Motif ID: TBX15_MGA

Z-value: 1.254

Transcription factors associated with TBX15_MGA:

Gene SymbolEntrez IDGene Name
MGA ENSG00000174197.12 MGA
TBX15 ENSG00000092607.9 TBX15

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TBX15hg19_v2_chr1_-_119530428_1195305720.501.7e-01Click!
MGAhg19_v2_chr15_+_41952591_419526720.383.1e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of TBX15_MGA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_54281491 3.571 ENST00000381405.4
ESM1
endothelial cell-specific molecule 1
chr5_-_54281407 3.488 ENST00000381403.4
ESM1
endothelial cell-specific molecule 1
chrX_-_138287168 2.911 ENST00000436198.1
FGF13
fibroblast growth factor 13
chr17_+_47296865 2.226 ENST00000573347.1
ABI3
ABI family, member 3
chr1_+_38022513 2.206 ENST00000296218.7
DNALI1
dynein, axonemal, light intermediate chain 1
chr15_+_90319557 1.891 ENST00000341735.3
MESP2
mesoderm posterior 2 homolog (mouse)
chr4_+_183065793 1.804 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr18_-_56296182 1.761 ENST00000361673.3
ALPK2
alpha-kinase 2
chr4_-_186732048 1.589 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2




sorbin and SH3 domain containing 2




chr11_+_7559485 1.555 ENST00000527790.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr20_+_58630972 1.483 ENST00000313426.1
C20orf197
chromosome 20 open reading frame 197
chr3_-_66551351 1.411 ENST00000273261.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr1_-_205290865 1.342 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr17_+_39975544 1.315 ENST00000544340.1
FKBP10
FK506 binding protein 10, 65 kDa
chr3_-_66551397 1.299 ENST00000383703.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr17_+_39975455 1.283 ENST00000455106.1
FKBP10
FK506 binding protein 10, 65 kDa
chr1_-_161039647 1.268 ENST00000368013.3
ARHGAP30
Rho GTPase activating protein 30
chr1_-_161039753 1.260 ENST00000368015.1
ARHGAP30
Rho GTPase activating protein 30
chr1_-_161039456 1.208 ENST00000368016.3
ARHGAP30
Rho GTPase activating protein 30
chr12_+_52431016 1.204 ENST00000553200.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr14_+_78870030 1.090 ENST00000553631.1
ENST00000554719.1
NRXN3

neurexin 3

chr21_+_30502806 1.017 ENST00000399928.1
ENST00000399926.1
MAP3K7CL

MAP3K7 C-terminal like

chr13_-_36429763 1.003 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr5_-_172662303 0.990 ENST00000517440.1
ENST00000329198.4
NKX2-5

NK2 homeobox 5

chr21_+_30503282 0.971 ENST00000399925.1
MAP3K7CL
MAP3K7 C-terminal like
chr5_-_147286065 0.946 ENST00000318315.4
ENST00000515291.1
C5orf46

chromosome 5 open reading frame 46

chr2_-_74776586 0.940 ENST00000420535.1
LOXL3
lysyl oxidase-like 3
chr1_-_156786634 0.935 ENST00000392306.2
ENST00000368199.3
SH2D2A

SH2 domain containing 2A

chr12_+_50451331 0.922 ENST00000228468.4
ASIC1
acid-sensing (proton-gated) ion channel 1
chr17_-_46682321 0.903 ENST00000225648.3
ENST00000484302.2
HOXB6

homeobox B6

chr1_-_156786530 0.902 ENST00000368198.3
SH2D2A
SH2 domain containing 2A
chr12_+_52430894 0.895 ENST00000546842.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr5_-_172662230 0.882 ENST00000424406.2
NKX2-5
NK2 homeobox 5
chr5_-_172662197 0.857 ENST00000521848.1
NKX2-5
NK2 homeobox 5
chr6_-_130182410 0.850 ENST00000368143.1
TMEM244
transmembrane protein 244
chr14_+_95078714 0.815 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3


serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3


chr2_-_27486951 0.808 ENST00000432351.1
SLC30A3
solute carrier family 30 (zinc transporter), member 3
chr4_-_186732241 0.774 ENST00000421639.1
SORBS2
sorbin and SH3 domain containing 2
chr18_+_47088401 0.727 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
LIPG


lipase, endothelial


chr11_+_120081475 0.719 ENST00000328965.4
OAF
OAF homolog (Drosophila)
chr8_-_82395461 0.713 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr2_-_61697862 0.703 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr11_+_86511549 0.683 ENST00000533902.2
PRSS23
protease, serine, 23
chr13_-_46543805 0.681 ENST00000378921.2
ZC3H13
zinc finger CCCH-type containing 13
chr10_+_94451574 0.676 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr7_-_84122033 0.674 ENST00000424555.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr14_+_75746664 0.665 ENST00000557139.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr6_+_7541808 0.651 ENST00000379802.3
DSP
desmoplakin
chr12_-_18890940 0.649 ENST00000543242.1
ENST00000539072.1
ENST00000541966.1
ENST00000266505.7
ENST00000447925.2
ENST00000435379.1
PLCZ1





phospholipase C, zeta 1





chr17_-_47841485 0.643 ENST00000506156.1
ENST00000240364.2
FAM117A

family with sequence similarity 117, member A

chrX_-_32173579 0.636 ENST00000359836.1
ENST00000343523.2
ENST00000378707.3
ENST00000541735.1
ENST00000474231.1
DMD




dystrophin




chr4_-_186456652 0.610 ENST00000284767.5
ENST00000284770.5
PDLIM3

PDZ and LIM domain 3

chr17_+_77021702 0.596 ENST00000392445.2
ENST00000354124.3
C1QTNF1

C1q and tumor necrosis factor related protein 1

chr4_-_186456766 0.585 ENST00000284771.6
PDLIM3
PDZ and LIM domain 3
chr12_+_50451462 0.584 ENST00000447966.2
ASIC1
acid-sensing (proton-gated) ion channel 1
chr12_+_57853918 0.580 ENST00000532291.1
ENST00000543426.1
ENST00000228682.2
ENST00000546141.1
GLI1



GLI family zinc finger 1



chr3_-_100712292 0.576 ENST00000495063.1
ENST00000530539.1
ABI3BP

ABI family, member 3 (NESH) binding protein

chr12_+_52203789 0.568 ENST00000599343.1
AC068987.1
HCG1997999; cDNA FLJ33996 fis, clone DFNES2008881
chr1_+_76540386 0.553 ENST00000328299.3
ST6GALNAC3
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr11_-_133826852 0.546 ENST00000533871.2
ENST00000321016.8
IGSF9B

immunoglobulin superfamily, member 9B

chr6_+_7541845 0.537 ENST00000418664.2
DSP
desmoplakin
chr7_+_140373619 0.526 ENST00000483369.1
ADCK2
aarF domain containing kinase 2
chr3_-_100712352 0.526 ENST00000471714.1
ENST00000284322.5
ABI3BP

ABI family, member 3 (NESH) binding protein

chr9_+_71986182 0.518 ENST00000303068.7
FAM189A2
family with sequence similarity 189, member A2
chr13_-_48575376 0.514 ENST00000434484.1
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr19_+_46531127 0.514 ENST00000601033.1
CTC-344H19.4
CTC-344H19.4
chr6_-_130536774 0.513 ENST00000532763.1
SAMD3
sterile alpha motif domain containing 3
chr3_-_48471454 0.504 ENST00000296440.6
ENST00000448774.2
PLXNB1

plexin B1

chr19_-_14016877 0.501 ENST00000454313.1
ENST00000591586.1
ENST00000346736.2
C19orf57


chromosome 19 open reading frame 57


chr15_+_48483736 0.496 ENST00000559641.1
ENST00000417307.2
SLC12A1
CTXN2
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
cortexin 2
chr3_+_124223586 0.495 ENST00000393496.1
KALRN
kalirin, RhoGEF kinase
chr2_-_25475120 0.495 ENST00000380746.4
ENST00000402667.1
DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha

chr14_+_85994943 0.487 ENST00000553678.1
RP11-497E19.2
Uncharacterized protein
chr17_-_46657473 0.483 ENST00000332503.5
HOXB4
homeobox B4
chr15_+_73344911 0.477 ENST00000560262.1
ENST00000558964.1
NEO1

neogenin 1

chr17_-_39216344 0.476 ENST00000391418.2
KRTAP2-3
keratin associated protein 2-3
chr22_-_31688431 0.475 ENST00000402249.3
ENST00000443175.1
ENST00000215912.5
ENST00000441972.1
PIK3IP1



phosphoinositide-3-kinase interacting protein 1



chr1_+_243419306 0.468 ENST00000355875.4
ENST00000391846.1
ENST00000366541.3
ENST00000343783.6
SDCCAG8



serologically defined colon cancer antigen 8



chr12_-_62586543 0.467 ENST00000416284.3
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr22_-_31688381 0.462 ENST00000487265.2
PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chrX_+_123095546 0.461 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
STAG2


stromal antigen 2


chr15_-_90294523 0.452 ENST00000300057.4
MESP1
mesoderm posterior 1 homolog (mouse)
chr13_-_48575443 0.448 ENST00000378654.3
SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr16_-_67450325 0.444 ENST00000348579.2
ZDHHC1
zinc finger, DHHC-type containing 1
chr8_+_104831472 0.441 ENST00000262231.10
ENST00000507740.1
RIMS2

regulating synaptic membrane exocytosis 2

chr7_-_84121858 0.440 ENST00000448879.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr11_+_18477369 0.435 ENST00000396213.3
ENST00000280706.2
LDHAL6A

lactate dehydrogenase A-like 6A

chr20_+_44657845 0.422 ENST00000243964.3
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr13_-_48575401 0.421 ENST00000433022.1
ENST00000544100.1
SUCLA2

succinate-CoA ligase, ADP-forming, beta subunit

chr1_+_228395755 0.420 ENST00000284548.11
ENST00000570156.2
ENST00000422127.1
ENST00000366707.4
ENST00000366709.4
OBSCN




obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF




chrX_+_135230712 0.419 ENST00000535737.1
FHL1
four and a half LIM domains 1
chr11_-_33891362 0.416 ENST00000395833.3
LMO2
LIM domain only 2 (rhombotin-like 1)
chr2_-_27498186 0.416 ENST00000447008.2
SLC30A3
solute carrier family 30 (zinc transporter), member 3
chr7_-_143929936 0.415 ENST00000391496.1
OR2A42
olfactory receptor, family 2, subfamily A, member 42
chr11_-_115375107 0.414 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1





cell adhesion molecule 1





chr2_+_74648848 0.413 ENST00000409791.1
ENST00000426787.1
ENST00000348227.4
WDR54


WD repeat domain 54


chr11_+_19138670 0.405 ENST00000446113.2
ENST00000399351.3
ZDHHC13

zinc finger, DHHC-type containing 13

chr1_-_113258090 0.404 ENST00000309276.6
PPM1J
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr3_+_52422899 0.404 ENST00000480649.1
DNAH1
dynein, axonemal, heavy chain 1
chr12_+_93965609 0.404 ENST00000549887.1
ENST00000551556.1
SOCS2

suppressor of cytokine signaling 2

chr1_+_155911480 0.403 ENST00000368318.3
RXFP4
relaxin/insulin-like family peptide receptor 4
chr17_-_77179487 0.401 ENST00000580508.1
RBFOX3
RNA binding protein, fox-1 homolog (C. elegans) 3
chr17_-_47308128 0.393 ENST00000413580.1
ENST00000511066.1
PHOSPHO1

phosphatase, orphan 1

chrM_+_10053 0.391 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chrX_+_71354000 0.388 ENST00000510661.1
ENST00000535692.1
NHSL2

NHS-like 2

chr14_+_21467414 0.385 ENST00000554422.1
ENST00000298681.4
SLC39A2

solute carrier family 39 (zinc transporter), member 2

chr21_-_16374688 0.383 ENST00000411932.1
NRIP1
nuclear receptor interacting protein 1
chr17_-_7120498 0.382 ENST00000485100.1
DLG4
discs, large homolog 4 (Drosophila)
chr6_-_160166218 0.379 ENST00000537657.1
SOD2
superoxide dismutase 2, mitochondrial
chr17_-_7120525 0.377 ENST00000447163.1
ENST00000399506.2
ENST00000302955.6
DLG4


discs, large homolog 4 (Drosophila)


chr7_-_143956815 0.377 ENST00000493325.1
OR2A7
olfactory receptor, family 2, subfamily A, member 7
chr11_+_111749650 0.376 ENST00000528125.1
C11orf1
chromosome 11 open reading frame 1
chrX_+_123095890 0.375 ENST00000435215.1
STAG2
stromal antigen 2
chr16_+_77233294 0.372 ENST00000378644.4
SYCE1L
synaptonemal complex central element protein 1-like
chr20_-_1165319 0.370 ENST00000429036.1
TMEM74B
transmembrane protein 74B
chr3_-_55521323 0.368 ENST00000264634.4
WNT5A
wingless-type MMTV integration site family, member 5A
chr4_-_113627966 0.367 ENST00000505632.1
RP11-148B6.2
RP11-148B6.2
chr6_-_138820624 0.367 ENST00000343505.5
NHSL1
NHS-like 1
chr6_-_86099898 0.364 ENST00000455071.1
RP11-30P6.6
RP11-30P6.6
chrX_+_123095860 0.361 ENST00000428941.1
STAG2
stromal antigen 2
chr7_+_143826151 0.358 ENST00000408899.2
OR2A14
olfactory receptor, family 2, subfamily A, member 14
chr1_-_113257905 0.358 ENST00000464951.1
PPM1J
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr22_-_39639021 0.356 ENST00000455790.1
PDGFB
platelet-derived growth factor beta polypeptide
chr2_+_62932779 0.353 ENST00000427809.1
ENST00000405482.1
ENST00000431489.1
EHBP1


EH domain binding protein 1


chr8_+_104831554 0.349 ENST00000408894.2
RIMS2
regulating synaptic membrane exocytosis 2
chr12_-_110011288 0.345 ENST00000540016.1
ENST00000266839.5
MMAB

methylmalonic aciduria (cobalamin deficiency) cblB type

chr15_+_40861487 0.345 ENST00000315616.7
ENST00000559271.1
RPUSD2

RNA pseudouridylate synthase domain containing 2

chr9_+_34990219 0.345 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
DNAJB5


DnaJ (Hsp40) homolog, subfamily B, member 5


chr2_+_62933001 0.343 ENST00000263991.5
ENST00000354487.3
EHBP1

EH domain binding protein 1

chr11_+_111750206 0.338 ENST00000530214.1
ENST00000530799.1
C11orf1

chromosome 11 open reading frame 1

chr14_+_67291158 0.331 ENST00000555456.1
GPHN
gephyrin
chr1_-_37499726 0.328 ENST00000373091.3
ENST00000373093.4
GRIK3

glutamate receptor, ionotropic, kainate 3

chrX_+_12156582 0.328 ENST00000380682.1
FRMPD4
FERM and PDZ domain containing 4
chr12_+_57610562 0.328 ENST00000349394.5
NXPH4
neurexophilin 4
chr11_-_6677018 0.317 ENST00000299441.3
DCHS1
dachsous cadherin-related 1
chr13_+_113548643 0.307 ENST00000375608.3
MCF2L
MCF.2 cell line derived transforming sequence-like
chr12_+_58148842 0.307 ENST00000266643.5
MARCH9
membrane-associated ring finger (C3HC4) 9
chr12_-_82152420 0.307 ENST00000552948.1
ENST00000548586.1
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr12_-_122711968 0.306 ENST00000485724.1
DIABLO
diablo, IAP-binding mitochondrial protein
chr12_-_82153087 0.304 ENST00000547623.1
ENST00000549396.1
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr5_+_140474181 0.296 ENST00000194155.4
PCDHB2
protocadherin beta 2
chr14_+_33408449 0.296 ENST00000346562.2
ENST00000341321.4
ENST00000548645.1
ENST00000356141.4
ENST00000357798.5
NPAS3




neuronal PAS domain protein 3




chrX_+_123095155 0.292 ENST00000371160.1
ENST00000435103.1
STAG2

stromal antigen 2

chr12_+_65672702 0.291 ENST00000538045.1
ENST00000535239.1
MSRB3

methionine sulfoxide reductase B3

chr5_+_113697983 0.291 ENST00000264773.3
KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr12_-_82152444 0.290 ENST00000549325.1
ENST00000550584.2
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr17_-_40833858 0.280 ENST00000332438.4
CCR10
chemokine (C-C motif) receptor 10
chr17_-_39203519 0.280 ENST00000542137.1
ENST00000391419.3
KRTAP2-1

keratin associated protein 2-1

chrX_+_46771711 0.278 ENST00000424392.1
ENST00000397189.1
PHF16

jade family PHD finger 3

chr17_-_39222131 0.276 ENST00000394015.2
KRTAP2-4
keratin associated protein 2-4
chr3_-_39196049 0.273 ENST00000514182.1
CSRNP1
cysteine-serine-rich nuclear protein 1
chr3_-_146213722 0.272 ENST00000336685.2
ENST00000489015.1
PLSCR2

phospholipid scramblase 2

chr7_-_99527243 0.269 ENST00000312891.2
GJC3
gap junction protein, gamma 3, 30.2kDa
chr7_-_127032741 0.268 ENST00000393313.1
ENST00000265827.3
ENST00000434602.1
ZNF800


zinc finger protein 800


chr12_+_57854274 0.268 ENST00000528432.1
GLI1
GLI family zinc finger 1
chr8_-_49833978 0.267 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr8_-_49834299 0.267 ENST00000396822.1
SNAI2
snail family zinc finger 2
chr3_-_99833333 0.266 ENST00000354552.3
ENST00000331335.5
ENST00000398326.2
FILIP1L


filamin A interacting protein 1-like


chr5_-_9630463 0.265 ENST00000382492.2
TAS2R1
taste receptor, type 2, member 1
chrX_+_46771848 0.263 ENST00000218343.4
PHF16
jade family PHD finger 3
chr8_-_101724989 0.260 ENST00000517403.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chrX_-_70473957 0.259 ENST00000373984.3
ENST00000314425.5
ENST00000373982.1
ZMYM3


zinc finger, MYM-type 3


chr7_+_140372953 0.257 ENST00000072869.4
ENST00000476491.1
ADCK2

aarF domain containing kinase 2

chr20_+_13976015 0.257 ENST00000217246.4
MACROD2
MACRO domain containing 2
chr12_+_65672423 0.257 ENST00000355192.3
ENST00000308259.5
ENST00000540804.1
ENST00000535664.1
ENST00000541189.1
MSRB3




methionine sulfoxide reductase B3




chr10_-_16563870 0.255 ENST00000298943.3
C1QL3
complement component 1, q subcomponent-like 3
chr11_-_6426635 0.255 ENST00000608645.1
ENST00000608394.1
ENST00000529519.1
APBB1


amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)


chr11_-_85430163 0.255 ENST00000529581.1
ENST00000533577.1
SYTL2

synaptotagmin-like 2

chr1_+_202995611 0.252 ENST00000367240.2
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr10_-_98945264 0.249 ENST00000314867.5
SLIT1
slit homolog 1 (Drosophila)
chr11_-_85430088 0.249 ENST00000533057.1
ENST00000533892.1
SYTL2

synaptotagmin-like 2

chr7_+_143013198 0.248 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr15_-_66858298 0.248 ENST00000537670.1
LCTL
lactase-like
chr3_-_61237050 0.246 ENST00000476844.1
ENST00000488467.1
ENST00000492590.1
ENST00000468189.1
FHIT



fragile histidine triad



chrX_-_70474377 0.244 ENST00000373978.1
ENST00000373981.1
ZMYM3

zinc finger, MYM-type 3

chr4_+_153021899 0.244 ENST00000509332.1
ENST00000504144.1
ENST00000499452.2
RP11-18H21.1


RP11-18H21.1


chrX_-_70474499 0.243 ENST00000353904.2
ZMYM3
zinc finger, MYM-type 3
chr2_-_74648702 0.242 ENST00000518863.1
C2orf81
chromosome 2 open reading frame 81
chr6_+_108616243 0.237 ENST00000421954.1
LACE1
lactation elevated 1
chr4_-_176733377 0.236 ENST00000505375.1
GPM6A
glycoprotein M6A
chr4_+_144434584 0.235 ENST00000283131.3
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr1_+_154378049 0.233 ENST00000512471.1
IL6R
interleukin 6 receptor
chr11_-_85779971 0.233 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr19_-_10213335 0.233 ENST00000592641.1
ENST00000253109.4
ANGPTL6

angiopoietin-like 6

chr19_+_45973360 0.232 ENST00000589593.1
FOSB
FBJ murine osteosarcoma viral oncogene homolog B
chr18_-_53068911 0.229 ENST00000537856.3
TCF4
transcription factor 4
chr11_-_107590383 0.228 ENST00000525934.1
ENST00000531293.1
SLN

sarcolipin

chr16_-_67965756 0.226 ENST00000571044.1
ENST00000571605.1
CTRL

chymotrypsin-like

chr11_+_8040739 0.226 ENST00000534099.1
TUB
tubby bipartite transcription factor
chr10_-_103454876 0.225 ENST00000331272.7
FBXW4
F-box and WD repeat domain containing 4
chr3_+_160117418 0.223 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
SMC4









structural maintenance of chromosomes 4









chr11_-_85430204 0.221 ENST00000389958.3
ENST00000527794.1
SYTL2

synaptotagmin-like 2

chr1_+_93544791 0.221 ENST00000545708.1
ENST00000540243.1
ENST00000370298.4
MTF2


metal response element binding transcription factor 2


chr6_-_131321863 0.221 ENST00000528282.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr2_+_74881355 0.217 ENST00000357877.2
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr2_+_29033682 0.217 ENST00000379579.4
ENST00000334056.5
ENST00000449210.1
SPDYA


speedy/RINGO cell cycle regulator family member A


chr12_-_50101003 0.216 ENST00000550488.1
FMNL3
formin-like 3
chr22_-_27620603 0.214 ENST00000418271.1
ENST00000444114.1
RP5-1172A22.1

RP5-1172A22.1

chr6_+_79577189 0.214 ENST00000369940.2
IRAK1BP1
interleukin-1 receptor-associated kinase 1 binding protein 1
chr9_-_35815013 0.212 ENST00000259667.5
HINT2
histidine triad nucleotide binding protein 2

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0060929 Purkinje myocyte differentiation(GO:0003168) septum secundum development(GO:0003285) cardiac pacemaker cell fate commitment(GO:0060927) atrioventricular node cell fate commitment(GO:0060929)
0.9 7.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.6 2.6 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.5 2.7 GO:0032474 otolith morphogenesis(GO:0032474)
0.5 1.5 GO:0050915 sensory perception of sour taste(GO:0050915)
0.5 2.9 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.3 1.4 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.3 1.1 GO:1903045 sensory system development(GO:0048880) neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.2 0.7 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.2 0.8 GO:0060032 notochord regression(GO:0060032)
0.2 0.6 GO:0040040 thermosensory behavior(GO:0040040)
0.2 0.9 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.2 0.7 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.2 0.5 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.2 0.9 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2 0.5 GO:1903225 sinoatrial node development(GO:0003163) negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) sinoatrial node cell differentiation(GO:0060921) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012) negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.1 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.1 0.6 GO:0007343 egg activation(GO:0007343)
0.1 0.4 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 1.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 1.6 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.6 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.3 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.1 0.3 GO:0003192 mitral valve formation(GO:0003192)
0.1 0.4 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.1 GO:2000047 regulation of cell-cell adhesion mediated by cadherin(GO:2000047) positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 1.4 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.4 GO:0061349 cardiac right atrium morphogenesis(GO:0003213) chemoattraction of serotonergic neuron axon(GO:0036517) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) negative regulation of cell proliferation in midbrain(GO:1904934) planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation(GO:1904955)
0.1 0.4 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 1.2 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 0.3 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.3 GO:0050758 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.1 0.8 GO:2000821 regulation of grooming behavior(GO:2000821)
0.1 0.5 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 1.8 GO:0097264 self proteolysis(GO:0097264)
0.1 0.2 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.1 0.2 GO:0071106 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) NAD transport(GO:0043132) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.1 0.2 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.1 0.4 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.1 0.6 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.6 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 1.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 0.4 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.4 GO:0036309 protein localization to M-band(GO:0036309)
0.1 0.5 GO:0048539 bone marrow development(GO:0048539)
0.1 0.2 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.8 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 0.3 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.1 0.5 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.5 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.1 0.4 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.9 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 0.2 GO:0001207 histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.1 0.3 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 0.2 GO:1903517 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.1 0.2 GO:0097252 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.1 0.4 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.3 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.5 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.5 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.3 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 0.2 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.7 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.3 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.5 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.2 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:1901340 negative regulation of store-operated calcium channel activity(GO:1901340)
0.0 0.3 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.2 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.8 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.3 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.4 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.1 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.3 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.2 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 1.1 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.3 GO:0035630 bone mineralization involved in bone maturation(GO:0035630)
0.0 0.3 GO:0045060 negative thymic T cell selection(GO:0045060)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.1 GO:0010446 response to alkaline pH(GO:0010446)
0.0 0.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.4 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.2 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.1 GO:0061324 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.0 0.1 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.2 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.1 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.1 GO:0035799 ureter maturation(GO:0035799)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.4 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.1 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.4 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.2 GO:0097396 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.0 0.0 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.4 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.1 GO:0070839 divalent metal ion export(GO:0070839)
0.0 0.9 GO:0006470 protein dephosphorylation(GO:0006470)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.3 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.6 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.0 1.1 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.3 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:0002667 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.0 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.0 0.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 1.3 GO:0001756 somitogenesis(GO:0001756)
0.0 0.0 GO:0046666 retinal cell programmed cell death(GO:0046666)
0.0 1.2 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.0 GO:2000612 pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) thyroid-stimulating hormone secretion(GO:0070460) kidney field specification(GO:0072004) DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240) metanephric nephron tubule formation(GO:0072289) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0044254 angiotensin catabolic process in blood(GO:0002005) multicellular organismal protein catabolic process(GO:0044254) protein digestion(GO:0044256) multicellular organismal macromolecule catabolic process(GO:0044266)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.0 0.1 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0 0.1 GO:0051095 regulation of helicase activity(GO:0051095)
0.0 0.1 GO:0071351 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.0 0.1 GO:0007512 adult heart development(GO:0007512)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.3 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.0 GO:1902338 regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072039) negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072040) mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:1901145) negative regulation of apoptotic process involved in morphogenesis(GO:1902338) negative regulation of somatic stem cell population maintenance(GO:1904673) negative regulation of apoptotic process involved in development(GO:1904746)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.1 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.2 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.1 GO:0043588 skin development(GO:0043588)
0.0 0.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.3 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.4 GO:0036156 inner dynein arm(GO:0036156)
0.1 0.7 GO:0035976 AP1 complex(GO:0035976)
0.1 0.7 GO:0098839 postsynaptic density membrane(GO:0098839)
0.1 0.2 GO:0031213 RSF complex(GO:0031213)
0.1 0.6 GO:0016013 syntrophin complex(GO:0016013)
0.0 0.4 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.5 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.5 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 1.5 GO:0030057 desmosome(GO:0030057)
0.0 1.0 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.5 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.1 GO:0035101 FACT complex(GO:0035101)
0.0 0.1 GO:0042025 host cell nucleus(GO:0042025)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.5 GO:0001741 XY body(GO:0001741)
0.0 4.0 GO:0030175 filopodium(GO:0030175)
0.0 0.2 GO:0051286 cell tip(GO:0051286)
0.0 0.3 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 1.0 GO:0045095 keratin filament(GO:0045095)
0.0 0.9 GO:0097546 ciliary base(GO:0097546)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 3.4 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.3 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 3.1 GO:0030018 Z disc(GO:0030018)
0.0 0.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.6 2.8 GO:0010736 serum response element binding(GO:0010736)
0.4 1.2 GO:0015633 zinc transporting ATPase activity(GO:0015633)
0.4 1.5 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.3 0.9 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.3 1.4 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.2 0.8 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2 0.5 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.1 0.4 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.4 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.1 0.3 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.1 0.9 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.4 GO:1902379 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.1 1.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.4 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.3 GO:0016768 spermine synthase activity(GO:0016768)
0.1 1.1 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.5 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.2 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 2.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 0.4 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.7 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.1 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.6 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.2 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.1 0.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.3 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 2.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.6 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.4 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0071633 dihydroceramidase activity(GO:0071633)
0.0 0.3 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 0.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.2 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 2.4 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 4.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.5 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.5 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.2 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.1 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.8 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.1 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.4 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.1 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.3 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.1 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.0 0.2 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.0 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 1.6 GO:0005518 collagen binding(GO:0005518)
0.0 1.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0097001 ceramide binding(GO:0097001)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.3 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 3.7 PID_ERBB4_PATHWAY ErbB4 signaling events
0.0 0.7 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.5 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 ST_STAT3_PATHWAY STAT3 Pathway
0.0 0.9 PID_EPHB_FWD_PATHWAY EPHB forward signaling
0.0 0.4 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.7 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.8 PID_VEGFR1_2_PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 1.5 PID_AJDISS_2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.4 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.6 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.3 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.0 0.7 PID_AURORA_B_PATHWAY Aurora B signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 1.4 REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.1 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.9 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.8 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.8 REACTOME_PIP3_ACTIVATES_AKT_SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 1.0 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.9 REACTOME_MEIOTIC_SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.2 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.3 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 4.2 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.5 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.6 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 2.0 REACTOME_SIGNALING_BY_EGFR_IN_CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.4 REACTOME_SYNTHESIS_OF_PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME_DEADENYLATION_OF_MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.6 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.0 REACTOME_OLFACTORY_SIGNALING_PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.8 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.8 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.4 REACTOME_MYOGENESIS Genes involved in Myogenesis