ENTRY       osa04016                    Pathway
NAME        MAPK signaling pathway - plant - Oryza sativa japonica (Japanese rice) (RefSeq)
DESCRIPTION Mitogen-activated protein kinase (MAPK) cascades, the evolutionarily conserved signaling modules in all eukaryotes, serve in transducing extracellular signals to the nucleus or cytoplasm for appropriate cellular responses, including cell division, differentiation, programmed cell death, and adaption to various stresses. In plant, several cascades are triggered by different biotic and abiotic stress stimuli such as pathogen infection, wounding, low temperature, drought, osmotic shock, high salinity, and reactive oxygen species. MAPK pathways also play pivotal roles in processes such as hormonal and developmental signaling. Multiple functional pathways initiated from distinct receptors often share the same kinase components while maintaining their signaling specificity. In contrast to those of animals and fungi, all the plant MAPK genes that have been reported belong to extracellular signal-regulated kinase (ERK) subfamily.
CLASS       Environmental Information Processing; Signal transduction
PATHWAY_MAP osa04016  MAPK signaling pathway - plant
DBLINKS     GO: 0000165
ORGANISM    Oryza sativa japonica (Japanese rice) (RefSeq) [GN:osa]
GENE        4337016  LRR receptor-like serine/threonine-protein kinase FLS2 [KO:K13420] [EC:2.7.11.1]
            4332325  mitogen-activated protein kinase kinase kinase 1 [KO:K13414] [EC:2.7.11.25]
            4333845  mitogen-activated protein kinase kinase kinase 1 [KO:K13414] [EC:2.7.11.25]
            4340126  mitogen-activated protein kinase kinase 2 [KO:K20603] [EC:2.7.12.2]
            4344698  mitogen-activated protein kinase 2 [KO:K20600] [EC:2.7.11.24]
            107278628  protein MKS1-like [KO:K20725]
            9268987  translation initiation factor IF-2 [KO:K20725]
            9268455  protein MKS1 [KO:K20725]
            4327518  probable WRKY transcription factor 33 [KO:K13424]
            4338474  probable WRKY transcription factor 26 isoform X1 [KO:K13424]
            4339092  probable WRKY transcription factor 33 [KO:K13424]
            4330957  mitogen-activated protein kinase kinase 5 [KO:K13413] [EC:2.7.12.2]
            4340367  mitogen-activated protein kinase kinase 5 [KO:K13413] [EC:2.7.12.2]
            4340368  mitogen-activated protein kinase kinase 5 [KO:K13413] [EC:2.7.12.2]
            4332475  mitogen-activated protein kinase 5 isoform X2 [KO:K20536] [EC:2.7.11.24]
            4340170  mitogen-activated protein kinase 1 [KO:K14512] [EC:2.7.11.24]
            4349849  transcription factor VIP1 [KO:K20557]
            4351576  transcription factor VIP1 [KO:K20557]
            4342314  pathogenesis-related protein PRB1-3 [KO:K13449]
            4325422  pathogenesis-related protein 1 [KO:K13449]
            4342317  pathogenesis-related protein PRB1-3 [KO:K13449]
            4348237  pathogenesis-related protein PRB1-2 [KO:K13449]
            107278128  pathogenesis-related protein PRB1-3-like [KO:K13449]
            107278129  pathogenesis-related protein PRB1-3-like [KO:K13449]
            107277171  pathogenesis-related protein PRB1-2-like [KO:K13449]
            4325424  pathogenesis-related protein PRB1-2 [KO:K13449]
            4342318  pathogenesis-related protein 1 [KO:K13449]
            107275384  pathogenesis-related protein PRB1-3-like [KO:K13449]
            107275413  pathogenesis-related protein 1-like [KO:K13449]
            107275753  pathogenesis-related protein 1A-like [KO:K13449]
            107276458  pathogenesis-related protein PRB1-3-like [KO:K13449]
            107276764  pathogenesis-related protein PRB1-3-like [KO:K13449]
            107277316  pathogenesis-related protein 1-like [KO:K13449]
            107281807  pathogenesis-related protein PRMS-like [KO:K13449]
            4342310  pathogenesis-related protein 1 [KO:K13449]
            9270927  pathogenesis-related protein 1 [KO:K13449]
            107277170  pathogenesis-related protein PRB1-2-like [KO:K13449]
            9268689  pathogenesis-related protein PRB1-2 [KO:K13449]
            4342316  pathogenesis-related protein PRB1-2 [KO:K13449]
            4342311  pathogenesis-related protein PRB1-3 [KO:K13449]
            4342313  pathogenesis-related protein PRB1-2 [KO:K13449]
            4342315  pathogenesis-related protein PRB1-2 [KO:K13449]
            4326683  WRKY transcription factor 22 [KO:K13425]
            9267508  WRKY transcription factor 22 [KO:K13425]
            4336750  1-aminocyclopropane-1-carboxylate synthase [KO:K20772] [EC:4.4.1.14]
            4336231  serine/threonine-protein kinase OXI1 [KO:K20714] [EC:2.7.11.1]
            4329907  serine/threonine-protein kinase OXI1 [KO:K20714] [EC:2.7.11.1]
            4339815  nucleoside diphosphate kinase 3 [KO:K00940] [EC:2.7.4.6]
            4343275  nucleoside diphosphate kinase 1 [KO:K00940] [EC:2.7.4.6]
            4352460  nucleoside diphosphate kinase 2, chloroplastic [KO:K00940] [EC:2.7.4.6]
            4349403  nucleoside diphosphate kinase 1 [KO:K00940] [EC:2.7.4.6]
            4345595  mitogen-activated protein kinase kinase kinase NPK1 [KO:K20606] [EC:2.7.11.25]
            9267453  mitogen-activated protein kinase kinase 3 isoform X1 [KO:K20607] [EC:2.7.12.2]
            4328297  mitogen-activated protein kinase 3 [KO:K20535] [EC:2.7.11.24]
            4341956  mitogen-activated protein kinase 4 [KO:K20535] [EC:2.7.11.24]
            4331174  ethylene receptor 3 isoform X1 [KO:K14509] [EC:2.7.13.-]
            4333832  probable ethylene response sensor 1 [KO:K14509] [EC:2.7.13.-]
            4335058  ethylene receptor 2 [KO:K14509] [EC:2.7.13.-]
            4337850  probable ethylene response sensor 2 isoform X1 [KO:K14509] [EC:2.7.13.-]
            4342865  ethylene receptor 4 [KO:K14509] [EC:2.7.13.-]
            4329527  serine/threonine-protein kinase CTR1 isoform X1 [KO:K14510] [EC:2.7.11.1]
            9270313  serine/threonine-protein kinase CTR1 [KO:K14510] [EC:2.7.11.1]
            4334443  protein RTE1-HOMOLOG [KO:K20726]
            4339461  protein REVERSION-TO-ETHYLENE SENSITIVITY1 [KO:K20726]
            4325934  protein REVERSION-TO-ETHYLENE SENSITIVITY1 [KO:K20726]
            4328616  probable copper-transporting ATPase HMA5 [KO:K17686] [EC:7.2.2.8]
            4328448  copper-transporting ATPase RAN1 isoform X1 [KO:K17686] [EC:7.2.2.8]
            4336625  probable copper-transporting ATPase HMA5 [KO:K17686] [EC:7.2.2.8]
            4341778  copper-transporting ATPase RAN1 [KO:K17686] [EC:7.2.2.8]
            4345883  copper-transporting ATPase PAA1, chloroplastic isoform X1 [KO:K17686] [EC:7.2.2.8]
            4331814  copper-transporting ATPase PAA2, chloroplastic isoform X1 [KO:K17686] [EC:7.2.2.8]
            107277074  mitogen-activated protein kinase kinase 9-like [KO:K20604] [EC:2.7.12.2]
            4332115  mitogen-activated protein kinase kinase 9 [KO:K20604] [EC:2.7.12.2]
            4332697  ETHYLENE INSENSITIVE 3-like 1 protein [KO:K14514]
            4344331  ETHYLENE INSENSITIVE 3-like 1 protein [KO:K14514]
            4345992  ETHYLENE INSENSITIVE 3-like 3 protein [KO:K14514]
            4347439  ETHYLENE INSENSITIVE 3-like 3 protein [KO:K14514]
            107276358  ETHYLENE INSENSITIVE 3-like 1 protein [KO:K14514]
            107278750  ETHYLENE INSENSITIVE 3-like 5 protein [KO:K14514]
            4329746  putative ETHYLENE INSENSITIVE 3-like 4 protein [KO:K14514]
            4342431  ethylene-insensitive protein 2 [KO:K14513]
            4333824  ethylene-insensitive protein 2 isoform X1 [KO:K14513]
            4328647  EIN3-binding F-box protein 1 isoform X1 [KO:K14515]
            4341476  EIN3-binding F-box protein 1 [KO:K14515]
            4334408  5'-3' exoribonuclease 4 [KO:K20553] [EC:3.1.13.-]
            4334864  ethylene-responsive transcription factor 15 [KO:K14516]
            9266123  ethylene-responsive transcription factor 1B [KO:K14516]
            4338718  chitinase 2 [KO:K20547] [EC:3.2.1.14]
            4342115  chitinase 1 [KO:K20547] [EC:3.2.1.14]
            4342114  chitinase 3 [KO:K20547] [EC:3.2.1.14]
            4333121  chitinase 12 [KO:K20547] [EC:3.2.1.14]
            4331519  chitinase 11 [KO:K20547] [EC:3.2.1.14]
            4338720  chitinase 7 [KO:K20547] [EC:3.2.1.14]
            4338719  chitinase 9 [KO:K20547] [EC:3.2.1.14]
            4349267  chitinase 8 [KO:K20547] [EC:3.2.1.14]
            4349484  transcription factor MYC2 [KO:K13422]
            4328916  abscisic acid receptor PYL8 isoform X1 [KO:K14496]
            4332548  abscisic acid receptor PYL4 [KO:K14496]
            4338104  abscisic acid receptor PYL8 [KO:K14496]
            4339083  abscisic acid receptor PYL4 [KO:K14496]
            4341193  abscisic acid receptor PYL8 isoform X1 [KO:K14496]
            4341194  abscisic acid receptor PYL8 [KO:K14496]
            4341308  abscisic acid receptor PYL2 [KO:K14496]
            4349472  abscisic acid receptor PYR1 [KO:K14496]
            9270643  abscisic acid receptor PYL2 [KO:K14496]
            107276790  abscisic acid receptor PYL9-like isoform X1 [KO:K14496]
            107276820  abscisic acid receptor PYL4-like [KO:K14496]
            9272602  abscisic acid receptor PYL8 isoform X1 [KO:K14496]
            4324182  probable protein phosphatase 2C 8 [KO:K14497] [EC:3.1.3.16]
            4324201  probable protein phosphatase 2C 6 isoform X1 [KO:K14497] [EC:3.1.3.16]
            4327465  probable protein phosphatase 2C 9 [KO:K14497] [EC:3.1.3.16]
            4332374  probable protein phosphatase 2C 30 [KO:K14497] [EC:3.1.3.16]
            4339454  probable protein phosphatase 2C 50 [KO:K14497] [EC:3.1.3.16]
            4339671  probable protein phosphatase 2C 51 isoform X2 [KO:K14497] [EC:3.1.3.16]
            4339797  probable protein phosphatase 2C 53 [KO:K14497] [EC:3.1.3.16]
            4346736  probable protein phosphatase 2C 68 [KO:K14497] [EC:3.1.3.16]
            9268838  LOW QUALITY PROTEIN: probable protein phosphatase 2C 37 [KO:K14497] [EC:3.1.3.16]
            9270549  probable protein phosphatase 2C 49 [KO:K14497] [EC:3.1.3.16]
            4324934  serine/threonine-protein kinase SAPK4 [KO:K14498] [EC:2.7.11.1]
            4329630  serine/threonine-protein kinase SAPK6 [KO:K14498] [EC:2.7.11.1]
            4333017  serine/threonine-protein kinase SAPK1 isoform X1 [KO:K14498] [EC:2.7.11.1]
            4333435  serine/threonine-protein kinase SAPK10 isoform X2 [KO:K14498] [EC:2.7.11.1]
            4334218  serine/threonine-protein kinase SAPK8 [KO:K14498] [EC:2.7.11.1]
            4335877  serine/threonine-protein kinase SAPK7 [KO:K14498] [EC:2.7.11.1]
            4337502  serine/threonine-protein kinase SAPK5 [KO:K14498] [EC:2.7.11.1]
            4343944  serine/threonine-protein kinase SAPK2 isoform X1 [KO:K14498] [EC:2.7.11.1]
            4349411  serine/threonine-protein kinase SAPK3 [KO:K14498] [EC:2.7.11.1]
            4352660  serine/threonine-protein kinase SAPK9 [KO:K14498] [EC:2.7.11.1]
            4339496  mitogen-activated protein kinase kinase kinase ANP1 [KO:K20716]
            4328073  catalase isozyme A [KO:K03781] [EC:1.11.1.6]
            4342124  catalase isozyme B [KO:K03781] [EC:1.11.1.6]
            4331509  catalase-1 [KO:K03781] [EC:1.11.1.6]
            4326903  calmodulin-3 [KO:K02183]
            4339172  calmodulin-2 [KO:K02183]
            4324384  calmodulin [KO:K02183]
            4334072  calmodulin-like protein 4 [KO:K02183]
            4327351  calmodulin-like protein 1 [KO:K02183]
            4332664  calmodulin [KO:K02183]
            107276719  putative calmodulin-like protein 6 [KO:K02183]
            4339171  probable calcium-binding protein CML9 [KO:K02183]
            4349699  putative calmodulin-like protein 2 isoform X1 [KO:K02183]
            4351420  calmodulin-like protein 3 isoform X1 [KO:K02183]
            4339397  respiratory burst oxidase homolog protein A [KO:K13447] [EC:1.6.3.- 1.11.1.-]
            4326027  respiratory burst oxidase homolog protein B [KO:K13447] [EC:1.6.3.- 1.11.1.-]
            4347158  respiratory burst oxidase homolog protein E [KO:K13447] [EC:1.6.3.- 1.11.1.-]
            4345742  respiratory burst oxidase homolog protein E [KO:K13447] [EC:1.6.3.- 1.11.1.-]
            4324163  respiratory burst oxidase homolog protein A [KO:K13447] [EC:1.6.3.- 1.11.1.-]
            107278041  respiratory burst oxidase homolog protein B-like [KO:K13447] [EC:1.6.3.- 1.11.1.-]
            4352439  respiratory burst oxidase homolog protein B [KO:K13447] [EC:1.6.3.- 1.11.1.-]
            107275690  EPIDERMAL PATTERNING FACTOR-like protein 6 [KO:K20729]
            9271431  protein EPIDERMAL PATTERNING FACTOR 2 [KO:K20729]
            4330905  LRR receptor-like serine/threonine-protein kinase ERECTA isoform X1 [KO:K20718] [EC:2.7.11.1]
            4340000  LRR receptor-like serine/threonine-protein kinase ERL1 [KO:K20718] [EC:2.7.11.1]
            4340427  LRR receptor-like serine/threonine-protein kinase ERECTA [KO:K20718] [EC:2.7.11.1]
            4330249  mitogen-activated protein kinase kinase kinase YODA [KO:K20717] [EC:2.7.11.25]
            4336647  mitogen-activated protein kinase kinase kinase YODA [KO:K20717] [EC:2.7.11.25]
            107276250  transcription factor MUTE-like [KO:K20558]
            9268477  transcription factor SPEECHLESS [KO:K20558]
REFERENCE   PMID:11875555
  AUTHORS   Asai T, Tena G, Plotnikova J, Willmann MR, Chiu WL, Gomez-Gomez L, Boller T, Ausubel FM, Sheen J
  TITLE     MAP kinase signalling cascade in Arabidopsis innate immunity.
  JOURNAL   Nature 415:977-83 (2002)
            DOI:10.1038/415977a
REFERENCE   PMID:12119167
  AUTHORS   
  TITLE     Mitogen-activated protein kinase cascades in plants: a new nomenclature.
  JOURNAL   Trends Plant Sci 7:301-8 (2002)
            DOI:10.1016/S1360-1385(02)02302-6
REFERENCE   PMID:18570633
  AUTHORS   Colcombet J, Hirt H
  TITLE     Arabidopsis MAPKs: a complex signalling network involved in multiple biological processes.
  JOURNAL   Biochem J 413:217-26 (2008)
            DOI:10.1042/BJ20080625
REFERENCE   PMID:18692429
  AUTHORS   Kendrick MD, Chang C
  TITLE     Ethylene signaling: new levels of complexity and regulation.
  JOURNAL   Curr Opin Plant Biol 11:479-85 (2008)
            DOI:10.1016/j.pbi.2008.06.011
REFERENCE   PMID:20441529
  AUTHORS   Rodriguez MC, Petersen M, Mundy J
  TITLE     Mitogen-activated protein kinase signaling in plants.
  JOURNAL   Annu Rev Plant Biol 61:621-49 (2010)
            DOI:10.1146/annurev-arplant-042809-112252
REFERENCE   PMID:20980831
  AUTHORS   Taj G, Agarwal P, Grant M, Kumar A
  TITLE     MAPK machinery in plants: recognition and response to different stresses through multiple signal transduction pathways.
  JOURNAL   Plant Signal Behav 5:1370-8 (2010)
            DOI:10.4161/psb.5.11.13020
REFERENCE   PMID:23263767
  AUTHORS   Meng X, Wang H, He Y, Liu Y, Walker JC, Torii KU, Zhang S
  TITLE     A MAPK cascade downstream of ERECTA receptor-like protein kinase regulates Arabidopsis inflorescence architecture by promoting localized cell proliferation.
  JOURNAL   Plant Cell 24:4948-60 (2012)
            DOI:10.1105/tpc.112.104695
REFERENCE   PMID:25720833
  AUTHORS   Danquah A, de Zelicourt A, Boudsocq M, Neubauer J, Frei Dit Frey N, Leonhardt N, Pateyron S, Gwinner F, Tamby JP, Ortiz-Masia D, Marcote MJ, Hirt H, Colcombet J
  TITLE     Identification and characterization of an ABA-activated MAP kinase cascade in Arabidopsis thaliana.
  JOURNAL   Plant J 82:232-44 (2015)
            DOI:10.1111/tpj.12808
KO_PATHWAY  ko04016
///
