|independent independent|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 1.000000 0 extracellular|nmod:poss|start_entity extracellular|dep|signaling signaling|nmod|secretion secretion|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|compound|start_entity patients|nmod|metabolism using|nmod|patients using|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 30.000000 0 0.000000 0 group|amod|start_entity alteration|nmod|group results|nmod|alteration discovered|nmod|results discovered|dobj|inactivation inactivation|nmod|isoform isoform|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|appos|inhibitors inhibitors|nmod|transporters transporters|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 rh123|amod|start_entity accumulation|nmod|rh123 detecting|dobj|accumulation evaluated|advcl|detecting evaluated|nsubjpass|ability ability|nmod|isotetrandrine isotetrandrine|acl|inhibit inhibit|dobj|function function|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 sensor|compound|start_entity developed|nsubjpass|sensor developed|advcl|address address|dobj|role role|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 effects|compound|start_entity involve|nsubj|effects involve|nmod|production production|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 12.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 receptors|compound|start_entity activation|nmod|receptors involves|dobj|activation involves|ccomp|show show|ccomp|thalamus thalamus|nsubj|induction induction|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 ng/dl|nmod|start_entity pg/ml|nmod|ng/dl .0001|dep|pg/ml associated|dep|.0001 associated|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 cytotoxicity|nmod|start_entity associated|nsubjpass|cytotoxicity associated|nmod|inhibition inhibition|appos|up-regulation up-regulation|nmod|bim bim|nummod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibits|nsubj|start_entity inhibits|xcomp|due due|nmod|activation activation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 resistance|appos|start_entity type|dobj|resistance type|nsubj|end_entity 0.000000 0 3.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3-kinase|appos|start_entity inhibitors|nmod|3-kinase use|nmod|inhibitors pathways|dep|use demonstrated|nsubj|pathways demonstrated|dobj|abrogation abrogation|nmod|effect effect|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 monitoring|nmod|start_entity column|nmod|monitoring using|dobj|column analyzed|xcomp|using analyzed|nsubjpass|congeners congeners|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 currents|compound|start_entity potentiation|nmod|currents affect|dobj|potentiation affect|nmod|src src|acl|applied applied|nmod|end_entity 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 depletion|nmod|start_entity activates|nsubj|depletion activates|nmod|activation activation|nmod|stromal_interaction_molecule_1 stromal_interaction_molecule_1|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 stimulated|nsubj|start_entity stimulated|dobj|kinase kinase|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 induces|nsubj|start_entity induces|dobj|formation formation|nmod|forms forms|nmod|complex complex|acl|lacking lacking|xcomp|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity competitive|nsubj|effects competitive|advcl|shifted shifted|nsubjpass|curve curve|nmod|end_entity 0.000000 0 3.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|amod|start_entity attenuates|nsubj|treatment attenuates|dobj|level level|nmod|gene gene|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 actions|nmod|start_entity mediate|dobj|actions mediate|nsubj|subtypes subtypes|nmod|receptor receptor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 provides|nsubj|start_entity provides|dobj|option option|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 kinase|amod|start_entity protein|amod|kinase protein|nmod|kda kda|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 prevented|nsubj|start_entity prevented|nmod|inhibition inhibition|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 receptor|amod|start_entity derived|nmod|receptor icam-1|acl|derived icam-1|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 affect|nsubj|start_entity end_entity|advcl|affect 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 generation|compound|start_entity stimulation|nmod|generation reduced|nsubjpass|stimulation reduced|advcl|somatostatin somatostatin|dobj|forskolin forskolin|acl|+ +|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 tumour_necrosis_factor|amod|start_entity tumour_necrosis_factor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 4.000000 0 2.000000 0 trafficking|compound|start_entity involved|nmod|trafficking involved|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 inhibited|nsubj|start_entity inhibited|advcl|augmented augmented|dobj|production production|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 rats|nmod|start_entity treating|dobj|rats methods|acl|treating using|dobj|methods determined|xcomp|using determined|nsubjpass|activity activity|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 surface|nmod|start_entity analyse|nmod|surface analyse|dobj|organization organization|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 atoms|compound|start_entity bound|nsubjpass|atoms report|parataxis|bound report|ccomp|robust robust|nsubj|capacity capacity|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 2.000000 0 2.000000 0 0.000000 0 pre-treated|nmod|start_entity reversed|advcl|pre-treated reversed|nsubjpass|effects effects|nmod|expression expression|amod|resveratrol resveratrol|nmod|end_entity 6.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 secretion|compound|start_entity effect|nmod|secretion compared|nmod|effect compared|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 fluxes|compound|start_entity altering|dobj|fluxes /|dep|altering /|dep|deleting deleting|advcl|signalling signalling|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 treatment|nmod|start_entity increased|nsubj|treatment increased|nmod|activators activators|compound|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 agonist|amod|start_entity response|nmod|agonist response|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 supplemented|nmod|start_entity diets|acl|supplemented fed|dobj|diets fed|parataxis|provide provide|nmod|pathway pathway|acl|remethylation remethylation|dobj|homocysteine_methyltransferase homocysteine_methyltransferase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 induction|nmod|start_entity correlate|nsubj|induction correlate|advcl|bind bind|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 erbumine|amod|start_entity ester|nsubj|erbumine ester|nmod|perindoprilat perindoprilat|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 16.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity assess|dobj|effects assess|nmod|production production|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 protein|compound|start_entity effects|nmod|protein outside|nmod|effects occurs|dobj|outside occurs|nsubj|effect effect|nmod|secretion secretion|amod|ezetimibe ezetimibe|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 phosphorylation|amod|start_entity inhibits|dobj|phosphorylation inhibits|nsubj|degradation degradation|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 compartments|nmod|start_entity involve|dobj|compartments involve|nsubj|regulation regulation|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 cytochrome_p450_1a1|amod|start_entity cytochrome_p450_1a1|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 0.000000 0 -rsb-|amod|start_entity effect|nmod|-rsb- effect|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 6.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 complex|compound|start_entity component|nmod|complex absence|nmod|component resulted|nsubj|absence resulted|nmod|level level|nmod|activity activity|acl:relcl|comparable comparable|nmod|observed observed|advcl|observed observed|nmod|patient patient|nmod|levels levels|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 increases|amod|start_entity bioactive|nsubj|increases bioactive|advcl|indicating indicating|ccomp|present present|nsubj|pathway pathway|nmod|regulation regulation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 stimulates|advmod|start_entity stimulates|nsubj|gene gene|acl|cells cells|nmod|mechanism mechanism|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 circulating|dobj|start_entity suggested|advcl|circulating suggested|nsubj|nicotinic_acetylcholine_receptor nicotinic_acetylcholine_receptor|appos|end_entity 2.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthesis|amod|start_entity conferring|dobj|synthesis conferring|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 ursodeoxycholic_acid|nmod|start_entity end_entity|nmod|ursodeoxycholic_acid 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibitor|nmod|start_entity modulation|nmod|inhibitor modulation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 sequence|amod|start_entity requiring|dobj|sequence specified|xcomp|requiring specified|nsubjpass|the the|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptor|amod|start_entity up-regulation|nmod|receptor augmenting|dobj|up-regulation 2d3|acl|augmenting half-life|dep|2d3 increased|dobj|half-life increased|nsubj|inhibition inhibition|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 homozygotes|amod|start_entity homozygotes|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 inhibited|nsubj|start_entity resulted|parataxis|inhibited resulted|nmod|superinduction superinduction|nmod|mrna mrna|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 role|nmod|start_entity studied|dobj|role studied|advcl|regulating regulating|nmod|production production|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 production|compound|start_entity capacity|nmod|production retain|dobj|capacity retain|nmod|loss loss|nmod|activity activity|amod|glucose-6-phosphatase glucose-6-phosphatase|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 withdrawal|amod|start_entity block|nmod|withdrawal block|dobj|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 7.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 -|amod|start_entity -|appos|end_entity 1.000000 0 0.000000 0 7.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 2.000000 0 0.000000 0 5.000000 0 auto|amod|start_entity kinase|nmod|auto kinase|nsubj|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 production|amod|start_entity activation|nmod|production extent|nmod|activation causes|nmod|extent causes|nsubj|treatment treatment|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 augmentation|nmod|start_entity augmentation|nmod|production production|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 administration|nmod|start_entity observed|nmod|administration observed|nsubjpass|induction induction|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 start_entity|nsubj|action action|nmod|inhibitor inhibitor|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 capability|nmod|start_entity overcome|dobj|capability overcome|advcl|induced induced|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 species|compound|start_entity expression|nmod|species increased|dobj|expression increased|nmod|upregulation upregulation|nmod|genes genes|appos|mcp-1 mcp-1|dep|klf4 klf4|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 genes|amod|start_entity genes|appos|cyp11b2 cyp11b2|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 dehydrase|amod|start_entity alanine_aminotransferase|appos|dehydrase alanine_aminotransferase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 responsive|amod|start_entity elements|amod|responsive bound|nmod|elements bound|nsubj|complexes complexes|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 pathway|dep|start_entity pathway|compound|end_entity 0.000000 0 2.000000 0 1.000000 0 1.000000 0 3.000000 0 6.000000 0 33.000000 0 1.000000 0 2.000000 0 0.000000 0 suppressed|nmod|start_entity suppressed|nsubjpass|cells cells|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 flowing|nmod|start_entity attenuation|acl|flowing attenuation|nmod|current current|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 reabsorption|compound|start_entity mediated|nmod|reabsorption mediated|nsubj|administration administration|nmod|mice mice|acl|resulted resulted|nmod|decrease decrease|nmod|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 8.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 oxidation|nmod|start_entity catalyzes|dobj|oxidation catalyzes|nsubj|succinic_semialdehyde_dehydrogenase succinic_semialdehyde_dehydrogenase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 monotherapy|nmod|start_entity value|nmod|monotherapy value|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 lps|appos|start_entity subunit|nmod|lps role|nmod|subunit role|dep|responses responses|acl:relcl|mediated mediated|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 lines|compound|start_entity treatment|nmod|lines treatment|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 desaturase|amod|start_entity function|nmod|desaturase gain|nmod|function promoted|dobj|gain promoted|nsubj|1 1|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 concentrations|nmod|start_entity observed|nmod|concentrations observed|nsubjpass|induction induction|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 challenge|compound|start_entity blocks|nmod|challenge blocks|nsubj|pre-treatment pre-treatment|nmod|antagonist antagonist|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 diltiazem|nmod|start_entity coadministration|nmod|diltiazem alter|nsubj|coadministration alter|dobj|metabolism metabolism|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 efflux|compound|start_entity elevated|dobj|efflux elevated|nsubj|apo_a-i apo_a-i|appos|acceptor acceptor|acl|transported transported|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 10.000000 0 3.000000 0 0.000000 0 heifers|nmod|start_entity suppressed|nmod|heifers suppressed|nsubjpass|secretion secretion|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 12.000000 0 2.000000 0 0.000000 0 6.000000 0 0.000000 0 presence|nmod|start_entity essential|nsubj|presence essential|advcl|provoking provoking|dobj|release release|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 function|nummod|start_entity determine|nmod|function represent|advcl|determine represent|nsubj|examination examination|nmod|response response|nmod|agonists agonists|nummod|end_entity 1.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 cytotoxicity|nmod|start_entity mediates|dobj|cytotoxicity molecule|acl:relcl|mediates end_entity|nmod|molecule 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 phosphodiesterase|compound|start_entity inhibitor|nmod|phosphodiesterase cicletanine|nmod|inhibitor restore|nsubj|cicletanine restore|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 interact|nmod|start_entity p56lck|amod|interact p56lck|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 cells|nmod|start_entity treatment|nmod|cells treatment|dep|resulted resulted|nmod|induction induction|nmod|apoptosis apoptosis|nmod|autophosphorylation autophosphorylation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 motifs|compound|start_entity motifs|nmod|structure structure|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 expression|amod|start_entity derived|nsubj|expression derived|nmod|mice mice|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transcription|nmod|start_entity regulation|nmod|transcription involves|nsubj|regulation involves|dobj|induction induction|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|acl|suggesting suggesting|dobj|role role|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 evoked|nsubj|start_entity evoked|nmod|-rsb- -rsb-|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 development|nummod|start_entity end_entity|nmod|development 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 environment|compound|start_entity maintaining|nmod|environment suggests|advcl|maintaining suggests|dobj|role role|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 concentration|compound|start_entity reduction|nmod|concentration suppressed|nsubj|reduction suppressed|advcl|while while|dep|-6 -6|dep|x x|dep|10 10|dep|increase increase|nmod|concentration concentration|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 suppressed|nsubj|start_entity inhibitors|ccomp|suppressed inhibitors|nsubj|end_entity 0.000000 0 2.000000 0 0.000000 0 0.000000 0 10.000000 0 5.000000 0 33.000000 0 0.000000 0 0.000000 0 0.000000 0 deoxyguanosine|dep|start_entity 7|appos|deoxyguanosine paired|nsubjpass|7 duplexes|acl:relcl|paired efficiently|nmod|duplexes acts|advmod|efficiently acts|nsubj|product product|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 kinase|amod|start_entity epidermal_growth_factor_receptor|amod|kinase lung_cancer|nmod|epidermal_growth_factor_receptor inhibitors|amod|lung_cancer sensitivity|nmod|inhibitors associated|nsubjpass|sensitivity associated|nmod|mutations mutations|nmod|domain domain|nmod|end_entity 0.000000 0 0.000000 0 7.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 drinking|compound|start_entity link|nmod|drinking link|nsubj|polymorphism polymorphism|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 actions|nmod|start_entity produced|nmod|actions produced|nmod|receptors receptors|nummod|end_entity 1.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 actions|nmod|start_entity mediates|dobj|actions protein|acl:relcl|mediates protein|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 molecule|compound|start_entity form|nmod|molecule performed|nmod|form performed|nmod|acetylcholinesterase acetylcholinesterase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 synthase|compound|start_entity enzymes|nmod|synthase cofactor|nmod|enzymes glutathione|appos|cofactor deplete|dobj|glutathione end_entity|acl:relcl|deplete 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 anticoagulant|nsubj|start_entity anticoagulant|acl:relcl|bioconverted bioconverted|nmod|form form|appos|ar-h067637 ar-h067637|appos|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 intake|compound|start_entity change|nsubj|intake change|nmod|group group|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 2.000000 0 decarboxylase|amod|start_entity synthesis|nmod|decarboxylase suffered|nmod|synthesis striatum|acl:relcl|suffered striatum|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 arrested|dep|start_entity arrested|advcl|inhibiting inhibiting|dobj|activation activation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 intake|compound|start_entity effect|nmod|intake investigated|dobj|effect investigated|nmod|abundance abundance|nmod|targets targets|nmod|aconitase aconitase|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 status|amod|start_entity improved|nsubj|status improved|nmod|group group|dep|uic uic|dep|microg/l microg/l|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 protein|compound|start_entity region|nmod|protein induced|nmod|region stages|acl|induced protection|nmod|stages degree|nmod|protection degree|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 inhibits|nsubj|start_entity suggesting|ccomp|inhibits increased|xcomp|suggesting increased|parataxis|having having|nmod|binding binding|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 formyl-methionyl-leucylphenylalanine|appos|start_entity inhibited|nmod|formyl-methionyl-leucylphenylalanine inhibited|nsubj|treatment treatment|nmod|neutrophils neutrophils|nmod|antiserum antiserum|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthesis|amod|start_entity reduced|nsubjpass|synthesis reduced|nmod|cells cells|acl|treated treated|nmod|sirna sirna|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 synthetase|compound|start_entity end_entity|appos|synthetase 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 4.000000 0 3.000000 0 alters|dobj|start_entity investigated|advcl|alters investigated|nsubjpass|levels levels|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 15.000000 0 0.000000 0 0.000000 0 14.000000 0 0.000000 0 fed|dobj|start_entity mice|acl|fed effect|dep|mice effect|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 molecules|compound|start_entity appeared|nsubj|molecules appeared|nmod|addition addition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 421-436|compound|start_entity constitute|nsubj|421-436 constitute|dobj|determinant determinant|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nsubj|janus_kinase_2 janus_kinase_2|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 normalized|nmod|start_entity normalized|nsubj|treatment treatment|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 uptake|nmod:npmod|start_entity decreased|dobj|uptake decreased|nsubj|knockdown knockdown|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 dropped|nsubj|start_entity rose|advcl|dropped rose|nsubj|activity activity|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 start_entity|nsubj|dismutase dismutase|appos|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 19.000000 0 28.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 exhaustion|compound|start_entity coincident|nmod|exhaustion coincident|nsubjpass|retention retention|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 functions|compound|start_entity esterification|nmod|functions compromised|nsubjpass|esterification determine|ccomp|compromised studied|advcl|determine studied|ccomp|catalyzed catalyzed|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 analogues|compound|start_entity molecular_target_of_rapamycin|nmod|analogues molecular_target_of_rapamycin|appos|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 5.000000 0 8.000000 0 18.000000 0 2.000000 0 2.000000 0 1.000000 0 trpv6|compound|start_entity trpv6|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 resistant|amod|start_entity cells|amod|resistant have|nsubj|cells have|dobj|levels levels|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 analogue|appos|start_entity respond|nmod|analogue indicating|ccomp|respond data|acl|indicating confirmed|nsubjpass|data confirmed|nmod|studies studies|acl|showing showing|dobj|reduction reduction|nmod|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 reached|nmod|start_entity reached|dep|elicit elicit|dobj|rise rise|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 suppression|appos|start_entity suppression|nmod|end_entity 1.000000 0 1.000000 0 2.000000 0 0.000000 0 3.000000 0 1.000000 0 9.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity assessments|nmod|effects suggest|nsubj|assessments suggest|ccomp|relevant relevant|nsubj|interactions interactions|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|ccomp|showed showed|nsubj|b b|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 transporter|amod|start_entity properties|nmod|transporter analyzed|nsubjpass|properties demonstrate|ccomp|analyzed demonstrate|advcl|using using|advcl|expressing expressing|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 start_entity|acl|mediated mediated|xcomp|reducing reducing|dobj|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|nmod|start_entity decrease|nmod|uptake resulted|nmod|decrease resulted|nsubj|addition addition|appos|inhibitor inhibitor|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 antagonists|amod|start_entity antagonists|appos|inhibitors inhibitors|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 has|nsubj|start_entity fatty_acid|ccomp|has suggest|ccomp|fatty_acid tested|advcl|suggest tested|nsubjpass|effects effects|nmod|cells cells|amod|butyrate butyrate|nmod|translocation translocation|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 relationship|nmod|start_entity has|dobj|relationship has|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 increased|nsubj|start_entity declined|advcl|increased resulted|parataxis|declined resulted|nmod|utilization utilization|nmod|inhibitors inhibitors|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 9.000000 0 0.000000 0 0.000000 0 0.000000 0 increase|nmod|start_entity induced|dobj|increase induced|nsubj|treatment treatment|nmod|ro5-4864 ro5-4864|dep|ligand ligand|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 tetralin|appos|start_entity 8-hydroxy-2|dep|tetralin site|nmod|8-hydroxy-2 have|nmod|site agents|acl:relcl|have inhibited|nsubj|agents inhibited|parataxis|antagonized antagonized|xcomp|consistent consistent|nmod|effects effects|nmod|site site|nummod|end_entity 2.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 gene|compound|start_entity hepcidin|appos|gene regulator|nmod|hepcidin gene|acl:relcl|regulator gene|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 nucleotide_uridine_diphosphate|appos|start_entity responds|nmod|nucleotide_uridine_diphosphate family|acl:relcl|responds member|nmod|family member|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 turnover|nmod|start_entity suggests|dobj|turnover suggests|nsubj|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 phosphate|appos|start_entity ,5|dep|phosphate inhibits|dobj|,5 inhibits|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 channel|compound|start_entity activation|nmod|channel calcium|nmod|activation rise|nmod|calcium stimulates|dobj|rise stimulates|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 receptor|compound|start_entity endocytosis|nmod|receptor sites|appos|endocytosis control|nmod|sites control|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 fever|compound|start_entity remained|nsubj|fever required|parataxis|remained required|xcomp|attenuate attenuate|dobj|fever fever|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 hepcidin|compound|start_entity encoding|dobj|hepcidin gene|acl|encoding end_entity|appos|gene 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 protein|nmod|start_entity transferrin|appos|protein transferrin|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 transients|compound|start_entity elicited|nsubj|transients increased|ccomp|elicited prior|nmod|increased added|advmod|prior observed|ccomp|added observed|nmod|studies studies|nmod|regulation regulation|nmod|transduction transduction|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 30.000000 0 0.000000 0 25-hydroxylase|nsubj|start_entity considered|xcomp|25-hydroxylase used|xcomp|considered cyp27a1|acl:relcl|used compared|nmod|cyp27a1 compared|nsubjpass|metabolism metabolism|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 production|nmod|start_entity stimulates|dobj|production stimulates|nsubj|angiotensin_ii angiotensin_ii|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 antagonists|dobj|start_entity antagonists|parataxis|shifted shifted|nsubj|end_entity 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 induced|nmod|start_entity defects|acl|induced develop|nsubj|defects develop|dobj|assay assay|nmod|inhibition inhibition|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 species|nmod|start_entity species|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 uptake|amod|start_entity uptake|acl|mediated mediated|nmod|transporter-1 transporter-1|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 +|compound|start_entity decreased|nmod|+ decreased|nmod|reconstitution reconstitution|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 replicated|nmod|start_entity replicated|nmod|activation activation|nmod|receptor receptor|compound|end_entity 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 exposure|compound|start_entity changes|nmod|exposure examine|nmod|changes examine|dobj|influence influence|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pathway|amod|start_entity b-catenin|nmod|pathway activate|dobj|b-catenin signaling|advcl|activate egfr|acl|signaling activate|dobj|egfr activate|parataxis|shown shown|xcomp|form form|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity reinforcing|dobj|effects the|dep|reinforcing mediates|dobj|the mediates|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 homeostasis|compound|start_entity study|nmod|homeostasis study|dobj|effect effect|nmod:poss|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 activation|amod|start_entity enzyme|nmod|activation proposed|nmod|enzyme proposed|nsubjpass|paraoxonase-1 paraoxonase-1|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 eg|appos|start_entity inhibitors|dep|eg inhibitors|nummod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 2.000000 0 10.000000 0 0.000000 0 1.000000 0 0.000000 0 have|nmod|start_entity have|dobj|potency potency|nmod|kinase kinase|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 9.000000 0 0.000000 0 2.000000 0 0.000000 0 species|compound|start_entity modulated|nmod|species modulated|nsubjpass|effects effects|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 dehydrogenase|amod|start_entity subunits|nsubj|dehydrogenase genes|dep|subunits genes|appos|sdhd sdhd|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 inhibited|nsubj|start_entity inhibited|dobj|uptake uptake|nmod|l-glutamate l-glutamate|appos|substrate substrate|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 3.000000 0 0.000000 0 1.000000 0 0.000000 0 consumption|compound|start_entity consumption|nmod|ml ml|amod|m-2 m-2|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 synthesized|nsubjpass|start_entity synthesized|nmod|oxygenation oxygenation|nmod|isoforms isoforms|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 uptake|nsubj|start_entity loss|advcl|uptake assessed|advcl|loss assessed|nmod|binding binding|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthase|amod|start_entity regeneration|nmod|synthase role|nmod|regeneration have|dobj|role have|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 cells|nmod|start_entity expression|nmod|cells expression|appos|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 synthases|amod|start_entity expression|nmod|synthases protect|nmod|expression inhibitors|xcomp|protect inhibitors|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 factor|appos|start_entity end_entity|appos|factor 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 effect|amod|start_entity effect|nmod|end_entity 5.000000 0 1.000000 0 2.000000 0 5.000000 0 11.000000 0 109.000000 1 23.000000 0 1.000000 0 27.000000 0 0.000000 0 exposure|compound|start_entity eliminates|nsubj|exposure eliminates|nmod|response response|compound|end_entity 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|appos|inhibitor inhibitor|nmod|enzyme enzyme|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 10.000000 0 0.000000 0 1.000000 0 1.000000 0 synthase|amod|start_entity induction|nmod|synthase potentiates|dobj|induction potentiates|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 activity|compound|start_entity observed|nmod|activity increases|acl|observed higher|nmod|increases higher|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 16.000000 0 2.000000 0 0.000000 0 metabolism|compound|start_entity using|nsubj|metabolism using|dobj|agonists agonists|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 resulted|nmod|start_entity resulted|nmod|correction correction|nmod|defect defect|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|nsubj|552 552|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treated|nmod|start_entity adenocarcinoma|acl|treated exon|dobj|adenocarcinoma gene|acl|exon gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 8.000000 0 0.000000 0 0.000000 0 0.000000 0 loading|dobj|start_entity responsible|advcl|loading end_entity|acl:relcl|responsible 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 0.000000 0 1.000000 0 pge|dep|start_entity pge|nsubj|metabolites metabolites|nmod|stimulation stimulation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 fingers|compound|start_entity fingers|acl:relcl|incorporated incorporated|nmod|production production|nmod|isoforms isoforms|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 interval|nmod|start_entity curve|nmod|interval area|nmod|curve affected|nsubjpass|area affected|parataxis|suggests suggests|nsubj|trend trend|nmod|auctau auctau|nmod|sorafenib-n-oxide sorafenib-n-oxide|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 concentration|compound|start_entity clarify|nmod|concentration clarify|dobj|impact impact|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 presence|nmod|start_entity obtained|nmod|presence obtained|advcl|evaluate evaluate|dobj|role role|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 had|nsubj|start_entity had|parataxis|correlated correlated|nsubjpass|effectiveness effectiveness|nmod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 status|compound|start_entity due|nmod|status due|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 inhibitor|compound|start_entity inhibitor|nmod|efficacy efficacy|nmod|breast_cancer breast_cancer|appos|+ +|compound|end_entity 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 concentrations|nmod|start_entity containing|dobj|concentrations containing|advcl|study study|dobj|regulation regulation|compound|effects effects|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|nmod|activation activation|nmod|receptors receptors|nummod|end_entity 4.000000 0 0.000000 0 17.000000 0 2.000000 0 0.000000 0 2.000000 0 0.000000 0 4.000000 0 1.000000 0 0.000000 0 formation|amod|start_entity catalyzed|nsubjpass|formation catalyzed|nmod|protein_disulfide_isomerase protein_disulfide_isomerase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 flux|compound|start_entity examined|nmod|flux examined|advcl|establish establish|ccomp|mandatory mandatory|nsubj|downregulation downregulation|nmod|release release|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 start_entity|nmod|eeg eeg|appos|release release|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 levels|nmod|start_entity were|nsubj|levels elevated|dep|were elevated|nsubj|gsh gsh|appos|dismutase dismutase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 abscisic_acid|appos|start_entity present|nsubj|abscisic_acid present|nmod|animals animals|acl:relcl|involved involved|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 using|dobj|start_entity using|nmod|inhibitor inhibitor|nmod|activation activation|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 1.000000 0 3.000000 0 1.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 ingredient|compound|start_entity ingredient|acl:relcl|gasified gasified|advcl|earlier earlier|nmod:npmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 capacity|compound|start_entity capacity|appos|hemoglobin hemoglobin|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 catabolism|amod|start_entity catalyzing|nmod|catabolism induced|advcl|catalyzing induced|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 element|amod|start_entity is|nsubj|element is|advcl|suggesting suggesting|ccomp|have have|nsubj|progesterone_receptor progesterone_receptor|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 ca19-9|compound|start_entity ca19-9|appos|carcinoembryonic_antigen carcinoembryonic_antigen|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 administration|nmod|start_entity stimulated|nmod|administration stimulated|nsubjpass|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 actions|nmod|start_entity involved|nmod|actions mechanisms|acl|involved explore|dobj|mechanisms assessed|advcl|explore assessed|nsubjpass|interactions interactions|nmod|receptors receptors|nmod|components components|nmod|system system|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 incorporation|amod|start_entity inhibition|nmod|incorporation inhibition|nmod|-rsb- -rsb-|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 correlated|nsubjpass|start_entity correlated|nmod|activity activity|dep|change change|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 factor-i|compound|start_entity factor-i|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 1.000000 0 3.000000 0 4.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 resistance|amod|start_entity selected|nmod|resistance selected|nsubj|over-expression over-expression|nmod|pi pi|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibition|amod|start_entity related|nmod|inhibition related|nsubjpass|quantification quantification|compound|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 inhibitors|dep|start_entity inhibitors|amod|adherence adherence|nmod|breakpoint_cluster_region-abelson breakpoint_cluster_region-abelson|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 6.000000 0 0.000000 0 1.000000 0 0.000000 0 hydrolysis|compound|start_entity atpase|dep|hydrolysis atpase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 region|compound|start_entity mediated|nmod|region interaction|acl|mediated result|nmod|interaction end_entity|appos|result 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 that|nmod|start_entity mechanism|nmod|that enzyme|nmod|mechanism enzyme|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 provide|advcl|start_entity provide|dobj|basis basis|nmod|inhibition inhibition|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nsubj|cofactor cofactor|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 presence|nmod|start_entity mediated|nmod|presence induce|ccomp|mediated induce|nsubj|cells cells|acl|lacking lacking|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 affinity|nmod|start_entity increase|nmod|affinity fact|dep|increase +|appos|fact presence|nmod|+ shifted|nmod|presence indicated|ccomp|shifted indicated|nsubj|measurements measurements|nmod|dynamics dynamics|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 lowered|dobj|start_entity lowered|advcl|leaving leaving|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 synthesis|amod|start_entity activity|nmod|synthesis examined|dobj|activity examined|advcl|incubated incubated|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 lower|nmod|start_entity lower|nmod|glargine glargine|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 start_entity|amod|vitamin_d3 infusion|nmod|vitamin_d3 antiphosphaturic|nsubj|infusion antiphosphaturic|advcl|administered administered|nmod|amounts amounts|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 drugs|nmod|start_entity suggesting|nsubj|drugs suggesting|ccomp|remains remains|nsubj|signaling signaling|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 displayed|nsubj|start_entity displayed|dobj|affinity affinity|nmod|receptors receptors|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effects|nmod|start_entity studied|dobj|effects studied|nmod|levels levels|nmod|women women|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 activation|nmod|start_entity targeted|nmod|activation targeted|nsubjpass|aryl_hydrocarbon_receptor aryl_hydrocarbon_receptor|appos|end_entity 2.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 adducts|compound|start_entity adducts|nmod|absence absence|nmod|repair repair|nmod|o6-methylguanine_dna_methyltransferase o6-methylguanine_dna_methyltransferase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 concentration|compound|start_entity decreased|dobj|concentration decreased|advcl|resulting resulting|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 polymorphism|nmod|start_entity polymorphism|nmod|generation generation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 signalling|amod|start_entity signalling|nmod|release release|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 effect|nmod|start_entity alter|dobj|effect alter|advcl|receptor receptor|nsubj|peroxisome_proliferator-activated_receptor_gamma peroxisome_proliferator-activated_receptor_gamma|appos|end_entity 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 had|nsubj|start_entity had|advcl|neurons neurons|acl|indicating indicating|dobj|loss loss|nmod|subunits subunits|nummod|end_entity 0.000000 0 1.000000 0 1.000000 0 0.000000 0 1.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 uptake|compound|start_entity reduction|nmod|uptake exhibited|dobj|reduction exhibited|nmod|increases increases|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 suggesting|nsubj|start_entity suggesting|ccomp|detect detect|nsubj|probe probe|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 pathway|amod|start_entity marker|nmod|pathway end_entity|acl:relcl|marker 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nmod|nsclc nsclc|amod|end_entity 0.000000 0 3.000000 0 0.000000 0 1.000000 0 17.000000 0 13.000000 0 37.000000 0 2.000000 0 1.000000 0 0.000000 0 contrast|nmod|start_entity independent|dep|contrast independent|nmod|status status|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 reduce|advcl|start_entity reduce|nmod|patients patients|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity control|dobj|levels control|nsubj|results results|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 protein|compound|start_entity osteocalcin|appos|protein synthesis|nmod|osteocalcin inhibitor|nmod|synthesis inhibitor|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 +|dep|start_entity +|parataxis|+ +|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 modulates|amod|start_entity end_entity|nsubj|modulates 1.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 11.000000 0 2.000000 0 1.000000 0 3.000000 0 0.000000 0 uptake|nmod|start_entity decreased|dobj|uptake caused|parataxis|decreased caused|nmod|cells cells|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 incubation|nmod|start_entity reversed|nsubj|incubation reversed|advcl|suggesting suggesting|ccomp|isoform isoform|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 use|nmod|start_entity safe|nsubj|use safe|nmod|lung_cancer lung_cancer|acl|harboring harboring|dobj|mutation mutation|amod|end_entity 0.000000 0 1.000000 0 0.000000 0 1.000000 0 7.000000 0 3.000000 0 13.000000 0 0.000000 0 1.000000 0 0.000000 0 inhibited|nmod|start_entity inhibited|nsubjpass|activity activity|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 ratio|compound|start_entity higher|nsubj|ratio end_entity|dep|higher 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 effect|compound|start_entity enhanced|dobj|effect end_entity|dep|enhanced 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 phosphorylated|nsubj|start_entity phosphorylated|dobj|domain domain|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 methylation|compound|start_entity keeps|nsubj|methylation keeps|dobj|genes genes|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3h-phosphatidylethanol|nmod|start_entity analysis|amod|3h-phosphatidylethanol production|nmod|analysis measured|nmod|production measured|nsubjpass|activity activity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 substrate|nmod|start_entity omega-1|appos|substrate due|nsubj|omega-1 due|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 phosphorylation|amod|start_entity phosphorylation|nmod|receptor receptor|nmod|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 2.000000 0 phosphorylation|amod|start_entity characterization|nmod|phosphorylation characterization|acl|vitro vitro|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 biosynthesis|amod|start_entity steps|nmod|biosynthesis catalyzes|dobj|steps catalyzes|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 manage|dobj|start_entity manage|advcl|improving improving|dobj|sensitivity sensitivity|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 presence|nmod|start_entity presence|acl:relcl|ferricyanide ferricyanide|nsubj|stimulates stimulates|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 phosphorylation|amod|start_entity role|nmod|phosphorylation enhance|nsubj|role enhance|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 indicator|nmod|start_entity sensitive|nmod|indicator exposure|amod|sensitive 14-fold|dobj|exposure 12|acl|14-fold margin|acl|12 basing|nsubj|margin basing|nmod|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|compound|start_entity difference|nmod|metabolism experience|nmod|difference prompted|nsubj|experience prompted|xcomp|analyse analyse|nmod|frequency frequency|nmod|gene gene|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 19-9|compound|start_entity fragment|appos|19-9 fragment|appos|ferritin ferritin|appos|carcinoembryonic_antigen carcinoembryonic_antigen|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 supplementation|amod|start_entity reduces|nsubj|supplementation reduces|ccomp|assumed assumed|nsubj|risk risk|appos|accounting accounting|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 homeostasis|compound|start_entity maintaining|dobj|homeostasis crucial|advcl|maintaining crucial|nsubj|expression expression|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 158methionine|appos|start_entity associations|nmod|158methionine associations|dep|polymorphism polymorphism|nmod|catechol-o-methyltransferase catechol-o-methyltransferase|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 drugs|amod|start_entity treated|nmod|drugs patients|acl|treated analyzed|nmod|patients analyzed|nmod|gene gene|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 domain|compound|start_entity interfaces|nmod|domain form|nmod|interfaces form|nsubj|molecules molecules|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transporters|compound|start_entity expression|nmod|transporters induced|dobj|expression induced|parataxis|induced induced|nsubjpass|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 20.000000 0 0.000000 0 1.000000 0 r1881|compound|start_entity nm|nmod|r1881 induces|nsubj|nm induces|dobj|association association|nmod|androgen_receptor androgen_receptor|appos|end_entity 1.000000 0 0.000000 0 2.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 differences|nmod|start_entity account|nmod|differences suppression|acl:relcl|account mediated|dobj|suppression mediated|nsubj|pattern pattern|nmod|distribution distribution|nmod|results results|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 methyl_arginine_hydrochloride|appos|start_entity methyl_arginine_hydrochloride|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 residues|amod|start_entity polymorphisms|nmod|residues influence|nsubj|polymorphisms influence|dobj|variation variation|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 suppressed|nsubj|start_entity suppressed|advcl|inhibiting inhibiting|dobj|activation activation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 1.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 analog|compound|start_entity phosphorylation|nmod|analog phosphorylation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 deficiency|appos|start_entity deficiency|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 6.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 therapy|amod|start_entity started|nsubjpass|therapy baseline|dep|started obtained|nmod|baseline obtained|nsubjpass|levels levels|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pharmacokinetics|nmod|start_entity investigated|nmod|pharmacokinetics investigated|dobj|effect effect|nmod|polymorphism polymorphism|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 variants|dep|start_entity variants|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4-hydroxylase|amod|start_entity end_entity|appos|4-hydroxylase 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 blocked|nmod|start_entity increased|parataxis|blocked increased|parataxis|selective selective|nmod|glucocorticoid_receptor glucocorticoid_receptor|appos|end_entity 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 regulates|nsubj|start_entity consistent|dep|regulates regulation|acl:relcl|consistent impaired|dobj|regulation impaired|nsubj|inhibition inhibition|nmod|induction induction|amod|end_entity 0.000000 0 0.000000 0 2.000000 0 1.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|xcomp|facilitate facilitate|dobj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 mt2|compound|start_entity mt2|compound|end_entity 0.000000 0 0.000000 0 19.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 5.000000 0 0.000000 0 1.000000 0 competitive|advcl|start_entity competitive|xcomp|showing showing|nmod|case case|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity examined|dobj|effect examined|advcl|modulate modulate|dobj|consequences consequences|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|compound|start_entity disruption|nmod|metabolism promoting|dobj|disruption regulate|advcl|promoting regulate|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 inhibits|nsubj|start_entity inhibits|ccomp|causing causing|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 alogliptin|appos|start_entity inhibitors|dep|alogliptin inhibitors|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 1.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 observed|nmod|start_entity inhibit|ccomp|observed inhibit|advcl|has has|nsubj|f f|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 difference|nmod|start_entity patients|nmod|difference levels|nmod|patients levels|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 test|compound|start_entity determined|nmod|test determined|nsubjpass|concentrations concentrations|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 0.000000 0 28.000000 0 0.000000 0 cells|nmod|start_entity exposure|nmod|cells led|nsubj|exposure led|nmod|activation activation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 receptor|amod|start_entity binds|nsubj|receptor binds|dobj|end_entity 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity studying|dobj|effect studying|nmod|lipopolysaccharide lipopolysaccharide|acl|induced induced|dobj|expression expression|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|nmod|start_entity microsomal|nsubj|metabolism microsomal|xcomp|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 converting|nmod|start_entity enzyme|acl|converting cyclooxygenase|acl:relcl|enzyme isoform|nmod|cyclooxygenase isoform|nsubj|cyclooxygenase-2 cyclooxygenase-2|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 phosphorylation|nmod|start_entity phosphorylation|nmod|peptide peptide|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 dependence|compound|start_entity risk|nmod|dependence associated|nmod|risk genes|acl:relcl|associated variants|dep|genes variants|nmod|end_entity 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 neurons|compound|start_entity projections|nmod|neurons involved|nsubjpass|projections involved|nmod|both both|nmod|actions actions|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity enhance|dobj|levels enhance|nsubj|antagonism antagonism|nmod|ouabain ouabain|nmod|effects effects|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 6.000000 0 0.000000 0 induced|nmod|start_entity induced|nsubj|effects effects|nmod|stability stability|nmod|protein protein|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 disrupted|nmod|start_entity disrupted|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 concentrations|nmod|start_entity evaluated|nsubjpass|concentrations evaluated|nmod|inhibitors inhibitors|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 test|compound|start_entity test|acl:relcl|measured measured|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 anions|amod|start_entity generation|nmod|anions mediates|nsubj|generation mediates|dobj|effects effects|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 synthase|compound|start_entity requires|nmod|synthase requires|nsubj|s-nitrosation s-nitrosation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 administration|nmod|start_entity increased|nmod|administration increased|nsubj|mrna mrna|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 activity|appos|start_entity had|nsubj|activity inhibited|parataxis|had inhibited|nsubj|antagonists antagonists|compound|end_entity 1.000000 0 2.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 transport|amod|start_entity allows|dobj|transport allows|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1,25|amod|start_entity binding|nmod|1,25 binding|dep|end_entity 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 3.000000 0 0.000000 0 6.000000 0 level|nmod|start_entity determined|dobj|level determined|nmod|rats rats|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 receptors|compound|start_entity pool|nmod|receptors pool|dep|end_entity 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 levels|compound|start_entity leading|nmod|levels is|xcomp|leading is|parataxis|observed observed|ccomp|participates participates|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 have|nsubj|start_entity have|dobj|effect effect|nmod|immunostaining immunostaining|nmod|end_entity 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 activated|nmod|start_entity cation|ccomp|activated cation|nsubj|transient_receptor_potential_vanilloid_1 transient_receptor_potential_vanilloid_1|appos|end_entity 3.000000 0 0.000000 0 10.000000 0 1.000000 0 0.000000 0 4.000000 0 1.000000 0 3.000000 0 1.000000 0 0.000000 0 desaturase|amod|start_entity desaturase|nmod|yeast yeast|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 channels|compound|start_entity kinetics|nmod|channels influenced|nsubjpass|kinetics influenced|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 exposure|amod|start_entity effects|nmod|exposure effects|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 4.000000 0 2.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 enzymes|amod|start_entity consists|nmod|enzymes consists|nsubj|subfamily subfamily|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentration/dose|nmod|start_entity distribution|nmod|concentration/dose compared|nsubjpass|distribution compared|parataxis|treated treated|nmod|benzodiazepines benzodiazepines|appos|patients patients|nmod|drugs drugs|acl:relcl|inhibit inhibit|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 contrast|nmod|start_entity correlates|nmod|contrast correlates|nsubj|increase increase|nmod|surface surface|nmod|lbd lbd|compound|end_entity 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|acl:relcl|included included|dobj|substudy substudy|acl|testing testing|dobj|value value|nmod|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 pretreatment|nmod|start_entity affect|nsubj|pretreatment affect|dobj|induction induction|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 provide|nsubj|start_entity provide|nmod|present present|nmod|cells cells|acl|infected infected|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treated|nmod|start_entity rats|acl|treated measured|nmod|rats measured|nsubjpass|changes changes|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 6.000000 0 0.000000 0 0.000000 0 0.000000 0 depolarizations|appos|start_entity actions|nmod|depolarizations actions|nmod|end_entity 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 oligonucleotides|nmod|start_entity oligonucleotides|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 5.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 start_entity|acl|signaling signaling|nmod|pathobiology pathobiology|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 phosphorylation|amod|start_entity phosphorylation|nmod|tail tail|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 hydroxylase|compound|start_entity antibodies|nmod|hydroxylase visualized|nmod|antibodies nerves|acl|visualized that|nmod|nerves similar|nmod|that similar|nsubj|distribution distribution|nmod|fibres fibres|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 transport|compound|start_entity transport|acl|associated associated|dobj|genes genes|appos|mice mice|amod|caveolin-1_and_scavenger_receptor-bi caveolin-1_and_scavenger_receptor-bi|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 inos|amod|start_entity indicated|nsubj|inos indicated|nmod|tumors tumors|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 analogue|nmod|start_entity inhibitor|nsubj|analogue inhibitor|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 4.000000 0 1.000000 0 9.000000 0 3.000000 0 0.000000 0 2.000000 0 0.000000 0 function|amod|start_entity induce|dobj|function induce|advcl|implicating implicating|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 residues|amod|start_entity residues|nmod|polypeptide polypeptide|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 responsible|nsubj|start_entity responsible|advcl|inducing inducing|dobj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 2.000000 0 0.000000 0 mammary_tumors|acl:relcl|start_entity type|nmod|mammary_tumors studied|nmod|type studied|nsubjpass|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 effects|nmod|start_entity mediating|dobj|effects mediating|nsubj|androgen_receptor androgen_receptor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 senses|nmod|start_entity senses|nsubj|factor factor|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 destabilized|nmod|start_entity destabilized|nsubjpass|mutant mutant|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 effect|compound|start_entity exclude|dobj|effect exclude|nmod|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|amod|start_entity prevents|nsubj|treatment prevents|dobj|formation formation|nmod|activated activated|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|amod|alpha alpha|dep|end_entity 2.000000 0 1.000000 0 44.000000 0 0.000000 0 1.000000 0 29.000000 0 0.000000 0 3.000000 0 1.000000 0 18.000000 0 agonist|amod|start_entity agonist|acl:relcl|suppresses suppresses|dobj|secretion secretion|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 17.000000 0 1.000000 0 0.000000 0 15.000000 0 1.000000 0 confers|nmod|start_entity confers|nsubj|element element|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 exert|nsubj|start_entity exert|advcl|suppressing suppressing|dobj|activation activation|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 decreased|nsubj|start_entity decreased|advcl|increased increased|dobj|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 altered|nsubj|start_entity altered|dobj|concentration concentration|nmod|astrocytes astrocytes|acl:relcl|expressed expressed|dobj|mrna mrna|appos|end_entity 1.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 transport|amod|start_entity inhibition|nmod|transport caused|dobj|inhibition caused|nmod|deficits deficits|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 administration|amod|start_entity given|nmod|administration given|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|nummod|1 1|compound|end_entity 0.000000 0 7.000000 0 2.000000 0 0.000000 0 1.000000 0 8.000000 0 4.000000 0 0.000000 0 4.000000 0 0.000000 0 transport|compound|start_entity associated|nmod|transport associated|nmod|protein protein|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 9.000000 0 2.000000 0 0.000000 0 radiation|compound|start_entity treatment|nmod|radiation foci|nmod|treatment foci|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 having|dobj|start_entity protein|acl|having protein|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 also|dep|start_entity transport|dep|also transport|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 dehydrogenase|amod|start_entity gene|dep|dehydrogenase end_entity|appos|gene 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 leptomycin_b|appos|start_entity using|dobj|leptomycin_b obtained|xcomp|using results|acl|obtained resulting|nmod|results phenotypes|acl|resulting led|nsubj|phenotypes led|advcl|required required|nsubjpass|export export|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 lowering|dobj|start_entity associated|advcl|lowering associated|nsubjpass|administration administration|acl|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 7.000000 0 0.000000 0 activation|amod|start_entity alterations|nmod|activation investigated|nsubjpass|alterations investigated|nmod|field field|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|amod|start_entity effect|nmod|treatment absent|nsubj|effect absent|xcomp|establishing establishing|dobj|role role|nmod|end_entity 4.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 efflux|compound|start_entity promoting|dobj|efflux role|acl|promoting have|dobj|role have|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 10.000000 0 3.000000 0 0.000000 0 status|compound|start_entity decline|nmod|status contribute|nmod|decline zinc|acl:relcl|contribute zinc|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 rate|nmod|start_entity contributions|nmod|rate contributions|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 change|nmod|start_entity change|nsubj|concentrations concentrations|compound|end_entity 0.000000 0 0.000000 0 2.000000 0 1.000000 0 4.000000 0 4.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 phosphorylates|xcomp|start_entity membrane|acl:relcl|phosphorylates translocates|nmod|membrane translocates|nsubj|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 re-uptake|nmod|start_entity terminating|nmod|re-uptake role|acl|terminating has|dobj|role has|nsubj|serotonin_transporter serotonin_transporter|appos|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 signal|nmod|start_entity observed|nsubjpass|signal observed|nmod|animals animals|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 transport|nmod|start_entity facilitated|nsubjpass|transport facilitated|nmod|family family|nmod|glucose_transporters glucose_transporters|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 11.000000 0 1.000000 0 0.000000 0 cyclohexyl_ester|appos|start_entity -rsb-|nsubj|cyclohexyl_ester activity|dep|-rsb- activity|acl:relcl|blocked blocked|nmod|-rsb- -rsb-|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 level|nmod|start_entity regulated|nmod|level regulated|nsubjpass|expression expression|acl|detected detected|nmod|assay assay|acl|using using|dobj|end_entity 0.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 10.000000 0 1.000000 0 6.000000 0 12.000000 0 0.000000 0 na|compound|start_entity encoding|dobj|na encoding|nsubj|mutations mutations|nmod|gene gene|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 rhythm|nmod|start_entity transmitted|nmod|rhythm evidence|dep|transmitted confirm|dobj|evidence confirm|ccomp|determinant determinant|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 active|nmod|start_entity active|nsubj|activity activity|amod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 1.000000 0 21.000000 0 0.000000 0 0.000000 0 0.000000 0 retention|amod|start_entity suggest|nmod|retention suggest|advcl|underscoring underscoring|dobj|potential potential|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 uptake|compound|start_entity limit|dobj|uptake extent|acl:relcl|limit evaluate|dobj|extent evaluate|nsubj|dependence dependence|nmod|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 start_entity|appos|protein protein|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 lower|nsubj|start_entity lower|nmod|group group|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 29.000000 0 0.000000 0 3.000000 0 59.000000 0 0.000000 0 examined|nsubjpass|start_entity examined|nmod|inhibition inhibition|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|amod|start_entity plays|nmod|metabolism plays|nsubj|reductase reductase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 4.000000 0 preference|nmod|start_entity have|nmod|preference appear|xcomp|have end_entity|ccomp|appear 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 activity|compound|start_entity corresponded|nmod|activity corresponded|nsubj|sialylation sialylation|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 1.000000 0 0.000000 0 due|nmod|start_entity decreases|xcomp|due decreases|nmod|cells cells|nummod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 residues|amod|start_entity residues|nmod|domains domains|nmod|protein protein|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 levels|compound|start_entity reduction|nmod|levels associated|nmod|reduction associated|nsubjpass|treatment treatment|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 kinase|amod|start_entity kinase|advcl|similar similar|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 enhanced|nmod|start_entity enhanced|dobj|levels levels|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 treatment|compound|start_entity blunted|nsubj|treatment blunted|dobj|response response|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 responsible|nsubj|start_entity known|ccomp|responsible hypothesized|advcl|known hypothesized|ccomp|trigger trigger|dobj|production production|nmod|inducible_nitric_oxide_synthase inducible_nitric_oxide_synthase|appos|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 5.000000 0 2.000000 0 10.000000 0 tension|compound|start_entity increase|nmod|tension vivo|nmod|increase decreased|nmod|vivo decreased|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 activity|appos|start_entity activity|nmod|alanine_amino_transferase alanine_amino_transferase|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 channel|compound|start_entity involvement|nmod|channel potentiates|dep|involvement potentiates|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 uptake|compound|start_entity uptake|appos|translocation translocation|nmod|expression expression|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 3.000000 0 0.000000 0 action|nmod|start_entity mechanism|nmod|action includes|nsubj|mechanism experienced|parataxis|includes experienced|nsubj|patients patients|acl|treated treated|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 sphingosine-1-phosphate|dep|start_entity sphingosine-1-phosphate|nmod:npmod|synthesizes synthesizes|nummod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 2.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity effect|acl:relcl|correlate correlate|nmod|activity activity|nmod|inhibitors inhibitors|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 metabolism|amod|start_entity correction|nmod|metabolism show|nmod|correction show|nmod|doses doses|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 10.000000 0 0.000000 0 0.000000 0 8.000000 0 0.000000 0 synthesis|compound|start_entity synthesis|acl|coupled coupled|nmod|release release|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 arabidopsis|amod|start_entity arabidopsis|amod|alpha alpha|dep|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 are|nmod|start_entity are|nsubj|differences differences|nmod|mechanisms mechanisms|nmod|down-regulation down-regulation|nmod|end_entity 0.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 endocannabinoids|appos|start_entity endocannabinoids|nmod|inhibitor inhibitor|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 8.000000 0 0.000000 0 0.000000 0 0.000000 0 action|amod|start_entity mediated|nsubjpass|action known|ccomp|mediated seems|advcl|known seems|nsubj|presence presence|nmod|end_entity 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 turnover|nmod|start_entity role|nmod|turnover plays|dobj|role plays|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 10.000000 0 3.000000 0 0.000000 0 -lsb-|compound|start_entity -rsb-|nsubj|-lsb- -rsb-|dobj|phosphorylation phosphorylation|nmod|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 import|dobj|start_entity choline_uptake_transporter|acl|import choline_uptake_transporter|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 infusion|nmod|start_entity micrograms/min|nmod|infusion raised|parataxis|micrograms/min raised|dobj|release release|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 treatment|amod|start_entity involved|nmod|treatment involved|nsubjpass|signaling signaling|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 permeation|nmod|start_entity unrelated|nsubj|permeation unrelated|nmod|activity activity|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 absence|nmod|start_entity exhibited|nmod|absence exhibited|dobj|profiles profiles|acl:relcl|implicated implicated|nmod|source source|nmod|ligands ligands|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 2.000000 0 1.000000 0 3.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 attenuation|acl|start_entity attributed|nsubjpass|attenuation attributed|nmod|depletion depletion|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 synapses|nummod|start_entity function|nmod|synapses function|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 permeates|nsubj|start_entity permeates|ccomp|explains explains|nmod|substrates substrates|acl|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 2.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 compounds|compound|start_entity efficacy|nmod|compounds enhances|dobj|efficacy enhances|nsubj|veliparib veliparib|appos|inhibitor inhibitor|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 corticosteroids|dep|start_entity concentrations|nmod|corticosteroids have|nsubj|concentrations have|dobj|effects effects|nmod|presence presence|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 cycle|compound|start_entity reconstruction|nmod|cycle archive|nmod|reconstruction constitutes|dobj|archive constitutes|nsubj|records records|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 patients|nmod|start_entity sorafenib|nmod|patients assessing|advcl|sorafenib explore|advcl|assessing explore|dobj|utility utility|nmod|measurements measurements|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 cholesterol|appos|start_entity cholesterol|appos|sex_hormone_binding_globulin sex_hormone_binding_globulin|appos|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 concentrations|compound|start_entity increase|dobj|concentrations increase|nsubj|administration administration|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 7.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 level|compound|start_entity remained|nsubj|level remained|nmod|treatment treatment|compound|end_entity 0.000000 0 0.000000 0 1.000000 0 1.000000 0 0.000000 0 28.000000 0 0.000000 0 3.000000 0 58.000000 0 0.000000 0 status|amod|start_entity regulates|nsubj|status regulates|xcomp|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 4.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 generation|nmod|start_entity occurs|nmod|generation occurs|nsubj|induction induction|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 restored|nmod|start_entity restored|xcomp|indicating indicating|ccomp|regulated regulated|nsubjpass|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 induced|nmod|start_entity toxicity|acl|induced alleviated|dobj|toxicity alleviated|nsubj|suppression suppression|nmod|function function|amod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 effect|nmod|start_entity showed|nmod|effect showed|nsubj|cells cells|nmod|activity activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 synthesis|compound|start_entity regulates|dobj|synthesis end_entity|acl:relcl|regulates 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 antagonist|amod|start_entity effects|nmod|antagonist examined|dobj|effects examined|nmod|release release|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 0.000000 0 2.000000 0 0.000000 0 induced|nmod|start_entity vasoconstriction|acl|induced reduced|nsubjpass|vasoconstriction reduced|nmod|strain strain|compound|end_entity 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 sensitivity|compound|start_entity regulator|nmod|sensitivity regulator|nsubj|end_entity 0.000000 0 0.000000 0 1.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 sources|nmod|start_entity sources|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 1.000000 0 0.000000 0 concentrations|compound|start_entity regulate|dobj|concentrations serves|xcomp|regulate activity|acl:relcl|serves activity|compound|end_entity 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 0.000000 0 5.000000 0 0.000000 0 group|amod|start_entity 329-413|nmod|group ci|nmod|329-413 ci|nmod|ci reduced|dobj|ci reduced|nsubjpass|levels levels|nmod|end_entity 0.000000 0 0.000000 0 0.000000 0 0.00