2024-03-28T23:34:34Z
https://zenodo.org/oai2d
oai:zenodo.org:8130631
2023-07-10T14:26:45Z
openaire
user-holoruminant
user-eu
Scully, Sabine
Stafford, Michelle
2023-07-04
<p>Board presented to event attendees of the Teagasc Moorepark Dairy Open Day 2023; "Securing a Sustainable Future". For more information on the open day visit: https://www.teagasc.ie/corporate-events/moorepark-open-day/</p>
https://doi.org/10.5281/zenodo.8130631
oai:zenodo.org:8130631
eng
Zenodo
https://zenodo.org/communities/holoruminant
https://zenodo.org/communities/eu
https://doi.org/10.5281/zenodo.8130630
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
Microbiomes, Sustainability & Health
info:eu-repo/semantics/lecture
oai:zenodo.org:8130270
2023-07-10T14:26:45Z
user-holoruminant
user-eu
Scully, Sabine
Earley, Bernadette
Smith, Paul
Stafford, Michelle
Kenny, David
McAloon, Catherine
Fitzgerald, Ricki
Waters, Sinead
2023-07-04
<p>Summary: </p>
<ul>
<li>Diarrhoea or scour is the most common disease in calves under one month of age. </li>
<li>Calf Diarrhoea has many causes and it may be non-infectious (mainly due to nutrition) or infectious. </li>
<li>Optimal colostrum management is essential for the development of the calf's immune system and supports calf gut health. </li>
<li>A microbiome is a community of microorganisms in a particular environment. </li>
<li>The "HoloRuminant" EU-funded project is investigating the role of microbiomes in developing solutions to reduce early-life diseases including calf diarrhoea. </li>
</ul>
written and published as a part of Teagasc Moorepark Dairy Open Day 2023. For more information about the open day please visit https://www.teagasc.ie/corporate-events/moorepark-open-day/
https://doi.org/10.5281/zenodo.8130270
oai:zenodo.org:8130270
eng
Zenodo
https://zenodo.org/communities/holoruminant
https://zenodo.org/communities/eu
https://doi.org/10.5281/zenodo.8130269
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
Calf health, diarrhea, microbes
Calf Diarrhoea- prevention and the role of microbes
info:eu-repo/semantics/other
oai:zenodo.org:8042924
2023-07-10T10:10:20Z
user-holoruminant
user-eu
H. Yang S. Heirbaut J. Jeyanathan N. De Neve L. Vandaele V. Fievez
2022-02-24
<p>Both ruminal microbial structure and functionality might play a role in inter-individual variation in susceptibility for subacute rumen acidosis (SARA) observed in dairy cows. The aims of this study were to determine whether differences between cows with distinct SARA susceptibility were reflected in distinct (1) ruminal microbial communities, (2) salivary bacterial communities, and (3) fermentative capacity of ruminal microbiota assessed in vitro<em>.</em> To test this hypothesis, rumen samples were collected via an esophageal tube on 21 d postpartum from 38 multiparous Holstein cows, which were classified into 4 groups differing in median and mean time of reticular pH below 6 as well as area under the curve of pH below 6.0. During the 21 d postpartum, all cows within a group fulfilled following criteria: susceptible (S, n = 10; mean or median ≥180 min/d), moderately susceptible (MS, n = 7; 60 min/d < mean time of pH below 6 < 180 min/d, and median time of pH below 6 <180 min/d), moderately unsusceptible (MU, n = 11; 10 min/d < mean < 60 min/d, and median time of pH below 6 ≤30 min/d), or unsusceptible (U, n = 10; median = 0 min/d, and mean <10 min/d). Groups did not differ in total daily dry matter intake nor in total, roughage, or concentrate intake during daily 6-h time intervals. Rumen bacterial α-diversity did not differ among groups, but β-diversity varied and bacterial 16S rRNA gene copy numbers were lower in S compared with U cows. The relative abundance of genera <em>Streptococcus</em>, <em>Sharpea</em>, <em>Prevotellaceae_YAB2003</em>, <em>Succinivibrionaceae_UCG-001</em>, <em>Ruminococcus</em>, and <em>Ruminococcaceae_UCG-001</em> were higher in S compared with U cows. In contrast, <em>Lachnospiraceae_ND3007</em> and <em>Oscillospiraceae_V9D2013</em> were more abundant in U cows. Although pH-associated, inter-animal differences were also observed in the salivary bacteria, common differences in ruminal and salivary bacterial genera were limited. The functionality of the rumen microbiota was evaluated in vitro through exposure of the microbial inoculum of S and U cows to an anaerobic buffer at pH 5.8 and 6.8, in the presence of sterile supernatant of their own and of dry cows' rumen fluid (2 × 2 design). Generally, the S inoculum produced more volatile fatty acids, except at low pH with dry cows' supernatant, where volatile fatty acid production was completely impaired and lactate accumulation was highest. Compared with the microbes of U cows, microbes of S cows showed less fermentative activity in situations with 2 stress factors (low pH and an unfamiliar environment, i.e., rumen fluid supernatant of dry cows).</p>
https://doi.org/10.3168/jds.2021-21115
oai:zenodo.org:8042924
Zenodo
https://zenodo.org/communities/holoruminant
https://zenodo.org/communities/eu
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
Subacute ruminal acidosis phenotypes in periparturient dairy cows differ in ruminal and salivary bacteria and in the in vitro fermentative activity of their ruminal microbiota
info:eu-repo/semantics/article
oai:zenodo.org:8042916
2023-07-10T10:10:15Z
user-holoruminant
user-eu
Hong Yang, Stijn Heirbaut, Xiaoping Jing, Nympha De Neve, Leen Vandaele, Jeyamalar Jeyanathan & Veerle Fievez
2022-10-05
<p>The transition period is a challenging period for high-producing dairy cattle. Cows in early lactation are considered as a group at risk of subacute ruminal acidosis (SARA). Variability in SARA susceptibility in early lactation is hypothesized to be reflected in fecal characteristics such as fecal pH, dry matter content, volatile and odd- and branched-chain fatty acids (VFA and OBCFA, respectively), as well as fecal microbiota. This was investigated with 38 periparturient dairy cows, which were classified into four groups differing in median and mean time of reticular pH below 6 as well as area under the curve of pH below 6. Furthermore, we investigated whether fecal differences were already obvious during a period prior to the SARA risk (prepartum).</p>
https://doi.org/10.1186/s40104-022-00738-8
oai:zenodo.org:8042916
Zenodo
https://zenodo.org/communities/holoruminant
https://zenodo.org/communities/eu
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
Susceptibility of dairy cows to subacute ruminal acidosis is reflected in both prepartum and postpartum bacteria as well as odd- and branched-chain fatty acids in feces
info:eu-repo/semantics/article
oai:zenodo.org:8130607
2023-07-10T14:26:45Z
user-holoruminant
user-eu
Stafford, Michelle
Smith, Paul
Scully, Sabine
Buckley, Frank
Waters, Sinead
Kenny, David
2023-07-04
<p>Summary: </p>
<ul>
<li>The microbiome refers to any organisms such as viruses, bacteria and fungi that live within or on a living host. Examples of microbiome habitats include the skin, body cavities, and mucosal surfaces of respiratory, gastrointestinal, and urogenital tracts. </li>
<li>microbes with the rumen play a key role in the conversion of ingested feed into a source of energy and protein for ruminants. However, enteric methane is produced as a by-product of the microbial fermentation in the rumen. </li>
<li>Understanding the temporal development and colonisation of the rumen of young calves, poses a potential avenue for the development of targeted probiotic and additive treatments aimed at increasing the productivity and sustainability of livestock production. </li>
</ul>
written and published as a part of the open day booklet for Teagasc Moorepark Dairy Open Day 2023. for more information about the open day please visit: https://www.teagasc.ie/corporate-events/moorepark-open-day/
https://doi.org/10.5281/zenodo.8130607
oai:zenodo.org:8130607
eng
Zenodo
https://zenodo.org/communities/holoruminant
https://zenodo.org/communities/eu
https://doi.org/10.5281/zenodo.8130606
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
microbiome, rumen, calf
HoloRuminant- Understanding the rumen microbial colonisation of calves and its impact on performance
info:eu-repo/semantics/other
oai:zenodo.org:6873783
2022-07-21T13:48:42Z
openaire
user-holoruminant
user-eu
EFFAB (European Forum of Farm Animal Breeders)
EAAP (European Federation of Animal Science)
2022-03-30
<p>This project brochure provides an overview of the HoloRuminant project.</p>
<p>The HoloRuminant project will provide new knowledge on the <em>microbiomes</em> of the <em>ruminant holobiont</em> to address the microbiome knowledge challenge for sustainability and resilience whilst fostering innovation. With a <em>multi-omics holistic approach</em>, the HoloRuminant project will determine the connectivity between microbiomes from different body sites, their heritability and their influence on emissions, carbon footprint and phenotypic resilience to changing environmental conditions.</p>
<p> </p>
https://doi.org/10.5281/zenodo.6873783
oai:zenodo.org:6873783
eng
Zenodo
https://zenodo.org/communities/holoruminant
https://zenodo.org/communities/eu
https://doi.org/10.5281/zenodo.6873782
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
microbiome
ruminant
holobiont
multi-omics
HoloRuminant project brochure
info:eu-repo/semantics/conferencePoster
oai:zenodo.org:8130715
2023-07-10T14:26:45Z
user-holoruminant
user-eu
Scully, Sabine
Earley, Bernadette
Waters, Sinead
2022-07-05
<p>Summary: </p>
<ul>
<li>Diarrhoea or scours is the most common disease in calves under one month of age. </li>
<li>Calves with diarrhoea are commonly infected with rotavirus and cryptosporidia, which cannot be treated with antibiotics. </li>
<li>A comprehensive herd health plan is necessary to prevent calf diarrhoea. </li>
<li>Optimized colostrum management supports calf gut health and immune function.</li>
<li>Biosecurity and sanitation procedures are of the utmost importance. </li>
<li>The "HoloRuminant" EU-funded project is investigating the role of microbiomes in developing solutions to reduce early-life diseases such as diarrhoea. </li>
</ul>
this piece was written and published as a part of the public outreach event BEEF 2022 held at Teagasc Grange, Dunsany, Co, Meath, Ireland. For more information on this event visit: https://www.teagasc.ie/corporate-events/beef-open-day/
https://doi.org/10.5281/zenodo.8130715
oai:zenodo.org:8130715
eng
Zenodo
https://zenodo.org/communities/holoruminant
https://zenodo.org/communities/eu
https://doi.org/10.5281/zenodo.8130714
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
Calf health, diarrhea
Calf diarrhoea- prevention is better than cure
info:eu-repo/semantics/other
oai:zenodo.org:6873839
2022-07-21T13:48:42Z
openaire
user-holoruminant
user-eu
EFFAB (European Forum of Farm Animal Breeders)
EAAP (European Federation of Animal Science)
2022-03-30
<p>This project roll-up provides an overview of the HoloRuminant project.</p>
<p>The HoloRuminant project will provide new knowledge on the <em>microbiomes</em> of the <em>ruminant holobiont</em> to address the microbiome knowledge challenge for sustainability and resilience whilst fostering innovation. With a <em>multi-omics holistic approach</em>, the HoloRuminant project will determine the connectivity between microbiomes from different body sites, their heritability and their influence on emissions, carbon footprint and phenotypic resilience to changing environmental conditions.</p>
https://doi.org/10.5281/zenodo.6873839
oai:zenodo.org:6873839
eng
Zenodo
https://zenodo.org/communities/holoruminant
https://zenodo.org/communities/eu
https://doi.org/10.5281/zenodo.6873838
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
microbiome
ruminant
holobiont
multi-omics
HoloRuminant project roll-up
info:eu-repo/semantics/conferencePoster
oai:zenodo.org:6873820
2022-07-21T13:48:42Z
openaire
user-holoruminant
user-eu
EFFAB (European Forum of Farm Animal Breeders)
EAAP (European Federation of Animal Science)
2022-03-30
<p>This project poster provides an overview of the HoloRuminant project.</p>
<p>The HoloRuminant project will provide new knowledge on the <em>microbiomes</em> of the <em>ruminant holobiont</em> to address the microbiome knowledge challenge for sustainability and resilience whilst fostering innovation. With a <em>multi-omics holistic approach</em>, the HoloRuminant project will determine the connectivity between microbiomes from different body sites, their heritability and their influence on emissions, carbon footprint and phenotypic resilience to changing environmental conditions.</p>
https://doi.org/10.5281/zenodo.6873820
oai:zenodo.org:6873820
eng
Zenodo
https://zenodo.org/communities/holoruminant
https://zenodo.org/communities/eu
https://doi.org/10.5281/zenodo.6873819
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
microbiome
ruminant
holobiont
multi-omics
HoloRuminant project poster
info:eu-repo/semantics/conferencePoster
oai:zenodo.org:7304403
2022-11-09T08:02:18Z
openaire
user-holoruminant
user-eu
Scully, Sabine
Smith, Paul E.
Earley, Bernadette
McAloon, Catherine
Waters, Sinead
2022-10-07
<p>To evaluate calf diarrhoea and the subsequent recovery, 51 spring born dairy heifer Holstein (HO; n=29, birth weight 34.7 (SEM 0.69) kg) and Jersey (JE; n=22, BW 25.9 (SEM 0.81) kg) calves were observed from birth (0 days (d)) to weaning (82 (SEM 1.43) d). Calves were fed 8.5% BW of colostrum, from either their dam (n=28) or from 2 or less freshly calved cows (n=23) within 2 hours of birth. Calves were clinically assessed using a modified Wisconsin-Madison health scoring system and 0d, 7d, 21d, weaning and at diarrheal disease manifestation (22 (SEM 0.70) d). Diarrheal disease was determined visually in combination with faecal scores during clinical assessment (score: 0-1=healthy; 2-3=scours). Calves with diarrhoeal disease developed were classified as “scouring” (n=27) an absence of symptoms as “healthy” (n=24) during the pre-weaning period. Data were analysed using the PROC MIXED procedure in SAS (9.4). The model included fixed effects (calf breed, dam breed, disease status, and colostrum source) and random effects (shed and lactation number). The mean day post-birth for scour presentation was 23 (SEM 1.04) d and 22 (SEM 0.88) d for HO and JE calves, respectively. There was no effect of disease incidence (P = 0.61), colostrum source (P = 0.95), dam breed (P = 0.40) or calf breed (P = 0.85) on ADG.</p>
<p> </p>
<p>The work done for this observational study is a part of the EU-funded Holoruminant project, whose aim is to better understand ruminant microbiomes and their roles within the host with relation to health, welfare, and production.</p>
https://doi.org/10.5281/zenodo.7304403
oai:zenodo.org:7304403
eng
Zenodo
https://zenodo.org/communities/holoruminant
https://zenodo.org/communities/eu
https://doi.org/10.5281/zenodo.7304402
info:eu-repo/semantics/openAccess
Creative Commons Attribution 4.0 International
https://creativecommons.org/licenses/by/4.0/legalcode
AVTRW Irish Branch Annual Conference, Teagasc Grange, Dunsany Co. Meath Ireland, 7/10/2022
Calf health, diarrhea
An observational study to assess incidence of dairy calf diarrhea and subsequent recovery
info:eu-repo/semantics/conferencePoster