A 42-year-old male, former smoker, started treatment with allopurinol 14 days before.
She was admitted to the hospital for investigation of probable interstitial pneumopathy.
During the admission, the patient presented cutaneous eruption, initially diagnosed with polymorphous erythema, treated with methylprednisolone; the diagnosis and tachycardia unfavourably progressed with worsening of cutaneous lesions, affecting 65% of the body surface.
The patient had mucosal healing favorable after treatment with cyclosporine A, and was discharged seven days after admission, with skin reepithelialization in most initial lesions and significant improvement of the condition.
