Motif ID: TFEC_MITF_ARNTL_BHLHE41

Z-value: 0.394


Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MITFhg19_v2_chr3_+_69928256_69928385-0.941.7e-04Click!
BHLHE41hg19_v2_chr12_-_26278030_26278060-0.916.8e-04Click!
ARNTLhg19_v2_chr11_+_13299186_132994320.891.3e-03Click!
TFEChg19_v2_chr7_-_115670804_115670867-0.881.6e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of TFEC_MITF_ARNTL_BHLHE41

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_79307096 0.670 ENST00000376717.2
ENST00000223609.6
ENST00000443509.2
PRUNE2


prune homolog 2 (Drosophila)


chr13_-_46756351 0.566 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr6_+_151646800 0.559 ENST00000354675.6
AKAP12
A kinase (PRKA) anchor protein 12
chr12_+_54378923 0.520 ENST00000303460.4
HOXC10
homeobox C10
chr8_-_82395461 0.513 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr15_-_72668185 0.477 ENST00000457859.2
ENST00000566304.1
ENST00000567159.1
ENST00000429918.2
HEXA



hexosaminidase A (alpha polypeptide)



chr15_-_72668805 0.413 ENST00000268097.5
HEXA
hexosaminidase A (alpha polypeptide)
chr10_-_14050522 0.407 ENST00000342409.2
FRMD4A
FERM domain containing 4A
chr17_-_7137857 0.395 ENST00000005340.5
DVL2
dishevelled segment polarity protein 2
chr17_-_47841485 0.382 ENST00000506156.1
ENST00000240364.2
FAM117A

family with sequence similarity 117, member A

chr17_-_7137582 0.371 ENST00000575756.1
ENST00000575458.1
DVL2

dishevelled segment polarity protein 2

chr12_+_54378849 0.371 ENST00000515593.1
HOXC10
homeobox C10
chr12_+_54332535 0.368 ENST00000243056.3
HOXC13
homeobox C13
chr3_+_5020801 0.365 ENST00000256495.3
BHLHE40
basic helix-loop-helix family, member e40
chr12_-_122750957 0.344 ENST00000451053.2
VPS33A
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr13_+_113951607 0.344 ENST00000397181.3
LAMP1
lysosomal-associated membrane protein 1
chr13_+_113951532 0.342 ENST00000332556.4
LAMP1
lysosomal-associated membrane protein 1
chr19_+_10765003 0.341 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
ILF3


interleukin enhancer binding factor 3, 90kDa


chr1_+_76540386 0.327 ENST00000328299.3
ST6GALNAC3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr18_+_9136758 0.322 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ANKRD12


ankyrin repeat domain 12


chr6_+_87865262 0.315 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292



zinc finger protein 292



chr17_-_46688334 0.310 ENST00000239165.7
HOXB7
homeobox B7
chr17_-_46671323 0.310 ENST00000239151.5
HOXB5
homeobox B5
chr22_-_39637135 0.296 ENST00000440375.1
PDGFB
platelet-derived growth factor beta polypeptide
chr12_+_93964746 0.290 ENST00000536696.2
SOCS2
suppressor of cytokine signaling 2
chr12_-_114211474 0.285 ENST00000550905.1
ENST00000547963.1
RP11-438N16.1

RP11-438N16.1

chr13_-_95131923 0.282 ENST00000377028.5
ENST00000446125.1
DCT

dopachrome tautomerase

chr20_-_44519839 0.279 ENST00000372518.4
NEURL2
neuralized E3 ubiquitin protein ligase 2
chr12_-_122751002 0.276 ENST00000267199.4
VPS33A
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr6_-_84937314 0.276 ENST00000257766.4
ENST00000403245.3
KIAA1009

KIAA1009

chr12_+_54426637 0.267 ENST00000312492.2
HOXC5
homeobox C5
chr22_-_39636914 0.262 ENST00000381551.4
PDGFB
platelet-derived growth factor beta polypeptide
chr8_+_85095769 0.259 ENST00000518566.1
RALYL
RALY RNA binding protein-like
chr12_-_114211444 0.255 ENST00000510694.2
ENST00000550223.1
RP11-438N16.1

RP11-438N16.1

chr1_+_203097407 0.254 ENST00000367235.1
ADORA1
adenosine A1 receptor
chr6_+_151561506 0.250 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr3_-_112280709 0.247 ENST00000402314.2
ENST00000283290.5
ENST00000492886.1
ATG3


autophagy related 3


chr1_-_42921915 0.247 ENST00000372565.3
ENST00000433602.2
ZMYND12

zinc finger, MYND-type containing 12

chr6_+_151561085 0.242 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr12_+_56109926 0.242 ENST00000547076.1
BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chrX_+_151867214 0.241 ENST00000329342.5
ENST00000412733.1
ENST00000457643.1
MAGEA6


melanoma antigen family A, 6


chr11_+_7534999 0.237 ENST00000528947.1
ENST00000299492.4
PPFIBP2

PTPRF interacting protein, binding protein 2 (liprin beta 2)

chr15_-_40213080 0.233 ENST00000561100.1
GPR176
G protein-coupled receptor 176
chr3_+_134204551 0.232 ENST00000332047.5
ENST00000354446.3
CEP63

centrosomal protein 63kDa

chr6_+_138188378 0.232 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr12_-_58146048 0.227 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
CDK4




cyclin-dependent kinase 4




chr6_+_138188551 0.227 ENST00000237289.4
ENST00000433680.1
TNFAIP3

tumor necrosis factor, alpha-induced protein 3

chr6_+_13182751 0.224 ENST00000415087.1
PHACTR1
phosphatase and actin regulator 1
chr12_-_111358372 0.219 ENST00000548438.1
ENST00000228841.8
MYL2

myosin, light chain 2, regulatory, cardiac, slow

chr12_+_56110247 0.216 ENST00000551926.1
BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr12_-_58146128 0.215 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
CDK4


cyclin-dependent kinase 4


chr8_+_85095497 0.214 ENST00000522455.1
ENST00000521695.1
RALYL

RALY RNA binding protein-like

chr1_-_241520525 0.212 ENST00000366565.1
RGS7
regulator of G-protein signaling 7
chr19_+_50031547 0.211 ENST00000597801.1
RCN3
reticulocalbin 3, EF-hand calcium binding domain
chr6_-_134861089 0.206 ENST00000606039.1
RP11-557H15.4
RP11-557H15.4
chr3_+_134204881 0.205 ENST00000511574.1
ENST00000337090.3
ENST00000383229.3
CEP63


centrosomal protein 63kDa


chr3_+_134205000 0.204 ENST00000512894.1
ENST00000513612.2
ENST00000606977.1
CEP63


centrosomal protein 63kDa


chr3_-_113465065 0.201 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50



N(alpha)-acetyltransferase 50, NatE catalytic subunit



chr1_+_221051699 0.195 ENST00000366903.6
HLX
H2.0-like homeobox
chr8_+_126103921 0.193 ENST00000523741.1
NSMCE2
non-SMC element 2, MMS21 homolog (S. cerevisiae)
chr15_-_79383102 0.193 ENST00000558480.2
ENST00000419573.3
RASGRF1

Ras protein-specific guanine nucleotide-releasing factor 1

chr7_-_27196267 0.191 ENST00000242159.3
HOXA7
homeobox A7
chr8_-_126103948 0.182 ENST00000523297.1
KIAA0196
KIAA0196
chr12_+_56109810 0.181 ENST00000257899.2
ENST00000548925.1
ENST00000549147.1
ENST00000550412.1
BLOC1S1


RP11-644F5.10
biogenesis of lysosomal organelles complex-1, subunit 1


Uncharacterized protein
chr3_+_82035289 0.181 ENST00000470263.1
ENST00000494340.1
RP11-260O18.1

RP11-260O18.1

chr8_+_126104076 0.172 ENST00000517532.1
ENST00000287437.3
ENST00000518013.1
ENST00000522563.1
NSMCE2



non-SMC element 2, MMS21 homolog (S. cerevisiae)



chr17_-_32906388 0.166 ENST00000357754.1
C17orf102
chromosome 17 open reading frame 102
chr16_+_29127282 0.165 ENST00000562902.1
RP11-426C22.5
RP11-426C22.5
chr14_-_21852119 0.163 ENST00000555943.1
SUPT16H
suppressor of Ty 16 homolog (S. cerevisiae)
chr17_+_1627834 0.163 ENST00000419248.1
ENST00000418841.1
WDR81

WD repeat domain 81

chr4_-_113627966 0.162 ENST00000505632.1
RP11-148B6.2
RP11-148B6.2
chr4_+_128651530 0.162 ENST00000281154.4
SLC25A31
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr11_+_33037401 0.160 ENST00000241051.3
DEPDC7
DEP domain containing 7
chr3_-_20227619 0.157 ENST00000425061.1
ENST00000443724.1
ENST00000421451.1
ENST00000452020.1
ENST00000417364.1
ENST00000306698.2
ENST00000419233.2
ENST00000263753.4
ENST00000383774.1
ENST00000437051.1
ENST00000412868.1
ENST00000429446.3
ENST00000442720.1
SGOL1












shugoshin-like 1 (S. pombe)












chr19_-_49137762 0.157 ENST00000593500.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr3_-_20227720 0.155 ENST00000412997.1
SGOL1
shugoshin-like 1 (S. pombe)
chr17_-_46667594 0.155 ENST00000476342.1
ENST00000460160.1
ENST00000472863.1
HOXB3


homeobox B3


chr16_-_30134524 0.154 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
MAPK3




mitogen-activated protein kinase 3




chr6_+_138188351 0.153 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr17_-_46667628 0.153 ENST00000498678.1
HOXB3
homeobox B3
chr17_+_78075361 0.151 ENST00000577106.1
ENST00000390015.3
GAA

glucosidase, alpha; acid

chr1_+_45477819 0.151 ENST00000246337.4
UROD
uroporphyrinogen decarboxylase
chr1_-_241520385 0.151 ENST00000366564.1
RGS7
regulator of G-protein signaling 7
chr8_-_126104055 0.151 ENST00000318410.7
KIAA0196
KIAA0196
chr16_+_2570431 0.149 ENST00000563556.1
AMDHD2
amidohydrolase domain containing 2
chr11_-_85779971 0.148 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr8_-_126103969 0.146 ENST00000517845.1
KIAA0196
KIAA0196
chr11_+_67159416 0.146 ENST00000307980.2
ENST00000544620.1
RAD9A

RAD9 homolog A (S. pombe)

chr16_-_67517716 0.145 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr13_+_49684445 0.142 ENST00000398316.3
FNDC3A
fibronectin type III domain containing 3A
chr5_+_156712372 0.142 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr1_+_45477901 0.140 ENST00000434478.1
UROD
uroporphyrinogen decarboxylase
chr17_+_78075498 0.140 ENST00000302262.3
GAA
glucosidase, alpha; acid
chr7_-_155089251 0.140 ENST00000609974.1
AC144652.1
AC144652.1
chr17_+_78075324 0.140 ENST00000570803.1
GAA
glucosidase, alpha; acid
chr10_-_99258135 0.138 ENST00000327238.10
ENST00000327277.7
ENST00000355839.6
ENST00000437002.1
ENST00000422685.1
MMS19




MMS19 nucleotide excision repair homolog (S. cerevisiae)




chr16_-_30134441 0.138 ENST00000395200.1
MAPK3
mitogen-activated protein kinase 3
chr7_+_155090271 0.138 ENST00000476756.1
INSIG1
insulin induced gene 1
chr10_+_99258625 0.136 ENST00000370664.3
UBTD1
ubiquitin domain containing 1
chr9_-_140444814 0.136 ENST00000277531.4
PNPLA7
patatin-like phospholipase domain containing 7
chr17_+_7344057 0.135 ENST00000575398.1
ENST00000575082.1
FGF11

fibroblast growth factor 11

chr19_+_32836499 0.133 ENST00000311921.4
ENST00000544431.1
ENST00000355898.5
ZNF507


zinc finger protein 507


chr14_-_20923195 0.132 ENST00000206542.4
OSGEP
O-sialoglycoprotein endopeptidase
chr12_-_121972556 0.132 ENST00000545022.1
KDM2B
lysine (K)-specific demethylase 2B
chr7_-_99774945 0.131 ENST00000292377.2
GPC2
glypican 2
chr19_+_10764937 0.131 ENST00000449870.1
ENST00000318511.3
ENST00000420083.1
ILF3


interleukin enhancer binding factor 3, 90kDa


chr6_-_109703663 0.130 ENST00000368961.5
CD164
CD164 molecule, sialomucin
chr15_+_75628419 0.130 ENST00000567377.1
ENST00000562789.1
ENST00000568301.1
COMMD4


COMM domain containing 4


chr19_+_45504688 0.129 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB


v-rel avian reticuloendotheliosis viral oncogene homolog B


chr19_-_11688447 0.128 ENST00000590420.1
ACP5
acid phosphatase 5, tartrate resistant
chr9_-_140444867 0.128 ENST00000406427.1
PNPLA7
patatin-like phospholipase domain containing 7
chr3_+_133293278 0.127 ENST00000508481.1
ENST00000420115.2
ENST00000504867.1
ENST00000507408.1
ENST00000511392.1
ENST00000515421.1
CDV3





CDV3 homolog (mouse)





chr12_+_56110315 0.127 ENST00000548556.1
BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr11_+_7559485 0.125 ENST00000527790.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr20_+_61273797 0.124 ENST00000217159.1
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr15_+_75628232 0.124 ENST00000267935.8
ENST00000567195.1
COMMD4

COMM domain containing 4

chr6_-_138866823 0.124 ENST00000342260.5
NHSL1
NHS-like 1
chr3_+_158519654 0.123 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
MFSD1


major facilitator superfamily domain containing 1


chr9_-_99801925 0.122 ENST00000538255.1
CTSV
cathepsin V
chr22_-_50700140 0.122 ENST00000215659.8
MAPK12
mitogen-activated protein kinase 12
chr19_+_10812108 0.122 ENST00000250237.5
ENST00000592254.1
QTRT1

queuine tRNA-ribosyltransferase 1

chr11_-_85780086 0.122 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
PICALM


phosphatidylinositol binding clathrin assembly protein


chr17_-_42200996 0.121 ENST00000587135.1
ENST00000225983.6
ENST00000393622.2
ENST00000588703.1
HDAC5



histone deacetylase 5



chr6_-_151773232 0.121 ENST00000444024.1
ENST00000367303.4
RMND1

required for meiotic nuclear division 1 homolog (S. cerevisiae)

chr15_+_82555125 0.119 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
FAM154B



family with sequence similarity 154, member B



chr9_-_126030817 0.118 ENST00000348403.5
ENST00000447404.2
ENST00000360998.3
STRBP


spermatid perinuclear RNA binding protein


chr3_-_122512619 0.118 ENST00000383659.1
ENST00000306103.2
HSPBAP1

HSPB (heat shock 27kDa) associated protein 1

chr3_+_113465866 0.117 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A



ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A



chr15_+_91260552 0.117 ENST00000355112.3
ENST00000560509.1
BLM

Bloom syndrome, RecQ helicase-like

chr15_+_75628394 0.116 ENST00000564815.1
ENST00000338995.6
COMMD4

COMM domain containing 4

chr17_+_79935464 0.116 ENST00000581647.1
ENST00000580534.1
ENST00000579684.1
ASPSCR1


alveolar soft part sarcoma chromosome region, candidate 1


chr17_+_79935418 0.115 ENST00000306729.7
ENST00000306739.4
ASPSCR1

alveolar soft part sarcoma chromosome region, candidate 1

chrX_-_118699325 0.115 ENST00000320339.4
ENST00000371594.4
ENST00000536133.1
CXorf56


chromosome X open reading frame 56


chr17_-_42200958 0.115 ENST00000336057.5
HDAC5
histone deacetylase 5
chrX_-_9734004 0.115 ENST00000467482.1
ENST00000380929.2
GPR143

G protein-coupled receptor 143

chr19_-_49137790 0.113 ENST00000599385.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chrX_+_135229731 0.112 ENST00000420362.1
FHL1
four and a half LIM domains 1
chr3_+_112280857 0.112 ENST00000492406.1
ENST00000468642.1
SLC35A5

solute carrier family 35, member A5

chr14_+_20923350 0.111 ENST00000555414.1
ENST00000216714.3
ENST00000553681.1
ENST00000557344.1
ENST00000398030.4
ENST00000557181.1
ENST00000555839.1
ENST00000553368.1
ENST00000556054.1
ENST00000557054.1
ENST00000557592.1
ENST00000557150.1
APEX1











APEX nuclease (multifunctional DNA repair enzyme) 1











chr6_+_160390102 0.111 ENST00000356956.1
IGF2R
insulin-like growth factor 2 receptor
chr21_-_16374688 0.111 ENST00000411932.1
NRIP1
nuclear receptor interacting protein 1
chr1_-_166944652 0.111 ENST00000528703.1
ENST00000525740.1
ENST00000529387.1
ENST00000469934.2
ENST00000529071.1
ENST00000526687.1
ILDR2





immunoglobulin-like domain containing receptor 2





chr10_+_112327425 0.110 ENST00000361804.4
SMC3
structural maintenance of chromosomes 3
chr1_-_150738261 0.108 ENST00000448301.2
ENST00000368985.3
CTSS

cathepsin S

chr12_+_93964158 0.107 ENST00000549206.1
SOCS2
suppressor of cytokine signaling 2
chr9_-_117568365 0.106 ENST00000374045.4
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr12_-_109027643 0.105 ENST00000388962.3
ENST00000550948.1
SELPLG

selectin P ligand

chr13_-_50367057 0.105 ENST00000261667.3
KPNA3
karyopherin alpha 3 (importin alpha 4)
chr2_+_75061108 0.105 ENST00000290573.2
HK2
hexokinase 2
chr11_-_61560053 0.104 ENST00000537328.1
TMEM258
transmembrane protein 258
chr3_-_17783990 0.104 ENST00000429383.4
ENST00000446863.1
ENST00000414349.1
ENST00000428355.1
ENST00000425944.1
ENST00000445294.1
ENST00000444471.1
ENST00000415814.2
TBC1D5







TBC1 domain family, member 5







chr7_+_36429409 0.104 ENST00000265748.2
ANLN
anillin, actin binding protein
chr17_-_79791118 0.104 ENST00000576431.1
ENST00000575061.1
ENST00000455127.2
ENST00000572645.1
ENST00000538396.1
ENST00000573478.1
FAM195B





family with sequence similarity 195, member B





chr15_-_82555000 0.103 ENST00000557844.1
ENST00000359445.3
ENST00000268206.7
EFTUD1


elongation factor Tu GTP binding domain containing 1


chr16_+_88636789 0.103 ENST00000301011.5
ENST00000452588.2
ZC3H18

zinc finger CCCH-type containing 18

chr13_+_43597269 0.103 ENST00000379221.2
DNAJC15
DnaJ (Hsp40) homolog, subfamily C, member 15
chr22_-_50699972 0.101 ENST00000395778.3
MAPK12
mitogen-activated protein kinase 12
chr16_+_11762270 0.101 ENST00000329565.5
SNN
stannin
chr21_-_32119551 0.100 ENST00000333892.2
KRTAP21-2
keratin associated protein 21-2
chr17_+_12859080 0.099 ENST00000583608.1
ARHGAP44
Rho GTPase activating protein 44
chr7_+_36429424 0.098 ENST00000396068.2
ANLN
anillin, actin binding protein
chr20_+_31407692 0.098 ENST00000375571.5
MAPRE1
microtubule-associated protein, RP/EB family, member 1
chr1_-_23520755 0.097 ENST00000314113.3
HTR1D
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr20_-_30458019 0.097 ENST00000486996.1
ENST00000398084.2
DUSP15

dual specificity phosphatase 15

chr3_-_57678772 0.096 ENST00000311128.5
DENND6A
DENN/MADD domain containing 6A
chr2_+_232575168 0.096 ENST00000440384.1
PTMA
prothymosin, alpha
chr1_-_166944561 0.095 ENST00000271417.3
ILDR2
immunoglobulin-like domain containing receptor 2
chr1_+_40627038 0.094 ENST00000372771.4
RLF
rearranged L-myc fusion
chr13_-_79233314 0.094 ENST00000282003.6
RNF219
ring finger protein 219
chr9_+_133454943 0.093 ENST00000319725.9
FUBP3
far upstream element (FUSE) binding protein 3
chr6_-_109703600 0.093 ENST00000512821.1
CD164
CD164 molecule, sialomucin
chr7_+_100464760 0.093 ENST00000200457.4
TRIP6
thyroid hormone receptor interactor 6
chr1_+_42922173 0.093 ENST00000455780.1
ENST00000372560.3
ENST00000372561.3
ENST00000372556.3
PPCS



phosphopantothenoylcysteine synthetase



chr5_+_34656529 0.093 ENST00000513974.1
ENST00000512629.1
RAI14

retinoic acid induced 14

chr21_-_45196326 0.093 ENST00000291568.5
CSTB
cystatin B (stefin B)
chr14_-_20929624 0.093 ENST00000398020.4
ENST00000250489.4
TMEM55B

transmembrane protein 55B

chr9_-_34048873 0.092 ENST00000449054.1
ENST00000379239.4
ENST00000539807.1
ENST00000379238.1
ENST00000418786.2
ENST00000360802.1
ENST00000412543.1
UBAP2






ubiquitin associated protein 2






chr11_+_125774258 0.091 ENST00000263576.6
DDX25
DEAD (Asp-Glu-Ala-Asp) box helicase 25
chr20_+_37590942 0.091 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DHX35


DEAH (Asp-Glu-Ala-His) box polypeptide 35


chr1_+_42921761 0.091 ENST00000372562.1
PPCS
phosphopantothenoylcysteine synthetase
chr12_+_28343365 0.091 ENST00000545336.1
CCDC91
coiled-coil domain containing 91
chrX_+_134124968 0.091 ENST00000330288.4
SMIM10
small integral membrane protein 10
chr10_+_46222648 0.091 ENST00000336378.4
ENST00000540872.1
ENST00000537517.1
ENST00000374362.2
ENST00000359860.4
ENST00000420848.1
FAM21C





family with sequence similarity 21, member C





chr7_+_116593433 0.091 ENST00000323984.3
ENST00000393449.1
ST7

suppression of tumorigenicity 7

chr7_+_99070527 0.090 ENST00000379724.3
ZNF789
zinc finger protein 789
chr16_+_2570340 0.090 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
AMDHD2





amidohydrolase domain containing 2





chr17_-_18266660 0.090 ENST00000582653.1
ENST00000352886.6
SHMT1

serine hydroxymethyltransferase 1 (soluble)

chr19_-_11688500 0.090 ENST00000433365.2
ACP5
acid phosphatase 5, tartrate resistant
chr2_-_182545603 0.089 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr1_+_202995611 0.088 ENST00000367240.2
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr7_+_116593568 0.088 ENST00000446490.1
ST7
suppression of tumorigenicity 7
chr3_+_51976338 0.088 ENST00000417220.2
ENST00000431474.1
ENST00000398755.3
PARP3


poly (ADP-ribose) polymerase family, member 3


chr3_+_133292851 0.087 ENST00000503932.1
CDV3
CDV3 homolog (mouse)
chr11_+_7595136 0.087 ENST00000529575.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr5_+_34656569 0.087 ENST00000428746.2
RAI14
retinoic acid induced 14
chr5_+_34656331 0.087 ENST00000265109.3
RAI14
retinoic acid induced 14
chr5_+_34656450 0.086 ENST00000514527.1
RAI14
retinoic acid induced 14
chr16_+_24621546 0.086 ENST00000566108.1
CTD-2540M10.1
CTD-2540M10.1
chr7_+_155089486 0.086 ENST00000340368.4
ENST00000344756.4
ENST00000425172.1
ENST00000342407.5
INSIG1



insulin induced gene 1



chr16_+_88923494 0.086 ENST00000567895.1
ENST00000301021.3
ENST00000565504.1
ENST00000567312.1
ENST00000568583.1
ENST00000561840.1
TRAPPC2L





trafficking protein particle complex 2-like






Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0070429 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.2 0.8 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 0.4 GO:0043181 vacuolar sequestering(GO:0043181)
0.1 0.6 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.7 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.4 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.1 0.3 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.1 1.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.4 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.1 0.6 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.2 GO:0031106 septin ring assembly(GO:0000921) septin ring organization(GO:0031106)
0.1 0.8 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.2 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.1 0.2 GO:1904481 response to tetrahydrofolate(GO:1904481) cellular response to tetrahydrofolate(GO:1904482)
0.0 0.3 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.3 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.3 GO:0021546 rhombomere development(GO:0021546)
0.0 0.1 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.0 0.7 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.1 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0 0.2 GO:0090299 regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.0 0.1 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.7 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.8 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0001207 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.0 0.1 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.5 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.1 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.1 GO:1900073 regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.5 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.1 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.0 0.1 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.2 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.2 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.1 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.1 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.2 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.3 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.3 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.0 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.0 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.1 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.1 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
0.0 0.0 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.0 0.1 GO:0015883 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.0 0.2 GO:1990834 response to odorant(GO:1990834)
0.0 0.6 GO:0030220 platelet formation(GO:0030220)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0036369 transcription factor catabolic process(GO:0036369)
0.0 0.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.0 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.0 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.0 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.0 0.0 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.0 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.1 GO:0048278 vesicle docking(GO:0048278)
0.0 0.0 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.0 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.0 0.1 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.3 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.1 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0071105 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340) response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.0 0.0 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.2 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.1 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.1 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.0 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.0 0.1 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.0 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.0 GO:0007521 muscle cell fate determination(GO:0007521)
0.0 0.0 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.3 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.1 GO:1904448 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450)
0.0 0.1 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.0 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.0 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.0 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.0 GO:0034059 response to anoxia(GO:0034059)
0.0 0.1 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.0 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.0 GO:0072003 kidney rudiment formation(GO:0072003)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.4 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.0 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.0 0.1 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.8 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 0.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.2 GO:0035101 FACT complex(GO:0035101)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:1902737 dendritic filopodium(GO:1902737)
0.0 0.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.6 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0005960 glycine cleavage complex(GO:0005960)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0043614 multi-eIF complex(GO:0043614)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.0 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.6 GO:0031143 pseudopodium(GO:0031143)
0.0 0.0 GO:1990742 microvesicle(GO:1990742)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.0 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.0 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0002133 polycystin complex(GO:0002133)
0.0 0.1 GO:0032144 4-aminobutyrate transaminase complex(GO:0032144)
0.0 0.2 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.0 GO:0001534 radial spoke(GO:0001534)
0.0 0.1 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.9 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.3 GO:0004853 uroporphyrinogen decarboxylase activity(GO:0004853)
0.1 0.2 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.1 0.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 0.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.2 GO:0030984 kininogen binding(GO:0030984)
0.1 1.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.3 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.2 GO:0070905 serine binding(GO:0070905)
0.0 0.4 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0072544 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.0 0.1 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.0 0.2 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.0 0.0 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.0 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0031177 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315) S-acetyltransferase activity(GO:0016418) phosphopantetheine binding(GO:0031177)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.1 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.0 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.0 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.0 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0000403 Y-form DNA binding(GO:0000403) four-way junction helicase activity(GO:0009378)
0.0 0.0 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.0 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0032145 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298)
0.0 0.0 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.0 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.0 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.0 0.1 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.0 0.9 PID_WNT_CANONICAL_PATHWAY Canonical Wnt signaling pathway
0.0 0.4 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.2 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.9 REACTOME_SIGNALING_BY_HIPPO Genes involved in Signaling by Hippo
0.0 0.6 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.6 REACTOME_LYSOSOME_VESICLE_BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.3 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.1 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.1 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 0.2 REACTOME_MEIOSIS Genes involved in Meiosis