Motif ID: ZNF8

Z-value: 0.251


Transcription factors associated with ZNF8:

Gene SymbolEntrez IDGene Name
ZNF8 ENSG00000083842.8 ZNF8
ZNF8 ENSG00000273439.1 ZNF8

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZNF8hg19_v2_chr19_+_58790314_587903580.561.1e-01Click!


Activity profile for motif ZNF8.

activity profile for motif ZNF8


Sorted Z-values histogram for motif ZNF8

Sorted Z-values for motif ZNF8



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF8

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_13043697 0.330 ENST00000378825.3
 CCDC3
coiled-coil domain containing 3
chrX_+_1387693 0.218 ENST00000381529.3
ENST00000432318.2
ENST00000361536.3
ENST00000501036.2
ENST00000381524.3
ENST00000412290.1
 CSF2RA





colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)





chr6_-_26056695 0.216 ENST00000343677.2
 HIST1H1C
histone cluster 1, H1c
chr14_+_105941118 0.203 ENST00000550577.1
ENST00000538259.2
 CRIP2

cysteine-rich protein 2

chr19_+_35739897 0.201 ENST00000605618.1
ENST00000427250.1
ENST00000601623.1
 LSR


lipolysis stimulated lipoprotein receptor


chr11_-_58345569 0.188 ENST00000528954.1
ENST00000528489.1
 LPXN

leupaxin

chr2_+_169926047 0.184 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
 DHRS9


dehydrogenase/reductase (SDR family) member 9


chr19_+_35739782 0.181 ENST00000347609.4
 LSR
lipolysis stimulated lipoprotein receptor
chr5_+_89854595 0.157 ENST00000405460.2
 GPR98
G protein-coupled receptor 98
chr4_+_186347388 0.116 ENST00000511138.1
ENST00000511581.1
 C4orf47

chromosome 4 open reading frame 47

chr2_+_240323439 0.107 ENST00000428471.1
ENST00000413029.1
 AC062017.1

Uncharacterized protein

chr8_+_38244638 0.073 ENST00000526356.1
 LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr4_-_52904425 0.071 ENST00000535450.1
 SGCB
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr5_+_134210035 0.070 ENST00000506916.1
 TXNDC15
thioredoxin domain containing 15
chr6_+_53659746 0.062 ENST00000370888.1
 LRRC1
leucine rich repeat containing 1
chr6_+_31939608 0.056 ENST00000375331.2
ENST00000375333.2
 STK19

serine/threonine kinase 19

chr7_+_1748798 0.056 ENST00000561626.1
 ELFN1
extracellular leucine-rich repeat and fibronectin type III domain containing 1
chr17_-_27169745 0.054 ENST00000583307.1
ENST00000581229.1
ENST00000582266.1
ENST00000577376.1
ENST00000577682.1
ENST00000581381.1
ENST00000341217.5
ENST00000581407.1
ENST00000583522.1
 FAM222B








family with sequence similarity 222, member B








chr17_+_34136459 0.052 ENST00000588240.1
ENST00000590273.1
ENST00000588441.1
ENST00000587272.1
ENST00000592237.1
ENST00000311979.3
 TAF15





TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa





chr1_+_214161272 0.049 ENST00000498508.2
ENST00000366958.4
 PROX1

prospero homeobox 1

chr10_-_1034237 0.049 ENST00000381466.1
 AL359878.1
Uncharacterized protein
chr17_+_75181292 0.045 ENST00000431431.2
 SEC14L1
SEC14-like 1 (S. cerevisiae)
chr9_+_1050331 0.043 ENST00000382255.3
ENST00000382251.3
ENST00000412350.2
 DMRT2


doublesex and mab-3 related transcription factor 2


chr6_+_106959718 0.042 ENST00000369066.3
 AIM1
absent in melanoma 1
chr2_-_240322685 0.041 ENST00000544989.1
 HDAC4
histone deacetylase 4
chr2_-_240322643 0.040 ENST00000345617.3
 HDAC4
histone deacetylase 4
chr17_+_48585794 0.038 ENST00000576179.1
ENST00000419930.1
 MYCBPAP

MYCBP associated protein

chr19_+_52074502 0.035 ENST00000545217.1
ENST00000262259.2
ENST00000596504.1
 ZNF175


zinc finger protein 175


chr11_+_46402583 0.032 ENST00000359803.3
 MDK
midkine (neurite growth-promoting factor 2)
chr4_+_24797085 0.032 ENST00000382120.3
 SOD3
superoxide dismutase 3, extracellular
chr2_-_105946491 0.032 ENST00000393359.2
 TGFBRAP1
transforming growth factor, beta receptor associated protein 1
chr6_+_88117683 0.027 ENST00000369562.4
 C6ORF165
UPF0704 protein C6orf165
chr12_+_52463751 0.026 ENST00000336854.4
ENST00000550604.1
ENST00000553049.1
ENST00000548915.1
 C12orf44



chromosome 12 open reading frame 44



chr2_+_198365122 0.026 ENST00000604458.1
 HSPE1-MOB4
HSPE1-MOB4 readthrough
chr6_+_18155560 0.023 ENST00000546309.2
ENST00000388870.2
ENST00000397244.1
 KDM1B


lysine (K)-specific demethylase 1B


chr2_-_172290482 0.020 ENST00000442541.1
ENST00000392599.2
ENST00000375258.4
 METTL8


methyltransferase like 8


chr1_+_186344883 0.020 ENST00000367470.3
 C1orf27
chromosome 1 open reading frame 27
chr1_-_55266926 0.020 ENST00000371276.4
 TTC22
tetratricopeptide repeat domain 22
chr17_-_45908875 0.019 ENST00000351111.2
ENST00000414011.1
 MRPL10

mitochondrial ribosomal protein L10

chr6_+_29691056 0.018 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
 HLA-F


major histocompatibility complex, class I, F


chr8_-_61429315 0.017 ENST00000530725.1
ENST00000532232.1
 RP11-163N6.2

RP11-163N6.2

chr11_+_46402482 0.016 ENST00000441869.1
 MDK
midkine (neurite growth-promoting factor 2)
chr1_+_186344945 0.015 ENST00000419367.3
ENST00000287859.6
 C1orf27

chromosome 1 open reading frame 27

chr5_-_43515125 0.015 ENST00000509489.1
 C5orf34
chromosome 5 open reading frame 34
chr6_+_29691198 0.015 ENST00000440587.2
ENST00000434407.2
 HLA-F

major histocompatibility complex, class I, F

chr5_+_102455968 0.014 ENST00000358359.3
 PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr5_-_137911049 0.013 ENST00000297185.3
 HSPA9
heat shock 70kDa protein 9 (mortalin)
chr14_+_51706886 0.013 ENST00000457354.2
 TMX1
thioredoxin-related transmembrane protein 1
chr8_+_61429416 0.012 ENST00000262646.7
ENST00000531289.1
 RAB2A

RAB2A, member RAS oncogene family

chr11_+_69455855 0.012 ENST00000227507.2
ENST00000536559.1
 CCND1

cyclin D1

chr6_-_31763408 0.011 ENST00000444930.2
 VARS
valyl-tRNA synthetase
chr2_+_172290707 0.011 ENST00000375255.3
ENST00000539783.1
 DCAF17

DDB1 and CUL4 associated factor 17

chr9_-_37576226 0.009 ENST00000432825.2
 FBXO10
F-box protein 10
chrX_+_129535937 0.009 ENST00000305536.6
ENST00000370947.1
 RBMX2

RNA binding motif protein, X-linked 2

chr10_-_73611046 0.007 ENST00000394934.1
ENST00000394936.3
 PSAP

prosaposin

chr1_-_228296956 0.007 ENST00000366744.1
ENST00000348259.5
ENST00000366747.3
ENST00000366746.3
ENST00000295008.4
ENST00000336520.3
ENST00000366731.5
ENST00000411464.2
ENST00000457264.1
ENST00000336300.5
ENST00000430433.1
ENST00000391867.3
 MRPL55











mitochondrial ribosomal protein L55











chr1_+_25664408 0.006 ENST00000374358.4
 TMEM50A
transmembrane protein 50A
chr9_-_37576333 0.006 ENST00000541607.1
 FBXO10
F-box protein 10
chr1_-_100715372 0.006 ENST00000370131.3
ENST00000370132.4
 DBT

dihydrolipoamide branched chain transacylase E2

chr7_-_74489609 0.005 ENST00000329959.4
ENST00000503250.2
ENST00000543840.1
 WBSCR16


Williams-Beuren syndrome chromosome region 16


chr22_-_30162924 0.004 ENST00000344318.3
ENST00000397781.3
 ZMAT5

zinc finger, matrin-type 5

chr22_+_30163340 0.003 ENST00000330029.6
ENST00000401406.3
 UQCR10

ubiquinol-cytochrome c reductase, complex III subunit X

chr17_+_7517264 0.003 ENST00000572182.1
ENST00000574539.1
ENST00000576728.1
ENST00000575314.1
ENST00000570547.1
ENST00000572262.1
ENST00000576478.1
ENST00000593717.1
 SHBG






AC007421.1
sex hormone-binding globulin






AC007421.1
chr12_-_74686314 0.003 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
 RP11-81H3.2


RP11-81H3.2


chr16_+_68573116 0.002 ENST00000570495.1
ENST00000563169.2
ENST00000564323.1
ENST00000562156.1
ENST00000573685.1
 ZFP90




ZFP90 zinc finger protein




chr3_-_9994021 0.001 ENST00000411976.2
ENST00000412055.1
 PRRT3

proline-rich transmembrane protein 3

chr11_+_46638805 0.000 ENST00000434074.1
ENST00000312040.4
ENST00000451945.1
 ATG13


autophagy related 13



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.2 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.0 GO:0090425 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0061689 tricellular tight junction(GO:0061689)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation