Motif ID: TP63

Z-value: 0.423


Transcription factors associated with TP63:

Gene SymbolEntrez IDGene Name
TP63 ENSG00000073282.8 TP63

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TP63hg19_v2_chr3_+_189507432_189507459-0.442.3e-01Click!


Activity profile for motif TP63.

activity profile for motif TP63


Sorted Z-values histogram for motif TP63

Sorted Z-values for motif TP63



Network of associatons between targets according to the STRING database.



First level regulatory network of TP63

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_9880412 0.470 ENST00000418909.2
SHROOM2
shroom family member 2
chrX_+_3189861 0.454 ENST00000457435.1
ENST00000420429.2
CXorf28

chromosome X open reading frame 28

chr12_-_96184533 0.429 ENST00000343702.4
ENST00000344911.4
NTN4

netrin 4

chr8_+_21881636 0.402 ENST00000520125.1
ENST00000521157.1
ENST00000397940.1
ENST00000522813.1
NPM2



nucleophosmin/nucleoplasmin 2



chrX_+_9880590 0.384 ENST00000452575.1
SHROOM2
shroom family member 2
chr10_-_21463116 0.336 ENST00000417816.2
NEBL
nebulette
chr1_+_3607228 0.330 ENST00000378285.1
ENST00000378280.1
ENST00000378288.4
TP73


tumor protein p73


chr18_+_61143994 0.287 ENST00000382771.4
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr10_-_105212059 0.277 ENST00000260743.5
CALHM2
calcium homeostasis modulator 2
chr12_-_96184913 0.274 ENST00000538383.1
NTN4
netrin 4
chr10_-_105212141 0.262 ENST00000369788.3
CALHM2
calcium homeostasis modulator 2
chr6_-_46922659 0.256 ENST00000265417.7
GPR116
G protein-coupled receptor 116
chr20_-_52790512 0.248 ENST00000216862.3
CYP24A1
cytochrome P450, family 24, subfamily A, polypeptide 1
chr19_+_51293672 0.245 ENST00000270593.1
ENST00000270594.3
ACPT

acid phosphatase, testicular

chr19_+_12305824 0.240 ENST00000415793.1
ENST00000440004.1
ENST00000426044.1
CTD-2666L21.1


CTD-2666L21.1


chr6_+_121756809 0.235 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr19_-_5292781 0.234 ENST00000586065.1
PTPRS
protein tyrosine phosphatase, receptor type, S
chr4_+_72204755 0.230 ENST00000512686.1
ENST00000340595.3
SLC4A4

solute carrier family 4 (sodium bicarbonate cotransporter), member 4

chr16_+_19467772 0.222 ENST00000219821.5
ENST00000561503.1
ENST00000564959.1
TMC5


transmembrane channel-like 5


chr20_-_23807358 0.222 ENST00000304725.2
CST2
cystatin SA
chr5_+_109218883 0.211 ENST00000523446.1
AC011366.3
Uncharacterized protein
chr5_-_160365601 0.209 ENST00000518580.1
ENST00000518301.1
RP11-109J4.1

RP11-109J4.1

chr7_-_1600433 0.200 ENST00000431208.1
TMEM184A
transmembrane protein 184A
chr19_+_18496957 0.199 ENST00000252809.3
GDF15
growth differentiation factor 15
chr20_-_23669590 0.193 ENST00000217423.3
CST4
cystatin S
chr5_-_67730240 0.189 ENST00000507733.1
CTC-537E7.3
CTC-537E7.3
chr3_-_167813672 0.184 ENST00000470487.1
GOLIM4
golgi integral membrane protein 4
chr19_-_5293243 0.183 ENST00000591760.1
PTPRS
protein tyrosine phosphatase, receptor type, S
chr8_-_18942240 0.182 ENST00000521475.1
PSD3
pleckstrin and Sec7 domain containing 3
chr10_-_90751038 0.177 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2


actin, alpha 2, smooth muscle, aorta


chr11_-_104972158 0.173 ENST00000598974.1
ENST00000593315.1
ENST00000594519.1
ENST00000415981.2
ENST00000525374.1
ENST00000375707.1
CASP1



CARD16
CARD17
caspase 1, apoptosis-related cysteine peptidase



caspase recruitment domain family, member 16
caspase recruitment domain family, member 17
chr16_+_57653989 0.173 ENST00000567835.1
ENST00000569372.1
ENST00000563548.1
ENST00000562003.1
GPR56



G protein-coupled receptor 56



chr16_+_57653854 0.169 ENST00000568908.1
ENST00000568909.1
ENST00000566778.1
ENST00000561988.1
GPR56



G protein-coupled receptor 56



chr9_+_91606355 0.165 ENST00000358157.2
S1PR3
sphingosine-1-phosphate receptor 3
chr4_+_95916947 0.163 ENST00000506363.1
BMPR1B
bone morphogenetic protein receptor, type IB
chrX_-_45710920 0.161 ENST00000456532.1
RP5-1158E12.3
RP5-1158E12.3
chr1_-_47655686 0.157 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr10_+_90750493 0.151 ENST00000357339.2
ENST00000355279.2
FAS

Fas cell surface death receptor

chr18_+_61144160 0.151 ENST00000489441.1
ENST00000424602.1
SERPINB5

serpin peptidase inhibitor, clade B (ovalbumin), member 5

chr4_-_40516560 0.148 ENST00000513473.1
RBM47
RNA binding motif protein 47
chrX_-_8700171 0.136 ENST00000262648.3
KAL1
Kallmann syndrome 1 sequence
chr1_+_236558694 0.133 ENST00000359362.5
EDARADD
EDAR-associated death domain
chr4_+_95917383 0.132 ENST00000512312.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr14_-_98444438 0.130 ENST00000512901.2
C14orf64
chromosome 14 open reading frame 64
chr9_-_139637355 0.128 ENST00000474369.1
ENST00000497771.1
ENST00000527229.1
LCN10


lipocalin 10


chr16_+_57653625 0.122 ENST00000567553.1
ENST00000565314.1
GPR56

G protein-coupled receptor 56

chr19_+_12305895 0.122 ENST00000451691.2
CTD-2666L21.1
CTD-2666L21.1
chr1_-_32801825 0.121 ENST00000329421.7
MARCKSL1
MARCKS-like 1
chr3_+_184081213 0.119 ENST00000429568.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr11_+_5712234 0.117 ENST00000414641.1
TRIM22
tripartite motif containing 22
chr3_+_184081137 0.115 ENST00000443489.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr3_+_184081175 0.114 ENST00000452961.1
ENST00000296223.3
POLR2H

polymerase (RNA) II (DNA directed) polypeptide H

chr11_-_68611721 0.114 ENST00000561996.1
CPT1A
carnitine palmitoyltransferase 1A (liver)
chr6_-_30712313 0.113 ENST00000376377.2
ENST00000259874.5
IER3

immediate early response 3

chr9_+_124088860 0.113 ENST00000373806.1
GSN
gelsolin
chr2_+_217524323 0.112 ENST00000456764.1
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr11_-_10920714 0.109 ENST00000533941.1
CTD-2003C8.2
CTD-2003C8.2
chr3_+_184080387 0.108 ENST00000455712.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr5_+_179247759 0.106 ENST00000389805.4
ENST00000504627.1
ENST00000402874.3
ENST00000510187.1
SQSTM1



sequestosome 1



chr16_+_58010339 0.105 ENST00000290871.5
ENST00000441824.2
TEPP

testis, prostate and placenta expressed

chr8_+_74206829 0.103 ENST00000240285.5
RDH10
retinol dehydrogenase 10 (all-trans)
chr2_+_112813134 0.100 ENST00000452614.1
TMEM87B
transmembrane protein 87B
chr1_+_20959943 0.096 ENST00000321556.4
PINK1
PTEN induced putative kinase 1
chr2_-_216003127 0.095 ENST00000412081.1
ENST00000272895.7
ABCA12

ATP-binding cassette, sub-family A (ABC1), member 12

chr15_+_69365272 0.095 ENST00000559914.1
ENST00000558369.1
LINC00277

long intergenic non-protein coding RNA 277

chr19_+_8483272 0.095 ENST00000602117.1
MARCH2
membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
chr18_+_57567180 0.094 ENST00000316660.6
ENST00000269518.9
PMAIP1

phorbol-12-myristate-13-acetate-induced protein 1

chr3_-_184971817 0.093 ENST00000440662.1
ENST00000456310.1
EHHADH

enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase

chr14_+_35514323 0.091 ENST00000555211.1
FAM177A1
family with sequence similarity 177, member A1
chr7_+_72742178 0.091 ENST00000442793.1
ENST00000413573.2
ENST00000252037.4
FKBP6


FK506 binding protein 6, 36kDa


chr16_+_57653596 0.089 ENST00000568791.1
ENST00000570044.1
GPR56

G protein-coupled receptor 56

chr11_+_76493294 0.088 ENST00000533752.1
TSKU
tsukushi, small leucine rich proteoglycan
chr3_+_69915385 0.088 ENST00000314589.5
MITF
microphthalmia-associated transcription factor
chr12_-_52887034 0.085 ENST00000330722.6
KRT6A
keratin 6A
chr10_+_11059826 0.085 ENST00000450189.1
CELF2
CUGBP, Elav-like family member 2
chr2_-_178257401 0.083 ENST00000464747.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr12_-_88974236 0.083 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG


KIT ligand


chr19_-_12476443 0.083 ENST00000242804.4
ENST00000438182.1
ZNF442

zinc finger protein 442

chr2_-_179315786 0.080 ENST00000457633.1
ENST00000438687.3
ENST00000325748.4
PRKRA


protein kinase, interferon-inducible double stranded RNA dependent activator


chr8_-_67341208 0.079 ENST00000499642.1
RP11-346I3.4
RP11-346I3.4
chr6_-_33663474 0.079 ENST00000594414.1
SBP1
SBP1; Uncharacterized protein
chr5_-_156486120 0.079 ENST00000522693.1
HAVCR1
hepatitis A virus cellular receptor 1
chr15_+_55700741 0.078 ENST00000569691.1
C15orf65
chromosome 15 open reading frame 65
chr1_+_26485511 0.077 ENST00000374268.3
FAM110D
family with sequence similarity 110, member D
chr11_-_104905840 0.077 ENST00000526568.1
ENST00000393136.4
ENST00000531166.1
ENST00000534497.1
ENST00000527979.1
ENST00000446369.1
ENST00000353247.5
ENST00000528974.1
ENST00000533400.1
ENST00000525825.1
ENST00000436863.3
CASP1










caspase 1, apoptosis-related cysteine peptidase










chr1_+_12040238 0.076 ENST00000444836.1
ENST00000235329.5
MFN2

mitofusin 2

chr3_+_69915363 0.076 ENST00000451708.1
MITF
microphthalmia-associated transcription factor
chr3_-_167098059 0.076 ENST00000392764.1
ENST00000474464.1
ENST00000392766.2
ENST00000485651.1
ZBBX



zinc finger, B-box domain containing



chr6_-_152957944 0.076 ENST00000423061.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr2_-_151344172 0.075 ENST00000375734.2
ENST00000263895.4
ENST00000454202.1
RND3


Rho family GTPase 3


chr6_-_10747802 0.075 ENST00000606522.1
ENST00000606652.1
RP11-421M1.8

RP11-421M1.8

chr2_+_198365122 0.075 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr12_+_49687425 0.074 ENST00000257860.4
PRPH
peripherin
chr8_+_29953163 0.073 ENST00000518192.1
LEPROTL1
leptin receptor overlapping transcript-like 1
chr6_+_54711533 0.072 ENST00000306858.7
FAM83B
family with sequence similarity 83, member B
chr5_-_94417314 0.071 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr5_-_94417339 0.070 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1


multiple C2 domains, transmembrane 1


chr11_+_64073699 0.069 ENST00000405666.1
ENST00000468670.1
ESRRA

estrogen-related receptor alpha

chr15_+_41136216 0.069 ENST00000562057.1
ENST00000344051.4
SPINT1

serine peptidase inhibitor, Kunitz type 1

chr7_+_72742162 0.068 ENST00000431982.2
FKBP6
FK506 binding protein 6, 36kDa
chr9_+_35906176 0.068 ENST00000354323.2
HRCT1
histidine rich carboxyl terminus 1
chr5_-_94417562 0.066 ENST00000505465.1
MCTP1
multiple C2 domains, transmembrane 1
chr14_+_39703084 0.065 ENST00000553728.1
RP11-407N17.3
cTAGE family member 5 isoform 4
chr7_-_139756791 0.065 ENST00000489809.1
PARP12
poly (ADP-ribose) polymerase family, member 12
chr6_-_33385902 0.065 ENST00000374500.5
CUTA
cutA divalent cation tolerance homolog (E. coli)
chr8_+_29952914 0.064 ENST00000321250.8
ENST00000518001.1
ENST00000520682.1
ENST00000442880.2
ENST00000523116.1
LEPROTL1




leptin receptor overlapping transcript-like 1




chr1_+_154300217 0.063 ENST00000368489.3
ATP8B2
ATPase, aminophospholipid transporter, class I, type 8B, member 2
chr5_+_125798031 0.063 ENST00000502348.1
GRAMD3
GRAM domain containing 3
chr5_-_122758994 0.063 ENST00000306467.5
ENST00000515110.1
CEP120

centrosomal protein 120kDa

chr12_+_69202795 0.063 ENST00000539479.1
ENST00000393415.3
ENST00000523991.1
ENST00000543323.1
ENST00000393416.2
MDM2




MDM2 oncogene, E3 ubiquitin protein ligase




chr15_-_55700216 0.062 ENST00000569205.1
CCPG1
cell cycle progression 1
chr1_-_93426998 0.062 ENST00000370310.4
FAM69A
family with sequence similarity 69, member A
chr12_-_15942503 0.062 ENST00000281172.5
EPS8
epidermal growth factor receptor pathway substrate 8
chr4_-_21546272 0.062 ENST00000509207.1
KCNIP4
Kv channel interacting protein 4
chr19_+_12175596 0.061 ENST00000441304.2
ZNF844
zinc finger protein 844
chr6_+_18387570 0.060 ENST00000259939.3
RNF144B
ring finger protein 144B
chr7_+_79763271 0.060 ENST00000442586.1
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr12_-_52845910 0.059 ENST00000252252.3
KRT6B
keratin 6B
chr15_-_55700522 0.058 ENST00000564092.1
ENST00000310958.6
CCPG1

cell cycle progression 1

chr4_-_8160416 0.058 ENST00000505872.1
ENST00000447017.2
ENST00000341937.5
ENST00000361581.5
ABLIM2



actin binding LIM protein family, member 2



chr11_+_832804 0.057 ENST00000397420.3
ENST00000525718.1
CD151

CD151 molecule (Raph blood group)

chr8_+_22853345 0.057 ENST00000522948.1
RHOBTB2
Rho-related BTB domain containing 2
chr4_+_671711 0.057 ENST00000400159.2
MYL5
myosin, light chain 5, regulatory
chr9_-_116159635 0.056 ENST00000452726.1
ALAD
aminolevulinate dehydratase
chr6_+_31691121 0.055 ENST00000480039.1
ENST00000375810.4
ENST00000375805.2
ENST00000375809.3
ENST00000375804.2
ENST00000375814.3
ENST00000375806.2
C6orf25






chromosome 6 open reading frame 25






chr1_-_3528034 0.055 ENST00000356575.4
MEGF6
multiple EGF-like-domains 6
chr19_-_9811347 0.055 ENST00000585964.1
ENST00000457674.2
ENST00000590544.1
ZNF812


zinc finger protein 812


chr17_+_4618734 0.055 ENST00000571206.1
ARRB2
arrestin, beta 2
chr2_+_169312725 0.054 ENST00000392687.4
CERS6
ceramide synthase 6
chr15_+_69857515 0.054 ENST00000559477.1
RP11-279F6.1
RP11-279F6.1
chr12_+_69202975 0.054 ENST00000544561.1
ENST00000393410.1
ENST00000299252.4
ENST00000360430.2
ENST00000517852.1
ENST00000545204.1
ENST00000393413.3
ENST00000350057.5
ENST00000348801.2
ENST00000478070.1
MDM2









MDM2 oncogene, E3 ubiquitin protein ligase









chr11_-_10920838 0.053 ENST00000503469.2
CTD-2003C8.2
CTD-2003C8.2
chr11_+_65122216 0.053 ENST00000309880.5
TIGD3
tigger transposable element derived 3
chr1_-_152539248 0.053 ENST00000368789.1
LCE3E
late cornified envelope 3E
chr6_+_139135648 0.053 ENST00000541398.1
ECT2L
epithelial cell transforming sequence 2 oncogene-like
chr15_-_55700457 0.052 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
CCPG1


cell cycle progression 1


chr19_-_58400148 0.052 ENST00000595048.1
ENST00000600634.1
ENST00000595295.1
ENST00000596604.1
ENST00000597342.1
ENST00000597807.1
ZNF814





zinc finger protein 814





chr18_-_19283649 0.052 ENST00000584464.1
ENST00000578270.1
ABHD3

abhydrolase domain containing 3

chr12_-_10607084 0.051 ENST00000408006.3
ENST00000544822.1
ENST00000536188.1
KLRC1


killer cell lectin-like receptor subfamily C, member 1


chr19_-_19887185 0.051 ENST00000590092.1
ENST00000589910.1
ENST00000589508.1
ENST00000586645.1
ENST00000586816.1
ENST00000588223.1
ENST00000586885.1
LINC00663






long intergenic non-protein coding RNA 663






chr12_+_119616447 0.051 ENST00000281938.2
HSPB8
heat shock 22kDa protein 8
chr4_+_6784401 0.051 ENST00000425103.1
ENST00000307659.5
KIAA0232

KIAA0232

chr2_+_198365095 0.050 ENST00000409468.1
HSPE1
heat shock 10kDa protein 1
chr5_-_122759032 0.048 ENST00000510582.3
ENST00000328236.5
ENST00000306481.6
ENST00000508442.2
ENST00000395431.2
CEP120




centrosomal protein 120kDa




chr19_-_17375541 0.047 ENST00000252597.3
USHBP1
Usher syndrome 1C binding protein 1
chrX_-_153583257 0.047 ENST00000438732.1
FLNA
filamin A, alpha
chr4_-_186317034 0.046 ENST00000505916.1
LRP2BP
LRP2 binding protein
chr1_-_117753540 0.045 ENST00000328189.3
ENST00000369458.3
VTCN1

V-set domain containing T cell activation inhibitor 1

chr15_+_40532723 0.045 ENST00000558878.1
ENST00000558183.1
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr4_-_47916613 0.045 ENST00000381538.3
ENST00000329043.3
NFXL1

nuclear transcription factor, X-box binding-like 1

chr22_-_50946113 0.044 ENST00000216080.5
ENST00000474879.2
ENST00000380796.3
LMF2


lipase maturation factor 2


chr19_-_12405689 0.044 ENST00000355684.5
ZNF44
zinc finger protein 44
chr2_+_166150541 0.043 ENST00000283256.6
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr11_-_65686586 0.043 ENST00000438576.2
C11orf68
chromosome 11 open reading frame 68
chr17_-_26662464 0.043 ENST00000579419.1
ENST00000585313.1
ENST00000395418.3
ENST00000578985.1
ENST00000577498.1
ENST00000585089.1
ENST00000357896.3
IFT20






intraflagellar transport 20 homolog (Chlamydomonas)






chr2_+_178257372 0.043 ENST00000264167.4
ENST00000409888.1
AGPS

alkylglycerone phosphate synthase

chr19_-_19051103 0.043 ENST00000542541.2
ENST00000433218.2
HOMER3

homer homolog 3 (Drosophila)

chr4_-_47916543 0.043 ENST00000507489.1
NFXL1
nuclear transcription factor, X-box binding-like 1
chr11_+_67776012 0.042 ENST00000539229.1
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr2_+_169312350 0.042 ENST00000305747.6
CERS6
ceramide synthase 6
chr19_-_53426700 0.042 ENST00000596623.1
ZNF888
zinc finger protein 888
chr8_+_67025516 0.041 ENST00000517961.2
AC084082.3
AC084082.3
chr5_-_180235755 0.041 ENST00000502678.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr3_+_32023232 0.041 ENST00000360311.4
ZNF860
zinc finger protein 860
chrX_+_55478538 0.041 ENST00000342972.1
MAGEH1
melanoma antigen family H, 1
chr8_+_22960426 0.041 ENST00000540813.1
TNFRSF10C
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
chr4_+_71554196 0.041 ENST00000254803.2
UTP3
UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
chr10_-_101190202 0.040 ENST00000543866.1
ENST00000370508.5
GOT1

glutamic-oxaloacetic transaminase 1, soluble

chrX_-_84363974 0.040 ENST00000395409.3
ENST00000332921.5
ENST00000509231.1
SATL1


spermidine/spermine N1-acetyl transferase-like 1


chr16_+_32264645 0.039 ENST00000569631.1
ENST00000354614.3
TP53TG3D

TP53 target 3D

chr10_-_89623194 0.039 ENST00000445946.3
KLLN
killin, p53-regulated DNA replication inhibitor
chr9_-_35619539 0.038 ENST00000396757.1
CD72
CD72 molecule
chrX_-_153602991 0.038 ENST00000369850.3
ENST00000422373.1
FLNA

filamin A, alpha

chr2_-_214148921 0.038 ENST00000360083.3
AC079610.2
AC079610.2
chr7_+_45927956 0.038 ENST00000275525.3
ENST00000457280.1
IGFBP1

insulin-like growth factor binding protein 1

chr14_-_46185155 0.037 ENST00000555442.1
RP11-369C8.1
RP11-369C8.1
chr2_+_201987200 0.037 ENST00000425030.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr9_+_101569944 0.037 ENST00000375011.3
GALNT12
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12)
chr11_-_65686496 0.037 ENST00000449692.3
C11orf68
chromosome 11 open reading frame 68
chr1_-_109506036 0.037 ENST00000369976.1
ENST00000356970.2
ENST00000369971.2
ENST00000415331.1
ENST00000357393.4
CLCC1



AKNAD1
chloride channel CLIC-like 1



AKNA domain containing 1
chr3_+_19189946 0.036 ENST00000328405.2
KCNH8
potassium voltage-gated channel, subfamily H (eag-related), member 8
chr2_+_113299990 0.036 ENST00000537335.1
ENST00000417433.2
POLR1B

polymerase (RNA) I polypeptide B, 128kDa

chr3_-_191000172 0.036 ENST00000427544.2
UTS2B
urotensin 2B
chr2_-_47168850 0.036 ENST00000409207.1
MCFD2
multiple coagulation factor deficiency 2
chr9_-_136605042 0.036 ENST00000371872.4
ENST00000298628.5
ENST00000422262.2
SARDH


sarcosine dehydrogenase


chr22_+_36044411 0.036 ENST00000409652.4
APOL6
apolipoprotein L, 6
chr20_+_48807351 0.036 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr2_-_47168906 0.036 ENST00000444761.2
ENST00000409147.1
MCFD2

multiple coagulation factor deficiency 2

chr5_+_153570319 0.036 ENST00000377661.2
GALNT10
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr19_+_12175535 0.035 ENST00000550826.1
ZNF844
zinc finger protein 844
chr5_+_174905532 0.035 ENST00000502393.1
ENST00000506963.1
SFXN1

sideroflexin 1

chr5_+_153570285 0.035 ENST00000425427.2
ENST00000297107.6
GALNT10

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)

chr1_-_26197744 0.035 ENST00000374296.3
PAQR7
progestin and adipoQ receptor family member VII
chr4_-_106629796 0.035 ENST00000416543.1
ENST00000515819.1
ENST00000420368.2
ENST00000503746.1
ENST00000340139.5
ENST00000433009.1
INTS12





integrator complex subunit 12





chr15_+_42696992 0.035 ENST00000561817.1
CAPN3
calpain 3, (p94)
chrX_-_153637612 0.034 ENST00000369807.1
ENST00000369808.3
DNASE1L1

deoxyribonuclease I-like 1

chr19_-_3500635 0.034 ENST00000250937.3
DOHH
deoxyhypusine hydroxylase/monooxygenase
chr19_-_46627914 0.034 ENST00000341415.2
IGFL3
IGF-like family member 3
chr17_-_26662440 0.034 ENST00000578122.1
IFT20
intraflagellar transport 20 homolog (Chlamydomonas)
chr5_+_125935960 0.033 ENST00000297540.4
PHAX
phosphorylated adaptor for RNA export

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0008057 eye pigment granule organization(GO:0008057)
0.1 0.4 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1 0.7 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.3 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.2 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.1 GO:0036482 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.1 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.1 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.2 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.1 GO:0001897 cytolysis by symbiont of host cells(GO:0001897) negative regulation of cytolysis(GO:0045918)
0.0 0.2 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.4 GO:0045836 positive regulation of meiotic nuclear division(GO:0045836)
0.0 0.1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.3 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.0 0.0 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.1 GO:0071284 cellular response to lead ion(GO:0071284)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.0 0.0 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.0 GO:0007497 posterior midgut development(GO:0007497) endothelin receptor signaling pathway(GO:0086100)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.0 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0 0.1 GO:1903788 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.1 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.1 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.0 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.0 0.3 GO:0097179 NLRP1 inflammasome complex(GO:0072558) protease inhibitor complex(GO:0097179)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.9 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.0 0.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.1 GO:0034040 lipid-transporting ATPase activity(GO:0034040)
0.0 0.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.1 GO:1904854 proteasome core complex binding(GO:1904854)
0.0 0.1 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.0 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.0 GO:0019808 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.0 GO:0004962 endothelin receptor activity(GO:0004962)
0.0 0.0 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.0 0.1 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME_RNA_POL_III_CHAIN_ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome