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The 2016 Whole-Cell Modeling Summer School

Karr, Jonathan R; Lluch-Senar, Maria; Serrano, Luis; Carrera, Javier

Whole-cell models that predict phenotype from genotype are needed to advance biology, bioengineering, and medicine. Achieving whole-cell models will require extensive collaboration among modelers, experimentalists, mathematicians, computer scientists, and software engineers. In April 2016, we organized the first Whole-Cell Modeling Summer School to begin to build a whole-cell community by training new researchers. The school created the first whole-cell training materials; trained 21 graduate students, postdoctoral scholars, and faculty; and generated ideas about how to better teach whole-cell modeling. To build a whole-cell modeling community, we plan to continue to organize schools, continue to improve these schools based on the lessons that we learned this year, and initiate an annual workshop and/or online seminar series to facilitate sustained discussion about whole-cell modeling.

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  • Karr, J. R., Takahashi, K. & Funahashi, A. The principles of whole-cell modeling. Curr Opin Microbiol 27, 18–24 (2015).

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  • Macklin, D. N., Ruggero, N. A. & Covert, M. W. The future of whole-cell modeling. Curr Opin Biotechnol 28, 111–115 (2014).

  • Karr, J. R. et al. A whole-cell computational model predicts phenotype from genotype. Cell 150, 389–401 (2012).

  • Waltemath, D. et al. Toward community standards and software for whole-cell modeling. IEEE Trans Biomed Eng 63, 2007–2014 (2016).

  • Karr, J. R., Lluch-Senar, M, Serrano, L & Carrera, J. 2016 Whole-Cell Modeling Summer School (2017).

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