ENTRY       mtr00940                    Pathway
NAME        Phenylpropanoid biosynthesis - Medicago truncatula (barrel medic)
DESCRIPTION Phenylpropanoids are a group of plant secondary metabolites derived from phenylalanine and having a wide variety of functions both as structural and signaling molecules. Phenylalanine is first converted to cinnamic acid by deamination. It is followed by hydroxylation and frequent methylation to generate coumaric acid and other acids with a phenylpropane (C6-C3) unit. Reduction of the CoA-activated carboxyl groups of these acids results in the corresponding aldehydes and alcohols. The alcohols are called monolignols, the starting compounds for biosynthesis of lignin.
CLASS       Metabolism; Biosynthesis of other secondary metabolites
PATHWAY_MAP mtr00940  Phenylpropanoid biosynthesis
MODULE      mtr_M00039  Monolignol biosynthesis, phenylalanine/tyrosine => monolignol [PATH:mtr00940]
            mtr_M00137  Flavanone biosynthesis, phenylalanine => naringenin [PATH:mtr00940]
DBLINKS     GO: 0009699
ORGANISM    Medicago truncatula (barrel medic) [GN:mtr]
GENE        25499317  phenylalanine ammonia-lyase [KO:K10775] [EC:4.3.1.24]
            120576914  phenylalanine ammonia-lyase [KO:K10775] [EC:4.3.1.24]
            25499316  phenylalanine ammonia-lyase [KO:K10775] [EC:4.3.1.24]
            11429351  phenylalanine ammonia-lyase class 3 [KO:K10775] [EC:4.3.1.24]
            25487825  phenylalanine ammonia-lyase [KO:K10775] [EC:4.3.1.24]
            11434138  phenylalanine ammonia-lyase [KO:K10775] [EC:4.3.1.24]
            11414166  phenylalanine ammonia-lyase 2 [KO:K10775] [EC:4.3.1.24]
            11442075  trans-cinnamate 4-monooxygenase [KO:K00487] [EC:1.14.14.91]
            25485521  cytochrome P450 CYP73A100 [KO:K00487] [EC:1.14.14.91]
            11441228  4-coumarate--CoA ligase-like 6 [KO:K01904] [EC:6.2.1.12]
            11419136  4-coumarate--CoA ligase-like 9 [KO:K01904] [EC:6.2.1.12]
            11414035  4-coumarate--CoA ligase-like 9 [KO:K01904] [EC:6.2.1.12]
            11429318  4-coumarate--CoA ligase 1 [KO:K01904] [EC:6.2.1.12]
            25492399  4-coumarate--CoA ligase-like 7 [KO:K01904] [EC:6.2.1.12]
            11426040  4-coumarate--CoA ligase 2 [KO:K01904] [EC:6.2.1.12]
            11406508  4-coumarate--CoA ligase-like 6 [KO:K01904] [EC:6.2.1.12]
            11410073  4-coumarate--CoA ligase-like 6 [KO:K01904] [EC:6.2.1.12]
            25494254  4-coumarate--CoA ligase isoform X2 [KO:K01904] [EC:6.2.1.12]
            25490723  4-coumarate--CoA ligase-like 1 [KO:K01904] [EC:6.2.1.12]
            25487863  4-coumarate--CoA ligase-like 7 [KO:K01904] [EC:6.2.1.12]
            25488009  LOW QUALITY PROTEIN: 4-coumarate--CoA ligase 1 [KO:K01904] [EC:6.2.1.12]
            11438044  shikimate O-hydroxycinnamoyltransferase [KO:K13065] [EC:2.3.1.133]
            11446414  stemmadenine O-acetyltransferase [KO:K13065] [EC:2.3.1.133]
            11446012  spermidine hydroxycinnamoyl transferase [KO:K13065] [EC:2.3.1.133]
            11443511  LOW QUALITY PROTEIN: spermidine hydroxycinnamoyl transferase [KO:K13065] [EC:2.3.1.133]
            11428237  spermidine hydroxycinnamoyl transferase [KO:K13065] [EC:2.3.1.133]
            25491195  shikimate O-hydroxycinnamoyltransferase [KO:K13065] [EC:2.3.1.133]
            11413387  spermidine hydroxycinnamoyl transferase [KO:K13065] [EC:2.3.1.133]
            11431043  spermidine hydroxycinnamoyl transferase [KO:K13065] [EC:2.3.1.133]
            25486922  shikimate O-hydroxycinnamoyltransferase [KO:K13065] [EC:2.3.1.133]
            25487997  shikimate O-hydroxycinnamoyltransferase [KO:K13065] [EC:2.3.1.133]
            11441023  hydroxycinnamoyltransferase [KO:K13065] [EC:2.3.1.133]
            11415221  stemmadenine O-acetyltransferase [KO:K13065] [EC:2.3.1.133]
            11439545  shikimate O-hydroxycinnamoyltransferase [KO:K13065] [EC:2.3.1.133]
            11441050  spermidine hydroxycinnamoyl transferase [KO:K13065] [EC:2.3.1.133]
            11437276  spermidine hydroxycinnamoyl transferase [KO:K13065] [EC:2.3.1.133]
            120576930  cytochrome P450 98A2 [KO:K09754] [EC:1.14.14.96]
            25485736  caffeoylshikimate esterase isoform X2 [KO:K18368] [EC:3.1.1.-]
            25497428  caffeoylshikimate esterase isoform X4 [KO:K18368] [EC:3.1.1.-]
            11445793  caffeoylshikimate esterase [KO:K18368] [EC:3.1.1.-]
            11405169  caffeoylshikimate esterase [KO:K18368] [EC:3.1.1.-]
            11422536  caffeoylshikimate esterase [KO:K18368] [EC:3.1.1.-]
            11417168  caffeoylshikimate esterase isoform X1 [KO:K18368] [EC:3.1.1.-]
            11420987  caffeoylshikimate esterase [KO:K18368] [EC:3.1.1.-]
            11407567  probable caffeoyl-CoA O-methyltransferase At4g26220 [KO:K00588] [EC:2.1.1.104]
            25500555  probable caffeoyl-CoA O-methyltransferase At4g26220 [KO:K00588] [EC:2.1.1.104]
            11446939  caffeoyl-CoA O-methyltransferase [KO:K00588] [EC:2.1.1.104]
            25493320  flavonoid 3',5'-methyltransferase [KO:K00588] [EC:2.1.1.104]
            25493460  caffeoyl-CoA O-methyltransferase 5 [KO:K00588] [EC:2.1.1.104]
            25493461  caffeoyl-CoA O-methyltransferase 2 [KO:K00588] [EC:2.1.1.104]
            25493481  caffeoyl-CoA O-methyltransferase [KO:K00588] [EC:2.1.1.104]
            25493490  caffeoyl-CoA O-methyltransferase [KO:K00588] [EC:2.1.1.104]
            11439410  probable caffeoyl-CoA O-methyltransferase At4g26220 [KO:K00588] [EC:2.1.1.104]
            11424763  cinnamoyl-CoA reductase 1 [KO:K09753] [EC:1.2.1.44]
            25487973  cinnamoyl-CoA reductase 1 [KO:K09753] [EC:1.2.1.44]
            11422599  aldehyde dehydrogenase family 2 member C4 [KO:K12355] [EC:1.2.1.68]
            11409735  aldehyde dehydrogenase family 2 member C4-like [KO:K12355] [EC:1.2.1.68]
            11442573  aldehyde dehydrogenase family 2 member C4 [KO:K12355] [EC:1.2.1.68]
            11439969  aldehyde dehydrogenase family 2 member C4 [KO:K12355] [EC:1.2.1.68]
            11411326  cytochrome P450 84A1 [KO:K09755] [EC:1.14.-.-]
            11440199  cytochrome P450 84A1 [KO:K09755] [EC:1.14.-.-]
            11414355  cytochrome P450 84A1 [KO:K09755] [EC:1.14.-.-]
            11428747  caffeic acid 3-O-methyltransferase [KO:K13066] [EC:2.1.1.68 2.1.1.4]
            25481245  caffeic acid 3-O-methyltransferase [KO:K13066] [EC:2.1.1.68 2.1.1.4]
            11421675  caffeic acid 3-O-methyltransferase [KO:K13066] [EC:2.1.1.68 2.1.1.4]
            25501428  caffeic acid 3-O-methyltransferase [KO:K13066] [EC:2.1.1.68 2.1.1.4]
            11417290  caffeic acid 3-O-methyltransferase [KO:K13066] [EC:2.1.1.68 2.1.1.4]
            25501432  caffeic acid 3-O-methyltransferase [KO:K13066] [EC:2.1.1.68 2.1.1.4]
            25501425  LOW QUALITY PROTEIN: anthranilate N-methyltransferase [KO:K13066] [EC:2.1.1.68 2.1.1.4]
            25501426  caffeic acid 3-O-methyltransferase isoform X1 [KO:K13066] [EC:2.1.1.68 2.1.1.4]
            25501422  LOW QUALITY PROTEIN: caffeic acid 3-O-methyltransferase [KO:K13066] [EC:2.1.1.68 2.1.1.4]
            11428411  caffeic acid 3-O-methyltransferase 1 isoform X2 [KO:K13066] [EC:2.1.1.68 2.1.1.4]
            11421609  probable cinnamyl alcohol dehydrogenase 1 isoform X2 [KO:K00083] [EC:1.1.1.195]
            11420425  probable cinnamyl alcohol dehydrogenase 6 [KO:K00083] [EC:1.1.1.195]
            25485411  probable cinnamyl alcohol dehydrogenase [KO:K00083] [EC:1.1.1.195]
            11416804  berberine bridge enzyme-like 13 [KO:K22395] [EC:1.1.1.195]
            25493365  berberine bridge enzyme-like 13 [KO:K22395] [EC:1.1.1.195]
            25493366  berberine bridge enzyme-like 13 [KO:K22395] [EC:1.1.1.195]
            25493431  1-Cys peroxiredoxin [KO:K11188] [EC:1.11.1.7 1.11.1.27 3.1.1.-]
            11424906  peroxidase 43 isoform X1 [KO:K00430] [EC:1.11.1.7]
            11421602  cationic peroxidase 2 [KO:K00430] [EC:1.11.1.7]
            25497808  peroxidase 55 [KO:K00430] [EC:1.11.1.7]
            11426600  peroxidase E5 [KO:K00430] [EC:1.11.1.7]
            11413831  peroxidase A2 [KO:K00430] [EC:1.11.1.7]
            11415919  peroxidase E5 [KO:K00430] [EC:1.11.1.7]
            11412423  peroxidase E5 [KO:K00430] [EC:1.11.1.7]
            11407620  peroxidase E5 [KO:K00430] [EC:1.11.1.7]
            11410170  peroxidase 15 [KO:K00430] [EC:1.11.1.7]
            11412424  peroxidase 15 [KO:K00430] [EC:1.11.1.7]
            11413832  peroxidase 15 [KO:K00430] [EC:1.11.1.7]
            11426602  peroxidase 15 [KO:K00430] [EC:1.11.1.7]
            11413855  peroxidase A2 [KO:K00430] [EC:1.11.1.7]
            11437724  peroxidase N [KO:K00430] [EC:1.11.1.7]
            11409509  peroxidase P7 [KO:K00430] [EC:1.11.1.7]
            11411032  peroxidase P7 [KO:K00430] [EC:1.11.1.7]
            11407145  peroxidase P7 [KO:K00430] [EC:1.11.1.7]
            11415635  peroxidase P7 [KO:K00430] [EC:1.11.1.7]
            11416629  peroxidase P7 [KO:K00430] [EC:1.11.1.7]
            11411022  peroxidase 31 [KO:K00430] [EC:1.11.1.7]
            11445351  peroxidase 64 [KO:K00430] [EC:1.11.1.7]
            11422576  peroxidase 72 [KO:K00430] [EC:1.11.1.7]
            25480458  LOW QUALITY PROTEIN: putative Peroxidase 48 [KO:K00430] [EC:1.11.1.7]
            11416048  peroxidase 3 [KO:K00430] [EC:1.11.1.7]
            25480499  peroxidase 47 [KO:K00430] [EC:1.11.1.7]
            25487290  putative Peroxidase 48 [KO:K00430] [EC:1.11.1.7]
            11408205  peroxidase P7 [KO:K00430] [EC:1.11.1.7]
            11415900  peroxidase P7 [KO:K00430] [EC:1.11.1.7]
            11413840  peroxidase 5 [KO:K00430] [EC:1.11.1.7]
            11444232  peroxidase 5 [KO:K00430] [EC:1.11.1.7]
            11440461  peroxidase P7 [KO:K00430] [EC:1.11.1.7]
            11418508  peroxidase P7 [KO:K00430] [EC:1.11.1.7]
            11440462  peroxidase P7 [KO:K00430] [EC:1.11.1.7]
            11439420  peroxidase 44 [KO:K00430] [EC:1.11.1.7]
            11431785  peroxidase 17 [KO:K00430] [EC:1.11.1.7]
            11425716  peroxidase 17 [KO:K00430] [EC:1.11.1.7]
            25495241  peroxidase 31 [KO:K00430] [EC:1.11.1.7]
            25495810  peroxidase 57 [KO:K00430] [EC:1.11.1.7]
            120578239  putative Peroxidase 48 [KO:K00430] [EC:1.11.1.7]
            11417426  peroxidase 22 [KO:K00430] [EC:1.11.1.7]
            25486974  putative Peroxidase 48 [KO:K00430] [EC:1.11.1.7]
            25492840  lignin-forming anionic peroxidase-like [KO:K00430] [EC:1.11.1.7]
            11441606  lignin-forming anionic peroxidase-like [KO:K00430] [EC:1.11.1.7]
            11444576  lignin-forming anionic peroxidase [KO:K00430] [EC:1.11.1.7]
            25496290  peroxidase 12 [KO:K00430] [EC:1.11.1.7]
            25496293  peroxidase 12 [KO:K00430] [EC:1.11.1.7]
            25496303  peroxidase 12 [KO:K00430] [EC:1.11.1.7]
            25494710  peroxidase 11 isoform X1 [KO:K00430] [EC:1.11.1.7]
            11405719  peroxidase 73 [KO:K00430] [EC:1.11.1.7]
            11441645  peroxidase 25 [KO:K00430] [EC:1.11.1.7]
            11417754  peroxidase 40 [KO:K00430] [EC:1.11.1.7]
            25491722  peroxidase P7 [KO:K00430] [EC:1.11.1.7]
            25491723  peroxidase P7 [KO:K00430] [EC:1.11.1.7]
            25491724  cationic peroxidase 1 [KO:K00430] [EC:1.11.1.7]
            25491725  cationic peroxidase 1 [KO:K00430] [EC:1.11.1.7]
            25492105  peroxidase 3 [KO:K00430] [EC:1.11.1.7]
            11441173  lignin-forming anionic peroxidase-like [KO:K00430] [EC:1.11.1.7]
            25493045  peroxidase 19 isoform X1 [KO:K00430] [EC:1.11.1.7]
            11444192  peroxidase 16 [KO:K00430] [EC:1.11.1.7]
            11435789  peroxidase 42 [KO:K00430] [EC:1.11.1.7]
            11438636  peroxidase 29 [KO:K00430] [EC:1.11.1.7]
            11439576  peroxidase 7 [KO:K00430] [EC:1.11.1.7]
            11431706  peroxidase 20 [KO:K00430] [EC:1.11.1.7]
            11424137  peroxidase 51 [KO:K00430] [EC:1.11.1.7]
            11411940  peroxidase 10 [KO:K00430] [EC:1.11.1.7]
            11405486  peroxidase 10 [KO:K00430] [EC:1.11.1.7]
            11412353  peroxidase 72 [KO:K00430] [EC:1.11.1.7]
            11428474  peroxidase 64 [KO:K00430] [EC:1.11.1.7]
            11407880  peroxidase 28 [KO:K00430] [EC:1.11.1.7]
            25494212  peroxidase N [KO:K00430] [EC:1.11.1.7]
            25491016  cationic peroxidase 1 [KO:K00430] [EC:1.11.1.7]
            25491018  peroxidase 4 [KO:K00430] [EC:1.11.1.7]
            25491105  peroxidase P7 [KO:K00430] [EC:1.11.1.7]
            11406538  cationic peroxidase 1 [KO:K00430] [EC:1.11.1.7]
            11412365  cationic peroxidase 1 [KO:K00430] [EC:1.11.1.7]
            11411139  cationic peroxidase 1 [KO:K00430] [EC:1.11.1.7]
            11426647  peroxidase P7 [KO:K00430] [EC:1.11.1.7]
            11433612  peroxidase 4 [KO:K00430] [EC:1.11.1.7]
            11429686  peroxidase P7 [KO:K00430] [EC:1.11.1.7]
            25486301  peroxidase A2 [KO:K00430] [EC:1.11.1.7]
            25486302  peroxidase 15 [KO:K00430] [EC:1.11.1.7]
            25488202  peroxidase 7 [KO:K00430] [EC:1.11.1.7]
            25486973  putative Peroxidase 48 [KO:K00430] [EC:1.11.1.7]
            25487245  putative Peroxidase 48 [KO:K00430] [EC:1.11.1.7]
            25487268  putative Peroxidase 48 [KO:K00430] [EC:1.11.1.7]
            25487295  putative Peroxidase 48 [KO:K00430] [EC:1.11.1.7]
            25487428  peroxidase P7 [KO:K00430] [EC:1.11.1.7]
            25487914  probable peroxidase 26 [KO:K00430] [EC:1.11.1.7]
            25481868  peroxidase 45 [KO:K00430] [EC:1.11.1.7]
            11414547  peroxidase 9 [KO:K00430] [EC:1.11.1.7]
            11415324  peroxidase 64 isoform X1 [KO:K00430] [EC:1.11.1.7]
            11418861  peroxidase 5 [KO:K00430] [EC:1.11.1.7]
            11430516  peroxidase 21 [KO:K00430] [EC:1.11.1.7]
            11445887  cationic peroxidase 1 [KO:K00430] [EC:1.11.1.7]
            11442078  cationic peroxidase 1 [KO:K00430] [EC:1.11.1.7]
            11427248  cationic peroxidase 1 [KO:K00430] [EC:1.11.1.7]
            25483534  peroxidase A2 [KO:K00430] [EC:1.11.1.7]
            25484028  peroxidase 21 isoform X3 [KO:K00430] [EC:1.11.1.7]
            25484030  peroxidase 21 [KO:K00430] [EC:1.11.1.7]
            11413841  peroxidase 5 [KO:K00430] [EC:1.11.1.7]
            11413151  peroxidase 66 [KO:K00430] [EC:1.11.1.7]
            11428337  cationic peroxidase 1 [KO:K00430] [EC:1.11.1.7]
            11430155  peroxidase 44 [KO:K00430] [EC:1.11.1.7]
            11419467  peroxidase A2 [KO:K00430] [EC:1.11.1.7]
            25484508  peroxidase 47 [KO:K00430] [EC:1.11.1.7]
            25484835  peroxidase 41 [KO:K00430] [EC:1.11.1.7]
            11444315  anthocyanidin 3-O-glucosyltransferase 5 [KO:K12356] [EC:2.4.1.111]
            11409947  UDP-glycosyltransferase 72E1 [KO:K12356] [EC:2.4.1.111]
COMPOUND    C00079  L-Phenylalanine
            C00082  L-Tyrosine
            C00223  p-Coumaroyl-CoA
            C00315  Spermidine
            C00323  Caffeoyl-CoA
            C00406  Feruloyl-CoA
            C00411  Sinapoyl-CoA
            C00423  trans-Cinnamate
            C00482  Sinapate
            C00540  Cinnamoyl-CoA
            C00590  Coniferyl alcohol
            C00761  Coniferin
            C00811  4-Coumarate
            C00852  Chlorogenate
            C00903  Cinnamaldehyde
            C00933  Sinapine
            C01175  1-O-Sinapoyl-beta-D-glucose
            C01197  Caffeate
            C01494  Ferulate
            C01533  Syringin
            C02325  Sinapyl alcohol
            C02646  4-Coumaryl alcohol
            C02666  Coniferyl aldehyde
            C02887  Sinapoyl malate
            C02947  4-Coumaroylshikimate
            C04366  3-(2-Carboxyethenyl)-cis,cis-muconate
            C05608  4-Hydroxycinnamyl aldehyde
            C05610  Sinapoyl aldehyde
            C05619  5-Hydroxyferulic acid
            C05627  4-Hydroxystyrene
            C05855  4-Hydroxycinnamyl alcohol 4-D-glucoside
            C06224  3,4-Dihydroxystyrene
            C10428  Anethole
            C10434  5-O-Caffeoylshikimic acid
            C10452  Estragole
            C10453  Eugenol
            C10454  Methyleugenol
            C10469  Isoeugenol
            C10478  Methylisoeugenol
            C10945  Caffeic aldehyde
            C12203  5-Hydroxyferuloyl-CoA
            C12204  5-Hydroxyconiferaldehyde
            C12205  5-Hydroxyconiferyl alcohol
            C12206  Caffeyl alcohol
            C12208  p-Coumaroyl quinic acid
            C15804  p-Hydroxyphenyl lignin
            C15805  Guaiacyl lignin
            C15806  Syringyl lignin
            C15807  5-Hydroxy-guaiacyl lignin
            C16930  Chavicol
            C18069  N1,N5,N10-Tricoumaroyl spermidine
            C18070  N1,N5,N10-Tricaffeoyl spermidine
            C18071  N1,N5,N10-Triferuloyl spermidine
            C18072  N1,N5,N10-Tri(hydroxyferuloyl) spermidine
            C18073  N1,N5-Di(hydroxyferuloyl)-N10-sinapoyl spermidine
            C20225  Coniferyl acetate
            C20464  Isochavicol
            C20465  Coumaryl acetate
REFERENCE   PMID:14729911
  AUTHORS   Nair RB, Bastress KL, Ruegger MO, Denault JW, Chapple C.
  TITLE     The Arabidopsis thaliana REDUCED EPIDERMAL FLUORESCENCE1 gene encodes an aldehyde dehydrogenase involved in ferulic acid and sinapic acid biosynthesis.
  JOURNAL   Plant Cell 16:544-54 (2004)
            DOI:10.1105/tpc.017509
REFERENCE   PMID:14551235
  AUTHORS   Baucher M, Halpin C, Petit-Conil M, Boerjan W.
  TITLE     Lignin: genetic engineering and impact on pulping.
  JOURNAL   Crit Rev Biochem Mol Biol 38:305-50 (2003)
            DOI:10.1080/10409230391036757
REFERENCE   PMID:15878986
  AUTHORS   Rogers LA, Dubos C, Cullis IF, Surman C, Poole M, Willment J, Mansfield SD, Campbell MM.
  TITLE     Light, the circadian clock, and sugar perception in the control of lignin biosynthesis.
  JOURNAL   J Exp Bot 56:1651-63 (2005)
            DOI:10.1093/jxb/eri162
REFERENCE   PMID:12242395
  AUTHORS   Whetten R, Sederoff R.
  TITLE     Lignin Biosynthesis.
  JOURNAL   Plant Cell 7:1001-1013 (1995)
            DOI:10.1105/tpc.7.7.1001
REFERENCE   PMID:8972602
  AUTHORS   Lorenzen M, Racicot V, Strack D, Chapple C.
  TITLE     Sinapic acid ester metabolism in wild type and a sinapoylglucose-accumulating mutant of arabidopsis.
  JOURNAL   Plant Physiol 112:1625-30 (1996)
            DOI:10.1104/pp.112.4.1625
REFERENCE   PMID:1477555
  AUTHORS   Chapple CC, Vogt T, Ellis BE, Somerville CR.
  TITLE     An Arabidopsis mutant defective in the general phenylpropanoid pathway.
  JOURNAL   Plant Cell 4:1413-24 (1992)
            DOI:10.1105/tpc.4.11.1413
REFERENCE   PMID:14612585
  AUTHORS   Raes J, Rohde A, Christensen JH, Van de Peer Y, Boerjan W.
  TITLE     Genome-wide characterization of the lignification toolbox in Arabidopsis.
  JOURNAL   Plant Physiol 133:1051-71 (2003)
            DOI:10.1104/pp.103.026484
REFERENCE   PMID:14568076
  AUTHORS   Costa MA, Collins RE, Anterola AM, Cochrane FC, Davin LB, Lewis NG.
  TITLE     An in silico assessment of gene function and organization of the phenylpropanoid pathway metabolic networks in Arabidopsis thaliana and limitations thereof.
  JOURNAL   Phytochemistry 64:1097-112 (2003)
            DOI:10.1016/S0031-9422(03)00517-X
REFERENCE   PMID:10934215
  AUTHORS   Meyermans H, Morreel K, Lapierre C, Pollet B, De Bruyn A, Busson R, Herdewijn P, Devreese B, Van Beeumen J, Marita JM, Ralph J, Chen C, Burggraeve B, Van Montagu M, Messens E, Boerjan W.
  TITLE     Modifications in lignin and accumulation of phenolic glucosides in poplar xylem upon down-regulation of caffeoyl-coenzyme A O-methyltransferase, an enzyme involved in lignin biosynthesis.
  JOURNAL   J Biol Chem 275:36899-909 (2000)
            DOI:10.1074/jbc.M006915200
REFERENCE   PMID:16027976
  AUTHORS   Gachon CM, Langlois-Meurinne M, Henry Y, Saindrenan P.
  TITLE     Transcriptional co-regulation of secondary metabolism enzymes in Arabidopsis: functional and evolutionary implications.
  JOURNAL   Plant Mol Biol 58:229-45 (2005)
            DOI:10.1007/s11103-005-5346-5
REFERENCE   PMID:10692459
  AUTHORS   Li L, Popko JL, Umezawa T, Chiang VL.
  TITLE     5-hydroxyconiferyl aldehyde modulates enzymatic methylation for syringyl monolignol formation, a new view of monolignol biosynthesis in angiosperms.
  JOURNAL   J Biol Chem 275:6537-45 (2000)
            DOI:10.1074/jbc.275.9.6537
REFERENCE   PMID:12009990
  AUTHORS   Yamauchi K, Yasuda S, Fukushima K.
  TITLE     Evidence for the biosynthetic pathway from sinapic acid to syringyl lignin using labeled sinapic acid with stable isotope at both methoxy groups in Robinia pseudoacacia and Nerium indicum.
  JOURNAL   J Agric Food Chem 50:3222-7 (2002)
            DOI:10.1021/jf011565x
REFERENCE   PMID:12084820
  AUTHORS   Eckardt NA.
  TITLE     Probing the mysteries of lignin biosynthesis: the crystal structure of caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase provides new insights.
  JOURNAL   Plant Cell 14:1185-9 (2002)
            DOI:10.1105/tpc.140610
REL_PATHWAY mtr00130  Ubiquinone and other terpenoid-quinone biosynthesis
            mtr00400  Phenylalanine, tyrosine and tryptophan biosynthesis
            mtr00941  Flavonoid biosynthesis
            mtr00945  Stilbenoid, diarylheptanoid and gingerol biosynthesis
KO_PATHWAY  ko00940
///
