Motif ID: TFAP2B

Z-value: 0.523


Transcription factors associated with TFAP2B:

Gene SymbolEntrez IDGene Name
TFAP2B ENSG00000008196.8 TFAP2B



Activity profile for motif TFAP2B.

activity profile for motif TFAP2B


Sorted Z-values histogram for motif TFAP2B

Sorted Z-values for motif TFAP2B



Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP2B

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_83442915 0.712 ENST00000262752.2
ENST00000543399.1
RPS6KA6

ribosomal protein S6 kinase, 90kDa, polypeptide 6

chr1_-_161039647 0.670 ENST00000368013.3
ARHGAP30
Rho GTPase activating protein 30
chr1_-_161039753 0.664 ENST00000368015.1
ARHGAP30
Rho GTPase activating protein 30
chr19_-_51220176 0.658 ENST00000359082.3
ENST00000293441.1
SHANK1

SH3 and multiple ankyrin repeat domains 1

chr1_-_161039456 0.637 ENST00000368016.3
ARHGAP30
Rho GTPase activating protein 30
chr11_-_7694684 0.579 ENST00000524790.1
ENST00000299497.9
ENST00000299498.6
CYB5R2


cytochrome b5 reductase 2


chr1_-_49242553 0.540 ENST00000371833.3
BEND5
BEN domain containing 5
chr11_-_7695437 0.524 ENST00000533558.1
ENST00000527542.1
ENST00000531096.1
CYB5R2


cytochrome b5 reductase 2


chr11_-_7694974 0.478 ENST00000436351.2
CYB5R2
cytochrome b5 reductase 2
chr11_+_63974135 0.447 ENST00000544997.1
ENST00000345728.5
ENST00000279227.5
FERMT3


fermitin family member 3


chr19_-_10628117 0.436 ENST00000333430.4
S1PR5
sphingosine-1-phosphate receptor 5
chr14_+_94640633 0.389 ENST00000304338.3
PPP4R4
protein phosphatase 4, regulatory subunit 4
chr10_-_5638048 0.371 ENST00000478294.1
RP13-463N16.6
RP13-463N16.6
chr14_+_79745682 0.341 ENST00000557594.1
NRXN3
neurexin 3
chr11_+_7273181 0.339 ENST00000318881.6
SYT9
synaptotagmin IX
chr11_+_131781290 0.333 ENST00000425719.2
ENST00000374784.1
NTM

neurotrimin

chr15_-_79383102 0.333 ENST00000558480.2
ENST00000419573.3
RASGRF1

Ras protein-specific guanine nucleotide-releasing factor 1

chr1_+_153746683 0.329 ENST00000271857.2
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr19_-_10628098 0.321 ENST00000590601.1
S1PR5
sphingosine-1-phosphate receptor 5
chr2_-_73511559 0.313 ENST00000521871.1
FBXO41
F-box protein 41
chr17_+_12692774 0.305 ENST00000379672.5
ENST00000340825.3
ARHGAP44

Rho GTPase activating protein 44

chr14_+_79745746 0.303 ENST00000281127.7
NRXN3
neurexin 3
chr17_+_12693001 0.302 ENST00000262444.9
ARHGAP44
Rho GTPase activating protein 44
chr11_-_63684316 0.297 ENST00000301459.4
RCOR2
REST corepressor 2
chr14_+_79746249 0.287 ENST00000428277.2
NRXN3
neurexin 3
chr19_-_12945362 0.277 ENST00000590404.1
ENST00000592204.1
RTBDN

retbindin

chr1_+_2398876 0.255 ENST00000449969.1
PLCH2
phospholipase C, eta 2
chr6_-_32191834 0.251 ENST00000375023.3
NOTCH4
notch 4
chr22_-_39639021 0.244 ENST00000455790.1
PDGFB
platelet-derived growth factor beta polypeptide
chr22_+_45072925 0.242 ENST00000006251.7
PRR5
proline rich 5 (renal)
chr17_-_17726907 0.236 ENST00000423161.3
SREBF1
sterol regulatory element binding transcription factor 1
chr20_+_44746939 0.230 ENST00000372276.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr11_-_6677018 0.226 ENST00000299441.3
DCHS1
dachsous cadherin-related 1
chr3_+_125687987 0.225 ENST00000514116.1
ENST00000251776.4
ENST00000504401.1
ENST00000513830.1
ENST00000508088.1
ROPN1B




rhophilin associated tail protein 1B




chr20_+_44746885 0.225 ENST00000372285.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr11_-_61348576 0.224 ENST00000263846.4
SYT7
synaptotagmin VII
chr12_+_50451462 0.222 ENST00000447966.2
ASIC1
acid-sensing (proton-gated) ion channel 1
chr1_-_40782938 0.221 ENST00000372736.3
ENST00000372748.3
COL9A2

collagen, type IX, alpha 2

chr8_+_142402089 0.219 ENST00000521578.1
ENST00000520105.1
ENST00000523147.1
PTP4A3


protein tyrosine phosphatase type IVA, member 3


chr1_+_154378049 0.219 ENST00000512471.1
IL6R
interleukin 6 receptor
chr17_-_61777459 0.216 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIMD2


LIM domain containing 2


chr13_+_52158610 0.208 ENST00000298125.5
WDFY2
WD repeat and FYVE domain containing 2
chr11_-_61348292 0.189 ENST00000539008.1
ENST00000540677.1
ENST00000542836.1
ENST00000542670.1
ENST00000535826.1
ENST00000545053.1
SYT7





synaptotagmin VII





chr19_+_41107249 0.185 ENST00000396819.3
LTBP4
latent transforming growth factor beta binding protein 4
chr15_+_23810903 0.182 ENST00000564592.1
MKRN3
makorin ring finger protein 3
chr15_+_90319557 0.182 ENST00000341735.3
MESP2
mesoderm posterior 2 homolog (mouse)
chr13_+_60971427 0.181 ENST00000535286.1
ENST00000377881.2
TDRD3

tudor domain containing 3

chr1_+_221054411 0.181 ENST00000427693.1
HLX
H2.0-like homeobox
chr14_+_94640671 0.179 ENST00000328839.3
PPP4R4
protein phosphatase 4, regulatory subunit 4
chr3_+_150804676 0.177 ENST00000474524.1
ENST00000273432.4
MED12L

mediator complex subunit 12-like

chr3_-_158450475 0.177 ENST00000237696.5
RARRES1
retinoic acid receptor responder (tazarotene induced) 1
chr12_+_121078355 0.177 ENST00000316803.3
CABP1
calcium binding protein 1
chr9_+_116917807 0.174 ENST00000356083.3
COL27A1
collagen, type XXVII, alpha 1
chr7_-_25219897 0.171 ENST00000283905.3
ENST00000409280.1
ENST00000415598.1
C7orf31


chromosome 7 open reading frame 31


chr19_-_49149553 0.170 ENST00000084798.4
CA11
carbonic anhydrase XI
chr3_+_158450143 0.170 ENST00000491804.1
MFSD1
major facilitator superfamily domain containing 1
chr22_+_21987005 0.163 ENST00000607942.1
ENST00000425975.1
ENST00000292779.3
CCDC116


coiled-coil domain containing 116


chr14_+_65171315 0.161 ENST00000394691.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr11_+_8040739 0.161 ENST00000534099.1
TUB
tubby bipartite transcription factor
chr12_-_110011288 0.161 ENST00000540016.1
ENST00000266839.5
MMAB

methylmalonic aciduria (cobalamin deficiency) cblB type

chr17_+_37824217 0.159 ENST00000394246.1
PNMT
phenylethanolamine N-methyltransferase
chr1_-_155006224 0.158 ENST00000368424.3
DCST2
DC-STAMP domain containing 2
chr1_+_154377669 0.158 ENST00000368485.3
ENST00000344086.4
IL6R

interleukin 6 receptor

chr1_+_221054584 0.157 ENST00000549319.1
HLX
H2.0-like homeobox
chr15_-_74044719 0.155 ENST00000559817.1
C15orf59
chromosome 15 open reading frame 59
chr14_+_65171099 0.155 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr21_-_43786634 0.154 ENST00000291527.2
TFF1
trefoil factor 1
chr22_-_50708781 0.153 ENST00000449719.2
ENST00000330651.6
MAPK11

mitogen-activated protein kinase 11

chr5_+_156693159 0.150 ENST00000347377.6
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr3_-_48470838 0.149 ENST00000358459.4
ENST00000358536.4
PLXNB1

plexin B1

chr15_+_101420028 0.149 ENST00000557963.1
ENST00000346623.6
ALDH1A3

aldehyde dehydrogenase 1 family, member A3

chr2_+_45878790 0.149 ENST00000306156.3
PRKCE
protein kinase C, epsilon
chr1_-_42921915 0.148 ENST00000372565.3
ENST00000433602.2
ZMYND12

zinc finger, MYND-type containing 12

chr13_+_98795664 0.147 ENST00000376581.5
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr14_+_65170820 0.142 ENST00000555982.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr20_-_31172598 0.142 ENST00000201961.2
C20orf112
chromosome 20 open reading frame 112
chr7_+_120628731 0.142 ENST00000310396.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr1_-_98386543 0.142 ENST00000423006.2
ENST00000370192.3
ENST00000306031.5
DPYD


dihydropyrimidine dehydrogenase


chr11_-_417388 0.142 ENST00000332725.3
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr12_+_19282713 0.141 ENST00000299275.6
ENST00000539256.1
ENST00000538714.1
PLEKHA5


pleckstrin homology domain containing, family A member 5


chr14_-_37641618 0.141 ENST00000555449.1
SLC25A21
solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
chr22_+_42229100 0.140 ENST00000361204.4
SREBF2
sterol regulatory element binding transcription factor 2
chr12_+_49212514 0.137 ENST00000301050.2
ENST00000548279.1
ENST00000547230.1
CACNB3


calcium channel, voltage-dependent, beta 3 subunit


chr16_+_22825475 0.137 ENST00000261374.3
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr2_+_71558858 0.136 ENST00000437658.2
ENST00000355812.3
ENST00000377802.2
ENST00000264447.4
ENST00000409544.1
ENST00000455226.1
ENST00000454278.1
ENST00000417778.1
ENST00000454122.1
ZNF638








zinc finger protein 638








chr22_-_27620603 0.134 ENST00000418271.1
ENST00000444114.1
RP5-1172A22.1

RP5-1172A22.1

chr12_-_122238913 0.134 ENST00000537157.1
AC084018.1
AC084018.1
chr7_-_25219667 0.133 ENST00000444434.1
C7orf31
chromosome 7 open reading frame 31
chr20_-_56285595 0.133 ENST00000395816.3
ENST00000347215.4
PMEPA1

prostate transmembrane protein, androgen induced 1

chr20_+_60174827 0.133 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chrX_-_108868390 0.131 ENST00000372101.2
KCNE1L
KCNE1-like
chr12_+_49212261 0.131 ENST00000547818.1
ENST00000547392.1
CACNB3

calcium channel, voltage-dependent, beta 3 subunit

chr5_+_149569520 0.131 ENST00000230671.2
ENST00000524041.1
SLC6A7

solute carrier family 6 (neurotransmitter transporter), member 7

chr2_+_232575168 0.129 ENST00000440384.1
PTMA
prothymosin, alpha
chr10_+_60145155 0.128 ENST00000373895.3
TFAM
transcription factor A, mitochondrial
chr12_+_106994905 0.127 ENST00000357881.4
RFX4
regulatory factor X, 4 (influences HLA class II expression)
chr14_-_101014435 0.127 ENST00000554356.1
BEGAIN
brain-enriched guanylate kinase-associated
chr12_+_110011571 0.127 ENST00000539696.1
ENST00000228510.3
ENST00000392727.3
MVK


mevalonate kinase


chr12_+_19282643 0.126 ENST00000317589.4
ENST00000355397.3
ENST00000359180.3
ENST00000309364.4
ENST00000540972.1
ENST00000429027.2
PLEKHA5





pleckstrin homology domain containing, family A member 5





chr3_+_135684515 0.126 ENST00000264977.3
ENST00000490467.1
PPP2R3A

protein phosphatase 2, regulatory subunit B'', alpha

chr20_-_31124186 0.125 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr10_+_99079008 0.122 ENST00000371021.3
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr3_-_39195037 0.120 ENST00000273153.5
CSRNP1
cysteine-serine-rich nuclear protein 1
chr1_+_155051379 0.120 ENST00000418360.2
EFNA3
ephrin-A3
chr8_+_21906658 0.120 ENST00000523300.1
DMTN
dematin actin binding protein
chrX_+_70316005 0.120 ENST00000374259.3
FOXO4
forkhead box O4
chr22_-_31742218 0.120 ENST00000266269.5
ENST00000405309.3
ENST00000351933.4
PATZ1


POZ (BTB) and AT hook containing zinc finger 1


chr1_+_155006300 0.118 ENST00000295542.1
ENST00000392480.1
ENST00000423025.2
ENST00000368419.2
DCST1



DC-STAMP domain containing 1



chr9_+_134165195 0.115 ENST00000372261.1
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr15_+_65822756 0.115 ENST00000562901.1
ENST00000261875.5
ENST00000442729.2
ENST00000565299.1
ENST00000568793.1
PTPLAD1




protein tyrosine phosphatase-like A domain containing 1




chr13_-_76056250 0.114 ENST00000377636.3
ENST00000431480.2
ENST00000377625.2
ENST00000425511.1
TBC1D4



TBC1 domain family, member 4



chr12_-_122018346 0.114 ENST00000377069.4
KDM2B
lysine (K)-specific demethylase 2B
chr15_+_85144217 0.114 ENST00000540936.1
ENST00000448803.2
ENST00000546275.1
ENST00000546148.1
ENST00000442073.3
ENST00000334141.3
ENST00000358472.3
ENST00000502939.2
ENST00000379358.3
ENST00000327179.6
ZSCAN2









zinc finger and SCAN domain containing 2









chr9_-_33402506 0.113 ENST00000377425.4
ENST00000537089.1
ENST00000297988.1
ENST00000539936.1
ENST00000541274.1
AQP7




aquaporin 7




chr2_-_218770168 0.112 ENST00000413554.1
TNS1
tensin 1
chr10_-_104178857 0.112 ENST00000020673.5
PSD
pleckstrin and Sec7 domain containing
chr7_+_120629085 0.111 ENST00000428526.1
CPED1
cadherin-like and PC-esterase domain containing 1
chr19_-_12946215 0.109 ENST00000591512.1
ENST00000587549.1
ENST00000322912.5
RTBDN


retbindin


chr10_-_75401500 0.108 ENST00000359322.4
MYOZ1
myozenin 1
chr3_-_138048631 0.108 ENST00000484930.1
ENST00000475751.1
NME9

NME/NM23 family member 9

chr19_-_10024496 0.107 ENST00000593091.1
OLFM2
olfactomedin 2
chr1_+_201617450 0.106 ENST00000295624.6
ENST00000367297.4
ENST00000367300.3
NAV1


neuron navigator 1


chr16_-_88772761 0.106 ENST00000567844.1
ENST00000312838.4
RNF166

ring finger protein 166

chrX_+_95939711 0.106 ENST00000373049.4
ENST00000324765.8
DIAPH2

diaphanous-related formin 2

chr3_-_48471454 0.106 ENST00000296440.6
ENST00000448774.2
PLXNB1

plexin B1

chr16_+_30960375 0.105 ENST00000318663.4
ENST00000566237.1
ENST00000562699.1
ORAI3


ORAI calcium release-activated calcium modulator 3


chr3_-_123710893 0.104 ENST00000467907.1
ENST00000459660.1
ENST00000495093.1
ENST00000460743.1
ENST00000405845.3
ENST00000484329.1
ENST00000479867.1
ENST00000496145.1
ROPN1







rhophilin associated tail protein 1







chr17_-_40835076 0.103 ENST00000591765.1
CCR10
chemokine (C-C motif) receptor 10
chr16_+_88772866 0.103 ENST00000453996.2
ENST00000312060.5
ENST00000378384.3
ENST00000567949.1
ENST00000564921.1
CTU2




cytosolic thiouridylase subunit 2 homolog (S. pombe)




chr16_-_71323617 0.103 ENST00000563876.1
CMTR2
cap methyltransferase 2
chr8_-_144655141 0.103 ENST00000398882.3
MROH6
maestro heat-like repeat family member 6
chr7_+_44143925 0.102 ENST00000223357.3
AEBP1
AE binding protein 1
chr17_-_61777090 0.102 ENST00000578061.1
LIMD2
LIM domain containing 2
chr2_-_208030647 0.101 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr17_+_1627834 0.101 ENST00000419248.1
ENST00000418841.1
WDR81

WD repeat domain 81

chr3_+_149531607 0.100 ENST00000468648.1
ENST00000459632.1
RNF13

ring finger protein 13

chr1_+_65613852 0.100 ENST00000327299.7
AK4
adenylate kinase 4
chr12_-_31477072 0.099 ENST00000454658.2
FAM60A
family with sequence similarity 60, member A
chr15_+_65823092 0.099 ENST00000566074.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr6_+_99282570 0.099 ENST00000328345.5
POU3F2
POU class 3 homeobox 2
chr1_+_2036149 0.099 ENST00000482686.1
ENST00000400920.1
ENST00000486681.1
PRKCZ


protein kinase C, zeta


chr19_-_11689752 0.098 ENST00000592659.1
ENST00000592828.1
ENST00000218758.5
ENST00000412435.2
ACP5



acid phosphatase 5, tartrate resistant



chr1_+_1981890 0.098 ENST00000378567.3
ENST00000468310.1
PRKCZ

protein kinase C, zeta

chrX_+_95939638 0.098 ENST00000373061.3
ENST00000373054.4
ENST00000355827.4
DIAPH2


diaphanous-related formin 2


chr6_+_151186554 0.098 ENST00000367321.3
ENST00000367307.4
MTHFD1L

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like

chr13_-_99852916 0.097 ENST00000426037.2
ENST00000445737.2
UBAC2-AS1

UBAC2 antisense RNA 1

chr6_-_160114260 0.095 ENST00000367054.2
ENST00000367055.4
ENST00000444946.2
ENST00000452684.2
SOD2



superoxide dismutase 2, mitochondrial



chr1_-_54872059 0.095 ENST00000371320.3
SSBP3
single stranded DNA binding protein 3
chr16_-_71323271 0.095 ENST00000565850.1
ENST00000568910.1
ENST00000434935.2
ENST00000338099.5
CMTR2



cap methyltransferase 2



chr17_+_40834580 0.094 ENST00000264638.4
CNTNAP1
contactin associated protein 1
chr11_-_19263145 0.094 ENST00000532666.1
ENST00000527884.1
E2F8

E2F transcription factor 8

chr9_-_115653176 0.093 ENST00000374228.4
SLC46A2
solute carrier family 46, member 2
chr5_-_157002775 0.093 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr15_+_76135622 0.093 ENST00000338677.4
ENST00000267938.4
ENST00000569423.1
UBE2Q2


ubiquitin-conjugating enzyme E2Q family member 2


chr8_-_144654918 0.092 ENST00000529971.1
MROH6
maestro heat-like repeat family member 6
chr13_+_28712614 0.092 ENST00000380958.3
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr19_-_19739321 0.092 ENST00000588461.1
LPAR2
lysophosphatidic acid receptor 2
chr14_+_74815116 0.089 ENST00000256362.4
VRTN
vertebrae development associated
chr22_+_31892373 0.088 ENST00000443011.1
ENST00000400289.1
ENST00000444859.1
ENST00000400288.2
SFI1



Sfi1 homolog, spindle assembly associated (yeast)



chr17_-_71258491 0.087 ENST00000397671.1
CPSF4L
cleavage and polyadenylation specific factor 4-like
chr16_-_30134524 0.086 ENST00000395202.1
ENST00000395199.3
ENST00000263025.4
ENST00000322266.5
ENST00000403394.1
MAPK3




mitogen-activated protein kinase 3




chr10_-_114206649 0.086 ENST00000369404.3
ENST00000369405.3
ZDHHC6

zinc finger, DHHC-type containing 6

chr13_-_39612176 0.086 ENST00000352251.3
ENST00000350125.3
PROSER1

proline and serine rich 1

chr5_+_61708582 0.086 ENST00000325324.6
IPO11
importin 11
chr10_-_135440296 0.085 ENST00000443774.1
ENST00000425520.1
FRG2B

FSHD region gene 2 family, member B

chr16_-_10674528 0.085 ENST00000359543.3
EMP2
epithelial membrane protein 2
chr6_-_166075557 0.085 ENST00000539869.2
ENST00000366882.1
PDE10A

phosphodiesterase 10A

chr8_+_126442563 0.085 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr3_+_158449972 0.082 ENST00000486568.1
MFSD1
major facilitator superfamily domain containing 1
chr21_+_37692481 0.081 ENST00000400485.1
MORC3
MORC family CW-type zinc finger 3
chr3_+_149530836 0.081 ENST00000466478.1
ENST00000491086.1
ENST00000467977.1
RNF13


ring finger protein 13


chr11_+_61583968 0.081 ENST00000517839.1
FADS2
fatty acid desaturase 2
chr13_+_21714913 0.081 ENST00000450573.1
ENST00000467636.1
SAP18

Sin3A-associated protein, 18kDa

chr21_-_47575481 0.081 ENST00000291670.5
ENST00000397748.1
ENST00000359679.2
ENST00000355384.2
ENST00000397746.3
ENST00000397743.1
FTCD





formimidoyltransferase cyclodeaminase





chr11_-_64013663 0.081 ENST00000392210.2
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr12_-_48152853 0.081 ENST00000171000.4
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr22_+_45072958 0.080 ENST00000403581.1
PRR5
proline rich 5 (renal)
chr2_-_208030886 0.080 ENST00000426163.1
KLF7
Kruppel-like factor 7 (ubiquitous)
chr19_-_45926739 0.080 ENST00000589381.1
ENST00000591636.1
ENST00000013807.5
ENST00000592023.1
ERCC1



excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)



chr7_-_143105941 0.080 ENST00000275815.3
EPHA1
EPH receptor A1
chr12_-_58131931 0.080 ENST00000547588.1
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr10_-_99094458 0.080 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr19_+_10541462 0.080 ENST00000293683.5
PDE4A
phosphodiesterase 4A, cAMP-specific
chr11_-_64512469 0.078 ENST00000377485.1
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr19_-_46145696 0.078 ENST00000588172.1
EML2
echinoderm microtubule associated protein like 2
chr12_-_48152611 0.077 ENST00000389212.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr15_+_29211570 0.077 ENST00000558804.1
APBA2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr11_+_6502675 0.077 ENST00000254616.6
ENST00000530751.1
TIMM10B

translocase of inner mitochondrial membrane 10 homolog B (yeast)

chr19_+_41949054 0.077 ENST00000378187.2
C19orf69
chromosome 19 open reading frame 69
chr15_-_77363375 0.077 ENST00000559494.1
TSPAN3
tetraspanin 3
chr6_+_43112037 0.076 ENST00000473339.1
PTK7
protein tyrosine kinase 7
chr15_-_77363513 0.076 ENST00000267970.4
TSPAN3
tetraspanin 3
chr11_-_65837090 0.075 ENST00000529036.1
RP11-1167A19.2
Uncharacterized protein
chr6_+_111408698 0.075 ENST00000368851.5
SLC16A10
solute carrier family 16 (aromatic amino acid transporter), member 10
chr11_+_809961 0.075 ENST00000530797.1
RPLP2
ribosomal protein, large, P2
chr13_-_111567353 0.074 ENST00000310847.4
ENST00000267339.2
ENST00000375758.5
ANKRD10


ankyrin repeat domain 10


chr15_+_100106244 0.074 ENST00000557942.1
MEF2A
myocyte enhancer factor 2A
chr1_-_155006254 0.074 ENST00000295536.5
DCST2
DC-STAMP domain containing 2
chr5_-_157002749 0.074 ENST00000517905.1
ENST00000430702.2
ENST00000394020.1
ADAM19


ADAM metallopeptidase domain 19


chr16_-_30134266 0.073 ENST00000484663.1
ENST00000478356.1
MAPK3

mitogen-activated protein kinase 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0050894 determination of affect(GO:0050894)
0.1 0.4 GO:1990927 vesicle-mediated cholesterol transport(GO:0090119) short-term synaptic potentiation(GO:1990926) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.4 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.7 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.1 0.5 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.2 GO:0003192 mitral valve formation(GO:0003192)
0.1 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 0.2 GO:0036451 cap mRNA methylation(GO:0036451)
0.1 0.2 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.5 GO:0036018 response to cobalamin(GO:0033590) cellular response to erythropoietin(GO:0036018)
0.1 0.4 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.1 0.2 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.0 0.1 GO:0060166 olfactory pit development(GO:0060166)
0.0 0.9 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.3 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.2 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.0 0.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.8 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.1 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859) uracil metabolic process(GO:0019860) deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.2 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.1 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.3 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.2 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.1 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:1902910 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.0 0.0 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.0 0.1 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.2 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.2 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.2 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.1 GO:1902908 regulation of melanosome transport(GO:1902908)
0.0 0.2 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.0 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.1 GO:0061324 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.2 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005) ERK5 cascade(GO:0070375)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.6 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.1 GO:0034059 response to anoxia(GO:0034059)
0.0 0.1 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.0 0.1 GO:0015793 glycerol transport(GO:0015793)
0.0 1.6 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.2 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.1 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.1 GO:0070836 caveola assembly(GO:0070836)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.0 GO:0060532 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145) negative regulation of beta-amyloid clearance(GO:1900222)
0.0 0.0 GO:0086055 atrial ventricular junction remodeling(GO:0003294) atrial cardiac muscle cell to AV node cell communication by electrical coupling(GO:0086044) bundle of His cell to Purkinje myocyte communication by electrical coupling(GO:0086054) Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling(GO:0086055) regulation of Purkinje myocyte action potential(GO:0098906) vasomotion(GO:1990029)
0.0 0.1 GO:0001999 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001)
0.0 0.2 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.0 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.0 0.0 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.2 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0072244 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.0 0.2 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.0 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.3 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.0 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.1 GO:0071205 protein localization to paranode region of axon(GO:0002175) protein localization to juxtaparanode region of axon(GO:0071205)
0.0 0.0 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.1 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.1 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.0 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0 0.0 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.0 GO:0035933 glucocorticoid secretion(GO:0035933) regulation of glucocorticoid secretion(GO:2000849)
0.0 0.1 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.1 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.1 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.2 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.5 GO:0043196 varicosity(GO:0043196)
0.1 0.4 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.4 GO:0032009 early phagosome(GO:0032009)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0005608 laminin-3 complex(GO:0005608)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.0 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 0.0 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.1 GO:0070369 Scrib-APC-beta-catenin complex(GO:0034750) beta-catenin-TCF7L2 complex(GO:0070369)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0031877 somatostatin receptor binding(GO:0031877)
0.1 0.4 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 1.6 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.1 0.4 GO:1902444 riboflavin binding(GO:1902444)
0.1 0.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 0.8 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.2 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.1 0.9 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.2 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.1 0.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.1 GO:0004324 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0035276 ethanol binding(GO:0035276)
0.0 0.1 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0072544 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.2 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.0 GO:0086079 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling(GO:0086076) gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling(GO:0086078) gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling(GO:0086079)
0.0 0.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.1 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.0 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0051373 FATZ binding(GO:0051373)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.0 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.0 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.0 0.1 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 0.4 ST_STAT3_PATHWAY STAT3 Pathway
0.0 0.2 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.0 0.4 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.4 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.0 REACTOME_CREB_PHOSPHORYLATION_THROUGH_THE_ACTIVATION_OF_RAS Genes involved in CREB phosphorylation through the activation of Ras