Motif ID: VENTX

Z-value: 0.237


Transcription factors associated with VENTX:

Gene SymbolEntrez IDGene Name
VENTX ENSG00000151650.7 VENTX

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
VENTXhg19_v2_chr10_+_135050908_1350509080.225.7e-01Click!


Activity profile for motif VENTX.

activity profile for motif VENTX


Sorted Z-values histogram for motif VENTX

Sorted Z-values for motif VENTX



Network of associatons between targets according to the STRING database.



First level regulatory network of VENTX

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_52695617 0.391 ENST00000293525.5
 KRT86
keratin 86
chr7_-_81635106 0.233 ENST00000443883.1
 CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr4_+_169013666 0.208 ENST00000359299.3
 ANXA10
annexin A10
chrX_+_105937068 0.208 ENST00000324342.3
 RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr1_-_23886285 0.206 ENST00000374561.5
 ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr2_-_145277569 0.153 ENST00000303660.4
 ZEB2
zinc finger E-box binding homeobox 2
chrX_+_105936982 0.152 ENST00000418562.1
 RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr4_+_86525299 0.138 ENST00000512201.1
 ARHGAP24
Rho GTPase activating protein 24
chr10_-_56561022 0.127 ENST00000373965.2
ENST00000414778.1
ENST00000395438.1
ENST00000409834.1
ENST00000395445.1
ENST00000395446.1
ENST00000395442.1
ENST00000395440.1
ENST00000395432.2
ENST00000361849.3
ENST00000395433.1
ENST00000320301.6
ENST00000395430.1
ENST00000437009.1
 PCDH15













protocadherin-related 15













chr2_-_145188137 0.119 ENST00000440875.1
 ZEB2
zinc finger E-box binding homeobox 2
chr5_+_95066823 0.112 ENST00000506817.1
ENST00000379982.3
 RHOBTB3

Rho-related BTB domain containing 3

chr8_+_92261516 0.111 ENST00000276609.3
ENST00000309536.2
 SLC26A7

solute carrier family 26 (anion exchanger), member 7

chr4_+_37455536 0.108 ENST00000381980.4
ENST00000508175.1
 C4orf19

chromosome 4 open reading frame 19

chrX_+_106163626 0.105 ENST00000336803.1
 CLDN2
claudin 2
chr8_+_31496809 0.101 ENST00000518104.1
ENST00000519301.1
 NRG1

neuregulin 1

chr5_-_115890554 0.093 ENST00000509665.1
 SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr1_-_232651312 0.092 ENST00000262861.4
 SIPA1L2
signal-induced proliferation-associated 1 like 2
chr8_-_109799793 0.091 ENST00000297459.3
 TMEM74
transmembrane protein 74
chr17_-_29645836 0.082 ENST00000578584.1
 CTD-2370N5.3
CTD-2370N5.3
chr7_+_148287657 0.076 ENST00000307003.2
 C7orf33
chromosome 7 open reading frame 33
chr2_+_226265364 0.073 ENST00000272907.6
 NYAP2
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
chr10_+_24738355 0.072 ENST00000307544.6
 KIAA1217
KIAA1217
chr3_+_185303962 0.070 ENST00000296257.5
 SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr12_+_56473939 0.070 ENST00000450146.2
 ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr12_+_56473910 0.069 ENST00000411731.2
 ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr4_+_86748898 0.066 ENST00000509300.1
 ARHGAP24
Rho GTPase activating protein 24
chr17_-_202579 0.066 ENST00000577079.1
ENST00000331302.7
ENST00000536489.2
 RPH3AL


rabphilin 3A-like (without C2 domains)


chr7_+_129984630 0.064 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
 CPA5








carboxypeptidase A5








chr13_-_67802549 0.064 ENST00000328454.5
ENST00000377865.2
 PCDH9

protocadherin 9

chr6_+_101847105 0.062 ENST00000369137.3
ENST00000318991.6
 GRIK2

glutamate receptor, ionotropic, kainate 2

chr5_-_124081008 0.062 ENST00000306315.5
 ZNF608
zinc finger protein 608
chr4_-_168155169 0.061 ENST00000534949.1
ENST00000535728.1
 SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr1_+_174417095 0.060 ENST00000367685.2
 GPR52
G protein-coupled receptor 52
chr4_-_84035905 0.059 ENST00000311507.4
 PLAC8
placenta-specific 8
chr3_+_134514093 0.057 ENST00000398015.3
 EPHB1
EPH receptor B1
chr4_-_84035868 0.056 ENST00000426923.2
ENST00000509973.1
 PLAC8

placenta-specific 8

chr1_+_78470530 0.050 ENST00000370763.5
 DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr1_+_244515930 0.049 ENST00000366537.1
ENST00000308105.4
 C1orf100

chromosome 1 open reading frame 100

chr12_-_45269251 0.049 ENST00000553120.1
 NELL2
NEL-like 2 (chicken)
chr4_+_86749045 0.047 ENST00000514229.1
 ARHGAP24
Rho GTPase activating protein 24
chr8_+_26150628 0.046 ENST00000523925.1
ENST00000315985.7
 PPP2R2A

protein phosphatase 2, regulatory subunit B, alpha

chrX_+_55478538 0.044 ENST00000342972.1
 MAGEH1
melanoma antigen family H, 1
chr9_+_116225999 0.043 ENST00000317613.6
 RGS3
regulator of G-protein signaling 3
chr5_-_156486120 0.043 ENST00000522693.1
 HAVCR1
hepatitis A virus cellular receptor 1
chr4_-_105416039 0.041 ENST00000394767.2
 CXXC4
CXXC finger protein 4
chr7_-_107880508 0.040 ENST00000425651.2
 NRCAM
neuronal cell adhesion molecule
chr3_+_50211240 0.039 ENST00000420831.1
 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr4_+_105828492 0.039 ENST00000506148.1
 RP11-556I14.1
RP11-556I14.1
chr6_+_101846664 0.038 ENST00000421544.1
ENST00000413795.1
ENST00000369138.1
ENST00000358361.3
 GRIK2



glutamate receptor, ionotropic, kainate 2



chr15_-_33180439 0.037 ENST00000559610.1
 FMN1
formin 1
chr2_-_164592497 0.037 ENST00000333129.3
ENST00000409634.1
 FIGN

fidgetin

chr2_+_177015122 0.036 ENST00000468418.3
 HOXD3
homeobox D3
chr20_-_25371412 0.035 ENST00000339157.5
ENST00000376542.3
 ABHD12

abhydrolase domain containing 12

chr4_+_71587669 0.035 ENST00000381006.3
ENST00000226328.4
 RUFY3

RUN and FYVE domain containing 3

chr12_+_25205568 0.034 ENST00000548766.1
ENST00000556887.1
 LRMP

lymphoid-restricted membrane protein

chr8_-_42358742 0.034 ENST00000517366.1
 SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr12_+_25205446 0.033 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
 LRMP


lymphoid-restricted membrane protein


chr6_+_34204642 0.032 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
 HMGA1




high mobility group AT-hook 1




chr6_+_126221034 0.031 ENST00000433571.1
 NCOA7
nuclear receptor coactivator 7
chr6_-_32157947 0.031 ENST00000375050.4
 PBX2
pre-B-cell leukemia homeobox 2
chr20_+_42523336 0.029 ENST00000428529.1
 RP5-1030M6.3
RP5-1030M6.3
chr11_-_111649074 0.029 ENST00000534218.1
 RP11-108O10.2
RP11-108O10.2
chr10_-_56560939 0.028 ENST00000373955.1
 PCDH15
protocadherin-related 15
chr7_+_148982396 0.028 ENST00000418158.2
 ZNF783
zinc finger family member 783
chr18_+_13465008 0.028 ENST00000593236.1
 LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr4_-_46126093 0.027 ENST00000295452.4
 GABRG1
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr5_-_142780280 0.027 ENST00000424646.2
 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr6_-_66417107 0.027 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
 EYS



eyes shut homolog (Drosophila)



chr1_+_203651937 0.026 ENST00000341360.2
 ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr14_-_82000140 0.026 ENST00000555824.1
ENST00000557372.1
ENST00000336735.4
 SEL1L


sel-1 suppressor of lin-12-like (C. elegans)


chr11_-_124981475 0.026 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
 TMEM218











transmembrane protein 218











chr2_-_166060382 0.025 ENST00000409101.3
 SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr12_-_2113583 0.025 ENST00000397173.4
ENST00000280665.6
 DCP1B

decapping mRNA 1B

chr4_+_129732419 0.025 ENST00000510308.1
 PHF17
jade family PHD finger 1
chr4_+_169418195 0.025 ENST00000261509.6
ENST00000335742.7
 PALLD

palladin, cytoskeletal associated protein

chr2_-_203776864 0.025 ENST00000261015.4
 WDR12
WD repeat domain 12
chr12_-_89746264 0.024 ENST00000548755.1
 DUSP6
dual specificity phosphatase 6
chr12_-_101604185 0.024 ENST00000536262.2
 SLC5A8
solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8
chr5_+_102201722 0.024 ENST00000274392.9
ENST00000455264.2
 PAM

peptidylglycine alpha-amidating monooxygenase

chr4_-_122148620 0.023 ENST00000509841.1
 TNIP3
TNFAIP3 interacting protein 3
chr2_+_149402989 0.021 ENST00000397424.2
 EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr18_+_20714525 0.020 ENST00000400473.2
 CABLES1
Cdk5 and Abl enzyme substrate 1
chr10_-_33405600 0.019 ENST00000414308.1
 RP11-342D11.3
RP11-342D11.3
chr9_+_136501478 0.018 ENST00000393056.2
ENST00000263611.2
 DBH

dopamine beta-hydroxylase (dopamine beta-monooxygenase)

chr18_-_24237339 0.018 ENST00000580191.1
 KCTD1
potassium channel tetramerization domain containing 1
chr12_-_89746173 0.017 ENST00000308385.6
 DUSP6
dual specificity phosphatase 6
chr12_+_25205666 0.017 ENST00000547044.1
 LRMP
lymphoid-restricted membrane protein
chr16_+_69984810 0.016 ENST00000393701.2
ENST00000568461.1
 CLEC18A

C-type lectin domain family 18, member A

chr3_-_27764190 0.015 ENST00000537516.1
 EOMES
eomesodermin
chr16_+_69985083 0.015 ENST00000288040.6
ENST00000449317.2
 CLEC18A

C-type lectin domain family 18, member A

chr1_-_190446759 0.015 ENST00000367462.3
 BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr5_-_130500922 0.015 ENST00000513012.1
ENST00000508488.1
ENST00000506908.1
ENST00000304043.5
 HINT1



histidine triad nucleotide binding protein 1



chr7_-_82792215 0.015 ENST00000333891.9
ENST00000423517.2
 PCLO

piccolo presynaptic cytomatrix protein

chr2_-_224467093 0.014 ENST00000305409.2
 SCG2
secretogranin II
chr4_+_169418255 0.014 ENST00000505667.1
ENST00000511948.1
 PALLD

palladin, cytoskeletal associated protein

chr12_+_27398584 0.014 ENST00000543246.1
 STK38L
serine/threonine kinase 38 like
chr12_-_16758059 0.013 ENST00000261169.6
 LMO3
LIM domain only 3 (rhombotin-like 2)
chr6_+_37897735 0.012 ENST00000373389.5
 ZFAND3
zinc finger, AN1-type domain 3
chr10_-_28571015 0.012 ENST00000375719.3
ENST00000375732.1
 MPP7

membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)

chr7_-_78400598 0.012 ENST00000536571.1
 MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr8_-_7220490 0.012 ENST00000400078.2
 ZNF705G
zinc finger protein 705G
chrX_+_78003204 0.012 ENST00000435339.3
ENST00000514744.1
 LPAR4

lysophosphatidic acid receptor 4

chr17_-_39203519 0.012 ENST00000542137.1
ENST00000391419.3
 KRTAP2-1

keratin associated protein 2-1

chr5_+_61874696 0.011 ENST00000491184.2
 LRRC70
leucine rich repeat containing 70
chr1_-_178840157 0.011 ENST00000367629.1
ENST00000234816.2
 ANGPTL1

angiopoietin-like 1

chr3_-_57233966 0.011 ENST00000473921.1
ENST00000295934.3
 HESX1

HESX homeobox 1

chr10_+_68685764 0.011 ENST00000361320.4
 LRRTM3
leucine rich repeat transmembrane neuronal 3
chr2_+_159825143 0.010 ENST00000454300.1
ENST00000263635.6
 TANC1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr20_+_42136308 0.010 ENST00000434666.1
ENST00000427442.2
ENST00000439769.1
ENST00000418998.1
 L3MBTL1



l(3)mbt-like 1 (Drosophila)



chr1_+_62439037 0.010 ENST00000545929.1
 INADL
InaD-like (Drosophila)
chr4_+_129732467 0.010 ENST00000413543.2
 PHF17
jade family PHD finger 1
chr4_+_123161120 0.010 ENST00000446180.1
 KIAA1109
KIAA1109
chr15_+_34261089 0.010 ENST00000383263.5
 CHRM5
cholinergic receptor, muscarinic 5
chr2_-_165698521 0.009 ENST00000409184.3
ENST00000392717.2
ENST00000456693.1
 COBLL1


cordon-bleu WH2 repeat protein-like 1


chr17_+_39845134 0.009 ENST00000591776.1
ENST00000469257.1
 EIF1

eukaryotic translation initiation factor 1

chr5_+_60933634 0.009 ENST00000505642.1
 C5orf64
chromosome 5 open reading frame 64
chr6_+_153552455 0.009 ENST00000392385.2
 AL590867.1
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr12_+_64798826 0.009 ENST00000540203.1
 XPOT
exportin, tRNA
chr2_+_203776937 0.009 ENST00000402905.3
ENST00000414490.1
ENST00000431787.1
ENST00000444724.1
ENST00000414857.1
ENST00000430899.1
ENST00000445120.1
ENST00000441569.1
ENST00000432024.1
ENST00000443740.1
ENST00000414439.1
ENST00000428585.1
ENST00000545253.1
ENST00000545262.1
ENST00000447539.1
ENST00000456821.2
ENST00000434998.1
ENST00000320443.8
 CARF

















calcium responsive transcription factor

















chr7_-_78400364 0.009 ENST00000535697.1
 MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_-_224467002 0.009 ENST00000421386.1
ENST00000433889.1
 SCG2

secretogranin II

chr22_+_42834029 0.009 ENST00000428765.1
 CTA-126B4.7
CTA-126B4.7
chr16_-_74455290 0.009 ENST00000339953.5
 CLEC18B
C-type lectin domain family 18, member B
chr2_-_165698662 0.008 ENST00000194871.6
ENST00000445474.2
 COBLL1

cordon-bleu WH2 repeat protein-like 1

chr17_+_43239231 0.008 ENST00000591576.1
ENST00000591070.1
ENST00000592695.1
 HEXIM2


hexamethylene bis-acetamide inducible 2


chr11_-_11374904 0.008 ENST00000528848.2
 CSNK2A3
casein kinase 2, alpha 3 polypeptide
chrX_+_135730297 0.008 ENST00000370629.2
 CD40LG
CD40 ligand
chr11_+_64018955 0.007 ENST00000279230.6
ENST00000540288.1
ENST00000325234.5
 PLCB3


phospholipase C, beta 3 (phosphatidylinositol-specific)


chr11_-_18211042 0.007 ENST00000527671.1
 RP11-113D6.6
Uncharacterized protein
chr1_+_150337100 0.007 ENST00000401000.4
 RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr12_-_53994805 0.007 ENST00000328463.7
 ATF7
activating transcription factor 7
chr3_+_171561127 0.007 ENST00000334567.5
ENST00000450693.1
 TMEM212

transmembrane protein 212

chr18_+_59000815 0.006 ENST00000262717.4
 CDH20
cadherin 20, type 2
chr1_+_226411319 0.006 ENST00000542034.1
ENST00000366810.5
 MIXL1

Mix paired-like homeobox

chr12_+_70219052 0.006 ENST00000552032.2
ENST00000547771.2
 MYRFL

myelin regulatory factor-like

chr11_+_75526212 0.006 ENST00000356136.3
 UVRAG
UV radiation resistance associated
chr22_-_40929812 0.006 ENST00000422851.1
 MKL1
megakaryoblastic leukemia (translocation) 1
chr6_-_76203345 0.006 ENST00000393004.2
 FILIP1
filamin A interacting protein 1
chr7_-_22234381 0.006 ENST00000458533.1
 RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chrX_+_135730373 0.006 ENST00000370628.2
 CD40LG
CD40 ligand
chr17_-_39222131 0.005 ENST00000394015.2
 KRTAP2-4
keratin associated protein 2-4
chr8_+_50824233 0.005 ENST00000522124.1
 SNTG1
syntrophin, gamma 1
chrX_-_46187069 0.004 ENST00000446884.1
 RP1-30G7.2
RP1-30G7.2
chr11_+_35198118 0.004 ENST00000525211.1
ENST00000526000.1
ENST00000279452.6
ENST00000527889.1
 CD44



CD44 molecule (Indian blood group)



chr12_-_53012343 0.004 ENST00000305748.3
 KRT73
keratin 73
chr1_+_28527070 0.004 ENST00000596102.1
 AL353354.2
AL353354.2
chr7_+_139025875 0.004 ENST00000297534.6
 C7orf55
chromosome 7 open reading frame 55
chr2_+_166152283 0.004 ENST00000375427.2
 SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr12_+_25205155 0.003 ENST00000550945.1
 LRMP
lymphoid-restricted membrane protein
chr1_+_150337144 0.003 ENST00000539519.1
ENST00000369067.3
ENST00000369068.4
 RPRD2


regulation of nuclear pre-mRNA domain containing 2


chr1_-_152061537 0.003 ENST00000368806.1
 TCHHL1
trichohyalin-like 1
chr11_-_111649015 0.003 ENST00000529841.1
 RP11-108O10.2
RP11-108O10.2
chr5_-_41794313 0.002 ENST00000512084.1
 OXCT1
3-oxoacid CoA transferase 1
chr11_-_107729887 0.002 ENST00000525815.1
 SLC35F2
solute carrier family 35, member F2
chr11_-_3859089 0.002 ENST00000396979.1
 RHOG
ras homolog family member G
chr1_+_162351503 0.002 ENST00000458626.2
 C1orf226
chromosome 1 open reading frame 226
chr1_-_102312517 0.002 ENST00000338858.5
 OLFM3
olfactomedin 3
chr5_-_41794663 0.001 ENST00000510634.1
 OXCT1
3-oxoacid CoA transferase 1
chr11_-_107729287 0.001 ENST00000375682.4
 SLC35F2
solute carrier family 35, member F2
chr11_-_64684672 0.000 ENST00000377264.3
ENST00000421419.2
 ATG2A

autophagy related 2A

chr5_+_65222500 0.000 ENST00000511297.1
ENST00000506030.1
 ERBB2IP

erbb2 interacting protein


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:1902748 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.2 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.4 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631) inactivation of MAPKK activity(GO:0051389)
0.0 0.1 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)