Motif ID: ZKSCAN3

Z-value: 0.256


Transcription factors associated with ZKSCAN3:

Gene SymbolEntrez IDGene Name
ZKSCAN3 ENSG00000189298.9 ZKSCAN3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZKSCAN3hg19_v2_chr6_+_28317685_283177610.521.5e-01Click!


Activity profile for motif ZKSCAN3.

activity profile for motif ZKSCAN3


Sorted Z-values histogram for motif ZKSCAN3

Sorted Z-values for motif ZKSCAN3



Network of associatons between targets according to the STRING database.



First level regulatory network of ZKSCAN3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_3598871 0.279 ENST00000603362.1
ENST00000604479.1
 TP73

tumor protein p73

chrX_-_153775760 0.121 ENST00000440967.1
ENST00000393564.2
ENST00000369620.2
 G6PD


glucose-6-phosphate dehydrogenase


chrX_-_153775426 0.099 ENST00000393562.2
 G6PD
glucose-6-phosphate dehydrogenase
chr17_+_18625336 0.091 ENST00000395671.4
ENST00000571542.1
ENST00000395672.2
ENST00000414850.2
ENST00000424146.2
 TRIM16L




tripartite motif containing 16-like




chr2_+_191221240 0.082 ENST00000409027.1
ENST00000458193.1
 INPP1

inositol polyphosphate-1-phosphatase

chrX_+_153775869 0.075 ENST00000424839.1
 IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr16_-_28506840 0.071 ENST00000569430.1
 CLN3
ceroid-lipofuscinosis, neuronal 3
chrX_+_153775821 0.070 ENST00000263518.6
ENST00000470142.1
ENST00000393549.2
ENST00000455588.2
ENST00000369602.3
 IKBKG




inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma




chr2_+_191745560 0.061 ENST00000338435.4
 GLS
glutaminase
chr4_-_169239921 0.060 ENST00000514995.1
ENST00000393743.3
 DDX60

DEAD (Asp-Glu-Ala-Asp) box polypeptide 60

chr19_+_39759154 0.054 ENST00000331982.5
 IFNL2
interferon, lambda 2
chr10_+_6779326 0.051 ENST00000417112.1
 RP11-554I8.2
RP11-554I8.2
chr2_-_175351744 0.047 ENST00000295500.4
ENST00000392552.2
ENST00000392551.2
 GPR155


G protein-coupled receptor 155


chr2_-_167232484 0.041 ENST00000375387.4
ENST00000303354.6
ENST00000409672.1
 SCN9A


sodium channel, voltage-gated, type IX, alpha subunit


chr14_+_94492674 0.040 ENST00000203664.5
ENST00000553723.1
 OTUB2

OTU domain, ubiquitin aldehyde binding 2

chr19_+_54372639 0.039 ENST00000391769.2
 MYADM
myeloid-associated differentiation marker
chr22_-_28392227 0.039 ENST00000431039.1
 TTC28
tetratricopeptide repeat domain 28
chr2_+_191745535 0.039 ENST00000320717.3
 GLS
glutaminase
chr10_+_123922941 0.034 ENST00000360561.3
 TACC2
transforming, acidic coiled-coil containing protein 2
chr1_+_93913665 0.033 ENST00000271234.7
ENST00000370256.4
ENST00000260506.8
 FNBP1L


formin binding protein 1-like


chr16_-_1429010 0.031 ENST00000513783.1
 UNKL
unkempt family zinc finger-like
chr5_-_180235755 0.030 ENST00000502678.1
 MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr1_-_935361 0.027 ENST00000484667.2
 HES4
hes family bHLH transcription factor 4
chr19_+_49258775 0.026 ENST00000593756.1
 FGF21
fibroblast growth factor 21
chr1_+_156123359 0.025 ENST00000368284.1
ENST00000368286.2
ENST00000438830.1
 SEMA4A


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A


chr1_+_93913713 0.025 ENST00000604705.1
ENST00000370253.2
 FNBP1L

formin binding protein 1-like

chr7_-_37382683 0.024 ENST00000455879.1
 ELMO1
engulfment and cell motility 1
chr16_-_832054 0.023 ENST00000543963.1
 MSLNL
mesothelin-like
chr3_-_10052849 0.021 ENST00000437616.1
ENST00000429065.2
 AC022007.5

AC022007.5

chr7_+_1084206 0.021 ENST00000444847.1
 GPR146
G protein-coupled receptor 146
chr16_-_745946 0.020 ENST00000562563.1
 FBXL16
F-box and leucine-rich repeat protein 16
chr11_-_61062762 0.019 ENST00000335613.5
 VWCE
von Willebrand factor C and EGF domains
chr5_-_95297534 0.019 ENST00000513343.1
ENST00000431061.2
 ELL2

elongation factor, RNA polymerase II, 2

chr1_-_19811962 0.015 ENST00000375142.1
ENST00000264202.6
 CAPZB

capping protein (actin filament) muscle Z-line, beta

chr16_-_832926 0.015 ENST00000293892.3
 MSLNL
mesothelin-like
chr5_-_114598548 0.015 ENST00000379615.3
ENST00000419445.1
 PGGT1B

protein geranylgeranyltransferase type I, beta subunit

chr1_-_19811996 0.014 ENST00000264203.3
ENST00000401084.2
 CAPZB

capping protein (actin filament) muscle Z-line, beta

chr6_+_116850174 0.013 ENST00000416171.2
ENST00000368597.2
ENST00000452373.1
ENST00000405399.1
 FAM26D



family with sequence similarity 26, member D



chr1_-_28415075 0.013 ENST00000373863.3
ENST00000436342.2
ENST00000540618.1
ENST00000545175.1
 EYA3



eyes absent homolog 3 (Drosophila)



chr1_-_28415204 0.013 ENST00000373871.3
 EYA3
eyes absent homolog 3 (Drosophila)
chr17_+_36908984 0.012 ENST00000225426.4
ENST00000579088.1
 PSMB3

proteasome (prosome, macropain) subunit, beta type, 3

chr7_+_150782945 0.012 ENST00000463381.1
 AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr1_-_19811132 0.012 ENST00000433834.1
 CAPZB
capping protein (actin filament) muscle Z-line, beta
chr19_-_4182497 0.012 ENST00000597896.1
 SIRT6
sirtuin 6
chr17_-_60142609 0.012 ENST00000397786.2
 MED13
mediator complex subunit 13
chr19_-_4182530 0.011 ENST00000601571.1
ENST00000601488.1
ENST00000305232.6
ENST00000381935.3
ENST00000337491.2
 SIRT6




sirtuin 6




chr9_+_127023704 0.011 ENST00000373596.1
ENST00000425237.1
 NEK6

NIMA-related kinase 6

chr1_+_156123318 0.011 ENST00000368285.3
 SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr19_+_52873166 0.010 ENST00000424032.2
ENST00000600321.1
ENST00000344085.5
ENST00000597976.1
ENST00000422689.2
 ZNF880




zinc finger protein 880




chr11_+_66610883 0.008 ENST00000309657.3
ENST00000524506.1
 RCE1

Ras converting CAAX endopeptidase 1

chrX_+_23352133 0.008 ENST00000379361.4
 PTCHD1
patched domain containing 1
chr1_-_86622421 0.008 ENST00000370571.2
 COL24A1
collagen, type XXIV, alpha 1
chrX_-_135338503 0.007 ENST00000370663.5
 MAP7D3
MAP7 domain containing 3
chr15_-_41624685 0.007 ENST00000560640.1
ENST00000220514.3
 OIP5

Opa interacting protein 5

chr5_+_140079919 0.006 ENST00000274712.3
 ZMAT2
zinc finger, matrin-type 2
chr1_+_114472992 0.004 ENST00000514621.1
 HIPK1
homeodomain interacting protein kinase 1
chr19_+_52693259 0.002 ENST00000322088.6
ENST00000454220.2
ENST00000444322.2
ENST00000477989.1
 PPP2R1A



protein phosphatase 2, regulatory subunit A, alpha



chr22_-_50312052 0.002 ENST00000330817.6
 ALG12
ALG12, alpha-1,6-mannosyltransferase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.3 GO:0060044 negative regulation of JUN kinase activity(GO:0043508) negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)