ENTRY       osa00944                    Pathway
NAME        Flavone and flavonol biosynthesis - Oryza sativa japonica (Japanese rice) (RefSeq)
DESCRIPTION Flavones and flavonols (3-hydroxyflavones) are common flavonoids in the plant kingdom. They are synthesized as part of the flavonoid modification pathways in aglycone and glucoside forms.
CLASS       Metabolism; Biosynthesis of other secondary metabolites
PATHWAY_MAP osa00944  Flavone and flavonol biosynthesis
ORGANISM    Oryza sativa japonica (Japanese rice) (RefSeq) [GN:osa]
GENE        4332919  flavonoid 3',5'-hydroxylase 1 [KO:K13083] [EC:1.14.14.81]
            4348304  flavonoid 3'-monooxygenase [KO:K05280] [EC:1.14.14.82]
            4348299  flavonoid 3'-monooxygenase [KO:K05280] [EC:1.14.14.82]
            4326220  UDP-glycosyltransferase 73C6 [KO:K22771] [EC:2.4.1.-]
            4326219  UDP-glycosyltransferase 73C6 [KO:K22771] [EC:2.4.1.-]
            107277497  UDP-glycosyltransferase 73C6-like [KO:K22771] [EC:2.4.1.-]
            4326218  UDP-glycosyltransferase 73C6 [KO:K22771] [EC:2.4.1.-]
            4336438  UDP-glycosyltransferase 73C6 [KO:K22771] [EC:2.4.1.-]
            9267603  anthocyanidin 3-O-glucosyltransferase [KO:K22772] [EC:2.4.1.159]
            4350462  anthocyanidin 3-O-glucosyltransferase [KO:K22772] [EC:2.4.1.159]
COMPOUND    C00389  Quercetin
            C00616  Quercetin 3-sulfate
            C01155  Quercetin 3,3'-bissulfate
            C01156  Quercetin 3,4'-bissulfate
            C01265  3,7-Di-O-methylquercetin
            C01460  Vitexin
            C01470  Acacetin
            C01477  Apigenin
            C01514  Luteolin
            C01714  Isovitexin
            C01750  Quercitrin
            C03515  Luteolin 7-O-glucuronide
            C03897  Quercetin 3,3',7-trissulfate
            C03898  Quercetin 3,4',7-trissulfate
            C03951  Luteolin 7-O-beta-D-glucoside
            C04024  Vitexin 2''-O-beta-D-glucoside
            C04199  Isovitexin 2''-O-beta-D-glucoside
            C04293  Chrysoeriol
            C04443  3-O-Methylquercetin
            C04444  3,7,4'-Tri-O-methylquercetin
            C04608  Apigenin 7-O-beta-D-glucoside
            C04858  Apigenin 7-O-[beta-D-apiosyl-(1->2)-beta-D-glucoside]
            C04900  Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]-4'-O-beta-D-glucuronide
            C05622  Malonylapiin
            C05623  Isoquercitrin
            C05625  Rutin
            C05903  Kaempferol
            C10098  Kaempferide
            C10107  Myricetin
            C10175  Quercetin 3-(2G-xylosylrutinoside)
            C11620  Syringetin
            C12249  Kaempferol 3-O-glucoside
            C12626  Kaempferol-3-O-galactoside
            C12627  Apigenin 7-O-neohesperidoside
            C12628  Vitexin 2''-O-beta-L-rhamnoside
            C12629  Isoswertisin 2''-rhamnoside
            C12630  Scolymoside
            C12632  Luteolin 7-O-[beta-D-glucuronosyl-(1->2)-beta-D-glucuronide]
            C12633  Laricitrin
            C12634  Kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside
            C12635  Kaempferol 3-sophorotrioside
            C12636  Kaempferol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside]
            C12637  Quercetin 3-O-[beta-D-xylosyl-(1->2)-beta-D-glucoside]
            C12638  Quercetin 3-O-(6-O-malonyl-beta-D-glucoside)
            C12667  Quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside
            C12668  Quercetin 3-sophorotrioside
            C16490  Kaempferol 3-O-beta-D-glucosylgalactoside
            C16911  Afzelin
            C19796  Quercetin 3-O-rhamnoside 7-O-glucoside
            C21833  Kaempferol-3-O-rutinoside
            C21854  Kaempferol 3-O-rhamnoside-7-O-glucoside
REFERENCE   PMID:3994393
  AUTHORS   De Luca V, Ibrahim RK
  TITLE     Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. I. Partial purification and some properties of S-adenosyl-L-methionine:flavonol 3-, 6-, 7-, and 4'-O-methyltransferases.
  JOURNAL   Arch Biochem Biophys 238:596-605 (1985)
            DOI:10.1016/0003-9861(85)90205-X
REFERENCE   PMID:6462109
  AUTHORS   Jourdan PS, Mansell RL
  TITLE     Isolation and partial characterization of three glucosyl transferases involved in the biosynthesis of flavonol triglucosides in Pisum sativum L.
  JOURNAL   Arch Biochem Biophys 213:434-43 (1982)
            DOI:10.1016/0003-9861(82)90569-0
REFERENCE   PMID:10567367
  AUTHORS   Miller KD, Guyon V, Evans JN, Shuttleworth WA, Taylor LP
  TITLE     Purification, cloning, and heterologous expression of a catalytically efficient flavonol 3-O-galactosyltransferase expressed in the male gametophyte of Petunia hybrida.
  JOURNAL   J Biol Chem 274:34011-9 (1999)
            DOI:10.1074/jbc.274.48.34011
REFERENCE   PMID:12482447
  AUTHORS   Cacace S, Schroder G, Wehinger E, Strack D, Schmidt J, Schroder J
  TITLE     A flavonol O-methyltransferase from Catharanthus roseus performing two sequential methylations.
  JOURNAL   Phytochemistry 62:127-37 (2003)
            DOI:10.1016/S0031-9422(02)00483-1
REFERENCE   PMID:15807784
  AUTHORS   Tohge T, Nishiyama Y, Hirai MY, Yano M, Nakajima J, Awazuhara M, Inoue E, Takahashi H, Goodenowe DB, Kitayama M, Noji M, Yamazaki M, Saito K
  TITLE     Functional genomics by integrated analysis of metabolome and transcriptome of Arabidopsis plants over-expressing an MYB transcription factor.
  JOURNAL   Plant J 42:218-35 (2005)
            DOI:10.1111/j.1365-313X.2005.02371.x
REFERENCE   PMID:17277900
  AUTHORS   Kubo H, Nawa N, Lupsea SA
  TITLE     Anthocyaninless1 gene of Arabidopsis thaliana encodes a UDP-glucose:flavonoid-3-O-glucosyltransferase.
  JOURNAL   J Plant Res 120:445-9 (2007)
            DOI:10.1007/s10265-006-0067-7
REFERENCE   PMID:24241851
  AUTHORS   Knogge W, Weissenbock G
  TITLE     Tissue-distribution of secondary phenolic biosynthesis in developing primary leaves of Avena sativa L.
  JOURNAL   Planta 167:196-205 (1986)
            DOI:10.1007/BF00391415
REFERENCE   PMID:24177970
  AUTHORS   Anhalt S, Weissenbock G
  TITLE     Subcellular localization of luteolin glucuronides and related enzymes in rye mesophyll.
  JOURNAL   Planta 187:83-8 (1992)
            DOI:10.1007/BF00201627
REFERENCE   
  AUTHORS   Suzuki H, Nakayama T, Nagae S, Yamaguchi M, Iwashita T, Fukui Y, Nishino T.
  TITLE     cDNA cloning and functional characterization of flavonol 3-O-glucoside-6"-O-malonyltransferases from flowers of Verbena hybrida and Lamium purpureum.
  JOURNAL   J Mol Catal B 28:87-93 (2004)
            DOI:10.1016/j.molcatb.2004.01.005
REL_PATHWAY osa00941  Flavonoid biosynthesis
KO_PATHWAY  ko00944
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