A previously healthy 2-year-old boy.
It began with generalized dermatosis with maximum lesion in the umbilical region, limbs and genitals, characterized by blisters, some denuded with easy bleeding, without mucosal involvement or fever.
Bullous impetus was diagnosed and topical and systemic antibiotic therapy was indicated without clinical improvement.
Elevated liver function tests were performed.
Histological and immunohistochemical study of the lesions and perilesional skin confirmed pemphigus vulgaris.
Corticosteroid and immunomodulator treatment was started with good response.
