Motif ID: TLX2

Z-value: 0.466


Transcription factors associated with TLX2:

Gene SymbolEntrez IDGene Name
TLX2 ENSG00000115297.9 TLX2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TLX2hg19_v2_chr2_+_74741569_747416200.541.4e-01Click!


Activity profile for motif TLX2.

activity profile for motif TLX2


Sorted Z-values histogram for motif TLX2

Sorted Z-values for motif TLX2



Network of associatons between targets according to the STRING database.



First level regulatory network of TLX2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_29150963 0.447 ENST00000563477.1
RP11-426C22.5
RP11-426C22.5
chr1_+_119957554 0.343 ENST00000543831.1
ENST00000433745.1
ENST00000369416.3
HSD3B2


hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2


chr13_-_88323514 0.296 ENST00000441617.1
MIR4500HG
MIR4500 host gene (non-protein coding)
chr7_-_32111009 0.258 ENST00000396184.3
ENST00000396189.2
ENST00000321453.7
PDE1C


phosphodiesterase 1C, calmodulin-dependent 70kDa


chr11_+_123396528 0.246 ENST00000322282.7
ENST00000529750.1
GRAMD1B

GRAM domain containing 1B

chr7_-_32110451 0.242 ENST00000396191.1
ENST00000396182.2
PDE1C

phosphodiesterase 1C, calmodulin-dependent 70kDa

chr11_-_133826852 0.234 ENST00000533871.2
ENST00000321016.8
IGSF9B

immunoglobulin superfamily, member 9B

chr17_-_46667594 0.234 ENST00000476342.1
ENST00000460160.1
ENST00000472863.1
HOXB3


homeobox B3


chr17_-_46667628 0.228 ENST00000498678.1
HOXB3
homeobox B3
chr6_-_10115007 0.217 ENST00000485268.1
OFCC1
orofacial cleft 1 candidate 1
chr3_-_149051194 0.207 ENST00000470080.1
TM4SF18
transmembrane 4 L six family member 18
chr11_-_26593779 0.206 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr3_-_149051444 0.202 ENST00000296059.2
TM4SF18
transmembrane 4 L six family member 18
chr3_+_124355944 0.197 ENST00000459915.1
KALRN
kalirin, RhoGEF kinase
chr11_-_26593677 0.192 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr19_+_44081344 0.190 ENST00000599207.1
PINLYP
phospholipase A2 inhibitor and LY6/PLAUR domain containing
chr20_+_3024266 0.186 ENST00000245983.2
ENST00000359100.2
ENST00000359987.1
GNRH2


gonadotropin-releasing hormone 2


chr6_+_43968306 0.185 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223


chromosome 6 open reading frame 223


chr9_+_35673853 0.183 ENST00000378357.4
CA9
carbonic anhydrase IX
chr11_-_26593649 0.180 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr5_+_159656437 0.171 ENST00000402432.3
FABP6
fatty acid binding protein 6, ileal
chr1_-_6526192 0.164 ENST00000377782.3
ENST00000351959.5
ENST00000356876.3
TNFRSF25


tumor necrosis factor receptor superfamily, member 25


chr1_+_16083123 0.161 ENST00000510393.1
ENST00000430076.1
FBLIM1

filamin binding LIM protein 1

chr11_+_111808119 0.160 ENST00000531396.1
DIXDC1
DIX domain containing 1
chrX_+_152907913 0.160 ENST00000370167.4
DUSP9
dual specificity phosphatase 9
chr20_+_2795626 0.159 ENST00000603872.1
ENST00000380589.4
C20orf141

chromosome 20 open reading frame 141

chr4_+_120056939 0.159 ENST00000307128.5
MYOZ2
myozenin 2
chr21_-_16437255 0.157 ENST00000400199.1
ENST00000400202.1
NRIP1

nuclear receptor interacting protein 1

chr9_-_79520989 0.157 ENST00000376713.3
ENST00000376718.3
ENST00000428286.1
PRUNE2


prune homolog 2 (Drosophila)


chr20_-_14318248 0.153 ENST00000378053.3
ENST00000341420.4
FLRT3

fibronectin leucine rich transmembrane protein 3

chr21_-_16437126 0.153 ENST00000318948.4
NRIP1
nuclear receptor interacting protein 1
chr6_+_13272904 0.151 ENST00000379335.3
ENST00000379329.1
PHACTR1

phosphatase and actin regulator 1

chr10_+_88718397 0.151 ENST00000372017.3
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr1_-_17304771 0.144 ENST00000375534.3
MFAP2
microfibrillar-associated protein 2
chr12_-_42983478 0.139 ENST00000345127.3
ENST00000547113.1
PRICKLE1

prickle homolog 1 (Drosophila)

chr2_-_72375167 0.135 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chrX_-_31285042 0.134 ENST00000378680.2
ENST00000378723.3
DMD

dystrophin

chr1_+_16083154 0.134 ENST00000375771.1
FBLIM1
filamin binding LIM protein 1
chr1_+_16083098 0.133 ENST00000496928.2
ENST00000508310.1
FBLIM1

filamin binding LIM protein 1

chr14_+_37131058 0.133 ENST00000361487.6
PAX9
paired box 9
chr1_-_6526167 0.131 ENST00000351748.3
ENST00000348333.3
TNFRSF25

tumor necrosis factor receptor superfamily, member 25

chr17_-_70053866 0.130 ENST00000540802.1
RP11-84E24.2
RP11-84E24.2
chr15_-_65398647 0.126 ENST00000502113.2
UBAP1L
ubiquitin associated protein 1-like
chr10_+_64133934 0.124 ENST00000395254.3
ENST00000395255.3
ENST00000410046.3
ZNF365


zinc finger protein 365


chr11_-_8615507 0.123 ENST00000431279.2
ENST00000418597.1
STK33

serine/threonine kinase 33

chr16_+_31404624 0.119 ENST00000389202.2
ITGAD
integrin, alpha D
chr1_-_161279749 0.118 ENST00000533357.1
ENST00000360451.6
ENST00000336559.4
MPZ


myelin protein zero


chr14_-_103589246 0.118 ENST00000558224.1
ENST00000560742.1
LINC00677

long intergenic non-protein coding RNA 677

chr2_-_74607390 0.118 ENST00000413111.1
ENST00000409567.3
ENST00000454119.1
ENST00000361874.3
ENST00000394003.3
DCTN1




dynactin 1




chr3_+_46919235 0.117 ENST00000449590.1
PTH1R
parathyroid hormone 1 receptor
chr13_-_33760216 0.115 ENST00000255486.4
STARD13
StAR-related lipid transfer (START) domain containing 13
chr6_-_31550192 0.114 ENST00000429299.2
ENST00000446745.2
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr14_+_65170820 0.114 ENST00000555982.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr3_-_46608010 0.114 ENST00000395905.3
LRRC2
leucine rich repeat containing 2
chrX_-_31285018 0.112 ENST00000361471.4
DMD
dystrophin
chr10_+_88718314 0.112 ENST00000348795.4
SNCG
synuclein, gamma (breast cancer-specific protein 1)
chr17_-_2169425 0.111 ENST00000570606.1
ENST00000354901.4
SMG6

SMG6 nonsense mediated mRNA decay factor

chr5_+_79331164 0.110 ENST00000350881.2
THBS4
thrombospondin 4
chr22_+_42229100 0.108 ENST00000361204.4
SREBF2
sterol regulatory element binding transcription factor 2
chr6_-_143266297 0.107 ENST00000367603.2
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr12_-_71031185 0.106 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB


protein tyrosine phosphatase, receptor type, B


chr15_+_69745123 0.105 ENST00000260379.6
ENST00000357790.5
ENST00000560274.1
RPLP1


ribosomal protein, large, P1


chr20_+_44746885 0.105 ENST00000372285.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr1_+_205473784 0.103 ENST00000478560.1
ENST00000443813.2
CDK18

cyclin-dependent kinase 18

chr8_-_104153703 0.101 ENST00000521246.1
C8orf56
chromosome 8 open reading frame 56
chr12_-_51740463 0.100 ENST00000293636.1
CELA1
chymotrypsin-like elastase family, member 1
chr11_+_124481361 0.100 ENST00000284288.2
PANX3
pannexin 3
chr20_+_44746939 0.100 ENST00000372276.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr16_-_72206034 0.100 ENST00000537465.1
ENST00000237353.10
PMFBP1

polyamine modulated factor 1 binding protein 1

chrX_-_31284974 0.100 ENST00000378702.4
DMD
dystrophin
chr6_+_106546808 0.100 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr2_+_63816126 0.099 ENST00000454035.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr7_-_84122033 0.098 ENST00000424555.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr2_+_63816269 0.098 ENST00000432309.1
MDH1
malate dehydrogenase 1, NAD (soluble)
chr2_+_63816087 0.097 ENST00000409908.1
ENST00000442225.1
ENST00000409476.1
ENST00000436321.1
MDH1



malate dehydrogenase 1, NAD (soluble)



chr11_+_111807863 0.096 ENST00000440460.2
DIXDC1
DIX domain containing 1
chr1_+_53068020 0.096 ENST00000361314.4
GPX7
glutathione peroxidase 7
chr2_+_63816295 0.095 ENST00000539945.1
ENST00000544381.1
MDH1

malate dehydrogenase 1, NAD (soluble)

chr1_+_205473720 0.095 ENST00000429964.2
ENST00000506784.1
ENST00000360066.2
CDK18


cyclin-dependent kinase 18


chr11_+_62186498 0.094 ENST00000278282.2
SCGB1A1
secretoglobin, family 1A, member 1 (uteroglobin)
chr11_-_8615488 0.093 ENST00000315204.1
ENST00000396672.1
ENST00000396673.1
STK33


serine/threonine kinase 33


chr11_-_8615720 0.093 ENST00000358872.3
ENST00000454443.2
STK33

serine/threonine kinase 33

chr4_+_71384300 0.092 ENST00000504451.1
AMTN
amelotin
chr13_+_60971080 0.092 ENST00000377894.2
TDRD3
tudor domain containing 3
chr13_-_88323218 0.091 ENST00000436290.2
ENST00000453832.2
ENST00000606590.1
MIR4500HG


MIR4500 host gene (non-protein coding)


chr12_-_71031220 0.091 ENST00000334414.6
PTPRB
protein tyrosine phosphatase, receptor type, B
chr3_-_27410847 0.090 ENST00000429845.2
ENST00000341435.5
ENST00000435750.1
NEK10


NIMA-related kinase 10


chr15_+_82555125 0.090 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
FAM154B



family with sequence similarity 154, member B



chr11_-_8615687 0.090 ENST00000534493.1
ENST00000422559.2
STK33

serine/threonine kinase 33

chr9_-_4299874 0.088 ENST00000381971.3
ENST00000477901.1
GLIS3

GLIS family zinc finger 3

chr8_-_68658578 0.088 ENST00000518549.1
ENST00000297770.4
ENST00000297769.4
CPA6


carboxypeptidase A6


chr1_+_209757051 0.087 ENST00000009105.1
ENST00000423146.1
ENST00000361322.2
CAMK1G


calcium/calmodulin-dependent protein kinase IG


chr6_+_74072375 0.087 ENST00000370367.3
KHDC3L
KH domain containing 3-like, subcortical maternal complex member
chr15_+_82555169 0.087 ENST00000565432.1
ENST00000427381.2
FAM154B

family with sequence similarity 154, member B

chr4_+_71384257 0.086 ENST00000339336.4
AMTN
amelotin
chr17_-_39211463 0.086 ENST00000542910.1
ENST00000398477.1
KRTAP2-2

keratin associated protein 2-2

chr10_+_47746929 0.084 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2



AL603965.1
annexin A8-like 2



Protein LOC100996760
chr10_-_75401500 0.084 ENST00000359322.4
MYOZ1
myozenin 1
chr19_-_3028354 0.083 ENST00000586422.1
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr21_-_43771226 0.083 ENST00000291526.4
TFF2
trefoil factor 2
chr16_+_66400533 0.082 ENST00000341529.3
CDH5
cadherin 5, type 2 (vascular endothelium)
chr1_+_120049809 0.079 ENST00000531340.1
HSD3B1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
chr1_+_1370903 0.079 ENST00000338660.5
ENST00000404702.3
ENST00000476993.1
ENST00000471398.1
VWA1



von Willebrand factor A domain containing 1



chr3_-_122233723 0.079 ENST00000493510.1
ENST00000344337.6
ENST00000476916.1
ENST00000465882.1
KPNA1



karyopherin alpha 1 (importin alpha 5)



chr15_-_72563585 0.079 ENST00000287196.9
ENST00000260376.7
PARP6

poly (ADP-ribose) polymerase family, member 6

chr10_-_50396357 0.079 ENST00000453436.1
ENST00000474718.1
C10orf128

chromosome 10 open reading frame 128

chr16_-_88851618 0.078 ENST00000301015.9
PIEZO1
piezo-type mechanosensitive ion channel component 1
chr12_-_120763739 0.078 ENST00000549767.1
PLA2G1B
phospholipase A2, group IB (pancreas)
chr13_+_60971427 0.078 ENST00000535286.1
ENST00000377881.2
TDRD3

tudor domain containing 3

chr15_-_82555000 0.077 ENST00000557844.1
ENST00000359445.3
ENST00000268206.7
EFTUD1


elongation factor Tu GTP binding domain containing 1


chr19_-_11688447 0.077 ENST00000590420.1
ACP5
acid phosphatase 5, tartrate resistant
chr1_-_151762900 0.076 ENST00000440583.2
TDRKH
tudor and KH domain containing
chr13_-_50265570 0.076 ENST00000378270.5
ENST00000378284.2
ENST00000378272.5
ENST00000378268.1
ENST00000242827.6
ENST00000378282.5
EBPL





emopamil binding protein-like





chr7_-_84121858 0.075 ENST00000448879.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr5_-_135290705 0.074 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr2_-_190044480 0.074 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr12_-_121972556 0.074 ENST00000545022.1
KDM2B
lysine (K)-specific demethylase 2B
chr8_-_10512569 0.074 ENST00000382483.3
RP1L1
retinitis pigmentosa 1-like 1
chr16_-_67965756 0.072 ENST00000571044.1
ENST00000571605.1
CTRL

chymotrypsin-like

chr16_+_53483983 0.071 ENST00000544545.1
RBL2
retinoblastoma-like 2 (p130)
chr10_-_50396407 0.071 ENST00000374153.2
ENST00000374151.3
C10orf128

chromosome 10 open reading frame 128

chr1_-_151762943 0.071 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
TDRKH




tudor and KH domain containing




chr12_+_19358228 0.070 ENST00000424268.1
ENST00000543806.1
PLEKHA5

pleckstrin homology domain containing, family A member 5

chr12_-_96389702 0.070 ENST00000552509.1
HAL
histidine ammonia-lyase
chr20_+_2795609 0.070 ENST00000554164.1
ENST00000380593.4
TMEM239
TMEM239
transmembrane protein 239
CDNA FLJ26142 fis, clone TST04526; Transmembrane protein 239; Uncharacterized protein
chr10_+_48255253 0.070 ENST00000357718.4
ENST00000344416.5
ENST00000456111.2
ENST00000374258.3
ANXA8


AL591684.1
annexin A8


Protein LOC100996760
chr14_+_65171099 0.070 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr14_+_65171315 0.070 ENST00000394691.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr15_-_40401062 0.069 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
BMF



Bcl2 modifying factor



chr1_+_45478568 0.069 ENST00000428106.1
UROD
uroporphyrinogen decarboxylase
chr6_+_133135580 0.068 ENST00000230050.3
RPS12
ribosomal protein S12
chr11_-_128712362 0.068 ENST00000392664.2
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr6_+_133562472 0.067 ENST00000430974.2
ENST00000367895.5
ENST00000355167.3
ENST00000355286.6
EYA4



eyes absent homolog 4 (Drosophila)



chr1_-_1850697 0.067 ENST00000378598.4
ENST00000416272.1
ENST00000310991.3
TMEM52


transmembrane protein 52


chr10_-_121632266 0.067 ENST00000360003.3
ENST00000369077.3
MCMBP

minichromosome maintenance complex binding protein

chr7_+_155090271 0.066 ENST00000476756.1
INSIG1
insulin induced gene 1
chr2_-_220436248 0.066 ENST00000265318.4
OBSL1
obscurin-like 1
chr15_+_74218787 0.066 ENST00000261921.7
LOXL1
lysyl oxidase-like 1
chr12_-_95611149 0.065 ENST00000549499.1
ENST00000343958.4
ENST00000546711.1
FGD6


FYVE, RhoGEF and PH domain containing 6


chr13_-_21348050 0.065 ENST00000382754.4
N6AMT2
N-6 adenine-specific DNA methyltransferase 2 (putative)
chr13_-_21348066 0.065 ENST00000382758.1
N6AMT2
N-6 adenine-specific DNA methyltransferase 2 (putative)
chr2_-_45166338 0.065 ENST00000437916.2
RP11-89K21.1
RP11-89K21.1
chr7_+_18329712 0.065 ENST00000433709.2
HDAC9
histone deacetylase 9
chr12_+_19358192 0.063 ENST00000538305.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr19_+_55999916 0.063 ENST00000587166.1
ENST00000389623.6
SSC5D

scavenger receptor cysteine rich domain containing (5 domains)

chrX_+_153627231 0.062 ENST00000406022.2
RPL10
ribosomal protein L10
chr1_+_151030234 0.062 ENST00000368921.3
MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_196857144 0.061 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
CFHR4


complement factor H-related 4


chr3_-_129279894 0.061 ENST00000506979.1
PLXND1
plexin D1
chr2_-_220435963 0.061 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
OBSL1




obscurin-like 1




chr1_+_186265399 0.061 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
PRG4






proteoglycan 4






chr17_+_42925270 0.060 ENST00000253410.2
ENST00000587021.1
HIGD1B

HIG1 hypoxia inducible domain family, member 1B

chr2_-_74555350 0.060 ENST00000444570.1
SLC4A5
solute carrier family 4 (sodium bicarbonate cotransporter), member 5
chr15_+_81475047 0.060 ENST00000559388.1
IL16
interleukin 16
chr11_+_98891797 0.059 ENST00000527185.1
ENST00000528682.1
ENST00000524871.1
CNTN5


contactin 5


chr3_+_30647994 0.059 ENST00000295754.5
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr21_-_19775973 0.059 ENST00000284885.3
TMPRSS15
transmembrane protease, serine 15
chr12_+_109569155 0.058 ENST00000539864.1
ACACB
acetyl-CoA carboxylase beta
chr1_+_93297622 0.058 ENST00000315741.5
RPL5
ribosomal protein L5
chr4_+_156680153 0.058 ENST00000502959.1
ENST00000505764.1
ENST00000507146.1
ENST00000264424.8
ENST00000503520.1
GUCY1B3




guanylate cyclase 1, soluble, beta 3




chr1_-_31230650 0.057 ENST00000294507.3
LAPTM5
lysosomal protein transmembrane 5
chr2_-_63815860 0.057 ENST00000272321.7
ENST00000431065.1
WDPCP

WD repeat containing planar cell polarity effector

chr10_-_123687497 0.057 ENST00000369040.3
ENST00000224652.6
ENST00000369043.3
ATE1


arginyltransferase 1


chr6_+_116692102 0.056 ENST00000359564.2
DSE
dermatan sulfate epimerase
chr10_-_118031778 0.056 ENST00000369236.1
GFRA1
GDNF family receptor alpha 1
chr3_-_48481518 0.056 ENST00000412398.2
ENST00000395696.1
CCDC51

coiled-coil domain containing 51

chr3_-_113415441 0.056 ENST00000491165.1
ENST00000316407.4
KIAA2018

KIAA2018

chr6_-_41006928 0.056 ENST00000244565.3
UNC5CL
unc-5 homolog C (C. elegans)-like
chr15_-_78592053 0.056 ENST00000267973.2
WDR61
WD repeat domain 61
chr9_+_72873837 0.056 ENST00000361138.5
SMC5
structural maintenance of chromosomes 5
chr10_-_123687399 0.056 ENST00000543447.1
ATE1
arginyltransferase 1
chr3_-_51994694 0.055 ENST00000395014.2
PCBP4
poly(rC) binding protein 4
chr8_-_55014415 0.055 ENST00000522007.1
ENST00000521898.1
ENST00000518546.1
ENST00000316963.3
LYPLA1



lysophospholipase I



chr15_-_78591912 0.055 ENST00000560569.1
ENST00000558459.1
ENST00000558311.1
WDR61


WD repeat domain 61


chr17_+_7452442 0.055 ENST00000557233.1
TNFSF12
tumor necrosis factor (ligand) superfamily, member 12
chr12_-_122240792 0.054 ENST00000541657.1
ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
RHOF
AC084018.1





ras homolog family member F (in filopodia)
AC084018.1





chr10_-_120938303 0.054 ENST00000356951.3
ENST00000298510.2
PRDX3

peroxiredoxin 3

chr17_+_7211280 0.054 ENST00000419711.2
ENST00000571955.1
ENST00000573714.1
EIF5A


eukaryotic translation initiation factor 5A


chr10_-_4720333 0.054 ENST00000430998.2
LINC00704
long intergenic non-protein coding RNA 704
chr10_-_60027642 0.054 ENST00000373935.3
IPMK
inositol polyphosphate multikinase
chr1_+_248100459 0.053 ENST00000366478.2
OR2L13
olfactory receptor, family 2, subfamily L, member 13
chr15_+_75080883 0.053 ENST00000567571.1
CSK
c-src tyrosine kinase
chr1_-_74663825 0.053 ENST00000370911.3
ENST00000370909.2
ENST00000354431.4
LRRIQ3


leucine-rich repeats and IQ motif containing 3


chr17_+_7452336 0.053 ENST00000293826.4
TNFSF12-TNFSF13
TNFSF12-TNFSF13 readthrough
chr10_-_123687431 0.053 ENST00000423243.1
ATE1
arginyltransferase 1
chr3_+_44916098 0.052 ENST00000296125.4
TGM4
transglutaminase 4
chr12_+_54519842 0.052 ENST00000508564.1
RP11-834C11.4
RP11-834C11.4
chr19_-_46146946 0.052 ENST00000536630.1
EML2
echinoderm microtubule associated protein like 2
chr12_+_65672423 0.052 ENST00000355192.3
ENST00000308259.5
ENST00000540804.1
ENST00000535664.1
ENST00000541189.1
MSRB3




methionine sulfoxide reductase B3




chr3_+_111753690 0.052 ENST00000452346.2
TMPRSS7
transmembrane protease, serine 7
chr22_-_19165917 0.052 ENST00000451283.1
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr8_-_55014336 0.052 ENST00000343231.6
LYPLA1
lysophospholipase I
chr10_+_35415851 0.052 ENST00000374726.3
CREM
cAMP responsive element modulator
chr12_-_89918982 0.051 ENST00000549504.1
POC1B
POC1 centriolar protein B
chr1_+_62417957 0.051 ENST00000307297.7
ENST00000543708.1
INADL

InaD-like (Drosophila)

chr1_+_93297582 0.051 ENST00000370321.3
RPL5
ribosomal protein L5
chr19_-_46142362 0.051 ENST00000586770.1
ENST00000591721.1
EML2

echinoderm microtubule associated protein like 2

chr1_-_25291475 0.051 ENST00000338888.3
ENST00000399916.1
RUNX3

runt-related transcription factor 3

chrX_-_38186811 0.051 ENST00000318842.7
RPGR
retinitis pigmentosa GTPase regulator
chr6_-_166075557 0.051 ENST00000539869.2
ENST00000366882.1
PDE10A

phosphodiesterase 10A


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.5 GO:0021546 rhombomere development(GO:0021546)
0.1 0.2 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.1 0.2 GO:0016598 protein arginylation(GO:0016598)
0.0 0.1 GO:2001037 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.0 0.2 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.1 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521)
0.0 0.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.1 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.1 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.2 GO:0036018 cellular response to erythropoietin(GO:0036018)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.2 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.4 GO:0008212 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.4 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.1 GO:1903979 negative regulation of microglial cell activation(GO:1903979)
0.0 0.2 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.1 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.0 0.1 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.1 GO:1900138 negative regulation of phospholipase A2 activity(GO:1900138)
0.0 0.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.1 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:0018277 protein deamination(GO:0018277)
0.0 0.0 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.1 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.1 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.1 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.0 0.1 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.0 GO:1904875 regulation of DNA ligase activity(GO:1904875)
0.0 0.2 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.0 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.0 0.1 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0 0.0 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.0 GO:0051664 nuclear pore distribution(GO:0031081) nuclear pore localization(GO:0051664)
0.0 0.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.2 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.0 GO:0060381 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.0 0.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.3 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0097453 mesaxon(GO:0097453) ensheathing process(GO:1990015)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.0 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.0 0.0 GO:0032173 septin ring(GO:0005940) septin collar(GO:0032173)
0.0 0.0 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.0 0.0 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.4 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.1 0.2 GO:0004057 arginyltransferase activity(GO:0004057)
0.1 0.5 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 0.1 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.0 0.1 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
0.0 0.1 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.1 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.0 0.1 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.2 GO:0032052 bile acid binding(GO:0032052)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.0 0.3 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.2 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.7 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts