ENTRY       gmx00270                    Pathway
NAME        Cysteine and methionine metabolism - Glycine max (soybean)
DESCRIPTION Cysteine and methionine are sulfur-containing amino acids. Cysteine is synthesized from serine through different pathways in different organism groups. In bacteria and plants, cysteine is converted from serine (via acetylserine) by transfer of hydrogen sulfide [MD:M00021]. In animals, methionine-derived homocysteine is used as sulfur source and its condensation product with serine (cystathionine) is converted to cysteine [MD:M00338]. Cysteine is metabolized to pyruvate in multiple routes. Methionine is an essential amino acid, which animals cannot synthesize. In bacteria and plants, methionine is synthesized from aspartate [MD:M00017]. S-Adenosylmethionine (SAM), synthesized from methionine and ATP, is a methyl group donor in many important transfer reactions including DNA methylation for regulation of gene expression. SAM may also be used to regenerate methionine in the methionine salvage pathway [MD:M00034].
CLASS       Metabolism; Amino acid metabolism
PATHWAY_MAP gmx00270  Cysteine and methionine metabolism
MODULE      gmx_M00021  Cysteine biosynthesis, serine => cysteine [PATH:gmx00270]
            gmx_M00034  Methionine salvage pathway [PATH:gmx00270]
            gmx_M00368  Ethylene biosynthesis, methionine => ethylene [PATH:gmx00270]
DBLINKS     GO: 0006534 0006555
ORGANISM    Glycine max (soybean) [GN:gmx]
GENE        547632  serine acetyltransferase [KO:K00640] [EC:2.3.1.30]
            100775449  serine acetyltransferase 2 isoform X2 [KO:K00640] [EC:2.3.1.30]
            100778586  serine acetyltransferase 2 [KO:K00640] [EC:2.3.1.30]
            100815091  serine acetyltransferase 5 [KO:K00640] [EC:2.3.1.30]
            100820316  serine acetyltransferase 1, chloroplastic [KO:K00640] [EC:2.3.1.30]
            100812677  serine acetyltransferase 2 isoform X3 [KO:K00640] [EC:2.3.1.30]
            100816378  serine acetyltransferase 3, mitochondrial [KO:K00640] [EC:2.3.1.30]
            100806181  serine acetyltransferase 1, chloroplastic [KO:K00640] [EC:2.3.1.30]
            100779106  serine acetyltransferase 1, chloroplastic [KO:K00640] [EC:2.3.1.30]
            100796461  serine acetyltransferase 2 isoform X2 [KO:K00640] [EC:2.3.1.30]
            606507  SAT1; serine acetyltransferase 1, chloroplastic [KO:K00640] [EC:2.3.1.30]
            547631  cysteine synthase [KO:K01738] [EC:2.5.1.47]
            100101865  OAS-TL1; cysteine synthase [KO:K01738] [EC:2.5.1.47]
            100815330  cysteine synthase [KO:K01738] [EC:2.5.1.47]
            100775420  uncharacterized protein LOC100775420 [KO:K01738] [EC:2.5.1.47]
            100101900  OAS-TL4; OAS-TL4 cysteine synthase [KO:K01738] [EC:2.5.1.47]
            100101866  OAS-TL2; cysteine synthase [KO:K01738] [EC:2.5.1.47]
            100101909  OAS-TL7; cysteine synthase [KO:K01738] [EC:2.5.1.47]
            100101867  OAS-TL6; cysteine synthase [KO:K01738] [EC:2.5.1.47]
            100818242  cysteine synthase isoform X1 [KO:K01738] [EC:2.5.1.47]
            100794958  cysteine synthase-like [KO:K01738] [EC:2.5.1.47]
            100799081  cysteine synthase 2 [KO:K01738] [EC:2.5.1.47]
            100804065  cysteine synthase isoform X2 [KO:K01738] [EC:2.5.1.47]
            100813180  LOW QUALITY PROTEIN: putative inactive cysteine synthase 2 [KO:K01738] [EC:2.5.1.47]
            100806420  beta-cyanoalanine synthase [KO:K13034] [EC:2.5.1.47 4.4.1.9]
            100101899  OAS-TL3; OAS-TL3 cysteine synthase [KO:K13034] [EC:2.5.1.47 4.4.1.9]
            100786470  cystathionine beta-lyase, chloroplastic-like [KO:K01760] [EC:4.4.1.13]
            100812354  cystathionine beta-lyase, chloroplastic [KO:K01760] [EC:4.4.1.13]
            100812265  homocysteine S-methyltransferase 1 isoform X1 [KO:K00547] [EC:2.1.1.10]
            100811127  homocysteine S-methyltransferase 3-like [KO:K00547] [EC:2.1.1.10]
            100790567  selenocysteine methyltransferase isoform X2 [KO:K00547] [EC:2.1.1.10]
            547643  methionine synthase [KO:K00549] [EC:2.1.1.14]
            100802039  putative cobalamin-independent methionine synthase [KO:K00549] [EC:2.1.1.14]
            100776541  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1 [KO:K00549] [EC:2.1.1.14]
            100811317  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase [KO:K00549] [EC:2.1.1.14]
            100779947  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1 [KO:K00549] [EC:2.1.1.14]
            100807833  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase [KO:K00549] [EC:2.1.1.14]
            100775388  5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase [KO:K00549] [EC:2.1.1.14]
            100777009  S-adenosylmethionine synthase-like [KO:K00789] [EC:2.5.1.6]
            100794248  S-adenosylmethionine synthase 3 [KO:K00789] [EC:2.5.1.6]
            100816602  S-adenosylmethionine synthase 1 [KO:K00789] [EC:2.5.1.6]
            100778809  S-adenosylmethionine synthase 1 [KO:K00789] [EC:2.5.1.6]
            100812341  S-adenosylmethionine synthase 1 [KO:K00789] [EC:2.5.1.6]
            100805448  S-adenosylmethionine synthase 3 [KO:K00789] [EC:2.5.1.6]
            100799139  S-adenosylmethionine synthase [KO:K00789] [EC:2.5.1.6]
            100777770  S-adenosylmethionine synthase 1 [KO:K00789] [EC:2.5.1.6]
            100787994  S-adenosylmethionine synthase [KO:K00789] [EC:2.5.1.6]
            100820392  S-adenosylmethionine synthase [KO:K00789] [EC:2.5.1.6]
            547981  SAMDC; S-adenosylmethionine decarboxylase [KO:K01611] [EC:4.1.1.50]
            100776059  S-adenosylmethionine decarboxylase proenzyme 4 [KO:K01611] [EC:4.1.1.50]
            100817029  S-adenosylmethionine decarboxylase proenzyme 4 [KO:K01611] [EC:4.1.1.50]
            100778203  S-adenosylmethionine decarboxylase proenzyme 4 [KO:K01611] [EC:4.1.1.50]
            100799463  uncharacterized protein LOC100799463 [KO:K01611] [EC:4.1.1.50]
            100800410  S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
            100784853  S-adenosylmethionine decarboxylase proenzyme 4 [KO:K01611] [EC:4.1.1.50]
            100790347  S-adenosylmethionine decarboxylase proenzyme [KO:K01611] [EC:4.1.1.50]
            100792107  uncharacterized protein LOC100792107 [KO:K00797] [EC:2.5.1.16]
            100792085  uncharacterized protein LOC100792085 [KO:K00797] [EC:2.5.1.16]
            100785862  spermidine synthase 2 [KO:K00797] [EC:2.5.1.16]
            100790506  uncharacterized protein LOC100790506 [KO:K00797] [EC:2.5.1.16]
            100812978  spermidine synthase isoform X1 [KO:K00797] [EC:2.5.1.16]
            100815244  spermine synthase [KO:K00797] [EC:2.5.1.16]
            100816988  spermine synthase [KO:K00797] [EC:2.5.1.16]
            100809346  spermidine synthase [KO:K00797] [EC:2.5.1.16]
            100788406  spermidine synthase 2 [KO:K00797] [EC:2.5.1.16]
            100802076  spermine synthase-like [KO:K00797] [EC:2.5.1.16]
            100776863  spermidine synthase 2 [KO:K00797] [EC:2.5.1.16]
            100775553  nicotianamine synthase [KO:K05953] [EC:2.5.1.43]
            100794250  nicotianamine synthase-like [KO:K05953] [EC:2.5.1.43]
            100803630  nicotianamine synthase [KO:K05953] [EC:2.5.1.43]
            100814069  nicotianamine synthase-like protein [KO:K05953] [EC:2.5.1.43]
            100819726  nicotianamine synthase [KO:K05953] [EC:2.5.1.43]
            100809191  5'-methylthioadenosine nucleosidase isoform X8 [KO:K01244] [EC:3.2.2.16]
            100779419  uncharacterized protein LOC100779419 [KO:K01244] [EC:3.2.2.16]
            100800253  5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase isoform X1 [KO:K01244] [EC:3.2.2.16]
            100818359  methylthioribose kinase [KO:K00899] [EC:2.7.1.100]
            100807564  methylthioribose kinase 1-like [KO:K00899] [EC:2.7.1.100]
            100799311  methylthioribose-1-phosphate isomerase-like [KO:K08963] [EC:5.3.1.23]
            100817732  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
            100794485  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
            100796209  probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1 [KO:K16054] [EC:4.2.1.109 3.1.3.77]
            100500592  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase-like protein [KO:K08967] [EC:1.13.11.53 1.13.11.54]
            100306042  putative 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase [KO:K08967] [EC:1.13.11.53 1.13.11.54]
            100812492  putative 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase [KO:K08967] [EC:1.13.11.53 1.13.11.54]
            100500632  1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase 4 [KO:K08967] [EC:1.13.11.53 1.13.11.54]
            100818968  probable N-succinyldiaminopimelate aminotransferase DapC [KO:K23977] [EC:2.6.1.117]
            100814682  probable N-succinyldiaminopimelate aminotransferase DapC [KO:K23977] [EC:2.6.1.117]
            732650  tyrosine aminotransferase [KO:K00815] [EC:2.6.1.5]
            100785132  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
            100800830  nicotianamine aminotransferase 1 [KO:K00815] [EC:2.6.1.5]
            100784392  probable aminotransferase TAT2 [KO:K00815] [EC:2.6.1.5]
            100776219  aromatic aminotransferase ISS1 [KO:K00837] [EC:2.6.1.-]
            100803887  aromatic aminotransferase ISS1-like [KO:K00837] [EC:2.6.1.-]
            100777207  methionine gamma-lyase [KO:K01761] [EC:4.4.1.11]
            100808736  methionine gamma-lyase [KO:K01761] [EC:4.4.1.11]
            100781016  methionine gamma-lyase [KO:K01761] [EC:4.4.1.11]
            100818307  DNA (cytosine-5)-methyltransferase CMT2 isoform X2 [KO:K00558] [EC:2.1.1.37]
            100802765  DNA (cytosine-5)-methyltransferase 1 [KO:K00558] [EC:2.1.1.37]
            100799480  DNA (cytosine-5)-methyltransferase CMT3 [KO:K00558] [EC:2.1.1.37]
            100797667  DNA (cytosine-5)-methyltransferase 1 [KO:K00558] [EC:2.1.1.37]
            100817688  putative DNA (cytosine-5)-methyltransferase CMT1 [KO:K00558] [EC:2.1.1.37]
            100798061  putative DNA (cytosine-5)-methyltransferase CMT1 [KO:K00558] [EC:2.1.1.37]
            100805944  uncharacterized protein LOC100805944 [KO:K17398] [EC:2.1.1.37]
            100792700  uncharacterized protein LOC100792700 [KO:K17398] [EC:2.1.1.37]
            100812480  uncharacterized protein LOC100812480 [KO:K17398] [EC:2.1.1.37]
            100786939  adenosylhomocysteinase [KO:K01251] [EC:3.13.2.1]
            100815953  adenosylhomocysteinase-like [KO:K01251] [EC:3.13.2.1]
            100787210  adenosylhomocysteinase [KO:K01251] [EC:3.13.2.1]
            100500423  1-aminocyclopropane-1-carboxylate synthase 1 [KO:K20772] [EC:4.4.1.14]
            100793020  1-aminocyclopropane-1-carboxylate synthase [KO:K20772] [EC:4.4.1.14]
            100037458  ACS; 1-aminocyclopropane-1-carboxylate synthase [KO:K20772] [EC:4.4.1.14]
            100775969  1-aminocyclopropane-1-carboxylate synthase 1 [KO:K20772] [EC:4.4.1.14]
            547976  ACS1; 1-aminocyclopropane-1-carboxylate synthase [KO:K20772] [EC:4.4.1.14]
            100813347  1-aminocyclopropane-1-carboxylate synthase [KO:K20772] [EC:4.4.1.14]
            100817401  1-aminocyclopropane-1-carboxylate synthase [KO:K20772] [EC:4.4.1.14]
            100803507  1-aminocyclopropane-1-carboxylate synthase 3 [KO:K01762] [EC:4.4.1.14]
            100793912  1-aminocyclopropane-1-carboxylate synthase 3 [KO:K01762] [EC:4.4.1.14]
            100790271  ACS2; 1-aminocyclopropane-1-carboxylate synthase 3 [KO:K01762] [EC:4.4.1.14]
            100783062  1-aminocyclopropane-1-carboxylate synthase 3 [KO:K01762] [EC:4.4.1.14]
            100797692  1-aminocyclopropane-1-carboxylate synthase 7 [KO:K01762] [EC:4.4.1.14]
            100778925  1-aminocyclopropane-1-carboxylate synthase 7 [KO:K01762] [EC:4.4.1.14]
            100789346  1-aminocyclopropane-1-carboxylate synthase 9 [KO:K01762] [EC:4.4.1.14]
            100799562  1-aminocyclopropane-1-carboxylate synthase 7 [KO:K01762] [EC:4.4.1.14]
            100791928  1-aminocyclopropane-1-carboxylate synthase 3 [KO:K01762] [EC:4.4.1.14]
            100791024  1-aminocyclopropane-1-carboxylate synthase 7 [KO:K01762] [EC:4.4.1.14]
            100784455  putative 1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
            100814810  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
            100785514  1-aminocyclopropane-1-carboxylate oxidase 1 [KO:K05933] [EC:1.14.17.4]
            100784459  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
            100793294  1-aminocyclopropane-1-carboxylate oxidase 1 [KO:K05933] [EC:1.14.17.4]
            100796909  1-aminocyclopropane-1-carboxylate oxidase 5-like [KO:K05933] [EC:1.14.17.4]
            100790622  1-aminocyclopropane-1-carboxylate oxidase 5-like protein [KO:K05933] [EC:1.14.17.4]
            100808025  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
            100794816  1-aminocyclopropane-1-carboxylate oxidase 1 [KO:K05933] [EC:1.14.17.4]
            100819184  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
            100807427  1-aminocyclopropane-1-carboxylate oxidase-like [KO:K05933] [EC:1.14.17.4]
            100815336  uncharacterized protein LOC100815336 [KO:K05933] [EC:1.14.17.4]
            100820256  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
            100789627  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
            100792063  1-aminocyclopropane-1-carboxylate oxidase [KO:K05933] [EC:1.14.17.4]
            547546  precursor monofunctional aspartokinase [KO:K00928] [EC:2.7.2.4]
            100792482  aspartokinase 1, chloroplastic [KO:K00928] [EC:2.7.2.4]
            100805860  aspartokinase 2, chloroplastic [KO:K00928] [EC:2.7.2.4]
            100803204  aspartokinase 1, chloroplastic [KO:K00928] [EC:2.7.2.4]
            548017  AK-HSDH; aspartokinase-homoserine dehydrogenase [KO:K12524] [EC:2.7.2.4 1.1.1.3]
            100812202  bifunctional aspartokinase/homoserine dehydrogenase, chloroplastic [KO:K12524] [EC:2.7.2.4 1.1.1.3]
            100793061  aspartate-semialdehyde dehydrogenase [KO:K00133] [EC:1.2.1.11]
            100814757  aspartate-semialdehyde dehydrogenase [KO:K00133] [EC:1.2.1.11]
            548023  CGS2; cystathionine-gamma-synthase [KO:K01739] [EC:2.5.1.48]
            100794584  CGS1; cystathionine gamma-synthase 1, chloroplastic [KO:K01739] [EC:2.5.1.48]
            100783594  branched-chain amino acid aminotransferase 2, chloroplastic [KO:K00826] [EC:2.6.1.42]
            100798328  uncharacterized protein LOC100798328 [KO:K00826] [EC:2.6.1.42]
            100778177  putative branched-chain-amino-acid aminotransferase 7 [KO:K00826] [EC:2.6.1.42]
            100782644  uncharacterized protein LOC100782644 [KO:K00826] [EC:2.6.1.42]
            100775369  putative branched-chain-amino-acid aminotransferase 7 isoform X1 [KO:K00826] [EC:2.6.1.42]
            100818776  branched-chain-amino-acid aminotransferase 2, chloroplastic isoform X2 [KO:K00826] [EC:2.6.1.42]
            100820279  LOW QUALITY PROTEIN: branched-chain-amino-acid aminotransferase 2, chloroplastic [KO:K00826] [EC:2.6.1.42]
            100778723  putative branched-chain-amino-acid aminotransferase 7 [KO:K00826] [EC:2.6.1.42]
            100170733  alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
            100780526  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial isoform X2 [KO:K00827] [EC:2.6.1.44 2.6.1.40]
            100819821  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial isoform X2 [KO:K00827] [EC:2.6.1.44 2.6.1.40]
            100170738  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
            100804017  alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
            100797583  alanine--glyoxylate aminotransferase 2 homolog 3, mitochondrial [KO:K00827] [EC:2.6.1.44 2.6.1.40]
            100775188  glutamate--cysteine ligase, chloroplastic isoform X1 [KO:K01919] [EC:6.3.2.2]
            547545  glutamate--cysteine ligase, chloroplastic isoform X2 [KO:K01919] [EC:6.3.2.2]
            100811211  glutamate--cysteine ligase, chloroplastic [KO:K01919] [EC:6.3.2.2]
            100813419  glutathione synthetase, chloroplastic-like [KO:K21456] [EC:6.3.2.3]
            100784737  glutathione synthetase, chloroplastic isoform X1 [KO:K21456] [EC:6.3.2.3]
            547989  HGS; homoglutathione synthetase [KO:K21456] [EC:6.3.2.3]
            100778473  glutathione synthetase, chloroplastic [KO:K21456] [EC:6.3.2.3]
            547509  AAT; aspartate aminotransferase glyoxysomal isozyme AAT1 precursor [KO:K14454] [EC:2.6.1.1]
            100804162  aspartate aminotransferase [KO:K14454] [EC:2.6.1.1]
            547813  aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
            100814593  aspartate aminotransferase, mitochondrial [KO:K14455] [EC:2.6.1.1]
            100811514  aspartate aminotransferase P2, mitochondrial [KO:K00811] [EC:2.6.1.1]
            547792  aspartate aminotransferase [KO:K00811] [EC:2.6.1.1]
            100798053  thiosulfate/3-mercaptopyruvate sulfurtransferase 2 isoform X1 [KO:K01011] [EC:2.8.1.1 2.8.1.2]
            100796802  thiosulfate/3-mercaptopyruvate sulfurtransferase 2 [KO:K01011] [EC:2.8.1.1 2.8.1.2]
            100818856  L-lactate dehydrogenase B [KO:K00016] [EC:1.1.1.27]
            100814897  L-lactate dehydrogenase B [KO:K00016] [EC:1.1.1.27]
            100803035  L-lactate dehydrogenase A [KO:K00016] [EC:1.1.1.27]
            100815229  bifunctional D-cysteine desulfhydrase/1-aminocyclopropane-1-carboxylate deaminase, mitochondrial isoform X2 [KO:K05396] [EC:4.4.1.15]
            100801680  D-cysteine desulfhydrase 2, mitochondrial isoform X1 [KO:K05396] [EC:4.4.1.15]
            100787528  L-cysteine desulfhydrase [KO:K22207] [EC:4.4.1.28]
            100793745  probable L-cysteine desulfhydrase, chloroplastic [KO:K22207] [EC:4.4.1.28]
            100796732  probable L-cysteine desulfhydrase, chloroplastic [KO:K22207] [EC:4.4.1.28]
            100778443  L-cysteine desulfhydrase [KO:K22207] [EC:4.4.1.28]
            100786129  probable L-cysteine desulfhydrase, chloroplastic [KO:K22207] [EC:4.4.1.28]
            100783188  malate dehydrogenase, cytoplasmic [KO:K00025] [EC:1.1.1.37]
            100811402  malate dehydrogenase, cytoplasmic-like [KO:K00025] [EC:1.1.1.37]
            547963  cytosolic malate dehydrogenase [KO:K00025] [EC:1.1.1.37]
            100777296  malate dehydrogenase, mitochondrial-like [KO:K00026] [EC:1.1.1.37]
            100799793  malate dehydrogenase, glyoxysomal-like [KO:K00026] [EC:1.1.1.37]
            100170735  peroxisomal malate dehydrogenase [KO:K00026] [EC:1.1.1.37]
            606509  MDH-1; malate dehydrogenase [KO:K00026] [EC:1.1.1.37]
            732641  malate dehydrogenase, glyoxysomal [KO:K00026] [EC:1.1.1.37]
            100783173  malate dehydrogenase, chloroplastic [KO:K00026] [EC:1.1.1.37]
            100814078  malate dehydrogenase, chloroplastic-like [KO:K00026] [EC:1.1.1.37]
            100814425  malate dehydrogenase, glyoxysomal [KO:K00026] [EC:1.1.1.37]
            106797956  malate dehydrogenase 1, glyoxysomal-like [KO:K00026] [EC:1.1.1.37]
            100816974  BSAS; uncharacterized protein BSAS [KO:K22846] [EC:2.5.1.144]
            100817949  D-3-phosphoglycerate dehydrogenase 2, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
            100793819  D-3-phosphoglycerate dehydrogenase 2, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
            100819264  D-3-phosphoglycerate dehydrogenase 3, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
            100806526  D-3-phosphoglycerate dehydrogenase 2, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
            100808771  D-3-phosphoglycerate dehydrogenase 1, chloroplastic [KO:K00058] [EC:1.1.1.95 1.1.1.399]
            100798600  phosphoserine aminotransferase 1, chloroplastic [KO:K00831] [EC:2.6.1.52]
            100795286  phosphoserine aminotransferase 2, chloroplastic [KO:K00831] [EC:2.6.1.52]
            100779355  phosphoserine aminotransferase 1, chloroplastic [KO:K00831] [EC:2.6.1.52]
COMPOUND    C00019  S-Adenosyl-L-methionine
            C00021  S-Adenosyl-L-homocysteine
            C00022  Pyruvate
            C00041  L-Alanine
            C00049  L-Aspartate
            C00051  Glutathione
            C00059  Sulfate
            C00065  L-Serine
            C00073  L-Methionine
            C00094  Sulfite
            C00097  L-Cysteine
            C00109  2-Oxobutanoate
            C00155  L-Homocysteine
            C00170  5'-Methylthioadenosine
            C00197  3-Phospho-D-glycerate
            C00263  L-Homoserine
            C00283  Hydrogen sulfide
            C00409  Methanethiol
            C00441  L-Aspartate 4-semialdehyde
            C00491  L-Cystine
            C00506  L-Cysteate
            C00606  3-Sulfino-L-alanine
            C00793  D-Cysteine
            C00957  Mercaptopyruvate
            C00979  O-Acetyl-L-serine
            C01005  O-Phospho-L-serine
            C01077  O-Acetyl-L-homoserine
            C01118  O-Succinyl-L-homoserine
            C01137  S-Adenosylmethioninamine
            C01180  4-Methylthio-2-oxobutanoic acid
            C01234  1-Aminocyclopropane-1-carboxylate
            C01817  L-Homocystine
            C01962  Thiocysteine
            C02218  Dehydroalanine
            C02291  L-Cystathionine
            C02356  (S)-2-Aminobutanoate
            C02989  L-Methionine S-oxide
            C03082  4-Phospho-L-aspartate
            C03089  5-Methylthio-D-ribose
            C03145  N-Formylmethionine
            C03232  3-Phosphonooxypyruvate
            C03539  S-Ribosyl-L-homocysteine
            C04188  S-Methyl-5-thio-D-ribose 1-phosphate
            C04582  S-Methyl-5-thio-D-ribulose 1-phosphate
            C05324  Nicotianamine
            C05524  Aminoacyl-L-methionine
            C05526  S-Glutathionyl-L-cysteine
            C05527  3-Sulfinylpyruvate
            C05528  3-Sulfopyruvate
            C05823  3-Mercaptolactate
            C05824  S-Sulfo-L-cysteine
            C06547  Ethylene
            C08276  3-(Methylthio)propanoate
            C09306  Sulfur dioxide
            C11437  1-Deoxy-D-xylulose 5-phosphate
            C11481  HSO3-
            C11499  (S)-3-Sulfolactate
            C11537  (2R)-3-Sulfolactate
            C15606  1,2-Dihydroxy-5-(methylthio)pent-1-en-3-one
            C15650  2,3-Diketo-5-methylthiopentyl-1-phosphate
            C15651  2-Hydroxy-3-keto-5-methylthiopentenyl-1-phosphate
            C18049  N-Acyl-L-homoserine lactone
            C19787  5'-S-Methyl-5'-thioinosine
            C21015  gamma-L-Glutamyl-L-2-aminobutyrate
            C21016  Ophthalmate
            C22359  S-Methyl-1-thio-D-xylulose 5-phosphate
REFERENCE   PMID:15102328
  AUTHORS   Sekowska A, Denervaud V, Ashida H, Michoud K, Haas D, Yokota A, Danchin A
  TITLE     Bacterial variations on the methionine salvage pathway.
  JOURNAL   BMC Microbiol 4:9 (2004)
            DOI:10.1186/1471-2180-4-9
REFERENCE   PMID:14551435
  AUTHORS   Ashida H, Saito Y, Kojima C, Kobayashi K, Ogasawara N, Yokota A.
  TITLE     A functional link between RuBisCO-like protein of Bacillus and photosynthetic RuBisCO.
  JOURNAL   Science 302:286-90 (2003)
            DOI:10.1126/science.1086997
REFERENCE   PMID:12022921
  AUTHORS   Sekowska A, Danchin A.
  TITLE     The methionine salvage pathway in Bacillus subtilis.
  JOURNAL   BMC Microbiol 2:8 (2002)
            DOI:10.1186/1471-2180-2-8
REFERENCE   PMID:12670965
  AUTHORS   Berger BJ, English S, Chan G, Knodel MH.
  TITLE     Methionine regeneration and aminotransferases in Bacillus subtilis, Bacillus cereus, and Bacillus anthracis.
  JOURNAL   J Bacteriol 185:2418-31 (2003)
            DOI:10.1128/JB.185.8.2418-2431.2003
REFERENCE   PMID:17169919
  AUTHORS   Goyer A, Collakova E, Shachar-Hill Y, Hanson AD
  TITLE     Functional characterization of a methionine gamma-lyase in Arabidopsis and its implication in an alternative to the reverse trans-sulfuration pathway.
  JOURNAL   Plant Cell Physiol 48:232-42 (2007)
            DOI:10.1093/pcp/pcl055
REFERENCE   PMID:17030798
  AUTHORS   Rebeille F, Jabrin S, Bligny R, Loizeau K, Gambonnet B, Van Wilder V, Douce R, Ravanel S
  TITLE     Methionine catabolism in Arabidopsis cells is initiated by a gamma-cleavage process and leads to S-methylcysteine and isoleucine syntheses.
  JOURNAL   Proc Natl Acad Sci U S A 103:15687-92 (2006)
            DOI:10.1073/pnas.0606195103
REFERENCE   PMID:18625006
  AUTHORS   Pirkov I, Norbeck J, Gustafsson L, Albers E
  TITLE     A complete inventory of all enzymes in the eukaryotic methionine salvage pathway.
  JOURNAL   FEBS J 275:4111-20 (2008)
            DOI:10.1111/j.1742-4658.2008.06552.x
REFERENCE   PMID:18391471
  AUTHORS   Ashida H, Saito Y, Kojima C, Yokota A
  TITLE     Enzymatic characterization of 5-methylthioribulose-1-phosphate dehydratase of the methionine salvage pathway in Bacillus subtilis.
  JOURNAL   Biosci Biotechnol Biochem 72:959-67 (2008)
            DOI:10.1271/bbb.70651
REFERENCE   PMID:10613873
  AUTHORS   Kitabatake M, So MW, Tumbula DL, Soll D
  TITLE     Cysteine biosynthesis pathway in the archaeon Methanosarcina barkeri encoded by acquired bacterial genes?
  JOURNAL   J Bacteriol 182:143-5 (2000)
            DOI:10.1128/JB.182.1.143-145.2000
REFERENCE   PMID:12644499
  AUTHORS   Mino K, Ishikawa K
  TITLE     Characterization of a novel thermostable O-acetylserine sulfhydrylase from Aeropyrum pernix K1.
  JOURNAL   J Bacteriol 185:2277-84 (2003)
            DOI:10.1128/JB.185.7.2277-2284.2003
REFERENCE   PMID:18520135
  AUTHORS   Tanabe S
  TITLE     Development of assay methods for endogenous inorganic sulfur compounds and sulfurtransferases and evaluation of the physiological functions of bound sulfur.
  JOURNAL   Yakugaku Zasshi 128:881-900 (2008)
            DOI:10.1248/yakushi.128.881
REFERENCE   
  AUTHORS   Nishizuka Y, Seyama Y, Ikai A, Ishimura Y, Kawaguchi A (eds).
  TITLE     [Cellular Functions and Metabolic Maps] (In Japanese)
  JOURNAL   Tokyo Kagaku Dojin (1997)
REFERENCE   PMID:19270684
  AUTHORS   Gutierrez JA, Crowder T, Rinaldo-Matthis A, Ho MC, Almo SC, Schramm VL
  TITLE     Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing.
  JOURNAL   Nat Chem Biol 5:251-7 (2009)
            DOI:10.1038/nchembio.153
REL_PATHWAY gmx00010  Glycolysis / Gluconeogenesis
            gmx00250  Alanine, aspartate and glutamate metabolism
            gmx00260  Glycine, serine and threonine metabolism
            gmx00290  Valine, leucine and isoleucine biosynthesis
            gmx00430  Taurine and hypotaurine metabolism
            gmx00480  Glutathione metabolism
            gmx00620  Pyruvate metabolism
            gmx00640  Propanoate metabolism
            gmx00770  Pantothenate and CoA biosynthesis
            gmx00900  Terpenoid backbone biosynthesis
            gmx00920  Sulfur metabolism
KO_PATHWAY  ko00270
///
