Motif ID: TBX1

Z-value: 0.774


Transcription factors associated with TBX1:

Gene SymbolEntrez IDGene Name
TBX1 ENSG00000184058.8 TBX1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TBX1hg19_v2_chr22_+_19744226_19744226-0.665.4e-02Click!


Activity profile for motif TBX1.

activity profile for motif TBX1


Sorted Z-values histogram for motif TBX1

Sorted Z-values for motif TBX1



Network of associatons between targets according to the STRING database.



First level regulatory network of TBX1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_150400124 1.956 ENST00000388825.4
ENST00000521650.1
ENST00000517973.1
GPX3


glutathione peroxidase 3 (plasma)


chr12_-_52685312 1.924 ENST00000327741.5
KRT81
keratin 81
chr17_-_19648916 1.288 ENST00000444455.1
ENST00000439102.2
ALDH3A1

aldehyde dehydrogenase 3 family, member A1

chr3_+_167453026 1.069 ENST00000472941.1
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr2_+_102758271 1.067 ENST00000428279.1
IL1R1
interleukin 1 receptor, type I
chr8_+_120220561 1.052 ENST00000276681.6
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr16_-_28550348 1.035 ENST00000324873.6
NUPR1
nuclear protein, transcriptional regulator, 1
chr2_+_102758751 1.032 ENST00000442590.1
IL1R1
interleukin 1 receptor, type I
chr10_-_46970533 1.017 ENST00000512997.1
SYT15
synaptotagmin XV
chr12_-_10022735 0.957 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr2_+_102758210 0.954 ENST00000450319.1
IL1R1
interleukin 1 receptor, type I
chr19_-_36822551 0.868 ENST00000591372.1
LINC00665
long intergenic non-protein coding RNA 665
chr8_+_75896731 0.861 ENST00000262207.4
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr8_-_27457494 0.861 ENST00000521770.1
CLU
clusterin
chr3_+_42977846 0.848 ENST00000383748.4
KRBOX1
KRAB box domain containing 1
chr12_-_71551868 0.839 ENST00000247829.3
TSPAN8
tetraspanin 8
chr12_+_52695617 0.808 ENST00000293525.5
KRT86
keratin 86
chr12_-_71551652 0.807 ENST00000546561.1
TSPAN8
tetraspanin 8
chr1_+_207070775 0.796 ENST00000391929.3
ENST00000294984.2
ENST00000367093.3
IL24


interleukin 24


chr19_-_43702231 0.789 ENST00000597374.1
ENST00000599371.1
PSG4

pregnancy specific beta-1-glycoprotein 4

chr5_-_49737184 0.770 ENST00000508934.1
ENST00000303221.5
EMB

embigin

chr22_+_35776354 0.763 ENST00000412893.1
HMOX1
heme oxygenase (decycling) 1
chr10_-_5060147 0.741 ENST00000604507.1
AKR1C2
aldo-keto reductase family 1, member C2
chr11_+_66790816 0.738 ENST00000527043.1
SYT12
synaptotagmin XII
chr4_+_154622652 0.724 ENST00000260010.6
TLR2
toll-like receptor 2
chr4_+_72204755 0.721 ENST00000512686.1
ENST00000340595.3
SLC4A4

solute carrier family 4 (sodium bicarbonate cotransporter), member 4

chr10_-_5060201 0.708 ENST00000407674.1
AKR1C2
aldo-keto reductase family 1, member C2
chr5_-_149792295 0.704 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74



CD74 molecule, major histocompatibility complex, class II invariant chain



chr16_-_28550320 0.704 ENST00000395641.2
NUPR1
nuclear protein, transcriptional regulator, 1
chr10_-_46970474 0.667 ENST00000503753.1
ENST00000374321.4
SYT15

synaptotagmin XV

chr2_-_192016316 0.645 ENST00000358470.4
ENST00000432798.1
ENST00000450994.1
STAT4


signal transducer and activator of transcription 4


chr22_+_35776828 0.637 ENST00000216117.8
HMOX1
heme oxygenase (decycling) 1
chrX_+_105937068 0.618 ENST00000324342.3
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chrX_-_154563889 0.607 ENST00000369449.2
ENST00000321926.4
CLIC2

chloride intracellular channel 2

chr7_-_81635106 0.605 ENST00000443883.1
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr1_+_26503894 0.586 ENST00000361530.6
ENST00000374253.5
CNKSR1

connector enhancer of kinase suppressor of Ras 1

chr11_+_71846764 0.564 ENST00000456237.1
ENST00000442948.2
ENST00000546166.1
FOLR3


folate receptor 3 (gamma)


chr3_+_167453493 0.550 ENST00000295777.5
ENST00000472747.2
SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

chr14_+_105939276 0.549 ENST00000483017.3
CRIP2
cysteine-rich protein 2
chr12_-_95942563 0.540 ENST00000549639.1
ENST00000551837.1
USP44

ubiquitin specific peptidase 44

chr4_-_152329987 0.535 ENST00000508847.1
RP11-610P16.1
RP11-610P16.1
chr11_-_1783633 0.530 ENST00000367196.3
CTSD
cathepsin D
chr1_-_11107280 0.530 ENST00000400897.3
ENST00000400898.3
MASP2

mannan-binding lectin serine peptidase 2

chr19_-_58629742 0.521 ENST00000595721.1
ENST00000600404.1
ENST00000595944.1
ZSCAN18


zinc finger and SCAN domain containing 18


chr7_+_134212312 0.512 ENST00000359579.4
AKR1B10
aldo-keto reductase family 1, member B10 (aldose reductase)
chr19_-_55458860 0.506 ENST00000592784.1
ENST00000448121.2
ENST00000340844.2
NLRP7


NLR family, pyrin domain containing 7


chr4_-_168155577 0.504 ENST00000541354.1
ENST00000509854.1
ENST00000512681.1
ENST00000421836.2
ENST00000510741.1
ENST00000510403.1
SPOCK3





sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3





chr19_-_58446721 0.504 ENST00000396147.1
ENST00000595569.1
ENST00000599852.1
ENST00000425570.3
ENST00000601593.1
ZNF418




zinc finger protein 418




chr19_+_50979753 0.500 ENST00000597426.1
ENST00000334976.6
ENST00000376918.3
ENST00000598585.1
EMC10



ER membrane protein complex subunit 10



chr11_-_17035943 0.490 ENST00000355661.3
ENST00000532079.1
ENST00000448080.2
ENST00000531066.1
PLEKHA7



pleckstrin homology domain containing, family A member 7



chr19_+_18492973 0.489 ENST00000595973.2
GDF15
growth differentiation factor 15
chr5_+_133861339 0.487 ENST00000282605.4
ENST00000361895.2
ENST00000402835.1
PHF15


jade family PHD finger 2


chr6_+_36922209 0.487 ENST00000373674.3
PI16
peptidase inhibitor 16
chr2_-_207078086 0.483 ENST00000442134.1
GPR1
G protein-coupled receptor 1
chr12_-_95942613 0.475 ENST00000393091.2
USP44
ubiquitin specific peptidase 44
chrX_+_105936982 0.475 ENST00000418562.1
RNF128
ring finger protein 128, E3 ubiquitin protein ligase
chr9_-_139891165 0.470 ENST00000494426.1
CLIC3
chloride intracellular channel 3
chr12_-_121477039 0.469 ENST00000257570.5
OASL
2'-5'-oligoadenylate synthetase-like
chr12_-_121476959 0.462 ENST00000339275.5
OASL
2'-5'-oligoadenylate synthetase-like
chr4_-_168155700 0.459 ENST00000357545.4
ENST00000512648.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr12_-_121476750 0.454 ENST00000543677.1
OASL
2'-5'-oligoadenylate synthetase-like
chr8_+_1993173 0.451 ENST00000523438.1
MYOM2
myomesin 2
chr19_-_46526304 0.451 ENST00000008938.4
PGLYRP1
peptidoglycan recognition protein 1
chr14_-_54418598 0.447 ENST00000609748.1
ENST00000558961.1
BMP4

bone morphogenetic protein 4

chr1_-_44482979 0.439 ENST00000360584.2
ENST00000357730.2
ENST00000528803.1
SLC6A9


solute carrier family 6 (neurotransmitter transporter, glycine), member 9


chr15_-_75017711 0.436 ENST00000567032.1
ENST00000564596.1
ENST00000566503.1
ENST00000395049.4
ENST00000395048.2
ENST00000379727.3
CYP1A1





cytochrome P450, family 1, subfamily A, polypeptide 1





chr16_-_55866997 0.432 ENST00000360526.3
ENST00000361503.4
CES1

carboxylesterase 1

chr2_+_154728426 0.429 ENST00000392825.3
ENST00000434213.1
GALNT13

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)

chr1_+_60280458 0.421 ENST00000455990.1
ENST00000371208.3
HOOK1

hook microtubule-tethering protein 1

chr4_-_73434498 0.420 ENST00000286657.4
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr2_+_33701286 0.419 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr11_-_1782625 0.417 ENST00000438213.1
CTSD
cathepsin D
chr15_+_81071684 0.417 ENST00000220244.3
ENST00000394685.3
ENST00000356249.5
KIAA1199


KIAA1199


chr1_+_17531614 0.406 ENST00000375471.4
PADI1
peptidyl arginine deiminase, type I
chr9_+_77230499 0.404 ENST00000396204.2
RORB
RAR-related orphan receptor B
chr2_-_207078154 0.404 ENST00000447845.1
GPR1
G protein-coupled receptor 1
chr2_-_162931052 0.401 ENST00000360534.3
DPP4
dipeptidyl-peptidase 4
chr2_+_42275153 0.400 ENST00000294964.5
PKDCC
protein kinase domain containing, cytoplasmic
chr10_+_91061712 0.399 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr4_+_91048706 0.397 ENST00000509176.1
CCSER1
coiled-coil serine-rich protein 1
chrX_+_9880412 0.396 ENST00000418909.2
SHROOM2
shroom family member 2
chr2_-_230933709 0.394 ENST00000436869.1
ENST00000295190.4
SLC16A14

solute carrier family 16, member 14

chr2_-_228579305 0.394 ENST00000456524.1
SLC19A3
solute carrier family 19 (thiamine transporter), member 3
chr7_+_73245193 0.393 ENST00000340958.2
CLDN4
claudin 4
chr12_+_56473939 0.387 ENST00000450146.2
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr1_-_153518270 0.385 ENST00000354332.4
ENST00000368716.4
S100A4

S100 calcium binding protein A4

chr6_+_121756809 0.384 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr2_+_102759199 0.381 ENST00000409288.1
ENST00000410023.1
IL1R1

interleukin 1 receptor, type I

chr10_+_24544249 0.379 ENST00000430453.2
KIAA1217
KIAA1217
chr1_-_109203685 0.378 ENST00000402983.1
ENST00000420055.1
HENMT1

HEN1 methyltransferase homolog 1 (Arabidopsis)

chrX_+_1387721 0.376 ENST00000419094.1
ENST00000381509.3
ENST00000494969.2
ENST00000355805.2
ENST00000355432.3
CSF2RA




colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)




chr19_+_38779778 0.374 ENST00000590738.1
ENST00000587519.2
ENST00000591889.1
SPINT2
CTB-102L5.4

serine peptidase inhibitor, Kunitz type, 2
CTB-102L5.4

chr20_+_12989822 0.374 ENST00000378194.4
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr8_-_57232656 0.371 ENST00000396721.2
SDR16C5
short chain dehydrogenase/reductase family 16C, member 5
chr9_+_140119618 0.368 ENST00000359069.2
C9orf169
chromosome 9 open reading frame 169
chr1_-_169680745 0.366 ENST00000236147.4
SELL
selectin L
chrX_+_1387693 0.364 ENST00000381529.3
ENST00000432318.2
ENST00000361536.3
ENST00000501036.2
ENST00000381524.3
ENST00000412290.1
CSF2RA





colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)





chr17_+_25958174 0.361 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
LGALS9



lectin, galactoside-binding, soluble, 9



chr3_-_185270342 0.360 ENST00000424591.2
LIPH
lipase, member H
chr20_+_12989596 0.360 ENST00000434210.1
ENST00000399002.2
SPTLC3

serine palmitoyltransferase, long chain base subunit 3

chr4_+_165675197 0.359 ENST00000515485.1
RP11-294O2.2
RP11-294O2.2
chr9_+_12693336 0.359 ENST00000381137.2
ENST00000388918.5
TYRP1

tyrosinase-related protein 1

chr17_-_191188 0.354 ENST00000575634.1
RPH3AL
rabphilin 3A-like (without C2 domains)
chr6_+_125475335 0.350 ENST00000532429.1
ENST00000534199.1
TPD52L1

tumor protein D52-like 1

chr8_-_150563 0.345 ENST00000523795.2
RP11-585F1.10
Protein LOC100286914
chr22_-_36013368 0.345 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB



myoglobin



chr1_-_31902614 0.345 ENST00000596131.1
AC114494.1
HCG1787699; Uncharacterized protein
chr18_-_47376197 0.340 ENST00000592688.1
MYO5B
myosin VB
chr1_-_183538319 0.336 ENST00000420553.1
ENST00000419402.1
NCF2

neutrophil cytosolic factor 2

chr1_-_151345159 0.335 ENST00000458566.1
ENST00000447402.3
ENST00000426705.2
ENST00000435071.1
ENST00000368868.5
SELENBP1




selenium binding protein 1




chr4_+_108746282 0.333 ENST00000503862.1
SGMS2
sphingomyelin synthase 2
chr19_+_16771936 0.333 ENST00000187762.2
ENST00000599479.1
TMEM38A

transmembrane protein 38A

chr9_+_140122018 0.332 ENST00000445101.2
RNF224
ring finger protein 224
chr3_-_171528227 0.332 ENST00000356327.5
ENST00000342215.6
ENST00000340989.4
ENST00000351298.4
PLD1



phospholipase D1, phosphatidylcholine-specific



chr3_-_178969403 0.332 ENST00000314235.5
ENST00000392685.2
KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

chr11_-_76155618 0.330 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr19_+_8429031 0.330 ENST00000301455.2
ENST00000541807.1
ENST00000393962.2
ANGPTL4


angiopoietin-like 4


chr20_+_12989895 0.330 ENST00000450297.1
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr1_+_169077133 0.324 ENST00000494797.1
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr1_+_169077172 0.323 ENST00000499679.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr3_-_13461807 0.320 ENST00000254508.5
NUP210
nucleoporin 210kDa
chr11_-_119993979 0.319 ENST00000524816.3
ENST00000525327.1
TRIM29

tripartite motif containing 29

chr2_-_157189180 0.318 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2




nuclear receptor subfamily 4, group A, member 2




chr5_+_150639360 0.316 ENST00000523004.1
GM2A
GM2 ganglioside activator
chr19_-_58864848 0.312 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chr20_-_22565101 0.311 ENST00000419308.2
FOXA2
forkhead box A2
chr6_+_26158343 0.310 ENST00000377777.4
ENST00000289316.2
HIST1H2BD

histone cluster 1, H2bd

chr2_+_10560147 0.309 ENST00000422133.1
HPCAL1
hippocalcin-like 1
chr2_+_176972000 0.307 ENST00000249504.5
HOXD11
homeobox D11
chr9_+_125137565 0.306 ENST00000373698.5
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chrX_-_48693955 0.305 ENST00000218230.5
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr7_+_142982023 0.304 ENST00000359333.3
ENST00000409244.1
ENST00000409541.1
ENST00000410004.1
TMEM139



transmembrane protein 139



chr2_-_152955537 0.303 ENST00000201943.5
ENST00000539935.1
CACNB4

calcium channel, voltage-dependent, beta 4 subunit

chr3_+_171844762 0.302 ENST00000443501.1
FNDC3B
fibronectin type III domain containing 3B
chr5_+_140571902 0.301 ENST00000239446.4
PCDHB10
protocadherin beta 10
chr2_+_186603545 0.300 ENST00000424728.1
FSIP2
fibrous sheath interacting protein 2
chr10_-_46970573 0.299 ENST00000374325.3
SYT15
synaptotagmin XV
chr2_-_27718052 0.295 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chr8_-_17941575 0.292 ENST00000417108.2
ASAH1
N-acylsphingosine amidohydrolase (acid ceramidase) 1
chr4_-_168155730 0.291 ENST00000502330.1
ENST00000357154.3
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr16_+_19222479 0.291 ENST00000568433.1
SYT17
synaptotagmin XVII
chr10_-_92681033 0.290 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr11_+_71846748 0.289 ENST00000445078.2
FOLR3
folate receptor 3 (gamma)
chr11_+_121322832 0.288 ENST00000260197.7
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr19_+_36195429 0.288 ENST00000392197.2
ZBTB32
zinc finger and BTB domain containing 32
chr3_+_98216448 0.288 ENST00000427338.1
OR5K2
olfactory receptor, family 5, subfamily K, member 2
chr1_-_36789755 0.288 ENST00000270824.1
EVA1B
eva-1 homolog B (C. elegans)
chrX_-_55515635 0.287 ENST00000500968.3
USP51
ubiquitin specific peptidase 51
chr6_+_160693591 0.282 ENST00000419196.1
RP1-276N6.2
RP1-276N6.2
chr20_+_43343886 0.280 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr3_+_184055240 0.280 ENST00000383847.2
FAM131A
family with sequence similarity 131, member A
chr5_-_141257954 0.279 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
PCDH1



protocadherin 1



chr2_+_207139367 0.278 ENST00000374423.3
ZDBF2
zinc finger, DBF-type containing 2
chr2_-_179672142 0.278 ENST00000342992.6
ENST00000360870.5
ENST00000460472.2
ENST00000589042.1
ENST00000591111.1
ENST00000342175.6
ENST00000359218.5
TTN






titin






chr19_+_56915668 0.277 ENST00000333201.9
ENST00000391778.3
ZNF583

zinc finger protein 583

chr1_-_53608249 0.276 ENST00000371494.4
SLC1A7
solute carrier family 1 (glutamate transporter), member 7
chr2_-_152955213 0.276 ENST00000427385.1
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr15_+_26147507 0.275 ENST00000383019.2
ENST00000557171.1
RP11-1084I9.1

RP11-1084I9.1

chr18_-_30050395 0.274 ENST00000269209.6
ENST00000399218.4
GAREM

GRB2 associated, regulator of MAPK1

chr8_-_19540266 0.274 ENST00000311540.4
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chrX_-_106146547 0.272 ENST00000276173.4
ENST00000411805.1
RIPPLY1

ripply transcriptional repressor 1

chr6_-_75828774 0.272 ENST00000493109.2
COL12A1
collagen, type XII, alpha 1
chr9_-_114362093 0.272 ENST00000538962.1
ENST00000407693.2
ENST00000238248.3
PTGR1


prostaglandin reductase 1


chr14_-_105635090 0.271 ENST00000331782.3
ENST00000347004.2
JAG2

jagged 2

chr11_-_58275578 0.269 ENST00000360374.2
OR5B21
olfactory receptor, family 5, subfamily B, member 21
chr2_-_170219037 0.269 ENST00000443831.1
LRP2
low density lipoprotein receptor-related protein 2
chr4_-_798689 0.268 ENST00000504062.1
CPLX1
complexin 1
chr2_+_30455016 0.267 ENST00000401506.1
ENST00000407930.2
LBH

limb bud and heart development

chr8_+_1993152 0.267 ENST00000262113.4
MYOM2
myomesin 2
chr12_+_75874984 0.266 ENST00000550491.1
GLIPR1
GLI pathogenesis-related 1
chr9_+_130911723 0.266 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2


lipocalin 2


chr5_+_140560980 0.265 ENST00000361016.2
PCDHB16
protocadherin beta 16
chr8_-_33330595 0.264 ENST00000524021.1
ENST00000335589.3
FUT10

fucosyltransferase 10 (alpha (1,3) fucosyltransferase)

chr3_-_169482840 0.263 ENST00000602385.1
TERC
telomerase RNA component
chr2_+_169926047 0.263 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
DHRS9


dehydrogenase/reductase (SDR family) member 9


chr17_-_38721711 0.262 ENST00000578085.1
ENST00000246657.2
CCR7

chemokine (C-C motif) receptor 7

chr8_-_19615538 0.262 ENST00000517494.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr6_-_26124138 0.261 ENST00000314332.5
ENST00000396984.1
HIST1H2BC

histone cluster 1, H2bc

chr19_-_36822595 0.260 ENST00000585356.1
ENST00000438368.2
ENST00000590622.1
LINC00665


long intergenic non-protein coding RNA 665


chr15_+_59908633 0.258 ENST00000559626.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr14_+_74083548 0.258 ENST00000381139.1
ACOT6
acyl-CoA thioesterase 6
chr1_+_38022572 0.258 ENST00000541606.1
DNALI1
dynein, axonemal, light intermediate chain 1
chr2_+_233404429 0.258 ENST00000389494.3
ENST00000389492.3
CHRNG

cholinergic receptor, nicotinic, gamma (muscle)

chr4_+_155484103 0.258 ENST00000302068.4
FGB
fibrinogen beta chain
chr11_-_76155700 0.256 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr14_+_51026926 0.255 ENST00000557735.1
ATL1
atlastin GTPase 1
chr19_+_859425 0.255 ENST00000327726.6
CFD
complement factor D (adipsin)
chr10_-_14596140 0.251 ENST00000496330.1
FAM107B
family with sequence similarity 107, member B
chr10_+_4868460 0.249 ENST00000532248.1
ENST00000345253.5
ENST00000334019.4
AKR1E2


aldo-keto reductase family 1, member E2


chr2_-_192016276 0.249 ENST00000413064.1
STAT4
signal transducer and activator of transcription 4
chr4_+_156824840 0.248 ENST00000536354.2
TDO2
tryptophan 2,3-dioxygenase
chr9_+_40028620 0.248 ENST00000426179.1
AL353791.1
AL353791.1
chr21_-_43771226 0.247 ENST00000291526.4
TFF2
trefoil factor 2
chr7_-_76255444 0.247 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr1_-_24194771 0.245 ENST00000374479.3
FUCA1
fucosidase, alpha-L- 1, tissue
chr8_-_33455268 0.245 ENST00000522982.1
DUSP26
dual specificity phosphatase 26 (putative)
chr7_+_141490017 0.245 ENST00000247883.4
TAS2R5
taste receptor, type 2, member 5
chr7_+_139478030 0.244 ENST00000425687.1
ENST00000263552.6
ENST00000438104.1
ENST00000336425.5
TBXAS1



thromboxane A synthase 1 (platelet)



chr6_+_36646435 0.243 ENST00000244741.5
ENST00000405375.1
ENST00000373711.2
CDKN1A


cyclin-dependent kinase inhibitor 1A (p21, Cip1)


chr11_+_64073699 0.240 ENST00000405666.1
ENST00000468670.1
ESRRA

estrogen-related receptor alpha


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.4 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.5 0.5 GO:0006714 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
0.4 1.4 GO:0006788 heme oxidation(GO:0006788)
0.3 2.0 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.2 0.7 GO:0032289 central nervous system myelin formation(GO:0032289)
0.2 1.4 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.2 0.5 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.1 0.6 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.1 0.4 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.7 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.1 0.4 GO:0008057 eye pigment granule organization(GO:0008057)
0.1 0.6 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.6 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.1 0.4 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.1 0.5 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.1 1.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.8 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 0.7 GO:0007500 mesodermal cell fate determination(GO:0007500)
0.1 0.9 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 1.9 GO:2000194 regulation of female gonad development(GO:2000194)
0.1 0.3 GO:0007037 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.1 0.3 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986) general adaptation syndrome(GO:0051866)
0.1 0.4 GO:0035803 egg coat formation(GO:0035803)
0.1 0.5 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.1 0.3 GO:1902996 regulation of neurofibrillary tangle assembly(GO:1902996)
0.1 0.4 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.1 0.1 GO:1901295 regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 0.8 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 0.6 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.1 1.8 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.6 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.4 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.1 0.3 GO:0042361 menaquinone catabolic process(GO:0042361) vitamin K catabolic process(GO:0042377)
0.1 0.7 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.1 0.4 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.4 GO:0036343 psychomotor behavior(GO:0036343)
0.1 0.1 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.1 0.3 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.1 1.1 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 0.6 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 0.2 GO:0038169 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.1 0.2 GO:0070446 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.1 0.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.1 GO:0018205 peptidyl-lysine modification(GO:0018205)
0.1 0.2 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.2 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.2 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 0.3 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.6 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.2 GO:0072011 glomerular endothelium development(GO:0072011)
0.1 0.1 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.3 GO:0035995 skeletal muscle myosin thick filament assembly(GO:0030241) detection of muscle stretch(GO:0035995)
0.1 0.1 GO:0021539 subthalamus development(GO:0021539)
0.1 0.8 GO:0015884 folic acid transport(GO:0015884)
0.1 0.3 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.1 0.4 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.2 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 0.4 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.3 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.8 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.1 0.3 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.1 0.2 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.1 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 1.0 GO:0046520 sphingoid biosynthetic process(GO:0046520)
0.1 0.8 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.2 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 0.4 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 0.2 GO:0042704 uterine wall breakdown(GO:0042704)
0.1 0.1 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.0 0.0 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.2 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.0 0.3 GO:2000252 negative regulation of feeding behavior(GO:2000252)
0.0 0.2 GO:0048806 genitalia development(GO:0048806)
0.0 0.1 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.0 0.2 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.1 GO:0030816 positive regulation of cAMP metabolic process(GO:0030816)
0.0 0.2 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.0 0.3 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0 0.1 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.3 GO:0001757 somite specification(GO:0001757)
0.0 0.3 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.0 0.4 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.4 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.2 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.0 0.3 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.3 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0033319 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.0 0.2 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.3 GO:0032439 endosome localization(GO:0032439)
0.0 0.5 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.3 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.1 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.0 0.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.2 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.1 GO:0035482 gastric motility(GO:0035482) gastric emptying(GO:0035483) positive regulation of growth rate(GO:0040010) negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.2 GO:0097327 response to antineoplastic agent(GO:0097327)
0.0 0.1 GO:0006043 glucosamine catabolic process(GO:0006043)
0.0 0.3 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.6 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.0 0.3 GO:0022605 oogenesis stage(GO:0022605)
0.0 0.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.8 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.3 GO:1990034 calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.4 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.5 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.1 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.0 0.4 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0090032 negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.0 0.2 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.3 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.0 0.4 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.3 GO:1902430 negative regulation of beta-amyloid formation(GO:1902430)
0.0 0.1 GO:0060981 cell migration involved in coronary angiogenesis(GO:0060981)
0.0 0.1 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.1 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.0 0.2 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.1 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.2 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.2 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.4 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0009447 putrescine catabolic process(GO:0009447)
0.0 0.1 GO:0050764 regulation of phagocytosis(GO:0050764)
0.0 0.0 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.3 GO:0034127 regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034127)
0.0 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0097009 energy homeostasis(GO:0097009)
0.0 0.1 GO:0003409 optic cup structural organization(GO:0003409)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 0.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.1 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.2 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0 3.0 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.1 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.2 GO:1903788 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.1 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.0 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.4 GO:0015871 choline transport(GO:0015871)
0.0 0.0 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.0 0.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.1 GO:0032570 response to progesterone(GO:0032570)
0.0 0.1 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.0 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.2 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.2 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.1 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.7 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.1 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.1 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.1 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.4 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015) inositol lipid-mediated signaling(GO:0048017)
0.0 0.1 GO:0046364 hexose biosynthetic process(GO:0019319) monosaccharide biosynthetic process(GO:0046364)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.1 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0 0.0 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.1 GO:1901079 dense core granule biogenesis(GO:0061110) positive regulation of relaxation of muscle(GO:1901079) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.1 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.1 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.1 GO:0061591 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.1 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0045226 hyaluranon cable assembly(GO:0036118) extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.1 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.0 GO:0090024 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.2 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 1.4 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:0033594 response to hydroxyisoflavone(GO:0033594)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.2 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.6 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.4 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.0 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.1 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.1 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.1 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.0 0.2 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 1.2 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 1.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.0 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.2 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.2 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.3 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.2 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 1.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.0 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.0 GO:0051466 positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.4 GO:0071174 mitotic spindle checkpoint(GO:0071174)
0.0 0.1 GO:0032252 secretory granule localization(GO:0032252)
0.0 1.5 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.8 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 0.6 GO:0001523 retinoid metabolic process(GO:0001523)
0.0 0.0 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.0 0.0 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0 0.2 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 1.0 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.0 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.0 0.3 GO:0045332 phospholipid translocation(GO:0045332)
0.0 0.2 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0 0.0 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 1.3 GO:0007422 peripheral nervous system development(GO:0007422)
0.0 0.1 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.1 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 0.0 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.0 0.0 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.3 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.0 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.1 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.2 GO:0010002 cardioblast differentiation(GO:0010002)
0.0 0.2 GO:0022401 desensitization of G-protein coupled receptor protein signaling pathway(GO:0002029) negative adaptation of signaling pathway(GO:0022401)
0.0 0.2 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.1 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.1 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0021681 cerebellar granular layer development(GO:0021681)
0.0 0.0 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778) regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.5 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.1 0.3 GO:0005595 collagen type XII trimer(GO:0005595)
0.1 0.7 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.3 GO:0045179 apical cortex(GO:0045179)
0.1 1.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 1.0 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 0.3 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 0.5 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.1 0.2 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.3 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.2 GO:0034515 proteasome storage granule(GO:0034515)
0.1 0.5 GO:1990357 terminal web(GO:1990357)
0.1 0.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.4 GO:0070695 FHF complex(GO:0070695)
0.0 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.6 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.4 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 2.3 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.5 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0033263 CORVET complex(GO:0033263)
0.0 0.8 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.0 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.2 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0019008 molybdopterin synthase complex(GO:0019008)
0.0 0.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 2.3 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 1.0 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 0.2 GO:0071546 pi-body(GO:0071546)
0.0 0.1 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.2 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.3 GO:0043219 lateral loop(GO:0043219)
0.0 0.1 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.4 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0030893 meiotic cohesin complex(GO:0030893)
0.0 0.1 GO:0044609 DBIRD complex(GO:0044609)
0.0 0.1 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 1.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.1 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.3 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.3 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.0 GO:0044452 nucleolar part(GO:0044452)
0.0 0.1 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0036338 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.0 1.3 GO:0005901 caveola(GO:0005901)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.2 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.0 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0097342 ripoptosome(GO:0097342)
0.0 0.2 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.3 GO:0042629 mast cell granule(GO:0042629)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 0.5 GO:0047718 geranylgeranyl reductase activity(GO:0045550) indanol dehydrogenase activity(GO:0047718)
0.5 3.4 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.4 1.4 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 1.4 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)
0.2 0.6 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.2 0.5 GO:0001855 complement component C4b binding(GO:0001855)
0.1 0.6 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.1 0.4 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 1.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 1.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.6 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.7 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.4 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 1.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.8 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 0.5 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 0.4 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.5 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 1.7 GO:0008430 selenium binding(GO:0008430)
0.1 0.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.4 GO:0030305 beta-glucuronidase activity(GO:0004566) heparanase activity(GO:0030305)
0.1 0.3 GO:0032440 2-alkenal reductase [NAD(P)] activity(GO:0032440)
0.1 0.7 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.3 GO:0050333 thiamin-triphosphatase activity(GO:0050333)
0.1 0.4 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.3 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 0.2 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.1 0.6 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.2 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.2 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.2 GO:0033961 cis-stilbene-oxide hydrolase activity(GO:0033961)
0.1 0.2 GO:0038131 neuregulin receptor activity(GO:0038131)
0.1 0.2 GO:0050135 NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.1 0.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 1.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.2 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.1 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.1 1.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.7 GO:0031433 telethonin binding(GO:0031433)
0.1 0.2 GO:0004766 spermidine synthase activity(GO:0004766)
0.1 0.3 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.2 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.2 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 0.4 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.1 0.2 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.1 0.2 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.1 0.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.1 0.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.2 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.4 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.2 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.0 0.0 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0 0.4 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.4 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0048040 UDP-glucuronate decarboxylase activity(GO:0048040)
0.0 0.8 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.8 GO:0005542 folic acid binding(GO:0005542)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.9 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.3 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 1.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.4 GO:0071253 connexin binding(GO:0071253)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0052591 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.1 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.1 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.0 0.1 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.0 0.2 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.9 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.3 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.4 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.3 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.1 GO:0070996 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783) type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.1 GO:0005019 platelet-derived growth factor beta-receptor activity(GO:0005019)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.6 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.3 GO:0031994 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.0 0.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 2.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.1 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.1 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.0 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.1 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.2 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.0 0.1 GO:0020037 heme binding(GO:0020037)
0.0 0.3 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.0 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.0 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.3 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.2 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.0 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.1 GO:0070697 activin receptor binding(GO:0070697) type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 0.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.2 GO:0045503 dynein light chain binding(GO:0045503)
0.0 0.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.0 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.0 GO:0045118 azole transporter activity(GO:0045118) azole transmembrane transporter activity(GO:1901474)
0.0 0.0 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.0 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 3.8 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 1.7 PID_IL23_PATHWAY IL23-mediated signaling events
0.0 2.1 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 0.6 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 2.7 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.2 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.8 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 1.0 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.6 PID_NCADHERIN_PATHWAY N-cadherin signaling events
0.0 0.3 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 0.3 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 0.3 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.0 PID_LKB1_PATHWAY LKB1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.8 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 3.6 REACTOME_IL1_SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.2 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.5 REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.3 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.7 REACTOME_MTORC1_MEDIATED_SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.4 REACTOME_SIGNALING_BY_ACTIVATED_POINT_MUTANTS_OF_FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.5 REACTOME_COMMON_PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.4 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 0.2 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.8 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.6 REACTOME_HS_GAG_DEGRADATION Genes involved in HS-GAG degradation
0.0 0.3 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.5 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 0.9 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME_REGULATION_OF_THE_FANCONI_ANEMIA_PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.2 REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.6 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 0.2 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.6 REACTOME_SPHINGOLIPID_DE_NOVO_BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.7 REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.8 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.2 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.1 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation