Three and a half months old, Lean origin, properly vaccinated for his age, with no relevant medical history.
Controlled pregnancy in Spain, uneventful pregnancy.
The family history included healthy, non-consanguineous parents; two healthy three- and ten-year-old sisters and five male siblings who died before the year of life, all of them complicated by a respiratory condition.
The infant presents an adequate gain and has not presented infections since birth.
In their reference hospital, they referred him for study because of the family history of male children who died early.
In our center we performed a blood test showing absolute figures of immunoglobulins and predominance of subunit studies with humoral analysis: IgG 153 mg/dl, IgA 23 mg/dl, IgM 17 mg/dl and IgE 10.8 mg/dl absolute lymphocytes decrease.
Treatment was initiated with monthly intravenous gammaglobulin (400 mg/kg) and complete vaccination (including antipneumococci), with satisfactory evolution.
Currently she is six years old, she is under treatment with monthly gammaglobulin and has not presented complications or intercurrent processes, presenting a good staturoptic curve.
