DFS								DSS
				HR (95% CI)	HR	2.5% CI	97.5% CI	Per-term P-value	Per-model P-value	C-index	N	HR (95% CI)	HR	2.5% CI	97.5% CI	Per-term P-value	Per-model P-value	C-index	N
Model type	Term	Ref level	Level
univariate	treatment							0.03	0.03	0.60	75					0.11	0.11	0.57	75
		observation	chemotherapy		0.52	0.28	0.96						0.60	0.31	1.13
	age				0.99	0.96	1.03	0.77	0.77	0.49	75		0.99	0.95	1.02	0.46	0.46	0.53	75
	sex							0.80	0.80	0.51	75					0.36	0.36	0.54	75
		male	female		1.08	0.58	2.01						1.35	0.71	2.54
	cancer type							0.77	0.77	0.51	75					0.98	0.98	0.48	75
		colon	rectum		1.10	0.57	2.13						1.01	0.51	1.99
	type of surgery							0.86	0.86	0.51	75					1.00	1.00	0.53	75
		resection	colectomy		0.79	0.23	2.71						1.03	0.30	3.56
			hemicolectomy		0.85	0.45	1.60						1.02	0.52	1.97
	CIC in tumour tissue							0.92	0.92	0.52	72					0.50	0.50	0.54	72
		T-CIC=0	T-CIC>0		1.03	0.55	1.94						1.26	0.64	2.44
	CIC in invasive front tissue							0.02	0.02	0.60	69					0.04	0.04	0.59	69
		S-CIC=0	S-CIC>0		2.17	1.08	4.36						2.07	1.00	4.29
	CIC in normal tissue							0.50	0.50	0.52	65					0.75	0.75	0.51	65
		N-CIC=0	N-CIC>0		0.68	0.21	2.22						0.83	0.25	2.72
multivariate									0.01	0.69	69						0.06	0.67	69
	treatment							0.003								0.02
		observation	chemotherapy		0.36	0.18	0.71						0.43	0.21	0.87
	age				1.01	0.97	1.04	0.76					0.99	0.95	1.02	0.49
	sex							0.72								0.28
		male	female		1.13	0.59	2.18						1.47	0.73	2.95
	cancer type							0.32								0.83
		colon	rectum		1.45	0.70	2.97						1.09	0.52	2.25
	CIC in invasive front tissue							0.004								0.02
		S-CIC=0	S-CIC>0		2.67	1.31	5.43						2.33	1.12	4.87