Motif ID: TBX21_TBR1

Z-value: 0.441

Transcription factors associated with TBX21_TBR1:

Gene SymbolEntrez IDGene Name
TBR1 ENSG00000136535.10 TBR1
TBX21 ENSG00000073861.2 TBX21

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TBX21hg19_v2_chr17_+_45810594_458106100.609.0e-02Click!
TBR1hg19_v2_chr2_+_162272605_1622727530.373.3e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of TBX21_TBR1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_52685312 0.793 ENST00000327741.5
KRT81
keratin 81
chr2_+_102758271 0.543 ENST00000428279.1
IL1R1
interleukin 1 receptor, type I
chr8_+_75896731 0.533 ENST00000262207.4
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr8_+_120220561 0.515 ENST00000276681.6
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr2_+_102758751 0.498 ENST00000442590.1
IL1R1
interleukin 1 receptor, type I
chr1_-_44482979 0.497 ENST00000360584.2
ENST00000357730.2
ENST00000528803.1
SLC6A9


solute carrier family 6 (neurotransmitter transporter, glycine), member 9


chr12_-_52761262 0.495 ENST00000257901.3
KRT85
keratin 85
chr2_+_102758210 0.470 ENST00000450319.1
IL1R1
interleukin 1 receptor, type I
chr4_-_73434498 0.443 ENST00000286657.4
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr2_+_207139367 0.383 ENST00000374423.3
ZDBF2
zinc finger, DBF-type containing 2
chr12_+_52695617 0.381 ENST00000293525.5
KRT86
keratin 86
chr5_+_140571902 0.377 ENST00000239446.4
PCDHB10
protocadherin beta 10
chr20_+_30193083 0.373 ENST00000376112.3
ENST00000376105.3
ID1

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

chr3_+_42977846 0.362 ENST00000383748.4
KRBOX1
KRAB box domain containing 1
chr12_+_56473939 0.355 ENST00000450146.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr11_+_66790816 0.353 ENST00000527043.1
SYT12
synaptotagmin XII
chrX_+_105412290 0.311 ENST00000357175.2
ENST00000337685.2
MUM1L1

melanoma associated antigen (mutated) 1-like 1

chr4_+_154622652 0.291 ENST00000260010.6
TLR2
toll-like receptor 2
chr2_-_157189180 0.289 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2




nuclear receptor subfamily 4, group A, member 2




chr2_-_177684007 0.289 ENST00000451851.1
AC092162.1
AC092162.1
chr11_-_16430399 0.287 ENST00000528252.1
SOX6
SRY (sex determining region Y)-box 6
chr5_-_49737184 0.277 ENST00000508934.1
ENST00000303221.5
EMB

embigin

chr5_-_88180342 0.262 ENST00000502983.1
MEF2C
myocyte enhancer factor 2C
chr5_+_150040403 0.260 ENST00000517768.1
ENST00000297130.4
MYOZ3

myozenin 3

chr8_+_1993173 0.258 ENST00000523438.1
MYOM2
myomesin 2
chr1_+_38022572 0.256 ENST00000541606.1
DNALI1
dynein, axonemal, light intermediate chain 1
chr10_-_5060147 0.256 ENST00000604507.1
AKR1C2
aldo-keto reductase family 1, member C2
chr4_+_108746282 0.252 ENST00000503862.1
SGMS2
sphingomyelin synthase 2
chr10_-_5060201 0.249 ENST00000407674.1
AKR1C2
aldo-keto reductase family 1, member C2
chr4_+_124317940 0.248 ENST00000505319.1
ENST00000339241.1
SPRY1

sprouty homolog 1, antagonist of FGF signaling (Drosophila)

chr12_-_96184533 0.244 ENST00000343702.4
ENST00000344911.4
NTN4

netrin 4

chr12_-_96184913 0.240 ENST00000538383.1
NTN4
netrin 4
chr6_+_45390222 0.239 ENST00000359524.5
RUNX2
runt-related transcription factor 2
chr14_-_23446900 0.238 ENST00000556731.1
AJUBA
ajuba LIM protein
chrX_-_106146547 0.226 ENST00000276173.4
ENST00000411805.1
RIPPLY1

ripply transcriptional repressor 1

chr19_-_43702231 0.219 ENST00000597374.1
ENST00000599371.1
PSG4

pregnancy specific beta-1-glycoprotein 4

chr19_-_43708378 0.208 ENST00000599746.1
PSG4
pregnancy specific beta-1-glycoprotein 4
chr1_+_28586006 0.200 ENST00000253063.3
SESN2
sestrin 2
chr17_+_25958174 0.196 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
LGALS9



lectin, galactoside-binding, soluble, 9



chr6_+_45389893 0.193 ENST00000371432.3
RUNX2
runt-related transcription factor 2
chr9_+_134378289 0.188 ENST00000423007.1
ENST00000404875.2
ENST00000441334.1
ENST00000341012.7
ENST00000372228.3
ENST00000402686.3
ENST00000419118.2
ENST00000541219.1
ENST00000354713.4
ENST00000418774.1
ENST00000415075.1
ENST00000448212.1
ENST00000430619.1
POMT1












protein-O-mannosyltransferase 1












chr2_+_154728426 0.186 ENST00000392825.3
ENST00000434213.1
GALNT13

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)

chr3_+_167453493 0.184 ENST00000295777.5
ENST00000472747.2
SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

chr11_-_58275578 0.184 ENST00000360374.2
OR5B21
olfactory receptor, family 5, subfamily B, member 21
chr18_-_59561417 0.180 ENST00000591306.1
RNF152
ring finger protein 152
chr3_-_179169330 0.179 ENST00000232564.3
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr17_-_34122596 0.179 ENST00000250144.8
MMP28
matrix metallopeptidase 28
chr6_-_46922659 0.179 ENST00000265417.7
GPR116
G protein-coupled receptor 116
chr2_-_230933709 0.179 ENST00000436869.1
ENST00000295190.4
SLC16A14

solute carrier family 16, member 14

chr8_-_27457494 0.179 ENST00000521770.1
CLU
clusterin
chr17_-_38721711 0.177 ENST00000578085.1
ENST00000246657.2
CCR7

chemokine (C-C motif) receptor 7

chr6_+_32132360 0.177 ENST00000333845.6
ENST00000395512.1
ENST00000432129.1
EGFL8


EGF-like-domain, multiple 8


chr4_+_100495864 0.171 ENST00000265517.5
ENST00000422897.2
MTTP

microsomal triglyceride transfer protein

chr3_+_167453026 0.170 ENST00000472941.1
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr7_-_99766191 0.167 ENST00000423751.1
ENST00000360039.4
GAL3ST4

galactose-3-O-sulfotransferase 4

chr11_+_122709200 0.167 ENST00000227348.4
CRTAM
cytotoxic and regulatory T cell molecule
chr6_-_24646249 0.166 ENST00000430948.2
ENST00000537886.1
ENST00000535378.1
ENST00000378214.3
KIAA0319



KIAA0319



chr11_+_73358690 0.165 ENST00000545798.1
ENST00000539157.1
ENST00000546251.1
ENST00000535582.1
ENST00000538227.1
ENST00000543524.1
PLEKHB1





pleckstrin homology domain containing, family B (evectins) member 1





chr2_-_175869936 0.165 ENST00000409900.3
CHN1
chimerin 1
chr10_-_14596140 0.164 ENST00000496330.1
FAM107B
family with sequence similarity 107, member B
chr11_+_129685707 0.160 ENST00000281441.3
TMEM45B
transmembrane protein 45B
chr1_-_11907829 0.160 ENST00000376480.3
NPPA
natriuretic peptide A
chr17_-_72619869 0.158 ENST00000392619.1
ENST00000426295.2
CD300E

CD300e molecule

chr6_-_26124138 0.156 ENST00000314332.5
ENST00000396984.1
HIST1H2BC

histone cluster 1, H2bc

chr3_+_98216448 0.155 ENST00000427338.1
OR5K2
olfactory receptor, family 5, subfamily K, member 2
chr2_-_175870085 0.154 ENST00000409156.3
CHN1
chimerin 1
chr18_-_30050395 0.153 ENST00000269209.6
ENST00000399218.4
GAREM

GRB2 associated, regulator of MAPK1

chr4_+_26578293 0.151 ENST00000512840.1
TBC1D19
TBC1 domain family, member 19
chr15_-_43559055 0.150 ENST00000220420.5
ENST00000349114.4
TGM5

transglutaminase 5

chr4_+_8582287 0.147 ENST00000382487.4
GPR78
G protein-coupled receptor 78
chr11_+_73358594 0.147 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
PLEKHB1


pleckstrin homology domain containing, family B (evectins) member 1


chr5_+_133861339 0.146 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15


jade family PHD finger 2


chr10_+_24544249 0.144 ENST00000430453.2
KIAA1217
KIAA1217
chr9_-_114557207 0.144 ENST00000374287.3
ENST00000374283.5
C9orf84

chromosome 9 open reading frame 84

chr14_+_32546145 0.142 ENST00000556611.1
ENST00000539826.2
ARHGAP5

Rho GTPase activating protein 5

chr5_-_131132614 0.141 ENST00000307968.7
ENST00000307954.8
FNIP1

folliculin interacting protein 1

chr19_-_7990991 0.140 ENST00000318978.4
CTXN1
cortexin 1
chr8_-_72268721 0.140 ENST00000419131.1
ENST00000388743.2
EYA1

eyes absent homolog 1 (Drosophila)

chr3_+_171844762 0.138 ENST00000443501.1
FNDC3B
fibronectin type III domain containing 3B
chr14_+_32546274 0.137 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr5_-_131132658 0.136 ENST00000511848.1
ENST00000510461.1
ENST00000514667.1
FNIP1

CTC-432M15.3
folliculin interacting protein 1

Folliculin-interacting protein 1
chr22_+_35776828 0.133 ENST00000216117.8
HMOX1
heme oxygenase (decycling) 1
chr11_-_36619771 0.131 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
RAG2


recombination activating gene 2


chr4_+_155484155 0.129 ENST00000509493.1
FGB
fibrinogen beta chain
chr12_-_95942613 0.129 ENST00000393091.2
USP44
ubiquitin specific peptidase 44
chr3_+_142315294 0.128 ENST00000464320.1
PLS1
plastin 1
chr3_+_142315225 0.128 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1





plastin 1





chr10_-_56561022 0.127 ENST00000373965.2
ENST00000414778.1
ENST00000395438.1
ENST00000409834.1
ENST00000395445.1
ENST00000395446.1
ENST00000395442.1
ENST00000395440.1
ENST00000395432.2
ENST00000361849.3
ENST00000395433.1
ENST00000320301.6
ENST00000395430.1
ENST00000437009.1
PCDH15













protocadherin-related 15













chr22_+_35776354 0.125 ENST00000412893.1
HMOX1
heme oxygenase (decycling) 1
chr12_-_95942563 0.124 ENST00000549639.1
ENST00000551837.1
USP44

ubiquitin specific peptidase 44

chr12_+_131438496 0.124 ENST00000543826.1
GPR133
G protein-coupled receptor 133
chr6_-_24645956 0.122 ENST00000543707.1
KIAA0319
KIAA0319
chr11_+_64073699 0.122 ENST00000405666.1
ENST00000468670.1
ESRRA

estrogen-related receptor alpha

chr11_-_1783633 0.122 ENST00000367196.3
CTSD
cathepsin D
chr17_+_38024417 0.120 ENST00000348931.4
ENST00000583811.1
ENST00000584588.1
ENST00000377940.3
ZPBP2



zona pellucida binding protein 2



chr10_+_24498060 0.117 ENST00000376454.3
ENST00000376452.3
KIAA1217

KIAA1217

chr12_-_26278030 0.117 ENST00000242728.4
BHLHE41
basic helix-loop-helix family, member e41
chr19_+_38779778 0.116 ENST00000590738.1
ENST00000587519.2
ENST00000591889.1
SPINT2
CTB-102L5.4

serine peptidase inhibitor, Kunitz type, 2
CTB-102L5.4

chr11_-_114271139 0.113 ENST00000325636.4
C11orf71
chromosome 11 open reading frame 71
chr17_+_25799008 0.112 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
KSR1


kinase suppressor of ras 1


chr12_-_90024360 0.112 ENST00000393164.2
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr12_-_49318715 0.111 ENST00000444214.2
FKBP11
FK506 binding protein 11, 19 kDa
chr8_+_106331769 0.111 ENST00000520492.1
ZFPM2
zinc finger protein, FOG family member 2
chr17_+_35849937 0.110 ENST00000394389.4
DUSP14
dual specificity phosphatase 14
chr9_+_12695702 0.110 ENST00000381136.2
TYRP1
tyrosinase-related protein 1
chr2_-_197675000 0.108 ENST00000342506.2
C2orf66
chromosome 2 open reading frame 66
chr10_+_24497704 0.107 ENST00000376456.4
ENST00000458595.1
KIAA1217

KIAA1217

chr20_+_2517253 0.106 ENST00000358864.1
TMC2
transmembrane channel-like 2
chr8_-_72268968 0.105 ENST00000388740.3
EYA1
eyes absent homolog 1 (Drosophila)
chr8_-_72268889 0.103 ENST00000388742.4
EYA1
eyes absent homolog 1 (Drosophila)
chr10_+_4868460 0.103 ENST00000532248.1
ENST00000345253.5
ENST00000334019.4
AKR1E2


aldo-keto reductase family 1, member E2


chr11_-_82782952 0.102 ENST00000534141.1
RAB30
RAB30, member RAS oncogene family
chr7_-_120497178 0.102 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12


tetraspanin 12


chr1_-_6260896 0.102 ENST00000497965.1
RPL22
ribosomal protein L22
chr12_-_89746264 0.101 ENST00000548755.1
DUSP6
dual specificity phosphatase 6
chr8_-_17941575 0.100 ENST00000417108.2
ASAH1
N-acylsphingosine amidohydrolase (acid ceramidase) 1
chr1_+_154975110 0.100 ENST00000535420.1
ENST00000368426.3
ZBTB7B

zinc finger and BTB domain containing 7B

chr3_-_167452614 0.100 ENST00000392750.2
ENST00000464360.1
ENST00000492139.1
ENST00000471885.1
ENST00000470131.1
PDCD10




programmed cell death 10




chr15_-_38852251 0.097 ENST00000558432.1
RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr19_-_55458860 0.096 ENST00000592784.1
ENST00000448121.2
ENST00000340844.2
NLRP7


NLR family, pyrin domain containing 7


chr1_-_22263790 0.096 ENST00000374695.3
HSPG2
heparan sulfate proteoglycan 2
chr3_-_167452703 0.095 ENST00000497056.2
ENST00000473645.2
PDCD10

programmed cell death 10

chrX_+_51636629 0.095 ENST00000375722.1
ENST00000326587.7
ENST00000375695.2
MAGED1


melanoma antigen family D, 1


chr4_-_168155169 0.095 ENST00000534949.1
ENST00000535728.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr1_+_156105878 0.093 ENST00000508500.1
LMNA
lamin A/C
chrX_+_109245863 0.091 ENST00000372072.3
TMEM164
transmembrane protein 164
chr15_+_59908633 0.091 ENST00000559626.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr2_+_233404429 0.089 ENST00000389494.3
ENST00000389492.3
CHRNG

cholinergic receptor, nicotinic, gamma (muscle)

chr11_+_107799118 0.089 ENST00000320578.2
RAB39A
RAB39A, member RAS oncogene family
chr19_+_859425 0.088 ENST00000327726.6
CFD
complement factor D (adipsin)
chr4_+_87857538 0.087 ENST00000511442.1
AFF1
AF4/FMR2 family, member 1
chr19_+_859654 0.087 ENST00000592860.1
CFD
complement factor D (adipsin)
chr2_+_204192942 0.087 ENST00000295851.5
ENST00000261017.5
ABI2

abl-interactor 2

chr16_+_69139467 0.086 ENST00000569188.1
HAS3
hyaluronan synthase 3
chr19_-_44324750 0.085 ENST00000594049.1
ENST00000414615.2
LYPD5

LY6/PLAUR domain containing 5

chr19_+_46367518 0.084 ENST00000302177.2
FOXA3
forkhead box A3
chr6_+_30585486 0.084 ENST00000259873.4
ENST00000506373.2
MRPS18B

mitochondrial ribosomal protein S18B

chr4_+_108745711 0.082 ENST00000394684.4
SGMS2
sphingomyelin synthase 2
chr11_+_71846764 0.082 ENST00000456237.1
ENST00000442948.2
ENST00000546166.1
FOLR3


folate receptor 3 (gamma)


chr17_-_43502987 0.081 ENST00000376922.2
ARHGAP27
Rho GTPase activating protein 27
chr3_+_185000729 0.080 ENST00000448876.1
ENST00000446828.1
ENST00000447637.1
ENST00000424227.1
ENST00000454237.1
MAP3K13




mitogen-activated protein kinase kinase kinase 13




chr12_-_89746173 0.080 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr17_-_36884451 0.080 ENST00000595377.1
AC006449.1
NS5ATP13TP1; Uncharacterized protein
chr3_+_187896331 0.080 ENST00000392468.2
AC022498.1
Uncharacterized protein
chr1_-_46598371 0.079 ENST00000372006.1
ENST00000425892.1
ENST00000420542.1
ENST00000354242.4
ENST00000340332.6
PIK3R3




phosphoinositide-3-kinase, regulatory subunit 3 (gamma)




chr1_-_76076793 0.079 ENST00000370859.3
SLC44A5
solute carrier family 44, member 5
chr11_-_82782861 0.079 ENST00000524635.1
ENST00000526205.1
ENST00000527633.1
ENST00000533486.1
ENST00000533276.2
RAB30




RAB30, member RAS oncogene family




chr7_+_141490017 0.078 ENST00000247883.4
TAS2R5
taste receptor, type 2, member 5
chr1_-_241799232 0.078 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chr11_-_82611448 0.078 ENST00000393399.2
ENST00000313010.3
PRCP

prolylcarboxypeptidase (angiotensinase C)

chr7_-_76255444 0.077 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr12_-_45269251 0.077 ENST00000553120.1
NELL2
NEL-like 2 (chicken)
chr12_-_45269430 0.076 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr5_+_150639360 0.075 ENST00000523004.1
GM2A
GM2 ganglioside activator
chr2_-_228579305 0.075 ENST00000456524.1
SLC19A3
solute carrier family 19 (thiamine transporter), member 3
chr1_-_76076759 0.074 ENST00000370855.5
SLC44A5
solute carrier family 44, member 5
chr14_+_51026926 0.074 ENST00000557735.1
ATL1
atlastin GTPase 1
chr11_+_65266507 0.074 ENST00000544868.1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chrX_-_10645773 0.073 ENST00000453318.2
MID1
midline 1 (Opitz/BBB syndrome)
chrX_-_10645724 0.072 ENST00000413894.1
MID1
midline 1 (Opitz/BBB syndrome)
chr19_-_43382142 0.072 ENST00000597058.1
PSG1
pregnancy specific beta-1-glycoprotein 1
chr2_+_201994042 0.072 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr9_+_26956474 0.071 ENST00000429045.2
IFT74
intraflagellar transport 74 homolog (Chlamydomonas)
chr11_+_66824303 0.071 ENST00000533360.1
RHOD
ras homolog family member D
chr11_-_76155618 0.070 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr5_-_114515734 0.068 ENST00000514154.1
ENST00000282369.3
TRIM36

tripartite motif containing 36

chr19_-_43530600 0.068 ENST00000598133.1
ENST00000403486.1
ENST00000306322.7
ENST00000401740.1
PSG11



pregnancy specific beta-1-glycoprotein 11



chr11_-_76155700 0.068 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr10_+_118083919 0.067 ENST00000333254.3
CCDC172
coiled-coil domain containing 172
chr11_+_66824346 0.067 ENST00000532559.1
RHOD
ras homolog family member D
chr11_+_66824276 0.067 ENST00000308831.2
RHOD
ras homolog family member D
chrX_+_77166172 0.066 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A


ATPase, Cu++ transporting, alpha polypeptide


chr3_+_195413160 0.066 ENST00000599448.1
LINC00969
long intergenic non-protein coding RNA 969
chr19_-_44405941 0.065 ENST00000587128.1
RP11-15A1.3
RP11-15A1.3
chr5_-_175395283 0.065 ENST00000513482.1
ENST00000265097.4
THOC3

THO complex 3

chr11_-_57519253 0.065 ENST00000422652.1
ENST00000527995.1
BTBD18

BTB (POZ) domain containing 18

chr8_+_1993152 0.064 ENST00000262113.4
MYOM2
myomesin 2
chr1_+_212782012 0.064 ENST00000341491.4
ENST00000366985.1
ATF3

activating transcription factor 3

chr14_+_51026743 0.063 ENST00000358385.6
ENST00000357032.3
ENST00000354525.4
ATL1


atlastin GTPase 1


chrX_+_53449839 0.063 ENST00000457095.1
RIBC1
RIB43A domain with coiled-coils 1
chr8_+_22857048 0.062 ENST00000251822.6
RHOBTB2
Rho-related BTB domain containing 2
chr15_-_80695917 0.062 ENST00000559008.1
RP11-210M15.2
Uncharacterized protein
chr8_+_38586068 0.062 ENST00000443286.2
ENST00000520340.1
ENST00000518415.1
TACC1


transforming, acidic coiled-coil containing protein 1


chr1_-_211752073 0.062 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr5_+_158654712 0.062 ENST00000520323.1
CTB-11I22.2
CTB-11I22.2
chr8_-_99955042 0.061 ENST00000519420.1
STK3
serine/threonine kinase 3
chr14_-_102197445 0.061 ENST00000557778.1
RP11-1029J19.5
RP11-1029J19.5
chr17_+_75084717 0.060 ENST00000561721.2
ENST00000589827.1
ENST00000392476.2
SEC14L1


SEC14-like 1 (S. cerevisiae)


chr8_+_38585704 0.060 ENST00000519416.1
ENST00000520615.1
TACC1

transforming, acidic coiled-coil containing protein 1

chr17_-_39150385 0.060 ENST00000391586.1
KRTAP3-3
keratin associated protein 3-3
chr17_+_79031415 0.059 ENST00000572073.1
ENST00000573677.1
BAIAP2

BAI1-associated protein 2

chr3_+_184032419 0.059 ENST00000352767.3
ENST00000427141.2
EIF4G1

eukaryotic translation initiation factor 4 gamma, 1

chr5_-_149516966 0.059 ENST00000517957.1
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr5_-_137514333 0.059 ENST00000411594.2
ENST00000430331.1
BRD8

bromodomain containing 8

chr7_-_130598059 0.058 ENST00000432045.2
MIR29B1
microRNA 29a
chr1_-_46598284 0.058 ENST00000423209.1
ENST00000262741.5
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr2_+_217498105 0.058 ENST00000233809.4
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr9_+_127023704 0.058 ENST00000373596.1
ENST00000425237.1
NEK6

NIMA-related kinase 6

chr4_+_160188889 0.058 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr6_-_30585009 0.058 ENST00000376511.2
PPP1R10
protein phosphatase 1, regulatory subunit 10

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.5 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.2 0.5 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.3 GO:0032289 central nervous system myelin formation(GO:0032289)
0.1 0.3 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986) general adaptation syndrome(GO:0051866)
0.1 0.5 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.4 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.1 0.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.3 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 0.2 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.1 0.3 GO:0034395 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764) regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.1 0.5 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.2 GO:0060940 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 0.3 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.5 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.3 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.2 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.3 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.2 GO:0001757 somite specification(GO:0001757)
0.0 0.2 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.3 GO:0003172 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.1 GO:0007506 gonadal mesoderm development(GO:0007506)
0.0 0.1 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.3 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.2 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.0 0.1 GO:0070446 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.2 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.2 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.0 0.2 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:0061687 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.0 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.1 GO:0045226 hyaluranon cable assembly(GO:0036118) extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.2 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.0 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.2 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 1.8 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.4 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.0 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:1901297 arterial endothelial cell fate commitment(GO:0060844) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.0 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.3 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.3 GO:1990357 terminal web(GO:1990357)
0.0 1.7 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.1 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.2 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.0 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.2 0.5 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.5 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.1 0.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.1 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.5 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.3 GO:0051373 FATZ binding(GO:0051373)
0.0 0.3 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.1 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.0 0.3 GO:0071723 lipopolysaccharide receptor activity(GO:0001875) lipopeptide binding(GO:0071723)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.5 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.1 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:0005534 galactose binding(GO:0005534)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.6 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.1 GO:0032767 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004992 platelet activating factor receptor activity(GO:0004992) platelet-derived growth factor beta-receptor activity(GO:0005019)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.3 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.0 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 ST_JNK_MAPK_PATHWAY JNK MAPK Pathway
0.0 0.9 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 1.3 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME_AMINE_COMPOUND_SLC_TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.2 REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT Genes involved in Initial triggering of complement