Motif ID: ZNF740_ZNF219

Z-value: 0.893

Transcription factors associated with ZNF740_ZNF219:

Gene SymbolEntrez IDGene Name
ZNF219 ENSG00000165804.11 ZNF219
ZNF740 ENSG00000139651.9 ZNF740

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZNF219hg19_v2_chr14_-_21566731_21566836-0.844.5e-03Click!
ZNF740hg19_v2_chr12_+_53574464_535745390.791.2e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF740_ZNF219

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_96184913 2.154 ENST00000538383.1
NTN4
netrin 4
chr17_+_72427477 1.849 ENST00000342648.5
ENST00000481232.1
GPRC5C

G protein-coupled receptor, family C, group 5, member C

chr12_-_96184533 1.782 ENST00000343702.4
ENST00000344911.4
NTN4

netrin 4

chr14_-_54418598 1.781 ENST00000609748.1
ENST00000558961.1
BMP4

bone morphogenetic protein 4

chr2_-_145277882 1.533 ENST00000465070.1
ENST00000444559.1
ZEB2

zinc finger E-box binding homeobox 2

chr9_+_118916082 1.240 ENST00000328252.3
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr3_+_184032919 1.105 ENST00000427845.1
ENST00000342981.4
ENST00000319274.6
EIF4G1


eukaryotic translation initiation factor 4 gamma, 1


chr11_+_134201768 1.091 ENST00000535456.2
ENST00000339772.7
GLB1L2

galactosidase, beta 1-like 2

chr1_+_164528866 1.061 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr5_-_87969130 1.030 ENST00000505030.1
ENST00000500197.2
LINC00461

long intergenic non-protein coding RNA 461

chr8_+_75896731 0.941 ENST00000262207.4
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr11_+_134201911 0.931 ENST00000389881.3
GLB1L2
galactosidase, beta 1-like 2
chr5_+_133861339 0.887 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15


jade family PHD finger 2


chr7_+_94537542 0.861 ENST00000433881.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chr3_-_171178157 0.848 ENST00000465393.1
ENST00000436636.2
ENST00000369326.5
ENST00000538048.1
ENST00000341852.6
TNIK




TRAF2 and NCK interacting kinase




chr8_+_75896849 0.826 ENST00000520277.1
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr17_-_6459802 0.776 ENST00000262483.8
PITPNM3
PITPNM family member 3
chr19_+_54412517 0.767 ENST00000391767.1
CACNG7
calcium channel, voltage-dependent, gamma subunit 7
chrX_-_74145273 0.763 ENST00000055682.6
KIAA2022
KIAA2022
chr3_-_171177852 0.755 ENST00000284483.8
ENST00000475336.1
ENST00000357327.5
ENST00000460047.1
ENST00000488470.1
ENST00000470834.1
TNIK





TRAF2 and NCK interacting kinase





chr6_+_31865552 0.750 ENST00000469372.1
ENST00000497706.1
C2

complement component 2

chr3_+_184033135 0.689 ENST00000424196.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr1_-_177133818 0.668 ENST00000424564.2
ENST00000361833.2
ASTN1

astrotactin 1

chr1_-_111746966 0.667 ENST00000369752.5
DENND2D
DENN/MADD domain containing 2D
chr9_-_140115775 0.663 ENST00000391553.1
ENST00000392827.1
RNF208

ring finger protein 208

chr6_-_32157947 0.627 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr3_+_184032283 0.614 ENST00000346169.2
ENST00000414031.1
EIF4G1

eukaryotic translation initiation factor 4 gamma, 1

chr18_+_3449821 0.611 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1


TGFB-induced factor homeobox 1


chr6_-_33285505 0.601 ENST00000431845.2
ZBTB22
zinc finger and BTB domain containing 22
chr2_+_154728426 0.600 ENST00000392825.3
ENST00000434213.1
GALNT13

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)

chr8_+_120428546 0.590 ENST00000259526.3
NOV
nephroblastoma overexpressed
chr17_-_27277615 0.575 ENST00000583747.1
ENST00000584236.1
PHF12

PHD finger protein 12

chr12_-_53614155 0.568 ENST00000543726.1
RARG
retinoic acid receptor, gamma
chr20_-_22565101 0.568 ENST00000419308.2
FOXA2
forkhead box A2
chr12_+_57522692 0.560 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1
chrX_-_43741594 0.557 ENST00000536181.1
ENST00000378069.4
MAOB

monoamine oxidase B

chr7_+_94537247 0.551 ENST00000422324.1
PPP1R9A
protein phosphatase 1, regulatory subunit 9A
chrX_+_105066524 0.547 ENST00000243300.9
ENST00000428173.2
NRK

Nik related kinase

chr1_+_170633047 0.521 ENST00000239461.6
ENST00000497230.2
PRRX1

paired related homeobox 1

chr12_+_57522439 0.520 ENST00000338962.4
LRP1
low density lipoprotein receptor-related protein 1
chr18_+_3449695 0.517 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chr7_+_73245193 0.505 ENST00000340958.2
CLDN4
claudin 4
chr3_+_184032313 0.503 ENST00000392537.2
ENST00000444134.1
ENST00000450424.1
ENST00000421110.1
ENST00000382330.3
ENST00000426123.1
ENST00000350481.5
ENST00000455679.1
ENST00000440448.1
EIF4G1








eukaryotic translation initiation factor 4 gamma, 1








chr10_-_104001231 0.497 ENST00000370002.3
PITX3
paired-like homeodomain 3
chr2_-_145277569 0.497 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr5_-_124084493 0.484 ENST00000509799.1
ZNF608
zinc finger protein 608
chr9_-_86153218 0.466 ENST00000304195.3
ENST00000376438.1
FRMD3

FERM domain containing 3

chr12_+_57522258 0.462 ENST00000553277.1
ENST00000243077.3
LRP1

low density lipoprotein receptor-related protein 1

chr2_-_148779106 0.458 ENST00000416719.1
ENST00000264169.2
ORC4

origin recognition complex, subunit 4

chr8_-_11058847 0.456 ENST00000297303.4
ENST00000416569.2
XKR6

XK, Kell blood group complex subunit-related family, member 6

chr3_+_184032419 0.452 ENST00000352767.3
ENST00000427141.2
EIF4G1

eukaryotic translation initiation factor 4 gamma, 1

chr12_-_53614043 0.447 ENST00000338561.5
RARG
retinoic acid receptor, gamma
chr2_-_148778323 0.441 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4



origin recognition complex, subunit 4



chr1_-_6321035 0.428 ENST00000377893.2
GPR153
G protein-coupled receptor 153
chr1_+_164528437 0.421 ENST00000485769.1
PBX1
pre-B-cell leukemia homeobox 1
chr5_-_146833485 0.421 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr17_+_46131912 0.415 ENST00000584634.1
ENST00000580050.1
NFE2L1

nuclear factor, erythroid 2-like 1

chr5_+_32711419 0.408 ENST00000265074.8
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr14_-_105635090 0.407 ENST00000331782.3
ENST00000347004.2
JAG2

jagged 2

chr18_+_3450161 0.407 ENST00000551402.1
ENST00000577543.1
TGIF1

TGFB-induced factor homeobox 1

chr1_+_6845578 0.400 ENST00000467404.2
ENST00000439411.2
CAMTA1

calmodulin binding transcription activator 1

chrX_+_105066554 0.400 ENST00000536164.1
NRK
Nik related kinase
chr1_+_6673745 0.399 ENST00000377648.4
PHF13
PHD finger protein 13
chr17_-_27278304 0.397 ENST00000577226.1
PHF12
PHD finger protein 12
chr17_+_46132037 0.396 ENST00000582155.1
ENST00000583378.1
ENST00000536222.1
NFE2L1


nuclear factor, erythroid 2-like 1


chr12_+_53817633 0.389 ENST00000257863.4
ENST00000550311.1
ENST00000379791.3
AMHR2


anti-Mullerian hormone receptor, type II


chr10_+_12391685 0.387 ENST00000378845.1
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr8_-_26371608 0.386 ENST00000522362.2
PNMA2
paraneoplastic Ma antigen 2
chr4_-_168155730 0.384 ENST00000502330.1
ENST00000357154.3
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr1_-_98511756 0.369 ENST00000602984.1
ENST00000602852.1
MIR137HG

MIR137 host gene (non-protein coding)

chr3_+_184033551 0.368 ENST00000456033.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr15_+_92396920 0.364 ENST00000318445.6
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr1_-_177133998 0.354 ENST00000367657.3
ASTN1
astrotactin 1
chr2_-_55277654 0.354 ENST00000337526.6
ENST00000317610.7
ENST00000357732.4
RTN4


reticulon 4


chr6_+_45390222 0.352 ENST00000359524.5
RUNX2
runt-related transcription factor 2
chr17_+_46131843 0.349 ENST00000577411.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr4_-_168155577 0.347 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3





sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3





chr1_-_27930102 0.344 ENST00000247087.5
ENST00000374011.2
AHDC1

AT hook, DNA binding motif, containing 1

chr7_-_73184588 0.340 ENST00000395145.2
CLDN3
claudin 3
chr6_-_34664612 0.338 ENST00000374023.3
ENST00000374026.3
C6orf106

chromosome 6 open reading frame 106

chr2_-_55277436 0.338 ENST00000354474.6
RTN4
reticulon 4
chr14_-_23451845 0.336 ENST00000262713.2
AJUBA
ajuba LIM protein
chr5_+_32711829 0.334 ENST00000415167.2
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr1_-_177134024 0.327 ENST00000367654.3
ASTN1
astrotactin 1
chr4_-_168155700 0.325 ENST00000357545.4
ENST00000512648.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr5_-_146833222 0.325 ENST00000534907.1
DPYSL3
dihydropyrimidinase-like 3
chr15_+_92397051 0.321 ENST00000424469.2
SLCO3A1
solute carrier organic anion transporter family, member 3A1
chr7_-_100493482 0.315 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
ACHE



acetylcholinesterase (Yt blood group)



chr16_+_14396121 0.314 ENST00000570945.1
RP11-65J21.3
RP11-65J21.3
chr2_+_204193149 0.313 ENST00000422511.2
ABI2
abl-interactor 2
chr19_-_49015050 0.312 ENST00000600059.1
LMTK3
lemur tyrosine kinase 3
chr2_+_24272576 0.307 ENST00000380986.4
ENST00000452109.1
FKBP1B

FK506 binding protein 1B, 12.6 kDa

chr6_-_41908428 0.300 ENST00000505064.1
CCND3
cyclin D3
chr2_+_207308220 0.296 ENST00000264377.3
ADAM23
ADAM metallopeptidase domain 23
chr9_+_35792151 0.287 ENST00000342694.2
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr5_-_87980753 0.286 ENST00000511014.2
LINC00461
long intergenic non-protein coding RNA 461
chr14_-_23451467 0.285 ENST00000361265.4
ENST00000555074.1
AJUBA
RP11-298I3.5
ajuba LIM protein
RP11-298I3.5
chr2_-_197458271 0.278 ENST00000427457.1
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr14_+_23352374 0.276 ENST00000267396.4
ENST00000536884.1
REM2

RAS (RAD and GEM)-like GTP binding 2

chr8_+_26149274 0.276 ENST00000522535.1
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr2_+_181845532 0.270 ENST00000602475.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr6_+_43739697 0.269 ENST00000230480.6
VEGFA
vascular endothelial growth factor A
chr14_-_81687197 0.268 ENST00000553612.1
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr2_+_24272543 0.266 ENST00000380991.4
FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr4_-_168155417 0.266 ENST00000511269.1
ENST00000506697.1
ENST00000512042.1
SPOCK3


sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3


chr2_-_197458323 0.263 ENST00000452031.1
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr17_-_6459768 0.259 ENST00000421306.3
PITPNM3
PITPNM family member 3
chr2_+_149402553 0.259 ENST00000258484.6
ENST00000409654.1
EPC2

enhancer of polycomb homolog 2 (Drosophila)

chr7_+_117120017 0.253 ENST00000003084.6
ENST00000454343.1
CFTR

cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)

chr5_-_142784101 0.248 ENST00000503201.1
ENST00000502892.1
NR3C1

nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

chr17_-_65992544 0.245 ENST00000580729.1
RP11-855A2.5
RP11-855A2.5
chr2_-_174828892 0.245 ENST00000418194.2
SP3
Sp3 transcription factor
chr1_+_164529004 0.244 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
PBX1



pre-B-cell leukemia homeobox 1



chr2_-_224702270 0.243 ENST00000396654.2
ENST00000396653.2
ENST00000423110.1
ENST00000443700.1
AP1S3



adaptor-related protein complex 1, sigma 3 subunit



chr1_-_167906277 0.243 ENST00000271373.4
MPC2
mitochondrial pyruvate carrier 2
chr2_-_224702201 0.241 ENST00000446015.2
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr12_-_57522813 0.237 ENST00000556155.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr2_-_55277692 0.236 ENST00000394611.2
RTN4
reticulon 4
chr12_-_26278030 0.235 ENST00000242728.4
BHLHE41
basic helix-loop-helix family, member e41
chr1_+_169075554 0.232 ENST00000367815.4
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr1_+_6845384 0.232 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr2_+_33172012 0.232 ENST00000404816.2
LTBP1
latent transforming growth factor beta binding protein 1
chr17_-_27278445 0.231 ENST00000268756.3
ENST00000584685.1
PHF12

PHD finger protein 12

chr20_+_19738300 0.229 ENST00000432334.1
RP1-122P22.2
RP1-122P22.2
chr17_-_42277203 0.229 ENST00000587097.1
ATXN7L3
ataxin 7-like 3
chr6_-_41909191 0.229 ENST00000512426.1
ENST00000372987.4
CCND3

cyclin D3

chr2_+_181845763 0.227 ENST00000602499.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr2_+_149402989 0.223 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr17_+_36861735 0.219 ENST00000378137.5
ENST00000325718.7
MLLT6

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6

chr7_-_79082867 0.216 ENST00000419488.1
ENST00000354212.4
MAGI2

membrane associated guanylate kinase, WW and PDZ domain containing 2

chr2_-_224702740 0.215 ENST00000444408.1
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr17_-_36904437 0.209 ENST00000585100.1
ENST00000360797.2
ENST00000578109.1
ENST00000579882.1
PCGF2



polycomb group ring finger 2



chr11_+_62475130 0.207 ENST00000294117.5
GNG3
guanine nucleotide binding protein (G protein), gamma 3
chr8_+_17104401 0.207 ENST00000324815.3
ENST00000518038.1
VPS37A

vacuolar protein sorting 37 homolog A (S. cerevisiae)

chr6_+_44095347 0.206 ENST00000323267.6
TMEM63B
transmembrane protein 63B
chr2_-_55277512 0.206 ENST00000402434.2
RTN4
reticulon 4
chr3_-_24536453 0.202 ENST00000453729.2
ENST00000413780.1
THRB

thyroid hormone receptor, beta

chr1_+_33352036 0.201 ENST00000373467.3
HPCA
hippocalcin
chrX_+_67913471 0.201 ENST00000374597.3
STARD8
StAR-related lipid transfer (START) domain containing 8
chr17_+_34136459 0.199 ENST00000588240.1
ENST00000590273.1
ENST00000588441.1
ENST00000587272.1
ENST00000592237.1
ENST00000311979.3
TAF15





TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa





chr6_+_20403997 0.198 ENST00000535432.1
E2F3
E2F transcription factor 3
chr3_-_88108212 0.198 ENST00000482016.1
CGGBP1
CGG triplet repeat binding protein 1
chr22_+_46546494 0.198 ENST00000396000.2
ENST00000262735.5
ENST00000420804.1
PPARA


peroxisome proliferator-activated receptor alpha


chr6_-_31697563 0.197 ENST00000375789.2
ENST00000416410.1
DDAH2

dimethylarginine dimethylaminohydrolase 2

chr1_+_6845497 0.197 ENST00000473578.1
ENST00000557126.1
CAMTA1

calmodulin binding transcription activator 1

chr19_+_7660716 0.196 ENST00000160298.4
ENST00000446248.2
CAMSAP3

calmodulin regulated spectrin-associated protein family, member 3

chr11_-_46142948 0.195 ENST00000257821.4
PHF21A
PHD finger protein 21A
chr5_+_133861790 0.194 ENST00000395003.1
PHF15
jade family PHD finger 2
chr13_-_45010939 0.194 ENST00000261489.2
TSC22D1
TSC22 domain family, member 1
chr5_-_124082279 0.193 ENST00000513986.1
ZNF608
zinc finger protein 608
chr10_+_52751010 0.192 ENST00000373985.1
PRKG1
protein kinase, cGMP-dependent, type I
chr6_-_31697255 0.192 ENST00000436437.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr3_+_181429704 0.192 ENST00000431565.2
ENST00000325404.1
SOX2

SRY (sex determining region Y)-box 2

chrX_+_49126294 0.190 ENST00000466508.1
ENST00000438316.1
ENST00000055335.6
ENST00000495799.1
PPP1R3F



protein phosphatase 1, regulatory subunit 3F



chr19_-_40324255 0.189 ENST00000593685.1
ENST00000600611.1
DYRK1B

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B

chr2_+_204192942 0.188 ENST00000295851.5
ENST00000261017.5
ABI2

abl-interactor 2

chr1_-_211752073 0.184 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr9_+_92219919 0.183 ENST00000252506.6
ENST00000375769.1
GADD45G

growth arrest and DNA-damage-inducible, gamma

chr2_-_56150910 0.182 ENST00000424836.2
ENST00000438672.1
ENST00000440439.1
ENST00000429909.1
ENST00000424207.1
ENST00000452337.1
ENST00000355426.3
ENST00000439193.1
ENST00000421664.1
EFEMP1








EGF containing fibulin-like extracellular matrix protein 1








chr2_-_219925189 0.182 ENST00000295731.6
IHH
indian hedgehog
chr6_+_31515337 0.179 ENST00000376148.4
ENST00000376145.4
NFKBIL1

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1

chr12_+_57482877 0.179 ENST00000342556.6
ENST00000357680.4
NAB2

NGFI-A binding protein 2 (EGR1 binding protein 2)

chr2_+_33172221 0.176 ENST00000354476.3
LTBP1
latent transforming growth factor beta binding protein 1
chr1_+_154975110 0.175 ENST00000535420.1
ENST00000368426.3
ZBTB7B

zinc finger and BTB domain containing 7B

chr8_-_494824 0.175 ENST00000427263.2
ENST00000324079.6
TDRP

testis development related protein

chr14_-_81687575 0.175 ENST00000434192.2
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chrX_+_48367338 0.172 ENST00000359882.4
ENST00000537758.1
ENST00000367574.4
ENST00000355961.4
ENST00000489940.1
ENST00000361988.3
PORCN





porcupine homolog (Drosophila)





chr6_-_31869769 0.169 ENST00000375527.2
ZBTB12
zinc finger and BTB domain containing 12
chrX_+_51636629 0.169 ENST00000375722.1
ENST00000326587.7
ENST00000375695.2
MAGED1


melanoma antigen family D, 1


chr11_+_130184888 0.168 ENST00000602376.1
ENST00000532116.3
ENST00000602310.1
RP11-121M22.1


RP11-121M22.1


chr5_+_137688285 0.168 ENST00000314358.5
KDM3B
lysine (K)-specific demethylase 3B
chr12_+_56401268 0.168 ENST00000262032.5
IKZF4
IKAROS family zinc finger 4 (Eos)
chr12_-_6798025 0.167 ENST00000542351.1
ENST00000538829.1
ZNF384

zinc finger protein 384

chr2_-_161349909 0.167 ENST00000392753.3
RBMS1
RNA binding motif, single stranded interacting protein 1
chr2_-_148778258 0.167 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
ORC4



origin recognition complex, subunit 4



chr2_+_181845843 0.166 ENST00000602710.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr2_+_111878483 0.164 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
BCL2L11




BCL2-like 11 (apoptosis facilitator)




chr3_+_179280668 0.163 ENST00000429709.2
ENST00000450518.2
ENST00000392662.1
ENST00000490364.1
ACTL6A



actin-like 6A



chr17_+_43238438 0.163 ENST00000593138.1
ENST00000586681.1
HEXIM2

hexamethylene bis-acetamide inducible 2

chr15_-_93199069 0.163 ENST00000327355.5
FAM174B
family with sequence similarity 174, member B
chr20_+_58179582 0.163 ENST00000371015.1
ENST00000395639.4
PHACTR3

phosphatase and actin regulator 3

chr2_-_230786378 0.161 ENST00000430954.1
TRIP12
thyroid hormone receptor interactor 12
chr7_-_100493744 0.161 ENST00000428317.1
ENST00000441605.1
ACHE

acetylcholinesterase (Yt blood group)

chr6_-_112575687 0.161 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
LAMA4


laminin, alpha 4


chr8_+_17104539 0.161 ENST00000521829.1
ENST00000521005.1
VPS37A

vacuolar protein sorting 37 homolog A (S. cerevisiae)

chr7_+_7222157 0.158 ENST00000419721.1
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr1_+_164528616 0.157 ENST00000340699.3
PBX1
pre-B-cell leukemia homeobox 1
chr9_-_14313893 0.156 ENST00000380921.3
ENST00000380959.3
NFIB

nuclear factor I/B

chr7_+_73442457 0.156 ENST00000438880.1
ENST00000414324.1
ENST00000380562.4
ELN


elastin


chr2_+_204193129 0.154 ENST00000417864.1
ABI2
abl-interactor 2
chr17_+_38497640 0.153 ENST00000394086.3
RARA
retinoic acid receptor, alpha
chr11_-_46142615 0.153 ENST00000529734.1
ENST00000323180.6
PHF21A

PHD finger protein 21A

chr12_+_53818855 0.151 ENST00000550839.1
AMHR2
anti-Mullerian hormone receptor, type II
chr6_+_42749759 0.150 ENST00000314073.5
GLTSCR1L
GLTSCR1-like
chr11_+_77532233 0.150 ENST00000525409.1
AAMDC
adipogenesis associated, Mth938 domain containing
chr1_-_33430286 0.149 ENST00000373456.7
ENST00000356990.5
ENST00000235150.4
RNF19B


ring finger protein 19B


chr8_+_26149007 0.149 ENST00000380737.3
ENST00000524169.1
PPP2R2A

protein phosphatase 2, regulatory subunit B, alpha

chr6_-_112575912 0.148 ENST00000522006.1
ENST00000230538.7
ENST00000519932.1
LAMA4


laminin, alpha 4


chr6_-_24721054 0.148 ENST00000378119.4
C6orf62
chromosome 6 open reading frame 62
chr6_+_36853607 0.148 ENST00000480824.2
ENST00000355190.3
ENST00000373685.1
C6orf89


chromosome 6 open reading frame 89



Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.9 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.4 1.8 GO:1905072 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.4 1.4 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.3 1.5 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.2 3.7 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.2 2.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 2.0 GO:1902748 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.2 1.0 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.2 0.5 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.6 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.6 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 1.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.3 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.1 0.5 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.1 0.4 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.1 0.6 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.1 0.3 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.5 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.3 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.1 0.3 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 0.3 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.1 1.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.6 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.6 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.2 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 0.2 GO:0061760 antifungal innate immune response(GO:0061760)
0.1 0.2 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.1 1.9 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 0.2 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.2 GO:0098972 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.1 0.2 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.1 0.3 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.0 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.7 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.7 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.2 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.4 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.5 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 1.4 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.0 0.3 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.4 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.1 GO:0051466 positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 0.2 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.6 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.2 GO:0003402 planar cell polarity pathway involved in axis elongation(GO:0003402)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.2 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.7 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.1 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.0 1.6 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0042660 positive regulation of cell fate specification(GO:0042660)
0.0 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.2 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.0 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.3 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.2 GO:1902075 cellular response to salt(GO:1902075)
0.0 0.2 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0060214 endocardium formation(GO:0060214)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 1.2 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.4 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.9 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.1 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.0 0.2 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.1 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.1 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.0 0.2 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.1 GO:0001172 transcription, RNA-templated(GO:0001172)
0.0 0.2 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.4 GO:0070262 mitotic nuclear envelope reassembly(GO:0007084) peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.8 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.1 GO:2001076 thorax and anterior abdomen determination(GO:0007356) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.2 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.4 GO:0000052 citrulline metabolic process(GO:0000052)
0.0 0.3 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 1.1 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0060318 regulation of definitive erythrocyte differentiation(GO:0010724) definitive erythrocyte differentiation(GO:0060318)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:2000172 regulation of branching morphogenesis of a nerve(GO:2000172)
0.0 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.1 GO:0042659 regulation of cell fate specification(GO:0042659)
0.0 0.1 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.0 0.1 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.1 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.2 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.0 0.7 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.2 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.2 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.0 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.2 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.1 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 1.0 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.2 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.1 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.0 0.1 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.1 GO:2001028 positive regulation of endothelial cell chemotaxis(GO:2001028)
0.0 0.1 GO:0031577 spindle checkpoint(GO:0031577)
0.0 0.4 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.1 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.0 GO:0061181 regulation of chondrocyte development(GO:0061181)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 GO:0044326 dendritic spine neck(GO:0044326)
0.1 3.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.8 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 1.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.4 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.2 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.1 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0043291 RAVE complex(GO:0043291)
0.0 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.0 0.4 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 1.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 5.0 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0075341 host cell PML body(GO:0075341)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.7 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.0 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.0 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 1.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.4 3.9 GO:0043237 laminin-1 binding(GO:0043237)
0.2 3.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 2.0 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.5 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 1.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 1.8 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.5 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.6 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 0.4 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.1 2.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.6 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.3 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.1 1.0 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.4 GO:0050436 microfibril binding(GO:0050436)
0.1 0.6 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.2 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.1 0.4 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 1.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 1.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 1.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 3.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 1.4 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 1.0 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.7 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0003968 RNA-directed RNA polymerase activity(GO:0003968)
0.0 0.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.4 GO:0048156 tau protein binding(GO:0048156)
0.0 0.6 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0 0.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.0 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.0 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 PID_ALK2_PATHWAY ALK2 signaling events
0.1 4.4 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 1.4 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 4.0 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.1 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.3 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 2.5 PID_TNF_PATHWAY TNF receptor signaling pathway
0.0 1.6 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 1.5 PID_BMP_PATHWAY BMP receptor signaling
0.0 0.5 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 1.3 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 1.6 PID_REG_GR_PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 0.1 ST_STAT3_PATHWAY STAT3 Pathway
0.0 0.4 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 3.3 NABA_ECM_GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.9 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.3 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.7 REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT Genes involved in Initial triggering of complement
0.0 3.0 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.7 REACTOME_TRANSPORT_OF_ORGANIC_ANIONS Genes involved in Transport of organic anions
0.0 1.3 REACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.3 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.7 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME_SIGNALING_BY_NOTCH2 Genes involved in Signaling by NOTCH2
0.0 0.8 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.0 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.7 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.1 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.1 REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME_ROLE_OF_DCC_IN_REGULATING_APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins