## New Classes

 * [MONDO:0030923](http://purl.obolibrary.org/obo/MONDO_0030923) frontotemporal dementia and/or amyotrophic lateral sclerosis
 * [MONDO:0035112](http://purl.obolibrary.org/obo/MONDO_0035112) acute myeloid leukemia with BCR-ABL1
 * [MONDO:0100237](http://purl.obolibrary.org/obo/MONDO_0100237) inherited cutis laxa
 * [MONDO:0100238](http://purl.obolibrary.org/obo/MONDO_0100238) inherited Fanconi renotubular syndrome
 * [MONDO:0100239](http://purl.obolibrary.org/obo/MONDO_0100239) inherited hypertrophic pyloric stenosis
 * [MONDO:0100240](http://purl.obolibrary.org/obo/MONDO_0100240) inherited thrombophilia
 * [MONDO:0100241](http://purl.obolibrary.org/obo/MONDO_0100241) inherited thrombocytopenia
 * [MONDO:0100242](http://purl.obolibrary.org/obo/MONDO_0100242) glioma susceptibility
 * [MONDO:0100243](http://purl.obolibrary.org/obo/MONDO_0100243) inherited paroxysmal nocturnal hemoglobinuria
 * [MONDO:0100244](http://purl.obolibrary.org/obo/MONDO_0100244) paroxysmal nocturnal hemoglobinuria
 * [MONDO:0100245](http://purl.obolibrary.org/obo/MONDO_0100245) acquired paroxysmal nocturnal hemoglobinuria
 * [MONDO:0100246](http://purl.obolibrary.org/obo/MONDO_0100246) migraine with or without aura, susceptibility to
 * [MONDO:0100247](http://purl.obolibrary.org/obo/MONDO_0100247) multiple congenital anomalies-hypotonia-seizures syndrome
 * [MONDO:0100248](http://purl.obolibrary.org/obo/MONDO_0100248) rapidly progressive primary central nervous system vasculitis
 * [MONDO:0100249](http://purl.obolibrary.org/obo/MONDO_0100249) 46,XX testicular disorder of sex development
 * [MONDO:0100250](http://purl.obolibrary.org/obo/MONDO_0100250) 46,XX sex reversal 1
 * [MONDO:0100251](http://purl.obolibrary.org/obo/MONDO_0100251) familial hyperphosphatemic tumoral calcinosis/hyperphosphatemic hyperostosis syndrome
 * [MONDO:0100252](http://purl.obolibrary.org/obo/MONDO_0100252) tumoral calcinosis, hyperphosphatemic, familial, 1
 * [MONDO:0100253](http://purl.obolibrary.org/obo/MONDO_0100253) Roberts-SC phocomelia syndrome
 * [MONDO:0100255](http://purl.obolibrary.org/obo/MONDO_0100255) adenosine kinase deficiency
 * [MONDO:0100280](http://purl.obolibrary.org/obo/MONDO_0100280) Waldenstrom macroglobulinemia
 * [MONDO:0100281](http://purl.obolibrary.org/obo/MONDO_0100281) macroglobulinemia, Waldenstrom, 1
 * [MONDO:0100282](http://purl.obolibrary.org/obo/MONDO_0100282) SC phocomelia syndrome
 * [MONDO:0100284](http://purl.obolibrary.org/obo/MONDO_0100284) X-linked intellectual disability
 * [MONDO:0100285](http://purl.obolibrary.org/obo/MONDO_0100285) extrahepatic biliary atresia
 * [MONDO:0100286](http://purl.obolibrary.org/obo/MONDO_0100286) respiratory syncytial virus bronchiolitis
 * [MONDO:0100288](http://purl.obolibrary.org/obo/MONDO_0100288) enhanced S-cone syndrome
 * [MONDO:0100289](http://purl.obolibrary.org/obo/MONDO_0100289) Goldmann-Favre syndrome

## Obsoletions

 * [MONDO:0000834](http://purl.obolibrary.org/obo/MONDO_0000834) bone deterioration disease --> obsolete bone deterioration disease
 * [MONDO:0007926](http://purl.obolibrary.org/obo/MONDO_0007926) Waldenstrom macroglobulinemia --> obsolete Waldenstrom macroglobulinemia
 * [MONDO:0008112](http://purl.obolibrary.org/obo/MONDO_0008112) Goldenhar syndrome --> obsolete Goldenhar syndrome
 * [MONDO:0008220](http://purl.obolibrary.org/obo/MONDO_0008220) pepsinogen 3, group 1 --> obsolete pepsinogen 3, group 1
 * [MONDO:0008897](http://purl.obolibrary.org/obo/MONDO_0008897) hyperphosphatemic familial tumoral calcinosis --> obsolete tumoral calcinosis, hyperphosphatemic, familial, 1
 * [MONDO:0009989](http://purl.obolibrary.org/obo/MONDO_0009989) enhanced S-cone syndrome --> obsolete enhanced S-cone syndrome
 * [MONDO:0010009](http://purl.obolibrary.org/obo/MONDO_0010009) SC phocomelia syndrome --> obsolete SC phocomelia syndrome
 * [MONDO:0010303](http://purl.obolibrary.org/obo/MONDO_0010303) colobomatous microphthalmia --> obsolete colobomatous microphthalmia
 * [MONDO:0010372](http://purl.obolibrary.org/obo/MONDO_0010372) Clark-Baraitser syndrome --> obsolete Clark-Baraitser syndrome
 * [MONDO:0010766](http://purl.obolibrary.org/obo/MONDO_0010766) 46,XX testicular disorder of sex development --> obsolete 46,XX sex reversal 1
 * [MONDO:0011204](http://purl.obolibrary.org/obo/MONDO_0011204) cerebellar degeneration-related autoantigen 3 --> obsolete cerebellar degeneration-related autoantigen 3
 * [MONDO:0011623](http://purl.obolibrary.org/obo/MONDO_0011623) spinocerebellar ataxia, autosomal recessive 1 --> obsolete spinocerebellar ataxia, autosomal recessive 1
 * [MONDO:0013676](http://purl.obolibrary.org/obo/MONDO_0013676) hypermethioninemia due to adenosine kinase deficiency --> obsolete hypermethioninemia due to adenosine kinase deficiency
 * [MONDO:0013861](http://purl.obolibrary.org/obo/MONDO_0013861) amyotrophic lateral sclerosis type 17 --> obsolete amyotrophic lateral sclerosis type 17
 * [MONDO:0014655](http://purl.obolibrary.org/obo/MONDO_0014655) Bethlem myopathy 2 --> obsolete Bethlem myopathy 2
 * [MONDO:0016640](http://purl.obolibrary.org/obo/MONDO_0016640) fibrous dysplasia of bone --> obsolete fibrous dysplasia of bone
 * [MONDO:0017911](http://purl.obolibrary.org/obo/MONDO_0017911) cleft lip/palate-ectodermal dysplasia syndrome --> obsolete cleft lip/palate-ectodermal dysplasia syndrome
 * [MONDO:0018641](http://purl.obolibrary.org/obo/MONDO_0018641) paroxysmal nocturnal hemoglobinuria --> obsolete paroxysmal nocturnal hemoglobinuria
 * [MONDO:0023191](http://purl.obolibrary.org/obo/MONDO_0023191) Freire-Maia odontotrichomelic syndrome --> obsolete Freire-Maia odontotrichomelic syndrome
 * [MONDO:0033939](http://purl.obolibrary.org/obo/MONDO_0033939) hypohidrosis-electrolyte imbalance-lacrimal gland dysfunction-ichthyosis-xerostomia syndrome --> obsolete hypohidrosis-electrolyte imbalance-lacrimal gland dysfunction-ichthyosis-xerostomia syndrome
 * [MONDO:0043181](http://purl.obolibrary.org/obo/MONDO_0043181) refsum disease with increased pipecolic acidemia --> obsolete Refsum disease with increased pipecolic acidemia

## Renaming

 * [MONDO:0000834](http://purl.obolibrary.org/obo/MONDO_0000834) bone deterioration disease --> obsolete bone deterioration disease
 * [MONDO:0003321](http://purl.obolibrary.org/obo/MONDO_0003321) hereditary Wilms' tumor --> hereditary Wilms tumor
 * [MONDO:0005578](http://purl.obolibrary.org/obo/MONDO_0005578) arthritis --> arthritic joint disease
 * [MONDO:0006664](http://purl.obolibrary.org/obo/MONDO_0006664) atrial heart septal defect --> atrial septal defect
 * [MONDO:0007105](http://purl.obolibrary.org/obo/MONDO_0007105) frontotemporal dementia with motor neuron disease 1 --> frontotemporal dementia and/or amyotrophic lateral sclerosis 1
 * [MONDO:0007172](http://purl.obolibrary.org/obo/MONDO_0007172) atrial heart septal defect 1 --> atrial septal defect 1
 * [MONDO:0007173](http://purl.obolibrary.org/obo/MONDO_0007173) atrial heart septal defect 7 --> atrial septal defect 7
 * [MONDO:0007319](http://purl.obolibrary.org/obo/MONDO_0007319) familial calcium pyrophosphate deposition --> chondrocalcinosis 2
 * [MONDO:0007399](http://purl.obolibrary.org/obo/MONDO_0007399) craniosynostosis 1 --> TWIST1-related craniosynostosis
 * [MONDO:0007681](http://purl.obolibrary.org/obo/MONDO_0007681) familial multinodular goiter --> goiter, multinodular 1, with or without Sertoli-Leydig cell tumors
 * [MONDO:0007768](http://purl.obolibrary.org/obo/MONDO_0007768) hyperparathyroidism-jaw tumor syndrome --> hyperparathyroidism 2 with jaw tumors
 * [MONDO:0007926](http://purl.obolibrary.org/obo/MONDO_0007926) Waldenstrom macroglobulinemia --> obsolete Waldenstrom macroglobulinemia
 * [MONDO:0008050](http://purl.obolibrary.org/obo/MONDO_0008050) Laing early-onset distal myopathy --> MYH7-related skeletal myopathy
 * [MONDO:0008112](http://purl.obolibrary.org/obo/MONDO_0008112) Goldenhar syndrome --> obsolete Goldenhar syndrome
 * [MONDO:0008220](http://purl.obolibrary.org/obo/MONDO_0008220) pepsinogen 3, group 1 --> obsolete pepsinogen 3, group 1
 * [MONDO:0008226](http://purl.obolibrary.org/obo/MONDO_0008226) aggressive periodontitis --> periodontitis, aggressive 1
 * [MONDO:0008355](http://purl.obolibrary.org/obo/MONDO_0008355) IHPS1 --> pyloric stenosis, infantile hypertrophic, 1
 * [MONDO:0008473](http://purl.obolibrary.org/obo/MONDO_0008473) spondyloepiphyseal dysplasia, Maroteaux type --> spondyloepimetaphyseal dysplasia, Maroteaux type
 * [MONDO:0008494](http://purl.obolibrary.org/obo/MONDO_0008494) hereditary cryohydrocytosis with normal stomatin --> cryohydrocytosis
 * [MONDO:0008679](http://purl.obolibrary.org/obo/MONDO_0008679) Wilms tumor type 1 --> Wilms tumor 1
 * [MONDO:0008710](http://purl.obolibrary.org/obo/MONDO_0008710) Carpenter syndrome 1 --> RAB23-related Carpenter syndrome
 * [MONDO:0008897](http://purl.obolibrary.org/obo/MONDO_0008897) hyperphosphatemic familial tumoral calcinosis --> obsolete tumoral calcinosis, hyperphosphatemic, familial, 1
 * [MONDO:0009151](http://purl.obolibrary.org/obo/MONDO_0009151) Zlotogora-Ogur syndrome --> cleft lip/palate-ectodermal dysplasia syndrome
 * [MONDO:0009989](http://purl.obolibrary.org/obo/MONDO_0009989) enhanced S-cone syndrome --> obsolete enhanced S-cone syndrome
 * [MONDO:0010009](http://purl.obolibrary.org/obo/MONDO_0010009) SC phocomelia syndrome --> obsolete SC phocomelia syndrome
 * [MONDO:0010290](http://purl.obolibrary.org/obo/MONDO_0010290) MNG2 --> goiter, multinodular 2
 * [MONDO:0010296](http://purl.obolibrary.org/obo/MONDO_0010296) AGMX2 --> immunodeficiency 61
 * [MONDO:0010303](http://purl.obolibrary.org/obo/MONDO_0010303) colobomatous microphthalmia --> obsolete colobomatous microphthalmia
 * [MONDO:0010372](http://purl.obolibrary.org/obo/MONDO_0010372) Clark-Baraitser syndrome --> obsolete Clark-Baraitser syndrome
 * [MONDO:0010411](http://purl.obolibrary.org/obo/MONDO_0010411) IHPS4 --> pyloric stenosis, infantile hypertrophic, 4
 * [MONDO:0010728](http://purl.obolibrary.org/obo/MONDO_0010728) scarf syndrome --> SCARF syndrome
 * [MONDO:0010758](http://purl.obolibrary.org/obo/MONDO_0010758) intellectual disability-developmental delay-contractures syndrome --> Wieacker-Wolff, X-linked recessive
 * [MONDO:0010766](http://purl.obolibrary.org/obo/MONDO_0010766) 46,XX testicular disorder of sex development --> obsolete 46,XX sex reversal 1
 * [MONDO:0010917](http://purl.obolibrary.org/obo/MONDO_0010917) CCAL1 --> chondrocalcinosis 1
 * [MONDO:0010936](http://purl.obolibrary.org/obo/MONDO_0010936) frontotemporal dementia, chromosome 3-linked --> frontotemporal dementia and/or amyotrophic lateral sclerosis 7
 * [MONDO:0010997](http://purl.obolibrary.org/obo/MONDO_0010997) classic progressive supranuclear palsy syndrome --> supranuclear palsy, progressive, 1
 * [MONDO:0011204](http://purl.obolibrary.org/obo/MONDO_0011204) cerebellar degeneration-related autoantigen 3 --> obsolete cerebellar degeneration-related autoantigen 3
 * [MONDO:0011589](http://purl.obolibrary.org/obo/MONDO_0011589) MCOPCB2 --> microphthalmia with coloboma 2
 * [MONDO:0011623](http://purl.obolibrary.org/obo/MONDO_0011623) spinocerebellar ataxia, autosomal recessive 1 --> obsolete spinocerebellar ataxia, autosomal recessive 1
 * [MONDO:0011635](http://purl.obolibrary.org/obo/MONDO_0011635) MNG3 --> goiter, multinodular 3
 * [MONDO:0011801](http://purl.obolibrary.org/obo/MONDO_0011801) spinocerebellar ataxia type 1 with axonal neuropathy --> spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 1
 * [MONDO:0011847](http://purl.obolibrary.org/obo/MONDO_0011847) migraine without aura --> migraine without aura, susceptibility to, 4
 * [MONDO:0011938](http://purl.obolibrary.org/obo/MONDO_0011938) atrial heart septal defect 2 --> atrial septal defect 2
 * [MONDO:0012278](http://purl.obolibrary.org/obo/MONDO_0012278) PSNP2 --> supranuclear palsy, progressive, 2
 * [MONDO:0012292](http://purl.obolibrary.org/obo/MONDO_0012292) hepatitis c virus, susceptibility to --> hepatitis C virus, susceptibility to
 * [MONDO:0012406](http://purl.obolibrary.org/obo/MONDO_0012406) HRPT3 --> hyperparathyroidism 3
 * [MONDO:0012457](http://purl.obolibrary.org/obo/MONDO_0012457) IHPS2 --> pyloric stenosis, infantile hypertrophic, 2
 * [MONDO:0012491](http://purl.obolibrary.org/obo/MONDO_0012491) WM2 --> macroglobulinemia, Waldenstrom, 2
 * [MONDO:0012551](http://purl.obolibrary.org/obo/MONDO_0012551) AA2 --> alopecia areata 2
 * [MONDO:0012561](http://purl.obolibrary.org/obo/MONDO_0012561) congenital anomalies of kidney and urinary tract 1, susceptibility to --> congenital anomalies of kidney and urinary tract 1
 * [MONDO:0012576](http://purl.obolibrary.org/obo/MONDO_0012576) PSNP3 --> supranuclear palsy, progressive, 3
 * [MONDO:0012654](http://purl.obolibrary.org/obo/MONDO_0012654) atrial heart septal defect 4 --> atrial septal defect 4
 * [MONDO:0012715](http://purl.obolibrary.org/obo/MONDO_0012715) MGR12 --> migraine with or without aura, susceptibility to, 12
 * [MONDO:0012785](http://purl.obolibrary.org/obo/MONDO_0012785) infantile hypertrophic pyloric stenosis type 3 --> pyloric stenosis, infantile hypertrophic, 3
 * [MONDO:0012922](http://purl.obolibrary.org/obo/MONDO_0012922) infantile hypertrophic pyloric stenosis type 5 --> pyloric stenosis, infantile hypertrophic, 5
 * [MONDO:0013011](http://purl.obolibrary.org/obo/MONDO_0013011) atrial heart septal defect 5 --> atrial septal defect 5
 * [MONDO:0013123](http://purl.obolibrary.org/obo/MONDO_0013123) atrial heart septal defect 6 --> atrial septal defect 6
 * [MONDO:0013138](http://purl.obolibrary.org/obo/MONDO_0013138) BRV2 --> vertigo, benign recurrent, 2
 * [MONDO:0013501](http://purl.obolibrary.org/obo/MONDO_0013501) amyotrophic lateral sclerosis type 14 --> frontotemporal dementia and/or amyotrophic lateral sclerosis 6
 * [MONDO:0013567](http://purl.obolibrary.org/obo/MONDO_0013567) atrial heart septal defect 3 --> atrial septal defect 3
 * [MONDO:0013676](http://purl.obolibrary.org/obo/MONDO_0013676) hypermethioninemia due to adenosine kinase deficiency --> obsolete hypermethioninemia due to adenosine kinase deficiency
 * [MONDO:0013750](http://purl.obolibrary.org/obo/MONDO_0013750) atrial heart septal defect 8 --> atrial septal defect 8
 * [MONDO:0013770](http://purl.obolibrary.org/obo/MONDO_0013770) atrial heart septal defect 9 --> atrial septal defect 9
 * [MONDO:0013861](http://purl.obolibrary.org/obo/MONDO_0013861) amyotrophic lateral sclerosis type 17 --> obsolete amyotrophic lateral sclerosis type 17
 * [MONDO:0013998](http://purl.obolibrary.org/obo/MONDO_0013998) Carpenter syndrome 2 --> MEGF8-related Carpenter syndrome
 * [MONDO:0014128](http://purl.obolibrary.org/obo/MONDO_0014128) craniosynostosis 3 --> TCF12-related craniosynostosis
 * [MONDO:0014395](http://purl.obolibrary.org/obo/MONDO_0014395) FTDALS2 --> frontotemporal dementia and/or amyotrophic lateral sclerosis 2
 * [MONDO:0014640](http://purl.obolibrary.org/obo/MONDO_0014640) FTDALS3 --> frontotemporal dementia and/or amyotrophic lateral sclerosis 3
 * [MONDO:0014641](http://purl.obolibrary.org/obo/MONDO_0014641) FTDALS4 --> frontotemporal dementia and/or amyotrophic lateral sclerosis 4
 * [MONDO:0014655](http://purl.obolibrary.org/obo/MONDO_0014655) Bethlem myopathy 2 --> obsolete Bethlem myopathy 2
 * [MONDO:0014659](http://purl.obolibrary.org/obo/MONDO_0014659) fever-associated acute infantile liver failure syndrome --> infantile liver failure syndrome 2
 * [MONDO:0016640](http://purl.obolibrary.org/obo/MONDO_0016640) fibrous dysplasia of bone --> obsolete fibrous dysplasia of bone
 * [MONDO:0017241](http://purl.obolibrary.org/obo/MONDO_0017241) severe intellectual disability and progressive spastic paraplegia --> AP4-related intellectual disability and spastic paraplegia
 * [MONDO:0017911](http://purl.obolibrary.org/obo/MONDO_0017911) cleft lip/palate-ectodermal dysplasia syndrome --> obsolete cleft lip/palate-ectodermal dysplasia syndrome
 * [MONDO:0018641](http://purl.obolibrary.org/obo/MONDO_0018641) paroxysmal nocturnal hemoglobinuria --> obsolete paroxysmal nocturnal hemoglobinuria
 * [MONDO:0018828](http://purl.obolibrary.org/obo/MONDO_0018828) UPS18 deficiency --> pseudo-TORCH syndrome 2
 * [MONDO:0018996](http://purl.obolibrary.org/obo/MONDO_0018996) spinocerebellar ataxia with axonal neuropathy type 2 --> spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2
 * [MONDO:0019567](http://purl.obolibrary.org/obo/MONDO_0019567) Ehlers-Danlos syndrome type 1 --> Ehlers-Danlos syndrome, classic type, 1
 * [MONDO:0019568](http://purl.obolibrary.org/obo/MONDO_0019568) Ehlers-Danlos syndrome type 2 --> Ehlers-Danlos syndrome, classic type, 2
 * [MONDO:0022948](http://purl.obolibrary.org/obo/MONDO_0022948) deal barratt dillon syndrome --> Deal Barratt Dillon syndrome
 * [MONDO:0023191](http://purl.obolibrary.org/obo/MONDO_0023191) Freire-Maia odontotrichomelic syndrome --> obsolete Freire-Maia odontotrichomelic syndrome
 * [MONDO:0024525](http://purl.obolibrary.org/obo/MONDO_0024525) FRTS1 --> Fanconi renotubular syndrome 1
 * [MONDO:0024549](http://purl.obolibrary.org/obo/MONDO_0024549) MCOPCB1 --> microphthalmia with coloboma 1
 * [MONDO:0027451](http://purl.obolibrary.org/obo/MONDO_0027451) autosomal recessive cutis laxa type 2d --> autosomal recessive cutis laxa type 2D
 * [MONDO:0027462](http://purl.obolibrary.org/obo/MONDO_0027462) autosomal recessive cutis laxa type 2c --> autosomal recessive cutis laxa type 2C
 * [MONDO:0027676](http://purl.obolibrary.org/obo/MONDO_0027676) congenital anomalies of kidney and urinary tract type 2 --> congenital anomalies of kidney and urinary tract 2
 * [MONDO:0030044](http://purl.obolibrary.org/obo/MONDO_0030044) pseudo-torch syndrome 3 --> pseudo-TORCH syndrome 3
 * [MONDO:0030056](http://purl.obolibrary.org/obo/MONDO_0030056) fanconi renotubular syndrome 5 --> Fanconi renotubular syndrome 5
 * [MONDO:0033939](http://purl.obolibrary.org/obo/MONDO_0033939) hypohidrosis-electrolyte imbalance-lacrimal gland dysfunction-ichthyosis-xerostomia syndrome --> obsolete hypohidrosis-electrolyte imbalance-lacrimal gland dysfunction-ichthyosis-xerostomia syndrome
 * [MONDO:0034022](http://purl.obolibrary.org/obo/MONDO_0034022) myopathic Ehlers-Danlos syndrome --> Bethlem myopathy 2
 * [MONDO:0043181](http://purl.obolibrary.org/obo/MONDO_0043181) refsum disease with increased pipecolic acidemia --> obsolete Refsum disease with increased pipecolic acidemia
 * [MONDO:0060564](http://purl.obolibrary.org/obo/MONDO_0060564) helix syndrome --> HELIX syndrome

