Motif ID: ZNF423

Z-value: 0.386


Transcription factors associated with ZNF423:

Gene SymbolEntrez IDGene Name
ZNF423 ENSG00000102935.7 ZNF423



Activity profile for motif ZNF423.

activity profile for motif ZNF423


Sorted Z-values histogram for motif ZNF423

Sorted Z-values for motif ZNF423



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF423

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_150400124 0.950 ENST00000388825.4
ENST00000521650.1
ENST00000517973.1
 GPX3


glutathione peroxidase 3 (plasma)


chr12_+_52643077 0.652 ENST00000553310.2
ENST00000544024.1
 KRT86

keratin 86

chr2_+_14772810 0.623 ENST00000295092.2
ENST00000331243.4
 FAM84A

family with sequence similarity 84, member A

chr9_+_135037334 0.443 ENST00000393229.3
ENST00000360670.3
ENST00000393228.4
ENST00000372179.3
 NTNG2



netrin G2



chr2_+_12246664 0.421 ENST00000449986.1
 AC096559.1
AC096559.1
chr13_+_96743093 0.357 ENST00000376705.2
 HS6ST3
heparan sulfate 6-O-sulfotransferase 3
chrX_+_106163626 0.248 ENST00000336803.1
 CLDN2
claudin 2
chr9_-_130742792 0.232 ENST00000373095.1
 FAM102A
family with sequence similarity 102, member A
chr20_-_25062767 0.207 ENST00000429762.3
ENST00000444511.2
ENST00000376707.3
 VSX1


visual system homeobox 1


chr22_-_37823468 0.197 ENST00000402918.2
 ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr4_-_152329987 0.195 ENST00000508847.1
 RP11-610P16.1
RP11-610P16.1
chr9_-_39239171 0.188 ENST00000358144.2
 CNTNAP3
contactin associated protein-like 3
chr22_-_38484922 0.186 ENST00000428572.1
 BAIAP2L2
BAI1-associated protein 2-like 2
chrX_-_48827976 0.184 ENST00000218176.3
 KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr8_+_22022653 0.170 ENST00000354870.5
ENST00000397816.3
ENST00000306349.8
 BMP1


bone morphogenetic protein 1


chr1_+_26644441 0.170 ENST00000374213.2
 CD52
CD52 molecule
chr8_+_22022800 0.160 ENST00000397814.3
 BMP1
bone morphogenetic protein 1
chr3_+_180630444 0.151 ENST00000491062.1
ENST00000468861.1
ENST00000445140.2
ENST00000484958.1
 FXR1



fragile X mental retardation, autosomal homolog 1



chr8_+_22022223 0.150 ENST00000306385.5
 BMP1
bone morphogenetic protein 1
chr1_+_10459111 0.141 ENST00000541529.1
ENST00000270776.8
ENST00000483936.1
ENST00000538557.1
 PGD



phosphogluconate dehydrogenase



chr5_-_172756506 0.132 ENST00000265087.4
 STC2
stanniocalcin 2
chr19_-_5292781 0.132 ENST00000586065.1
 PTPRS
protein tyrosine phosphatase, receptor type, S
chr6_-_33663474 0.131 ENST00000594414.1
 SBP1
SBP1; Uncharacterized protein
chr11_-_44972390 0.130 ENST00000395648.3
ENST00000531928.2
 TP53I11

tumor protein p53 inducible protein 11

chr3_+_180630090 0.129 ENST00000357559.4
ENST00000305586.7
 FXR1

fragile X mental retardation, autosomal homolog 1

chr4_+_152330409 0.123 ENST00000513086.1
 FAM160A1
family with sequence similarity 160, member A1
chr5_+_68788594 0.119 ENST00000396442.2
ENST00000380766.2
 OCLN

occludin

chr4_+_152330390 0.113 ENST00000503146.1
ENST00000435205.1
 FAM160A1

family with sequence similarity 160, member A1

chr12_+_57522692 0.113 ENST00000554174.1
 LRP1
low density lipoprotein receptor-related protein 1
chr7_-_100491854 0.111 ENST00000426415.1
ENST00000430554.1
ENST00000412389.1
 ACHE


acetylcholinesterase (Yt blood group)


chr3_-_196439065 0.108 ENST00000399942.4
ENST00000409690.3
 CEP19

centrosomal protein 19kDa

chr10_+_135340859 0.108 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
 CYP2E1


cytochrome P450, family 2, subfamily E, polypeptide 1


chr4_+_71570430 0.105 ENST00000417478.2
 RUFY3
RUN and FYVE domain containing 3
chr6_+_33589161 0.103 ENST00000605930.1
 ITPR3
inositol 1,4,5-trisphosphate receptor, type 3
chrX_+_49028265 0.099 ENST00000376322.3
ENST00000376327.5
 PLP2

proteolipid protein 2 (colonic epithelium-enriched)

chr2_+_135011731 0.098 ENST00000281923.2
 MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr11_-_64510409 0.097 ENST00000394429.1
ENST00000394428.1
 RASGRP2

RAS guanyl releasing protein 2 (calcium and DAG-regulated)

chr12_+_57522439 0.095 ENST00000338962.4
 LRP1
low density lipoprotein receptor-related protein 1
chr2_-_120980939 0.094 ENST00000426077.2
 TMEM185B
transmembrane protein 185B
chr11_-_61062762 0.090 ENST00000335613.5
 VWCE
von Willebrand factor C and EGF domains
chr9_-_99381660 0.083 ENST00000375240.3
ENST00000463569.1
 CDC14B

cell division cycle 14B

chr8_+_30241995 0.081 ENST00000397323.4
ENST00000339877.4
ENST00000320203.4
ENST00000287771.5
 RBPMS



RNA binding protein with multiple splicing



chr4_-_20985632 0.081 ENST00000359001.5
 KCNIP4
Kv channel interacting protein 4
chr7_-_44265492 0.072 ENST00000425809.1
 CAMK2B
calcium/calmodulin-dependent protein kinase II beta
chr3_+_180630319 0.071 ENST00000491674.1
 FXR1
fragile X mental retardation, autosomal homolog 1
chr2_-_206950781 0.069 ENST00000403263.1
 INO80D
INO80 complex subunit D
chr9_-_99382065 0.068 ENST00000265659.2
ENST00000375241.1
ENST00000375236.1
 CDC14B


cell division cycle 14B


chr11_-_44972418 0.066 ENST00000525680.1
ENST00000528290.1
ENST00000530035.1
 TP53I11


tumor protein p53 inducible protein 11


chr1_+_24118452 0.065 ENST00000421070.1
 LYPLA2
lysophospholipase II
chr17_+_28705921 0.062 ENST00000225719.4
 CPD
carboxypeptidase D
chr8_+_30241934 0.061 ENST00000538486.1
 RBPMS
RNA binding protein with multiple splicing
chr9_-_131486367 0.059 ENST00000372663.4
ENST00000406904.2
ENST00000452105.1
ENST00000372672.2
ENST00000372667.5
 ZDHHC12




zinc finger, DHHC-type containing 12




chr9_-_35619539 0.059 ENST00000396757.1
 CD72
CD72 molecule
chr2_+_46770531 0.058 ENST00000482449.2
 RHOQ
ras homolog family member Q
chr11_-_44972299 0.055 ENST00000528473.1
 TP53I11
tumor protein p53 inducible protein 11
chr1_+_55271736 0.054 ENST00000358193.3
ENST00000371273.3
 C1orf177

chromosome 1 open reading frame 177

chrX_-_1572629 0.051 ENST00000534940.1
 ASMTL
acetylserotonin O-methyltransferase-like
chr7_-_23053719 0.049 ENST00000432176.2
ENST00000440481.1
 FAM126A

family with sequence similarity 126, member A

chr9_-_124976185 0.048 ENST00000464484.2
 LHX6
LIM homeobox 6
chr15_+_41523417 0.046 ENST00000560397.1
 CHP1
calcineurin-like EF-hand protein 1
chr15_+_41523335 0.045 ENST00000334660.5
 CHP1
calcineurin-like EF-hand protein 1
chr17_+_36584662 0.044 ENST00000431231.2
ENST00000437668.3
 ARHGAP23

Rho GTPase activating protein 23

chr11_-_6495082 0.043 ENST00000536344.1
 TRIM3
tripartite motif containing 3
chr16_-_85146040 0.043 ENST00000539556.1
 FAM92B
family with sequence similarity 92, member B
chr12_-_57522813 0.041 ENST00000556155.1
 STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr5_+_141303461 0.041 ENST00000508751.1
 KIAA0141
KIAA0141
chr5_+_154181816 0.040 ENST00000518677.1
 LARP1
La ribonucleoprotein domain family, member 1
chr3_+_196439170 0.039 ENST00000392391.3
ENST00000314118.4
 PIGX

phosphatidylinositol glycan anchor biosynthesis, class X

chr7_-_23053693 0.038 ENST00000409763.1
ENST00000409923.1
 FAM126A

family with sequence similarity 126, member A

chr4_-_166034004 0.038 ENST00000505095.1
 TMEM192
transmembrane protein 192
chr11_-_6495101 0.038 ENST00000528227.1
ENST00000359518.3
ENST00000345851.3
ENST00000537602.1
 TRIM3



tripartite motif containing 3



chr2_-_206950996 0.037 ENST00000414320.1
 INO80D
INO80 complex subunit D
chr18_-_60985914 0.036 ENST00000589955.1
 BCL2
B-cell CLL/lymphoma 2
chr11_-_44971702 0.036 ENST00000533940.1
ENST00000533937.1
 TP53I11

tumor protein p53 inducible protein 11

chr11_-_44972476 0.033 ENST00000527685.1
ENST00000308212.5
 TP53I11

tumor protein p53 inducible protein 11

chr3_+_196439275 0.033 ENST00000296333.5
 PIGX
phosphatidylinositol glycan anchor biosynthesis, class X
chr8_-_103668114 0.030 ENST00000285407.6
 KLF10
Kruppel-like factor 10
chr9_+_130160440 0.030 ENST00000439597.1
ENST00000423934.1
 SLC2A8

solute carrier family 2 (facilitated glucose transporter), member 8

chr11_-_61659006 0.030 ENST00000278829.2
 FADS3
fatty acid desaturase 3
chr5_+_141303373 0.030 ENST00000432126.2
ENST00000194118.4
 KIAA0141

KIAA0141

chr11_-_61658853 0.030 ENST00000525588.1
ENST00000540820.1
 FADS3

fatty acid desaturase 3

chr1_-_203055129 0.029 ENST00000241651.4
 MYOG
myogenin (myogenic factor 4)
chr19_+_6740888 0.029 ENST00000596673.1
 TRIP10
thyroid hormone receptor interactor 10
chr2_+_46769798 0.028 ENST00000238738.4
 RHOQ
ras homolog family member Q
chr14_-_93582214 0.028 ENST00000556603.2
ENST00000354313.3
 ITPK1

inositol-tetrakisphosphate 1-kinase

chr17_-_1029052 0.027 ENST00000574437.1
 ABR
active BCR-related
chr16_-_11681316 0.027 ENST00000571688.1
 LITAF
lipopolysaccharide-induced TNF factor
chr20_+_43029911 0.027 ENST00000443598.2
ENST00000316099.4
ENST00000415691.2
 HNF4A


hepatocyte nuclear factor 4, alpha


chr19_+_14544099 0.026 ENST00000242783.6
ENST00000586557.1
ENST00000590097.1
 PKN1


protein kinase N1


chr2_+_171785012 0.025 ENST00000234160.4
 GORASP2
golgi reassembly stacking protein 2, 55kDa
chr17_-_27230035 0.025 ENST00000378895.4
ENST00000394901.3
 DHRS13

dehydrogenase/reductase (SDR family) member 13

chr4_-_120548779 0.024 ENST00000264805.5
 PDE5A
phosphodiesterase 5A, cGMP-specific
chrX_+_152760397 0.024 ENST00000331595.4
ENST00000431891.1
 BGN

biglycan

chr8_-_42234745 0.023 ENST00000220812.2
 DKK4
dickkopf WNT signaling pathway inhibitor 4
chr11_-_1036706 0.023 ENST00000421673.2
 MUC6
mucin 6, oligomeric mucus/gel-forming
chr4_-_166034029 0.023 ENST00000306480.6
 TMEM192
transmembrane protein 192
chr11_+_73019282 0.023 ENST00000263674.3
 ARHGEF17
Rho guanine nucleotide exchange factor (GEF) 17
chr9_+_112542572 0.022 ENST00000374530.3
 PALM2-AKAP2
PALM2-AKAP2 readthrough
chr12_+_7037461 0.022 ENST00000396684.2
 ATN1
atrophin 1
chr3_+_107244229 0.022 ENST00000456419.1
ENST00000402163.2
 BBX

bobby sox homolog (Drosophila)

chr2_+_171785824 0.020 ENST00000452526.2
 GORASP2
golgi reassembly stacking protein 2, 55kDa
chr8_+_22422749 0.019 ENST00000523900.1
 SORBS3
sorbin and SH3 domain containing 3
chr14_-_93582148 0.018 ENST00000267615.6
ENST00000553452.1
 ITPK1

inositol-tetrakisphosphate 1-kinase

chr16_-_11681023 0.018 ENST00000570904.1
ENST00000574701.1
 LITAF

lipopolysaccharide-induced TNF factor

chr3_-_195808980 0.017 ENST00000360110.4
 TFRC
transferrin receptor
chr4_-_78740511 0.016 ENST00000504123.1
ENST00000264903.4
ENST00000515441.1
 CNOT6L


CCR4-NOT transcription complex, subunit 6-like


chr9_+_112542591 0.016 ENST00000413420.1
ENST00000302798.7
ENST00000555236.1
ENST00000510514.5
ENST00000483909.1
ENST00000314527.4
 PALM2-AKAP2

AKAP2

PALM2

PALM2-AKAP2 readthrough

A kinase (PRKA) anchor protein 2

paralemmin 2

chr19_+_45582453 0.016 ENST00000587566.1
ENST00000591607.1
ENST00000591747.1
ENST00000270257.4
ENST00000391951.2
 MARK4
GEMIN7



MAP/microtubule affinity-regulating kinase 4
gem (nuclear organelle) associated protein 7



chr7_+_150748288 0.015 ENST00000490540.1
 ASIC3
acid-sensing (proton-gated) ion channel 3
chr4_+_128982490 0.015 ENST00000394288.3
ENST00000432347.2
ENST00000264584.5
ENST00000441387.1
ENST00000427266.1
ENST00000354456.3
 LARP1B





La ribonucleoprotein domain family, member 1B





chr5_+_176057663 0.015 ENST00000318682.6
 EIF4E1B
eukaryotic translation initiation factor 4E family member 1B
chr10_-_100027943 0.014 ENST00000260702.3
 LOXL4
lysyl oxidase-like 4
chr1_-_35658736 0.013 ENST00000357214.5
 SFPQ
splicing factor proline/glutamine-rich
chr8_+_22423219 0.013 ENST00000523965.1
ENST00000521554.1
 SORBS3

sorbin and SH3 domain containing 3

chr5_-_176057518 0.013 ENST00000393693.2
 SNCB
synuclein, beta
chr3_-_195808952 0.012 ENST00000540528.1
ENST00000392396.3
ENST00000535031.1
ENST00000420415.1
 TFRC



transferrin receptor



chr19_-_38714847 0.012 ENST00000420980.2
ENST00000355526.4
 DPF1

D4, zinc and double PHD fingers family 1

chr8_+_145065705 0.012 ENST00000533044.1
 GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr9_-_124976154 0.012 ENST00000482062.1
 LHX6
LIM homeobox 6
chr5_-_176057365 0.011 ENST00000310112.3
 SNCB
synuclein, beta
chr1_-_165414414 0.011 ENST00000359842.5
 RXRG
retinoid X receptor, gamma
chr20_+_44462749 0.011 ENST00000372541.1
 SNX21
sorting nexin family member 21
chr1_+_1222489 0.011 ENST00000379099.3
 SCNN1D
sodium channel, non-voltage-gated 1, delta subunit
chr20_+_44462430 0.010 ENST00000462307.1
 SNX21
sorting nexin family member 21
chr9_-_130659679 0.010 ENST00000373141.1
 ST6GALNAC6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr7_-_150754935 0.010 ENST00000297518.4
 CDK5
cyclin-dependent kinase 5
chr4_+_128982416 0.010 ENST00000326639.6
 LARP1B
La ribonucleoprotein domain family, member 1B
chr8_+_22423168 0.008 ENST00000518912.1
ENST00000428103.1
 SORBS3

sorbin and SH3 domain containing 3

chr20_+_44462481 0.007 ENST00000491381.1
ENST00000342644.5
ENST00000372542.1
 SNX21


sorting nexin family member 21


chr17_-_73178599 0.006 ENST00000578238.1
 SUMO2
small ubiquitin-like modifier 2
chrX_+_136648643 0.006 ENST00000370606.3
 ZIC3
Zic family member 3
chr6_+_42896865 0.006 ENST00000372836.4
ENST00000394142.3
 CNPY3

canopy FGF signaling regulator 3

chr16_+_3014217 0.006 ENST00000572045.1
 KREMEN2
kringle containing transmembrane protein 2
chr7_+_101460882 0.005 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
 CUX1




cut-like homeobox 1




chr16_+_3014269 0.004 ENST00000575885.1
ENST00000571007.1
ENST00000319500.6
 KREMEN2


kringle containing transmembrane protein 2


chrX_+_136648297 0.004 ENST00000287538.5
 ZIC3
Zic family member 3
chr10_+_17271266 0.004 ENST00000224237.5
 VIM
vimentin
chr10_-_75255668 0.003 ENST00000545874.1
 PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr8_+_145065521 0.003 ENST00000534791.1
 GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr19_-_10450287 0.003 ENST00000589261.1
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
 ICAM3



intercellular adhesion molecule 3



chr4_+_128982430 0.003 ENST00000512292.1
ENST00000508819.1
 LARP1B

La ribonucleoprotein domain family, member 1B

chr7_-_27219849 0.003 ENST00000396344.4
 HOXA10
homeobox A10
chr9_+_116638562 0.002 ENST00000374126.5
ENST00000288466.7
 ZNF618

zinc finger protein 618

chr19_-_10450328 0.002 ENST00000160262.5
 ICAM3
intercellular adhesion molecule 3
chr9_-_130659569 0.001 ENST00000542456.1
 ST6GALNAC6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr2_+_219125714 0.001 ENST00000522678.1
ENST00000519574.1
ENST00000521462.1
 GPBAR1


G protein-coupled bile acid receptor 1


chr19_-_4043154 0.000 ENST00000535853.1
 AC016586.1
AC016586.1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.1 0.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.0 0.1 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.0 0.1 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.5 GO:0034380 high-density lipoprotein particle assembly(GO:0034380)
0.0 0.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.2 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 0.9 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.4 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.1 GO:0005220 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.0 GO:0052726 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport