ReadMe for Chronic protein restriction in mice impacts placental function and maternal body weight before fetal growth. Paula N. Gonzalez; Malgorzata Gasperowicz; Jimena Barbeito-Andrs; Natasha Klenin, James C. Cross; Benedikt Hallgrmsson
2016-15-03

This readme file describes the data files accompanying the above publication.  For any further queries please contact paulan.gonza@gmail.com

The following files are included:

1) "Gonzalez_et_al_Dam.txt"
This file contains the weight of the dams at each DPC before and after dissection.

2) "Gonzalez_et_al_Embryo_Placenta.txt"
This file contains the weight of embryos and placentas at the three DPC sampled

3) "Gonzalez_et_al_Morphometric_skull.txt"
This file conains the raw coordinates of landmarks of the skull and the centroid size for specimens at 17.5 and 18.5DPC

4) "Gonzalez_et_al_Brain_size.txt"
This file lists the centroid size of the brain for specimens at 18.5DPC

5) "Gonzalez_et_al_genes.txt"
This file contains the gene expression in the placentas of the low protein groups in relation to control placentas. Data are expresses as fold changes.

6) "Pcdh12 area E10 E17 E18 data.xls"
This file contains the area of Pchd12 expression at the three age stages analyzed.

7) "Pcdh12 area E10 E17 E18 description.docx" 
This file describes the variables contained in "Pcdh12 area E10 E17 E18 data.xls"

8) "Placenta layers areas E10 E17 E18 data.xls"
This file contains the area of the three layers of the placenta at the three age stages analyzed.

9) "Placenta layers areas E10 E17 E18 description.docx"
This file describes the variables contained in "Placenta layers areas E10 E17 E18 data.xls"

Variables in data files>
Weight-1> Maternal weight at each DPC before dissecting the uterus
Weight-2> Maternal weight at each DPC after dissecting the uterus
DPC Days post conception
DamID> Number that identifies each dam. The first number represents the cage and the second number the females in that cage.
SpecimenID> Identification of each embryo, the first two numbers correspond to the mather and the last number corresponds to the embryos in the litter.
EmbryoW(g)> Weight of embryos in grams
PlacentaW(g)> Placental weight in grams
 

