85 year old patient treated with moxifloxacin for a respiratory infection who was admitted for vomiting, diarrhea and fever of 38.5o C; with hypoalbuminemia of 2.62 g/dL, serum creatinine (Cultck-mL) calculated around 38
He was diagnosed with severe and complicated ICD without abdominal disfunction meeting the criteria established in the guidelines for the diagnosis, treatment and prevention of ICD3 and was prescribed intravenous metronidazole 500 mg three times a day plus oral vancomycin 500 mg.
After 3 days of treatment vancomycin trough plasma levels of 5.77 μg/mL were detected.
This value increases to 10.81 μg/mL on the sixth day of treatment.
After 7 days, after resolution of the diarrheal condition and a negative result of toxin in faeces, antibiotics were suspended.
