ENTRY       mtr00100                    Pathway
NAME        Steroid biosynthesis - Medicago truncatula (barrel medic)
CLASS       Metabolism; Lipid metabolism
PATHWAY_MAP mtr00100  Steroid biosynthesis
MODULE      mtr_M00917  Phytosterol biosynthesis, squalene 2,3-epoxide => campesterol/sitosterol [PATH:mtr00100]
DBLINKS     GO: 0016126
ORGANISM    Medicago truncatula (barrel medic) [GN:mtr]
GENE        11441556  squalene synthase 2 [KO:K00801] [EC:2.5.1.21]
            11415396  squalene monooxygenase SE1 isoform X1 [KO:K00511] [EC:1.14.14.17]
            25496080  squalene monooxygenase SE1 isoform X1 [KO:K00511] [EC:1.14.14.17]
            25496089  squalene monooxygenase SE1 [KO:K00511] [EC:1.14.14.17]
            25490000  squalene monooxygenase SE1 [KO:K00511] [EC:1.14.14.17]
            25482032  squalene monooxygenase SE1 [KO:K00511] [EC:1.14.14.17]
            11432420  obtusifoliol 14-alpha demethylase [KO:K05917] [EC:1.14.14.154 1.14.15.36]
            25500003  sterol 14-demethylase [KO:K05917] [EC:1.14.14.154 1.14.15.36]
            25483897  delta(14)-sterol reductase [KO:K00222] [EC:1.3.1.70]
            25496873  probable 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase [KO:K01824] [EC:5.3.3.5]
            25492834  delta(24)-sterol reductase [KO:K09828] [EC:1.3.1.72 1.3.1.-]
            25495643  delta(7)-sterol-C5(6)-desaturase isoform X1 [KO:K00227] [EC:1.14.19.20]
            25491175  7-dehydrocholesterol reductase [KO:K00213] [EC:1.3.1.21]
            25493363  7-dehydrocholesterol reductase isoform X1 [KO:K00213] [EC:1.3.1.21]
            25489611  triacylglycerol lipase 2 [KO:K01052] [EC:3.1.1.13]
            112416075  triacylglycerol lipase 2 [KO:K01052] [EC:3.1.1.13]
            25495998  triacylglycerol lipase 2 [KO:K01052] [EC:3.1.1.13]
            25495999  triacylglycerol lipase 2-like [KO:K01052] [EC:3.1.1.13]
            25497846  triacylglycerol lipase 2 isoform X1 [KO:K01052] [EC:3.1.1.13]
            11440941  triacylglycerol lipase 2 [KO:K01052] [EC:3.1.1.13]
            25489613  triacylglycerol lipase 2 [KO:K01052] [EC:3.1.1.13]
            11438382  triacylglycerol lipase 2 [KO:K01052] [EC:3.1.1.13]
            25485394  triacylglycerol lipase 1 [KO:K01052] [EC:3.1.1.13]
            11412275  triacylglycerol lipase SDP1 isoform X1 [KO:K14674] [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
            25496763  triacylglycerol lipase SDP1 [KO:K14674] [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
            11414821  triacylglycerol lipase SDP1 [KO:K14674] [EC:3.1.1.3 3.1.1.13 3.1.1.4 2.3.1.51]
            11415411  cycloartenol-C-24-methyltransferase isoform X1 [KO:K00559] [EC:2.1.1.41]
            25497029  cycloartenol synthase-like isoform X2 [KO:K01853] [EC:5.4.99.8]
            11427580  LOW QUALITY PROTEIN: cycloartenol synthase-like [KO:K01853] [EC:5.4.99.8]
            25498491  cycloartenol synthase isoform X1 [KO:K01853] [EC:5.4.99.8]
            11428926  cycloartenol synthase isoform X1 [KO:K01853] [EC:5.4.99.8]
            25498869  methylsterol monooxygenase 1-1 [KO:K14423] [EC:1.14.18.10]
            11426366  methylsterol monooxygenase 1-1 [KO:K14423] [EC:1.14.18.10]
            11412484  3beta-hydroxysteroid-dehydrogenase/decarboxylase isoform X1 [KO:K23558] [EC:1.1.1.418]
            11426731  3beta-hydroxysteroid- dehydrogenase/decarboxylase [KO:K23558] [EC:1.1.1.418]
            11427814  cycloeucalenol cycloisomerase isoform X2 [KO:K08246] [EC:5.5.1.9]
            11436684  24-methylenesterol C-methyltransferase 2 [KO:K08242] [EC:2.1.1.143]
            11410003  methylsterol monooxygenase 2-2 [KO:K14424] [EC:1.14.18.11]
            120575921  methylsterol monooxygenase 2-1-like isoform X1 [KO:K14424] [EC:1.14.18.11]
            25496266  methylsterol monooxygenase 2-2 isoform X2 [KO:K14424] [EC:1.14.18.11]
            11407532  methylsterol monooxygenase 2-2 [KO:K14424] [EC:1.14.18.11]
            11437817  cytochrome P450 710A1 [KO:K09832] [EC:1.14.19.41]
COMPOUND    C00187  Cholesterol
            C00448  trans,trans-Farnesyl diphosphate
            C00751  Squalene
            C01054  (S)-2,3-Epoxysqualene
            C01164  7-Dehydrocholesterol
            C01189  Lathosterol
            C01561  Calcidiol
            C01673  Calcitriol
            C01694  Ergosterol
            C01724  Lanosterol
            C01753  beta-Sitosterol
            C01789  Campesterol
            C01802  Desmosterol
            C01902  Cycloartenol
            C01943  Obtusifoliol
            C02141  Cycloeucalenol
            C02530  Cholesterol ester
            C03428  Presqualene diphosphate
            C03845  5alpha-Cholest-8-en-3beta-ol
            C04525  Fecosterol
            C05103  4alpha-Methylzymosterol
            C05107  7-Dehydrodesmosterol
            C05108  14-Demethyllanosterol
            C05109  24,25-Dihydrolanosterol
            C05437  Zymosterol
            C05439  5alpha-Cholesta-7,24-dien-3beta-ol
            C05440  Ergosta-5,7,22,24(28)-tetraen-3beta-ol
            C05441  Vitamin D2
            C05442  Stigmasterol
            C05443  Vitamin D3
            C07712  Secalciferol
            C08813  Brassicasterol
            C08821  Isofucosterol
            C08830  24-Methylidenecycloartanol
            C11455  4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol
            C11508  4alpha-Methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol
            C11522  24-Methylenelophenol
            C11523  24-Ethylidenelophenol
            C15776  4alpha-Methylfecosterol
            C15777  Episterol
            C15780  5-Dehydroepisterol
            C15781  24-Methylenecholesterol
            C15782  Delta7-Avenasterol
            C15783  5-Dehydroavenasterol
            C15808  4alpha-Methylzymosterol-4-carboxylate
            C15816  3-Keto-4-methylzymosterol
            C15915  4,4-Dimethyl-5alpha-cholesta-8-en-3beta-ol
            C18231  Calcitetrol
            C21106  24-epi-Campesterol
            C22112  4alpha-Carboxy-5alpha-cholesta-8,24-dien-3beta-ol
            C22116  3beta-Hydroxy-4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(24(1))-en-4alpha-carboxylate
            C22119  3beta-Hydroxyergosta-7,24(24(1))-dien-4alpha-carboxylate
            C22120  4alpha-Carboxy-stigmasta-7,24(24(1))-dien-3beta-ol
            C22121  Cycloeucalenone
            C22122  Episterone
            C22123  Avenastenone
            C22136  Zymosterone
REFERENCE   
  AUTHORS   Koshiba K, Kamiya Y.
  TITLE     [Atarasii Syokubutuhorumon no Kagaku] (In Japanese)
  JOURNAL   Koudansya saientific:199-138 (2002)
REFERENCE   PMID:16531502
  AUTHORS   Morikawa T, Mizutani M, Aoki N, Watanabe B, Saga H, Saito S, Oikawa A, Suzuki H, Sakurai N, Shibata D, Wadano A, Sakata K, Ohta D.
  TITLE     Cytochrome P450 CYP710A encodes the sterol C-22 desaturase in Arabidopsis and tomato.
  JOURNAL   Plant Cell 18:1008-22 (2006)
            DOI:10.1105/tpc.105.036012
REFERENCE   PMID:12777052
  AUTHORS   Lange BM, Ghassemian M.
  TITLE     Genome organization in Arabidopsis thaliana: a survey for genes involved in isoprenoid and chlorophyll metabolism.
  JOURNAL   Plant Mol Biol 51:925-48 (2003)
            DOI:10.1023/A:1023005504702
REL_PATHWAY mtr00900  Terpenoid backbone biosynthesis
            mtr00905  Brassinosteroid biosynthesis
KO_PATHWAY  ko00100
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